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Conserved domains on  [gi|398364905|ref|NP_012935|]
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Tof2p [Saccharomyces cerevisiae S288C]

Protein Classification

Cytokin_check_N domain-containing protein( domain architecture ID 10564221)

Cytokin_check_N domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cytokin_check_N pfam10407
Cdc14 phosphatase binding protein N-terminus; Cytokinesis in yeasts involves a family of ...
 83-153 5.73e-26

Cdc14 phosphatase binding protein N-terminus; Cytokinesis in yeasts involves a family of proteins whose essential function is to bind Cdc14-family phosphatase and prevent this from being sequestered and inhibited in the nucleolus. This is the highly conserved N-terminus of a family of proteins which act as cytokinesis checkpoint controls by allowing cells to cope with cytokinesis defects. These proteins are required for rDNA silencing and mini-chromosome maintenance.


:

Pssm-ID: 431263  Cd Length: 71  Bit Score: 101.46  E-value: 5.73e-26
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 398364905   83 KKFLHFTDGDNTLLQLSNEILTKFDRLYPNfKESIEIVSLQDRHGCDLDSEFIIKDVFENDGVVLVILKDE 153
Cdd:pfam10407   2 KKFLHLTDPSNTLLELSDEIVERFKKLYPD-EDELEILSLQDENGCDLDPDFLVKDVFNSNNLVRVILDNE 71
 
Name Accession Description Interval E-value
Cytokin_check_N pfam10407
Cdc14 phosphatase binding protein N-terminus; Cytokinesis in yeasts involves a family of ...
 83-153 5.73e-26

Cdc14 phosphatase binding protein N-terminus; Cytokinesis in yeasts involves a family of proteins whose essential function is to bind Cdc14-family phosphatase and prevent this from being sequestered and inhibited in the nucleolus. This is the highly conserved N-terminus of a family of proteins which act as cytokinesis checkpoint controls by allowing cells to cope with cytokinesis defects. These proteins are required for rDNA silencing and mini-chromosome maintenance.


Pssm-ID: 431263  Cd Length: 71  Bit Score: 101.46  E-value: 5.73e-26
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 398364905   83 KKFLHFTDGDNTLLQLSNEILTKFDRLYPNfKESIEIVSLQDRHGCDLDSEFIIKDVFENDGVVLVILKDE 153
Cdd:pfam10407   2 KKFLHLTDPSNTLLELSDEIVERFKKLYPD-EDELEILSLQDENGCDLDPDFLVKDVFNSNNLVRVILDNE 71
 
Name Accession Description Interval E-value
Cytokin_check_N pfam10407
Cdc14 phosphatase binding protein N-terminus; Cytokinesis in yeasts involves a family of ...
 83-153 5.73e-26

Cdc14 phosphatase binding protein N-terminus; Cytokinesis in yeasts involves a family of proteins whose essential function is to bind Cdc14-family phosphatase and prevent this from being sequestered and inhibited in the nucleolus. This is the highly conserved N-terminus of a family of proteins which act as cytokinesis checkpoint controls by allowing cells to cope with cytokinesis defects. These proteins are required for rDNA silencing and mini-chromosome maintenance.


Pssm-ID: 431263  Cd Length: 71  Bit Score: 101.46  E-value: 5.73e-26
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 398364905   83 KKFLHFTDGDNTLLQLSNEILTKFDRLYPNfKESIEIVSLQDRHGCDLDSEFIIKDVFENDGVVLVILKDE 153
Cdd:pfam10407   2 KKFLHLTDPSNTLLELSDEIVERFKKLYPD-EDELEILSLQDENGCDLDPDFLVKDVFNSNNLVRVILDNE 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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