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Conserved domains on  [gi|6323041|ref|NP_013113|]
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Gat3p [Saccharomyces cerevisiae S288C]

Protein Classification

GATA-type transcription factor( domain architecture ID 1009222)

GATA-type transcription factor binds to the DNA consensus sequence [AT]GATA[AG] and may function as a transcription factor/regulator

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GAT1 super family cl35034
GATA Zn-finger-containing transcription factor [Transcription];
1-141 2.20e-41

GATA Zn-finger-containing transcription factor [Transcription];


The actual alignment was detected with superfamily member COG5641:

Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 143.47  E-value: 2.20e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323041    1 MNIKTLCHPEYKRISVESLLNPVEETIDCEKPHSQTKINTaKPISASLYVTTNNTAVVQHNVQKRKGV---TRRCPQCAV 77
Cdd:COG5641 162 SNCKTTSTPLWRRASSESSLPGNNLCNACGLYLKLHGSPR-APISLKSDSIKSRSSRSSHNNNDSNGEnanTESIGNSSA 240

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6323041   78 IKTSPQWREGPDGEVTLCNACGLFYRKIFLVFGKDLAKRYFNEIKGVSVKRKVPKSLYGVTRTR 141
Cdd:COG5641 241 SKLTKSWEERPQGRQLLSDAGSLSPRSNNPKSPLLEGLMGSTSLQPVSTPKLVLPSDKKRSTLT 304
 
Name Accession Description Interval E-value
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
1-141 2.20e-41

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 143.47  E-value: 2.20e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323041    1 MNIKTLCHPEYKRISVESLLNPVEETIDCEKPHSQTKINTaKPISASLYVTTNNTAVVQHNVQKRKGV---TRRCPQCAV 77
Cdd:COG5641 162 SNCKTTSTPLWRRASSESSLPGNNLCNACGLYLKLHGSPR-APISLKSDSIKSRSSRSSHNNNDSNGEnanTESIGNSSA 240

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6323041   78 IKTSPQWREGPDGEVTLCNACGLFYRKIFLVFGKDLAKRYFNEIKGVSVKRKVPKSLYGVTRTR 141
Cdd:COG5641 241 SKLTKSWEERPQGRQLLSDAGSLSPRSNNPKSPLLEGLMGSTSLQPVSTPKLVLPSDKKRSTLT 304
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 71-127 6.48e-14

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 61.62  E-value: 6.48e-14
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 6323041   71 RCPQCAVIKTsPQWREGPDGEVTLCNACGLFYRKIFlvFGKDLAKRYFNEIKGVSVK 127
Cdd:cd00202   1 ACSNCGTTTT-PLWRRGPSGGSTLCNACGLYWKKHG--VMRPLSKRKKDQIKRRNRK 54
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
67-104 7.94e-14

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 61.67  E-value: 7.94e-14
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 6323041      67 GVTRRCPQCAViKTSPQWREGPDGEVTLCNACGLFYRK 104
Cdd:smart00401   1 GSGRSCSNCGT-TETPLWRRGPSGNKTLCNACGLYYKK 37
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 72-104 1.06e-12

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 58.10  E-value: 1.06e-12
                          10        20        30
                  ....*....|....*....|....*....|...
gi 6323041     72 CPQCAVIKTsPQWREGPDGEVTLCNACGLFYRK 104
Cdd:pfam00320   1 CSNCGTTKT-PLWRRGPNGNRTLCNACGLYYKK 32
 
Name Accession Description Interval E-value
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
1-141 2.20e-41

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 143.47  E-value: 2.20e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323041    1 MNIKTLCHPEYKRISVESLLNPVEETIDCEKPHSQTKINTaKPISASLYVTTNNTAVVQHNVQKRKGV---TRRCPQCAV 77
Cdd:COG5641 162 SNCKTTSTPLWRRASSESSLPGNNLCNACGLYLKLHGSPR-APISLKSDSIKSRSSRSSHNNNDSNGEnanTESIGNSSA 240

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6323041   78 IKTSPQWREGPDGEVTLCNACGLFYRKIFLVFGKDLAKRYFNEIKGVSVKRKVPKSLYGVTRTR 141
Cdd:COG5641 241 SKLTKSWEERPQGRQLLSDAGSLSPRSNNPKSPLLEGLMGSTSLQPVSTPKLVLPSDKKRSTLT 304
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 71-127 6.48e-14

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 61.62  E-value: 6.48e-14
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 6323041   71 RCPQCAVIKTsPQWREGPDGEVTLCNACGLFYRKIFlvFGKDLAKRYFNEIKGVSVK 127
Cdd:cd00202   1 ACSNCGTTTT-PLWRRGPSGGSTLCNACGLYWKKHG--VMRPLSKRKKDQIKRRNRK 54
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
67-104 7.94e-14

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 61.67  E-value: 7.94e-14
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 6323041      67 GVTRRCPQCAViKTSPQWREGPDGEVTLCNACGLFYRK 104
Cdd:smart00401   1 GSGRSCSNCGT-TETPLWRRGPSGNKTLCNACGLYYKK 37
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 72-104 1.06e-12

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 58.10  E-value: 1.06e-12
                          10        20        30
                  ....*....|....*....|....*....|...
gi 6323041     72 CPQCAVIKTsPQWREGPDGEVTLCNACGLFYRK 104
Cdd:pfam00320   1 CSNCGTTKT-PLWRRGPNGNRTLCNACGLYYKK 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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