NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|398366235|ref|NP_011746|]
View 

Bns1p [Saccharomyces cerevisiae S288C]

Protein Classification

Spo12 family protein( domain architecture ID 10523492)

Spo12 family protein similar to Schizosaccharomyces pombe mitosis-specific protein spo12 that plays a regulatory role in mitosis and meiosis

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Spo12 pfam05032
Spo12 family; This family of proteins includes Spo12 from S. cerevisiae. The Spo12 protein ...
89-121 3.41e-12

Spo12 family; This family of proteins includes Spo12 from S. cerevisiae. The Spo12 protein plays a regulatory role in two of the most fundamental processes of biology, mitosis and meiosis, and yet its biochemical function remains elusive. Spo12 is a nuclear protein. Spo12 is a component of the FEAR (Cdc fourteen early anaphase release) regulatory network, that promotes Cdc14 release from the nucleolus during early anaphase. The FEAR network is comprised of the polo kinase Cdc5, the separase Esp1, the kinetochore-associated protein Slk19, and Spo12.


:

Pssm-ID: 398624  Cd Length: 33  Bit Score: 56.96  E-value: 3.41e-12
                          10        20        30
                  ....*....|....*....|....*....|...
gi 398366235   89 ASPSDNLLSPCSRKLNDHKSKLFSAKSQPKTLE 121
Cdd:pfam05032   1 VSPTDNLMSPCSQKLNAHKSKLFKKKSKPTKLL 33
 
Name Accession Description Interval E-value
Spo12 pfam05032
Spo12 family; This family of proteins includes Spo12 from S. cerevisiae. The Spo12 protein ...
89-121 3.41e-12

Spo12 family; This family of proteins includes Spo12 from S. cerevisiae. The Spo12 protein plays a regulatory role in two of the most fundamental processes of biology, mitosis and meiosis, and yet its biochemical function remains elusive. Spo12 is a nuclear protein. Spo12 is a component of the FEAR (Cdc fourteen early anaphase release) regulatory network, that promotes Cdc14 release from the nucleolus during early anaphase. The FEAR network is comprised of the polo kinase Cdc5, the separase Esp1, the kinetochore-associated protein Slk19, and Spo12.


Pssm-ID: 398624  Cd Length: 33  Bit Score: 56.96  E-value: 3.41e-12
                          10        20        30
                  ....*....|....*....|....*....|...
gi 398366235   89 ASPSDNLLSPCSRKLNDHKSKLFSAKSQPKTLE 121
Cdd:pfam05032   1 VSPTDNLMSPCSQKLNAHKSKLFKKKSKPTKLL 33
 
Name Accession Description Interval E-value
Spo12 pfam05032
Spo12 family; This family of proteins includes Spo12 from S. cerevisiae. The Spo12 protein ...
89-121 3.41e-12

Spo12 family; This family of proteins includes Spo12 from S. cerevisiae. The Spo12 protein plays a regulatory role in two of the most fundamental processes of biology, mitosis and meiosis, and yet its biochemical function remains elusive. Spo12 is a nuclear protein. Spo12 is a component of the FEAR (Cdc fourteen early anaphase release) regulatory network, that promotes Cdc14 release from the nucleolus during early anaphase. The FEAR network is comprised of the polo kinase Cdc5, the separase Esp1, the kinetochore-associated protein Slk19, and Spo12.


Pssm-ID: 398624  Cd Length: 33  Bit Score: 56.96  E-value: 3.41e-12
                          10        20        30
                  ....*....|....*....|....*....|...
gi 398366235   89 ASPSDNLLSPCSRKLNDHKSKLFSAKSQPKTLE 121
Cdd:pfam05032   1 VSPTDNLMSPCSQKLNAHKSKLFKKKSKPTKLL 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH