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Conserved domains on  [gi|6319991|ref|NP_010071|]
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Uga4p [Saccharomyces cerevisiae S288C]

Protein Classification

APC family permease( domain architecture ID 1903533)

APC (amino acid/polyamine/organocation) family permease is involved in the uptake of a specific amino acid and/or polyamine substrate with the concomitant import of a proton

Gene Ontology:  GO:0055085|GO:0022857
TCDB:  2.A.3

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
AA_permease_2 super family cl45918
Amino acid permease;
61-529 4.71e-86

Amino acid permease;


The actual alignment was detected with superfamily member TIGR00907:

Pssm-ID: 459263 [Multi-domain]  Cd Length: 482  Bit Score: 275.47  E-value: 4.71e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991     61 LAEIGYKQELKRQFSTLQVFGIAFSIMGLLPSIASVMGGGLGGG-PATLVWGWFVAAFFILLVGITMAEHASSIPTAGGL 139
Cdd:TIGR00907   1 LVALGYKPELKREFSLWSIFGFAFSISNSWTGISTTYNYGLSSGgAMSIVWGWIIAGAGSICIALSLAELSSAYPTSGGQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    140 YYWTYYYAPEGYKEIISFIIGCSNSLALAAGVCSIDYGLAEEIAAAVTLTKDGN-FEVTSGKLYGIFAGAVVVMCICTCV 218
Cdd:TIGR00907  81 YFWSAKLAPPRQMPFASWMTGWFNLAGQVAGTASTDLSVAQLILGIVSLTTPGReYIPTRWHIFGIMIGIHLIHALINSL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    219 ASGAIARLQTLSIFANLFIIVLLFIALPIGTKHRmggFNDGDFIFGKYENLSD--WNNGWQFCLAGFMPAvWTIGSFDSC 296
Cdd:TIGR00907 161 PTKWLPRITSSAAYWSLLGFLTICITLLACKSPK---FNDGKFVFTNFNNSTGgwKPGGFAFLLGLLNPA-WSMTGYDGT 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    297 VHQSEEAKDAKKSVPIGIISSIAVCWILGWLIIICLMACINpDIDSVLDSKYGFALAQIIYDSLGKKW-AIAFMSLIAFC 375
Cdd:TIGR00907 237 AHMAEEIENPEVVGPRAIIGAVAIGIVTGFCFNIVLFFSMG-DIDSLISSTTGQPIAQIFYNALGNKAgAIFLLCLILVT 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    376 QFLMGASITTAVSRQVWAFSRDNGLPLSKYIKRVDSKYSVPFFAILAACVGSLILGLLCLIDDAATDALFSLAVAGNNLA 455
Cdd:TIGR00907 316 SFFCAITCMTANSRMIYAFSRDGGLPFSPLWSRVNPRTQVPLNAVWLSAVWIILIGLLGLGSSTAFQAIFSVCTVALDVS 395
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6319991    456 WSTPTVFRLTSGRDLFRPGPFYLGKiWSPIVAWTGVAFQLFIIILVMFPSqQHGITKSTMNYACVIGPGIWILA 529
Cdd:TIGR00907 396 YVIPIICKLAKGRNTIAPGPFWLGK-YGFFVNAVAVAWTVFSSVLFSFPP-VLPVTPENMNYAVVVFAGVLAIS 467
 
Name Accession Description Interval E-value
2A0304 TIGR00907
amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides ...
61-529 4.71e-86

amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273331 [Multi-domain]  Cd Length: 482  Bit Score: 275.47  E-value: 4.71e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991     61 LAEIGYKQELKRQFSTLQVFGIAFSIMGLLPSIASVMGGGLGGG-PATLVWGWFVAAFFILLVGITMAEHASSIPTAGGL 139
Cdd:TIGR00907   1 LVALGYKPELKREFSLWSIFGFAFSISNSWTGISTTYNYGLSSGgAMSIVWGWIIAGAGSICIALSLAELSSAYPTSGGQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    140 YYWTYYYAPEGYKEIISFIIGCSNSLALAAGVCSIDYGLAEEIAAAVTLTKDGN-FEVTSGKLYGIFAGAVVVMCICTCV 218
Cdd:TIGR00907  81 YFWSAKLAPPRQMPFASWMTGWFNLAGQVAGTASTDLSVAQLILGIVSLTTPGReYIPTRWHIFGIMIGIHLIHALINSL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    219 ASGAIARLQTLSIFANLFIIVLLFIALPIGTKHRmggFNDGDFIFGKYENLSD--WNNGWQFCLAGFMPAvWTIGSFDSC 296
Cdd:TIGR00907 161 PTKWLPRITSSAAYWSLLGFLTICITLLACKSPK---FNDGKFVFTNFNNSTGgwKPGGFAFLLGLLNPA-WSMTGYDGT 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    297 VHQSEEAKDAKKSVPIGIISSIAVCWILGWLIIICLMACINpDIDSVLDSKYGFALAQIIYDSLGKKW-AIAFMSLIAFC 375
Cdd:TIGR00907 237 AHMAEEIENPEVVGPRAIIGAVAIGIVTGFCFNIVLFFSMG-DIDSLISSTTGQPIAQIFYNALGNKAgAIFLLCLILVT 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    376 QFLMGASITTAVSRQVWAFSRDNGLPLSKYIKRVDSKYSVPFFAILAACVGSLILGLLCLIDDAATDALFSLAVAGNNLA 455
Cdd:TIGR00907 316 SFFCAITCMTANSRMIYAFSRDGGLPFSPLWSRVNPRTQVPLNAVWLSAVWIILIGLLGLGSSTAFQAIFSVCTVALDVS 395
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6319991    456 WSTPTVFRLTSGRDLFRPGPFYLGKiWSPIVAWTGVAFQLFIIILVMFPSqQHGITKSTMNYACVIGPGIWILA 529
Cdd:TIGR00907 396 YVIPIICKLAKGRNTIAPGPFWLGK-YGFFVNAVAVAWTVFSSVLFSFPP-VLPVTPENMNYAVVVFAGVLAIS 467
AA_permease_2 pfam13520
Amino acid permease;
74-521 1.31e-56

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 195.99  E-value: 1.31e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991     74 FSTLQVFGIAFSIMGLLPSIASvmGGGLGGGPATLVWGWFVAAFFILLVGITMAEHASSIPTAGGLYYWTYYyapeGYKE 153
Cdd:pfam13520   1 LGLLSAFALVIGSVIGSGIFVA--PLVASGGPALIVWGWIAAIIFSLAVGLVYAELSSALPRSGGIYVYLEN----AFGK 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    154 IISFIIGCSNSLALAAGVCSIDYGLAEEIAAAVtltkDGNFEVTSGKLYGIFAGAVVVMCICTCVASGAIARLQTLSIFA 233
Cdd:pfam13520  75 FVAFLAGWSNWFAYVLGLASSASVAASYLLSAL----GPDLVPTTWLTYGIAIAILIIFAIINIRGVRESAKIQNILGIL 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    234 NLFIIVLLFIALPIGTKHRmGGFNDGDFIFGkyenlSDWNNGWQFCLAGFMPAVWTIGSFDSCVHQSEEAKdaKKSVPIG 313
Cdd:pfam13520 151 KLLLPLILIIILGLVTADG-GGFNLLSGEWH-----TFFPDGWPGVFAGFLGVLWSFTGFESAANVSEEVK--KRNVPKA 222
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    314 IISSIAVCWILGWLIIICLMACINPDIDSVLDSKYGFAlaQIIYDSLGKKW-AIAFMSLIAFCQFLMGASITTAVSRQVW 392
Cdd:pfam13520 223 IFIGVIIVGVLYILVNIAFFGVVPDDEIALSSGLGQVA--ALLFQAVGGKWgAIIVVILLALSLLGAVNTAIVGASRLLY 300
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    393 AFSRDNGLPLSKYIKRVDsKYSVPFFAILAACVGSLILGLLCLIDDAATDALFSLAVAGNNLAWSTPTVFRLtsgrdLFR 472
Cdd:pfam13520 301 ALARDGVLPFSRFFAKVN-KFGSPIRAIILTAILSLILLLLFLLSPAAYNALLSLSAYGYLLSYLLPIIGLL-----ILR 374
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 6319991    473 PGPFYLGKIW-SPIVAWTGVAFQLFIIILVMFPSQQHgITKSTMNYACVI 521
Cdd:pfam13520 375 KKRPDLGRIPgRWPVAIFGILFSLFLIVALFFPPVGP-ATGSSLNYAIIL 423
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
65-531 4.78e-32

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 128.48  E-value: 4.78e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991   65 GYKQELKRQFSTLQVFGIAFSIMglLPS-IASVMGGGLGGGPATLVWGWFVAAFFILLVGITMAEHASSIPTAGGLYYWT 143
Cdd:COG0531   4 GESSELKRKLGLFDLVALGVGAI--IGAgIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYA 81
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991  144 YyyapEGYKEIISFIIGCSNSLALAAGVCSIDYGLAEEIAAAVTLtkdgnfevtsGKLYGIFAGAVVVMCICTCVASGAI 223
Cdd:COG0531  82 R----RALGPLLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPA----------GGSVLIALVLILLLTLLNLRGVKES 147
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991  224 ARLQTLSIFANLFIIVLLFIALpigtkhrmggfndgdFIFGKYENLSDWN---NGWQFCLAGFMPAVWTIGSFDSCVHQS 300
Cdd:COG0531 148 AKVNNILTVLKLLVLLLFIVVG---------------LFAFDPANFTPFLpagGGLSGVLAALALAFFAFTGFEAIANLA 212
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991  301 EEAKDAKKSVPIGIISSIAVCWILGWLIIICLMACINPDIDSVLDSkygfALAQIIYDSLGKKWAIAFMSLIAFCQFLMG 380
Cdd:COG0531 213 EEAKNPKRNIPRAIILSLLIVGVLYILVSLALTGVVPYDELAASGA----PLADAAEAVFGPWGAILIALGALLSLLGAL 288
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991  381 ASITTAVSRQVWAFSRDNGLPlsKYIKRVDSKYSVPFFAILAACVGSLIlglLCLIDDAATDALFSLAVAGNNLA--WST 458
Cdd:COG0531 289 NASILGASRLLYAMARDGLLP--KVFAKVHPRFGTPVNAILLTGVIALL---LLLLGAASFTALASLASVGVLLAylLVA 363
                       410       420       430       440       450       460       470
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6319991  459 PTVFRLtSGRDLFRPGPFylgKIWSPIVAWTGVAFQLFIIILVMFPSqqhgitkstmnyacVIGPGIWILAGI 531
Cdd:COG0531 364 LAVIVL-RRRRPDLPRPF---RVPLPLIPILGILLCLFLLYLLGPGA--------------LLIGLVLLAIGL 418
 
Name Accession Description Interval E-value
2A0304 TIGR00907
amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides ...
61-529 4.71e-86

amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273331 [Multi-domain]  Cd Length: 482  Bit Score: 275.47  E-value: 4.71e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991     61 LAEIGYKQELKRQFSTLQVFGIAFSIMGLLPSIASVMGGGLGGG-PATLVWGWFVAAFFILLVGITMAEHASSIPTAGGL 139
Cdd:TIGR00907   1 LVALGYKPELKREFSLWSIFGFAFSISNSWTGISTTYNYGLSSGgAMSIVWGWIIAGAGSICIALSLAELSSAYPTSGGQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    140 YYWTYYYAPEGYKEIISFIIGCSNSLALAAGVCSIDYGLAEEIAAAVTLTKDGN-FEVTSGKLYGIFAGAVVVMCICTCV 218
Cdd:TIGR00907  81 YFWSAKLAPPRQMPFASWMTGWFNLAGQVAGTASTDLSVAQLILGIVSLTTPGReYIPTRWHIFGIMIGIHLIHALINSL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    219 ASGAIARLQTLSIFANLFIIVLLFIALPIGTKHRmggFNDGDFIFGKYENLSD--WNNGWQFCLAGFMPAvWTIGSFDSC 296
Cdd:TIGR00907 161 PTKWLPRITSSAAYWSLLGFLTICITLLACKSPK---FNDGKFVFTNFNNSTGgwKPGGFAFLLGLLNPA-WSMTGYDGT 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    297 VHQSEEAKDAKKSVPIGIISSIAVCWILGWLIIICLMACINpDIDSVLDSKYGFALAQIIYDSLGKKW-AIAFMSLIAFC 375
Cdd:TIGR00907 237 AHMAEEIENPEVVGPRAIIGAVAIGIVTGFCFNIVLFFSMG-DIDSLISSTTGQPIAQIFYNALGNKAgAIFLLCLILVT 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    376 QFLMGASITTAVSRQVWAFSRDNGLPLSKYIKRVDSKYSVPFFAILAACVGSLILGLLCLIDDAATDALFSLAVAGNNLA 455
Cdd:TIGR00907 316 SFFCAITCMTANSRMIYAFSRDGGLPFSPLWSRVNPRTQVPLNAVWLSAVWIILIGLLGLGSSTAFQAIFSVCTVALDVS 395
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6319991    456 WSTPTVFRLTSGRDLFRPGPFYLGKiWSPIVAWTGVAFQLFIIILVMFPSqQHGITKSTMNYACVIGPGIWILA 529
Cdd:TIGR00907 396 YVIPIICKLAKGRNTIAPGPFWLGK-YGFFVNAVAVAWTVFSSVLFSFPP-VLPVTPENMNYAVVVFAGVLAIS 467
AA_permease_2 pfam13520
Amino acid permease;
74-521 1.31e-56

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 195.99  E-value: 1.31e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991     74 FSTLQVFGIAFSIMGLLPSIASvmGGGLGGGPATLVWGWFVAAFFILLVGITMAEHASSIPTAGGLYYWTYYyapeGYKE 153
Cdd:pfam13520   1 LGLLSAFALVIGSVIGSGIFVA--PLVASGGPALIVWGWIAAIIFSLAVGLVYAELSSALPRSGGIYVYLEN----AFGK 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    154 IISFIIGCSNSLALAAGVCSIDYGLAEEIAAAVtltkDGNFEVTSGKLYGIFAGAVVVMCICTCVASGAIARLQTLSIFA 233
Cdd:pfam13520  75 FVAFLAGWSNWFAYVLGLASSASVAASYLLSAL----GPDLVPTTWLTYGIAIAILIIFAIINIRGVRESAKIQNILGIL 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    234 NLFIIVLLFIALPIGTKHRmGGFNDGDFIFGkyenlSDWNNGWQFCLAGFMPAVWTIGSFDSCVHQSEEAKdaKKSVPIG 313
Cdd:pfam13520 151 KLLLPLILIIILGLVTADG-GGFNLLSGEWH-----TFFPDGWPGVFAGFLGVLWSFTGFESAANVSEEVK--KRNVPKA 222
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    314 IISSIAVCWILGWLIIICLMACINPDIDSVLDSKYGFAlaQIIYDSLGKKW-AIAFMSLIAFCQFLMGASITTAVSRQVW 392
Cdd:pfam13520 223 IFIGVIIVGVLYILVNIAFFGVVPDDEIALSSGLGQVA--ALLFQAVGGKWgAIIVVILLALSLLGAVNTAIVGASRLLY 300
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    393 AFSRDNGLPLSKYIKRVDsKYSVPFFAILAACVGSLILGLLCLIDDAATDALFSLAVAGNNLAWSTPTVFRLtsgrdLFR 472
Cdd:pfam13520 301 ALARDGVLPFSRFFAKVN-KFGSPIRAIILTAILSLILLLLFLLSPAAYNALLSLSAYGYLLSYLLPIIGLL-----ILR 374
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 6319991    473 PGPFYLGKIW-SPIVAWTGVAFQLFIIILVMFPSQQHgITKSTMNYACVI 521
Cdd:pfam13520 375 KKRPDLGRIPgRWPVAIFGILFSLFLIVALFFPPVGP-ATGSSLNYAIIL 423
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
65-531 4.78e-32

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 128.48  E-value: 4.78e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991   65 GYKQELKRQFSTLQVFGIAFSIMglLPS-IASVMGGGLGGGPATLVWGWFVAAFFILLVGITMAEHASSIPTAGGLYYWT 143
Cdd:COG0531   4 GESSELKRKLGLFDLVALGVGAI--IGAgIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYA 81
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991  144 YyyapEGYKEIISFIIGCSNSLALAAGVCSIDYGLAEEIAAAVTLtkdgnfevtsGKLYGIFAGAVVVMCICTCVASGAI 223
Cdd:COG0531  82 R----RALGPLLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPA----------GGSVLIALVLILLLTLLNLRGVKES 147
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991  224 ARLQTLSIFANLFIIVLLFIALpigtkhrmggfndgdFIFGKYENLSDWN---NGWQFCLAGFMPAVWTIGSFDSCVHQS 300
Cdd:COG0531 148 AKVNNILTVLKLLVLLLFIVVG---------------LFAFDPANFTPFLpagGGLSGVLAALALAFFAFTGFEAIANLA 212
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991  301 EEAKDAKKSVPIGIISSIAVCWILGWLIIICLMACINPDIDSVLDSkygfALAQIIYDSLGKKWAIAFMSLIAFCQFLMG 380
Cdd:COG0531 213 EEAKNPKRNIPRAIILSLLIVGVLYILVSLALTGVVPYDELAASGA----PLADAAEAVFGPWGAILIALGALLSLLGAL 288
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991  381 ASITTAVSRQVWAFSRDNGLPlsKYIKRVDSKYSVPFFAILAACVGSLIlglLCLIDDAATDALFSLAVAGNNLA--WST 458
Cdd:COG0531 289 NASILGASRLLYAMARDGLLP--KVFAKVHPRFGTPVNAILLTGVIALL---LLLLGAASFTALASLASVGVLLAylLVA 363
                       410       420       430       440       450       460       470
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6319991  459 PTVFRLtSGRDLFRPGPFylgKIWSPIVAWTGVAFQLFIIILVMFPSqqhgitkstmnyacVIGPGIWILAGI 531
Cdd:COG0531 364 LAVIVL-RRRRPDLPRPF---RVPLPLIPILGILLCLFLLYLLGPGA--------------LLIGLVLLAIGL 418
AA_permease pfam00324
Amino acid permease;
105-518 3.30e-12

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 68.89  E-value: 3.30e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    105 PATLVWGWFVAAFFILLVGITMAEHASSIPTAGGlyywTYYYAPEGYKEIISFIIGcsnslaLAAGVCSIDYGLAEEIAA 184
Cdd:pfam00324  28 PAGALLGYLISGVVIFLVMLSLGEISTNGPVSGG----FYTYASRFLGPSLGFATG------WNYWLSWITVLALELTAA 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    185 AVTLTKDGNFEVTSgKLYGIFAGAVVVMCICTCVASGAIARLQTLSIFANLFIIVLLFIALPIGtkHRMGGFNDGDFIFG 264
Cdd:pfam00324  98 SILIQFWELVPDIP-YLWVWGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIIVGIIL--LSGGNPNDGAIFRY 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    265 KYENLSDWNNGWQFC---LAGFMPAVWTIGSFDSCVHQSEEAKDAKKSVPIGIISSIAVCWILGWLIIICLMACINPDID 341
Cdd:pfam00324 175 LGDNGGKNNFPPGFGkgfISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWNDP 254
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    342 SVL-DSKYGFALAQIIYDSLGKKWAIAFMSLIAFCQFLMGA-SITTAVSRQVWAFSRDNGLPlsKYIKRVDsKYSVPFFA 419
Cdd:pfam00324 255 GLLnDSASAASPFVIFFKFLGISGLAPLINAVILTAALSAAnSSLYSGSRMLYSLARDGLAP--KFLKKVD-KRGVPLRA 331
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    420 ILAACVGSLILGLLC-LIDDAATDALFSLAVAGNNLAWS----TPTVFRL---TSGRDLFRPGPFYLGKIWSPIVAWTgv 491
Cdd:pfam00324 332 ILVSMVISLLALLLAsLNPAIVFNFLLAISGLSGLIVWGlislSHLRFRKafkYQGRSIDELPFKAPLGPLGVILGLA-- 409
                         410       420
                  ....*....|....*....|....*..
gi 6319991    492 AFQLFIIILVMFPSQQHGITKSTMNYA 518
Cdd:pfam00324 410 AIIIILIIQFLYAFLPVPGGPKNWGAG 436
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
69-433 1.21e-11

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 67.15  E-value: 1.21e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991     69 ELKRQFSTLQVfgIAFSIMGLLPSIASVMGGGLGGGPA--TLVWGWFVAAFFILLVGITMAEHASSIPTAGGLYYWTYYy 146
Cdd:TIGR00906  25 KMKRCLTTWDL--MALGIGSTIGAGIYVLTGEVARNDSgpAIVLSFLISGLAAVLSGFCYAEFGARVPKAGSAYLYSYV- 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    147 apeGYKEIISFIIGCSNSLALAAGVCSIDYGLAEEIAAAVTlTKDGNFEVTSGKL-------YGIFAGAVVVMCICTCVA 219
Cdd:TIGR00906 102 ---TVGELWAFITGWNLILEYVIGTAAVARSWSAYFDELLN-KQIGQFRRTYFKLnydglaeYPDFFAVCLILLLAVLLS 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    220 SGAIARLQTLSIFANLFIIVLLFIALpigtkhrmGGFNDGDFifgkyenlSDWNNGWQFCLAGFMPAVWT---------- 289
Cdd:TIGR00906 178 FGVKESAWVNKIFTAINILVLLFVII--------AGFTKADV--------ANWSITEEKGAGGFMPYGFTgvlsgaatcf 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    290 ---IGsFDSCVHQSEEAKDAKKSVPIGIISSIAVCWILGWLI--IICLMA---CINPdidsvlDSKYGFALAQIIYDSlg 361
Cdd:TIGR00906 242 fafIG-FDAIATTGEEVKNPQRAIPIGIVTSLLVCFVAYFLMsaALTLMMpyyLLDP------DAPFPVAFEYVGWDP-- 312
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6319991    362 KKWAIAFMSLIAFCQFLMGASIttAVSRQVWAFSRDNGLPlsKYIKRVDSKYSVPFFAILAACVGSLILGLL 433
Cdd:TIGR00906 313 AKYIVAVGALCGMSTSLLGGMF--PLPRVIYAMARDGLLF--KWLAQINSKTKTPINATVVSGAIAALMAFL 380
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
113-472 5.48e-04

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 43.16  E-value: 5.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    113 FVAAFFILLVGITMaehaSSIPT-----AGGLYYwtyyyapegykeIISFIIGcsNSLALAAGVCsidYGLAEEIAAA-- 185
Cdd:TIGR00930 118 LLCCCVTTITGLSM----SAIATngvvkGGGAYY------------LISRSLG--PEFGGSIGLI---FAFANAVAVAmy 176
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    186 --------VTLTKDGNFEVTSGKLYGI-FAGAVVVMCICTCVASGaiarLQTLSIFANLFIIVLL--FIALPIGT----- 249
Cdd:TIGR00930 177 vvgfaetvLDLLRENGSKIMVDPINDIrIYGTVTVVVLLGISFAG----MEWENKAQVLFLVIVLlsILNIFVGTiipaf 252
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    250 -KHRMGGFNDGDFIFgKYENLSDWN--NGWQFCLAG-FMPAVWTI--GSfdscvHQSEEAKDAKKSVPIGIISSIAVCWI 323
Cdd:TIGR00930 253 dKPAKGFFGLGNEIF-SENFIPGIPgpEGGFFSLFGiFFPSVTGIlaGA-----NISGDLKDPQKAIPKGTLLAILTTTV 326
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    324 LGWLIIICLMACI--------NPDIDSVLDSKYGFALAQIIYDSLGKKWAIAFMSLI-AFCQFL--------MGASITTA 386
Cdd:TIGR00930 327 VYLGSVVLFGACVvrdatgdkNDTLVTNCTSAACFSECAHNTCSYGLMNNLQVMSLVsPFPPLItagifsatLSSALASL 406
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6319991    387 VS--RQVWAFSRDNGLPLSKYIKRVDSKYSVPFFAIL---AACVGSLILGLLCLIddAATDALFSLA-VAGNNLAWSTPT 460
Cdd:TIGR00930 407 VSapRLFQALCKDNIYPFLQFFGKGYGKNGEPLRAYLltaFIAEGFILIAELNTI--APIISNFFLAsYALINFSCFHAS 484
                         410
                  ....*....|..
gi 6319991    461 VFRLTSGRDLFR 472
Cdd:TIGR00930 485 LLRSPGWRPRFK 496
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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