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Conserved domains on  [gi|6322121|ref|NP_012196|]
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SNARE-binding exocyst subunit SEC6 [Saccharomyces cerevisiae S288C]

Protein Classification

exocyst complex component Sec6 family protein( domain architecture ID 10009113)

exocyst complex component Sec6 family protein similar to human exocyst complex component 3, which is part of the exocyst complex that is involved in the docking of exocytic vesicles with fusion sites on the plasma membrane

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
SEC6 COG5173
Exocyst complex subunit SEC6 [Intracellular trafficking and secretion];
2-805 0e+00

Exocyst complex subunit SEC6 [Intracellular trafficking and secretion];


:

Pssm-ID: 227500 [Multi-domain]  Cd Length: 742  Bit Score: 1001.77  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    2 SSDPLQQVCDLIKGDLSLERVRDIKEQLLKEksvveYQLNKESDKYYGEVEEslkLLNLSKNSVTSIKQQINEVNKLGND 81
Cdd:COG5173   1 MDKALTQLSETLRHDSDLQTVLDIIEQSTKF-----EALEHHDGNLSAEISK---CLNNILNISKRIYGLEEELKSLVEG 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121   82 NRFAINRYDILFRATKLYETVNTTSSIYDRIYNFVALMEHIERLLVAELAEDAletGCPHLLEIHFLLTSARDFQEQVVV 161
Cdd:COG5173  73 KRRNVRVLKGFFRLVKDYRSVKMTCLAHSNLCNVVEFSDRIEDILGTVLTEDI---DMPNLLAYHTKLYDARDFGEQLDM 149

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  162 MAKEATEDAQRTVMKLFSRLSGIISKFDKLLDGLTYDIVEMARAEQISLAIRLFKIYDLEEREDLRIEAIRNIIKKkeie 241
Cdd:COG5173 150 YATEISHDDYVTVNKAFSTLEKNSLDFDALVLEISEEIIENVKSGHIEAMDKIFKIVEKEEARDELTRKIRDAKSE---- 225

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  242 iekssikkLPNSkntarlQDETpkviEYPTNKGLYQEIMSgtistrTAPRGYKHFLINGINNSISEMFGEMREKYVGDQk 321
Cdd:COG5173 226 --------LPKS------QDNP----VLKEFYGMYRMYAT------RKTRKLKDFVIKSIEVSVKEKFDRLRNEYIFDN- 280

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  322 fDVLDNMDWIFNELIIVKEHIANCCPPHWNIFEVYFDQYYKELHSLITDLVESEPETIIILDILAFDKTFQDTLKQDFGF 401
Cdd:COG5173 281 -SGELNMDFIFKDLSFIRENISLSFPPFDNILTLYHNNYQECLLKLFTDEVTERLDAGEILAIIEFVGNYYNTIESKFNF 359

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  402 TKSEVKSVIGDKEKETLFKDYLNLIVVKMTEWIGNLEKAEFDVFLERSTPPHSDSDGLLFLDGTKTCFQMFTQQVEVAAG 481
Cdd:COG5173 360 IADEVGGRLLDNETGELLEKYTKLAQEKLKEWVMNLTRIEVDKFYARNEEPSRDSDGKLVLPGTVSLFQMITQQLEPIAF 439

                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  482 TNQAKILVGVVERFSDLLTKRQKNWISKISEEIKKQINYNhkydidPESITpedecPGGLVEYLIAVSNDQMKAADYAVA 561
Cdd:COG5173 440 TNRSDVVGIVFAHITRTITKYQEIWKSNLVEEMDKQFKSN------PESSS-----PAGLEEYLIAVGNDGLKIAQYITS 508

                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  562 ISSKYGKLVSKVYEKQITNHLEGTLDGFAEVAQCSSLGLITLMFDDLRKPYQEIFSKTWYMGSQAQQIADTLDEYLLDIK 641
Cdd:COG5173 509 LPSNTFELITSEYENDEVKELGKTVDGFIDILKASNTFLAEFIIYDCQPAIDKIFTDEWYGGSVTKVIVDTLQDYLSDYQ 588

                       650       660       670       680       690       700       710       720
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  642 PQMNSVLFVNFIDNVIGETIIKFLTALSFEHSFKNKNNkFLEAMKRDFEIFYQLFVKVLDGNESKDTLItqnfTVMEFFM 721
Cdd:COG5173 589 NTMSEYLFVTFIHELSMSIVIAYLKQLGRKRASIAEEN-ASRTLKSDHTKLYEMFSGYGDPEDVKTTLS----PILKIIP 663

                       730       740       750       760       770       780       790       800
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  722 DLSCEPIDSILDIWQKYLEVYWDSRIDLLVGILKCRKDVSSSerkkIVQQATEMLHEYRRNMEANgVDREPTLMRRFVLE 801
Cdd:COG5173 664 LMDTRNDDLFIVEVKSLKEIYWDIKKSLIKTILKKRQDLTES----IIQKKTLADRLKECFTDVA-TSREPTIFSRLLNL 738


                ....
gi 6322121  802 FEKQ 805
Cdd:COG5173 739 SGSS 742
 
Name Accession Description Interval E-value
SEC6 COG5173
Exocyst complex subunit SEC6 [Intracellular trafficking and secretion];
2-805 0e+00

Exocyst complex subunit SEC6 [Intracellular trafficking and secretion];


Pssm-ID: 227500 [Multi-domain]  Cd Length: 742  Bit Score: 1001.77  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    2 SSDPLQQVCDLIKGDLSLERVRDIKEQLLKEksvveYQLNKESDKYYGEVEEslkLLNLSKNSVTSIKQQINEVNKLGND 81
Cdd:COG5173   1 MDKALTQLSETLRHDSDLQTVLDIIEQSTKF-----EALEHHDGNLSAEISK---CLNNILNISKRIYGLEEELKSLVEG 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121   82 NRFAINRYDILFRATKLYETVNTTSSIYDRIYNFVALMEHIERLLVAELAEDAletGCPHLLEIHFLLTSARDFQEQVVV 161
Cdd:COG5173  73 KRRNVRVLKGFFRLVKDYRSVKMTCLAHSNLCNVVEFSDRIEDILGTVLTEDI---DMPNLLAYHTKLYDARDFGEQLDM 149

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  162 MAKEATEDAQRTVMKLFSRLSGIISKFDKLLDGLTYDIVEMARAEQISLAIRLFKIYDLEEREDLRIEAIRNIIKKkeie 241
Cdd:COG5173 150 YATEISHDDYVTVNKAFSTLEKNSLDFDALVLEISEEIIENVKSGHIEAMDKIFKIVEKEEARDELTRKIRDAKSE---- 225

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  242 iekssikkLPNSkntarlQDETpkviEYPTNKGLYQEIMSgtistrTAPRGYKHFLINGINNSISEMFGEMREKYVGDQk 321
Cdd:COG5173 226 --------LPKS------QDNP----VLKEFYGMYRMYAT------RKTRKLKDFVIKSIEVSVKEKFDRLRNEYIFDN- 280

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  322 fDVLDNMDWIFNELIIVKEHIANCCPPHWNIFEVYFDQYYKELHSLITDLVESEPETIIILDILAFDKTFQDTLKQDFGF 401
Cdd:COG5173 281 -SGELNMDFIFKDLSFIRENISLSFPPFDNILTLYHNNYQECLLKLFTDEVTERLDAGEILAIIEFVGNYYNTIESKFNF 359

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  402 TKSEVKSVIGDKEKETLFKDYLNLIVVKMTEWIGNLEKAEFDVFLERSTPPHSDSDGLLFLDGTKTCFQMFTQQVEVAAG 481
Cdd:COG5173 360 IADEVGGRLLDNETGELLEKYTKLAQEKLKEWVMNLTRIEVDKFYARNEEPSRDSDGKLVLPGTVSLFQMITQQLEPIAF 439

                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  482 TNQAKILVGVVERFSDLLTKRQKNWISKISEEIKKQINYNhkydidPESITpedecPGGLVEYLIAVSNDQMKAADYAVA 561
Cdd:COG5173 440 TNRSDVVGIVFAHITRTITKYQEIWKSNLVEEMDKQFKSN------PESSS-----PAGLEEYLIAVGNDGLKIAQYITS 508

                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  562 ISSKYGKLVSKVYEKQITNHLEGTLDGFAEVAQCSSLGLITLMFDDLRKPYQEIFSKTWYMGSQAQQIADTLDEYLLDIK 641
Cdd:COG5173 509 LPSNTFELITSEYENDEVKELGKTVDGFIDILKASNTFLAEFIIYDCQPAIDKIFTDEWYGGSVTKVIVDTLQDYLSDYQ 588

                       650       660       670       680       690       700       710       720
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  642 PQMNSVLFVNFIDNVIGETIIKFLTALSFEHSFKNKNNkFLEAMKRDFEIFYQLFVKVLDGNESKDTLItqnfTVMEFFM 721
Cdd:COG5173 589 NTMSEYLFVTFIHELSMSIVIAYLKQLGRKRASIAEEN-ASRTLKSDHTKLYEMFSGYGDPEDVKTTLS----PILKIIP 663

                       730       740       750       760       770       780       790       800
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  722 DLSCEPIDSILDIWQKYLEVYWDSRIDLLVGILKCRKDVSSSerkkIVQQATEMLHEYRRNMEANgVDREPTLMRRFVLE 801
Cdd:COG5173 664 LMDTRNDDLFIVEVKSLKEIYWDIKKSLIKTILKKRQDLTES----IIQKKTLADRLKECFTDVA-TSREPTIFSRLLNL 738


                ....
gi 6322121  802 FEKQ 805
Cdd:COG5173 739 SGSS 742
Sec6 pfam06046
Exocyst complex component Sec6; Sec6 is a component of the multiprotein exocyst complex. Sec6 ...
 178-798 0e+00

Exocyst complex component Sec6; Sec6 is a component of the multiprotein exocyst complex. Sec6 interacts with Sec8, Sec10 and Exo70.These exocyst proteins localize to regions of active exocytosis-at the growing ends of interphase cells and in the medial region of cells undergoing cytokinesis-in an F-actin-dependent and exocytosis- independent manner.


Pssm-ID: 428738  Cd Length: 570  Bit Score: 554.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    178 FSRLSGIISKFDKLLDGLTYDIVEMARAEQISLAIRLFKIYDLEEREDLRIEAIRNIIKKKEIEIEKssikklpnsknta 257
Cdd:pfam06046   1 FSKVDGLIEKFDKLLWEIIRNLLELVREGNTSLVVRLARIVEREEKEDEKAEALREATKGHKDMATR------------- 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    258 rlqdetpkvieyptnkglyqeimSGTISTRTAPRGYKHFLINGINNSISEMFGEMREKYVGDQ-KFDVLDNMDWIFNELI 336
Cdd:pfam06046  68 -----------------------FSINVFRRRPRGYKDKFLEALEESVEERFEECREKFSEDDkKLELLYNLDWVFDDLI 124

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    337 IVKEHIANCCPPHWNIFEVYFDQYYKELHSLITDLVES-EPETIIILDILAFDKTFQDTLKQ---DFGFTKSEVKSVIGD 412
Cdd:pfam06046 125 VVKDLLAPLFPPHWKIFKTYANIYHNALHDLLQELVDSeELEAADILAILSWVKTYYSKMMKgnpELEFDISDLGPLLGD 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    413 KEKETLFKDYLNLIVVKMTEWIGNLEKAEFDVFLERSTPPHSDSDGLLFLDGTKTCFQMFTQQVEVAAGTNQAKILVGVV 492
Cdd:pfam06046 205 EVLEELEDDYLSLIVNKMREWLDNLLETEVKDFTEREEPPEEDLDGYYHLPLPVDVFQMLAEQVDVAADSLQAKILVGVL 284

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    493 ERFSDLLTKRQKNWISKISEEIKKQINYNHKydidpesitpedECPGGLVEYLIAVSNDQMKAADYAVAISSKYGKlvsK 572
Cdd:pfam06046 285 EELAKFLRSRQDAWIELLEEELKKYMSVNNN------------ESPPGLVEYLIALANDQLKCADYAESLLQKYEP---L 349

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    573 VYEKQITNHLEGTLDGFAEVAQCSSLGLITLMFDDLRKPYQEIFSKTWYMGSQAQQIADTLDEYLLDIKPQMNSVLFVNF 652
Cdd:pfam06046 350 KYEERISDEFEELLDGLVDLSKECISALLDIIFNDLQPALSKLFTKKWYTGEVMEQIVETVEDYLNDYKEYLHPPLFQEL 429

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    653 IDNVIGETIIKFLTALSFEHSFK--NKNNKFLEAMKRDFEIFYQLFVKVLDgneSKDTLITQNFTVMEFF-MDLSCEPID 729
Cdd:pfam06046 430 LEELLDELVVEYLRALRGKRLKFgaEKQEQFAEKMKRDAEQLYDFFSKLGS---RDAAWLLQALRAIEDLlELLELEDPD 506

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6322121    730 SILDIWQKYLEVYWDSRIDLLVGILKCRKDVSSSERKKIVQQATEMLHEYRRnmeanGVDREPTLMRRF 798
Cdd:pfam06046 507 AVPLEYETLLSSYPDISLDHVEAVLKARGDLDKSMVKALLQQLREIKKSYES-----GVEPPRTIFSRV 570
 
Name Accession Description Interval E-value
SEC6 COG5173
Exocyst complex subunit SEC6 [Intracellular trafficking and secretion];
2-805 0e+00

Exocyst complex subunit SEC6 [Intracellular trafficking and secretion];


Pssm-ID: 227500 [Multi-domain]  Cd Length: 742  Bit Score: 1001.77  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    2 SSDPLQQVCDLIKGDLSLERVRDIKEQLLKEksvveYQLNKESDKYYGEVEEslkLLNLSKNSVTSIKQQINEVNKLGND 81
Cdd:COG5173   1 MDKALTQLSETLRHDSDLQTVLDIIEQSTKF-----EALEHHDGNLSAEISK---CLNNILNISKRIYGLEEELKSLVEG 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121   82 NRFAINRYDILFRATKLYETVNTTSSIYDRIYNFVALMEHIERLLVAELAEDAletGCPHLLEIHFLLTSARDFQEQVVV 161
Cdd:COG5173  73 KRRNVRVLKGFFRLVKDYRSVKMTCLAHSNLCNVVEFSDRIEDILGTVLTEDI---DMPNLLAYHTKLYDARDFGEQLDM 149

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  162 MAKEATEDAQRTVMKLFSRLSGIISKFDKLLDGLTYDIVEMARAEQISLAIRLFKIYDLEEREDLRIEAIRNIIKKkeie 241
Cdd:COG5173 150 YATEISHDDYVTVNKAFSTLEKNSLDFDALVLEISEEIIENVKSGHIEAMDKIFKIVEKEEARDELTRKIRDAKSE---- 225

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  242 iekssikkLPNSkntarlQDETpkviEYPTNKGLYQEIMSgtistrTAPRGYKHFLINGINNSISEMFGEMREKYVGDQk 321
Cdd:COG5173 226 --------LPKS------QDNP----VLKEFYGMYRMYAT------RKTRKLKDFVIKSIEVSVKEKFDRLRNEYIFDN- 280

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  322 fDVLDNMDWIFNELIIVKEHIANCCPPHWNIFEVYFDQYYKELHSLITDLVESEPETIIILDILAFDKTFQDTLKQDFGF 401
Cdd:COG5173 281 -SGELNMDFIFKDLSFIRENISLSFPPFDNILTLYHNNYQECLLKLFTDEVTERLDAGEILAIIEFVGNYYNTIESKFNF 359

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  402 TKSEVKSVIGDKEKETLFKDYLNLIVVKMTEWIGNLEKAEFDVFLERSTPPHSDSDGLLFLDGTKTCFQMFTQQVEVAAG 481
Cdd:COG5173 360 IADEVGGRLLDNETGELLEKYTKLAQEKLKEWVMNLTRIEVDKFYARNEEPSRDSDGKLVLPGTVSLFQMITQQLEPIAF 439

                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  482 TNQAKILVGVVERFSDLLTKRQKNWISKISEEIKKQINYNhkydidPESITpedecPGGLVEYLIAVSNDQMKAADYAVA 561
Cdd:COG5173 440 TNRSDVVGIVFAHITRTITKYQEIWKSNLVEEMDKQFKSN------PESSS-----PAGLEEYLIAVGNDGLKIAQYITS 508

                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  562 ISSKYGKLVSKVYEKQITNHLEGTLDGFAEVAQCSSLGLITLMFDDLRKPYQEIFSKTWYMGSQAQQIADTLDEYLLDIK 641
Cdd:COG5173 509 LPSNTFELITSEYENDEVKELGKTVDGFIDILKASNTFLAEFIIYDCQPAIDKIFTDEWYGGSVTKVIVDTLQDYLSDYQ 588

                       650       660       670       680       690       700       710       720
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  642 PQMNSVLFVNFIDNVIGETIIKFLTALSFEHSFKNKNNkFLEAMKRDFEIFYQLFVKVLDGNESKDTLItqnfTVMEFFM 721
Cdd:COG5173 589 NTMSEYLFVTFIHELSMSIVIAYLKQLGRKRASIAEEN-ASRTLKSDHTKLYEMFSGYGDPEDVKTTLS----PILKIIP 663

                       730       740       750       760       770       780       790       800
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121  722 DLSCEPIDSILDIWQKYLEVYWDSRIDLLVGILKCRKDVSSSerkkIVQQATEMLHEYRRNMEANgVDREPTLMRRFVLE 801
Cdd:COG5173 664 LMDTRNDDLFIVEVKSLKEIYWDIKKSLIKTILKKRQDLTES----IIQKKTLADRLKECFTDVA-TSREPTIFSRLLNL 738


                ....
gi 6322121  802 FEKQ 805
Cdd:COG5173 739 SGSS 742
Sec6 pfam06046
Exocyst complex component Sec6; Sec6 is a component of the multiprotein exocyst complex. Sec6 ...
 178-798 0e+00

Exocyst complex component Sec6; Sec6 is a component of the multiprotein exocyst complex. Sec6 interacts with Sec8, Sec10 and Exo70.These exocyst proteins localize to regions of active exocytosis-at the growing ends of interphase cells and in the medial region of cells undergoing cytokinesis-in an F-actin-dependent and exocytosis- independent manner.


Pssm-ID: 428738  Cd Length: 570  Bit Score: 554.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    178 FSRLSGIISKFDKLLDGLTYDIVEMARAEQISLAIRLFKIYDLEEREDLRIEAIRNIIKKKEIEIEKssikklpnsknta 257
Cdd:pfam06046   1 FSKVDGLIEKFDKLLWEIIRNLLELVREGNTSLVVRLARIVEREEKEDEKAEALREATKGHKDMATR------------- 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    258 rlqdetpkvieyptnkglyqeimSGTISTRTAPRGYKHFLINGINNSISEMFGEMREKYVGDQ-KFDVLDNMDWIFNELI 336
Cdd:pfam06046  68 -----------------------FSINVFRRRPRGYKDKFLEALEESVEERFEECREKFSEDDkKLELLYNLDWVFDDLI 124

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    337 IVKEHIANCCPPHWNIFEVYFDQYYKELHSLITDLVES-EPETIIILDILAFDKTFQDTLKQ---DFGFTKSEVKSVIGD 412
Cdd:pfam06046 125 VVKDLLAPLFPPHWKIFKTYANIYHNALHDLLQELVDSeELEAADILAILSWVKTYYSKMMKgnpELEFDISDLGPLLGD 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    413 KEKETLFKDYLNLIVVKMTEWIGNLEKAEFDVFLERSTPPHSDSDGLLFLDGTKTCFQMFTQQVEVAAGTNQAKILVGVV 492
Cdd:pfam06046 205 EVLEELEDDYLSLIVNKMREWLDNLLETEVKDFTEREEPPEEDLDGYYHLPLPVDVFQMLAEQVDVAADSLQAKILVGVL 284

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    493 ERFSDLLTKRQKNWISKISEEIKKQINYNHKydidpesitpedECPGGLVEYLIAVSNDQMKAADYAVAISSKYGKlvsK 572
Cdd:pfam06046 285 EELAKFLRSRQDAWIELLEEELKKYMSVNNN------------ESPPGLVEYLIALANDQLKCADYAESLLQKYEP---L 349

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    573 VYEKQITNHLEGTLDGFAEVAQCSSLGLITLMFDDLRKPYQEIFSKTWYMGSQAQQIADTLDEYLLDIKPQMNSVLFVNF 652
Cdd:pfam06046 350 KYEERISDEFEELLDGLVDLSKECISALLDIIFNDLQPALSKLFTKKWYTGEVMEQIVETVEDYLNDYKEYLHPPLFQEL 429

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322121    653 IDNVIGETIIKFLTALSFEHSFK--NKNNKFLEAMKRDFEIFYQLFVKVLDgneSKDTLITQNFTVMEFF-MDLSCEPID 729
Cdd:pfam06046 430 LEELLDELVVEYLRALRGKRLKFgaEKQEQFAEKMKRDAEQLYDFFSKLGS---RDAAWLLQALRAIEDLlELLELEDPD 506

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6322121    730 SILDIWQKYLEVYWDSRIDLLVGILKCRKDVSSSERKKIVQQATEMLHEYRRnmeanGVDREPTLMRRF 798
Cdd:pfam06046 507 AVPLEYETLLSSYPDISLDHVEAVLKARGDLDKSMVKALLQQLREIKKSYES-----GVEPPRTIFSRV 570
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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