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Conserved domains on  [gi|6324336|ref|NP_014406|]
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Nrm1p [Saccharomyces cerevisiae S288C]

Protein Classification

Whi5 domain-containing protein( domain architecture ID 10553853)

Whi5 domain-containing protein similar to Saccharomyces cerevisiae G1-specific transcriptional repressor WHI5 and transcription factor NRM1

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Whi5 pfam08528
Whi5 like; In metazoans, cyclin-dependent kinase(CDK) dependent phosphorylation of the ...
103-127 8.20e-08

Whi5 like; In metazoans, cyclin-dependent kinase(CDK) dependent phosphorylation of the retinoblastoma Tudor suppressor protein (Rb) alleviates repression of E2F and thereby activates G1/S transcription. The cell size regulator Whi5 appears to be an analogous target of CDK activity during G1 phase.


:

Pssm-ID: 462511 [Multi-domain]  Cd Length: 25  Bit Score: 46.96  E-value: 8.20e-08
                          10        20
                  ....*....|....*....|....*
gi 6324336    103 KLQIRLQFAYYKYKTKQTDKNFTDL 127
Cdd:pfam08528   1 KLKTRLQLAMYKVQTGWEDLSLDEL 25
 
Name Accession Description Interval E-value
Whi5 pfam08528
Whi5 like; In metazoans, cyclin-dependent kinase(CDK) dependent phosphorylation of the ...
103-127 8.20e-08

Whi5 like; In metazoans, cyclin-dependent kinase(CDK) dependent phosphorylation of the retinoblastoma Tudor suppressor protein (Rb) alleviates repression of E2F and thereby activates G1/S transcription. The cell size regulator Whi5 appears to be an analogous target of CDK activity during G1 phase.


Pssm-ID: 462511 [Multi-domain]  Cd Length: 25  Bit Score: 46.96  E-value: 8.20e-08
                          10        20
                  ....*....|....*....|....*
gi 6324336    103 KLQIRLQFAYYKYKTKQTDKNFTDL 127
Cdd:pfam08528   1 KLKTRLQLAMYKVQTGWEDLSLDEL 25
 
Name Accession Description Interval E-value
Whi5 pfam08528
Whi5 like; In metazoans, cyclin-dependent kinase(CDK) dependent phosphorylation of the ...
103-127 8.20e-08

Whi5 like; In metazoans, cyclin-dependent kinase(CDK) dependent phosphorylation of the retinoblastoma Tudor suppressor protein (Rb) alleviates repression of E2F and thereby activates G1/S transcription. The cell size regulator Whi5 appears to be an analogous target of CDK activity during G1 phase.


Pssm-ID: 462511 [Multi-domain]  Cd Length: 25  Bit Score: 46.96  E-value: 8.20e-08
                          10        20
                  ....*....|....*....|....*
gi 6324336    103 KLQIRLQFAYYKYKTKQTDKNFTDL 127
Cdd:pfam08528   1 KLKTRLQLAMYKVQTGWEDLSLDEL 25
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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