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Conserved domains on  [gi|6324859|ref|NP_014928|]
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thiosulfate sulfurtransferase RDL1 [Saccharomyces cerevisiae S288C]

Protein Classification

rhodanese-like domain-containing protein( domain architecture ID 10107410)

rhodanese-like domain-containing protein similar to Mus musculus thiosulfate sulfurtransferase (rhodanese)-like domain containing 3, Saccharomyces cerevisiae mitochondrial thiosulfate sulfurtransferase, and Drosophila melanogaster heat shock protein 67B2

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RHOD_HSP67B2 cd01519
Member of the Rhodanese Homology Domain superfamily. This CD includes the heat shock protein ...
 25-131 7.97e-56

Member of the Rhodanese Homology Domain superfamily. This CD includes the heat shock protein 67B2 of Drosophila melanogaster and other similar proteins, many of which are uncharacterized.


:

Pssm-ID: 238777 [Multi-domain]  Cd Length: 106  Bit Score: 169.76  E-value: 7.97e-56
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   25 YSFEDMKRIVgKHDPNVVLVDVREPSEYSIVHIPASINVPYRSHPDAFALDPLEFEKQIGIPKPDSAKELIFYCASGKRG 104
Cdd:cd01519   1 YSFEEVKNLP-NPHPNKVLIDVREPEELKTGKIPGAINIPLSSLPDALALSEEEFEKKYGFPKPSKDKELIFYCKAGVRS 79

                        90       100
                ....*....|....*....|....*..
gi 6324859  105 GEAQKVASSHGYSNTSLYPGSMNDWVS 131
Cdd:cd01519  80 KAAAELARSLGYENVGNYPGSWLDWAA 106
 
Name Accession Description Interval E-value
RHOD_HSP67B2 cd01519
Member of the Rhodanese Homology Domain superfamily. This CD includes the heat shock protein ...
 25-131 7.97e-56

Member of the Rhodanese Homology Domain superfamily. This CD includes the heat shock protein 67B2 of Drosophila melanogaster and other similar proteins, many of which are uncharacterized.


Pssm-ID: 238777 [Multi-domain]  Cd Length: 106  Bit Score: 169.76  E-value: 7.97e-56
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   25 YSFEDMKRIVgKHDPNVVLVDVREPSEYSIVHIPASINVPYRSHPDAFALDPLEFEKQIGIPKPDSAKELIFYCASGKRG 104
Cdd:cd01519   1 YSFEEVKNLP-NPHPNKVLIDVREPEELKTGKIPGAINIPLSSLPDALALSEEEFEKKYGFPKPSKDKELIFYCKAGVRS 79

                        90       100
                ....*....|....*....|....*..
gi 6324859  105 GEAQKVASSHGYSNTSLYPGSMNDWVS 131
Cdd:cd01519  80 KAAAELARSLGYENVGNYPGSWLDWAA 106
RHOD smart00450
Rhodanese Homology Domain; An alpha beta fold found duplicated in the Rhodanese protein. The ...
 37-135 6.40e-26

Rhodanese Homology Domain; An alpha beta fold found duplicated in the Rhodanese protein. The the Cysteine containing enzymatically active version of the domain is also found in the CDC25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and stress proteins such as Senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions with a loss of the cysteine are also seen in Dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases. These are likely to play a role in protein interactions.


Pssm-ID: 197731 [Multi-domain]  Cd Length: 100  Bit Score: 93.68  E-value: 6.40e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859      37 HDPNVVLVDVREPSEYSIVHIPASINVPYRSHPD-AFALDPLEFEKQIGIPKPDSAKELIFYCASGKRGGEAQKVASSHG 115
Cdd:smart00450   1 NDEKVVLLDVRSPEEYEGGHIPGAVNIPLSELLDrRGELDILEFEELLKRLGLDKDKPVVVYCRSGNRSAKAAWLLRELG 80

                           90       100
                   ....*....|....*....|
gi 6324859     116 YSNTSLYPGSMNDWVSHGGD 135
Cdd:smart00450  81 FKNVYLLDGGYKEWSAAGPP 100
PspE COG0607
Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; ...
 38-133 4.55e-22

Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Rhodanese-related sulfurtransferase is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440372 [Multi-domain]  Cd Length: 106  Bit Score: 84.25  E-value: 4.55e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   38 DPNVVLVDVREPSEYSIVHIPASINVPYRshpdafaldplEFEKQIG-IPKpdsAKELIFYCASGKRGGEAQKVASSHGY 116
Cdd:COG0607  17 SEDAVLLDVREPEEFAAGHIPGAINIPLG-----------ELAERLDeLPK---DKPIVVYCASGGRSAQAAALLRRAGY 82

                        90
                ....*....|....*..
gi 6324859  117 SNTSLYPGSMNDWVSHG 133
Cdd:COG0607  83 TNVYNLAGGIEAWKAAG 99
Rhodanese pfam00581
Rhodanese-like domain; Rhodanese has an internal duplication. This Pfam represents a single ...
 37-130 7.07e-21

Rhodanese-like domain; Rhodanese has an internal duplication. This Pfam represents a single copy of this duplicated domain. The domain is found as a single copy in other proteins, including phosphatases and ubiquitin C-terminal hydrolases.


Pssm-ID: 425764 [Multi-domain]  Cd Length: 92  Bit Score: 80.61  E-value: 7.07e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859     37 HDPNVVLVDVREPSEYSIVHIPASINVPYRSHPDAFALDPLEFEKQIGIPKpdsAKELIFYCASGKRGGEAQKVASSHGY 116
Cdd:pfam00581   2 EDGKVVLIDVRPPEEYAKGHIPGAVNVPLSSLSLPPLPLLELLEKLLELLK---DKPIVVYCNSGNRAAAAAALLKALGY 78

                          90
                  ....*....|....
gi 6324859    117 SNTSLYPGSMNDWV 130
Cdd:pfam00581  79 KNVYVLDGGFEAWK 92
PRK05597 PRK05597
molybdopterin biosynthesis protein MoeB; Validated
 39-132 1.01e-11

molybdopterin biosynthesis protein MoeB; Validated


Pssm-ID: 235526 [Multi-domain]  Cd Length: 355  Bit Score: 60.66  E-value: 1.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859    39 PNVVLVDVREPSEYSIVHIPASINVPyrshpdafaLDplEFEKQIGIPKPDSAKELIFYCASGKRGGEAQKVASSHGYSN 118
Cdd:PRK05597 273 DGVTLIDVREPSEFAAYSIPGAHNVP---------LS--AIREGANPPSVSAGDEVVVYCAAGVRSAQAVAILERAGYTG 341

                         90
                 ....*....|....
gi 6324859   119 TSLYPGSMNDWVSH 132
Cdd:PRK05597 342 MSSLDGGIEGWLDS 355
 
Name Accession Description Interval E-value
RHOD_HSP67B2 cd01519
Member of the Rhodanese Homology Domain superfamily. This CD includes the heat shock protein ...
 25-131 7.97e-56

Member of the Rhodanese Homology Domain superfamily. This CD includes the heat shock protein 67B2 of Drosophila melanogaster and other similar proteins, many of which are uncharacterized.


Pssm-ID: 238777 [Multi-domain]  Cd Length: 106  Bit Score: 169.76  E-value: 7.97e-56
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   25 YSFEDMKRIVgKHDPNVVLVDVREPSEYSIVHIPASINVPYRSHPDAFALDPLEFEKQIGIPKPDSAKELIFYCASGKRG 104
Cdd:cd01519   1 YSFEEVKNLP-NPHPNKVLIDVREPEELKTGKIPGAINIPLSSLPDALALSEEEFEKKYGFPKPSKDKELIFYCKAGVRS 79

                        90       100
                ....*....|....*....|....*..
gi 6324859  105 GEAQKVASSHGYSNTSLYPGSMNDWVS 131
Cdd:cd01519  80 KAAAELARSLGYENVGNYPGSWLDWAA 106
RHOD smart00450
Rhodanese Homology Domain; An alpha beta fold found duplicated in the Rhodanese protein. The ...
 37-135 6.40e-26

Rhodanese Homology Domain; An alpha beta fold found duplicated in the Rhodanese protein. The the Cysteine containing enzymatically active version of the domain is also found in the CDC25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and stress proteins such as Senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions with a loss of the cysteine are also seen in Dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases. These are likely to play a role in protein interactions.


Pssm-ID: 197731 [Multi-domain]  Cd Length: 100  Bit Score: 93.68  E-value: 6.40e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859      37 HDPNVVLVDVREPSEYSIVHIPASINVPYRSHPD-AFALDPLEFEKQIGIPKPDSAKELIFYCASGKRGGEAQKVASSHG 115
Cdd:smart00450   1 NDEKVVLLDVRSPEEYEGGHIPGAVNIPLSELLDrRGELDILEFEELLKRLGLDKDKPVVVYCRSGNRSAKAAWLLRELG 80

                           90       100
                   ....*....|....*....|
gi 6324859     116 YSNTSLYPGSMNDWVSHGGD 135
Cdd:smart00450  81 FKNVYLLDGGYKEWSAAGPP 100
RHOD cd00158
Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese ...
 38-130 3.82e-22

Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.


Pssm-ID: 238089 [Multi-domain]  Cd Length: 89  Bit Score: 83.89  E-value: 3.82e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   38 DPNVVLVDVREPSEYSIVHIPASINVPYRshpdafaldplEFEKQIGIPKPDSAKELIFYCASGKRGGEAQKVASSHGYS 117
Cdd:cd00158   8 DEDAVLLDVREPEEYAAGHIPGAINIPLS-----------ELEERAALLELDKDKPIVVYCRSGNRSARAAKLLRKAGGT 76

                        90
                ....*....|...
gi 6324859  118 NTSLYPGSMNDWV 130
Cdd:cd00158  77 NVYNLEGGMLAWK 89
PspE COG0607
Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; ...
 38-133 4.55e-22

Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Rhodanese-related sulfurtransferase is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440372 [Multi-domain]  Cd Length: 106  Bit Score: 84.25  E-value: 4.55e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   38 DPNVVLVDVREPSEYSIVHIPASINVPYRshpdafaldplEFEKQIG-IPKpdsAKELIFYCASGKRGGEAQKVASSHGY 116
Cdd:COG0607  17 SEDAVLLDVREPEEFAAGHIPGAINIPLG-----------ELAERLDeLPK---DKPIVVYCASGGRSAQAAALLRRAGY 82

                        90
                ....*....|....*..
gi 6324859  117 SNTSLYPGSMNDWVSHG 133
Cdd:COG0607  83 TNVYNLAGGIEAWKAAG 99
Rhodanese pfam00581
Rhodanese-like domain; Rhodanese has an internal duplication. This Pfam represents a single ...
 37-130 7.07e-21

Rhodanese-like domain; Rhodanese has an internal duplication. This Pfam represents a single copy of this duplicated domain. The domain is found as a single copy in other proteins, including phosphatases and ubiquitin C-terminal hydrolases.


Pssm-ID: 425764 [Multi-domain]  Cd Length: 92  Bit Score: 80.61  E-value: 7.07e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859     37 HDPNVVLVDVREPSEYSIVHIPASINVPYRSHPDAFALDPLEFEKQIGIPKpdsAKELIFYCASGKRGGEAQKVASSHGY 116
Cdd:pfam00581   2 EDGKVVLIDVRPPEEYAKGHIPGAVNVPLSSLSLPPLPLLELLEKLLELLK---DKPIVVYCNSGNRAAAAAALLKALGY 78

                          90
                  ....*....|....
gi 6324859    117 SNTSLYPGSMNDWV 130
Cdd:pfam00581  79 KNVYVLDGGFEAWK 92
SseA COG2897
3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains [Inorganic ion ...
 26-134 4.30e-17

3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains [Inorganic ion transport and metabolism];


Pssm-ID: 442142 [Multi-domain]  Cd Length: 262  Bit Score: 74.83  E-value: 4.30e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   26 SFEDMKRIVGkhDPNVVLVDVREPSEYS-----IV----HIPASINVPYRSH--PDAFALDPLEFEK---QIGIpkpDSA 91
Cdd:COG2897 141 DADEVLAALG--DPDAVLVDARSPERYRgevepIDpragHIPGAVNLPWTDLldEDGTFKSAEELRAlfaALGI---DPD 215

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 6324859   92 KELIFYCASGkrggeaqkVASSH--------GYSNTSLYPGSMNDWVSHGG 134
Cdd:COG2897 216 KPVITYCGSG--------VRAAHtwlalellGYPNVRLYDGSWSEWGSDPD 258
TST_Repeat_2 cd01449
Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of ...
 25-131 3.34e-16

Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue.


Pssm-ID: 238726 [Multi-domain]  Cd Length: 118  Bit Score: 69.20  E-value: 3.34e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   25 YSFEDMKRIVgkHDPNVVLVDVREPSEYSIV-----------HIPASINVPYRSH--PDAFALDPLEFEK---QIGIpkp 88
Cdd:cd01449   1 VTAEEVLANL--DSGDVQLVDARSPERFRGEvpeprpglrsgHIPGAVNIPWTSLldEDGTFKSPEELRAlfaALGI--- 75

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 6324859   89 DSAKELIFYCASGkrggeaqkVASSH--------GYSNTSLYPGSMNDWVS 131
Cdd:cd01449  76 TPDKPVIVYCGSG--------VTACVlllalellGYKNVRLYDGSWSEWGS 118
PRK05597 PRK05597
molybdopterin biosynthesis protein MoeB; Validated
 39-132 1.01e-11

molybdopterin biosynthesis protein MoeB; Validated


Pssm-ID: 235526 [Multi-domain]  Cd Length: 355  Bit Score: 60.66  E-value: 1.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859    39 PNVVLVDVREPSEYSIVHIPASINVPyrshpdafaLDplEFEKQIGIPKPDSAKELIFYCASGKRGGEAQKVASSHGYSN 118
Cdd:PRK05597 273 DGVTLIDVREPSEFAAYSIPGAHNVP---------LS--AIREGANPPSVSAGDEVVVYCAAGVRSAQAVAILERAGYTG 341

                         90
                 ....*....|....
gi 6324859   119 TSLYPGSMNDWVSH 132
Cdd:PRK05597 342 MSSLDGGIEGWLDS 355
RHOD_1 cd01522
Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative ...
 37-136 6.11e-11

Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative rhodanese-related sulfurtransferases of several uncharacterized proteins.


Pssm-ID: 238780 [Multi-domain]  Cd Length: 117  Bit Score: 55.80  E-value: 6.11e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   37 HDPNVVLVDVREPSE-YSIVHIPASINVPYRSHPDaFALDP---LEFEKQIGIPKPdsakeLIFYCASGKRGGEAQKVAS 112
Cdd:cd01522  12 ADPQAVLVDVRTEAEwKFVGGVPDAVHVAWQVYPD-MEINPnflAELEEKVGKDRP-----VLLLCRSGNRSIAAAEAAA 85

                        90       100
                ....*....|....*....|....*.
gi 6324859  113 SHGYSNtslypgSMNdwVSHG--GDK 136
Cdd:cd01522  86 QAGFTN------VYN--VLEGfeGDL 103
PRK07411 PRK07411
molybdopterin-synthase adenylyltransferase MoeB;
15-129 2.49e-10

molybdopterin-synthase adenylyltransferase MoeB;


Pssm-ID: 180967 [Multi-domain]  Cd Length: 390  Bit Score: 56.67  E-value: 2.49e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859    15 QSKNVSNIQSYSFEDMKRIVGKHDPNVVLVDVREPSEYSIVHIPASINVPYrshPDafaldpleFEKQIGIPKPDS---A 91
Cdd:PRK07411 274 EAAQKAEIPEMTVTELKALLDSGADDFVLIDVRNPNEYEIARIPGSVLVPL---PD--------IENGPGVEKVKEllnG 342

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 6324859    92 KELIFYCASGKRGGEAQKVASSHGYSNTSLyPGSMNDW 129
Cdd:PRK07411 343 HRLIAHCKMGGRSAKALGILKEAGIEGTNV-KGGITAW 379
PRK08762 PRK08762
molybdopterin-synthase adenylyltransferase MoeB;
22-133 3.76e-10

molybdopterin-synthase adenylyltransferase MoeB;


Pssm-ID: 236337 [Multi-domain]  Cd Length: 376  Bit Score: 56.17  E-value: 3.76e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859    22 IQSYSFEDMKRIVGKHdpnVVLVDVREPSEYSIVHIPASINVPyRShpdafaldplEFEKQIGIPKPDSAKELIFYCASG 101
Cdd:PRK08762   2 IREISPAEARARAAQG---AVLIDVREAHERASGQAEGALRIP-RG----------FLELRIETHLPDRDREIVLICASG 67

                         90       100       110
                 ....*....|....*....|....*....|..
gi 6324859   102 KRGGEAQKVASSHGYSNTSLYPGSMNDWVSHG 133
Cdd:PRK08762  68 TRSAHAAATLRELGYTRVASVAGGFSAWKDAG 99
Polysulfide_ST cd01447
Polysulfide-sulfurtransferase - Rhodanese Homology Domain. This domain is believed to serve as ...
 26-133 5.80e-10

Polysulfide-sulfurtransferase - Rhodanese Homology Domain. This domain is believed to serve as a polysulfide binding and transferase domain in anaerobic gram-negative bacteria, functioning in oxidative phosphorylation with polysulfide-sulfur as a terminal electron acceptor. The active site contains the same conserved cysteine that is the catalytic residue in other Rhodanese Homology Domain proteins.


Pssm-ID: 238724 [Multi-domain]  Cd Length: 103  Bit Score: 52.81  E-value: 5.80e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   26 SFEDMKRIVGkhDPNVVLVDVREPSEYSIV-HIPASINVPyRSHPDaFALDPlefEKQIGIPKPDSAKELIFYCASGKRG 104
Cdd:cd01447   2 SPEDARALLG--SPGVLLVDVRDPRELERTgMIPGAFHAP-RGMLE-FWADP---DSPYHKPAFAEDKPFVFYCASGWRS 74

                        90       100
                ....*....|....*....|....*....
gi 6324859  105 GEAQKVASSHGYSNTSLYPGSMNDWVSHG 133
Cdd:cd01447  75 ALAGKTLQDMGLKPVYNIEGGFKDWKEAG 103
RHOD_Pyr_redox cd01524
Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus ...
 40-116 7.01e-10

Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar rhodanese-like domains found C-terminal of the pyridine nucleotide-disulphide oxidoreductase (Pyr-redox) domain and the Pyr-redox dimerization domain.


Pssm-ID: 238782 [Multi-domain]  Cd Length: 90  Bit Score: 52.27  E-value: 7.01e-10
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6324859   40 NVVLVDVREPSEYSIVHIPASINVPyrshpdafaLDplEFEKQIG-IPKpdsAKELIFYCASGKRGGEAQKVASSHGY 116
Cdd:cd01524  13 GVTLIDVRTPQEFEKGHIKGAINIP---------LD--ELRDRLNeLPK---DKEIIVYCAVGLRGYIAARILTQNGF 76
RHOD_YgaP cd01527
Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, ...
 42-112 1.41e-09

Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, and similar uncharacterized putative rhodanese-related sulfurtransferases.


Pssm-ID: 238785 [Multi-domain]  Cd Length: 99  Bit Score: 51.72  E-value: 1.41e-09
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6324859   42 VLVDVREPSEYSIVHIPASINVPyrshpdafaLDPLEfekQIGIPKPDsAKELIFYCASGKR-GGEAQKVAS 112
Cdd:cd01527  18 VLVDIREPDEYLRERIPGARLVP---------LSQLE---SEGLPLVG-ANAIIFHCRSGMRtQQNAERLAA 76
PRK07878 PRK07878
molybdopterin biosynthesis-like protein MoeZ; Validated
 40-130 2.32e-09

molybdopterin biosynthesis-like protein MoeZ; Validated


Pssm-ID: 181156 [Multi-domain]  Cd Length: 392  Bit Score: 53.94  E-value: 2.32e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859    40 NVVLVDVREPSEYSIVHIPASINVPYRSHPDAFALDPLEFEKQIgipkpdsakelIFYCASGKRGGEAQKVASSHGYSNT 119
Cdd:PRK07878 303 KIALIDVREPVEWDIVHIPGAQLIPKSEILSGEALAKLPQDRTI-----------VLYCKTGVRSAEALAALKKAGFSDA 371

                         90
                 ....*....|.
gi 6324859   120 SLYPGSMNDWV 130
Cdd:PRK07878 372 VHLQGGVVAWA 382
PRK10287 PRK10287
thiosulfate:cyanide sulfurtransferase; Provisional
 44-118 2.15e-07

thiosulfate:cyanide sulfurtransferase; Provisional


Pssm-ID: 182356 [Multi-domain]  Cd Length: 104  Bit Score: 45.99  E-value: 2.15e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6324859    44 VDVREPSEYSIVHIPASINVPYRshpdafaldplEFEKQIGIPKPDSAKELIFYCASGKRGGEAQKVASSHGYSN 118
Cdd:PRK10287  24 IDVRVPEQYQQEHVQGAINIPLK-----------EVKERIATAVPDKNDTVKLYCNAGRQSGQAKEILSEMGYTH 87
RHOD_ThiF cd01526
Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ...
 26-111 2.84e-07

Member of the Rhodanese Homology Domain superfamily. This CD includes several putative molybdopterin synthase sulfurylases including the molybdenum cofactor biosynthetic protein (CnxF) of Aspergillus nidulans and the molybdenum cofactor synthesis protein 3 (MOCS3) of Homo sapiens. These rhodanese-like domains are found C-terminal of the ThiF and MoeZ_MoeB domains.


Pssm-ID: 238784 [Multi-domain]  Cd Length: 122  Bit Score: 46.15  E-value: 2.84e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   26 SFEDMKRIVgKHDPNVVLVDVREPSEYSIVHIPASINVPYRSHPDAFALDPLEFEkqigiPKPDSAKELIFY--CasgKR 103
Cdd:cd01526  11 SVKDYKNIL-QAGKKHVLLDVRPKVHFEICRLPEAINIPLSELLSKAAELKSLQE-----LPLDNDKDSPIYvvC---RR 81


                ....*...
gi 6324859  104 GGEAQKVA 111
Cdd:cd01526  82 GNDSQTAV 89
RHOD_2 cd01528
Member of the Rhodanese Homology Domain superfamily, subgroup 2. Subgroup 2 includes ...
 38-118 4.66e-07

Member of the Rhodanese Homology Domain superfamily, subgroup 2. Subgroup 2 includes uncharacterized putative rhodanese-related domains.


Pssm-ID: 238786 [Multi-domain]  Cd Length: 101  Bit Score: 45.08  E-value: 4.66e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   38 DPNVVLVDVREPSEYSIVHIPASINVPYRSHPdafaldplefEKQIGIPKPDSAKELIFYCASGKRGGEAQKVASSHGYS 117
Cdd:cd01528  15 REEPVLIDVREPEELEIAFLPGFLHLPMSEIP----------ERSKELDSDNPDKDIVVLCHHGGRSMQVAQWLLRQGFE 84


                .
gi 6324859  118 N 118
Cdd:cd01528  85 N 85
4RHOD_Repeats cd01529
Member of the Rhodanese Homology Domain superfamily. This CD includes putative ...
 35-131 6.71e-07

Member of the Rhodanese Homology Domain superfamily. This CD includes putative rhodanese-related sulfurtransferases which contain 4 copies of the Rhodanese Homology Domain. Only the second and most of the fourth repeats contain the putative catalytic Cys residue. This CD aligns the 1st , 2nd, 3rd, and 4th repeats.


Pssm-ID: 238787 [Multi-domain]  Cd Length: 96  Bit Score: 44.59  E-value: 6.71e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   35 GKHDPNVVLVDVREPSEYSIVHIPASINVPyrshpdAFALdPLEFEKQIGIPKPDSAKELIFYCASGKRGGEAQKVASSH 114
Cdd:cd01529   7 GEHEPGTALLDVRAEDEYAAGHLPGKRSIP------GAAL-VLRSQELQALEAPGRATRYVLTCDGSLLARFAAQELLAL 79

                        90
                ....*....|....*..
gi 6324859  115 GYSNTSLYPGSMNDWVS 131
Cdd:cd01529  80 GGKPVALLDGGTSAWVA 96
Acr2p cd01531
Eukaryotic arsenate resistance proteins are members of the Rhodanese Homology Domain ...
 30-134 1.41e-06

Eukaryotic arsenate resistance proteins are members of the Rhodanese Homology Domain superfamily. Included in this CD is the Saccharomyces cerevisiae arsenate reductase protein, Acr2p, and other yeast and plant homologs.


Pssm-ID: 238789 [Multi-domain]  Cd Length: 113  Bit Score: 44.33  E-value: 1.41e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   30 MKRIVGKHDPNVVLVDVREpSEYSIVHIPASINVPYRShpdaFALDPLEFEKQIGIPKPDSakeLIFYCASGK-RGGEAQ 108
Cdd:cd01531   9 LKGWIRNGRPPFQVVDVRD-EDYAGGHIKGSWHYPSTR----FKAQLNQLVQLLSGSKKDT---VVFHCALSQvRGPSAA 80

                        90       100
                ....*....|....*....|....*.
gi 6324859  109 KVASShGYSNTSLYPGSMNDWVSHGG 134
Cdd:cd01531  81 RKFLR-YLDEEDLETSKFEVYVLHGG 105
PRK09629 PRK09629
bifunctional thiosulfate sulfurtransferase/phosphatidylserine decarboxylase; Provisional
 40-132 9.29e-06

bifunctional thiosulfate sulfurtransferase/phosphatidylserine decarboxylase; Provisional


Pssm-ID: 104071 [Multi-domain]  Cd Length: 610  Bit Score: 43.95  E-value: 9.29e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859    40 NVVLVDVREPSEYS---IV-----HIPASINVPYRSHPDA-----FALDPLEFEKQIGIpKPDsaKELIFYCASGKRGGE 106
Cdd:PRK09629 162 DLAIWDARAPTEYSgekVVaakggHIPGAVNFEWTAGMDKarnlrIRQDMPEILRDLGI-TPD--KEVITHCQTHHRSGF 238

                         90       100
                 ....*....|....*....|....*.
gi 6324859   107 AQKVASSHGYSNTSLYPGSMNDWVSH 132
Cdd:PRK09629 239 TYLVAKALGYPRVKAYAGSWGEWGNH 264
RHOD_Lact_B cd01523
Member of the Rhodanese Homology Domain superfamily. This CD includes predicted proteins with ...
 28-129 2.83e-05

Member of the Rhodanese Homology Domain superfamily. This CD includes predicted proteins with rhodanese-like domains found N-terminal of the metallo-beta-lactamase domain.


Pssm-ID: 238781 [Multi-domain]  Cd Length: 100  Bit Score: 40.56  E-value: 2.83e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   28 EDMKRIVGKHDPnVVLVDVREPSEYSIVHIPASINVPYRSHPDafalDPLEFEKQIGIPKPDSaKELIFYCAsgkRGGEA 107
Cdd:cd01523   4 EDLYARLLAGQP-LFILDVRNESDYERWKIDGENNTPYFDPYF----DFLEIEEDILDQLPDD-QEVTVICA---KEGSS 74

                        90       100
                ....*....|....*....|....*
gi 6324859  108 QKVA---SSHGYSNTSLyPGSMNDW 129
Cdd:cd01523  75 QFVAellAERGYDVDYL-AGGMKAW 98
RHOD_PspE2 cd01521
Member of the Rhodanese Homology Domain superfamily. This CD includes the putative ...
 36-100 6.13e-05

Member of the Rhodanese Homology Domain superfamily. This CD includes the putative rhodanese-like protein, Psp2, of Yersinia pestis biovar Medievalis and other similar uncharacterized proteins.


Pssm-ID: 238779 [Multi-domain]  Cd Length: 110  Bit Score: 39.64  E-value: 6.13e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6324859   36 KHDPNVVLVDVREPSEYSIVHIPASINVPYRShpdafaldpLEFEKQIGIPKpdsAKELIFYCAS 100
Cdd:cd01521  21 NGKPDFVLVDVRSAEAYARGHVPGAINLPHRE---------ICENATAKLDK---EKLFVVYCDG 73
SelU COG2603
tRNA 2-selenouridine synthase SelU, contains rhodanese domain [Translation, ribosomal ...
 40-64 1.61e-04

tRNA 2-selenouridine synthase SelU, contains rhodanese domain [Translation, ribosomal structure and biogenesis]; tRNA 2-selenouridine synthase SelU, contains rhodanese domain is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442015 [Multi-domain]  Cd Length: 341  Bit Score: 40.14  E-value: 1.61e-04
                        10        20
                ....*....|....*....|....*
gi 6324859   40 NVVLVDVREPSEYSIVHIPASINVP 64
Cdd:COG2603  16 DDPLIDVRSPVEFAEGHIPGAINLP 40
PRK11784 PRK11784
tRNA 2-selenouridine synthase; Provisional
 40-64 6.71e-04

tRNA 2-selenouridine synthase; Provisional


Pssm-ID: 236982 [Multi-domain]  Cd Length: 345  Bit Score: 38.27  E-value: 6.71e-04
                         10        20
                 ....*....|....*....|....*
gi 6324859    40 NVVLVDVREPSEYSIVHIPASINVP 64
Cdd:PRK11784  15 DTPLIDVRSPIEFAEGHIPGAINLP 39
RHOD_YbbB cd01520
Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP ...
 38-64 4.86e-03

Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB.


Pssm-ID: 238778 [Multi-domain]  Cd Length: 128  Bit Score: 34.96  E-value: 4.86e-03
                        10        20
                ....*....|....*....|....*..
gi 6324859   38 DPNVVLVDVREPSEYSIVHIPASINVP 64
Cdd:cd01520  11 KADGPLIDVRSPKEFFEGHLPGAINLP 37
4RHOD_Repeat_2 cd01533
Member of the Rhodanese Homology Domain superfamily, repeat 2. This CD includes putative ...
 24-103 5.85e-03

Member of the Rhodanese Homology Domain superfamily, repeat 2. This CD includes putative rhodanese-related sulfurtransferases which contain 4 copies of the Rhodanese Homology Domain. This CD aligns the 2nd repeat which does contain the putative catalytic Cys residue.


Pssm-ID: 238791 [Multi-domain]  Cd Length: 109  Bit Score: 34.36  E-value: 5.85e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6324859   24 SYSFEDMKRIVGKHDPnVVLVDVREPSEYSIVHIPASINVPyrshpdafaldPLEFEKQIGIPKPDSAKELIFYCASGKR 103
Cdd:cd01533  11 SVSADELAALQARGAP-LVVLDGRRFDEYRKMTIPGSVSCP-----------GAELVLRVGELAPDPRTPIVVNCAGRTR 78
4RHOD_Repeat_3 cd01534
Member of the Rhodanese Homology Domain superfamily, repeat 3. This CD includes putative ...
 28-64 6.43e-03

Member of the Rhodanese Homology Domain superfamily, repeat 3. This CD includes putative rhodanese-related sulfurtransferases which contain 4 copies of the Rhodanese Homology Domain. This CD aligns the 3rd repeat which does not contain the putative catalytic Cys residue.


Pssm-ID: 238792 [Multi-domain]  Cd Length: 95  Bit Score: 33.98  E-value: 6.43e-03
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 6324859   28 EDMKRIVGKHDPNVVLVDVREPSEYSIVHIPASINVP 64
Cdd:cd01534   4 AELARWAAEGDRTVYRFDVRTPEEYEAGHLPGFRHTP 40
SseA COG2897
3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains [Inorganic ion ...
 37-68 7.49e-03

3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains [Inorganic ion transport and metabolism];


Pssm-ID: 442142 [Multi-domain]  Cd Length: 262  Bit Score: 35.15  E-value: 7.49e-03
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 6324859   37 HDPNVVLVDVRE-----PSEYSIVHIPASINVPYRSH 68
Cdd:COG2897   6 DDPDVVILDVRWdlpdgRAAYEAGHIPGAVFLDLDTD 42
RHOD_Kc cd01525
Member of the Rhodanese Homology Domain superfamily. Included in this CD are the ...
 39-67 9.57e-03

Member of the Rhodanese Homology Domain superfamily. Included in this CD are the rhodanese-like domains found C-terminal of the serine/threonine protein kinases catalytic (S_TKc) domain and the Tre-2, BUB2p, Cdc16p (TBC) domain. The putative active site Cys residue is not present in this CD.


Pssm-ID: 238783 [Multi-domain]  Cd Length: 105  Bit Score: 33.58  E-value: 9.57e-03
                        10        20
                ....*....|....*....|....*....
gi 6324859   39 PNVVLVDVREPSEYSIVHIPASINVPYRS 67
Cdd:cd01525  15 AKLAAVDIRSSPDFRRGHIEGSINIPFSS 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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