|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
302-846 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 799.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 302 TIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQdSNEEIRISFCTN--CKSKGPFRVNGEK 379
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQ-SGRETEPTVCPPreCQSPTPFSLNHER 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 380 TVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNN-YDGNLNAKNGFPVFATIIEANSIKR 458
Cdd:smart00350 80 STFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVpYGFKLNTVKGLPVFATYIEANHVRK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 459 REGNTANEGEEGLdVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDIN 538
Cdd:smart00350 160 LDYKRSFEDSSFS-VQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGDIN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 539 VLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRT 618
Cdd:smart00350 239 ILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSDRT 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 619 SIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATF 698
Cdd:smart00350 319 AIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELAKH 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 699 VVDSHVRSHPENDEDREGeelknngesaieqgedeineqlnarqrrlqrqrkkeeeisPIPQELLMKYIHYARTKIYPKL 778
Cdd:smart00350 399 VVDLHRYSHPEEDEAFEP----------------------------------------PLSQEKLRKYIAYAREKIKPKL 438
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6319448 779 HQMDMDKVSRVYADLRRESIST---GSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFV 846
Cdd:smart00350 439 SEEAADKLVKAYVDLRKEDSQTesrSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
496-844 |
0e+00 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 661.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 496 KIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVG 575
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 576 LTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGG 655
Cdd:cd17753 81 LTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 656 RYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSHPENDEDREGEELKNngesaiEQGEDEin 735
Cdd:cd17753 161 RYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHPENDEDREGEEEKN------QRQRPK-- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 736 eqlnarqrrlqrqrkkEEEISPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGSFPITVRHLESILR 815
Cdd:cd17753 233 ----------------ETKVEPIPQELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGSLPITVRHLESIIR 296
|
330 340
....*....|....*....|....*....
gi 6319448 816 IAESFAKMRLSEFVSSYDLDRAIKVVVDS 844
Cdd:cd17753 297 ISEAHAKMHLREYVSEEDVDMAIRVMLDS 325
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
210-841 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 560.19 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 210 ELKSFLLEYTdetgrsvYGARIRTLGEMNSE--SLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAMEATELhypDYA 287
Cdd:COG1241 8 KFEEFLRRYK-------YRDEILELAQEYPEkrSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLE---PYD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 288 RIHSEIHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILgPFFQDSNEEIRISFCTNC 367
Cdd:COG1241 78 VSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTET-YVPQTGEKLQEPHECPGC 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 368 KSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNLNAKNgfPVF 447
Cdd:COG1241 157 GRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRGKS--TIF 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 448 ATIIEANSIKRREgntaNEGEEgLDVfswTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNV 527
Cdd:COG1241 235 DLYLEANSIEVEE----KEFEE-IEI---TEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVL 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 528 NGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTAS-VRKDPITKEWTLEGGALVLADKGVCLI 606
Cdd:COG1241 307 PDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAaVRDDFGTGRWTLEAGALVLADGGLACI 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 607 DEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDL 686
Cdd:COG1241 387 DELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDK 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 687 VDEEADERLATFVVDSHvrshpendedREGEELknngESAIEQGEDEINeqlnarqrrlqrqrkkeeeiSPIPQELLMKY 766
Cdd:COG1241 467 PDEERDRELARHILKVH----------RAGELL----EQEIEEETEEVK--------------------PEIDPDLLRKY 512
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6319448 767 IHYARTKIYPKLHQMDMDKVSRVYADLRRESIS-TGSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVV 841
Cdd:COG1241 513 IAYARRNVFPVLTEEAKDLIEDFYVDMRKKGEDeDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLV 588
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
210-839 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 558.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 210 ELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAMEATELHYPDYARI 289
Cdd:NF040949 4 KFKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEYAEE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 290 HSEIHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCG--SILGPFFQDSNEEI-RISFCTN 366
Cdd:NF040949 84 VAKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGceFEWPEEEEESYEIVePPTVCPV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 367 CKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNLnAKNGFPV 446
Cdd:NF040949 164 CGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDSSL-KKGSRPI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 447 FATIIEANSIKRREgntaNEGEEgldvFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKN 526
Cdd:NF040949 243 FKNYIEANHIEVSQ----KELEE----VEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 527 VNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLI 606
Cdd:NF040949 315 LPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVI 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 607 DEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDL 686
Cdd:NF040949 395 DEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDK 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 687 VDEEADERLATFVVDSHvrshpendedregeelknngesaieqgedeineqlnarqrrlqrqrKKEEEISP-IPQELLMK 765
Cdd:NF040949 475 PNEERDRRLARHILDVH----------------------------------------------SGKEKVKPeIDPDLLKK 508
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6319448 766 YIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGS----FPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIK 839
Cdd:NF040949 509 YIAYARKYVRPKLTEEAKKLIEDFYVEMRKSSKSSEDpdspIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIR 586
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
480-703 |
1.33e-141 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 418.47 E-value: 1.33e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 480 EEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKT 559
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 560 AHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTT 639
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6319448 640 LQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSH 703
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
255-841 |
3.30e-87 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 297.29 E-value: 3.30e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 255 ILALFLAKCPEEMLKIFDLVAMEATELHYPDYARIHSEIH--VRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFP 332
Cdd:PTZ00111 165 LLVTFPADCIAELDKVLVKLFNELLSKHYSDLSLENNSFFprARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQTWIVP 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 333 QLKYVKFNCLKCGSILGPFFQDSNEEI----------RISFCTNCKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRL 402
Cdd:PTZ00111 245 EITMACFRCRGQKKIGLNDYQPCTCEHyeyviqgevnEPLLCNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDK 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 403 P-----------------RHREVI---LLADLVDVSKPGEEVEVTGIYK------NNYDGNLNAKngFPVFATIIEANSI 456
Cdd:PTZ00111 325 DgldnsvdnsglngeiymKDNEVInlnLYDDLIDSVKTGDRVTVVGILKvtpirtSTTRRTLKSL--YTYFVNVIHVKVI 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 457 KRREGNTANEGEEGL-DVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSI-- 533
Cdd:PTZ00111 403 NSTNANQPEKGLKYLgNENDFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGNKNSSDFNKSPda 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 534 -------RGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVR-KDPITKEWTLEGGALVLADKGVCL 605
Cdd:PTZ00111 483 cykvdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIKfNESDNGRAMIQPGAVVLANGGVCC 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 606 IDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRD 685
Cdd:PTZ00111 563 IDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLD 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 686 LVDEEADERLATFVVDSHVRSH---PENDEDREGEELKNNGESAIEQGEDEINEQlnarqrrlqrqrkkeeeispiPQEL 762
Cdd:PTZ00111 643 HIDQDTDQLISLSIAKDFLLPHmtgSGNDEDTYDRSNTMHVEDESLRSEKDYNKN---------------------DLDM 701
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 763 LMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESIST----------------------GSFPITV--RHLESILRIAE 818
Cdd:PTZ00111 702 LRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNFQTsnldelehaqedddddlyyqssGTRMIYVssRMISSIIRISV 781
|
650 660
....*....|....*....|...
gi 6319448 819 SFAKMRLSEFVSSYDLDRAIKVV 841
Cdd:PTZ00111 782 SLARMRLSTVVTPADALQAVQIV 804
|
|
| MCM2_N |
pfam12619 |
Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is ... |
49-193 |
7.54e-24 |
|
Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is typically between 138 and 153 amino acids in length. The family is found in association with pfam00493. Mini-chromosome maintenance (MCM) proteins are essential for DNA replication. These proteins use ATPase activity to perform this function.
Pssm-ID: 403724 Cd Length: 148 Bit Score: 98.25 E-value: 7.54e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 49 EGDDNEVD--DVPDIDEVEEQMNEVDLMDDNMYEDYAADHNRDRYDPDQVDDR-EQQELSLSERRRIDAQLNERDRLLRN 125
Cdd:pfam12619 1 EDEEAEIDenDIDDLDPDEEEEDGEDLFGDNMEDDYRQNPELDRYDLDDIDDEgDYEEMDAAERRRAEAQLNRRDRELGA 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6319448 126 V------AYIDDEDEEQEGaaqLDEMGLPVQRRRRRRQYEDLENsdddLLSDMDIDPLREELTLESLSNVKANS 193
Cdd:pfam12619 81 ArrrrpaAFLQDDDDEDDL---DGDYGLPIQRRRRRRHYDEDQD----EDMDEDIDPFEEELSLESLADVKADS 147
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
209-299 |
2.30e-16 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 75.02 E-value: 2.30e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 209 RELKSFLLEYT-DETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAME--ATELHYPD 285
Cdd:pfam14551 2 RKFKDFLEEFReDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEvvKELSEDPD 81
|
90
....*....|....
gi 6319448 286 YARIHSEIHVRISD 299
Cdd:pfam14551 82 YAEEEKEFQVRFYN 95
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
302-846 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 799.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 302 TIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQdSNEEIRISFCTN--CKSKGPFRVNGEK 379
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQ-SGRETEPTVCPPreCQSPTPFSLNHER 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 380 TVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNN-YDGNLNAKNGFPVFATIIEANSIKR 458
Cdd:smart00350 80 STFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVpYGFKLNTVKGLPVFATYIEANHVRK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 459 REGNTANEGEEGLdVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDIN 538
Cdd:smart00350 160 LDYKRSFEDSSFS-VQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGDIN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 539 VLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRT 618
Cdd:smart00350 239 ILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSDRT 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 619 SIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATF 698
Cdd:smart00350 319 AIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELAKH 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 699 VVDSHVRSHPENDEDREGeelknngesaieqgedeineqlnarqrrlqrqrkkeeeisPIPQELLMKYIHYARTKIYPKL 778
Cdd:smart00350 399 VVDLHRYSHPEEDEAFEP----------------------------------------PLSQEKLRKYIAYAREKIKPKL 438
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6319448 779 HQMDMDKVSRVYADLRRESIST---GSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFV 846
Cdd:smart00350 439 SEEAADKLVKAYVDLRKEDSQTesrSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
496-844 |
0e+00 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 661.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 496 KIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVG 575
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 576 LTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGG 655
Cdd:cd17753 81 LTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 656 RYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSHPENDEDREGEELKNngesaiEQGEDEin 735
Cdd:cd17753 161 RYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHPENDEDREGEEEKN------QRQRPK-- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 736 eqlnarqrrlqrqrkkEEEISPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGSFPITVRHLESILR 815
Cdd:cd17753 233 ----------------ETKVEPIPQELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGSLPITVRHLESIIR 296
|
330 340
....*....|....*....|....*....
gi 6319448 816 IAESFAKMRLSEFVSSYDLDRAIKVVVDS 844
Cdd:cd17753 297 ISEAHAKMHLREYVSEEDVDMAIRVMLDS 325
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
210-841 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 560.19 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 210 ELKSFLLEYTdetgrsvYGARIRTLGEMNSE--SLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAMEATELhypDYA 287
Cdd:COG1241 8 KFEEFLRRYK-------YRDEILELAQEYPEkrSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLE---PYD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 288 RIHSEIHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILgPFFQDSNEEIRISFCTNC 367
Cdd:COG1241 78 VSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTET-YVPQTGEKLQEPHECPGC 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 368 KSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNLNAKNgfPVF 447
Cdd:COG1241 157 GRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRGKS--TIF 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 448 ATIIEANSIKRREgntaNEGEEgLDVfswTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNV 527
Cdd:COG1241 235 DLYLEANSIEVEE----KEFEE-IEI---TEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVL 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 528 NGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTAS-VRKDPITKEWTLEGGALVLADKGVCLI 606
Cdd:COG1241 307 PDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAaVRDDFGTGRWTLEAGALVLADGGLACI 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 607 DEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDL 686
Cdd:COG1241 387 DELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDK 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 687 VDEEADERLATFVVDSHvrshpendedREGEELknngESAIEQGEDEINeqlnarqrrlqrqrkkeeeiSPIPQELLMKY 766
Cdd:COG1241 467 PDEERDRELARHILKVH----------RAGELL----EQEIEEETEEVK--------------------PEIDPDLLRKY 512
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6319448 767 IHYARTKIYPKLHQMDMDKVSRVYADLRRESIS-TGSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVV 841
Cdd:COG1241 513 IAYARRNVFPVLTEEAKDLIEDFYVDMRKKGEDeDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLV 588
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
210-839 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 558.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 210 ELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAMEATELHYPDYARI 289
Cdd:NF040949 4 KFKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEYAEE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 290 HSEIHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCG--SILGPFFQDSNEEI-RISFCTN 366
Cdd:NF040949 84 VAKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGceFEWPEEEEESYEIVePPTVCPV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 367 CKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNLnAKNGFPV 446
Cdd:NF040949 164 CGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDSSL-KKGSRPI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 447 FATIIEANSIKRREgntaNEGEEgldvFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKN 526
Cdd:NF040949 243 FKNYIEANHIEVSQ----KELEE----VEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 527 VNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLI 606
Cdd:NF040949 315 LPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVI 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 607 DEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDL 686
Cdd:NF040949 395 DEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDK 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 687 VDEEADERLATFVVDSHvrshpendedregeelknngesaieqgedeineqlnarqrrlqrqrKKEEEISP-IPQELLMK 765
Cdd:NF040949 475 PNEERDRRLARHILDVH----------------------------------------------SGKEKVKPeIDPDLLKK 508
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6319448 766 YIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGS----FPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIK 839
Cdd:NF040949 509 YIAYARKYVRPKLTEEAKKLIEDFYVEMRKSSKSSEDpdspIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIR 586
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
496-844 |
4.52e-162 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 474.52 E-value: 4.52e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 496 KIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVG 575
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 576 LTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGG 655
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 656 RYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSHPENdedregeelknngesaieqgedein 735
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDPEE------------------------- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 736 eqlnarqrrlqrQRKKEEEISPIPQELLMKYIHYARtKIYPKLHQMDMDKVSRVYADLRRESISTGSFPITVRHLESILR 815
Cdd:cd17706 216 ------------QVKPEEDGIPIDIELLRKYILYAR-QIHPKISEEAREKLVRWYVELRKESERRSTIPITARQLESVIR 282
|
330 340
....*....|....*....|....*....
gi 6319448 816 IAESFAKMRLSEFVSSYDLDRAIKVVVDS 844
Cdd:cd17706 283 LAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
480-703 |
1.33e-141 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 418.47 E-value: 1.33e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 480 EEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKT 559
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 560 AHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTT 639
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6319448 640 LQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSH 703
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
496-839 |
2.74e-127 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 385.20 E-value: 2.74e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 496 KIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVG 575
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 576 LTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGG 655
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 656 RYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSHPENDEDRegeelkNNGEsaieqgedein 735
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQSQE------NEGE----------- 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 736 eqlnarqrrlqrqrkkeeeispIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLR-------RESISTGSFPITVR 808
Cdd:cd17756 224 ----------------------IPISKLKRYIAYCRAKCAPRLSEEAAEKLSNHYVTIRkdvrqneLESDNRSSIPITVR 281
|
330 340 350
....*....|....*....|....*....|.
gi 6319448 809 HLESILRIAESFAKMRLSEFVSSYDLDRAIK 839
Cdd:cd17756 282 QLEAIIRISESLAKMELSPIATEKHVEEAIR 312
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
495-840 |
4.19e-122 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 371.40 E-value: 4.19e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 495 DKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAV 574
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 575 GLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNG 654
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 655 GRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSHPENDEDregeelknngesaieqgedei 734
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGEMREIKP--------------------- 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 735 neqlnarqrrlqrqrkkeeEISPipqELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGS-FPITVRHLESI 813
Cdd:cd17761 220 -------------------EIDP---DLLRKYIAYARKNVRPVLTEEAKQLIKDFYVEMRKSGQETPSpVPITARQLEAL 277
|
330 340
....*....|....*....|....*..
gi 6319448 814 LRIAESFAKMRLSEFVSSYDLDRAIKV 840
Cdd:cd17761 278 VRLSEASARMRLSQEVTLEDAERAIRI 304
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
496-829 |
2.64e-114 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 350.90 E-value: 2.64e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 496 KIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVG 575
Cdd:cd17757 1 NLVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 576 LTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGG 655
Cdd:cd17757 81 LTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 656 RYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRShpendedregeelknngesaieqgEDEIN 735
Cdd:cd17757 161 RYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKR------------------------EEAIE 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 736 eqlnarqrrlqrqrkkeeeiSPIPQELLMKYIHYARTkIYPKLHQMDMDKVSRVYADLRRESISTG---SFPITVRHLES 812
Cdd:cd17757 217 --------------------PPFTAEQLKRYIAYART-FKPKLTKEAKDELVEQYKELRQDDASGStrsSYRITVRQLES 275
|
330
....*....|....*..
gi 6319448 813 ILRIAESFAKMRLSEFV 829
Cdd:cd17757 276 LIRLSEAIARLHCSDEV 292
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
496-841 |
1.51e-109 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 338.61 E-value: 1.51e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 496 KIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKhSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVG 575
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKRGDGM-KIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 576 LTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGG 655
Cdd:cd17758 80 LTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 656 RYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVvdSHVRSHpendedregeelknngesaieqgedeiN 735
Cdd:cd17758 160 RYNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHV--TYVHQH---------------------------N 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 736 EQLNArqrrlqrqrkkeeEISPIPQELLMKYIHYARTKiYPKLHQMDMDKVSRVYADLRRESISTGSFP-ITVRHLESIL 814
Cdd:cd17758 211 KQPDS-------------DFEPLDPKLLRAYIALAKRK-RPTVPPALADYIVQAYVEMRQEAKRSKDFTfTTPRTLLAIL 276
|
330 340
....*....|....*....|....*..
gi 6319448 815 RIAESFAKMRLSEFVSSYDLDRAIKVV 841
Cdd:cd17758 277 RLSQALARLRLSDSVEIDDVEEALRLM 303
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
496-841 |
1.93e-108 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 335.95 E-value: 1.93e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 496 KIISSMAPSIYGHRDIKTAVACSLFGGVPKNV-NGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAV 574
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFtKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 575 GLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNG 654
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 655 GRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSHPendedregeelknngesaiEQGEDEI 734
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTP-------------------EHIQDEV 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 735 neqlnarqrrlqrqrkkeeeispIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESIS-TGSFPITVRHLESI 813
Cdd:cd17755 222 -----------------------LDVEVLTDYISYAREHIHPKLSEEAAQELVQAYVDMRKMGSDaRKRITATPRQLESL 278
|
330 340
....*....|....*....|....*...
gi 6319448 814 LRIAESFAKMRLSEFVSSYDLDRAIKVV 841
Cdd:cd17755 279 IRLAEAHAKMRLSNVVEAEDVEEAVRLI 306
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
500-841 |
4.38e-100 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 313.63 E-value: 4.38e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 500 SMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTAS 579
Cdd:cd17754 5 SLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGLTAA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 580 VRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNS 659
Cdd:cd17754 85 VTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYGRYDV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 660 TLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVvdshVRSHPENdedregeelknngesaieqgedeineqln 739
Cdd:cd17754 165 YKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHV----LRMHRYI----------------------------- 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 740 arqrrlqrqrkkeeeispipqELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRR----ESISTGSFPITVRHLESILR 815
Cdd:cd17754 212 ---------------------KFLRKYIHYAKERIKPKLTQEAAEYIAEEYADLRNddntKTDKARTSPITARTLETLIR 270
|
330 340
....*....|....*....|....*.
gi 6319448 816 IAESFAKMRLSEFVSSYDLDRAIKVV 841
Cdd:cd17754 271 LATAHAKARLSKTVDKVDAEVALNLL 296
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
255-841 |
3.30e-87 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 297.29 E-value: 3.30e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 255 ILALFLAKCPEEMLKIFDLVAMEATELHYPDYARIHSEIH--VRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFP 332
Cdd:PTZ00111 165 LLVTFPADCIAELDKVLVKLFNELLSKHYSDLSLENNSFFprARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQTWIVP 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 333 QLKYVKFNCLKCGSILGPFFQDSNEEI----------RISFCTNCKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRL 402
Cdd:PTZ00111 245 EITMACFRCRGQKKIGLNDYQPCTCEHyeyviqgevnEPLLCNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDK 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 403 P-----------------RHREVI---LLADLVDVSKPGEEVEVTGIYK------NNYDGNLNAKngFPVFATIIEANSI 456
Cdd:PTZ00111 325 DgldnsvdnsglngeiymKDNEVInlnLYDDLIDSVKTGDRVTVVGILKvtpirtSTTRRTLKSL--YTYFVNVIHVKVI 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 457 KRREGNTANEGEEGL-DVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSI-- 533
Cdd:PTZ00111 403 NSTNANQPEKGLKYLgNENDFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGNKNSSDFNKSPda 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 534 -------RGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVR-KDPITKEWTLEGGALVLADKGVCL 605
Cdd:PTZ00111 483 cykvdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIKfNESDNGRAMIQPGAVVLANGGVCC 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 606 IDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRD 685
Cdd:PTZ00111 563 IDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLD 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 686 LVDEEADERLATFVVDSHVRSH---PENDEDREGEELKNNGESAIEQGEDEINEQlnarqrrlqrqrkkeeeispiPQEL 762
Cdd:PTZ00111 643 HIDQDTDQLISLSIAKDFLLPHmtgSGNDEDTYDRSNTMHVEDESLRSEKDYNKN---------------------DLDM 701
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 763 LMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESIST----------------------GSFPITV--RHLESILRIAE 818
Cdd:PTZ00111 702 LRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNFQTsnldelehaqedddddlyyqssGTRMIYVssRMISSIIRISV 781
|
650 660
....*....|....*....|...
gi 6319448 819 SFAKMRLSEFVSSYDLDRAIKVV 841
Cdd:PTZ00111 782 SLARMRLSTVVTPADALQAVQIV 804
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
497-844 |
2.76e-72 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 239.36 E-value: 2.76e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 497 IISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGK--HSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAV 574
Cdd:cd17759 2 IVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKnrIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTTS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 575 GLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQdRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNG 654
Cdd:cd17759 82 GLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGSQ-HQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPVG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 655 GRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLAtfvvdshvrSHPendedregeelknngesaieqgedei 734
Cdd:cd17759 161 GHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLS---------EHH-------------------------- 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 735 neqlnarqrrlqrqrkkeeeispipqELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGSFPITVRHLESIL 814
Cdd:cd17759 206 --------------------------QLLRKYISYARQYVNPVLSKDASEALQEFYLELRKQNQLADSSPITTRQLESLI 259
|
330 340 350
....*....|....*....|....*....|
gi 6319448 815 RIAESFAKMRLSEFVSSYDLDRAIKVVVDS 844
Cdd:cd17759 260 RLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
497-841 |
5.74e-69 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 230.90 E-value: 5.74e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 497 IISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGL 576
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 577 TASVRKDpiTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNgGR 656
Cdd:cd17760 82 TVTAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 657 YNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVvdshvrshpendedregeeLKNNGESaieqgedeine 736
Cdd:cd17760 159 YDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFI-------------------LENKGEP----------- 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 737 qlnarqrrlqrqrKKEEEISPIpqELLMKYIHYARtKIYPKLHQmDMDKVSRVYADLRRESISTGSFPITVRHLESILRI 816
Cdd:cd17760 209 -------------SKSSKLWSM--EKMRTYFCLIK-NLRPVLSD-EANAILLRYYQLQRQSDCRNAARTTIRMLESLIRL 271
|
330 340
....*....|....*....|....*
gi 6319448 817 AESFAKMRLSEFVSSYDLDRAIKVV 841
Cdd:cd17760 272 AEAHARLMFRETVTEEDAITVVSVM 296
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
305-434 |
2.21e-47 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 164.58 E-value: 2.21e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 305 SLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGpffqdsneeIRI---SFCTN--CKSKGPFRVNGEK 379
Cdd:pfam17207 1 SIRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVG---------VKItepTKCPNpeCGNKDPFKLVHEK 71
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 6319448 380 TVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNY 434
Cdd:pfam17207 72 SKFVDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
761-845 |
4.26e-32 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 119.57 E-value: 4.26e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 761 ELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESI-STGSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIK 839
Cdd:pfam17855 1 ELLRKYIAYAREKIKPKLSEEAREKLVDAYVELRKESTgSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAIR 80
|
....*.
gi 6319448 840 VVVDSF 845
Cdd:pfam17855 81 LLKESL 86
|
|
| MCM2_N |
pfam12619 |
Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is ... |
49-193 |
7.54e-24 |
|
Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is typically between 138 and 153 amino acids in length. The family is found in association with pfam00493. Mini-chromosome maintenance (MCM) proteins are essential for DNA replication. These proteins use ATPase activity to perform this function.
Pssm-ID: 403724 Cd Length: 148 Bit Score: 98.25 E-value: 7.54e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 49 EGDDNEVD--DVPDIDEVEEQMNEVDLMDDNMYEDYAADHNRDRYDPDQVDDR-EQQELSLSERRRIDAQLNERDRLLRN 125
Cdd:pfam12619 1 EDEEAEIDenDIDDLDPDEEEEDGEDLFGDNMEDDYRQNPELDRYDLDDIDDEgDYEEMDAAERRRAEAQLNRRDRELGA 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6319448 126 V------AYIDDEDEEQEGaaqLDEMGLPVQRRRRRRQYEDLENsdddLLSDMDIDPLREELTLESLSNVKANS 193
Cdd:pfam12619 81 ArrrrpaAFLQDDDDEDDL---DGDYGLPIQRRRRRRHYDEDQD----EDMDEDIDPFEEELSLESLADVKADS 147
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
209-299 |
2.30e-16 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 75.02 E-value: 2.30e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 209 RELKSFLLEYT-DETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAME--ATELHYPD 285
Cdd:pfam14551 2 RKFKDFLEEFReDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEvvKELSEDPD 81
|
90
....*....|....
gi 6319448 286 YARIHSEIHVRISD 299
Cdd:pfam14551 82 YAEEEKEFQVRFYN 95
|
|
| PRK09862 |
PRK09862 |
ATP-dependent protease; |
535-679 |
5.06e-05 |
|
ATP-dependent protease;
Pssm-ID: 182120 [Multi-domain] Cd Length: 506 Bit Score: 46.90 E-value: 5.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 535 GDINVLLLGDPGTAKSQI----------LKYVEKTAHRAVFATGQGAS---------------AVGLTASVRKDPITkew 589
Cdd:PRK09862 209 GGHNLLLIGPPGTGKTMLasringllpdLSNEEALESAAILSLVNAESvqkqwrqrpfrsphhSASLTAMVGGGAIP--- 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 590 tlEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPN-----GGRYNSTLP-- 662
Cdd:PRK09862 286 --GPGEISLAHNGVLFLDELPEFERRTLDALREPIESGQIHLSRTRAKITYPARFQLVAAMNPSptghyQGNHNRCTPeq 363
|
170
....*....|....*...
gi 6319448 663 -LAQNVSLTEPILSRFDI 679
Cdd:PRK09862 364 tLRYLNRLSGPFLDRFDL 381
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
538-677 |
1.40e-04 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 42.66 E-value: 1.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 538 NVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVG---LTASVRKDPITKEWTLegGALVLADK--GVCLIDEFDKM 612
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVFYVQLTRDTTeedLFGRRNIDPGGASWVD--GPLVRAARegEIAVLDEINRA 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6319448 613 NDQDRTSIHEAMEQQSISISKAG-IVTTLQARCSIIAAANPNGGRYNstlplaqnvSLTEPILSRF 677
Cdd:pfam07728 79 NPDVLNSLLSLLDERRLLLPDGGeLVKAAPDGFRLIATMNPLDRGLN---------ELSPALRSRF 135
|
|
| Mg_chelatase |
pfam01078 |
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ... |
538-679 |
5.76e-04 |
|
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.
Pssm-ID: 426032 [Multi-domain] Cd Length: 207 Bit Score: 42.14 E-value: 5.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 538 NVLLLGDPGTAKSQILKYV-------------EKTAHRAVfaTGQG-----------------ASAVGLT---ASVRKdp 584
Cdd:pfam01078 24 NLLMIGPPGSGKTMLAKRLpgilpplteaealEVTAIHSV--AGLGgdgglirrrpfraphhsASAAALVgggSIPRP-- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 585 itkewtlegGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANP----NGG----- 655
Cdd:pfam01078 100 ---------GEISLAHNGVLFLDELPEFKRRVLESLRQPLEDGEITISRARAKVTFPARFQLVAAMNPcpcgYLGdpnkr 170
|
170 180 190
....*....|....*....|....*....|...
gi 6319448 656 ---------RYNStlplaqnvSLTEPILSRFDI 679
Cdd:pfam01078 171 crcsprqirRYLS--------RLSGPLLDRIDL 195
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
538-684 |
9.47e-04 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 40.59 E-value: 9.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 538 NVLLLGDPGTAKSQILKYVEKTAHRA---VFATGqgASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMND 614
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFRPgapFLYLN--ASDLLEGLVVAELFGHFLVRLLFELAEKAKPGVLFIDEIDSLSR 98
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 615 QDRTSIHEAMEQQSISIskagivtTLQARCSIIAAANPNGGRynstlplaqnvSLTEPILSRFDILCVVR 684
Cdd:cd00009 99 GAQNALLRVLETLNDLR-------IDRENVRVIGATNRPLLG-----------DLDRALYDRLDIRIVIP 150
|
|
| RecA-like_ATAD1 |
cd19520 |
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ... |
539-651 |
1.32e-03 |
|
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase) is an ATPase that plays a critical role in regulating the surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, thereby regulating synaptic plasticity, learning and memory. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410928 [Multi-domain] Cd Length: 166 Bit Score: 40.49 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 539 VLLLGDPGTAKSQILKYVEKTAhravfatgqGASAVGLTASVrkdpITKEWTLEGGALV-----LADK---GVCLIDEFD 610
Cdd:cd19520 38 VLLYGPPGCGKTMLAKATAKEA---------GARFINLQVSS----LTDKWYGESQKLVaavfsLASKlqpSIIFIDEID 104
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 6319448 611 KMNDQDRTSIHEAMEQQsisisKA-------GIVTTLQARCSIIAAAN 651
Cdd:cd19520 105 SFLRQRSSTDHEATAMM-----KAefmslwdGLSTDGNCRVIVMGATN 147
|
|
| Spt5_N |
pfam11942 |
Spt5 transcription elongation factor, acidic N-terminal; This is the very acidic N-terminal ... |
51-137 |
5.27e-03 |
|
Spt5 transcription elongation factor, acidic N-terminal; This is the very acidic N-terminal region of the early transcription elongation factor Spt5. The Spt5-Spt4 complex regulates early transcription elongation by RNA polymerase II and has an imputed role in pre-mRNA processing via its physical association with mRNA capping enzymes. The actual function of this N-terminal domain is not known although it is dispensable for binding to Spt4.
Pssm-ID: 463406 Cd Length: 97 Bit Score: 37.25 E-value: 5.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319448 51 DDNEVDDVPDIDEVEEQMNEV--DLMDDNMYEDYAADHNRDRYDPDQVDDREQQELSLSErRRIDAQLNERDRLLRNVAY 128
Cdd:pfam11942 4 DEAEVDDDEEEEEDEDEDEDGadDFIEDDEEDEDEEDGRRDDRRHRELDRRRELEEDEDA-EEIAEYLKERYGRSSSDAY 82
|
....*....
gi 6319448 129 IDDEDEEQE 137
Cdd:pfam11942 83 RGDAEEGVP 91
|
|
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