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Conserved domains on  [gi|4757812|ref|NP_004880|]
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ATP synthase subunit f, mitochondrial isoform 2a [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WRW super family cl10896
Mitochondrial F1F0-ATP synthase, subunit f; This is a family of small proteins of ...
 14-89 6.16e-21

Mitochondrial F1F0-ATP synthase, subunit f; This is a family of small proteins of approximately 110 amino acids, which are highly conserved from nematodes to humans. Some members of the family have been annotated in Swiss-Prot as being the f subunit of mitochondrial F1F0-ATP synthase but this could not be confirmed. The sequence has a well-conserved WRW motif. The exact function of the protein is not known.


The actual alignment was detected with superfamily member pfam10206:

Pssm-ID: 431134  Cd Length: 102  Bit Score: 79.26  E-value: 6.16e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 4757812     14 KDKKLLEVKLGELPSWILMRDFSPSGIFGAFQRGYYRYYNKYINVKKGSISGITMVLACYVLFSYSFSYKHLKHER 89
Cdd:pfam10206  26 PDTPFGDVKLGELPSWLGRRNKTPSAFAGAFSRAFWRWQHKYVQPKRTGIAPFFQVTFAFMAFFYVINYKKLKHHR 101
 
Name Accession Description Interval E-value
WRW pfam10206
Mitochondrial F1F0-ATP synthase, subunit f; This is a family of small proteins of ...
 14-89 6.16e-21

Mitochondrial F1F0-ATP synthase, subunit f; This is a family of small proteins of approximately 110 amino acids, which are highly conserved from nematodes to humans. Some members of the family have been annotated in Swiss-Prot as being the f subunit of mitochondrial F1F0-ATP synthase but this could not be confirmed. The sequence has a well-conserved WRW motif. The exact function of the protein is not known.


Pssm-ID: 431134  Cd Length: 102  Bit Score: 79.26  E-value: 6.16e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 4757812     14 KDKKLLEVKLGELPSWILMRDFSPSGIFGAFQRGYYRYYNKYINVKKGSISGITMVLACYVLFSYSFSYKHLKHER 89
Cdd:pfam10206  26 PDTPFGDVKLGELPSWLGRRNKTPSAFAGAFSRAFWRWQHKYVQPKRTGIAPFFQVTFAFMAFFYVINYKKLKHHR 101
 
Name Accession Description Interval E-value
WRW pfam10206
Mitochondrial F1F0-ATP synthase, subunit f; This is a family of small proteins of ...
 14-89 6.16e-21

Mitochondrial F1F0-ATP synthase, subunit f; This is a family of small proteins of approximately 110 amino acids, which are highly conserved from nematodes to humans. Some members of the family have been annotated in Swiss-Prot as being the f subunit of mitochondrial F1F0-ATP synthase but this could not be confirmed. The sequence has a well-conserved WRW motif. The exact function of the protein is not known.


Pssm-ID: 431134  Cd Length: 102  Bit Score: 79.26  E-value: 6.16e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 4757812     14 KDKKLLEVKLGELPSWILMRDFSPSGIFGAFQRGYYRYYNKYINVKKGSISGITMVLACYVLFSYSFSYKHLKHER 89
Cdd:pfam10206  26 PDTPFGDVKLGELPSWLGRRNKTPSAFAGAFSRAFWRWQHKYVQPKRTGIAPFFQVTFAFMAFFYVINYKKLKHHR 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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