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Conserved domains on  [gi|6319263|ref|NP_009346|]
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ubiquitin-protein transferase activating protein PEX22 [Saccharomyces cerevisiae S288C]

Protein Classification

peroxisome assembly protein 22( domain architecture ID 10582012)

peroxisome assembly protein 22 (PEX22) is involved in peroxisome biogenesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Peroxin-22 pfam12827
Peroxisomal biogenesis protein family; Peroxin-22 is a integral peroxisomal membrane protein ...
 51-167 2.28e-24

Peroxisomal biogenesis protein family; Peroxin-22 is a integral peroxisomal membrane protein family. The N-terminus is in the matrix and the C-terminus is in the cytosol. The N-terminus carries a 25-amino acid peroxisome membrane-targeting signal. It interacts with the ubiquitin-conjugating peripheral peroxisomal membrane enzyme Pex4p anchoring it at the peroxisomal membrane. Both Pex proteins are involved at the same stage of peroxisome biogenesis.


:

Pssm-ID: 403894  Cd Length: 109  Bit Score: 91.59  E-value: 2.28e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319263     51 SVKENKKARKSKCIIMSKSIQGLP-IKWEEYAADEVVLLVPTSHTDGSMKQaigDAFRKTKNEHKIIYCDSMDGLWSCVR 129
Cdd:pfam12827   2 KSIKKKYTNKSKCVVLTQSILDVSqLDWNELLSEDVVFILPPNVTKDDLNI---ESEVSSGNEYKIIRCDTIQGYWSCVK 78

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 6319263    130 RLGKFQCILNSRDFTSSggsdaavVPEDIGRFVKFVVD 167
Cdd:pfam12827  79 HLKPDQLLVCSDDLGDG-------IPADLNRFVKNIIE 109
 
Name Accession Description Interval E-value
Peroxin-22 pfam12827
Peroxisomal biogenesis protein family; Peroxin-22 is a integral peroxisomal membrane protein ...
 51-167 2.28e-24

Peroxisomal biogenesis protein family; Peroxin-22 is a integral peroxisomal membrane protein family. The N-terminus is in the matrix and the C-terminus is in the cytosol. The N-terminus carries a 25-amino acid peroxisome membrane-targeting signal. It interacts with the ubiquitin-conjugating peripheral peroxisomal membrane enzyme Pex4p anchoring it at the peroxisomal membrane. Both Pex proteins are involved at the same stage of peroxisome biogenesis.


Pssm-ID: 403894  Cd Length: 109  Bit Score: 91.59  E-value: 2.28e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319263     51 SVKENKKARKSKCIIMSKSIQGLP-IKWEEYAADEVVLLVPTSHTDGSMKQaigDAFRKTKNEHKIIYCDSMDGLWSCVR 129
Cdd:pfam12827   2 KSIKKKYTNKSKCVVLTQSILDVSqLDWNELLSEDVVFILPPNVTKDDLNI---ESEVSSGNEYKIIRCDTIQGYWSCVK 78

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 6319263    130 RLGKFQCILNSRDFTSSggsdaavVPEDIGRFVKFVVD 167
Cdd:pfam12827  79 HLKPDQLLVCSDDLGDG-------IPADLNRFVKNIIE 109
 
Name Accession Description Interval E-value
Peroxin-22 pfam12827
Peroxisomal biogenesis protein family; Peroxin-22 is a integral peroxisomal membrane protein ...
 51-167 2.28e-24

Peroxisomal biogenesis protein family; Peroxin-22 is a integral peroxisomal membrane protein family. The N-terminus is in the matrix and the C-terminus is in the cytosol. The N-terminus carries a 25-amino acid peroxisome membrane-targeting signal. It interacts with the ubiquitin-conjugating peripheral peroxisomal membrane enzyme Pex4p anchoring it at the peroxisomal membrane. Both Pex proteins are involved at the same stage of peroxisome biogenesis.


Pssm-ID: 403894  Cd Length: 109  Bit Score: 91.59  E-value: 2.28e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319263     51 SVKENKKARKSKCIIMSKSIQGLP-IKWEEYAADEVVLLVPTSHTDGSMKQaigDAFRKTKNEHKIIYCDSMDGLWSCVR 129
Cdd:pfam12827   2 KSIKKKYTNKSKCVVLTQSILDVSqLDWNELLSEDVVFILPPNVTKDDLNI---ESEVSSGNEYKIIRCDTIQGYWSCVK 78

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 6319263    130 RLGKFQCILNSRDFTSSggsdaavVPEDIGRFVKFVVD 167
Cdd:pfam12827  79 HLKPDQLLVCSDDLGDG-------IPADLNRFVKNIIE 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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