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Conserved domains on  [gi|46309573|ref|NP_035474|]
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protein sel-1 homolog 1 isoform b precursor [Mus musculus]

Protein Classification

TPR and SEL1 domain-containing protein( domain architecture ID 11434955)

protein containing domains TPR, and SEL1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
309-498 1.49e-49

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 173.96  E-value: 1.49e-49
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 309 YYQFLAEKGDVQAQVGLGQLHLHGgRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDiVPQSNETALHYFKKAA 388
Cdd:COG0790  53 AAAAAAAAGGAEAQYNLGLMYAEG-RGVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEWYEKAA 130

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 389 DMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAF 468
Cdd:COG0790 131 EQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQ 210

                       170       180       190
                ....*....|....*....|....*....|
gi 46309573 469 YNLAQMHASGTGVMRSCHTAVELFKNVCER 498
Cdd:COG0790 211 YNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
113-389 1.90e-20

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 91.14  E-value: 1.90e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 113 AIEAEEDAAKRRQMQEAEMIYQAGMKILNGSNRKSQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLTQNIQAAKEMF 192
Cdd:COG0790  47 AAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWY 126

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 193 EKLTEEGSPKGQTGLGFLYASGLGVNSSQAKALvyytfgalggnliahmilgyrywagigvlqscesalthyrlvanhva 272
Cdd:COG0790 127 EKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAA----------------------------------------------- 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 273 sdisltggsvvqrirlpdevenpgmnsgmleedliQYYQFLAEKGDVQAQVGLGQLHLHgGRGVEQNHQRAFDYFNLAAN 352
Cdd:COG0790 160 -----------------------------------EWYRKAAEQGDADAQYNLGVLYEN-GRGVPKDPAKALEWYRKAAE 203

                       250       260       270
                ....*....|....*....|....*....|....*..
gi 46309573 353 AGNSHAMAFLGKMYSEGsDIVPQSNETALHYFKKAAD 389
Cdd:COG0790 204 QGDADAQYNLGRLYLNG-EGVEKDLEKALRWLRKAAE 239
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 610-643 5.99e-07

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


:

Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 46.36  E-value: 5.99e-07
                          10        20        30
                  ....*....|....*....|....*....|....
gi 46309573   610 AQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEA 643
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAEL 34
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 575-608 1.39e-04

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


:

Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 39.46  E-value: 1.39e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 46309573    575 ARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQH 608
Cdd:smart00671   3 AQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
309-498 1.49e-49

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 173.96  E-value: 1.49e-49
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 309 YYQFLAEKGDVQAQVGLGQLHLHGgRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDiVPQSNETALHYFKKAA 388
Cdd:COG0790  53 AAAAAAAAGGAEAQYNLGLMYAEG-RGVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEWYEKAA 130

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 389 DMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAF 468
Cdd:COG0790 131 EQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQ 210

                       170       180       190
                ....*....|....*....|....*....|
gi 46309573 469 YNLAQMHASGTGVMRSCHTAVELFKNVCER 498
Cdd:COG0790 211 YNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
113-389 1.90e-20

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 91.14  E-value: 1.90e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 113 AIEAEEDAAKRRQMQEAEMIYQAGMKILNGSNRKSQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLTQNIQAAKEMF 192
Cdd:COG0790  47 AAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWY 126

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 193 EKLTEEGSPKGQTGLGFLYASGLGVNSSQAKALvyytfgalggnliahmilgyrywagigvlqscesalthyrlvanhva 272
Cdd:COG0790 127 EKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAA----------------------------------------------- 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 273 sdisltggsvvqrirlpdevenpgmnsgmleedliQYYQFLAEKGDVQAQVGLGQLHLHgGRGVEQNHQRAFDYFNLAAN 352
Cdd:COG0790 160 -----------------------------------EWYRKAAEQGDADAQYNLGVLYEN-GRGVPKDPAKALEWYRKAAE 203

                       250       260       270
                ....*....|....*....|....*....|....*..
gi 46309573 353 AGNSHAMAFLGKMYSEGsDIVPQSNETALHYFKKAAD 389
Cdd:COG0790 204 QGDADAQYNLGRLYLNG-EGVEKDLEKALRWLRKAAE 239
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 429-464 8.39e-08

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 48.71  E-value: 8.39e-08
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 46309573    429 VDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGH 464
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 393-427 4.60e-07

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 46.75  E-value: 4.60e-07
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 46309573   393 PVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQG 427
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 610-643 5.99e-07

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 46.36  E-value: 5.99e-07
                          10        20        30
                  ....*....|....*....|....*....|....
gi 46309573   610 AQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEA 643
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAEL 34
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 610-642 9.07e-07

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 45.63  E-value: 9.07e-07
                           10        20        30
                   ....*....|....*....|....*....|...
gi 46309573    610 AQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAE 642
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAE 33
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 575-608 1.39e-04

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 39.46  E-value: 1.39e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 46309573    575 ARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQH 608
Cdd:smart00671   3 AQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 575-606 7.76e-03

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 34.80  E-value: 7.76e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 46309573   575 ARIKLGDYHFYGFGTDVDYETAFIHYRLASEQ 606
Cdd:pfam08238   3 AQYRLGYLYLYGLGVPKDPEKALEWYEKAAEL 34
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
309-498 1.49e-49

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 173.96  E-value: 1.49e-49
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 309 YYQFLAEKGDVQAQVGLGQLHLHGgRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDiVPQSNETALHYFKKAA 388
Cdd:COG0790  53 AAAAAAAAGGAEAQYNLGLMYAEG-RGVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEWYEKAA 130

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 389 DMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAF 468
Cdd:COG0790 131 EQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQ 210

                       170       180       190
                ....*....|....*....|....*....|
gi 46309573 469 YNLAQMHASGTGVMRSCHTAVELFKNVCER 498
Cdd:COG0790 211 YNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
307-459 3.52e-41

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 150.85  E-value: 3.52e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 307 IQYYQFLAEKGDVQAQVGLGQLHLHgGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDiVPQSNETALHYFKK 386
Cdd:COG0790  87 LEWFEKAAEQGDAEAQYNLGLMYEE-GLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEG-VPKDPAKAAEWYRK 164

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 46309573 387 AADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLA 459
Cdd:COG0790 165 AAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKA 237
TPR COG0790
TPR repeat [General function prediction only];
308-499 1.70e-39

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 145.84  E-value: 1.70e-39
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 308 QYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDiVPQSNETALHYFKKA 387
Cdd:COG0790  15 AAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRG-VPKDYEKALEWFEKA 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 388 ADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILA 467
Cdd:COG0790  94 AEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADA 173

                       170       180       190
                ....*....|....*....|....*....|..
gi 46309573 468 FYNLAQMHASGTGVMRSCHTAVELFKNVCERG 499
Cdd:COG0790 174 QYNLGVLYENGRGVPKDPAKALEWYRKAAEQG 205
TPR COG0790
TPR repeat [General function prediction only];
343-644 6.62e-38

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 141.60  E-value: 6.62e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 343 AFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQK 422
Cdd:COG0790  13 AAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEK 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 423 AAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKnvcergrws 502
Cdd:COG0790  93 AAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYR--------- 163

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 503 erlmtaynsykdedynaavvqylllaeqgyevaqsnaafildqreativgenetyprallhwnRAASQGYTVARIKLGDY 582
Cdd:COG0790 164 ---------------------------------------------------------------KAAEQGDADAQYNLGVL 180

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 46309573 583 HFYGFGTDVDYETAFIHYRLASEQQHsAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEAS 644
Cdd:COG0790 181 YENGRGVPKDPAKALEWYRKAAEQGD-ADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQA 241
TPR COG0790
TPR repeat [General function prediction only];
115-426 3.68e-29

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 116.57  E-value: 3.68e-29
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 115 EAEEDAAKRRQMQEAEMIYQAGMKILNGSNRKSQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLTQNIQAAKEMFEK 194
Cdd:COG0790  13 AAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEK 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 195 LTEEGSPKGQTGLGFLYASGLGVNSSQAKAlvyytfgalggnliahmilgyrywagigvlqscesalthyrlvanhvasd 274
Cdd:COG0790  93 AAEQGDAEAQYNLGLMYEEGLGVPQDYAKA-------------------------------------------------- 122

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 275 isltggsvvqrirlpdevenpgmnsgmleedlIQYYQFLAEKGDVQAQVGLGQLHLHgGRGVEQNHQRAFDYFNLAANAG 354
Cdd:COG0790 123 --------------------------------LEWYEKAAEQGDADAQYNLGLLYLN-GEGVPKDPAKAAEWYRKAAEQG 169

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 46309573 355 NSHAMAFLGKMYSEGSDiVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQ 426
Cdd:COG0790 170 DADAQYNLGVLYENGRG-VPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
113-389 1.90e-20

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 91.14  E-value: 1.90e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 113 AIEAEEDAAKRRQMQEAEMIYQAGMKILNGSNRKSQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLTQNIQAAKEMF 192
Cdd:COG0790  47 AAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWY 126

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 193 EKLTEEGSPKGQTGLGFLYASGLGVNSSQAKALvyytfgalggnliahmilgyrywagigvlqscesalthyrlvanhva 272
Cdd:COG0790 127 EKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAA----------------------------------------------- 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 273 sdisltggsvvqrirlpdevenpgmnsgmleedliQYYQFLAEKGDVQAQVGLGQLHLHgGRGVEQNHQRAFDYFNLAAN 352
Cdd:COG0790 160 -----------------------------------EWYRKAAEQGDADAQYNLGVLYEN-GRGVPKDPAKALEWYRKAAE 203

                       250       260       270
                ....*....|....*....|....*....|....*..
gi 46309573 353 AGNSHAMAFLGKMYSEGsDIVPQSNETALHYFKKAAD 389
Cdd:COG0790 204 QGDADAQYNLGRLYLNG-EGVEKDLEKALRWLRKAAE 239
TPR COG0790
TPR repeat [General function prediction only];
100-270 1.85e-15

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 76.51  E-value: 1.85e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 100 YEELKRVRKPVLTAIEAEEDAAKRrqmQEAEMIYQAGMKILNGSNRKSQKREAYRYLQKAAGMNHTKALERVSYALLFGD 179
Cdd:COG0790  73 YAEGRGVPKDYEKALEWFEKAAEQ---GDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGE 149

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 180 YLTQNIQAAKEMFEKLTEEGSPKGQTGLGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMILGYRYWAGIGVLQSCES 259
Cdd:COG0790 150 GVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEK 229

                       170
                ....*....|.
gi 46309573 260 ALTHYRLVANH 270
Cdd:COG0790 230 ALRWLRKAAEQ 240
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 429-464 8.39e-08

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 48.71  E-value: 8.39e-08
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 46309573    429 VDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGH 464
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 393-427 2.69e-07

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 47.17  E-value: 2.69e-07
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 46309573    393 PVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQG 427
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 393-427 4.60e-07

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 46.75  E-value: 4.60e-07
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 46309573   393 PVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQG 427
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 610-643 5.99e-07

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 46.36  E-value: 5.99e-07
                          10        20        30
                  ....*....|....*....|....*....|....
gi 46309573   610 AQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEA 643
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAEL 34
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 610-642 9.07e-07

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 45.63  E-value: 9.07e-07
                           10        20        30
                   ....*....|....*....|....*....|...
gi 46309573    610 AQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAE 642
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAE 33
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 429-463 1.24e-05

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 42.51  E-value: 1.24e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 46309573   429 VDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGG 463
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 356-392 2.65e-05

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 41.78  E-value: 2.65e-05
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 46309573    356 SHAMAFLGKMYSEGsDIVPQSNETALHYFKKAADMGN 392
Cdd:smart00671   1 AEAQYNLGQMYEYG-LGVPKDLEKALEYYKKAAELGN 36
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 304-537 3.48e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 46.26  E-value: 3.48e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 304 EDLIQYYQFLAEKGD--VQAQVGLGQLHLHGGRgveqnHQRAFDYFN--LAANAGNSHAMAFLGKMYSEGSDIvpqsnET 379
Cdd:COG2956  59 DRAIRIHQKLLERDPdrAEALLELAQDYLKAGL-----LDRAEELLEklLELDPDDAEALRLLAEIYEQEGDW-----EK 128

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 380 ALHYFKKAADMGNPVGQSGLGMAYLYGRgvQVNYDLALKYFQKA--AEQGWVDGQLQLGSMYYNgigvKRDYKQALKYFN 457
Cdd:COG2956 129 AIEVLERLLKLGPENAHAYCELAELYLE--QGDYDEAIEALEKAlkLDPDCARALLLLAELYLE----QGDYEEAIAALE 202

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 458 --LASQGGHILAFYNLAqmhasgtgvmrschtavELFKNVCERGRWSERLMTAYNSYKDEDYNAAVVQyLLLAEQGYEVA 535
Cdd:COG2956 203 raLEQDPDYLPALPRLA-----------------ELYEKLGDPEEALELLRKALELDPSDDLLLALAD-LLERKEGLEAA 264


                ..
gi 46309573 536 QS 537
Cdd:COG2956 265 LA 266
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 356-391 8.66e-05

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 40.20  E-value: 8.66e-05
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 46309573   356 SHAMAFLGKMYSEGSDiVPQSNETALHYFKKAADMG 391
Cdd:pfam08238   1 AEAQYRLGYLYLYGLG-VPKDPEKALEWYEKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 319-355 9.88e-05

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 39.85  E-value: 9.88e-05
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 46309573    319 VQAQVGLGQLHLHGgRGVEQNHQRAFDYFNLAANAGN 355
Cdd:smart00671   1 AEAQYNLGQMYEYG-LGVPKDLEKALEYYKKAAELGN 36
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 575-608 1.39e-04

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 39.46  E-value: 1.39e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 46309573    575 ARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQH 608
Cdd:smart00671   3 AQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 319-354 3.23e-04

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 38.66  E-value: 3.23e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 46309573   319 VQAQVGLGQLHLHGgRGVEQNHQRAFDYFNLAANAG 354
Cdd:pfam08238   1 AEAQYRLGYLYLYG-LGVPKDPEKALEWYEKAAELG 35
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
318-570 3.43e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.07  E-value: 3.43e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 318 DVQAQVGLGQLHLHGGRgveqnHQRAFDYFN--LAANAGNSHAMAFLGKMYSEGSDivpqsNETALHYFKKAADM--GNP 393
Cdd:COG0457   7 DAEAYNNLGLAYRRLGR-----YEEAIEDYEkaLELDPDDAEALYNLGLAYLRLGR-----YEEALADYEQALELdpDDA 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 394 VGQSGLGMAYLYgRGvqvNYDLALKYFQKAAEQ--GWVDGQLQLGSMYYNgigvKRDYKQALKYFN--LASQGGHILAFY 469
Cdd:COG0457  77 EALNNLGLALQA-LG---RYEEALEDYDKALELdpDDAEALYNLGLALLE----LGRYDEAIEAYEraLELDPDDADALY 148

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 470 NLAQMHASgtgvMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDEDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREAT 549
Cdd:COG0457 149 NLGIALEK----LGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLL 224

                       250       260
                ....*....|....*....|.
gi 46309573 550 IVGENETYPRALLHWNRAASQ 570
Cdd:COG0457 225 LALALLLALRLAALALYQYRA 245
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 469-499 3.15e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 35.61  E-value: 3.15e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 46309573    469 YNLAQMHASGTGVMRSCHTAVELFKNVCERG 499
Cdd:smart00671   5 YNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 575-606 7.76e-03

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 34.80  E-value: 7.76e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 46309573   575 ARIKLGDYHFYGFGTDVDYETAFIHYRLASEQ 606
Cdd:pfam08238   3 AQYRLGYLYLYGLGVPKDPEKALEWYEKAAEL 34
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 412-654 8.74e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.94  E-value: 8.74e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 412 NYDLALKYFQKAAEQ--GWVDGQLQLGSMYYNgigvKRDYKQALKYFN--LASQGGHILAFYNLAQMHASgTGVMRScht 487
Cdd:COG2956  23 QPDKAIDLLEEALELdpETVEAHLALGNLYRR----RGEYDRAIRIHQklLERDPDRAEALLELAQDYLK-AGLLDR--- 94

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 488 AVELFKNVCERGRWSE----RLMTAYNSYKDEDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREAtivgenetYPRALLH 563
Cdd:COG2956  95 AEELLEKLLELDPDDAealrLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGD--------YDEAIEA 166

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46309573 564 WNRA--ASQGYTVARIKLGDYHFYGFgtdvDYETAFIHYRLASEQQH-SAQAMFNLGYMHEKgLGIKQDihlAKRFYDMA 640
Cdd:COG2956 167 LEKAlkLDPDCARALLLLAELYLEQG----DYEEAIAALERALEQDPdYLPALPRLAELYEK-LGDPEE---ALELLRKA 238

                       250
                ....*....|....
gi 46309573 641 AEASPDAQVPVFLA 654
Cdd:COG2956 239 LELDPSDDLLLALA 252
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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