|
Name |
Accession |
Description |
Interval |
E-value |
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
4-315 |
1.44e-149 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 422.16 E-value: 1.44e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 4 NSIKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIItQIGSGVVNDRVLELLIMINASKTA 83
Cdd:COG0462 2 KDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVI-QSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 84 SARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENvN 163
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSK-D 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 164 YMDSIIISPDAGGAKRAATLADRLDLNFALIHKERARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILLENRA 243
Cdd:COG0462 160 LEDLVVVSPDVGGVKRARAFAKRLGAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEAGA 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6321776 244 KSVIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEEKiKKCPKLAVIDISSVLAESIRRLHNGESISYLF 315
Cdd:COG0462 240 KSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEE-KRCDKIKVLSVAPLLAEAIRRIHEGESVSSLF 310
|
|
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
6-315 |
1.99e-145 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 411.82 E-value: 1.99e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 6 IKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIItQIGSGVVNDRVLELLIMINASKTASA 85
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFII-QSTCAPTNDNLMELLIMIDALKRASA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 86 RRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENvNYM 165
Cdd:PRK01259 80 GRITAVIPYFGYARQDRKARSRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQK-NLE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 166 DSIIISPDAGGAKRAATLADRLDLNFALIHKERARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILLENRAKS 245
Cdd:PRK01259 159 NLVVVSPDVGGVVRARALAKRLDADLAIIDKRRPRANVSEVMNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKS 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 246 VIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEEKIKKCPKLAVIDISSVLAESIRRLHNGESISYLF 315
Cdd:PRK01259 239 VYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIRVLSVAPLLAEAIRRISNEESVSSLF 308
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
6-315 |
1.02e-127 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 366.99 E-value: 1.02e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 6 IKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIITQIGSGVVNDRVLELLIMINASKTASA 85
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIQQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 86 RRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENvNYM 165
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKSREPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKK-ILD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 166 DSIIISPDAGGAKRAATLADRLDLNFALIHKER-ARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILLENRAK 244
Cdd:TIGR01251 160 NPVVVSPDAGGVERAKKVADALGCPLAIIDKRRiSATNEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGAK 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6321776 245 SVIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEekiKKCPKLAVIDISSVLAESIRRLHNGESISYLF 315
Cdd:TIGR01251 240 RVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHE---KHKPKVSVISVAPLIAEAIRRIHNNESVSSLF 307
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
6-123 |
8.84e-55 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 174.15 E-value: 8.84e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 6 IKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIItQIGSGVVNDRVLELLIMINASKTASA 85
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFII-QSTCPPVNDNLMELLIMIDALKRASA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 6321776 86 RRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAG 123
Cdd:pfam13793 80 KRITAVIPYFGYARQDRKDKPREPITAKLVADLLEAAG 117
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
154-276 |
6.98e-23 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 91.69 E-value: 6.98e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 154 VVRYIKENvNYMDSIIISPDAGGAKRAATLADRLDLNFALIHKERARANEVSRM------VLVGDVTDKICIIVDDMADT 227
Cdd:cd06223 5 LAEEIRED-LLEPDVVVGILRGGLPLAAALARALGLPLAFIRKERKGPGRTPSEpyglelPLGGDVKGKRVLLVDDVIAT 83
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 6321776 228 CGTLAKAAEILLENRAKSVIAIVTHGVLSGRAIEniNNSKLDRVVCTNT 276
Cdd:cd06223 84 GGTLLAAIELLKEAGAKVVGVAVLLDKPEGGARE--LASPGDPVYSLFT 130
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
4-315 |
1.44e-149 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 422.16 E-value: 1.44e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 4 NSIKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIItQIGSGVVNDRVLELLIMINASKTA 83
Cdd:COG0462 2 KDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVI-QSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 84 SARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENvN 163
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSK-D 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 164 YMDSIIISPDAGGAKRAATLADRLDLNFALIHKERARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILLENRA 243
Cdd:COG0462 160 LEDLVVVSPDVGGVKRARAFAKRLGAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEAGA 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6321776 244 KSVIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEEKiKKCPKLAVIDISSVLAESIRRLHNGESISYLF 315
Cdd:COG0462 240 KSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEE-KRCDKIKVLSVAPLLAEAIRRIHEGESVSSLF 310
|
|
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
6-315 |
1.99e-145 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 411.82 E-value: 1.99e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 6 IKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIItQIGSGVVNDRVLELLIMINASKTASA 85
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFII-QSTCAPTNDNLMELLIMIDALKRASA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 86 RRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENvNYM 165
Cdd:PRK01259 80 GRITAVIPYFGYARQDRKARSRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQK-NLE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 166 DSIIISPDAGGAKRAATLADRLDLNFALIHKERARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILLENRAKS 245
Cdd:PRK01259 159 NLVVVSPDVGGVVRARALAKRLDADLAIIDKRRPRANVSEVMNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKS 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 246 VIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEEKIKKCPKLAVIDISSVLAESIRRLHNGESISYLF 315
Cdd:PRK01259 239 VYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIRVLSVAPLLAEAIRRISNEESVSSLF 308
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
6-315 |
1.02e-127 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 366.99 E-value: 1.02e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 6 IKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIITQIGSGVVNDRVLELLIMINASKTASA 85
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIQQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 86 RRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENvNYM 165
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKSREPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKK-ILD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 166 DSIIISPDAGGAKRAATLADRLDLNFALIHKER-ARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILLENRAK 244
Cdd:TIGR01251 160 NPVVVSPDAGGVERAKKVADALGCPLAIIDKRRiSATNEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGAK 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6321776 245 SVIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEekiKKCPKLAVIDISSVLAESIRRLHNGESISYLF 315
Cdd:TIGR01251 240 RVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHE---KHKPKVSVISVAPLIAEAIRRIHNNESVSSLF 307
|
|
| PRK03092 |
PRK03092 |
ribose-phosphate diphosphokinase; |
17-319 |
4.32e-104 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179535 [Multi-domain] Cd Length: 304 Bit Score: 306.87 E-value: 4.32e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 17 LAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIItQIGSGVVNDRVLELLIMINASKTASARRITAIIPNFP 96
Cdd:PRK03092 1 LAEEVAKELGVEVTPTTAYDFANGEIYVRFEESVRGCDAFVL-QSHTAPINKWLMEQLIMIDALKRASAKRITVVLPFYP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 97 YARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENVNYMDSIIISPDAGG 176
Cdd:PRK03092 80 YARQDKKHRGREPISARLVADLFKTAGADRIMTVDLHTAQIQGFFDGPVDHLFAMPLLADYVRDKYDLDNVTVVSPDAGR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 177 AKRAATLADRL-DLNFALIHKER--ARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILLENRAKSVIAIVTHG 253
Cdd:PRK03092 160 VRVAEQWADRLgGAPLAFIHKTRdpTVPNQVVANRVVGDVEGRTCVLVDDMIDTGGTIAGAVRALKEAGAKDVIIAATHG 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6321776 254 VLSGRAIENINNSKLDRVVCTNTVPFEEKiKKCPKLAVIDISSVLAESIRRLHNGESISYLFKNYP 319
Cdd:PRK03092 240 VLSGPAAERLKNCGAREVVVTDTLPIPEE-KRFDKLTVLSIAPLLARAIREVFEDGSVTSLFDGLA 304
|
|
| PRK04923 |
PRK04923 |
ribose-phosphate diphosphokinase; |
1-315 |
1.60e-100 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179893 [Multi-domain] Cd Length: 319 Bit Score: 298.38 E-value: 1.60e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 1 MPTNSIKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIItQIGSGVVNDRVLELLIMINAS 80
Cdd:PRK04923 2 QDQRNLLVFSGNANKPLAQSICKELGVRMGKALVTRFSDGEVQVEIEESVRRQEVFVI-QPTCAPSAENLMELLVLIDAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 81 KTASARRITAIIPNFPYARQDRKDKS-RAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIK 159
Cdd:PRK04923 81 KRASAASVTAVIPYFGYSRQDRRMRSsRVPITAKVAAKMISAMGADRVLTVDLHADQIQGFFDVPVDNVYASPLLLADIW 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 160 ENVNYMDSIIISPDAGGAKRAATLADRL-DLNFALIHKERARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEIL 238
Cdd:PRK04923 161 RAYGTDNLIVVSPDVGGVVRARAVAKRLdDADLAIIDKRRPRANVATVMNIIGDVQGKTCVLVDDLVDTAGTLCAAAAAL 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6321776 239 LENRAKSVIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEEKIKKCPKLAVIDISSVLAESIRRLHNGESISYLF 315
Cdd:PRK04923 241 KQRGALKVVAYITHPVLSGPAVDNINNSQLDELVVTDTIPLSEAARACAKIRQLSVAELLAETIRRIAFGESVSSLY 317
|
|
| PLN02369 |
PLN02369 |
ribose-phosphate pyrophosphokinase |
15-316 |
1.82e-98 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 215209 [Multi-domain] Cd Length: 302 Bit Score: 292.37 E-value: 1.82e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 15 RGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIItQIGSGVVNDRVLELLIMINASKTASARRITAIIPN 94
Cdd:PLN02369 1 PALSQEIACYLGLELGKITIKRFADGEIYVQLQESVRGCDVFLV-QPTCPPANENLMELLIMIDACRRASAKRITAVIPY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 95 FPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYI-KENVNYMDSIIISPD 173
Cdd:PLN02369 80 FGYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLaSKTISSPDLVVVSPD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 174 AGGAKRAATLADRL-DLNFALIHKERARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILLENRAKSVIAIVTH 252
Cdd:PLN02369 160 VGGVARARAFAKKLsDAPLAIVDKRRQGHNVAEVMNLIGDVKGKVAIMVDDMIDTAGTITKGAALLHQEGAREVYACATH 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6321776 253 GVLSGRAIENINNSKLDRVVCTNTVPFEEKiKKCPKLAVIDISSVLAESIRRLHNGESISYLFK 316
Cdd:PLN02369 240 AVFSPPAIERLSSGLFQEVIVTNTIPVSEK-NYFPQLTVLSVANLLGETIWRVHDDCSVSSIFD 302
|
|
| PTZ00145 |
PTZ00145 |
phosphoribosylpyrophosphate synthetase; Provisional |
8-315 |
3.39e-91 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 240290 [Multi-domain] Cd Length: 439 Bit Score: 278.68 E-value: 3.39e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 8 LLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIItQIGSGVVNDRVLELLIMINASKTASARR 87
Cdd:PTZ00145 122 LFSGSSNPLLSKNIADHLGTILGRVHLKRFADGEVSMQFLESIRGKDVYII-QPTCPPVNENLIELLLMISTCRRASAKK 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 88 ITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFD--VPVDNLYAEPSVVRYIKENVNYm 165
Cdd:PTZ00145 201 ITAVIPYYGYARQDRKLSSRVPISAADVARMIEAMGVDRVVAIDLHSGQIQGFFGprVPVDNLEAQLIGLDYFTKKDLY- 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 166 DSIIISPDAGGAKRAATLADRL------DLNFALIHKERARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILL 239
Cdd:PTZ00145 280 KPVIVSPDAGGVYRARKFQDGLnhrgisDCGIAMLIKQRTKPNEIEKMDLVGNVYDSDVIIVDDMIDTSGTLCEAAKQLK 359
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6321776 240 ENRAKSVIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEEKIKKCPKLAVIDISSVLAESIRRLHNGESISYLF 315
Cdd:PTZ00145 360 KHGARRVFAFATHGLFSGPAIERIEASPLEEVVVTDTVKSNKNIDSCKKITKLSVSVLVADAIRRIHQKESLNDLF 435
|
|
| PRK02812 |
PRK02812 |
ribose-phosphate pyrophosphokinase; Provisional |
3-316 |
3.12e-89 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235072 [Multi-domain] Cd Length: 330 Bit Score: 269.69 E-value: 3.12e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 3 TNSIKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIItQIGSGVVNDRVLELLIMINASKT 82
Cdd:PRK02812 19 NNRLRLFSGSSNPALAQEVARYLGMDLGPMIRKRFADGELYVQIQESIRGCDVYLI-QPTCAPVNDHLMELLIMVDACRR 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 83 ASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENv 162
Cdd:PRK02812 98 ASARQITAVIPYYGYARADRKTAGRESITAKLVANLITKAGADRVLAMDLHSAQIQGYFDIPCDHVYGSPVLLDYLASK- 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 163 NYMDSIIISPDAGGAKRAATLADRL-DLNFALIHKERARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILLEN 241
Cdd:PRK02812 177 NLEDIVVVSPDVGGVARARAFAKKLnDAPLAIIDKRRQAHNVAEVLNVIGDVKGKTAILVDDMIDTGGTICEGARLLRKE 256
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6321776 242 RAKSVIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEEKiKKCPKLAVIDISSVLAESIRRLHNGESISYLFK 316
Cdd:PRK02812 257 GAKQVYACATHAVFSPPAIERLSSGLFEEVIVTNTIPVPEE-RRFPQLKVLSVANMLGEAIWRIHEESSVSSMFR 330
|
|
| PRK02269 |
PRK02269 |
ribose-phosphate diphosphokinase; |
1-316 |
2.04e-88 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 167353 [Multi-domain] Cd Length: 320 Bit Score: 267.43 E-value: 2.04e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 1 MPTNSIKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIItQIGSGVVNDRVLELLIMINAS 80
Cdd:PRK02269 1 MSYSDLKLFALSSNKELAEKVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGHHVFIL-QSTSSPVNDNLMEILIMVDAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 81 KTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKE 160
Cdd:PRK02269 80 KRASAESINVVMPYYGYARQDRKARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 161 -NVNYMDSIIISPDAGGAKRAATLADRLDLNFALIHKERA--RANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEI 237
Cdd:PRK02269 160 rGLVGDDVVVVSPDHGGVTRARKLAQFLKTPIAIIDKRRSvdKMNTSEVMNIIGNVKGKKCILIDDMIDTAGTICHAADA 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6321776 238 LLENRAKSVIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEEKiKKCPKLAVIDISSVLAESIRRLHNGESISYLFK 316
Cdd:PRK02269 240 LAEAGATEVYASCTHPVLSGPALDNIQKSAIEKLVVLDTIYLPEE-RLIDKIEQISIADLLGEAIIRIHEKRPLSPLFE 317
|
|
| PRK02458 |
PRK02458 |
ribose-phosphate pyrophosphokinase; Provisional |
6-316 |
2.44e-78 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235039 [Multi-domain] Cd Length: 323 Bit Score: 241.95 E-value: 2.44e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 6 IKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIItQIGSGVVNDRVLELLIMINASKTASA 85
Cdd:PRK02458 10 IKLFSLNSNLEIAEKIAQAAGVPLGKLSSRQFSDGEIMINIEESVRGDDIYII-QSTSFPVNDHLWELLIMIDACKRASA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 86 RRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENVNY- 164
Cdd:PRK02458 89 NTVNVVLPYFGYARQDRIAKPREPITAKLVANMLVKAGVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCKKGLSg 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 165 MDSIIISPDAGGAKRAATLADRLDLNFALIHKERARANEvSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILLENRAK 244
Cdd:PRK02458 169 SDVVVVSPKNSGIKRARSLAEYLDAPIAIIDYAQDDSER-EEGYIIGDVAGKKAILIDDILNTGKTFAEAAKIVEREGAT 247
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6321776 245 SVIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEEKIKKcpKLAVIDISSVLAESIRRLHNGESISYLFK 316
Cdd:PRK02458 248 EIYAVASHGLFAGGAAEVLENAPIKEILVTDSVATKERVPK--NVTYLSASELIADAIIRIHERKPLSPLFA 317
|
|
| PRK00553 |
PRK00553 |
ribose-phosphate pyrophosphokinase; Provisional |
17-318 |
1.15e-76 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 179062 [Multi-domain] Cd Length: 332 Bit Score: 237.89 E-value: 1.15e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 17 LAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIItQIGSGVVNDRVLELLIMINASKTASARRITAIIPNFP 96
Cdd:PRK00553 21 LVDSICRKLSMKPGEIVIQKFADGETYIRFDESVRNKDVVIF-QSTCSPVNDSLMELLIAIDALKRGSAKSITAILPYYG 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 97 YARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENVNYMDSIIISPDAGG 176
Cdd:PRK00553 100 YARQDRKTAGREPITSKLVADLLTKAGVTRVTLTDIHSDQTQGFFDIPVDILRTYHVFLSRVLELLGKKDLVVVSPDYGG 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 177 AKRAATLADRLDLNFALIHKERARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILLENRAKSVIAIVTHGVLS 256
Cdd:PRK00553 180 VKRARLIAESLELPLAIIDKRRPKHNVAESINVLGEVKNKNCLIVDDMIDTGGTVIAAAKLLKKQKAKKVCVMATHGLFN 259
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6321776 257 GRAIENI----NNSKLDRVVCTNTVPfEEKIKKCPKLAVIDISSVLAESIRRLHNGESISYLFKNY 318
Cdd:PRK00553 260 KNAIQLFdeafKKKLIDKLFVSNSIP-QTKFEKKPQFKVVDLAHLYEEVLLCYANGGSISAIYTRH 324
|
|
| PRK00934 |
PRK00934 |
ribose-phosphate pyrophosphokinase; Provisional |
17-304 |
2.46e-60 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 234868 [Multi-domain] Cd Length: 285 Bit Score: 194.36 E-value: 2.46e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 17 LAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFII----TQigsgvvNDRVLELLIMINASKTASARRITAII 92
Cdd:PRK00934 11 LASEVARLLNTELALVETKRFPDGELYVRILGEIDGEDVVIIsttyPQ------DENLVELLLLIDALRDEGAKSITLVI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 93 PNFPYARQDRKDKSRAPITAKLMADMLTTAgCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENVNymDSIIISP 172
Cdd:PRK00934 85 PYLGYARQDKRFKPGEPISARAIAKIISAY-YDRIITINIHEPSILEFFPIPFINLDAAPLIAEYIGDKLD--DPLVLAP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 173 DAGGAKRAATLADRLDLNFALIHKERARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILLENRAKSVIAIVTH 252
Cdd:PRK00934 162 DKGALELAKEAAEILGCEYDYLEKTRISPTEVEIAPKNLDVKGKDVLIVDDIISTGGTMATAIKILKEQGAKKVYVACVH 241
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 6321776 253 GVLSGRAIENINNSKLDRVVCTNTVPFEEKIkkcpklavIDISSVLAESIRR 304
Cdd:PRK00934 242 PVLVGDAILKLYNAGVDEIIVTDTLESEVSK--------ISVAPLIADLLKK 285
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
6-123 |
8.84e-55 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 174.15 E-value: 8.84e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 6 IKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIItQIGSGVVNDRVLELLIMINASKTASA 85
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFII-QSTCPPVNDNLMELLIMIDALKRASA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 6321776 86 RRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAG 123
Cdd:pfam13793 80 KRITAVIPYFGYARQDRKDKPREPITAKLVADLLEAAG 117
|
|
| Pribosyl_synth |
pfam14572 |
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ... |
163-316 |
1.33e-42 |
|
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.
Pssm-ID: 434046 Cd Length: 184 Bit Score: 145.35 E-value: 1.33e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 163 NYMDSIIISPDAGGAKRAATLADRLDLNFALIHKE------------------RARANEVSR------------MVLVGD 212
Cdd:pfam14572 1 DYRNAVIVARSPGSAKRATSFAERLRLGIAVIHGEqkeaesdevdgrqspppyRSRTVSRSLglpeiipkekppMTVVGD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 213 VTDKICIIVDDMADTCGTLAKAAEILLENRAKSVIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEEKIKKCPKLAVI 292
Cdd:pfam14572 81 VGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQKMQCHKIKTI 160
|
170 180
....*....|....*....|....
gi 6321776 293 DISSVLAESIRRLHNGESISYLFK 316
Cdd:pfam14572 161 DISQLIAEAIRRIHNGESMSYLFR 184
|
|
| PRK06827 |
PRK06827 |
phosphoribosylpyrophosphate synthetase; Provisional |
39-317 |
8.26e-40 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 180714 [Multi-domain] Cd Length: 382 Bit Score: 143.55 E-value: 8.26e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 39 TGEVSFSIGESVRDQDIFIITQIGSGVV-------------NDRVLELLIMINASKtASARRITAIIPNFPYARQDRKdK 105
Cdd:PRK06827 64 NGEAKGEILESVRGKDIYILQDVGNYSVtynmfgeknhmspDDHFQDLKRTIDAIR-GKARRITVIMPFLYESRQHKR-K 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 106 SRAPITAKLMADMLTTAGCDHVITMDLHASQIQ------GFfdvpvDNLYAEPSVVRYIKEN-----VNYMDSIIISPDA 174
Cdd:PRK06827 142 GRESLDCALALQELEELGVDNIITFDAHDPRIEnaiplmGF-----ENLYPSYQIIKALLKNekdleIDKDHLMVISPDT 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 175 GGAKRAATLADRLDLNFALIHKER-------ARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILLENRAKSVI 247
Cdd:PRK06827 217 GAMDRAKYYASVLGVDLGLFYKRRdysrvvnGRNPIVAHEFLGRDVEGKDVLIVDDMIASGGSMIDAAKELKSRGAKKII 296
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6321776 248 AIVTHGVLSgRAIENI----NNSKLDRVVCTNTVPFEEKIKKCPKLAVIDISSVLAESIRRLHNGESISYLFKN 317
Cdd:PRK06827 297 VAATFGFFT-NGLEKFdkayEEGYFDRIIGTNLVYHPEELLSKPWYIEVDMSKLIARIIDALNHDVSLSKLLDP 369
|
|
| PRK07199 |
PRK07199 |
ribose-phosphate diphosphokinase; |
8-305 |
9.91e-33 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 235960 [Multi-domain] Cd Length: 301 Bit Score: 122.74 E-value: 9.91e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 8 LLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIITQIGSGvvNDRVLELLIMINASKTASARR 87
Cdd:PRK07199 5 LLALPGNEAAAGRLAAALGVEVGRIELHRFPDGESYVRLDSPVAGRTVVLVCSLDRP--DEKLLPLLFAAEAARELGARR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 88 ITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAgCDHVITMDLH---ASQIQGFFDVPVDNLYAEPSVVRYIKENVNy 164
Cdd:PRK07199 83 VGLVAPYLAYMRQDIAFHPGEAISQRHFARLLSGS-FDRLVTVDPHlhrYPSLSEVYPIPAVVLSAAPAIAAWIRAHVP- 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 165 mDSIIISPDAGGAKRAATLADRLDLNFALIHKER--ARANEVSrmvlVGDVT---DKICIIVDDMADTCGTLAKAAEILL 239
Cdd:PRK07199 161 -RPLLIGPDEESEQWVAAVAERAGAPHAVLRKTRhgDRDVEIS----LPDAApwaGRTPVLVDDIVSTGRTLIEAARQLR 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6321776 240 ENRAKSVIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEEKikkcpklaVIDISSVLAESIRRL 305
Cdd:PRK07199 236 AAGAASPDCVVVHALFAGDAYSALAAAGIARVVSTDTVPHPSN--------AISLAPLLAEALRRE 293
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
154-276 |
6.98e-23 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 91.69 E-value: 6.98e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 154 VVRYIKENvNYMDSIIISPDAGGAKRAATLADRLDLNFALIHKERARANEVSRM------VLVGDVTDKICIIVDDMADT 227
Cdd:cd06223 5 LAEEIRED-LLEPDVVVGILRGGLPLAAALARALGLPLAFIRKERKGPGRTPSEpyglelPLGGDVKGKRVLLVDDVIAT 83
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 6321776 228 CGTLAKAAEILLENRAKSVIAIVTHGVLSGRAIEniNNSKLDRVVCTNT 276
Cdd:cd06223 84 GGTLLAAIELLKEAGAKVVGVAVLLDKPEGGARE--LASPGDPVYSLFT 130
|
|
| Pribosyltran |
pfam00156 |
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl ... |
144-258 |
1.88e-11 |
|
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase. Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1. Amidophosphoribosyltransferase EC:2.4.2.14. Orotate phosphoribosyl-transferase EC:2.4.2.10. Uracil phosphoribosyl-transferase EC:2.4.2.9. Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22. In Arabidopsis, At the very N-terminus of this domain is the P-Loop NTPase domain.
Pssm-ID: 425489 [Multi-domain] Cd Length: 150 Bit Score: 61.23 E-value: 1.88e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 144 PVDNLYAEPSVVRYIK-------ENVNYMDSIIISPDAGGAKRAATLADRLDLNFALIHKERARAN---EVSRMVLVGDV 213
Cdd:pfam00156 1 SVDEILDNPAILKAVArlaaqinEDYGGKPDVVVGILRGGLPFAGILARRLDVPLAFVRKVSYNPDtseVMKTSSALPDL 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 6321776 214 TDKICIIVDDMADTCGTLAKAAEILLENRAKSVIAIVTHGVLSGR 258
Cdd:pfam00156 81 KGKTVLIVDDILDTGGTLLKVLELLKNVGPKEVKIAVLIDKPAGT 125
|
|
| PLN02297 |
PLN02297 |
ribose-phosphate pyrophosphokinase |
89-261 |
4.85e-09 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 177934 [Multi-domain] Cd Length: 326 Bit Score: 56.62 E-value: 4.85e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 89 TAIIPNFPYARQDRKDKSRAPITAKLMADMLTT-----AGCDHVITMDLHASQIQGFFDVPVDNLYAE--PSVVRYIKEN 161
Cdd:PLN02297 100 TLVLPFFPTGTSERVEREGDVATAFTLARILSNipisrGGPTSLVIFDIHALQERFYFGDNVLPCFESgiPLLKKRLQQL 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321776 162 VNYMDSIIISPDAGGAKRAATLADrldlNFALIHKERARANEVsRMVLV--GDVTDKICIIVDDMADTCGTLAKAAEILL 239
Cdd:PLN02297 180 PDSDNIVIAFPDDGAWKRFHKQFE----HFPMVVCTKVREGDK-RIVRIkeGNPAGRHVVIVDDLVQSGGTLIECQKVLA 254
|
170 180
....*....|....*....|..
gi 6321776 240 ENRAKSVIAIVTHGVLSGRAIE 261
Cdd:PLN02297 255 AHGAAKVSAYVTHGVFPNESWE 276
|
|
| |
