|
Name |
Accession |
Description |
Interval |
E-value |
| nop2p |
TIGR00446 |
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base ... |
273-548 |
3.40e-151 |
|
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 188051 [Multi-domain] Cd Length: 264 Bit Score: 436.51 E-value: 3.40e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 273 IRTNTLKTRRRDLAQTLVNRGVNLQPIGSWTKVglQIFDSQVPIGATPEYLAGHYILQAASSFLPVIALDPHENERILDM 352
Cdd:TIGR00446 1 IRVNTLKINVEDLLERLENRGVVLEPTCEEYFF--EVKESPFSIGSTPEYLFGYYYPQEASSMIPPIALEPREDERVLDM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 353 AAAPGGKTTYISAMMKNTGCVFANDANKSRTKSLIANIHRLGCTNTIVCNYDAREFPKVIGGFDRILLDAPCSGTGVIGK 432
Cdd:TIGR00446 79 AAAPGGKTTQISQLMKNKGCIVANEISKSRTKALISNINRMGVLNTIVINADGRKFGAYLLKFDAILLDAPCSGEGVIRK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 433 DQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVDCnskhGGVIVYSTCSVAVEEDEAVIDYALRKRPNVKLVdtgLAIGKEA 512
Cdd:TIGR00446 159 DPSRKRNWSEEDIKYCSLLQKELIDAAIDALKP----GGVLVYSTCSLEVEENEEVIDYILRKRPDVVEE---IIKGDEF 231
|
250 260 270
....*....|....*....|....*....|....*.
gi 398365157 513 FTSYRGKkfhPSVKLARRYYPHTYNVDGFFVAKFQK 548
Cdd:TIGR00446 232 FGINIGK---GEVKGALRVFPQNYDCEGFFVAKLRK 264
|
|
| Methyltr_RsmB-F |
pfam01189 |
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ... |
338-547 |
9.10e-104 |
|
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ribosomal methyltransferase RsmB/F enzyme. There is a catalytic cysteine residue at 180 in UniProtKB:Q5SII2, with another highly conserved cysteine at residue 230. It methylates the C(5) position of cytosine 2870 (m5C2870) in 25S rRNA.
Pssm-ID: 426109 [Multi-domain] Cd Length: 199 Bit Score: 312.44 E-value: 9.10e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 338 VIALDPHENERILDMAAAPGGKTTYISAMMKNTGCVFANDANKSRTKSLIANIHRLGCTNTIVCNYDAREFPKVIGG--F 415
Cdd:pfam01189 1 AILLAPQEGETILDMCAAPGGKTTHIAELMKNQGTVVAVDINKHRLKRVAENIHRLGVTNTIILNGDGRQPDQWLGGvlF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 416 DRILLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVdcnsKHGGVIVYSTCSVAVEEDEAVIDYALRK 495
Cdd:pfam01189 81 DRILLDAPCSGTGVIRRHPDVKWLRQEADIAQLAQLQKELLSAAIDLL----KPGGVLVYSTCSVLPEENEAVIEYFLQK 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 398365157 496 RPNVKLVDT------GLAIGKEAftsyrgkkfhpsvklARRYYPHTYNVDGFFVAKFQ 547
Cdd:pfam01189 157 HPDVELVPTplfepvGLAIGEQP---------------TLRLLPHTHNGDGFFIAKLR 199
|
|
| RsmB |
COG0144 |
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and ... |
229-550 |
1.86e-88 |
|
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 439914 [Multi-domain] Cd Length: 441 Bit Score: 281.51 E-value: 1.86e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 229 DRLLKDICEYFGYTPFLAEKLFNLFSPAEAMEFFEANEIARPITIRTNTLKTRRRDLAQTLVNRGVNLQPiGSWTKVGLQ 308
Cdd:COG0144 135 ADPVERLAVRYSHPEWLVERLRAAYGPEEAEALLAALNEPPPLDLRVNTLKASREELLARLAEEGIEAEP-TPLSPDGLR 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 309 IfDSQVPIGATPEYLAGHYILQAASSFLPVIALDPHENERILDMAAAPGGKTTYISAMMKNTGCVFANDANKSRTKSLIA 388
Cdd:COG0144 214 L-EGPGPVTALPGFREGLFSVQDEASQLVALLLDPKPGERVLDLCAAPGGKTLHLAELMGNKGRVVAVDISEHRLKRLRE 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 389 NIHRLGCTNTIVCNYDAREFPKVIGG-FDRILLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVdcns 467
Cdd:COG0144 293 NLARLGLSNVEVVVADARELLEWLPGkFDRVLLDAPCSGTGTLRRHPDIKWRRTPEDIAELAALQRELLDAAARLL---- 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 468 KHGGVIVYSTCSVAVEEDEAVIDYALRKRPNVKLVDTGLAIGKEAFTSYRGkkfhpsvklaRRYYPHTYNVDGFFVAKFQ 547
Cdd:COG0144 369 KPGGRLVYSTCSLLPEENEEVVEAFLARHPDFELVPLAELLPGLALTDGGY----------LRLLPHRHGTDGFFIARLR 438
|
...
gi 398365157 548 KIG 550
Cdd:COG0144 439 KKA 441
|
|
| PRK14902 |
PRK14902 |
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB; |
244-550 |
1.35e-68 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB;
Pssm-ID: 237857 [Multi-domain] Cd Length: 444 Bit Score: 229.68 E-value: 1.35e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 244 FLAEKLFNLFSPAEAMEFFEANEIARPITIRTNTLKTRRRDLAQTLVNRGVNLQPiGSWTKVGLQIfdSQVPIGATPEYL 323
Cdd:PRK14902 152 WLVKRWIDQYGEEKAEKILESLNEPPKASIRVNTLKISVEELIEKLEEEGYEVEE-SLLSPEALVI--EKGNIAGTDLFK 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 324 AGHYILQAASSFLPVIALDPHENERILDMAAAPGGKTTYISAMMKNTGCVFANDANKSRTKsLI-ANIHRLGCTNTIVCN 402
Cdd:PRK14902 229 DGLITIQDESSMLVAPALDPKGGDTVLDACAAPGGKTTHIAELLKNTGKVVALDIHEHKLK-LIeENAKRLGLTNIETKA 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 403 YDAREFPKVIGG-FDRILLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVdcnsKHGGVIVYSTCSVA 481
Cdd:PRK14902 308 LDARKVHEKFAEkFDKILVDAPCSGLGVIRRKPDIKYNKTKEDIESLQEIQLEILESVAQYL----KKGGILVYSTCTIE 383
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 398365157 482 VEEDEAVIDYALRKRPNVKLVDTglaigkeaFTSYRGKKFHPSVKLARRYYPHTYNVDGFFVAKFQKIG 550
Cdd:PRK14902 384 KEENEEVIEAFLEEHPEFELVPL--------QHEKPDELVYEVKDGYLQILPNDYGTDGFFIAKLRKKG 444
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
348-425 |
9.58e-03 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 36.25 E-value: 9.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 348 RILDMAAAPGGkttYISAMMKNTGC-VFANDANKSRTKSLIANIHRLGCTNTIVCNYDAREFPKVIGG-FDRILLDAPCS 425
Cdd:cd02440 1 RVLDLGCGTGA---LALALASGPGArVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPEADEsFDVIISDPPLH 77
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| nop2p |
TIGR00446 |
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base ... |
273-548 |
3.40e-151 |
|
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 188051 [Multi-domain] Cd Length: 264 Bit Score: 436.51 E-value: 3.40e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 273 IRTNTLKTRRRDLAQTLVNRGVNLQPIGSWTKVglQIFDSQVPIGATPEYLAGHYILQAASSFLPVIALDPHENERILDM 352
Cdd:TIGR00446 1 IRVNTLKINVEDLLERLENRGVVLEPTCEEYFF--EVKESPFSIGSTPEYLFGYYYPQEASSMIPPIALEPREDERVLDM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 353 AAAPGGKTTYISAMMKNTGCVFANDANKSRTKSLIANIHRLGCTNTIVCNYDAREFPKVIGGFDRILLDAPCSGTGVIGK 432
Cdd:TIGR00446 79 AAAPGGKTTQISQLMKNKGCIVANEISKSRTKALISNINRMGVLNTIVINADGRKFGAYLLKFDAILLDAPCSGEGVIRK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 433 DQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVDCnskhGGVIVYSTCSVAVEEDEAVIDYALRKRPNVKLVdtgLAIGKEA 512
Cdd:TIGR00446 159 DPSRKRNWSEEDIKYCSLLQKELIDAAIDALKP----GGVLVYSTCSLEVEENEEVIDYILRKRPDVVEE---IIKGDEF 231
|
250 260 270
....*....|....*....|....*....|....*.
gi 398365157 513 FTSYRGKkfhPSVKLARRYYPHTYNVDGFFVAKFQK 548
Cdd:TIGR00446 232 FGINIGK---GEVKGALRVFPQNYDCEGFFVAKLRK 264
|
|
| Methyltr_RsmB-F |
pfam01189 |
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ... |
338-547 |
9.10e-104 |
|
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ribosomal methyltransferase RsmB/F enzyme. There is a catalytic cysteine residue at 180 in UniProtKB:Q5SII2, with another highly conserved cysteine at residue 230. It methylates the C(5) position of cytosine 2870 (m5C2870) in 25S rRNA.
Pssm-ID: 426109 [Multi-domain] Cd Length: 199 Bit Score: 312.44 E-value: 9.10e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 338 VIALDPHENERILDMAAAPGGKTTYISAMMKNTGCVFANDANKSRTKSLIANIHRLGCTNTIVCNYDAREFPKVIGG--F 415
Cdd:pfam01189 1 AILLAPQEGETILDMCAAPGGKTTHIAELMKNQGTVVAVDINKHRLKRVAENIHRLGVTNTIILNGDGRQPDQWLGGvlF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 416 DRILLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVdcnsKHGGVIVYSTCSVAVEEDEAVIDYALRK 495
Cdd:pfam01189 81 DRILLDAPCSGTGVIRRHPDVKWLRQEADIAQLAQLQKELLSAAIDLL----KPGGVLVYSTCSVLPEENEAVIEYFLQK 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 398365157 496 RPNVKLVDT------GLAIGKEAftsyrgkkfhpsvklARRYYPHTYNVDGFFVAKFQ 547
Cdd:pfam01189 157 HPDVELVPTplfepvGLAIGEQP---------------TLRLLPHTHNGDGFFIAKLR 199
|
|
| RsmB |
COG0144 |
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and ... |
229-550 |
1.86e-88 |
|
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 439914 [Multi-domain] Cd Length: 441 Bit Score: 281.51 E-value: 1.86e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 229 DRLLKDICEYFGYTPFLAEKLFNLFSPAEAMEFFEANEIARPITIRTNTLKTRRRDLAQTLVNRGVNLQPiGSWTKVGLQ 308
Cdd:COG0144 135 ADPVERLAVRYSHPEWLVERLRAAYGPEEAEALLAALNEPPPLDLRVNTLKASREELLARLAEEGIEAEP-TPLSPDGLR 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 309 IfDSQVPIGATPEYLAGHYILQAASSFLPVIALDPHENERILDMAAAPGGKTTYISAMMKNTGCVFANDANKSRTKSLIA 388
Cdd:COG0144 214 L-EGPGPVTALPGFREGLFSVQDEASQLVALLLDPKPGERVLDLCAAPGGKTLHLAELMGNKGRVVAVDISEHRLKRLRE 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 389 NIHRLGCTNTIVCNYDAREFPKVIGG-FDRILLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVdcns 467
Cdd:COG0144 293 NLARLGLSNVEVVVADARELLEWLPGkFDRVLLDAPCSGTGTLRRHPDIKWRRTPEDIAELAALQRELLDAAARLL---- 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 468 KHGGVIVYSTCSVAVEEDEAVIDYALRKRPNVKLVDTGLAIGKEAFTSYRGkkfhpsvklaRRYYPHTYNVDGFFVAKFQ 547
Cdd:COG0144 369 KPGGRLVYSTCSLLPEENEEVVEAFLARHPDFELVPLAELLPGLALTDGGY----------LRLLPHRHGTDGFFIARLR 438
|
...
gi 398365157 548 KIG 550
Cdd:COG0144 439 KKA 441
|
|
| PRK14902 |
PRK14902 |
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB; |
244-550 |
1.35e-68 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB;
Pssm-ID: 237857 [Multi-domain] Cd Length: 444 Bit Score: 229.68 E-value: 1.35e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 244 FLAEKLFNLFSPAEAMEFFEANEIARPITIRTNTLKTRRRDLAQTLVNRGVNLQPiGSWTKVGLQIfdSQVPIGATPEYL 323
Cdd:PRK14902 152 WLVKRWIDQYGEEKAEKILESLNEPPKASIRVNTLKISVEELIEKLEEEGYEVEE-SLLSPEALVI--EKGNIAGTDLFK 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 324 AGHYILQAASSFLPVIALDPHENERILDMAAAPGGKTTYISAMMKNTGCVFANDANKSRTKsLI-ANIHRLGCTNTIVCN 402
Cdd:PRK14902 229 DGLITIQDESSMLVAPALDPKGGDTVLDACAAPGGKTTHIAELLKNTGKVVALDIHEHKLK-LIeENAKRLGLTNIETKA 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 403 YDAREFPKVIGG-FDRILLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVdcnsKHGGVIVYSTCSVA 481
Cdd:PRK14902 308 LDARKVHEKFAEkFDKILVDAPCSGLGVIRRKPDIKYNKTKEDIESLQEIQLEILESVAQYL----KKGGILVYSTCTIE 383
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 398365157 482 VEEDEAVIDYALRKRPNVKLVDTglaigkeaFTSYRGKKFHPSVKLARRYYPHTYNVDGFFVAKFQKIG 550
Cdd:PRK14902 384 KEENEEVIEAFLEEHPEFELVPL--------QHEKPDELVYEVKDGYLQILPNDYGTDGFFIAKLRKKG 444
|
|
| yebU |
PRK11933 |
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed |
269-574 |
1.80e-57 |
|
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed
Pssm-ID: 183387 [Multi-domain] Cd Length: 470 Bit Score: 200.52 E-value: 1.80e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 269 RPI--TIRTNTLKTRRRDLAQTLVNRGVNLQPIgSWTKVGLQI---FDSQVPIGATPEYLAGHYILQAASSFLPVIAL-- 341
Cdd:PRK11933 31 RPLrrSIRVNTLKISVADFLQLMAPYGWTLTPI-PWCEEGFWIerdDEDALPLGNTAEHLSGLFYIQEASSMLPVAALfa 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 342 DPHENERILDMAAAPGGKTTYISAMMKNTGCVFANDANKSRTKSLIANIHRLGCTNTIVCNYDAREFpkviGG-----FD 416
Cdd:PRK11933 110 DDNAPQRVLDMAAAPGSKTTQIAALMNNQGAIVANEYSASRVKVLHANISRCGVSNVALTHFDGRVF----GAalpetFD 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 417 RILLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVdcnsKHGGVIVYSTCSVAVEEDEAVIDYALRKR 496
Cdd:PRK11933 186 AILLDAPCSGEGTVRKDPDALKNWSPESNLEIAATQRELIESAFHAL----KPGGTLVYSTCTLNREENQAVCLWLKETY 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 497 PN-VKLVDTG-LAIGKEAFTSYRGkkF-HpsvklarrYYPHTYNVDGFFVAKFQKIgpSSFDDNQASAKEK-----ETAA 568
Cdd:PRK11933 262 PDaVEFEPLGdLFPGAEKALTEEG--FlH--------VFPQIYDSEGFFVARLRKT--ASVPRLPAPKYKVgkfpfTPAK 329
|
....*.
gi 398365157 569 RKEALE 574
Cdd:PRK11933 330 DKEAQE 335
|
|
| PRK14901 |
PRK14901 |
16S rRNA methyltransferase B; Provisional |
244-548 |
9.83e-47 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 237856 [Multi-domain] Cd Length: 434 Bit Score: 170.50 E-value: 9.83e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 244 FLAEKLFNLFSPAEAMEFFEANEIARPITIRTNTLKTRRRDLAQTLVNRGVNLQPIGSWTKvGLQIFDSQVPIGATPEYL 323
Cdd:PRK14901 152 WLVKLWLEWLGLEEAEQLCKWFNQPPSLDLRINPLRTSLEEVQAALAEAGITATPIPGLPQ-GLRLTGNPGSIRQLPGYE 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 324 AGHYILQAASSFLPVIALDPHENERILDMAAAPGGKTTYISAMMKNTGCVFANDANKSRTKSLIANIHRLGCTNTIVCNY 403
Cdd:PRK14901 231 EGWWTVQDRSAQLVAPLLDPQPGEVILDACAAPGGKTTHIAELMGDQGEIWAVDRSASRLKKLQENAQRLGLKSIKILAA 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 404 DAREF----PKVIGGFDRILLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVdcnsKHGGVIVYSTCS 479
Cdd:PRK14901 311 DSRNLlelkPQWRGYFDRILLDAPCSGLGTLHRHPDARWRQTPEKIQELAPLQAELLESLAPLL----KPGGTLVYATCT 386
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 398365157 480 VAVEEDEAVIDYALRKRPNVKLVDTGLAIgkeaftsyrgkkfhpsvklarryYPHTYNVDGFFVAKFQK 548
Cdd:PRK14901 387 LHPAENEAQIEQFLARHPDWKLEPPKQKI-----------------------WPHRQDGDGFFMAVLRK 432
|
|
| rsmB |
TIGR00563 |
16S rRNA (cytosine(967)-C(5))-methyltransferase; This protein is also known as sun protein. ... |
244-548 |
4.83e-44 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase; This protein is also known as sun protein. The reading frame was originally interpreted as two reading frames, fmu and fmv. The recombinant protein from E. coli was shown to methylate only C967 of small subunit (16S) ribosomal RNA and to produce only m5C at that position. The seed alignment is built from bacterial sequences only. Eukaryotic homologs include Nop2, a protein required for processing pre-rRNA, that is likely also a rRNA methyltransferase, although the fine specificity may differ. Cutoff scores are set to avoid treating archaeal and eukaroytic homologs automatically as functionally equivalent, although they may have very similar roles. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 273141 [Multi-domain] Cd Length: 426 Bit Score: 162.73 E-value: 4.83e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 244 FLAEKLFNLFsPAEAMEFFEANEIARPITIRTNTLKTRRRDLAQTLVNRGVNLQPiGSWTKVGLQIfDSQVPIGATPEYL 323
Cdd:TIGR00563 140 WLVKRLQKAY-PGQWQSICEANNQRPPMWLRINRTKHSRDEWLALLAEAGMKGFP-HDLAPDAVRL-ETPAAVHALPGFE 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 324 AGHYILQAASSFLPVIALDPHENERILDMAAAPGGKTTYISAMMKNtGCVFANDANKSRTKSLIANIHRLGCTNTI-VCN 402
Cdd:TIGR00563 217 EGWVTVQDASAQWVATWLAPQNEETILDACAAPGGKTTHILELAPQ-AQVVALDIHEHRLKRVYENLKRLGLTIKAeTKD 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 403 YDAR--EFPKVIGGFDRILLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLlsaiDSVDCNSKHGGVIVYSTCSV 480
Cdd:TIGR00563 296 GDGRgpSQWAENEQFDRILLDAPCSATGVIRRHPDIKWLRKPRDIAELAELQSEIL----DAIWPLLKTGGTLVYATCSV 371
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 398365157 481 AVEEDEAVIDYALRKRPNVKLVDTglaiGKEAFTSYRGKKFhpsvklarryYPHTYNVDGFFVAKFQK 548
Cdd:TIGR00563 372 LPEENSEQIKAFLQEHPDFPFEKT----GTPEQVRDGGLQI----------LPHAEEGDGFFYAKLIK 425
|
|
| PRK10901 |
PRK10901 |
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB; |
255-549 |
2.39e-39 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB;
Pssm-ID: 236790 [Multi-domain] Cd Length: 427 Bit Score: 149.57 E-value: 2.39e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 255 PAEAMEFFEANEIARPITIRTNTLKTRRRDLAQTLVNRGVNLQPiGSWTKVGLQIfDSQVPIGATPEYLAGHYILQAASS 334
Cdd:PRK10901 156 PEQWQAILAANNQRPPMWLRVNRRHHSRDAYLALLAEAGIEAFP-HAVGPDAIRL-ETPVPVHQLPGFAEGWVSVQDAAA 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 335 FLPVIALDPHENERILDMAAAPGGKTTYISAMMKNTGCVfANDANKSRTKSLIANIHRLGCTNTIVCNyDAREFPKVIGG 414
Cdd:PRK10901 234 QLAATLLAPQNGERVLDACAAPGGKTAHILELAPQAQVV-ALDIDAQRLERVRENLQRLGLKATVIVG-DARDPAQWWDG 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 415 --FDRILLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLlsaiDSVDCNSKHGGVIVYSTCSVAVEEDEAVIDYA 492
Cdd:PRK10901 312 qpFDRILLDAPCSATGVIRRHPDIKWLRRPEDIAALAALQSEIL----DALWPLLKPGGTLLYATCSILPEENEQQIKAF 387
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 398365157 493 LRKRPNVKLVDTGLAigkeaftsyrgkkfhpsVKLARRYYPHTYNVDGFFVAKFQKI 549
Cdd:PRK10901 388 LARHPDAELLDTGTP-----------------QQPGRQLLPGEEDGDGFFYALLIKR 427
|
|
| PRK14904 |
PRK14904 |
16S rRNA methyltransferase B; Provisional |
256-498 |
6.27e-32 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 237858 [Multi-domain] Cd Length: 445 Bit Score: 128.64 E-value: 6.27e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 256 AEAMefFEANEIARPITIRTNTLKTRRRDLAQTLVNRGVnlqpigSWTKVGL-QIFDSQVPIGATPEYLAGHYILQAASS 334
Cdd:PRK14904 168 TEAM--LSYNNQAPLFGFRINRLKTTPEKFLAAPADASV------TFEKSGLpNFFLSKDFSLFEPFLKLGLVSVQNPTQ 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 335 FLPVIALDPHENERILDMAAAPGGKTTYISAMMKNTGCVFANDANKSRTKSLIANIHRLGCTNTIVCNYDAREFPKVIgG 414
Cdd:PRK14904 240 ALACLLLNPQPGSTVLDLCAAPGGKSTFMAELMQNRGQITAVDRYPQKLEKIRSHASALGITIIETIEGDARSFSPEE-Q 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 415 FDRILLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVdcnsKHGGVIVYSTCSVAVEEDEAVIDYALR 494
Cdd:PRK14904 319 PDAILLDAPCTGTGVLGRRAELRWKLTPEKLAELVGLQAELLDHAASLL----KPGGVLVYATCSIEPEENELQIEAFLQ 394
|
....
gi 398365157 495 KRPN 498
Cdd:PRK14904 395 RHPE 398
|
|
| PRK14903 |
PRK14903 |
16S rRNA methyltransferase B; Provisional |
253-504 |
1.29e-30 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 184896 [Multi-domain] Cd Length: 431 Bit Score: 124.60 E-value: 1.29e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 253 FSPAEA-MEFFEANEIARPITIRTNTLKTRRRDLAQTLVNRGVNLQPiGSWTKVGLQIFDSQVPIGATPEYLAGHYILQA 331
Cdd:PRK14903 145 FLPEEAvLRIMEWNQEPLPTMLRVNSLAITREEVIKILAEEGTEAVP-GKHSPFSLIVRKLGVNMNDSRVIKDGLATVQG 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 332 ASSFLPVIALDPHENERILDMAAAPGGKTTYISAMMKNTGCVFANDANKSRTKSLIANIHRLGCTNTIVCNYDAREFPKV 411
Cdd:PRK14903 224 ESSQIVPLLMELEPGLRVLDTCAAPGGKTTAIAELMKDQGKILAVDISREKIQLVEKHAKRLKLSSIEIKIADAERLTEY 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 412 IGG-FDRILLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVdcnsKHGGVIVYSTCSVAVEEDEAVID 490
Cdd:PRK14903 304 VQDtFDRILVDAPCTSLGTARNHPEVLRRVNKEDFKKLSEIQLRIVSQAWKLL----EKGGILLYSTCTVTKEENTEVVK 379
|
250
....*....|....
gi 398365157 491 YALRKRPNVKLVDT 504
Cdd:PRK14903 380 RFVYEQKDAEVIDI 393
|
|
| Methyltr_RsmF_N |
pfam17125 |
N-terminal domain of 16S rRNA methyltransferase RsmF; This is the N-terminal domain of the ... |
255-334 |
1.41e-08 |
|
N-terminal domain of 16S rRNA methyltransferase RsmF; This is the N-terminal domain of the RsmF methyl transferase. RsmF is a multi-site-specific methyltransferase that is responsible for the synthesis of three modifications on cytidines in 16S ribosomal RNA. The N-terminus is critical for stabilising the catalytic core of the enzyme.
Pssm-ID: 465356 [Multi-domain] Cd Length: 88 Bit Score: 52.09 E-value: 1.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 255 PAEAMEFFEANEIARPITIRTNTLKTRRRDLAQTLVNRgvnLQPIgSWTKVGLQIFDSQVPiGATPEYLAGHYILQAASS 334
Cdd:pfam17125 14 GDEYEAFLAAYDEPRPVGLRVNTLKISVEEFLKLSPFE---LEPV-PWCEEGFYLEERPRP-GKHPYHHAGLYYIQEPSA 88
|
|
| Trm5 |
COG2520 |
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 ... |
345-423 |
8.74e-04 |
|
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 N-methylase Trm5 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 442010 [Multi-domain] Cd Length: 333 Bit Score: 41.77 E-value: 8.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 345 ENERILDMAAAPGgkttYIS-AMMKNTGC-VFANDANKSRTKSLIANIHRLGCTNTIVC-NYDAREFPKVIGG-FDRILL 420
Cdd:COG2520 180 PGERVLDMFAGVG----PFSiPIAKRSGAkVVAIDINPDAVEYLKENIRLNKVEDRVTPiLGDAREVAPELEGkADRIIM 255
|
...
gi 398365157 421 DAP 423
Cdd:COG2520 256 NLP 258
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
348-425 |
9.58e-03 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 36.25 E-value: 9.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365157 348 RILDMAAAPGGkttYISAMMKNTGC-VFANDANKSRTKSLIANIHRLGCTNTIVCNYDAREFPKVIGG-FDRILLDAPCS 425
Cdd:cd02440 1 RVLDLGCGTGA---LALALASGPGArVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPEADEsFDVIISDPPLH 77
|
|
| |
