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Conserved domains on  [gi|148539593|ref|NP_060452|]
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sushi domain-containing protein 4 isoform a precursor [Homo sapiens]

Protein Classification

beta-2-glycoprotein 1( domain architecture ID 13269567)

beta-2-glycoprotein 1 is a heavily glycosylated plasma membrane-adhesion protein, which plays a role in blood coagulation and removal of apoptotic bodies

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02639 super family cl31493
EEV host range protein; Provisional
 30-238 1.31e-13

EEV host range protein; Provisional


The actual alignment was detected with superfamily member PHA02639:

Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 71.23  E-value: 1.31e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593  30 LAVILWFQLALCFgpaqlTGGFDDLqVCADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLgW 109
Cdd:PHA02639   1 MKIILYLFIGVCY-----VHGVKSI-YCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAI-W 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593 110 iPSDNSICVQEDCR-IPQIEDAEIHNK--TYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWN-NLPICQ--GCLRP 183
Cdd:PHA02639  74 -SNKAPFCMLKECNdPPSIINGKIYNKreMYKVGDEIYYVCNEHKGVQYSLVGNEKITCIQDKSWKpDPPICKmiNCRFP 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 148539593 184 lASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCL 238
Cdd:PHA02639 153 -ALQNGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 243-297 3.49e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


:

Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 3.49e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 148539593   243 CPLPPMVSHGDFVCHPRPcerYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEWFPS 297
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGS-STITCLeNGTWSPP 52
 
Name Accession Description Interval E-value
PHA02639 PHA02639
EEV host range protein; Provisional
 30-238 1.31e-13

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 71.23  E-value: 1.31e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593  30 LAVILWFQLALCFgpaqlTGGFDDLqVCADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLgW 109
Cdd:PHA02639   1 MKIILYLFIGVCY-----VHGVKSI-YCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAI-W 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593 110 iPSDNSICVQEDCR-IPQIEDAEIHNK--TYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWN-NLPICQ--GCLRP 183
Cdd:PHA02639  74 -SNKAPFCMLKECNdPPSIINGKIYNKreMYKVGDEIYYVCNEHKGVQYSLVGNEKITCIQDKSWKpDPPICKmiNCRFP 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 148539593 184 lASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCL 238
Cdd:PHA02639 153 -ALQNGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 180-237 9.23e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.17  E-value: 9.23e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 148539593 180 CLRPLASSNGYVNISelQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Cdd:cd00033    1 CPPPPVPENGTVTGS--KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 180-237 1.73e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.38  E-value: 1.73e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 148539593   180 CLRPLASSNGYVNISelQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Cdd:smart00032   1 CPPPPDIENGTVTSS--SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
190-237 3.93e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.50  E-value: 3.93e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 148539593  190 YVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Cdd:pfam00084   9 NGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 243-297 3.49e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 3.49e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 148539593   243 CPLPPMVSHGDFVCHPRPcerYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEWFPS 297
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGS-STITCLeNGTWSPP 52
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 243-294 7.50e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.00  E-value: 7.50e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 148539593 243 CPLPPMVSHGDFVCHPrpcERYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEW 294
Cdd:cd00033    1 CPPPPVPENGTVTGSK---GSYSYGSTVTYSCNEGYTLVGS-STITCTeNGGW 49
Sushi pfam00084
Sushi repeat (SCR repeat);
243-294 5.50e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 43.64  E-value: 5.50e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 148539593  243 CPLPPMVSHGDFVChprPCERYNHGTVVEFYCDPGYSLTSDYKyITCQ-YGEW 294
Cdd:pfam00084   1 CPPPPDIPNGKVSA---TKNEYNYGASVSYECDPGYRLVGSPT-ITCQeDGTW 49
 
Name Accession Description Interval E-value
PHA02639 PHA02639
EEV host range protein; Provisional
 30-238 1.31e-13

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 71.23  E-value: 1.31e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593  30 LAVILWFQLALCFgpaqlTGGFDDLqVCADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLgW 109
Cdd:PHA02639   1 MKIILYLFIGVCY-----VHGVKSI-YCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAI-W 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593 110 iPSDNSICVQEDCR-IPQIEDAEIHNK--TYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWN-NLPICQ--GCLRP 183
Cdd:PHA02639  74 -SNKAPFCMLKECNdPPSIINGKIYNKreMYKVGDEIYYVCNEHKGVQYSLVGNEKITCIQDKSWKpDPPICKmiNCRFP 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 148539593 184 lASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCL 238
Cdd:PHA02639 153 -ALQNGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 57-238 1.40e-12

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 67.76  E-value: 1.40e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593  57 CADPGIPENGfRTPSGGVFFeGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPsDNSICVQEDCRIPQIEDAEIHN-- 134
Cdd:PHA02927  86 CPSPRDIDNG-QLDIGGVDF-GSSITYSCNSGYQLIGESKSYCELGSTGSMVWNP-EAPICESVKCQSPPSISNGRHNgy 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593 135 -KTYRHGEKLIITCHEGFKIrypdLHNMVSLCrDDGTWNNLPICQ--GCLRPlASSNGYVNiSELQTSFPVGTVISYRCF 211
Cdd:PHA02927 163 eDFYTDGSVVTYSCNSGYSL----IGNSGVLC-SGGEWSDPPTCQivKCPHP-TISNGYLS-SGFKRSYSYNDNVDFKCK 235

                        170       180
                 ....*....|....*....|....*..
gi 148539593 212 PGFKLDGSAYLECLQNLIWSSSPPRCL 238
Cdd:PHA02927 236 YGYKLSGSSSSTCSPGNTWQPELPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 180-237 9.23e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.17  E-value: 9.23e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 148539593 180 CLRPLASSNGYVNISelQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Cdd:cd00033    1 CPPPPVPENGTVTGS--KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 180-237 1.73e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.38  E-value: 1.73e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 148539593   180 CLRPLASSNGYVNISelQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Cdd:smart00032   1 CPPPPDIENGTVTSS--SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 134-294 5.02e-10

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 60.05  E-value: 5.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593 134 NKTYRHGEKLIITCHEGFkiRYPDLHNMVSLCRDDG-TWNNLPICQGCLRPLASSNGYVNISELQtsfpVGTVISYRCFP 212
Cdd:PHA02927  41 NANYNIGDTIEYLCLPGY--RKQKMGPIYAKCTGTGwTLFNQCIKRRCPSPRDIDNGQLDIGGVD----FGSSITYSCNS 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593 213 GFKLDGSAYLEC----LQNLIWSSSPPRCLALEvCPLPPMVSHGDfvcHPRPCERYNHGTVVEFYCDPGYSLTSDYKyIT 288
Cdd:PHA02927 115 GYQLIGESKSYCelgsTGSMVWNPEAPICESVK-CQSPPSISNGR---HNGYEDFYTDGSVVTYSCNSGYSLIGNSG-VL 189


                 ....*.
gi 148539593 289 CQYGEW 294
Cdd:PHA02927 190 CSGGEW 195
PHA02817 PHA02817
EEV Host range protein; Provisional
 115-237 2.00e-09

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 57.64  E-value: 2.00e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593 115 SICVQEDCRIP-QIEDAEIHNK--TYRHGEKLIITCHEGFK-IRYPDLHNMVSLCRDDGTWN-NLPICQ--GCLRPlASS 187
Cdd:PHA02817  17 SLCDLNKCCYPpSIKNGYIYNKktEYNIGSNVTFFCGNNTRgVRYTLVGEKNIICEKDGKWNkEFPVCKiiRCRFP-ALQ 95

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 148539593 188 NGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Cdd:PHA02817  96 NGFVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPIC 145
Sushi pfam00084
Sushi repeat (SCR repeat);
190-237 3.93e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.50  E-value: 3.93e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 148539593  190 YVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Cdd:pfam00084   9 NGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 243-297 3.49e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 3.49e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 148539593   243 CPLPPMVSHGDFVCHPRPcerYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEWFPS 297
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGS-STITCLeNGTWSPP 52
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 243-294 7.50e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.00  E-value: 7.50e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 148539593 243 CPLPPMVSHGDFVCHPrpcERYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEW 294
Cdd:cd00033    1 CPPPPVPENGTVTGSK---GSYSYGSTVTYSCNEGYTLVGS-STITCTeNGGW 49
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 57-102 1.50e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 48.23  E-value: 1.50e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 148539593  57 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKH 102
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN 46
PHA02639 PHA02639
EEV host range protein; Provisional
 180-296 7.39e-07

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.82  E-value: 7.39e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593 180 CLRPLASSNGYvnISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQ---NLIWSSSPPRCLaLEVCPLPPMVSHGDfVC 256
Cdd:PHA02639  22 CDKPDDISNGF--ITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKdknNAIWSNKAPFCM-LKECNDPPSIINGK-IY 97

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 148539593 257 HPRpcERYNHGTVVEFYCDP----GYSLTSDYKYITCQYGEWFP 296
Cdd:PHA02639  98 NKR--EMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKSWKP 139
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 57-100 9.68e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.60  E-value: 9.68e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 148539593    57 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCL 100
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCL 44
PHA02831 PHA02831
EEV host range protein; Provisional
 104-238 1.16e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 49.99  E-value: 1.16e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593 104 NGTlgWipSDNSICV-QEDCRIP-QIEDAEIHNKT--YRHGEKLIITCHEGFKIRYPDLHNMVSLCRDdGTW-NNLPICQ 178
Cdd:PHA02831  63 NGS--W--STKNMCIgKRNCKDPvTILNGYIKNKKdqYSFGDSVTYACKVNKLEKYSIVGNETVKCIN-KQWvPKYPVCK 137

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 148539593 179 --GCLRPlASSNGYVNIseLQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCL 238
Cdd:PHA02831 138 liRCKYP-ALQNGFLNV--FEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCV 196
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 54-296 4.06e-06

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 48.50  E-value: 4.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593  54 LQVCADPGIP-----ENGFRTPSGGVFFEGSVARFHCQDGFKLK--GATKRLClkhfNGTlGWIPSDNsiCVQEDCRIPQ 126
Cdd:PHA02927  18 LSCCTIPSRPinmkfKNSVETDANANYNIGDTIEYLCLPGYRKQkmGPIYAKC----TGT-GWTLFNQ--CIKRRCPSPR 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593 127 -IEDAEIHNKTYRHGEKLIITCHEGFKIrypdLHNMVSLCRDDGT----WN-NLPICQG--CLRPLASSNGYVNISElqT 198
Cdd:PHA02927  91 dIDNGQLDIGGVDFGSSITYSCNSGYQL----IGESKSYCELGSTgsmvWNpEAPICESvkCQSPPSISNGRHNGYE--D 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593 199 SFPVGTVISYRCFPGFKLDGSAYLEClQNLIWSSsPPRCLALEvCPlPPMVSHGDFVCHPRpcERYNHGTVVEFYCDPGY 278
Cdd:PHA02927 165 FYTDGSVVTYSCNSGYSLIGNSGVLC-SGGEWSD-PPTCQIVK-CP-HPTISNGYLSSGFK--RSYSYNDNVDFKCKYGY 238

                        250
                 ....*....|....*....
gi 148539593 279 SLTSDYKYiTCQYGE-WFP 296
Cdd:PHA02927 239 KLSGSSSS-TCSPGNtWQP 256
Sushi pfam00084
Sushi repeat (SCR repeat);
243-294 5.50e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 43.64  E-value: 5.50e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 148539593  243 CPLPPMVSHGDFVChprPCERYNHGTVVEFYCDPGYSLTSDYKyITCQ-YGEW 294
Cdd:pfam00084   1 CPPPPDIPNGKVSA---TKNEYNYGASVSYECDPGYRLVGSPT-ITCQeDGTW 49
Sushi pfam00084
Sushi repeat (SCR repeat);
57-104 5.77e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 43.64  E-value: 5.77e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 148539593   57 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFN 104
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGT 48
PHA02831 PHA02831
EEV host range protein; Provisional
 115-304 9.17e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 47.29  E-value: 9.17e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593 115 SICV--QEDCRIPQIEDAEihNKTYRHGEKLIITCHEGFkirypdlhNMVSLCRDDGTWNNLPICQG---CLRPLASSNG 189
Cdd:PHA02831  18 CICVfnKNDAKYSNVDSYE--NKVYEENENLEYKCNNNF--------DKVFVTCNNGSWSTKNMCIGkrnCKDPVTILNG 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593 190 YVNISELQTSFpvGTVISYRC----FPGFKLDGSAYLECLqNLIWSSSPPRClALEVCPLPPMvSHGDFVCHPRpceRYN 265
Cdd:PHA02831  88 YIKNKKDQYSF--GDSVTYACkvnkLEKYSIVGNETVKCI-NKQWVPKYPVC-KLIRCKYPAL-QNGFLNVFEK---KFY 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 148539593 266 HGTVVEFYCDPGY----SLTSdykyiTCQYGE-WFPSYQvYCIK 304
Cdd:PHA02831 160 YGDIVNFKCKKGFillgSSVS-----TCDINSiWYPGIP-KCVK 197
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 92-238 1.52e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 47.00  E-value: 1.52e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593  92 KGATKRLCLKHFNGTLGWipSDNSICVQEDCRIPQIEDAEIH--NKTYRHGEKLIITCHEGFKIRYPDLHNMVSlcrddG 169
Cdd:PHA02954 102 KDETKYFRCEEKNGNTSW--NDTVTCPNAECQPLQLEHGSCQpvKEKYSFGEHITINCDVGYEVIGASYISCTA-----N 174

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 148539593 170 TWNNLPICQGCLRPLASSNGYVNISelqtSFPVGTVISYRCFPGFKLDGSAYLECLQNLiWSSSPPRCL 238
Cdd:PHA02954 175 SWNVIPSCQQKCDIPSLSNGLISGS----TFSIGGVIHLSCKSGFTLTGSPSSTCIDGK-WNPVLPICV 238
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 125-177 1.53e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 36.74  E-value: 1.53e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 148539593   125 PQIEDAEI--HNKTYRHGEKLIITCHEGFKIRYPDlhnmVSLCRDDGTWNN-LPIC 177
Cdd:smart00032   5 PDIENGTVtsSSGTYSYGDTVTYSCDPGYTLIGSS----TITCLENGTWSPpPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 125-178 7.24e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 34.75  E-value: 7.24e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 148539593 125 PQIEDAEI--HNKTYRHGEKLIITCHEGFKIRYPDlhnmVSLCRDDGTWNN-LPICQ 178
Cdd:cd00033    5 PVPENGTVtgSKGSYSYGSTVTYSCNEGYTLVGSS----TITCTENGGWSPpPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
122-177 9.08e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 34.40  E-value: 9.08e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 148539593  122 CRIPQ-IEDAEIH--NKTYRHGEKLIITCHEGFkiRYPDlhNMVSLCRDDGTWNNL-PIC 177
Cdd:pfam00084   1 CPPPPdIPNGKVSatKNEYNYGASVSYECDPGY--RLVG--SPTITCQEDGTWSPPfPEC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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