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Conserved domains on  [gi|6323824|ref|NP_013895|]
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Hot1p [Saccharomyces cerevisiae S288C]

Protein Classification

GCR1_C domain-containing protein( domain architecture ID 10576158)

GCR1_C domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GCR1_C pfam12550
Transcriptional activator of glycolytic enzymes; This domain family is found in eukaryotes, ...
617-694 2.37e-28

Transcriptional activator of glycolytic enzymes; This domain family is found in eukaryotes, and is approximately 80 amino acids in length. This family is activates the transcription of glycolytic enzymes.


:

Pssm-ID: 432628  Cd Length: 80  Bit Score: 108.38  E-value: 2.37e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323824    617 YRILKAPTDVKTIWEEYDTGIRGKPSIKHLEAKYGNKWRLN-KNKKTFSRRKRLYKFILNGMERG-KTAQEMIETLENKR 694
Cdd:pfam12550   1 FKMSRSPKTVEELWREYYTGLNGQPSIKSLEEKYGKKWRRDsKERKTFQRRKAIVDFIERLINEGnISREEAIEILEEIR 80
ROM1 super family cl34999
RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction ...
242-437 9.24e-03

RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms];


The actual alignment was detected with superfamily member COG5422:

Pssm-ID: 227709 [Multi-domain]  Cd Length: 1175  Bit Score: 39.49  E-value: 9.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323824   242 ISAVSSAYLQKMQNNGSGRQHTADLC--TGDSNTHSGiNQHRTTNGTIDVNTNTAQLnnQFSNALNTILPDQQHN---RN 316
Cdd:COG5422   74 SSFSSSPKLFQRRNSAGPITHSPSATssTSSLNSNDG-DQFSPASDSLSFNPSSTQS--RKDSGPGDGSPVQKRKnplLP 150
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323824   317 NVSQNINQSLPNRQLGPVINTQANQNQSQVLIHNTNTHQQVNRSP---ISFPNASTDKPFKLnPNgikRRRRNTQSNNNA 393
Cdd:COG5422  151 SSSTHGTHPPIVFTDNNGSHAGAPNARSRKEIPSLGSQSMQLPSPhfrQKFSSSDTSNGFSY-PS---IRKNSRHSSNSM 226
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 6323824   394 STNDHASAAqkpiSALSPLTNSH-NSTTSMNYTNSSIHSGVTSAS 437
Cdd:COG5422  227 PSFPHSSTA----VLLKRHSGSSgASLISSNITPSSSNSEAMSTS 267
 
Name Accession Description Interval E-value
GCR1_C pfam12550
Transcriptional activator of glycolytic enzymes; This domain family is found in eukaryotes, ...
617-694 2.37e-28

Transcriptional activator of glycolytic enzymes; This domain family is found in eukaryotes, and is approximately 80 amino acids in length. This family is activates the transcription of glycolytic enzymes.


Pssm-ID: 432628  Cd Length: 80  Bit Score: 108.38  E-value: 2.37e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323824    617 YRILKAPTDVKTIWEEYDTGIRGKPSIKHLEAKYGNKWRLN-KNKKTFSRRKRLYKFILNGMERG-KTAQEMIETLENKR 694
Cdd:pfam12550   1 FKMSRSPKTVEELWREYYTGLNGQPSIKSLEEKYGKKWRRDsKERKTFQRRKAIVDFIERLINEGnISREEAIEILEEIR 80
ROM1 COG5422
RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction ...
242-437 9.24e-03

RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms];


Pssm-ID: 227709 [Multi-domain]  Cd Length: 1175  Bit Score: 39.49  E-value: 9.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323824   242 ISAVSSAYLQKMQNNGSGRQHTADLC--TGDSNTHSGiNQHRTTNGTIDVNTNTAQLnnQFSNALNTILPDQQHN---RN 316
Cdd:COG5422   74 SSFSSSPKLFQRRNSAGPITHSPSATssTSSLNSNDG-DQFSPASDSLSFNPSSTQS--RKDSGPGDGSPVQKRKnplLP 150
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323824   317 NVSQNINQSLPNRQLGPVINTQANQNQSQVLIHNTNTHQQVNRSP---ISFPNASTDKPFKLnPNgikRRRRNTQSNNNA 393
Cdd:COG5422  151 SSSTHGTHPPIVFTDNNGSHAGAPNARSRKEIPSLGSQSMQLPSPhfrQKFSSSDTSNGFSY-PS---IRKNSRHSSNSM 226
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 6323824   394 STNDHASAAqkpiSALSPLTNSH-NSTTSMNYTNSSIHSGVTSAS 437
Cdd:COG5422  227 PSFPHSSTA----VLLKRHSGSSgASLISSNITPSSSNSEAMSTS 267
 
Name Accession Description Interval E-value
GCR1_C pfam12550
Transcriptional activator of glycolytic enzymes; This domain family is found in eukaryotes, ...
617-694 2.37e-28

Transcriptional activator of glycolytic enzymes; This domain family is found in eukaryotes, and is approximately 80 amino acids in length. This family is activates the transcription of glycolytic enzymes.


Pssm-ID: 432628  Cd Length: 80  Bit Score: 108.38  E-value: 2.37e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323824    617 YRILKAPTDVKTIWEEYDTGIRGKPSIKHLEAKYGNKWRLN-KNKKTFSRRKRLYKFILNGMERG-KTAQEMIETLENKR 694
Cdd:pfam12550   1 FKMSRSPKTVEELWREYYTGLNGQPSIKSLEEKYGKKWRRDsKERKTFQRRKAIVDFIERLINEGnISREEAIEILEEIR 80
ROM1 COG5422
RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction ...
242-437 9.24e-03

RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms];


Pssm-ID: 227709 [Multi-domain]  Cd Length: 1175  Bit Score: 39.49  E-value: 9.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323824   242 ISAVSSAYLQKMQNNGSGRQHTADLC--TGDSNTHSGiNQHRTTNGTIDVNTNTAQLnnQFSNALNTILPDQQHN---RN 316
Cdd:COG5422   74 SSFSSSPKLFQRRNSAGPITHSPSATssTSSLNSNDG-DQFSPASDSLSFNPSSTQS--RKDSGPGDGSPVQKRKnplLP 150
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323824   317 NVSQNINQSLPNRQLGPVINTQANQNQSQVLIHNTNTHQQVNRSP---ISFPNASTDKPFKLnPNgikRRRRNTQSNNNA 393
Cdd:COG5422  151 SSSTHGTHPPIVFTDNNGSHAGAPNARSRKEIPSLGSQSMQLPSPhfrQKFSSSDTSNGFSY-PS---IRKNSRHSSNSM 226
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 6323824   394 STNDHASAAqkpiSALSPLTNSH-NSTTSMNYTNSSIHSGVTSAS 437
Cdd:COG5422  227 PSFPHSSTA----VLLKRHSGSSgASLISSNITPSSSNSEAMSTS 267
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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