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Conserved domains on  [gi|398364577|ref|NP_011012|]
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Dot6p [Saccharomyces cerevisiae S288C]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 10446569)

SANT/Myb domain-containing protein binds DNA and may function as a transcription factor

CATH:  1.10.10.60
Gene Ontology:  GO:0006355|GO:0003700|GO:0003677
PubMed:  1631139|8882580

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 75-117 3.99e-09

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


:

Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 52.51  E-value: 3.99e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 398364577   75 WDPQDDLLLRHLkeVKKMG--WKDISQYFPNRTPNACQFRWRRLK 117
Cdd:pfam00249   4 WTPEEDELLLEA--VEKLGnrWKKIAKLLPGRTDNQCKNRWQNYL 46
 
Name Accession Description Interval E-value
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 75-117 3.99e-09

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 52.51  E-value: 3.99e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 398364577   75 WDPQDDLLLRHLkeVKKMG--WKDISQYFPNRTPNACQFRWRRLK 117
Cdd:pfam00249   4 WTPEEDELLLEA--VEKLGnrWKKIAKLLPGRTDNQCKNRWQNYL 46
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
75-118 6.24e-09

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 52.23  E-value: 6.24e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 398364577    75 WDPQDDLLLRHLkeVKKMG---WKDISQYFPNRTPNACQFRWRRLKS 118
Cdd:smart00717   4 WTEEEDELLIEL--VKKYGknnWEKIAKELPGRTAEQCRERWRNLLK 48
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 75-117 9.40e-09

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 51.42  E-value: 9.40e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 398364577  75 WDPQDDLLLRHLkeVKKMG---WKDISQYFPNRTPNACQFRWRRLK 117
Cdd:cd00167    2 WTEEEDELLLEA--VKKYGknnWEKIAKELPGRTPKQCRERWRNLL 45
 
Name Accession Description Interval E-value
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 75-117 3.99e-09

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 52.51  E-value: 3.99e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 398364577   75 WDPQDDLLLRHLkeVKKMG--WKDISQYFPNRTPNACQFRWRRLK 117
Cdd:pfam00249   4 WTPEEDELLLEA--VEKLGnrWKKIAKLLPGRTDNQCKNRWQNYL 46
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 75-125 4.93e-09

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 52.70  E-value: 4.93e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 398364577   75 WDPQDDLLLRHLKEVKKMGWKDISQYFPNRTPNACQFRWRRLKSGNLKSNK 125
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCFDRWRRKLNPKISRGP 51
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
75-118 6.24e-09

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 52.23  E-value: 6.24e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 398364577    75 WDPQDDLLLRHLkeVKKMG---WKDISQYFPNRTPNACQFRWRRLKS 118
Cdd:smart00717   4 WTEEEDELLIEL--VKKYGknnWEKIAKELPGRTAEQCRERWRNLLK 48
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 75-117 9.40e-09

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 51.42  E-value: 9.40e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 398364577  75 WDPQDDLLLRHLkeVKKMG---WKDISQYFPNRTPNACQFRWRRLK 117
Cdd:cd00167    2 WTEEEDELLLEA--VKKYGknnWEKIAKELPGRTPKQCRERWRNLL 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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