|
Name |
Accession |
Description |
Interval |
E-value |
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
1-422 |
5.97e-115 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 338.57 E-value: 5.97e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 1 MRKCKIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGG 80
Cdd:COG0462 1 MKDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 81 SARKITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENve 160
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSK-- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 161 DYEDAVVVSKNPGGTKRVTALADSLKINFAMIhtDRRRSKdlysqnkdlqqlklrkqsmlrknrpiirqgdhPNEeenii 240
Cdd:COG0462 159 DLEDLVVVSPDVGGVKRARAFAKRLGAPLAII--DKRRPG--------------------------------ANE----- 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 241 lsngiqtARIRNghvigddeadddedailesdselhsidgldshglggtydavdsedeeeipvlyreqlitLVGNVRGRS 320
Cdd:COG0462 200 -------VEVMN-----------------------------------------------------------IIGDVEGKT 213
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 321 AIILDDMIDRPGSFISAAEHLVQNcGAKKVYVVATHGIFTGDCLEELEKSdAIDTIVVTNTYPISGEriAGSKKLVTIDV 400
Cdd:COG0462 214 CIIVDDMIDTGGTLVEAAEALKEA-GAKSVYAAATHGVLSGPAVERLENS-PIDELVVTDTIPLPEE--KRCDKIKVLSV 289
|
410 420
....*....|....*....|..
gi 6322667 401 SPIFAECIRRDHYGESISVLFD 422
Cdd:COG0462 290 APLLAEAIRRIHEGESVSSLFD 311
|
|
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
5-422 |
3.41e-100 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 300.88 E-value: 3.41e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 5 KIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGSARK 84
Cdd:PRK01259 2 KLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAGR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 85 ITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENveDYED 164
Cdd:PRK01259 82 ITAVIPYFGYARQDRKARSRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQK--NLEN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 165 AVVVSKNPGGTKRVTALADSLKINFAMIhtDRRRSKdlysqnkdlqqlklrkqsmlrknrpiirqgdhPNEEE--NIIls 242
Cdd:PRK01259 160 LVVVSPDVGGVVRARALAKRLDADLAII--DKRRPR--------------------------------ANVSEvmNII-- 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 243 ngiqtarirnghvigddeadddedailesdselhsidgldshglggtydavdsedeeeipvlyreqlitlvGNVRGRSAI 322
Cdd:PRK01259 204 -----------------------------------------------------------------------GDVEGRDCI 212
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 323 ILDDMIDRPGSFISAAEHLVQNcGAKKVYVVATHGIFTGDCLEELEKSdAIDTIVVTNTYPISgERIAGSKKLVTIDVSP 402
Cdd:PRK01259 213 LVDDMIDTAGTLCKAAEALKER-GAKSVYAYATHPVLSGGAIERIENS-VIDELVVTDSIPLS-EEAKKCDKIRVLSVAP 289
|
410 420
....*....|....*....|
gi 6322667 403 IFAECIRRDHYGESISVLFD 422
Cdd:PRK01259 290 LLAEAIRRISNEESVSSLFD 309
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
5-422 |
1.72e-89 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 273.77 E-value: 1.72e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 5 KIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVI-QSGSPSINDDIMELLILVSACRGGSAR 83
Cdd:TIGR01251 2 KIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASAK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 84 KITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVEDye 163
Cdd:TIGR01251 82 SITAVIPYYGYARQDKKFKSREPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKILD-- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 164 DAVVVSKNPGGTKRVTALADSLKINFAMIHtdrrrskdlysqnkdlqqlklrkqsmlrKNRPiirqgdhpneeeniilsn 243
Cdd:TIGR01251 160 NPVVVSPDAGGVERAKKVADALGCPLAIID----------------------------KRRI------------------ 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 244 giqtarirnghvigddeadddedailesdselhsidgldshglggtydavDSEDEEEIpvlyreqlITLVGNVRGRSAII 323
Cdd:TIGR01251 194 --------------------------------------------------SATNEVEV--------MNLVGDVEGKDVVI 215
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 324 LDDMIDRPGSFISAAEHLVqNCGAKKVYVVATHGIFTGDCLEELEKSDaIDTIVVTNTYPISGERiagsKKLVTIDVSPI 403
Cdd:TIGR01251 216 VDDIIDTGGTIAKAAEILK-SAGAKRVIAAATHGVFSGPAIERIANAG-VEEVIVTNTIPHEKHK----PKVSVISVAPL 289
|
410
....*....|....*....
gi 6322667 404 FAECIRRDHYGESISVLFD 422
Cdd:TIGR01251 290 IAEAIRRIHNNESVSSLFD 308
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
5-120 |
1.96e-59 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 189.55 E-value: 1.96e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 5 KIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGSARK 84
Cdd:pfam13793 2 KIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAKR 81
|
90 100 110
....*....|....*....|....*....|....*.
gi 6322667 85 ITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAG 120
Cdd:pfam13793 82 ITAVIPYFGYARQDRKDKPREPITAKLVADLLEAAG 117
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
283-381 |
8.98e-11 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 59.33 E-value: 8.98e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 283 SHGLGGTYDAVDSE--DEEEIPVLYREQLITLVGNVRGRSAIILDDMIDRPGSFISAAEHLvQNCGAKKVYVVATHGIFT 360
Cdd:cd06223 34 ARALGLPLAFIRKErkGPGRTPSEPYGLELPLGGDVKGKRVLLVDDVIATGGTLLAAIELL-KEAGAKVVGVAVLLDKPE 112
|
90 100
....*....|....*....|.
gi 6322667 361 GDcleELEKSDAIDTIVVTNT 381
Cdd:cd06223 113 GG---ARELASPGDPVYSLFT 130
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
1-422 |
5.97e-115 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 338.57 E-value: 5.97e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 1 MRKCKIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGG 80
Cdd:COG0462 1 MKDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 81 SARKITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENve 160
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSK-- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 161 DYEDAVVVSKNPGGTKRVTALADSLKINFAMIhtDRRRSKdlysqnkdlqqlklrkqsmlrknrpiirqgdhPNEeenii 240
Cdd:COG0462 159 DLEDLVVVSPDVGGVKRARAFAKRLGAPLAII--DKRRPG--------------------------------ANE----- 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 241 lsngiqtARIRNghvigddeadddedailesdselhsidgldshglggtydavdsedeeeipvlyreqlitLVGNVRGRS 320
Cdd:COG0462 200 -------VEVMN-----------------------------------------------------------IIGDVEGKT 213
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 321 AIILDDMIDRPGSFISAAEHLVQNcGAKKVYVVATHGIFTGDCLEELEKSdAIDTIVVTNTYPISGEriAGSKKLVTIDV 400
Cdd:COG0462 214 CIIVDDMIDTGGTLVEAAEALKEA-GAKSVYAAATHGVLSGPAVERLENS-PIDELVVTDTIPLPEE--KRCDKIKVLSV 289
|
410 420
....*....|....*....|..
gi 6322667 401 SPIFAECIRRDHYGESISVLFD 422
Cdd:COG0462 290 APLLAEAIRRIHEGESVSSLFD 311
|
|
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
5-422 |
3.41e-100 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 300.88 E-value: 3.41e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 5 KIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGSARK 84
Cdd:PRK01259 2 KLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAGR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 85 ITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENveDYED 164
Cdd:PRK01259 82 ITAVIPYFGYARQDRKARSRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQK--NLEN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 165 AVVVSKNPGGTKRVTALADSLKINFAMIhtDRRRSKdlysqnkdlqqlklrkqsmlrknrpiirqgdhPNEEE--NIIls 242
Cdd:PRK01259 160 LVVVSPDVGGVVRARALAKRLDADLAII--DKRRPR--------------------------------ANVSEvmNII-- 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 243 ngiqtarirnghvigddeadddedailesdselhsidgldshglggtydavdsedeeeipvlyreqlitlvGNVRGRSAI 322
Cdd:PRK01259 204 -----------------------------------------------------------------------GDVEGRDCI 212
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 323 ILDDMIDRPGSFISAAEHLVQNcGAKKVYVVATHGIFTGDCLEELEKSdAIDTIVVTNTYPISgERIAGSKKLVTIDVSP 402
Cdd:PRK01259 213 LVDDMIDTAGTLCKAAEALKER-GAKSVYAYATHPVLSGGAIERIENS-VIDELVVTDSIPLS-EEAKKCDKIRVLSVAP 289
|
410 420
....*....|....*....|
gi 6322667 403 IFAECIRRDHYGESISVLFD 422
Cdd:PRK01259 290 LLAEAIRRISNEESVSSLFD 309
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
5-422 |
1.72e-89 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 273.77 E-value: 1.72e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 5 KIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVI-QSGSPSINDDIMELLILVSACRGGSAR 83
Cdd:TIGR01251 2 KIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASAK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 84 KITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVEDye 163
Cdd:TIGR01251 82 SITAVIPYYGYARQDKKFKSREPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKILD-- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 164 DAVVVSKNPGGTKRVTALADSLKINFAMIHtdrrrskdlysqnkdlqqlklrkqsmlrKNRPiirqgdhpneeeniilsn 243
Cdd:TIGR01251 160 NPVVVSPDAGGVERAKKVADALGCPLAIID----------------------------KRRI------------------ 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 244 giqtarirnghvigddeadddedailesdselhsidgldshglggtydavDSEDEEEIpvlyreqlITLVGNVRGRSAII 323
Cdd:TIGR01251 194 --------------------------------------------------SATNEVEV--------MNLVGDVEGKDVVI 215
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 324 LDDMIDRPGSFISAAEHLVqNCGAKKVYVVATHGIFTGDCLEELEKSDaIDTIVVTNTYPISGERiagsKKLVTIDVSPI 403
Cdd:TIGR01251 216 VDDIIDTGGTIAKAAEILK-SAGAKRVIAAATHGVFSGPAIERIANAG-VEEVIVTNTIPHEKHK----PKVSVISVAPL 289
|
410
....*....|....*....
gi 6322667 404 FAECIRRDHYGESISVLFD 422
Cdd:TIGR01251 290 IAEAIRRIHNNESVSSLFD 308
|
|
| PRK03092 |
PRK03092 |
ribose-phosphate diphosphokinase; |
15-425 |
7.39e-70 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179535 [Multi-domain] Cd Length: 304 Bit Score: 222.90 E-value: 7.39e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 15 LGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGSARKITAVIPQFPY 94
Cdd:PRK03092 1 LAEEVAKELGVEVTPTTAYDFANGEIYVRFEESVRGCDAFVLQSHTAPINKWLMEQLIMIDALKRASAKRITVVLPFYPY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 95 SKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVEDyEDAVVVSKNPGG 174
Cdd:PRK03092 81 ARQDKKHRGREPISARLVADLFKTAGADRIMTVDLHTAQIQGFFDGPVDHLFAMPLLADYVRDKYDL-DNVTVVSPDAGR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 175 TKRVTALADSL-KINFAMIHtdrrrskdlysqnkdlqqlklrkqsmlrKNRPIIRqgdhPNEeeniILSNGIqtarirng 253
Cdd:PRK03092 160 VRVAEQWADRLgGAPLAFIH----------------------------KTRDPTV----PNQ----VVANRV-------- 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 254 hvigddeadddedailesdselhsidgldshglggtydavdsedeeeipvlyreqlitlVGNVRGRSAIILDDMIDRPGS 333
Cdd:PRK03092 196 -----------------------------------------------------------VGDVEGRTCVLVDDMIDTGGT 216
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 334 FISAAEHLVQNcGAKKVYVVATHGIFTGDCLEELeKSDAIDTIVVTNTYPISGERiaGSKKLVTIDVSPIFAECIRRDHY 413
Cdd:PRK03092 217 IAGAVRALKEA-GAKDVIIAATHGVLSGPAAERL-KNCGAREVVVTDTLPIPEEK--RFDKLTVLSIAPLLARAIREVFE 292
|
410
....*....|..
gi 6322667 414 GESISVLFDSLA 425
Cdd:PRK03092 293 DGSVTSLFDGLA 304
|
|
| PLN02369 |
PLN02369 |
ribose-phosphate pyrophosphokinase |
13-422 |
5.40e-68 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 215209 [Multi-domain] Cd Length: 302 Bit Score: 218.02 E-value: 5.40e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 13 PELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGSARKITAVIPQF 92
Cdd:PLN02369 1 PALSQEIACYLGLELGKITIKRFADGEIYVQLQESVRGCDVFLVQPTCPPANENLMELLIMIDACRRASAKRITAVIPYF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 93 PYSKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVEDYEDAVVVSKNP 172
Cdd:PLN02369 81 GYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKTISSPDLVVVSPDV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 173 GGTKRVTALADSLK-INFAMIhtDRRrskdlysqnkdlqqlklrkqsmlrknrpiirqgdhpneeeniilsngiqtariR 251
Cdd:PLN02369 161 GGVARARAFAKKLSdAPLAIV--DKR-----------------------------------------------------R 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 252 NGHvigddeadddedailesdselhsidgldshglgGTYDAVDsedeeeipvlyreqlitLVGNVRGRSAIILDDMIDRP 331
Cdd:PLN02369 186 QGH---------------------------------NVAEVMN-----------------LIGDVKGKVAIMVDDMIDTA 215
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 332 GSFISAAEHLVQNcGAKKVYVVATHGIFTGDCLEELEkSDAIDTIVVTNTYPISGERIAgsKKLVTIDVSPIFAECIRRD 411
Cdd:PLN02369 216 GTITKGAALLHQE-GAREVYACATHAVFSPPAIERLS-SGLFQEVIVTNTIPVSEKNYF--PQLTVLSVANLLGETIWRV 291
|
410
....*....|.
gi 6322667 412 HYGESISVLFD 422
Cdd:PLN02369 292 HDDCSVSSIFD 302
|
|
| PRK02269 |
PRK02269 |
ribose-phosphate diphosphokinase; |
2-423 |
3.11e-67 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 167353 [Multi-domain] Cd Length: 320 Bit Score: 216.97 E-value: 3.11e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 2 RKCKIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGS 81
Cdd:PRK02269 4 SDLKLFALSSNKELAEKVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRAS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 82 ARKITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVED 161
Cdd:PRK02269 84 AESINVVMPYYGYARQDRKARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRRGLV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 162 YEDAVVVSKNPGGTKRVTALADSLKINFAMIhtDRRRSKDLysqnkdlqqlklrkqsmlrknrpiirqgDHPNEEENIIl 241
Cdd:PRK02269 164 GDDVVVVSPDHGGVTRARKLAQFLKTPIAII--DKRRSVDK----------------------------MNTSEVMNII- 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 242 sngiqtarirnghvigddeadddedailesdselhsidgldshglggtydavdsedeeeipvlyreqlitlvGNVRGRSA 321
Cdd:PRK02269 213 ------------------------------------------------------------------------GNVKGKKC 220
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 322 IILDDMIDRPGSFISAAEHLvQNCGAKKVYVVATHGIFTGDCLEELEKSdAIDTIVVTNTYPISGERIagSKKLVTIDVS 401
Cdd:PRK02269 221 ILIDDMIDTAGTICHAADAL-AEAGATEVYASCTHPVLSGPALDNIQKS-AIEKLVVLDTIYLPEERL--IDKIEQISIA 296
|
410 420
....*....|....*....|..
gi 6322667 402 PIFAECIRRDHYGESISVLFDS 423
Cdd:PRK02269 297 DLLGEAIIRIHEKRPLSPLFEM 318
|
|
| PRK02812 |
PRK02812 |
ribose-phosphate pyrophosphokinase; Provisional |
2-421 |
2.36e-66 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235072 [Multi-domain] Cd Length: 330 Bit Score: 214.99 E-value: 2.36e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 2 RKCKIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGS 81
Cdd:PRK02812 20 NRLRLFSGSSNPALAQEVARYLGMDLGPMIRKRFADGELYVQIQESIRGCDVYLIQPTCAPVNDHLMELLIMVDACRRAS 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 82 ARKITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIREnvED 161
Cdd:PRK02812 100 ARQITAVIPYYGYARADRKTAGRESITAKLVANLITKAGADRVLAMDLHSAQIQGYFDIPCDHVYGSPVLLDYLAS--KN 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 162 YEDAVVVSKNPGGTKRVTALADSLK-INFAMIhtDRRRSkdlysqnkdlqqlklrkqsmlrknrpiirqgdhpneeenii 240
Cdd:PRK02812 178 LEDIVVVSPDVGGVARARAFAKKLNdAPLAII--DKRRQ----------------------------------------- 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 241 lsngiqtarirnghvigddeadddedailesdselhsidgldSHGLGgtydavdsedeeeipvlyreQLITLVGNVRGRS 320
Cdd:PRK02812 215 ------------------------------------------AHNVA--------------------EVLNVIGDVKGKT 232
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 321 AIILDDMIDRPGSfISAAEHLVQNCGAKKVYVVATHGIFTGDCLEELEkSDAIDTIVVTNTYPISGERiaGSKKLVTIDV 400
Cdd:PRK02812 233 AILVDDMIDTGGT-ICEGARLLRKEGAKQVYACATHAVFSPPAIERLS-SGLFEEVIVTNTIPVPEER--RFPQLKVLSV 308
|
410 420
....*....|....*....|.
gi 6322667 401 SPIFAECIRRDHYGESISVLF 421
Cdd:PRK02812 309 ANMLGEAIWRIHEESSVSSMF 329
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
5-120 |
1.96e-59 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 189.55 E-value: 1.96e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 5 KIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGSARK 84
Cdd:pfam13793 2 KIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAKR 81
|
90 100 110
....*....|....*....|....*....|....*.
gi 6322667 85 ITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAG 120
Cdd:pfam13793 82 ITAVIPYFGYARQDRKDKPREPITAKLVADLLEAAG 117
|
|
| PTZ00145 |
PTZ00145 |
phosphoribosylpyrophosphate synthetase; Provisional |
1-422 |
7.47e-56 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 240290 [Multi-domain] Cd Length: 439 Bit Score: 190.85 E-value: 7.47e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 1 MRKCKIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGG 80
Cdd:PTZ00145 117 MENAILFSGSSNPLLSKNIADHLGTILGRVHLKRFADGEVSMQFLESIRGKDVYIIQPTCPPVNENLIELLLMISTCRRA 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 81 SARKITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTK--PVDNLYggpslAKWIREN 158
Cdd:PTZ00145 197 SAKKITAVIPYYGYARQDRKLSSRVPISAADVARMIEAMGVDRVVAIDLHSGQIQGFFGPrvPVDNLE-----AQLIGLD 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 159 V---EDYEDAVVVSKNPGGTKRVTALADSLkinfamihtdrrrskdlysQNKDLQQLKLrkqSMLrknrpiIRQGDHPNE 235
Cdd:PTZ00145 272 YftkKDLYKPVIVSPDAGGVYRARKFQDGL-------------------NHRGISDCGI---AML------IKQRTKPNE 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 236 eeniilsngiqtarirnghvigddeadddedailesdselhsIDGLDshglggtydavdsedeeeipvlyreqlitLVGN 315
Cdd:PTZ00145 324 ------------------------------------------IEKMD-----------------------------LVGN 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 316 VRGRSAIILDDMIDRPGSFISAAEHLVQNcGAKKVYVVATHGIFTGDCLEELEKSdAIDTIVVTNTYPiSGERIAGSKKL 395
Cdd:PTZ00145 333 VYDSDVIIVDDMIDTSGTLCEAAKQLKKH-GARRVFAFATHGLFSGPAIERIEAS-PLEEVVVTDTVK-SNKNIDSCKKI 409
|
410 420
....*....|....*....|....*..
gi 6322667 396 VTIDVSPIFAECIRRDHYGESISVLFD 422
Cdd:PTZ00145 410 TKLSVSVLVADAIRRIHQKESLNDLFN 436
|
|
| PRK02458 |
PRK02458 |
ribose-phosphate pyrophosphokinase; Provisional |
5-421 |
3.11e-55 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235039 [Multi-domain] Cd Length: 323 Bit Score: 185.71 E-value: 3.11e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 5 KIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGSARK 84
Cdd:PRK02458 11 KLFSLNSNLEIAEKIAQAAGVPLGKLSSRQFSDGEIMINIEESVRGDDIYIIQSTSFPVNDHLWELLIMIDACKRASANT 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 85 ITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVEDYED 164
Cdd:PRK02458 91 VNVVLPYFGYARQDRIAKPREPITAKLVANMLVKAGVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCKKGLSGSD 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 165 AVVVSKNPGGTKRVTALADSLkinfamihtdrrrskdlysqnkdlqqlklrkqsmlrknrpiirqgdhpneeeniilsng 244
Cdd:PRK02458 171 VVVVSPKNSGIKRARSLAEYL----------------------------------------------------------- 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 245 iqtarirnghvigddeadddedailesDSELHSIDgldshglggtYDAVDSEDEEEIpvlyreqlitLVGNVRGRSAIIL 324
Cdd:PRK02458 192 ---------------------------DAPIAIID----------YAQDDSEREEGY----------IIGDVAGKKAILI 224
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 325 DDMIDRPGSFISAAEhLVQNCGAKKVYVVATHGIFTGDCLEELEKSDaIDTIVVTNTYpISGERIagSKKLVTIDVSPIF 404
Cdd:PRK02458 225 DDILNTGKTFAEAAK-IVEREGATEIYAVASHGLFAGGAAEVLENAP-IKEILVTDSV-ATKERV--PKNVTYLSASELI 299
|
410
....*....|....*..
gi 6322667 405 AECIRRDHYGESISVLF 421
Cdd:PRK02458 300 ADAIIRIHERKPLSPLF 316
|
|
| PRK04923 |
PRK04923 |
ribose-phosphate diphosphokinase; |
2-421 |
6.84e-55 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179893 [Multi-domain] Cd Length: 319 Bit Score: 184.75 E-value: 6.84e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 2 RKCKIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGS 81
Cdd:PRK04923 5 RNLLVFSGNANKPLAQSICKELGVRMGKALVTRFSDGEVQVEIEESVRRQEVFVIQPTCAPSAENLMELLVLIDALKRAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 82 ARKITAVIPQFPYSKQ-CKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVE 160
Cdd:PRK04923 85 AASVTAVIPYFGYSRQdRRMRSSRVPITAKVAAKMISAMGADRVLTVDLHADQIQGFFDVPVDNVYASPLLLADIWRAYG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 161 dYEDAVVVSKNPGGTKRVTALADSL-KINFAMIhtDRRRskdlysqnkdlqqlklrkqsmlrknrpiirqgdhpneeeni 239
Cdd:PRK04923 165 -TDNLIVVSPDVGGVVRARAVAKRLdDADLAII--DKRR----------------------------------------- 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 240 ilsngiqtarirnghvigddeadddedailesdselhsidgldshglggtydavdsedeeeiPVLYREQLITLVGNVRGR 319
Cdd:PRK04923 201 --------------------------------------------------------------PRANVATVMNIIGDVQGK 218
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 320 SAIILDDMIDRPGSFISAAEHLVQNcGAKKVYVVATHGIFTGDCLEELEKSDaIDTIVVTNTYPISgERIAGSKKLVTID 399
Cdd:PRK04923 219 TCVLVDDLVDTAGTLCAAAAALKQR-GALKVVAYITHPVLSGPAVDNINNSQ-LDELVVTDTIPLS-EAARACAKIRQLS 295
|
410 420
....*....|....*....|..
gi 6322667 400 VSPIFAECIRRDHYGESISVLF 421
Cdd:PRK04923 296 VAELLAETIRRIAFGESVSSLY 317
|
|
| PRK00553 |
PRK00553 |
ribose-phosphate pyrophosphokinase; Provisional |
6-421 |
4.11e-50 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 179062 [Multi-domain] Cd Length: 332 Bit Score: 172.41 E-value: 4.11e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 6 IFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGSARKI 85
Cdd:PRK00553 12 IFSLSKAKKLVDSICRKLSMKPGEIVIQKFADGETYIRFDESVRNKDVVIFQSTCSPVNDSLMELLIAIDALKRGSAKSI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 86 TAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVEDyEDA 165
Cdd:PRK00553 92 TAILPYYGYARQDRKTAGREPITSKLVADLLTKAGVTRVTLTDIHSDQTQGFFDIPVDILRTYHVFLSRVLELLGK-KDL 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 166 VVVSKNPGGTKRVTALADSLKINFAMIhtDRRRSKdlysqnkdlqqlklrkqsmlrknrpiirqgdhPNEEENiilsngi 245
Cdd:PRK00553 171 VVVSPDYGGVKRARLIAESLELPLAII--DKRRPK--------------------------------HNVAES------- 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 246 qtarirnghvigddeadddedailesdselhsidgldshglggtydavdsedeeeipvlyreqlITLVGNVRGRSAIILD 325
Cdd:PRK00553 210 ----------------------------------------------------------------INVLGEVKNKNCLIVD 225
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 326 DMIDRPGSFISAAEhLVQNCGAKKVYVVATHGIFTGDCLEELEKS---DAIDTIVVTNTYPISgeRIAGSKKLVTIDVSP 402
Cdd:PRK00553 226 DMIDTGGTVIAAAK-LLKKQKAKKVCVMATHGLFNKNAIQLFDEAfkkKLIDKLFVSNSIPQT--KFEKKPQFKVVDLAH 302
|
410
....*....|....*....
gi 6322667 403 IFAECIRRDHYGESISVLF 421
Cdd:PRK00553 303 LYEEVLLCYANGGSISAIY 321
|
|
| PRK00934 |
PRK00934 |
ribose-phosphate pyrophosphokinase; Provisional |
5-410 |
8.81e-37 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 234868 [Multi-domain] Cd Length: 285 Bit Score: 135.81 E-value: 8.81e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 5 KIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSiNDDIMELLILVSACRGGSARK 84
Cdd:PRK00934 1 MIIGGSASQLLASEVARLLNTELALVETKRFPDGELYVRILGEIDGEDVVIISTTYPQ-DENLVELLLLIDALRDEGAKS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 85 ITAVIPQFPYSKQCKMKRHRGAITARMLANLLvMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRenvEDYED 164
Cdd:PRK00934 80 ITLVIPYLGYARQDKRFKPGEPISARAIAKII-SAYYDRIITINIHEPSILEFFPIPFINLDAAPLIAEYIG---DKLDD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 165 AVVVSKNPGGTKRVTALADSLKINFamihtdrrrskdlysqnkdlqqlklrkqsmlrknrpiirqgDHpneeeniilsng 244
Cdd:PRK00934 156 PLVLAPDKGALELAKEAAEILGCEY-----------------------------------------DY------------ 182
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 245 IQTARIrnghvigddeadddedailesdselhsidgldshglggtydavdSEDEEEIpvlyREQLItlvgNVRGRSAIIL 324
Cdd:PRK00934 183 LEKTRI--------------------------------------------SPTEVEI----APKNL----DVKGKDVLIV 210
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 325 DDMIDRPGSFISAAEhLVQNCGAKKVYVVATHGIFTGDCLEELEKSDAiDTIVVTNTYPisgeriagsKKLVTIDVSPIF 404
Cdd:PRK00934 211 DDIISTGGTMATAIK-ILKEQGAKKVYVACVHPVLVGDAILKLYNAGV-DEIIVTDTLE---------SEVSKISVAPLI 279
|
....*.
gi 6322667 405 AECIRR 410
Cdd:PRK00934 280 ADLLKK 285
|
|
| Pribosyl_synth |
pfam14572 |
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ... |
161-421 |
1.73e-33 |
|
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.
Pssm-ID: 434046 Cd Length: 184 Bit Score: 123.77 E-value: 1.73e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 161 DYEDAVVVSKNPGGTKRVTALADSLKINFAMIHTDrrrSKDLYSQNKDlqqlklrkqsmlrknrpiirqGDHPNEEENii 240
Cdd:pfam14572 1 DYRNAVIVARSPGSAKRATSFAERLRLGIAVIHGE---QKEAESDEVD---------------------GRQSPPPYR-- 54
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 241 lsngiqtarirnghvigddeadddedailesDSELHSIDGLDSHglggtydavdsEDEEEIPvlyreqlITLVGNVRGRS 320
Cdd:pfam14572 55 -------------------------------SRTVSRSLGLPEI-----------IPKEKPP-------MTVVGDVGGRI 85
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 321 AIILDDMIDRPGSFISAAEHLVQNcGAKKVYVVATHGIFTGDCLEELEKSdAIDTIVVTNTYPISGERiAGSKKLVTIDV 400
Cdd:pfam14572 86 AIIVDDMIDDVDSFVAAAELLKER-GAYKIYVMATHGLLSSDAPRLLEAS-PIDEVVVTNTIPHEIQK-MQCHKIKTIDI 162
|
250 260
....*....|....*....|.
gi 6322667 401 SPIFAECIRRDHYGESISVLF 421
Cdd:pfam14572 163 SQLIAEAIRRIHNGESMSYLF 183
|
|
| PRK06827 |
PRK06827 |
phosphoribosylpyrophosphate synthetase; Provisional |
29-422 |
8.40e-29 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 180714 [Multi-domain] Cd Length: 382 Bit Score: 116.20 E-value: 8.40e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 29 PCTLKKFANGETSVQIGVSVRDEDVYVIQ--SGSP------------SINDDIMELLILVSACRGGsARKITAVIPQFPY 94
Cdd:PRK06827 56 PAKFIRFSNGEAKGEILESVRGKDIYILQdvGNYSvtynmfgeknhmSPDDHFQDLKRTIDAIRGK-ARRITVIMPFLYE 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 95 SKQCKmKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTK-PVDNLYGGPSLAKWIRENVE----DYEDAVVVS 169
Cdd:PRK06827 135 SRQHK-RKGRESLDCALALQELEELGVDNIITFDAHDPRIENAIPLmGFENLYPSYQIIKALLKNEKdleiDKDHLMVIS 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 170 KNPGGTKRVTALADSLKINFAMIHtdRRRSkdlYSQnkdlqqlklrkqsmlrknrpiIRQGDHPneeenIIlsngiqtar 249
Cdd:PRK06827 214 PDTGAMDRAKYYASVLGVDLGLFY--KRRD---YSR---------------------VVNGRNP-----IV--------- 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 250 irnghvigddeadddedailesdselhsidgldSHGLGGTydavdsedeeeipvlyreqlitlvgNVRGRSAIILDDMID 329
Cdd:PRK06827 254 ---------------------------------AHEFLGR-------------------------DVEGKDVLIVDDMIA 275
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 330 RPGSFISAAEHLvQNCGAKKVYVVATHGIFTgDCLEELEKSDA---IDTIVVTN-TYpiSGERIAGSKKLVTIDVSPIFA 405
Cdd:PRK06827 276 SGGSMIDAAKEL-KSRGAKKIIVAATFGFFT-NGLEKFDKAYEegyFDRIIGTNlVY--HPEELLSKPWYIEVDMSKLIA 351
|
410
....*....|....*..
gi 6322667 406 ECIRRDHYGESISVLFD 422
Cdd:PRK06827 352 RIIDALNHDVSLSKLLD 368
|
|
| PRK07199 |
PRK07199 |
ribose-phosphate diphosphokinase; |
21-410 |
4.13e-17 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 235960 [Multi-domain] Cd Length: 301 Bit Score: 81.52 E-value: 4.13e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 21 QRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQS-GSPsiNDDIMELLILVSACRGGSARKITAVIPQFPYSKQCK 99
Cdd:PRK07199 20 AALGVEVGRIELHRFPDGESYVRLDSPVAGRTVVLVCSlDRP--DEKLLPLLFAAEAARELGARRVGLVAPYLAYMRQDI 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 100 mKRHRG-AITARMLANLLVmAGADHVVSMD--LH-ASQMQGFFTKPVDNLYGGPSLAKWIRENVEDyedAVVVSKNPGGT 175
Cdd:PRK07199 98 -AFHPGeAISQRHFARLLS-GSFDRLVTVDphLHrYPSLSEVYPIPAVVLSAAPAIAAWIRAHVPR---PLLIGPDEESE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 176 KRVTALAdslkinfAMIHTDRrrskdlysqnkdlqqlklrkqSMLRKnrpiIRQGDHpneeeniilsngiqtarirnghv 255
Cdd:PRK07199 173 QWVAAVA-------ERAGAPH---------------------AVLRK----TRHGDR----------------------- 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 256 igddeadddedailesdselhsidgldshglggtydavdsedEEEIPVLYREQLitlvgnvRGRSAIILDDMIDRPGSFI 335
Cdd:PRK07199 198 ------------------------------------------DVEISLPDAAPW-------AGRTPVLVDDIVSTGRTLI 228
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6322667 336 SAAEHLVQnCGAKKVYVVATHGIFTGDCLEELEKSdAIDTIVVTNTYPISGERiagskklvtIDVSPIFAECIRR 410
Cdd:PRK07199 229 EAARQLRA-AGAASPDCVVVHALFAGDAYSALAAA-GIARVVSTDTVPHPSNA---------ISLAPLLAEALRR 292
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
283-381 |
8.98e-11 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 59.33 E-value: 8.98e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 283 SHGLGGTYDAVDSE--DEEEIPVLYREQLITLVGNVRGRSAIILDDMIDRPGSFISAAEHLvQNCGAKKVYVVATHGIFT 360
Cdd:cd06223 34 ARALGLPLAFIRKErkGPGRTPSEPYGLELPLGGDVKGKRVLLVDDVIATGGTLLAAIELL-KEAGAKVVGVAVLLDKPE 112
|
90 100
....*....|....*....|.
gi 6322667 361 GDcleELEKSDAIDTIVVTNT 381
Cdd:cd06223 113 GG---ARELASPGDPVYSLFT 130
|
|
| PLN02297 |
PLN02297 |
ribose-phosphate pyrophosphokinase |
314-391 |
1.11e-03 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 177934 [Multi-domain] Cd Length: 326 Bit Score: 40.83 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6322667 314 GNVRGRSAIILDDMIDRPGSFISAAEhLVQNCGAKKVYVVATHGIFTGDCLEELEK-----SDAIDTIVVTNTYPISGER 388
Cdd:PLN02297 226 GNPAGRHVVIVDDLVQSGGTLIECQK-VLAAHGAAKVSAYVTHGVFPNESWERFTHdnggpEAGFAYFWITDSCPQTVKA 304
|
...
gi 6322667 389 IAG 391
Cdd:PLN02297 305 VRG 307
|
|
| |
