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Conserved domains on  [gi|6323798|ref|NP_013869|]
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dolichyl-diphosphooligosaccharide-protein glycotransferase [Saccharomyces cerevisiae S288C]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ribophorin_II super family cl20311
Oligosaccharyltransferase subunit Ribophorin II; This family contains eukaryotic Ribophorin II ...
 156-282 9.58e-07

Oligosaccharyltransferase subunit Ribophorin II; This family contains eukaryotic Ribophorin II (RPN2) proteins. The mammalian oligosaccharyltransferase (OST) is a protein complex that effects the cotranslational N-glycosylation of newly synthesized polypeptides, and is composed of the following proteins: ribophorins I and II (RI and RII), OST48, and Dadl, N33/IAP, OST4, STT3. The family also includes the SWP1 protein from yeast. In yeast the oligosaccharyltransferase complex is composed 7 or 8 subunits, SWP1, being one of them.


The actual alignment was detected with superfamily member pfam05817:

Pssm-ID: 461749  Cd Length: 624  Bit Score: 49.97  E-value: 9.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323798    156 QLNLNFDVDHSDSSLV----DKFGIKPEIHHIFHAEPKRVAKPIAVIFVLIIFITILSLIVTWlNSCAAAFNNIPTGVTA 231
Cdd:pfam05817 498 DVELKFPEEPEKAPSPpdpkSLYGPKPEIKHLFREPEKRPPRVVSDTFTGLVLAPLLILLVLW-LKLGVNLSNFPFSLSA 576

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 6323798    232 VYFLGFIATIVGfevIFARYYLGTSIFETLFSSLYLGAPGLLTSTKFLRSF 282
Cdd:pfam05817 577 ILFHLGLGAILL---LYVLFWLQLNMFTTLKYLALLGIFTFLAGNRLLSHL 624
 
Name Accession Description Interval E-value
Ribophorin_II pfam05817
Oligosaccharyltransferase subunit Ribophorin II; This family contains eukaryotic Ribophorin II ...
 156-282 9.58e-07

Oligosaccharyltransferase subunit Ribophorin II; This family contains eukaryotic Ribophorin II (RPN2) proteins. The mammalian oligosaccharyltransferase (OST) is a protein complex that effects the cotranslational N-glycosylation of newly synthesized polypeptides, and is composed of the following proteins: ribophorins I and II (RI and RII), OST48, and Dadl, N33/IAP, OST4, STT3. The family also includes the SWP1 protein from yeast. In yeast the oligosaccharyltransferase complex is composed 7 or 8 subunits, SWP1, being one of them.


Pssm-ID: 461749  Cd Length: 624  Bit Score: 49.97  E-value: 9.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323798    156 QLNLNFDVDHSDSSLV----DKFGIKPEIHHIFHAEPKRVAKPIAVIFVLIIFITILSLIVTWlNSCAAAFNNIPTGVTA 231
Cdd:pfam05817 498 DVELKFPEEPEKAPSPpdpkSLYGPKPEIKHLFREPEKRPPRVVSDTFTGLVLAPLLILLVLW-LKLGVNLSNFPFSLSA 576

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 6323798    232 VYFLGFIATIVGfevIFARYYLGTSIFETLFSSLYLGAPGLLTSTKFLRSF 282
Cdd:pfam05817 577 ILFHLGLGAILL---LYVLFWLQLNMFTTLKYLALLGIFTFLAGNRLLSHL 624
CstA COG1966
Carbon starvation protein CstA (peptide/pyruvate transporter) [Energy production and ...
 197-268 8.52e-03

Carbon starvation protein CstA (peptide/pyruvate transporter) [Energy production and conversion, Amino acid transport and metabolism];


Pssm-ID: 441569 [Multi-domain]  Cd Length: 534  Bit Score: 37.45  E-value: 8.52e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6323798  197 VIFVLIIFITILSLIVTWLNSCAAAFNNIPTGVTAVYFLGFIATIVGFEVifarYYLGTSIFET-------LFSSLYLG 268
Cdd:COG1966 130 VLFLIFIFLLLLLVLAVFALVVANALANSPWAAFTVALTIPIAILMGLYL----YRLPGNVLEAsiigvvlLYLAIVLG 204
 
Name Accession Description Interval E-value
Ribophorin_II pfam05817
Oligosaccharyltransferase subunit Ribophorin II; This family contains eukaryotic Ribophorin II ...
 156-282 9.58e-07

Oligosaccharyltransferase subunit Ribophorin II; This family contains eukaryotic Ribophorin II (RPN2) proteins. The mammalian oligosaccharyltransferase (OST) is a protein complex that effects the cotranslational N-glycosylation of newly synthesized polypeptides, and is composed of the following proteins: ribophorins I and II (RI and RII), OST48, and Dadl, N33/IAP, OST4, STT3. The family also includes the SWP1 protein from yeast. In yeast the oligosaccharyltransferase complex is composed 7 or 8 subunits, SWP1, being one of them.


Pssm-ID: 461749  Cd Length: 624  Bit Score: 49.97  E-value: 9.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323798    156 QLNLNFDVDHSDSSLV----DKFGIKPEIHHIFHAEPKRVAKPIAVIFVLIIFITILSLIVTWlNSCAAAFNNIPTGVTA 231
Cdd:pfam05817 498 DVELKFPEEPEKAPSPpdpkSLYGPKPEIKHLFREPEKRPPRVVSDTFTGLVLAPLLILLVLW-LKLGVNLSNFPFSLSA 576

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 6323798    232 VYFLGFIATIVGfevIFARYYLGTSIFETLFSSLYLGAPGLLTSTKFLRSF 282
Cdd:pfam05817 577 ILFHLGLGAILL---LYVLFWLQLNMFTTLKYLALLGIFTFLAGNRLLSHL 624
CstA COG1966
Carbon starvation protein CstA (peptide/pyruvate transporter) [Energy production and ...
 197-268 8.52e-03

Carbon starvation protein CstA (peptide/pyruvate transporter) [Energy production and conversion, Amino acid transport and metabolism];


Pssm-ID: 441569 [Multi-domain]  Cd Length: 534  Bit Score: 37.45  E-value: 8.52e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6323798  197 VIFVLIIFITILSLIVTWLNSCAAAFNNIPTGVTAVYFLGFIATIVGFEVifarYYLGTSIFET-------LFSSLYLG 268
Cdd:COG1966 130 VLFLIFIFLLLLLVLAVFALVVANALANSPWAAFTVALTIPIAILMGLYL----YRLPGNVLEAsiigvvlLYLAIVLG 204
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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