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Conserved domains on  [gi|398366151|ref|NP_013513|]
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rRNA-processing protein UTP21 [Saccharomyces cerevisiae S288C]

Protein Classification

WD40 and Utp21 domain-containing protein( domain architecture ID 13235555)

WD40 and Utp21 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Utp21 pfam04192
Utp21 specific WD40 associated putative domain; Utp21 is a subunit of U3 snoRNP, which is ...
 714-937 3.91e-99

Utp21 specific WD40 associated putative domain; Utp21 is a subunit of U3 snoRNP, which is essential for synthesis of 18S rRNA.


:

Pssm-ID: 461219  Cd Length: 209  Bit Score: 309.08  E-value: 3.91e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151  714 EQIDKELLTLSIGPRSKMNTLLHLDVIRKRSKPKEAPKKSEKLPFFLQLSGEKVGDEASVREGIAHETPEEihrrdqEAQ 793
Cdd:pfam04192   1 DQLSEDLVTLSLLPRSRWQTLLHLDLIKQRNKPKEAPKKPEKAPFFLPTLGGLVGDFASVEAQEEEEEEEE------EER 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151  794 KKLdaeeqmNKFkvtGRLGFESHFTKQLREGSQSKDYSSLLATLINFSPAAVDLEIRSLNSFEPFDEIVWFIDALTQGLK 873
Cdd:pfam04192  75 SRL------LKL---GSLGFESEFTKLLREGSETGDYTPFLEYLKSLSPSAIDLEIRSLNSGGPLEELVSFIRALTSRLK 145

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 398366151  874 SNKNFELYETFMSLLFKAHGDVIHANNkNQDIASALQNWEDVHKKE-DRLDDLVKFCMGVAAFVT 937
Cdd:pfam04192 146 SNRDFELVQAYMAVFLKLHGDVIHSNE-EEELREALEEWKSVQEEEwERLDELVGYCSGVVGFLR 209
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 284-613 3.78e-44

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


:

Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 161.73  E-value: 3.78e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 284 IHVLKnIHResyGGVTQATFLNGQPIIVTSGGDNSLKeyVFDpslsqgsgdvvVQPPRYLRSRGGHSQPPSYIAFaDSQS 363
Cdd:cd00200    2 RRTLK-GHT---GGVTCVAFSPDGKLLATGSGDGTIK--VWD-----------LETGELLRTLKGHTGPVRDVAA-SADG 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 364 HFMLSASKDRSLWSFSLRKDAQSQEMSQrlHKKqdggrvggstikskfpEIVALAIENARigeweNIITAHKDEKFARTW 443
Cdd:cd00200   64 TYLASGSSDKTIRLWDLETGECVRTLTG--HTS----------------YVSSVAFSPDG-----RILSSSSRDKTIKVW 120

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 444 DMRNKRVGRwTFDTTDDgFVKSVAMSQCGNFGFIGSSNGSITIYNMQSGILRKKYKLHKRAVTGISLDGMNRKMVSCGLD 523
Cdd:cd00200  121 DVETGKCLT-TLRGHTD-WVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSD 198

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 524 GIVGFYDFNKSTLLGKLKL-DAPITAMVYHRSSDLFALALDDLSIVVIDAVTQRVVRQLWGHSNRITAFDFSPEGRWIVS 602
Cdd:cd00200  199 GTIKLWDLSTGKCLGTLRGhENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLAS 278

                        330
                 ....*....|.
gi 398366151 603 ASLDSTIRTWD 613
Cdd:cd00200  279 GSADGTIRIWD 289
WD40 super family cl29593
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 81-377 4.33e-12

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


The actual alignment was detected with superfamily member cd00200:

Pssm-ID: 475233 [Multi-domain]  Cd Length: 289  Bit Score: 67.75  E-value: 4.33e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151  81 VALSAHFHYVYAAYENKVGI---YKRGIEEHLLELETDANVEHLCI-FGDYLCASTDDNSIFIYKKSDPQdkypsefytk 156
Cdd:cd00200   15 VAFSPDGKLLATGSGDGTIKvwdLETGELLRTLKGHTGPVRDVAASaDGTYLASGSSDKTIRLWDLETGE---------- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 157 lTVTEIQG--GEIVSLqhlaTYLNKLTVVTKS----NVLLFNVRTGKLVFTSNEFPDQITTAEPAPVLDIIALGTVTGEV 230
Cdd:cd00200   85 -CVRTLTGhtSYVSSV----AFSPDGRILSSSsrdkTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 231 IMFNMRKGKRIRTIKIPQSRISSLSFRTDGSSHLSvGTSSGDLIFYDLDRRSRIHVLKnIHREsygGVTQATFLNGQPII 310
Cdd:cd00200  160 KLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLS-SSSDGTIKLWDLSTGKCLGTLR-GHEN---GVNSVAFSPDGYLL 234

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 398366151 311 VTSGGDNSLKeyVFDpslsqgsgdvvVQPPRYLRSRGGHSQPPSYIAFADSqSHFMLSASKDRS--LWS 377
Cdd:cd00200  235 ASGSEDGTIR--VWD-----------LRTGECVQTLSGHTNSVTSLAWSPD-GKRLASGSADGTirIWD 289
 
Name Accession Description Interval E-value
Utp21 pfam04192
Utp21 specific WD40 associated putative domain; Utp21 is a subunit of U3 snoRNP, which is ...
 714-937 3.91e-99

Utp21 specific WD40 associated putative domain; Utp21 is a subunit of U3 snoRNP, which is essential for synthesis of 18S rRNA.


Pssm-ID: 461219  Cd Length: 209  Bit Score: 309.08  E-value: 3.91e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151  714 EQIDKELLTLSIGPRSKMNTLLHLDVIRKRSKPKEAPKKSEKLPFFLQLSGEKVGDEASVREGIAHETPEEihrrdqEAQ 793
Cdd:pfam04192   1 DQLSEDLVTLSLLPRSRWQTLLHLDLIKQRNKPKEAPKKPEKAPFFLPTLGGLVGDFASVEAQEEEEEEEE------EER 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151  794 KKLdaeeqmNKFkvtGRLGFESHFTKQLREGSQSKDYSSLLATLINFSPAAVDLEIRSLNSFEPFDEIVWFIDALTQGLK 873
Cdd:pfam04192  75 SRL------LKL---GSLGFESEFTKLLREGSETGDYTPFLEYLKSLSPSAIDLEIRSLNSGGPLEELVSFIRALTSRLK 145

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 398366151  874 SNKNFELYETFMSLLFKAHGDVIHANNkNQDIASALQNWEDVHKKE-DRLDDLVKFCMGVAAFVT 937
Cdd:pfam04192 146 SNRDFELVQAYMAVFLKLHGDVIHSNE-EEELREALEEWKSVQEEEwERLDELVGYCSGVVGFLR 209
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 284-613 3.78e-44

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 161.73  E-value: 3.78e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 284 IHVLKnIHResyGGVTQATFLNGQPIIVTSGGDNSLKeyVFDpslsqgsgdvvVQPPRYLRSRGGHSQPPSYIAFaDSQS 363
Cdd:cd00200    2 RRTLK-GHT---GGVTCVAFSPDGKLLATGSGDGTIK--VWD-----------LETGELLRTLKGHTGPVRDVAA-SADG 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 364 HFMLSASKDRSLWSFSLRKDAQSQEMSQrlHKKqdggrvggstikskfpEIVALAIENARigeweNIITAHKDEKFARTW 443
Cdd:cd00200   64 TYLASGSSDKTIRLWDLETGECVRTLTG--HTS----------------YVSSVAFSPDG-----RILSSSSRDKTIKVW 120

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 444 DMRNKRVGRwTFDTTDDgFVKSVAMSQCGNFGFIGSSNGSITIYNMQSGILRKKYKLHKRAVTGISLDGMNRKMVSCGLD 523
Cdd:cd00200  121 DVETGKCLT-TLRGHTD-WVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSD 198

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 524 GIVGFYDFNKSTLLGKLKL-DAPITAMVYHRSSDLFALALDDLSIVVIDAVTQRVVRQLWGHSNRITAFDFSPEGRWIVS 602
Cdd:cd00200  199 GTIKLWDLSTGKCLGTLRGhENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLAS 278

                        330
                 ....*....|.
gi 398366151 603 ASLDSTIRTWD 613
Cdd:cd00200  279 GSADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
236-654 3.02e-34

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 136.19  E-value: 3.02e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 236 RKGKRIRTIKIPQSRISSLSFRTDGSSHLSvGTSSGDLIFYDLDRRSRIHVLKNIHresyGGVTQATFLNGQPIIVTSGG 315
Cdd:COG2319   24 ALGALLLLLLGLAAAVASLAASPDGARLAA-GAGDLTLLLLDAAAGALLATLLGHT----AAVLSVAFSPDGRLLASASA 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 316 DNSLKeyVFDpslsqgsgdvvVQPPRYLRSRGGHSQPPSYIAFADSqSHFMLSASKDRS--LWsfslrkDAQSQEMSQRL 393
Cdd:COG2319   99 DGTVR--LWD-----------LATGLLLRTLTGHTGAVRSVAFSPD-GKTLASGSADGTvrLW------DLATGKLLRTL 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 394 HKKQDGgrvggstikskfpeIVALAIenARIGEWenIITAHKDEKfARTWDMRNKRVGRwTFdTTDDGFVKSVAMSQCGN 473
Cdd:COG2319  159 TGHSGA--------------VTSVAF--SPDGKL--LASGSDDGT-VRLWDLATGKLLR-TL-TGHTGAVRSVAFSPDGK 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 474 FGFIGSSNGSITIYNMQSGILRKKYKLHKRAVTGI--SLDGmnRKMVSCGLDGIVGFYDFNKSTLLGKLK-LDAPITAMV 550
Cdd:COG2319  218 LLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVafSPDG--RLLASGSADGTVRLWDLATGELLRTLTgHSGGVNSVA 295

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 551 YHRSSDLFALALDDLSIVVIDAVTQRVVRQLWGHSNRITAFDFSPEGRWIVSASLDSTIRTWDLPTGGCIDGIIV-DNVA 629
Cdd:COG2319  296 FSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGhTGAV 375

                        410       420
                 ....*....|....*....|....*
gi 398366151 630 TNVKFSPNGDLLATTHVTGNgICIW 654
Cdd:COG2319  376 TSVAFSPDGRTLASGSADGT-VRLW 399
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 81-377 4.33e-12

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 67.75  E-value: 4.33e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151  81 VALSAHFHYVYAAYENKVGI---YKRGIEEHLLELETDANVEHLCI-FGDYLCASTDDNSIFIYKKSDPQdkypsefytk 156
Cdd:cd00200   15 VAFSPDGKLLATGSGDGTIKvwdLETGELLRTLKGHTGPVRDVAASaDGTYLASGSSDKTIRLWDLETGE---------- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 157 lTVTEIQG--GEIVSLqhlaTYLNKLTVVTKS----NVLLFNVRTGKLVFTSNEFPDQITTAEPAPVLDIIALGTVTGEV 230
Cdd:cd00200   85 -CVRTLTGhtSYVSSV----AFSPDGRILSSSsrdkTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 231 IMFNMRKGKRIRTIKIPQSRISSLSFRTDGSSHLSvGTSSGDLIFYDLDRRSRIHVLKnIHREsygGVTQATFLNGQPII 310
Cdd:cd00200  160 KLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLS-SSSDGTIKLWDLSTGKCLGTLR-GHEN---GVNSVAFSPDGYLL 234

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 398366151 311 VTSGGDNSLKeyVFDpslsqgsgdvvVQPPRYLRSRGGHSQPPSYIAFADSqSHFMLSASKDRS--LWS 377
Cdd:cd00200  235 ASGSEDGTIR--VWD-----------LRTGECVQTLSGHTNSVTSLAWSPD-GKRLASGSADGTirIWD 289
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 574-613 1.89e-08

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 50.77  E-value: 1.89e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 398366151   574 TQRVVRQLWGHSNRITAFDFSPEGRWIVSASLDSTIRTWD 613
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
576-613 1.53e-07

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 48.50  E-value: 1.53e-07
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 398366151  576 RVVRQLWGHSNRITAFDFSPEGRWIVSASLDSTIRTWD 613
Cdd:pfam00400   2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
ANAPC4_WD40 pfam12894
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ...
 216-277 1.40e-05

Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,


Pssm-ID: 403945 [Multi-domain]  Cd Length: 91  Bit Score: 44.19  E-value: 1.40e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 398366151  216 PVLDIIALGTVTGEVIMFNmRKGKRIRTIKIP--QSRISSLSFRTDGSShLSVGTSSGDLIFYD 277
Cdd:pfam12894   5 PTMDLIALATEDGELLLHR-LNWQRVWTLSPDkeDLEVTSLAWRPDGKL-LAVGYSDGTVRLLD 66
 
Name Accession Description Interval E-value
Utp21 pfam04192
Utp21 specific WD40 associated putative domain; Utp21 is a subunit of U3 snoRNP, which is ...
 714-937 3.91e-99

Utp21 specific WD40 associated putative domain; Utp21 is a subunit of U3 snoRNP, which is essential for synthesis of 18S rRNA.


Pssm-ID: 461219  Cd Length: 209  Bit Score: 309.08  E-value: 3.91e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151  714 EQIDKELLTLSIGPRSKMNTLLHLDVIRKRSKPKEAPKKSEKLPFFLQLSGEKVGDEASVREGIAHETPEEihrrdqEAQ 793
Cdd:pfam04192   1 DQLSEDLVTLSLLPRSRWQTLLHLDLIKQRNKPKEAPKKPEKAPFFLPTLGGLVGDFASVEAQEEEEEEEE------EER 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151  794 KKLdaeeqmNKFkvtGRLGFESHFTKQLREGSQSKDYSSLLATLINFSPAAVDLEIRSLNSFEPFDEIVWFIDALTQGLK 873
Cdd:pfam04192  75 SRL------LKL---GSLGFESEFTKLLREGSETGDYTPFLEYLKSLSPSAIDLEIRSLNSGGPLEELVSFIRALTSRLK 145

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 398366151  874 SNKNFELYETFMSLLFKAHGDVIHANNkNQDIASALQNWEDVHKKE-DRLDDLVKFCMGVAAFVT 937
Cdd:pfam04192 146 SNRDFELVQAYMAVFLKLHGDVIHSNE-EEELREALEEWKSVQEEEwERLDELVGYCSGVVGFLR 209
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 284-613 3.78e-44

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 161.73  E-value: 3.78e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 284 IHVLKnIHResyGGVTQATFLNGQPIIVTSGGDNSLKeyVFDpslsqgsgdvvVQPPRYLRSRGGHSQPPSYIAFaDSQS 363
Cdd:cd00200    2 RRTLK-GHT---GGVTCVAFSPDGKLLATGSGDGTIK--VWD-----------LETGELLRTLKGHTGPVRDVAA-SADG 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 364 HFMLSASKDRSLWSFSLRKDAQSQEMSQrlHKKqdggrvggstikskfpEIVALAIENARigeweNIITAHKDEKFARTW 443
Cdd:cd00200   64 TYLASGSSDKTIRLWDLETGECVRTLTG--HTS----------------YVSSVAFSPDG-----RILSSSSRDKTIKVW 120

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 444 DMRNKRVGRwTFDTTDDgFVKSVAMSQCGNFGFIGSSNGSITIYNMQSGILRKKYKLHKRAVTGISLDGMNRKMVSCGLD 523
Cdd:cd00200  121 DVETGKCLT-TLRGHTD-WVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSD 198

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 524 GIVGFYDFNKSTLLGKLKL-DAPITAMVYHRSSDLFALALDDLSIVVIDAVTQRVVRQLWGHSNRITAFDFSPEGRWIVS 602
Cdd:cd00200  199 GTIKLWDLSTGKCLGTLRGhENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLAS 278

                        330
                 ....*....|.
gi 398366151 603 ASLDSTIRTWD 613
Cdd:cd00200  279 GSADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
236-654 3.02e-34

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 136.19  E-value: 3.02e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 236 RKGKRIRTIKIPQSRISSLSFRTDGSSHLSvGTSSGDLIFYDLDRRSRIHVLKNIHresyGGVTQATFLNGQPIIVTSGG 315
Cdd:COG2319   24 ALGALLLLLLGLAAAVASLAASPDGARLAA-GAGDLTLLLLDAAAGALLATLLGHT----AAVLSVAFSPDGRLLASASA 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 316 DNSLKeyVFDpslsqgsgdvvVQPPRYLRSRGGHSQPPSYIAFADSqSHFMLSASKDRS--LWsfslrkDAQSQEMSQRL 393
Cdd:COG2319   99 DGTVR--LWD-----------LATGLLLRTLTGHTGAVRSVAFSPD-GKTLASGSADGTvrLW------DLATGKLLRTL 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 394 HKKQDGgrvggstikskfpeIVALAIenARIGEWenIITAHKDEKfARTWDMRNKRVGRwTFdTTDDGFVKSVAMSQCGN 473
Cdd:COG2319  159 TGHSGA--------------VTSVAF--SPDGKL--LASGSDDGT-VRLWDLATGKLLR-TL-TGHTGAVRSVAFSPDGK 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 474 FGFIGSSNGSITIYNMQSGILRKKYKLHKRAVTGI--SLDGmnRKMVSCGLDGIVGFYDFNKSTLLGKLK-LDAPITAMV 550
Cdd:COG2319  218 LLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVafSPDG--RLLASGSADGTVRLWDLATGELLRTLTgHSGGVNSVA 295

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 551 YHRSSDLFALALDDLSIVVIDAVTQRVVRQLWGHSNRITAFDFSPEGRWIVSASLDSTIRTWDLPTGGCIDGIIV-DNVA 629
Cdd:COG2319  296 FSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGhTGAV 375

                        410       420
                 ....*....|....*....|....*
gi 398366151 630 TNVKFSPNGDLLATTHVTGNgICIW 654
Cdd:COG2319  376 TSVAFSPDGRTLASGSADGT-VRLW 399
WD40 COG2319
WD40 repeat [General function prediction only];
188-616 9.78e-33

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 131.57  E-value: 9.78e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 188 VLLFNVRTGKLVFTSNEFPDQITTAEPAPVLDIIALGTVTGEVIMFNMRKGKRIRTIKIPQSRISSLSFRTDGSsHLSVG 267
Cdd:COG2319   18 LALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGR-LLASA 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 268 TSSGDLIFYDLDRRSRIHVLKNiHResyGGVTQATFL-NGQpIIVTSGGDNSLKeyVFDpslsqgsgdvvVQPPRYLRSR 346
Cdd:COG2319   97 SADGTVRLWDLATGLLLRTLTG-HT---GAVRSVAFSpDGK-TLASGSADGTVR--LWD-----------LATGKLLRTL 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 347 GGHSQPPSYIAF-ADSQshFMLSASKDRS--LWsfslrkDAQSQEMSQRLHKKQDGgrvggstikskfpeIVALAIenAR 423
Cdd:COG2319  159 TGHSGAVTSVAFsPDGK--LLASGSDDGTvrLW------DLATGKLLRTLTGHTGA--------------VRSVAF--SP 214

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 424 IGEWenIITAHKDeKFARTWDMRNKRVGRwTFdTTDDGFVKSVAMSQCGNFGFIGSSNGSITIYNMQSGILRKKYKLHKR 503
Cdd:COG2319  215 DGKL--LASGSAD-GTVRLWDLATGKLLR-TL-TGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSG 289

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 504 AVTGI--SLDGmnRKMVSCGLDGIVGFYDFNKSTLLGKLK-LDAPITAMVYHRSSDLFALALDDLSIVVIDAVTQRVVRQ 580
Cdd:COG2319  290 GVNSVafSPDG--KLLASGSDDGTVRLWDLATGKLLRTLTgHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRT 367

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 398366151 581 LWGHSNRITAFDFSPEGRWIVSASLDSTIRTWDLPT 616
Cdd:COG2319  368 LTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 430-654 3.19e-26

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 109.73  E-value: 3.19e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 430 IITAHKDEKfARTWDMRNKRVGRwtFDTTDDGFVKSVAMSQCGNFGFIGSSNGSITIYNMQSGILRKKYKLHKRAVTGIS 509
Cdd:cd00200   24 LATGSGDGT-IKVWDLETGELLR--TLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTGHTSYVSSVA 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 510 LDGMNRKMVSCGLDGIVGFYDFNKSTLLGKLKL-DAPITAMVYHRSSDLFALALDDLSIVVIDAVTQRVVRQLWGHSNRI 588
Cdd:cd00200  101 FSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGhTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEV 180

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 398366151 589 TAFDFSPEGRWIVSASLDSTIRTWDLPTGGCIDGIIVDNVA-TNVKFSPNGDLLATTHVTGNgICIW 654
Cdd:cd00200  181 NSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGvNSVAFSPDGYLLASGSEDGT-IRVW 246
WD40 COG2319
WD40 repeat [General function prediction only];
440-654 3.11e-23

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 103.45  E-value: 3.11e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 440 ARTWDMRNKRVGRWTFDTTDDGFVKSVAMSQCGNFGFIGSSNGSITIYNMQSGILRKKYKLHKRAVTGISLDGMNRKMVS 519
Cdd:COG2319   16 LALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLAS 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 520 CGLDGIVGFYDFNKSTLLGKLK-LDAPITAMVYHRSSDLFALALDDLSIVVIDAVTQRVVRQLWGHSNRITAFDFSPEGR 598
Cdd:COG2319   96 ASADGTVRLWDLATGLLLRTLTgHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGK 175

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 398366151 599 WIVSASLDSTIRTWDLPTGGCIDGIIV-DNVATNVKFSPNGDLLATTHvTGNGICIW 654
Cdd:COG2319  176 LLASGSDDGTVRLWDLATGKLLRTLTGhTGAVRSVAFSPDGKLLASGS-ADGTVRLW 231
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 461-643 4.54e-17

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 82.77  E-value: 4.54e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 461 GFVKSVAMSQCGNFGFIGSSNGSITIYNMQSGILRKKYKLHKRAVTGISLDGMNRKMVSCGLDGIVGFYDFNkstllgkl 540
Cdd:cd00200   10 GGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLE-------- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 541 kldapitamvyhrssdlfalalddlsivvidavTQRVVRQLWGHSNRITAFDFSPEGRWIVSASLDSTIRTWDLPTGGC- 619
Cdd:cd00200   82 ---------------------------------TGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCl 128

                        170       180
                 ....*....|....*....|....*.
gi 398366151 620 --IDGIivDNVATNVKFSPNGDLLAT 643
Cdd:cd00200  129 ttLRGH--TDWVNSVAFSPDGTFVAS 152
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 81-377 4.33e-12

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 67.75  E-value: 4.33e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151  81 VALSAHFHYVYAAYENKVGI---YKRGIEEHLLELETDANVEHLCI-FGDYLCASTDDNSIFIYKKSDPQdkypsefytk 156
Cdd:cd00200   15 VAFSPDGKLLATGSGDGTIKvwdLETGELLRTLKGHTGPVRDVAASaDGTYLASGSSDKTIRLWDLETGE---------- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 157 lTVTEIQG--GEIVSLqhlaTYLNKLTVVTKS----NVLLFNVRTGKLVFTSNEFPDQITTAEPAPVLDIIALGTVTGEV 230
Cdd:cd00200   85 -CVRTLTGhtSYVSSV----AFSPDGRILSSSsrdkTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 231 IMFNMRKGKRIRTIKIPQSRISSLSFRTDGSSHLSvGTSSGDLIFYDLDRRSRIHVLKnIHREsygGVTQATFLNGQPII 310
Cdd:cd00200  160 KLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLS-SSSDGTIKLWDLSTGKCLGTLR-GHEN---GVNSVAFSPDGYLL 234

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 398366151 311 VTSGGDNSLKeyVFDpslsqgsgdvvVQPPRYLRSRGGHSQPPSYIAFADSqSHFMLSASKDRS--LWS 377
Cdd:cd00200  235 ASGSEDGTIR--VWD-----------LRTGECVQTLSGHTNSVTSLAWSPD-GKRLASGSADGTirIWD 289
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 574-613 1.89e-08

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 50.77  E-value: 1.89e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 398366151   574 TQRVVRQLWGHSNRITAFDFSPEGRWIVSASLDSTIRTWD 613
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
576-613 1.53e-07

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 48.50  E-value: 1.53e-07
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 398366151  576 RVVRQLWGHSNRITAFDFSPEGRWIVSASLDSTIRTWD 613
Cdd:pfam00400   2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
ANAPC4_WD40 pfam12894
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ...
 216-277 1.40e-05

Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,


Pssm-ID: 403945 [Multi-domain]  Cd Length: 91  Bit Score: 44.19  E-value: 1.40e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 398366151  216 PVLDIIALGTVTGEVIMFNmRKGKRIRTIKIP--QSRISSLSFRTDGSShLSVGTSSGDLIFYD 277
Cdd:pfam12894   5 PTMDLIALATEDGELLLHR-LNWQRVWTLSPDkeDLEVTSLAWRPDGKL-LAVGYSDGTVRLLD 66
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
504-659 3.24e-05

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 46.23  E-value: 3.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 504 AVTGISLDGmNRKMVSCGLDGIVGFYDFNKSTLLGKLKLDAPITAMVYHRSSD-LFALALDDLSIVVIDAVTQRVVRQlW 582
Cdd:COG3391   71 DGADAGADG-RRLYVANSGSGRVSVIDLATGKVVATIPVGGGPRGLAVDPDGGrLYVADSGNGRVSVIDTATGKVVAT-I 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 583 GHSNRITAFDFSPEGRWIVSASLDST-----IRTWDLPTGGCIDGIIVDNVATNVKFSPNGDLLATTHVTGNGICIWTNR 657
Cdd:COG3391  149 PVGAGPHGIAVDPDGKRLYVANSGSNtvsviVSVIDTATGKVVATIPVGGGPVGVAVSPDGRRLYVANRGSNTSNGGSNT 228


                 ..
gi 398366151 658 AQ 659
Cdd:COG3391  229 VS 230
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 567-655 7.30e-03

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 38.11  E-value: 7.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366151 567 IVVIDAVTQRVvRQLWGHSNRITAFDFSPEGRWIVSASLDST---IRTWDLPTGGcidGIIVDNVATNVKFSPNGDLLAT 643
Cdd:COG0823   57 IYVVDADGGEP-RRLTFGGGYNASPSWSPDGKRLAFVSRSDGrfdIYVLDLDGGA---PRRLTDGPGSPSWSPDGRRIVF 132

                         90
                 ....*....|..
gi 398366151 644 THVTGNGICIWT 655
Cdd:COG0823  133 SSDRGGRPDLYV 144
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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