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Conserved domains on  [gi|78126167|ref|NP_058911|]
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excitatory amino acid transporter 2 isoform a [Rattus norvegicus]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10448728)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
46-495 1.57e-124

Sodium:dicarboxylate symporter family;


:

Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 371.47  E-value: 1.57e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167    46 LLSLTVFGVILGAVCGGLLrlaapihPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAMVYY 124
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF-------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   125 MSTTIIAAVLGVILVLAIHPGNPKLKKQLGPgkKNDEVSSLDAFLDLIRNLFPENLVQACFQQiqtvtkkvlvappseea 204
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLALIAASL--KEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   205 nttkavisllnetmneapeetkivikkglefkdgmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIM 284
Cdd:pfam00375 135 -----------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVM 179

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   285 WYSPLGIACLICgKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSA 364
Cdd:pfam00375 180 KLAPIGVFALIA-NTVGTYGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSA 257

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   365 GTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSA 444
Cdd:pfam00375 258 ATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGG 337

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 78126167   445 GLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL 495
Cdd:pfam00375 338 GLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
 
Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
46-495 1.57e-124

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 371.47  E-value: 1.57e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167    46 LLSLTVFGVILGAVCGGLLrlaapihPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAMVYY 124
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF-------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   125 MSTTIIAAVLGVILVLAIHPGNPKLKKQLGPgkKNDEVSSLDAFLDLIRNLFPENLVQACFQQiqtvtkkvlvappseea 204
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLALIAASL--KEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   205 nttkavisllnetmneapeetkivikkglefkdgmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIM 284
Cdd:pfam00375 135 -----------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVM 179

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   285 WYSPLGIACLICgKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSA 364
Cdd:pfam00375 180 KLAPIGVFALIA-NTVGTYGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSA 257

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   365 GTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSA 444
Cdd:pfam00375 258 ATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGG 337

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 78126167   445 GLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL 495
Cdd:pfam00375 338 GLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
43-492 4.47e-124

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 370.98  E-value: 4.47e-124
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  43 KNLLLSLTVFGVILGAVCGGLLrlaapiHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 121
Cdd:COG1301   2 KLSLTLQILIALVLGILLGLLL------PELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167 122 VYYMSTTIIAAVLGVILVLAIHPGNPkLKKQLGPGKKNDEVSSLDaFLDLIRNLFPENLVQAcfqqiqtvtkkvlvapps 201
Cdd:COG1301  76 LYFLVTTTIALVIGLVVANLFQPGAG-LNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------ 135

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167 202 eeanttkavisllnetmneapeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 281
Cdd:COG1301 136 ---------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVG 181

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167 282 MIMWYSPLGIACLIcGKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTA 361
Cdd:COG1301 182 WVMKLAPIGVFALI-AATVAKYGLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTS 259

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167 362 SSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASI 441
Cdd:COG1301 260 SSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGV 339

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|.
gi 78126167 442 PSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIV 492
Cdd:COG1301 340 PGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 43-502 5.22e-41

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 153.52  E-value: 5.22e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   43 KNLLLSLTvFGVILGAVCGGLLRLaapIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 121
Cdd:PRK01663   3 KPLYKSLY-FQVLVAIIIGILLGH---FYPELGAQMKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKAL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  122 VYYMSTTIIAAVLGVILVLAIHPGNpklkkqlgpgKKNDEVSSLDAfldlirnlfpenlvqacfQQIQTVTKKvlvappS 201
Cdd:PRK01663  79 LYFEIVSTIALIIGLIVVNVVQPGA----------GMNIDPATLDA------------------KAVAQYAAQ------A 124

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  202 EEANTTKAVISLLNETMNEApeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 281
Cdd:PRK01663 125 HEQGTVDFLMDIIPTTVVGA-------------FASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVN 190

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  282 MIMWYSPLG----IACLIcGKIiAIKDLevvaRQLGMYMITVIVGLIIhggiFLPLIYFVVTRKNPFSFFAgiFQAWITA 357
Cdd:PRK01663 191 MIMKLAPIGafgaMAFTI-GKY-GVGSL----VQLGQLIGCFYITCIL----FVFVVLGAIARLTGFSIFK--FIRYIKE 258

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  358 -----LGTASSAGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTAT 432
Cdd:PRK01663 259 ellivLGTSSSESALPRMMEKME-KLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLL 337

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 78126167  433 LASIGAASIPSAGLVTMLLILTAVG-LPTEDISLLVAVDWLLDRMRTSVNVVGDSFgAGIVYHLSKSELDT 502
Cdd:PRK01663 338 LTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGV-ATVVVAKWEKELDR 407
 
Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
46-495 1.57e-124

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 371.47  E-value: 1.57e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167    46 LLSLTVFGVILGAVCGGLLrlaapihPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAMVYY 124
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF-------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   125 MSTTIIAAVLGVILVLAIHPGNPKLKKQLGPgkKNDEVSSLDAFLDLIRNLFPENLVQACFQQiqtvtkkvlvappseea 204
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLALIAASL--KEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   205 nttkavisllnetmneapeetkivikkglefkdgmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIM 284
Cdd:pfam00375 135 -----------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVM 179

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   285 WYSPLGIACLICgKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSA 364
Cdd:pfam00375 180 KLAPIGVFALIA-NTVGTYGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSA 257

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   365 GTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSA 444
Cdd:pfam00375 258 ATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGG 337

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 78126167   445 GLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL 495
Cdd:pfam00375 338 GLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
43-492 4.47e-124

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 370.98  E-value: 4.47e-124
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  43 KNLLLSLTVFGVILGAVCGGLLrlaapiHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 121
Cdd:COG1301   2 KLSLTLQILIALVLGILLGLLL------PELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167 122 VYYMSTTIIAAVLGVILVLAIHPGNPkLKKQLGPGKKNDEVSSLDaFLDLIRNLFPENLVQAcfqqiqtvtkkvlvapps 201
Cdd:COG1301  76 LYFLVTTTIALVIGLVVANLFQPGAG-LNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------ 135

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167 202 eeanttkavisllnetmneapeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 281
Cdd:COG1301 136 ---------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVG 181

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167 282 MIMWYSPLGIACLIcGKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTA 361
Cdd:COG1301 182 WVMKLAPIGVFALI-AATVAKYGLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTS 259

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167 362 SSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASI 441
Cdd:COG1301 260 SSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGV 339

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|.
gi 78126167 442 PSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIV 492
Cdd:COG1301 340 PGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 43-502 5.22e-41

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 153.52  E-value: 5.22e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   43 KNLLLSLTvFGVILGAVCGGLLRLaapIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 121
Cdd:PRK01663   3 KPLYKSLY-FQVLVAIIIGILLGH---FYPELGAQMKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKAL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  122 VYYMSTTIIAAVLGVILVLAIHPGNpklkkqlgpgKKNDEVSSLDAfldlirnlfpenlvqacfQQIQTVTKKvlvappS 201
Cdd:PRK01663  79 LYFEIVSTIALIIGLIVVNVVQPGA----------GMNIDPATLDA------------------KAVAQYAAQ------A 124

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  202 EEANTTKAVISLLNETMNEApeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 281
Cdd:PRK01663 125 HEQGTVDFLMDIIPTTVVGA-------------FASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVN 190

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  282 MIMWYSPLG----IACLIcGKIiAIKDLevvaRQLGMYMITVIVGLIIhggiFLPLIYFVVTRKNPFSFFAgiFQAWITA 357
Cdd:PRK01663 191 MIMKLAPIGafgaMAFTI-GKY-GVGSL----VQLGQLIGCFYITCIL----FVFVVLGAIARLTGFSIFK--FIRYIKE 258

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  358 -----LGTASSAGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTAT 432
Cdd:PRK01663 259 ellivLGTSSSESALPRMMEKME-KLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLL 337

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 78126167  433 LASIGAASIPSAGLVTMLLILTAVG-LPTEDISLLVAVDWLLDRMRTSVNVVGDSFgAGIVYHLSKSELDT 502
Cdd:PRK01663 338 LTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGV-ATVVVAKWEKELDR 407
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 43-486 1.41e-39

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 149.91  E-value: 1.41e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   43 KNLLLSLT---VFGVILGAVCGGLLRLAAPIHPDVVMLIAFP-GDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLG 117
Cdd:PRK11283   2 KNIKFSLAwqiLIALVLGILLGAYLHYHSDSRDWLVSNLLSPaGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  118 TRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGP------GKKNDEVSSLD-AFLDLIRNLFPENLVQAcfqqiqt 190
Cdd:PRK11283  82 AKTIIYFEVITTVAIILGITLANVFQPGAGIDMSQLATvdiskyQSTTEEVQSHShGLMGTILSLIPTNIFAS------- 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  191 vtkkvlvappseeanttkavisllnetmneapeetkivIKKGlefkdgmNVLGLIGFFIAFGIAMGKMGEQAKL-MVEFF 269
Cdd:PRK11283 155 --------------------------------------MAKG-------EMLPIIFFSVLFGLGLSSLPATHREpLVTVF 189

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  270 NILNEIVMKLVIMIMWYSPLGIACLIcgkiiaikdlEVVARQLGMYMITVIVGLII--HGGI--FLPLIYFVVTRKNPFS 345
Cdd:PRK11283 190 RSVSETMFKVTHMVMRYAPVGVFALI----------AVTVANFGFASLWPLAKLVLlvYFAIlfFALVVLGIVARLCGLS 259

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  346 FFAGIF---QAWITALGTASSAGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGG 422
Cdd:PRK11283 260 IWILIRilkDELILAYSTASSETVLPRIIEKME-AYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIW 338

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 78126167  423 QIVTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDS 486
Cdd:PRK11283 339 QEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNA 402
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 51-485 3.27e-36

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 140.19  E-value: 3.27e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167   51 VFGVILGAVCGGLLrlaapihPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAMVYYMSTTI 129
Cdd:PRK13027  13 VIALVLGVALGAFF-------PHFAESLKPLGDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKVGRVGLKAVIYFEVMTT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  130 IAAVLGVILVLAIHPGNpklkkqlgpgKKNDEVSSLDAfldlirnlfpenlvqacfQQIQTVTKKVlvappSEEANTTKA 209
Cdd:PRK13027  86 IALVIGLVLAYLTGPGV----------GMNIDLRSLDA------------------ASLAGYAKNA-----QSLKGTAGF 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  210 VISLLNETMNEApeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPL 289
Cdd:PRK13027 133 LLKLIPTTAVDA-------------FAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVLFRIMGFIIKLAPL 198

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  290 GIACLIC---GKIiAIKDLevvaRQLGMYMITVIVGLIIhggiFLPLIYFVVTRKNPFSFFAGIF---QAWITALGTASS 363
Cdd:PRK13027 199 GVLGAIAfttGKY-GVGSL----KQLGMLVAVFYLTCFV----FVVVVLGAVMRLAGFSVFKLIRylrEELLIVLGTASS 269

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  364 AGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPS 443
Cdd:PRK13027 270 DAVLPQVMRKLE-HMGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSLVTSKGAHGIPG 348

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|...
gi 78126167  444 AGLVTMLLILTAVG-LPTEDISLLVAVDWLLDRMRTSVNVVGD 485
Cdd:PRK13027 349 SAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGN 391
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
 43-492 9.28e-26

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 110.30  E-value: 9.28e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  43 KNLLLSLTVF-GVILGAVCGGLLRLA----APIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRL 116
Cdd:COG1823  26 KHVSFSKRVFtGLGLGILFGLILQLIygagSPVIKQSIDWFNIVGNGYVRLLQMIVMPLVFVSILSAITKLkNASSLGKI 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167 117 GTRAMVYYMSTTIIAAVLGVILVLAIHpgnpklkkqlgpgkkndevssLDAfldlirnlfpENLVQAcfqqiqtvtkkvl 196
Cdd:COG1823 106 SGLIIGILLGTTAIAALVGILVALLFG---------------------LTA----------EGLTQG------------- 141

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167 197 vappseEANTTKavISLLNETMNEAPEETkiVIKKGLE------FKD--GMNVLGLIG--FFIAF-GIA----MGKMGEQ 261
Cdd:COG1823 142 ------AAETAR--GEALEERLGEVEDLS--LPQQILSfiptnpFADltGARPTSTIAvvIFAAFlGIAalglRRKKPEQ 211

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167 262 AKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICgKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIyfVVTRK 341
Cdd:COG1823 212 AETFLKGIDALQAIVMRLVRLVLRLTPYGVLALMT-KVVATSDFADIL-NLGKFVVASYVALIIMFIVHLLLL--ALAGL 287

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167 342 NPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTA-LYEAVAAIFIAQMNGV-IL 419
Cdd:COG1823 288 NPLTYFKKVWPVLTFAFTSRSSAGTIPLNIETQTKRLGVPEGIANFAASFGATIGQNGCAgIYPAMLAVMIAPTVGInPL 367

                       410       420       430       440       450       460       470
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 78126167 420 DGGQIVTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNvVGDSFGAGIV 492
Cdd:COG1823 368 DPSFILTLIAVVTISSFGVAGVGGGATFAALIVLSAMGLPVALAGLLISIEPLIDMGRTALN-VSGSMTAGTV 439
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
 240-486 8.64e-15

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 75.47  E-value: 8.64e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  240 NVLGLIGFFIAFGIAMGKMGEQAKlmvEFFNILNEIVMKLVIMIMWYSPLGIACLICgKIIAIKDLEVVArQLGMYMITV 319
Cdd:PRK14695  60 NYIGILSWAVIFGIAMREASKNSK---ELLKTIADVTSKIVEWIINLAPFGILGLVF-KTISDKGVGSLA-NYGILLVLL 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  320 IVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQ-AWITALGTASSAGTLPVTFRCLEDnLGIDKRVTRFVLPVGATINMD 398
Cdd:PRK14695 135 VTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCLRvSGVTAFFTRSSATNIPVNMKLCHD-LGLNPDTYSVSIPLGSTINMA 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  399 GTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRT 478
Cdd:PRK14695 214 GVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIGVIQD 293


                 ....*...
gi 78126167  479 SVNVVGDS 486
Cdd:PRK14695 294 SCETALNS 301
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 240-458 5.63e-12

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 67.58  E-value: 5.63e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  240 NVLGLIGFFIAFGIAMGKMGEQAKlmvEFFNILNEIVMKLVIMIMWYSPLGIACLICGkIIAIKDLEVVAR--QLGMYMI 317
Cdd:PRK13628 146 NYIGILAWAIGLGLALRHASDTTK---NVVNDLSEAVSQIVKWVIRFAPIGIFGLVAS-TLAETGFSALAGyaQLLAVLV 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167  318 T--VIVGLIIHggiflPLIYFVVTRKNPFSF-FAGIFQAWITALGTASSAGTLPVTFRCLEDnLGIDKRVTRFVLPVGAT 394
Cdd:PRK13628 222 GcmLFVALVVN-----PLIVFWKIRRNPYPLvFTCLRESGVTAFFTRSSAANIPVNMALCEK-LGLDEDTYSVSIPLGAT 295

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 78126167  395 INMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSAGLvtmLLILTAVGL 458
Cdd:PRK13628 296 INMAGAAITITVLTLAAVHTLGIPVDLPTALLLSVVAAISACGASGVAGGSL---LLIPLACSL 356
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
240-458 1.72e-10

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 63.27  E-value: 1.72e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167 240 NVLGLIGFFIAFGIAMGKMGEQAKLMvefFNILNEIVMKLVIMIMWYSPLGIACLICGkIIAIKDLEVvarqLGMY--MI 317
Cdd:COG3633 145 NYIGILAWAIGLGLALRHASDTTKTV---LSDLSDAVSKIVRWVIRFAPLGIFGLVAS-TVATTGFSA----LLGYahLL 216

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78126167 318 TVIVG------LIIHggiflPLIYFVVTRKNPFSF-FAGIFQAWITALGTASSAGTLPVTFRCLEDnLGIDKRVTRFVLP 390
Cdd:COG3633 217 AVLVGcmlfvaLVVN-----PLIVFLKIRRNPYPLvFTCLRESGITAFFTRSSAANIPVNMALCEK-LGLDEDTYSVSIP 290

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 78126167 391 VGATINMDGtalyeavAAIFIAQMN-------GVILDGGQIVTVSLTATLASIGAASIPSAGLvtmLLILTAVGL 458
Cdd:COG3633 291 LGATINMAG-------AAITITVLTlaavhtlGIEVDLPTALLLSVVAAVSACGASGVAGGSL---LLIPLACSL 355
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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