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Conserved domains on  [gi|22547134|ref|NP_057575|]
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large ribosomal subunit protein mL37 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PDCD9 super family cl06259
Mitochondrial 28S ribosomal protein S30 (PDCD9); This family consists of several eukaryotic ...
 271-383 1.29e-06

Mitochondrial 28S ribosomal protein S30 (PDCD9); This family consists of several eukaryotic mitochondrial 28S ribosomal protein S30 (or programmed cell death protein 9 PDCD9) sequences. The exact function of this family is unknown although it is known to be a component of the mitochondrial ribosome and a component in cellular apoptotic signaling pathways.


The actual alignment was detected with superfamily member pfam07147:

Pssm-ID: 462101  Cd Length: 441  Bit Score: 50.48  E-value: 1.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22547134   271 YDVKNDTGFQEGYPYPYPHTLYLL-------DKANLRpHRLQPDQ----LRAKMILFAFGSALAQARLLYGNDAKVLEQP 339
Cdd:pfam07147 291 YDHAIFVGGKLGDPHCYGHLQFHLlpdrlkrDRLILR-NYEAADQlevaLRANAIASLFAWLGAQAMYQGFWTYNDVTRP 369

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 22547134   340 VVVQSVGTDGRVFHFLVFQLNTTDL----DCNEGVKNLAWVDSDQLLY 383
Cdd:pfam07147 370 FVSQAVITDGKYFSFFCYQLNTLALhvqaDGNNPRKNLCWGTESLPLY 417
 
Name Accession Description Interval E-value
PDCD9 pfam07147
Mitochondrial 28S ribosomal protein S30 (PDCD9); This family consists of several eukaryotic ...
 271-383 1.29e-06

Mitochondrial 28S ribosomal protein S30 (PDCD9); This family consists of several eukaryotic mitochondrial 28S ribosomal protein S30 (or programmed cell death protein 9 PDCD9) sequences. The exact function of this family is unknown although it is known to be a component of the mitochondrial ribosome and a component in cellular apoptotic signaling pathways.


Pssm-ID: 462101  Cd Length: 441  Bit Score: 50.48  E-value: 1.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22547134   271 YDVKNDTGFQEGYPYPYPHTLYLL-------DKANLRpHRLQPDQ----LRAKMILFAFGSALAQARLLYGNDAKVLEQP 339
Cdd:pfam07147 291 YDHAIFVGGKLGDPHCYGHLQFHLlpdrlkrDRLILR-NYEAADQlevaLRANAIASLFAWLGAQAMYQGFWTYNDVTRP 369

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 22547134   340 VVVQSVGTDGRVFHFLVFQLNTTDL----DCNEGVKNLAWVDSDQLLY 383
Cdd:pfam07147 370 FVSQAVITDGKYFSFFCYQLNTLALhvqaDGNNPRKNLCWGTESLPLY 417
 
Name Accession Description Interval E-value
PDCD9 pfam07147
Mitochondrial 28S ribosomal protein S30 (PDCD9); This family consists of several eukaryotic ...
 271-383 1.29e-06

Mitochondrial 28S ribosomal protein S30 (PDCD9); This family consists of several eukaryotic mitochondrial 28S ribosomal protein S30 (or programmed cell death protein 9 PDCD9) sequences. The exact function of this family is unknown although it is known to be a component of the mitochondrial ribosome and a component in cellular apoptotic signaling pathways.


Pssm-ID: 462101  Cd Length: 441  Bit Score: 50.48  E-value: 1.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22547134   271 YDVKNDTGFQEGYPYPYPHTLYLL-------DKANLRpHRLQPDQ----LRAKMILFAFGSALAQARLLYGNDAKVLEQP 339
Cdd:pfam07147 291 YDHAIFVGGKLGDPHCYGHLQFHLlpdrlkrDRLILR-NYEAADQlevaLRANAIASLFAWLGAQAMYQGFWTYNDVTRP 369

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 22547134   340 VVVQSVGTDGRVFHFLVFQLNTTDL----DCNEGVKNLAWVDSDQLLY 383
Cdd:pfam07147 370 FVSQAVITDGKYFSFFCYQLNTLALhvqaDGNNPRKNLCWGTESLPLY 417
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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