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Conserved domains on  [gi|6321287|ref|NP_011364|]
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Nut1p [Saccharomyces cerevisiae S288C]

Protein Classification

mediator of RNA polymerase II transcription subunit 5( domain architecture ID 10554669)

mediator of RNA polymerase II transcription subunit 5 (Med5) such as fungal Med5 which is involved in expression of meiosis and sporulation genes

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Med5 pfam08689
Mediator complex subunit Med5; The mediator complex is required for the expression of nearly ...
1-1127 0e+00

Mediator complex subunit Med5; The mediator complex is required for the expression of nearly all RNA pol II dependent genes in Saccharomyces cerevisiae. Deletion of the MED5 gene leads to increased transcription of nuclear genes encoding components of the oxidative phosphorylation machinery, and decreased transcription of mitochondrial genes encoding components of the same machinery. There is no orthologue from pombe, and this subunit appears to be fungal specific.


:

Pssm-ID: 370064  Cd Length: 1082  Bit Score: 1481.51  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287       1 MEKESVYNLALKCAERQLTSMEFSNLYKEFFNEKFPSLIQEeeedttttaninevkkasdlVDTPSNNTAATadtthlhE 80
Cdd:pfam08689    1 MESESLYKLALKCAERRIPSKEFLNLYKELYNEKPISDIEN--------------------EDSEEESTKAT-------E 53
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287      81 ALDIVCSDFVKILNLEKPLILADYIVEVLLVNYNSDMIKCFLPKLNSVRNSLLLAHFFSKSCSFFAKLSDTLIIDQVRKD 160
Cdd:pfam08689   54 VAEVISSDFVKLLNSGNSLLLADYVVELLFVNYNSELVKAFLPKLYLVDNSTMLIHFLSKSSAFFSKLTDKLVIDQLSKD 133
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     161 LGNVIVPNILSLDMNSMNKELIAIVSKLLQTTLKLSPSPILLTSAGCKNGSFTLLNQLSQTNKLLFKRVSQTFEAKLHFK 240
Cdd:pfam08689  134 LSTEIIPSILSADMNSEGNHLVVAIAKFLQAVLKFHTSPIVIDSDNLRENLNSLLSRLSKINKLLYKKLGQTLDSKLPFK 213
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     241 DTKPFLNKDSTNEFVGSPSLTSPQYIPSPLSSTKPPGSVNSAAKYKDMKLLRYYKNIWLNNKIINWEISNPDFLSKYSAI 320
Cdd:pfam08689  214 DSKPVFTSDSLLNFVDSPSITSPQFIASPLSTTKAPLSLSSGSKYKDMKLLRYYKNLWLNNKIHNWEPSDDDFLSNYASI 293
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     321 TSSIFQESFNSVQNLDQLLTDLIETSFTCFAQFVSNKQYHQANSNLTLLERKWVIFITKHLPLLILENSSRSPRVVTNAL 400
Cdd:pfam08689  294 SSNLFPESSSSLQNVDALLTDLIETSFTCFAQFVSNKQYHQENSNFNLLERKWIIFISKQLPLLILENSSDNPQVITNAL 373
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     401 DNIDEKVVKAIRIYFTEKDDNKTNNEDLFDDYPSTSLDIRHDFIKGLIMLNLQPASVINNYLREDQMIDTSILPTRDDLF 480
Cdd:pfam08689  374 ENIDDKVVKAIKSYYSEKDDIKNRNEDLFDDYPSTSLDIRHDFIKSLIMLGLQPPSVINEYLREDQMVDPKSLPTTDDLI 453
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     481 VRNLQGIQEVVHNTNSFIISSLDTLELESITESiTHDSSNGLFQVLHNFESVAPTKQREIVKAFLSIFEDAIKELNYNRI 560
Cdd:pfam08689  454 ITNSQGVQELVNDIKAFIISSIESLEGEAGADD-SNDSSNGLLQLLNNFETIAPTKQREISNAILDVLSELIDTKNTMTL 532
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     561 AKICALLFFNFSHSLTTILSFSSPAALMKTLIKFVDLSRNGRNGSNGND-ESSEYETINISLSFSWAILLIINLTQTYGI 639
Cdd:pfam08689  533 KKLCALLCFNFSHSLTNILSFVSPESILEPLIKFIDVSWHSSVVSKSDFnDDDDFESQNVYLSFGWILLLIITIVYTYDI 612
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     640 SVVDVALKYPELSIKNSFIINFISNLPNVSDKYYLEESNVNDSDMLTKSHNTVQSWLCDLFVNGSITDQLIQNIETRQLA 719
Cdd:pfam08689  613 SLEDVAITSSELDYINSFIIRLLSKLTDIPDDFTLDESNEEDDELQTKSNKLLQSWLRDLFVNGSISDELMQSCDVKQLY 692
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     720 NLIPFIVKQVLLSVEIGVLTDISSLIGGFEYFLQPLLLVGLIKTFYWLEQFLSCVKNDTISEDILQGIFNLLNTLFNPVT 799
Cdd:pfam08689  693 TLIPFIFKQSLLAVEIGKISDISNLVGGFEYFLQPFLLPGLIKIVYWLEQYLSELKNDDTDEDLLQKILKLLNSIINPSS 772
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     800 LNEDSKAFHTAVLRLNAIPLLKVLRKFRV-QSQSNYGIYSSDAQGDPNLEPLIAKLVAVLNVSPVYDVDPRIINS-ENDY 877
Cdd:pfam08689  773 LNEDSRAFHSAVLRLNAVRLLKVLRKFRVrQSQSNYGIYSSDSQGDPKLESLISKLESVLNISPIYDVDPRIISSqENMY 852
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     878 SRKQLGYGKFLILNENPINKIMTNQINSFWSLHSSTYYNLDYLFELIELVTPKSFLFDVLKTLEYKLATYGVPGSENKRG 957
Cdd:pfam08689  853 SQKQLGYGKFLITNENPINKIMTNQINSFWNLHSSTYYNHDYLNELIDLVTPKKFLFDVLRTLKYKVTSYGVPGSRNKMS 932
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     958 SLDSEHVFDYFFYFLVLYDVKTAEEASQLIEYMENDAKKSKGDVDIKGEDLHEKNDSAEvrqetqpKAEATQDDDFDMLF 1037
Cdd:pfam08689  933 NGESEHVLDYLFYFLVLYDVESQEDASYLIQYMENGSESSVSEITPQKEEVNLKPKSEQ-------DQFNSMDDDFDMLF 1005
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287    1038 GENDTSTQAYEEeeenedndgnnrtNNVPMIKAEETPSKTNKISILKRHSFAVLLHERKLLNDLALENGEITKTENEKFI 1117
Cdd:pfam08689 1006 GENETSLQAPDE-------------ELFSQITVLEKVNKSNNILALKRDSFGVILHEMKLDYDTALEDGDISKEDYEKLC 1072
                         1130
                   ....*....|
gi 6321287    1118 SYHDKYLCML 1127
Cdd:pfam08689 1073 TYHDKYLSML 1082
 
Name Accession Description Interval E-value
Med5 pfam08689
Mediator complex subunit Med5; The mediator complex is required for the expression of nearly ...
1-1127 0e+00

Mediator complex subunit Med5; The mediator complex is required for the expression of nearly all RNA pol II dependent genes in Saccharomyces cerevisiae. Deletion of the MED5 gene leads to increased transcription of nuclear genes encoding components of the oxidative phosphorylation machinery, and decreased transcription of mitochondrial genes encoding components of the same machinery. There is no orthologue from pombe, and this subunit appears to be fungal specific.


Pssm-ID: 370064  Cd Length: 1082  Bit Score: 1481.51  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287       1 MEKESVYNLALKCAERQLTSMEFSNLYKEFFNEKFPSLIQEeeedttttaninevkkasdlVDTPSNNTAATadtthlhE 80
Cdd:pfam08689    1 MESESLYKLALKCAERRIPSKEFLNLYKELYNEKPISDIEN--------------------EDSEEESTKAT-------E 53
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287      81 ALDIVCSDFVKILNLEKPLILADYIVEVLLVNYNSDMIKCFLPKLNSVRNSLLLAHFFSKSCSFFAKLSDTLIIDQVRKD 160
Cdd:pfam08689   54 VAEVISSDFVKLLNSGNSLLLADYVVELLFVNYNSELVKAFLPKLYLVDNSTMLIHFLSKSSAFFSKLTDKLVIDQLSKD 133
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     161 LGNVIVPNILSLDMNSMNKELIAIVSKLLQTTLKLSPSPILLTSAGCKNGSFTLLNQLSQTNKLLFKRVSQTFEAKLHFK 240
Cdd:pfam08689  134 LSTEIIPSILSADMNSEGNHLVVAIAKFLQAVLKFHTSPIVIDSDNLRENLNSLLSRLSKINKLLYKKLGQTLDSKLPFK 213
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     241 DTKPFLNKDSTNEFVGSPSLTSPQYIPSPLSSTKPPGSVNSAAKYKDMKLLRYYKNIWLNNKIINWEISNPDFLSKYSAI 320
Cdd:pfam08689  214 DSKPVFTSDSLLNFVDSPSITSPQFIASPLSTTKAPLSLSSGSKYKDMKLLRYYKNLWLNNKIHNWEPSDDDFLSNYASI 293
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     321 TSSIFQESFNSVQNLDQLLTDLIETSFTCFAQFVSNKQYHQANSNLTLLERKWVIFITKHLPLLILENSSRSPRVVTNAL 400
Cdd:pfam08689  294 SSNLFPESSSSLQNVDALLTDLIETSFTCFAQFVSNKQYHQENSNFNLLERKWIIFISKQLPLLILENSSDNPQVITNAL 373
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     401 DNIDEKVVKAIRIYFTEKDDNKTNNEDLFDDYPSTSLDIRHDFIKGLIMLNLQPASVINNYLREDQMIDTSILPTRDDLF 480
Cdd:pfam08689  374 ENIDDKVVKAIKSYYSEKDDIKNRNEDLFDDYPSTSLDIRHDFIKSLIMLGLQPPSVINEYLREDQMVDPKSLPTTDDLI 453
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     481 VRNLQGIQEVVHNTNSFIISSLDTLELESITESiTHDSSNGLFQVLHNFESVAPTKQREIVKAFLSIFEDAIKELNYNRI 560
Cdd:pfam08689  454 ITNSQGVQELVNDIKAFIISSIESLEGEAGADD-SNDSSNGLLQLLNNFETIAPTKQREISNAILDVLSELIDTKNTMTL 532
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     561 AKICALLFFNFSHSLTTILSFSSPAALMKTLIKFVDLSRNGRNGSNGND-ESSEYETINISLSFSWAILLIINLTQTYGI 639
Cdd:pfam08689  533 KKLCALLCFNFSHSLTNILSFVSPESILEPLIKFIDVSWHSSVVSKSDFnDDDDFESQNVYLSFGWILLLIITIVYTYDI 612
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     640 SVVDVALKYPELSIKNSFIINFISNLPNVSDKYYLEESNVNDSDMLTKSHNTVQSWLCDLFVNGSITDQLIQNIETRQLA 719
Cdd:pfam08689  613 SLEDVAITSSELDYINSFIIRLLSKLTDIPDDFTLDESNEEDDELQTKSNKLLQSWLRDLFVNGSISDELMQSCDVKQLY 692
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     720 NLIPFIVKQVLLSVEIGVLTDISSLIGGFEYFLQPLLLVGLIKTFYWLEQFLSCVKNDTISEDILQGIFNLLNTLFNPVT 799
Cdd:pfam08689  693 TLIPFIFKQSLLAVEIGKISDISNLVGGFEYFLQPFLLPGLIKIVYWLEQYLSELKNDDTDEDLLQKILKLLNSIINPSS 772
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     800 LNEDSKAFHTAVLRLNAIPLLKVLRKFRV-QSQSNYGIYSSDAQGDPNLEPLIAKLVAVLNVSPVYDVDPRIINS-ENDY 877
Cdd:pfam08689  773 LNEDSRAFHSAVLRLNAVRLLKVLRKFRVrQSQSNYGIYSSDSQGDPKLESLISKLESVLNISPIYDVDPRIISSqENMY 852
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     878 SRKQLGYGKFLILNENPINKIMTNQINSFWSLHSSTYYNLDYLFELIELVTPKSFLFDVLKTLEYKLATYGVPGSENKRG 957
Cdd:pfam08689  853 SQKQLGYGKFLITNENPINKIMTNQINSFWNLHSSTYYNHDYLNELIDLVTPKKFLFDVLRTLKYKVTSYGVPGSRNKMS 932
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     958 SLDSEHVFDYFFYFLVLYDVKTAEEASQLIEYMENDAKKSKGDVDIKGEDLHEKNDSAEvrqetqpKAEATQDDDFDMLF 1037
Cdd:pfam08689  933 NGESEHVLDYLFYFLVLYDVESQEDASYLIQYMENGSESSVSEITPQKEEVNLKPKSEQ-------DQFNSMDDDFDMLF 1005
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287    1038 GENDTSTQAYEEeeenedndgnnrtNNVPMIKAEETPSKTNKISILKRHSFAVLLHERKLLNDLALENGEITKTENEKFI 1117
Cdd:pfam08689 1006 GENETSLQAPDE-------------ELFSQITVLEKVNKSNNILALKRDSFGVILHEMKLDYDTALEDGDISKEDYEKLC 1072
                         1130
                   ....*....|
gi 6321287    1118 SYHDKYLCML 1127
Cdd:pfam08689 1073 TYHDKYLSML 1082
 
Name Accession Description Interval E-value
Med5 pfam08689
Mediator complex subunit Med5; The mediator complex is required for the expression of nearly ...
1-1127 0e+00

Mediator complex subunit Med5; The mediator complex is required for the expression of nearly all RNA pol II dependent genes in Saccharomyces cerevisiae. Deletion of the MED5 gene leads to increased transcription of nuclear genes encoding components of the oxidative phosphorylation machinery, and decreased transcription of mitochondrial genes encoding components of the same machinery. There is no orthologue from pombe, and this subunit appears to be fungal specific.


Pssm-ID: 370064  Cd Length: 1082  Bit Score: 1481.51  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287       1 MEKESVYNLALKCAERQLTSMEFSNLYKEFFNEKFPSLIQEeeedttttaninevkkasdlVDTPSNNTAATadtthlhE 80
Cdd:pfam08689    1 MESESLYKLALKCAERRIPSKEFLNLYKELYNEKPISDIEN--------------------EDSEEESTKAT-------E 53
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287      81 ALDIVCSDFVKILNLEKPLILADYIVEVLLVNYNSDMIKCFLPKLNSVRNSLLLAHFFSKSCSFFAKLSDTLIIDQVRKD 160
Cdd:pfam08689   54 VAEVISSDFVKLLNSGNSLLLADYVVELLFVNYNSELVKAFLPKLYLVDNSTMLIHFLSKSSAFFSKLTDKLVIDQLSKD 133
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     161 LGNVIVPNILSLDMNSMNKELIAIVSKLLQTTLKLSPSPILLTSAGCKNGSFTLLNQLSQTNKLLFKRVSQTFEAKLHFK 240
Cdd:pfam08689  134 LSTEIIPSILSADMNSEGNHLVVAIAKFLQAVLKFHTSPIVIDSDNLRENLNSLLSRLSKINKLLYKKLGQTLDSKLPFK 213
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     241 DTKPFLNKDSTNEFVGSPSLTSPQYIPSPLSSTKPPGSVNSAAKYKDMKLLRYYKNIWLNNKIINWEISNPDFLSKYSAI 320
Cdd:pfam08689  214 DSKPVFTSDSLLNFVDSPSITSPQFIASPLSTTKAPLSLSSGSKYKDMKLLRYYKNLWLNNKIHNWEPSDDDFLSNYASI 293
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     321 TSSIFQESFNSVQNLDQLLTDLIETSFTCFAQFVSNKQYHQANSNLTLLERKWVIFITKHLPLLILENSSRSPRVVTNAL 400
Cdd:pfam08689  294 SSNLFPESSSSLQNVDALLTDLIETSFTCFAQFVSNKQYHQENSNFNLLERKWIIFISKQLPLLILENSSDNPQVITNAL 373
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     401 DNIDEKVVKAIRIYFTEKDDNKTNNEDLFDDYPSTSLDIRHDFIKGLIMLNLQPASVINNYLREDQMIDTSILPTRDDLF 480
Cdd:pfam08689  374 ENIDDKVVKAIKSYYSEKDDIKNRNEDLFDDYPSTSLDIRHDFIKSLIMLGLQPPSVINEYLREDQMVDPKSLPTTDDLI 453
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     481 VRNLQGIQEVVHNTNSFIISSLDTLELESITESiTHDSSNGLFQVLHNFESVAPTKQREIVKAFLSIFEDAIKELNYNRI 560
Cdd:pfam08689  454 ITNSQGVQELVNDIKAFIISSIESLEGEAGADD-SNDSSNGLLQLLNNFETIAPTKQREISNAILDVLSELIDTKNTMTL 532
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     561 AKICALLFFNFSHSLTTILSFSSPAALMKTLIKFVDLSRNGRNGSNGND-ESSEYETINISLSFSWAILLIINLTQTYGI 639
Cdd:pfam08689  533 KKLCALLCFNFSHSLTNILSFVSPESILEPLIKFIDVSWHSSVVSKSDFnDDDDFESQNVYLSFGWILLLIITIVYTYDI 612
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     640 SVVDVALKYPELSIKNSFIINFISNLPNVSDKYYLEESNVNDSDMLTKSHNTVQSWLCDLFVNGSITDQLIQNIETRQLA 719
Cdd:pfam08689  613 SLEDVAITSSELDYINSFIIRLLSKLTDIPDDFTLDESNEEDDELQTKSNKLLQSWLRDLFVNGSISDELMQSCDVKQLY 692
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     720 NLIPFIVKQVLLSVEIGVLTDISSLIGGFEYFLQPLLLVGLIKTFYWLEQFLSCVKNDTISEDILQGIFNLLNTLFNPVT 799
Cdd:pfam08689  693 TLIPFIFKQSLLAVEIGKISDISNLVGGFEYFLQPFLLPGLIKIVYWLEQYLSELKNDDTDEDLLQKILKLLNSIINPSS 772
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     800 LNEDSKAFHTAVLRLNAIPLLKVLRKFRV-QSQSNYGIYSSDAQGDPNLEPLIAKLVAVLNVSPVYDVDPRIINS-ENDY 877
Cdd:pfam08689  773 LNEDSRAFHSAVLRLNAVRLLKVLRKFRVrQSQSNYGIYSSDSQGDPKLESLISKLESVLNISPIYDVDPRIISSqENMY 852
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     878 SRKQLGYGKFLILNENPINKIMTNQINSFWSLHSSTYYNLDYLFELIELVTPKSFLFDVLKTLEYKLATYGVPGSENKRG 957
Cdd:pfam08689  853 SQKQLGYGKFLITNENPINKIMTNQINSFWNLHSSTYYNHDYLNELIDLVTPKKFLFDVLRTLKYKVTSYGVPGSRNKMS 932
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287     958 SLDSEHVFDYFFYFLVLYDVKTAEEASQLIEYMENDAKKSKGDVDIKGEDLHEKNDSAEvrqetqpKAEATQDDDFDMLF 1037
Cdd:pfam08689  933 NGESEHVLDYLFYFLVLYDVESQEDASYLIQYMENGSESSVSEITPQKEEVNLKPKSEQ-------DQFNSMDDDFDMLF 1005
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321287    1038 GENDTSTQAYEEeeenedndgnnrtNNVPMIKAEETPSKTNKISILKRHSFAVLLHERKLLNDLALENGEITKTENEKFI 1117
Cdd:pfam08689 1006 GENETSLQAPDE-------------ELFSQITVLEKVNKSNNILALKRDSFGVILHEMKLDYDTALEDGDISKEDYEKLC 1072
                         1130
                   ....*....|
gi 6321287    1118 SYHDKYLCML 1127
Cdd:pfam08689 1073 TYHDKYLSML 1082
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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