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Conserved domains on  [gi|398366479|ref|NP_010603|]
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Him1p [Saccharomyces cerevisiae S288C]

Protein Classification

HIM1 domain-containing protein( domain architecture ID 10555287)

HIM1 domain-containing protein similar to Saccharomyces cerevisiae protein HIM1 (high induction of mutagenesis protein 1) that may participate in the control of processing of mutational intermediates appearing during error-prone bypass of DNA damage; belongs to the Rossmann-fold superfamily of NAD(P)(+)-binding proteins

PubMed:  15885712|30945211|25704928

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HIM1 pfam08732
HIM1; HIM1 (high induction of mutagenesis protein 1) plays a role in the control of ...
 168-336 1.66e-92

HIM1; HIM1 (high induction of mutagenesis protein 1) plays a role in the control of spontaneous and induced mutagenesis. It is thought to participate in the control of processing of mutational intermediates appearing during error-prone bypass of DNA damage.


:

Pssm-ID: 400878  Cd Length: 169  Bit Score: 275.74  E-value: 1.66e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366479  168 VTQLIIPRSETWPKLLPRIFSGTQKLEKFDIDNKNYVPGRSLPSLCDISTMVCSLGSTSARVRRTQVPSSFADYYLPFNL 247
Cdd:pfam08732   1 VIQLIIPDSTKWPDLLPRIFSGETKLEKGLIENENYVLGRKLPSLDDIKTMISTLGSTSHSAKKSNTPRNFVDYDLNFQL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366479  248 AQEFTNTTNKRLVVTTAFNNDFLSKTFEYFRIKAKLENDLDEALPNKLKELVILRPGPMCGQHGNPINVELGKENSTFLE 327
Cdd:pfam08732  81 AQTFANTEDKKLVIVTSFNNKLLSHVSPYFRTKMKLENDLQNKLPPKLKELVILRPGPLVGNHGNPINTSLNKRNSTLLE 160


                  ....*....
gi 398366479  328 KIFYYPHYL 336
Cdd:pfam08732 161 QAILYKKYL 169
 
Name Accession Description Interval E-value
HIM1 pfam08732
HIM1; HIM1 (high induction of mutagenesis protein 1) plays a role in the control of ...
 168-336 1.66e-92

HIM1; HIM1 (high induction of mutagenesis protein 1) plays a role in the control of spontaneous and induced mutagenesis. It is thought to participate in the control of processing of mutational intermediates appearing during error-prone bypass of DNA damage.


Pssm-ID: 400878  Cd Length: 169  Bit Score: 275.74  E-value: 1.66e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366479  168 VTQLIIPRSETWPKLLPRIFSGTQKLEKFDIDNKNYVPGRSLPSLCDISTMVCSLGSTSARVRRTQVPSSFADYYLPFNL 247
Cdd:pfam08732   1 VIQLIIPDSTKWPDLLPRIFSGETKLEKGLIENENYVLGRKLPSLDDIKTMISTLGSTSHSAKKSNTPRNFVDYDLNFQL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366479  248 AQEFTNTTNKRLVVTTAFNNDFLSKTFEYFRIKAKLENDLDEALPNKLKELVILRPGPMCGQHGNPINVELGKENSTFLE 327
Cdd:pfam08732  81 AQTFANTEDKKLVIVTSFNNKLLSHVSPYFRTKMKLENDLQNKLPPKLKELVILRPGPLVGNHGNPINTSLNKRNSTLLE 160


                  ....*....
gi 398366479  328 KIFYYPHYL 336
Cdd:pfam08732 161 QAILYKKYL 169
 
Name Accession Description Interval E-value
HIM1 pfam08732
HIM1; HIM1 (high induction of mutagenesis protein 1) plays a role in the control of ...
 168-336 1.66e-92

HIM1; HIM1 (high induction of mutagenesis protein 1) plays a role in the control of spontaneous and induced mutagenesis. It is thought to participate in the control of processing of mutational intermediates appearing during error-prone bypass of DNA damage.


Pssm-ID: 400878  Cd Length: 169  Bit Score: 275.74  E-value: 1.66e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366479  168 VTQLIIPRSETWPKLLPRIFSGTQKLEKFDIDNKNYVPGRSLPSLCDISTMVCSLGSTSARVRRTQVPSSFADYYLPFNL 247
Cdd:pfam08732   1 VIQLIIPDSTKWPDLLPRIFSGETKLEKGLIENENYVLGRKLPSLDDIKTMISTLGSTSHSAKKSNTPRNFVDYDLNFQL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366479  248 AQEFTNTTNKRLVVTTAFNNDFLSKTFEYFRIKAKLENDLDEALPNKLKELVILRPGPMCGQHGNPINVELGKENSTFLE 327
Cdd:pfam08732  81 AQTFANTEDKKLVIVTSFNNKLLSHVSPYFRTKMKLENDLQNKLPPKLKELVILRPGPLVGNHGNPINTSLNKRNSTLLE 160


                  ....*....
gi 398366479  328 KIFYYPHYL 336
Cdd:pfam08732 161 QAILYKKYL 169
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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