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Conserved domains on  [gi|6324035|ref|NP_014105|]
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Rim21p [Saccharomyces cerevisiae S288C]

Protein Classification

PalH/RIM21 family protein( domain architecture ID 10555288)

PalH/RIM21 family protein similar to Saccharomyces cerevisiae pH-response regulator protein PalH/RIM21 and protein DFG16

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PalH pfam08733
PalH/RIM21; PalH (also known as RIM21) is a transmembrane protein required for proteolytic ...
16-362 6.20e-99

PalH/RIM21; PalH (also known as RIM21) is a transmembrane protein required for proteolytic cleavage of Rim101/PacC transcription factors which are activated by C terminal proteolytic processing. Rim101/PacC family proteins play a key role in pH-dependent responses and PalH has been implicated as a pH sensor.


:

Pssm-ID: 400879  Cd Length: 335  Bit Score: 302.59  E-value: 6.20e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324035     16 SCHPMKLGSGVLIQLPLYDNSAV-YAEDITFRSFCCERVpvyvstvlrnsspYRYLDEVINDWQKFIQVSDYV----GGS 90
Cdd:pfam08733   1 SCSPYLLGSGGLILLNSWNLTLVtLLNAAYFTPNCYDGD-------------FPYLPIVLEDWTLYTTLDTYNfsdnGDS 67
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324035     91 AEYAIYAVILSITSNFVITVFLTVICCInisGRAYKRILQLLRIASLLASLNLTIFITKVLRRLEKEHNVYGVVRAHSIM 170
Cdd:pfam08733  68 FYYSIYPILFSLSASCVITWMLTLLLFL---LPSTKGSPWLLKLATLLAAISLTIFLARSTKEVAEQQYYGGYQDAIELL 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324035    171 HIFSDDMTFVVLDFLATLMFQFCQVGIVIRLFQRAQEKRIIFFIGVILTITANILWVIPPFANhTTKHRNDWQILRPFVY 250
Cdd:pfam08733 145 DLINNSLAYRVLDLISVFLLQLAQVQIIIRLFPRQKEKRIIFWVGLILIILDTILWAINLFSY-NTRPDSFLDILPAFVY 223
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324035    251 LFRIAIATSYASIVIYHIWQKKKLWFKFNQMGLLTLLTILVVLLLPGFFLADVSNLWISELGEVFNTTCYVTSTVITWEW 330
Cdd:pfam08733 224 LFRLALSTLYAALVIYYTISKRKFAFSPKQTIPLAILNLLLILLPVVFFILDISNWWVSGWGEIFRWVLYVAATVIVWEW 303
                         330       340       350
                  ....*....|....*....|....*....|..
gi 6324035    331 LDRLNVLERKEEAQSILGRPIFEEEQQDYRFA 362
Cdd:pfam08733 304 INRIEILERKEEKEGVLGRRIYEDDVLFVDPA 335
 
Name Accession Description Interval E-value
PalH pfam08733
PalH/RIM21; PalH (also known as RIM21) is a transmembrane protein required for proteolytic ...
16-362 6.20e-99

PalH/RIM21; PalH (also known as RIM21) is a transmembrane protein required for proteolytic cleavage of Rim101/PacC transcription factors which are activated by C terminal proteolytic processing. Rim101/PacC family proteins play a key role in pH-dependent responses and PalH has been implicated as a pH sensor.


Pssm-ID: 400879  Cd Length: 335  Bit Score: 302.59  E-value: 6.20e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324035     16 SCHPMKLGSGVLIQLPLYDNSAV-YAEDITFRSFCCERVpvyvstvlrnsspYRYLDEVINDWQKFIQVSDYV----GGS 90
Cdd:pfam08733   1 SCSPYLLGSGGLILLNSWNLTLVtLLNAAYFTPNCYDGD-------------FPYLPIVLEDWTLYTTLDTYNfsdnGDS 67
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324035     91 AEYAIYAVILSITSNFVITVFLTVICCInisGRAYKRILQLLRIASLLASLNLTIFITKVLRRLEKEHNVYGVVRAHSIM 170
Cdd:pfam08733  68 FYYSIYPILFSLSASCVITWMLTLLLFL---LPSTKGSPWLLKLATLLAAISLTIFLARSTKEVAEQQYYGGYQDAIELL 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324035    171 HIFSDDMTFVVLDFLATLMFQFCQVGIVIRLFQRAQEKRIIFFIGVILTITANILWVIPPFANhTTKHRNDWQILRPFVY 250
Cdd:pfam08733 145 DLINNSLAYRVLDLISVFLLQLAQVQIIIRLFPRQKEKRIIFWVGLILIILDTILWAINLFSY-NTRPDSFLDILPAFVY 223
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324035    251 LFRIAIATSYASIVIYHIWQKKKLWFKFNQMGLLTLLTILVVLLLPGFFLADVSNLWISELGEVFNTTCYVTSTVITWEW 330
Cdd:pfam08733 224 LFRLALSTLYAALVIYYTISKRKFAFSPKQTIPLAILNLLLILLPVVFFILDISNWWVSGWGEIFRWVLYVAATVIVWEW 303
                         330       340       350
                  ....*....|....*....|....*....|..
gi 6324035    331 LDRLNVLERKEEAQSILGRPIFEEEQQDYRFA 362
Cdd:pfam08733 304 INRIEILERKEEKEGVLGRRIYEDDVLFVDPA 335
 
Name Accession Description Interval E-value
PalH pfam08733
PalH/RIM21; PalH (also known as RIM21) is a transmembrane protein required for proteolytic ...
16-362 6.20e-99

PalH/RIM21; PalH (also known as RIM21) is a transmembrane protein required for proteolytic cleavage of Rim101/PacC transcription factors which are activated by C terminal proteolytic processing. Rim101/PacC family proteins play a key role in pH-dependent responses and PalH has been implicated as a pH sensor.


Pssm-ID: 400879  Cd Length: 335  Bit Score: 302.59  E-value: 6.20e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324035     16 SCHPMKLGSGVLIQLPLYDNSAV-YAEDITFRSFCCERVpvyvstvlrnsspYRYLDEVINDWQKFIQVSDYV----GGS 90
Cdd:pfam08733   1 SCSPYLLGSGGLILLNSWNLTLVtLLNAAYFTPNCYDGD-------------FPYLPIVLEDWTLYTTLDTYNfsdnGDS 67
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324035     91 AEYAIYAVILSITSNFVITVFLTVICCInisGRAYKRILQLLRIASLLASLNLTIFITKVLRRLEKEHNVYGVVRAHSIM 170
Cdd:pfam08733  68 FYYSIYPILFSLSASCVITWMLTLLLFL---LPSTKGSPWLLKLATLLAAISLTIFLARSTKEVAEQQYYGGYQDAIELL 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324035    171 HIFSDDMTFVVLDFLATLMFQFCQVGIVIRLFQRAQEKRIIFFIGVILTITANILWVIPPFANhTTKHRNDWQILRPFVY 250
Cdd:pfam08733 145 DLINNSLAYRVLDLISVFLLQLAQVQIIIRLFPRQKEKRIIFWVGLILIILDTILWAINLFSY-NTRPDSFLDILPAFVY 223
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324035    251 LFRIAIATSYASIVIYHIWQKKKLWFKFNQMGLLTLLTILVVLLLPGFFLADVSNLWISELGEVFNTTCYVTSTVITWEW 330
Cdd:pfam08733 224 LFRLALSTLYAALVIYYTISKRKFAFSPKQTIPLAILNLLLILLPVVFFILDISNWWVSGWGEIFRWVLYVAATVIVWEW 303
                         330       340       350
                  ....*....|....*....|....*....|..
gi 6324035    331 LDRLNVLERKEEAQSILGRPIFEEEQQDYRFA 362
Cdd:pfam08733 304 INRIEILERKEEKEGVLGRRIYEDDVLFVDPA 335
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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