NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|6319785|ref|NP_009866|]
View 

homeodomain mating type protein alpha2 [Saccharomyces cerevisiae S288C]

Protein Classification

homeobox domain-containing protein( domain architecture ID 10647766)

homeobox domain-containing protein may be involved in the transcriptional regulation of key eukaryotic developmental processes

CATH:  1.10.10.60
Gene Ontology:  GO:0003677
PubMed:  21557080|26464018|27768937|1357790
SCOP:  4000291

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 135-188 1.51e-12

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


:

Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 59.96  E-value: 1.51e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 6319785     135 RFTKENVRILESWFAKNienPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEK 188
Cdd:smart00389   7 SFTPEQLEELEKEFQKN---PYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
 
Name Accession Description Interval E-value
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 135-188 1.51e-12

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 59.96  E-value: 1.51e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 6319785     135 RFTKENVRILESWFAKNienPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEK 188
Cdd:smart00389   7 SFTPEQLEELEKEFQKN---PYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 132-188 4.39e-11

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 56.10  E-value: 4.39e-11
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 6319785  132 RGHRFTKENVRILESWFAKNienPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEK 188
Cdd:cd00086   3 KRTRFTPEQLEELEKEFEKN---PYPSREEREELAKELGLTERQVKIWFQNRRAKLK 56
Homeodomain pfam00046
Homeodomain;
134-188 5.05e-07

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 45.18  E-value: 5.05e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 6319785    134 HRFTKENVRILESWFAKNienPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEK 188
Cdd:pfam00046   5 TTFTPEQLEELEKEFQEN---PYPSAEEREELAAQLGLTERQVKVWFQNRRAKWK 56
 
Name Accession Description Interval E-value
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 135-188 1.51e-12

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 59.96  E-value: 1.51e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 6319785     135 RFTKENVRILESWFAKNienPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEK 188
Cdd:smart00389   7 SFTPEQLEELEKEFQKN---PYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 132-188 4.39e-11

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 56.10  E-value: 4.39e-11
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 6319785  132 RGHRFTKENVRILESWFAKNienPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEK 188
Cdd:cd00086   3 KRTRFTPEQLEELEKEFEKN---PYPSREEREELAKELGLTERQVKIWFQNRRAKLK 56
Homeodomain pfam00046
Homeodomain;
134-188 5.05e-07

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 45.18  E-value: 5.05e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 6319785    134 HRFTKENVRILESWFAKNienPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEK 188
Cdd:pfam00046   5 TTFTPEQLEELEKEFQEN---PYPSAEEREELAAQLGLTERQVKVWFQNRRAKWK 56
Homeobox_KN pfam05920
Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to ...
 148-185 3.99e-03

Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to human and plants. They were first identified as TALE homeobox genes in eukaryotes, (including KNOX and MEIS genes). They have been recently classified.


Pssm-ID: 428673  Cd Length: 39  Bit Score: 34.03  E-value: 3.99e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 6319785    148 FAKNIENPYLDTKGLENLMKNTSLSRIQIKNWVSNRRR 185
Cdd:pfam05920   1 LYEHLHNPYPSEEEKAELAKETGLSRKQISNWFINARR 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH