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Conserved domains on  [gi|20127150|ref|NP_061218|]
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golgin subfamily A member 4 isoform 1 [Mus musculus]

Protein Classification

GRIP and coiled-coil domain-containing protein; GRIP and coiled-coil domain-containing protein; GRIP domain-containing protein; GRIP domain-containing protein( domain architecture ID 13528997)

GRIP (golgin-97, RanBP2alpha, Imh1p and p230/golgin-245) domain-containing protein; similar to Eremothecium gossypii golgin IMH1 which is involved in vesicular transport between an endosomal compartment and the Golgi apparatus; GRIP (golgin-97, RanBP2alpha, Imh1p and p230/golgin-245) domain-containing protein; similar to Eremothecium gossypii golgin IMH1 which is involved in vesicular transport between an endosomal compartment and the Golgi apparatus; GRIP and coiled-coil domain-containing protein similar to Mus musculus GRIP and coiled-coil domain-containing protein 1 that is probably involved in maintaining Golgi structure; GRIP domain-containing protein; GRIP and coiled-coil domain-containing protein similar to Mus musculus GRIP and coiled-coil domain-containing protein 1 that is probably involved in maintaining Golgi structure

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 401-982 7.12e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.86  E-value: 7.12e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  401 EDEIAQLRSHIKQMTTQGE------ELREQKEKSE-RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV-ERASEEER 472
Cdd:COG1196  192 EDILGELERQLEPLERQAEkaeryrELKEELKELEaELLLLKLRELEAELEELEAELEELEAELEELEAELaELEAELEE 271

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  473 LRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQ 552
Cdd:COG1196  272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  553 ESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKHNKELTALAEQH 632
Cdd:COG1196  352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE-ALLERLERLEEELEELEEAL 430

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  633 RTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDK---KQMELESV 709
Cdd:COG1196  431 AELEEEEEEEEEAL--EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLeaeADYEGFLE 508

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  710 SSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQ--QELTVRRAEKALKDELSRLGALLDE 787
Cdd:COG1196  509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRARAAL 588

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  788 RDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTkqvvEMET 867
Cdd:COG1196  589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG----SLTG 664

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  868 HKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTL 947
Cdd:COG1196  665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                        570       580       590
                 ....*....|....*....|....*....|....*
gi 20127150  948 SSKEESISILHEEYETKFKNQEKRMEKIKQKAKEM 982
Cdd:COG1196  745 EELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 693-1299 2.99e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.39  E-value: 2.99e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  693 EKTLEKLDKKQMELESVSSELSEalrardqLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEL--TVRRA 770
Cdd:COG1196  175 EEAERKLEATEENLERLEDILGE-------LERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAE 247

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  771 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLD 850
Cdd:COG1196  248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  851 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENIIL 930
Cdd:COG1196  328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELE 406

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  931 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK-KELENTVLELSQ 1009
Cdd:COG1196  407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAlLEAALAELLEEL 486

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1010 KEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQR----KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKE 1085
Cdd:COG1196  487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1086 QGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQsqvekleADLGCSLSEK 1165
Cdd:COG1196  567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRA 639

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1166 LSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEA 1245
Cdd:COG1196  640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                        570       580       590       600       610
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 20127150 1246 KTNELV--CTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEE 1299
Cdd:COG1196  720 ELEEEAleEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1019-1713 3.91e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.48  E-value: 3.91e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1019 LEMAQANSAGISDTVSRLEEN-QRQQIESLTGAHQRKLDDVIEAWEKKLS----QQAAELRDKHAEQMEEKEQGLGELRQ 1093
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlKSLERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1094 KVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELA 1173
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1174 ELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAsQLDSRCERTKALLEAKTNELVCT 1253
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1254 SRDKADAI----LARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1329
Cdd:TIGR02168  420 QQEIEELLkkleEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1330 GLLTEKEALQQEGGQQRQAASEKESCITQLKKE----------LAENINAVtlLREELSEKKSEIASLSKQLSDLGAQLE 1399
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1400 SSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDAL----------SKEKMSALEQV--------------DHWSN 1455
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvVDDLDNALELAkklrpgyrivtldgDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1456 KFSEWK----------------KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV 1519
Cdd:TIGR02168  658 GGVITGgsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1520 RKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT---EHSGLVQRLQHLEE 1586
Cdd:TIGR02168  738 LEAEVEQLEeriaqlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1587 LGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKALEDKLELESAAKVELKRKAEQKIAAIR 1666
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 20127150   1667 KQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1713
Cdd:TIGR02168  894 SELEELSEE-----LRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1489-2157 3.95e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.01  E-value: 3.95e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1489 AREKEEQICLLKEDLDRQNKKFECLKGEmevrKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQ 1568
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1569 qrdtEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgELKALEDKLELES 1648
Cdd:TIGR02168  296 ----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------ELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1649 AAKVELKRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQ 1728
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1729 SVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--- 1805
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkal 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1806 ---------LIGCLPEELEEKMKCSLIVSQPMGE-----ETGNNTGVKQNWAS-------------VVDSVQKTLQEKEL 1858
Cdd:TIGR02168  512 lknqsglsgILGVLSELISVDEGYEAAIEAALGGrlqavVVENLNAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1859 TCQALEQRVKELESDLVRERGAHRLEVEKL---------------TLKYEKSQSSQQEMDGE--NKCVEVLEDRPEENSQ 1921
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnaleLAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1922 SHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKH 2001
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   2002 TSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDAREEEM 2081
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAAN-LRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   2082 TGKVTDLQTQLEELQKKYQQRLEQEESTKDSV-----TILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2156
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIeeleeLIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   .
gi 20127150   2157 A 2157
Cdd:TIGR02168  910 R 910
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2182-2225 4.35e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


:

Pssm-ID: 197860  Cd Length: 46  Bit Score: 51.07  E-value: 4.35e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 20127150    2182 PTEFEYLRKVMFEYMMGRET--KTMAKVITTVLKFPDDQAQKILER 2225
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
CCDC158 super family cl37899
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 157-552 3.41e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


The actual alignment was detected with superfamily member pfam15921:

Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.80  E-value: 3.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    157 REQLLQRLRRMERSLSSY-RGKYSELVTAFQTLQREKKKLQGILSQ--SQDKSLRRISELREELQMDQQAKKHLQDEFDA 233
Cdd:pfam15921  424 RNMEVQRLEALLKAMKSEcQGQMERQMAAIQGKNESLEKVSSLTAQleSTKEMLRKVVEELTAKKMTLESSERTVSDLTA 503

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    234 CLEEKDQYISVLQTQVSLLKQRLQNGPMNVDAPKPlpPGELQAEVHGDTEKMEGVGEPVGggtsaKTLEMLQQRVkrqEN 313
Cdd:pfam15921  504 SLQEKERAIEATNAEITKLRSRVDLKLQELQHLKN--EGDHLRNVQTECEALKLQMAEKD-----KVIEILRQQI---EN 573

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    314 LLQrckeTIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELH-----------------MAEKTKLITQLRDAKNLIE 376
Cdd:pfam15921  574 MTQ----LVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKdkkdakirelearvsdlELEKVKLVNAGSERLRAVK 649

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    377 QLEQDKGMVITETKRQMLETLELKED-EIAQ--LRSHIKQMTTQGEELREQKeKSERAAFEELEKALSTAQKTEDAQRRM 453
Cdd:pfam15921  650 DIKQERDQLLNEVKTSRNELNSLSEDyEVLKrnFRNKSEEMETTTNKLKMQL-KSAQSELEQTRNTLKSMEGSDGHAMKV 728

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    454 KMEMDEQMKAVERASEEERLRLQhelsrVRQEAASMAKKNSEEQVAALQKLHAE--ELASKEQELSRRLE---ARERELQ 528
Cdd:pfam15921  729 AMGMQKQITAKRGQIDALQSKIQ-----FLEEAMTNANKEKHFLKEEKNKLSQElsTVATEKNKMAGELEvlrSQERRLK 803

                          410       420       430
                   ....*....|....*....|....*....|
gi 20127150    529 EQ---MRIALEKSRSEYLK---LTQEKEQQ 552
Cdd:pfam15921  804 EKvanMEVALDKASLQFAEcqdIIQRQEQE 833
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 401-982 7.12e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.86  E-value: 7.12e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  401 EDEIAQLRSHIKQMTTQGE------ELREQKEKSE-RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV-ERASEEER 472
Cdd:COG1196  192 EDILGELERQLEPLERQAEkaeryrELKEELKELEaELLLLKLRELEAELEELEAELEELEAELEELEAELaELEAELEE 271

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  473 LRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQ 552
Cdd:COG1196  272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  553 ESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKHNKELTALAEQH 632
Cdd:COG1196  352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE-ALLERLERLEEELEELEEAL 430

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  633 RTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDK---KQMELESV 709
Cdd:COG1196  431 AELEEEEEEEEEAL--EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLeaeADYEGFLE 508

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  710 SSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQ--QELTVRRAEKALKDELSRLGALLDE 787
Cdd:COG1196  509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRARAAL 588

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  788 RDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTkqvvEMET 867
Cdd:COG1196  589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG----SLTG 664

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  868 HKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTL 947
Cdd:COG1196  665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                        570       580       590
                 ....*....|....*....|....*....|....*
gi 20127150  948 SSKEESISILHEEYETKFKNQEKRMEKIKQKAKEM 982
Cdd:COG1196  745 EELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 693-1299 2.99e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.39  E-value: 2.99e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  693 EKTLEKLDKKQMELESVSSELSEalrardqLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEL--TVRRA 770
Cdd:COG1196  175 EEAERKLEATEENLERLEDILGE-------LERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAE 247

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  771 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLD 850
Cdd:COG1196  248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  851 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENIIL 930
Cdd:COG1196  328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELE 406

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  931 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK-KELENTVLELSQ 1009
Cdd:COG1196  407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAlLEAALAELLEEL 486

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1010 KEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQR----KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKE 1085
Cdd:COG1196  487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1086 QGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQsqvekleADLGCSLSEK 1165
Cdd:COG1196  567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRA 639

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1166 LSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEA 1245
Cdd:COG1196  640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                        570       580       590       600       610
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 20127150 1246 KTNELV--CTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEE 1299
Cdd:COG1196  720 ELEEEAleEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 693-1399 7.22e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 94.36  E-value: 7.22e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    693 EKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRGDADKMkQALEAELEEQRRHHQREVGSISEQQELTVRRAEK 772
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRRE----REKAERY-QALLKEKREYEGYELLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    773 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQAL-AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL 851
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVkEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    852 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQ----RSELEEKVRSLAQLQDsQLKNSTVEKEQA---RQSLME 924
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEledlRAELEEVDKEFAETRD-ELKDYREKLEKLkreINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    925 KENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEA---KLKKELE 1001
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEeydRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1002 NTVLELSQKEKQ---------FNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAE 1072
Cdd:TIGR02169  487 KLQRELAEAEAQaraseervrGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIEL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1073 LRDKHA--------EQMEEKEQGLGELRQK------VRIVQSEKEELTKEVARLKEAVSGQDVALA----------GLQG 1128
Cdd:TIGR02169  567 LKRRKAgratflplNKMRDERRDLSILSEDgvigfaVDLVEFDPKYEPAFKYVFGDTLVVEDIEAArrlmgkyrmvTLEG 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1129 QLEQKSAVIVSLSERESQLQS-------QVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQ 1201
Cdd:TIGR02169  647 ELFEKSGAMTGGSRAPRGGILfsrsepaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1202 SCKSLHELSK----------KSLEDKSLNLKSLLEELASQLDSRcERTKALLEAKTNELvctsrdKADAILARLSQCQRH 1271
Cdd:TIGR02169  727 QLEQEEEKLKerleeleedlSSLEQEIENVKSELKELEARIEEL-EEDLHKLEEALNDL------EARLSHSRIPEIQAE 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1272 TATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASE 1351
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRD 879

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 20127150   1352 KESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLE 1399
Cdd:TIGR02169  880 LESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 388-1176 3.46e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 3.46e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    388 ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSER-----AAFEELEKALSTAQKTEDAQRRMKMEMDEQMK 462
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERykelkAELRELELALLVLRLEELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    463 AVERASEEERLR-LQHELSRVRQEAASMakknsEEQVAALQKlhaeELASKEQELSrRLEARERELQEQMRIALEKsrSE 541
Cdd:TIGR02168  252 EEELEELTAELQeLEEKLEELRLEVSEL-----EEEIEELQK----ELYALANEIS-RLEQQKQILRERLANLERQ--LE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    542 YLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKH 621
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA-QLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    622 NKELTALaeqhRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALlkekeslfqahiqdmnEKTLEKLDK 701
Cdd:TIGR02168  399 NNEIERL----EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL----------------EELQEELER 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    702 KQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRR-----HHQRE----VGSISEQ---------- 762
Cdd:TIGR02168  459 LEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGvkallKNQSGlsgiLGVLSELisvdegyeaa 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    763 ---------QELTVRRAEKALKD---------------ELSRL-GALLDERDEHLRERQARVQDLEAHLQKSAGE----- 812
Cdd:TIGR02168  539 ieaalggrlQAVVVENLNAAKKAiaflkqnelgrvtflPLDSIkGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    813 ------------LQQALAKLDLLHSEQSAAREQA------GAYEEQLAQMQQKVLDLETEKSLLTKQVVEMEthkkhvcE 874
Cdd:TIGR02168  619 syllggvlvvddLDNALELAKKLRPGYRIVTLDGdlvrpgGVITGGSAKTNSSILERRREIEELEEKIEELE-------E 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    875 ELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENiILQMREEQAKEIEILKQTLSSKEESI 954
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ-LEERIAQLSKELTELEAEIEELEERL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    955 silhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEkqfnaQILEMAQANSAGISDTVS 1034
Cdd:TIGR02168  771 ----EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR-----ERLESLERRIAATERRLE 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1035 RLE---ENQRQQIESLTGAhQRKLDDVIEAWEKKLsQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVAR 1111
Cdd:TIGR02168  842 DLEeqiEELSEDIESLAAE-IEELEELIEELESEL-EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 20127150   1112 LKEAVSGQDVALAGLQGQLEQksaVIVSLSERESQLQSQVEKLEADLGCSLSEklsLQEELAELK 1176
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDN---LQERLSEEYSLTLEEAEALENKIEDDEEE---ARRRLKRLE 978
PTZ00121 PTZ00121
MAEBL; Provisional
 335-1064 2.86e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 85.96  E-value: 2.86e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   335 EKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAknlieqlEQDKGMVITETKRQMLETLELKEDEIAQLRSHIKQM 414
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKA 1184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   415 --TTQGEELR--EQKEKSERAAFEELEKALSTAQKTEDAQRRMKM-EMDEQMKAVERASEEERLRLQHELsRVRQEAASM 489
Cdd:PTZ00121 1185 eeVRKAEELRkaEDARKAEAARKAEEERKAEEARKAEDAKKAEAVkKAEEAKKDAEEAKKAEEERNNEEI-RKFEEARMA 1263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   490 AKKNSEEQVAALQKLHAEELaSKEQELSRRLEARE----RELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKK 565
Cdd:PTZ00121 1264 HFARRQAAIKAEEARKADEL-KKAEEKKKADEAKKaeekKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAK 1342

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   566 AILTESENKLQELGQEAEAYRtrilELETSLEKSLQESKTQSEhlAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDS 645
Cdd:PTZ00121 1343 KAAEAAKAEAEAAADEAEAAE----EKAEAAEKKKEEAKKKAD--AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA 1416

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   646 LWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLD----KKQMELESVSSELSEALRARD 721
Cdd:PTZ00121 1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKadeaKKKAEEAKKADEAKKKAEEAK 1496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   722 QLAEElsvLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARvqd 801
Cdd:PTZ00121 1497 KKADE---AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK--- 1570

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   802 leahlqKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRA 881
Cdd:PTZ00121 1571 ------KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE 1644

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   882 QVQQLERQRSELEE-KVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEesisilhEE 960
Cdd:PTZ00121 1645 EKKKAEELKKAEEEnKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK-------KK 1717

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   961 YETKFKNQEKRMEKIKQKAKEMQETKKKLldQEAKLKKELENTVLELSQKEKQfnaQILEMAQANSAGISDTVSRLEENQ 1040
Cdd:PTZ00121 1718 AEELKKAEEENKIKAEEAKKEAEEDKKKA--EEAKKDEEEKKKIAHLKKEEEK---KAEEIRKEKEAVIEEELDEEDEKR 1792

                         730       740
                  ....*....|....*....|....
gi 20127150  1041 RQQIESLTGAHQRKLDDVIEAWEK 1064
Cdd:PTZ00121 1793 RMEVDKKIKDIFDNFANIIEGGKE 1816
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 575-1215 8.03e-14

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 77.47  E-value: 8.03e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    575 LQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvhleaekNKHNKELTALAEQHRTEVEGLQQQQDSLWTERlQSL 654
Cdd:pfam15921  226 LRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLL-------QQHQDRIEQLISEHEVEITGLTEKASSARSQA-NSI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    655 SQQHQAAVEELREKYQQEKDAL--LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRG 732
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMRQLsdLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQE----SG 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    733 DADKMKQALEAELeeqrrhHQREvgsiseqQELTVRRAE-KALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAG 811
Cdd:pfam15921  374 NLDDQLQKLLADL------HKRE-------KELSLEKEQnKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKS 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    812 ELQqalakldllhseqsaareqaGAYEEQLAQMQQKVLDLETEKSLlTKQVVEMETHKKHVCEELDAQRAQVQQLERQRS 891
Cdd:pfam15921  441 ECQ--------------------GQMERQMAAIQGKNESLEKVSSL-TAQLESTKEMLRKVVEELTAKKMTLESSERTVS 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    892 EL----EEKVRSLaqlqdsQLKNSTVEKEQARQSLMEKENIILQMREEQAK----EIEILKQTLSSKEESISILHEEyet 963
Cdd:pfam15921  500 DLtaslQEKERAI------EATNAEITKLRSRVDLKLQELQHLKNEGDHLRnvqtECEALKLQMAEKDKVIEILRQQ--- 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    964 kfknqekrMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQ----------KEKQFNAQI--LEMAQANSAGISD 1031
Cdd:pfam15921  571 --------IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkkdaKIRELEARVsdLELEKVKLVNAGS 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1032 TVSRLEENQRQQIESLTGAHQRKLDDVieaweKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEElTKEVAR 1111
Cdd:pfam15921  643 ERLRAVKDIKQERDQLLNEVKTSRNEL-----NSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQ-TRNTLK 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1112 LKEAVSGQDVALA-GLQGQLEQKSAVIVSL----------------------------SERESQLQSQVEKLEADLGCSL 1162
Cdd:pfam15921  717 SMEGSDGHAMKVAmGMQKQITAKRGQIDALqskiqfleeamtnankekhflkeeknklSQELSTVATEKNKMAGELEVLR 796

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 20127150   1163 SEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLE 1215
Cdd:pfam15921  797 SQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1019-1713 3.91e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.48  E-value: 3.91e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1019 LEMAQANSAGISDTVSRLEEN-QRQQIESLTGAHQRKLDDVIEAWEKKLS----QQAAELRDKHAEQMEEKEQGLGELRQ 1093
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlKSLERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1094 KVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELA 1173
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1174 ELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAsQLDSRCERTKALLEAKTNELVCT 1253
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1254 SRDKADAI----LARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1329
Cdd:TIGR02168  420 QQEIEELLkkleEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1330 GLLTEKEALQQEGGQQRQAASEKESCITQLKKE----------LAENINAVtlLREELSEKKSEIASLSKQLSDLGAQLE 1399
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1400 SSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDAL----------SKEKMSALEQV--------------DHWSN 1455
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvVDDLDNALELAkklrpgyrivtldgDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1456 KFSEWK----------------KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV 1519
Cdd:TIGR02168  658 GGVITGgsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1520 RKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT---EHSGLVQRLQHLEE 1586
Cdd:TIGR02168  738 LEAEVEQLEeriaqlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1587 LGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKALEDKLELESAAKVELKRKAEQKIAAIR 1666
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 20127150   1667 KQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1713
Cdd:TIGR02168  894 SELEELSEE-----LRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1489-2157 3.95e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.01  E-value: 3.95e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1489 AREKEEQICLLKEDLDRQNKKFECLKGEmevrKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQ 1568
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1569 qrdtEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgELKALEDKLELES 1648
Cdd:TIGR02168  296 ----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------ELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1649 AAKVELKRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQ 1728
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1729 SVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--- 1805
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkal 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1806 ---------LIGCLPEELEEKMKCSLIVSQPMGE-----ETGNNTGVKQNWAS-------------VVDSVQKTLQEKEL 1858
Cdd:TIGR02168  512 lknqsglsgILGVLSELISVDEGYEAAIEAALGGrlqavVVENLNAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1859 TCQALEQRVKELESDLVRERGAHRLEVEKL---------------TLKYEKSQSSQQEMDGE--NKCVEVLEDRPEENSQ 1921
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnaleLAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1922 SHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKH 2001
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   2002 TSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDAREEEM 2081
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAAN-LRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   2082 TGKVTDLQTQLEELQKKYQQRLEQEESTKDSV-----TILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2156
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIeeleeLIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   .
gi 20127150   2157 A 2157
Cdd:TIGR02168  910 R 910
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1850-2154 3.78e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 3.78e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1850 QKTLQEKELTCQALEQRVKELESDLVRErgahrlEVEKLTLKYEKSQSSQQEMdgENKCVEVLEDRPEENSQSHEIQSNV 1929
Cdd:COG1196  219 KEELKELEAELLLLKLRELEAELEELEA------ELEELEAELEELEAELAEL--EAELEELRLELEELELELEEAQAEE 290

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1930 GTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQEldilkreceQEAEEKLKQEQEDLELKHTSTLKQLM 2009
Cdd:COG1196  291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL---------EEELEELEEELEEAEEELEEAEAELA 361

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 2010 REFNTQLAQKEQELERtvQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQ 2089
Cdd:COG1196  362 EAEEALLEAEAELAEA--EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 20127150 2090 TQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYE 2154
Cdd:COG1196  440 EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
PTZ00121 PTZ00121
MAEBL; Provisional
 1440-2156 8.11e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.31  E-value: 8.11e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1440 SKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDV-KATDAREKEEQICLLKEDLDRQNKKFECLKGEME 1518
Cdd:PTZ00121 1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDArKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1519 VRKSKMEKKEcdlETALKTQTAR-VVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVRE 1597
Cdd:PTZ00121 1163 ARKAEEARKA---EDAKKAEAARkAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1598 AE----ETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQkiaAIRKQLLSQM 1673
Cdd:PTZ00121 1240 EEakkaEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE---AKKKAEEAKK 1316

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1674 EEKTQRYAKDTENRLSELSAQLKEREKQvhslEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERL 1753
Cdd:PTZ00121 1317 ADEAKKKAEEAKKKADAAKKKAEEAKKA----AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK 1392

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1754 CMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETG 1833
Cdd:PTZ00121 1393 ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA 1472

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1834 NNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLE 1913
Cdd:PTZ00121 1473 DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1914 dRPEENSQSHEIQSnvgtVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAE-EKLKQ 1992
Cdd:PTZ00121 1553 -KAEELKKAEEKKK----AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKaEELKK 1627

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1993 EQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVE---AELLESHQEETQQLHRKIAEKEDDLRRTA-- 2067
Cdd:PTZ00121 1628 AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDkkkAEEAKKAEEDEKKAAEALKKEAEEAKKAEel 1707

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  2068 -------RRYEEILDAREEEMTGKVTDLQTQLEElQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELR 2140
Cdd:PTZ00121 1708 kkkeaeeKKKAEELKKAEEENKIKAEEAKKEAEE-DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786

                         730
                  ....*....|....*.
gi 20127150  2141 EQVHNLEDRLKRYEKN 2156
Cdd:PTZ00121 1787 EEDEKRRMEVDKKIKD 1802
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1285-1713 2.26e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.67  E-value: 2.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1285 QVSELEAQLTQLTEEQRTLKSSFQQVTNQL---EEKEKQIKTMKADIEGL-------LTEKEALQQEGGQQRQAASEKES 1354
Cdd:PRK02224  214 ELAELDEEIERYEEQREQARETRDEADEVLeehEERREELETLEAEIEDLretiaetEREREELAEEVRDLRERLEELEE 293

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1355 CITQLKKELA---ENINAVTLLREELSEKKSEIA-SLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQ 1430
Cdd:PRK02224  294 ERDDLLAEAGlddADAEAVEARREELEDRDEELRdRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELE 373

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1431 ELSLKVDAlSKEKMSALE-QVDHWSNKFS---EWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLlKEDLDRQ 1506
Cdd:PRK02224  374 EAREAVED-RREEIEELEeEIEELRERFGdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE-AEALLEA 451

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1507 NKKFECLK-----------GEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQrKKEVESLNETLKNYNQQRDTEHS 1575
Cdd:PRK02224  452 GKCPECGQpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRE 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1576 GLVQRLQHLEEL----------GEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNsSVKSRDGELKALEDKLE 1645
Cdd:PRK02224  531 TIEEKRERAEELreraaeleaeAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIE 609

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 20127150  1646 LESAAKVELKRKAEQKiaaiRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1713
Cdd:PRK02224  610 RLREKREALAELNDER----RERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELR 673
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
993-1397 2.40e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.67  E-value: 2.40e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   993 EAKLKKELENTVLELSQKEKQFNAQIlemaqansagisdtvSRLEENQRQQIESLTgahqrKLDDVIEAWEKKLsqqaae 1072
Cdd:PRK02224  197 EEKEEKDLHERLNGLESELAELDEEI---------------ERYEEQREQARETRD-----EADEVLEEHEERR------ 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1073 lrdkhaEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVE 1152
Cdd:PRK02224  251 ------EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1153 KLEADL-------GCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSL------ 1219
Cdd:PRK02224  325 ELRDRLeecrvaaQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdap 404

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1220 ----NLKSLLEELASQLD-----------------SRCERTKALLEA----------KTNELVCT---SRDKADAILARL 1265
Cdd:PRK02224  405 vdlgNAEDFLEELREERDelrereaeleatlrtarERVEEAEALLEAgkcpecgqpvEGSPHVETieeDRERVEELEAEL 484

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1266 SQCQRHTATVgEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQ 1345
Cdd:PRK02224  485 EDLEEEVEEV-EERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEA 563

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 20127150  1346 RQAASEKESCITQLKKELAENINAVTLLR------EELSEKKSEIASLSKQLSDLGAQ 1397
Cdd:PRK02224  564 EEEAEEAREEVAELNSKLAELKERIESLErirtllAAIADAEDEIERLREKREALAEL 621
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2182-2225 4.35e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 51.07  E-value: 4.35e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 20127150    2182 PTEFEYLRKVMFEYMMGRET--KTMAKVITTVLKFPDDQAQKILER 2225
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 853-1668 8.89e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.82  E-value: 8.89e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    853 TEKSLLTKQVVEMETHKKHVceeldaQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQM 932
Cdd:pfam15921   49 TQIPIFPKYEVELDSPRKII------AYPGKEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEM 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    933 REEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLkKELENTVLELSQKEK 1012
Cdd:pfam15921  123 QMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVL-QEIRSILVDFEEASG 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1013 QFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGaHQRKLDDVIEAWEKKLSQQAAELRDKHAEQME----EKEQGL 1088
Cdd:pfam15921  202 KKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKG-RIFPVEDQLEALKSESQNKIELLLQQHQDRIEqlisEHEVEI 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1089 GELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVS-LSERESQLQSQVEKLEADLGCSLSEKLS 1167
Cdd:pfam15921  281 TGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSeLREAKRMYEDKIEELEKQLVLANSELTE 360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1168 LQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckSLHELSKKSLEDKSLNLKSLLEELASQLDSR---CERTKALLE 1244
Cdd:pfam15921  361 ARTERDQFSQESGNLDDQLQKLLADLHKREKEL----SLEKEQNKRLWDRDTGNSITIDHLRRELDDRnmeVQRLEALLK 436

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1245 AKTNELVCTSRDKADAILARLSQCQRHTATVGE-----ALLRRMgqVSELEAQLTQLTEEQRT---LKSSFQQVTNQLEE 1316
Cdd:pfam15921  437 AMKSECQGQMERQMAAIQGKNESLEKVSSLTAQlestkEMLRKV--VEELTAKKMTLESSERTvsdLTASLQEKERAIEA 514

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1317 KEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEScitqLKKELAENINAVTLLREELSEKKSEIASLSKQLSDL-- 1394
Cdd:pfam15921  515 TNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEA----LKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMqv 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1395 -GAQLESSISpsdkaeaisalskqheeqelqlqaQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQS 1473
Cdd:pfam15921  591 eKAQLEKEIN------------------------DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLR 646

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1474 TIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRK 1553
Cdd:pfam15921  647 AVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAM 726

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1554 KEVESLNETLKNYNQQRDtehsGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSS---V 1630
Cdd:pfam15921  727 KVAMGMQKQITAKRGQID----ALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQerrL 802

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 20127150   1631 KSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQ 1668
Cdd:pfam15921  803 KEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQ 840
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1185-1713 2.49e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.02  E-value: 2.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1185 RVSELTGQVQAAEK--ELQSCKSLHELSKKSLEDKSLNLK-SLLEELASQLDSRCERTKALLEAKTNEL------VCTSR 1255
Cdd:COG1196  201 QLEPLERQAEKAERyrELKEELKELEAELLLLKLRELEAElEELEAELEELEAELEELEAELAELEAELeelrleLEELE 280

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1256 DKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKssfqqvtNQLEEKEKQIKTMKADIEGLLTEK 1335
Cdd:COG1196  281 LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE-------EELEELEEELEELEEELEEAEEEL 353

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1336 EALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISpsdKAEAISALS 1415
Cdd:COG1196  354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE---ELEELEEAL 430

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1416 KQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQStiKDLQAQLDVKATDAREKEEQ 1495
Cdd:COG1196  431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLE 508

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1496 ICLLKEDLDRQNKKFECLKGEMEVRKSkmekkecdLETALktQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT--- 1572
Cdd:COG1196  509 GVKAALLLAGLRGLAGAVAVLIGVEAA--------YEAAL--EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflp 578

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1573 ----EHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGEL-KALEDKLELE 1647
Cdd:COG1196  579 ldkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLReVTLEGEGGSA 658

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 20127150 1648 SAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1713
Cdd:COG1196  659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1033-1713 8.76e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.27  E-value: 8.76e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1033 VSRLEENQRQQIESLtgahQRKLDDVIEAWEKK---LSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEV 1109
Cdd:pfam15921   76 IERVLEEYSHQVKDL----QRRLNESNELHEKQkfyLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1110 ARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLR---- 1185
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILReldt 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1186 -VSELTGQVQAAEKELQSCKSlhelskksledkslNLKSLLEELASQLDSRCERTKALLEAKTN---ELVCTSRDKADAI 1261
Cdd:pfam15921  232 eISYLKGRIFPVEDQLEALKS--------------ESQNKIELLLQQHQDRIEQLISEHEVEITgltEKASSARSQANSI 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1262 LARLSQCQRHTATVGEALLRrmgQVSELEAQLTQLTEEQRTLKSSFQqvtNQLEEKEKQIKTMKADIEGLLTEKEALQQE 1341
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMR---QLSDLESTVSQLRSELREAKRMYE---DKIEELEKQLVLANSELTEARTERDQFSQE 371

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1342 GG------QQRQAASEKESCITQLKKELAENI------NAVTL--LREELSEKKSEIASLSKQL----SDLGAQLESSIS 1403
Cdd:pfam15921  372 SGnlddqlQKLLADLHKREKELSLEKEQNKRLwdrdtgNSITIdhLRRELDDRNMEVQRLEALLkamkSECQGQMERQMA 451

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1404 P----SDKAEAISALSKQHEEQELQLQAQLQELSLKVDALS-------------KEKMSALEQVDHWSNKFS---EWKKK 1463
Cdd:pfam15921  452 AiqgkNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLEssertvsdltaslQEKERAIEATNAEITKLRsrvDLKLQ 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1464 AQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNK---KFECLKGEMEVRKSKMEKKECDLETALK---- 1536
Cdd:pfam15921  532 ELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgQHGRTAGAMQVEKAQLEKEINDRRLELQefki 611

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1537 ---TQTARVVELE----DCVTQRKKEVESLNETL---KNYNQQRDTEHSGLVQRLQHLEELGEEKD-------NKVREAE 1599
Cdd:pfam15921  612 lkdKKDAKIRELEarvsDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLSEDYEvlkrnfrNKSEEME 691

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1600 ETVLRLREHVSSLEAELGTVKKELEHVNSS--------------VKSRDGELKALEDKLELESAAKVELKRKaeqkiaai 1665
Cdd:pfam15921  692 TTTNKLKMQLKSAQSELEQTRNTLKSMEGSdghamkvamgmqkqITAKRGQIDALQSKIQFLEEAMTNANKE-------- 763

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 20127150   1666 rKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1713
Cdd:pfam15921  764 -KHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2183-2222 1.81e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 43.50  E-value: 1.81e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 20127150   2183 TEFEYLRKVMFEYMMGRET---KTMAKVITTVLKFPDDQAQKI 2222
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1476-2155 1.01e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.58  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1476 KDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV--RKSKMEKKECDLETALKTQTARVVELEDCVTQRK 1553
Cdd:pfam02463  233 KLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEeeKEKKLQEEELKLLAKEEEELKSELLKLERRKVDD 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1554 KEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSR 1633
Cdd:pfam02463  313 EEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1634 DGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQmEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1713
Cdd:pfam02463  393 KEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEI-LEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1714 SSPHPEVPAVSRSMQSVAASPEQEAPDSQDCThkACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKL 1793
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKES--KARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAV 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1794 DCTRAR-QLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELES 1872
Cdd:pfam02463  550 IVEVSAtADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGIL 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1873 DLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK 1952
Cdd:pfam02463  630 KDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREK 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1953 LSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNtqlaQKEQELERTVQETID 2032
Cdd:pfam02463  710 EELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELS----LKEKELAEEREKTEK 785

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   2033 KAQEVEAELLESHQEETqqlhrkIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDS 2112
Cdd:pfam02463  786 LKVEEEKEEKLKAQEEE------LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERL 859

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|...
gi 20127150   2113 VTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEK 2155
Cdd:pfam02463  860 EEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKEL 902
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 602-846 2.12e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 43.67  E-value: 2.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   602 ESKTQSEHLAVHLE---AEKNKHNKELTALAEQHRTEVEGlQQQQDSLWTERLQSLSQQHQAaveeLREKYQQEKDALLK 678
Cdd:NF012221 1539 ESSQQADAVSKHAKqddAAQNALADKERAEADRQRLEQEK-QQQLAAISGSQSQLESTDQNA----LETNGQAQRDAILE 1613

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   679 EKESlFQAHIQDMNeKTLEKLDkkqmELESVSSELSEalRARDQLAEE-LSVLRGDADKMKQALEAELEEQRRHH---QR 754
Cdd:NF012221 1614 ESRA-VTKELTTLA-QGLDALD----SQATYAGESGD--QWRNPFAGGlLDRVQEQLDDAKKISGKQLADAKQRHvdnQQ 1685

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   755 EVGSISEQQELTVRRAEKalkdelSRLGALLDERDEHlreRQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQA 834
Cdd:NF012221 1686 KVKDAVAKSEAGVAQGEQ------NQANAEQDIDDAK---ADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS 1756

                         250
                  ....*....|..
gi 20127150   835 GAyEEQLAQMQQ 846
Cdd:NF012221 1757 AA-ENKANQAQA 1767
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 157-552 3.41e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.80  E-value: 3.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    157 REQLLQRLRRMERSLSSY-RGKYSELVTAFQTLQREKKKLQGILSQ--SQDKSLRRISELREELQMDQQAKKHLQDEFDA 233
Cdd:pfam15921  424 RNMEVQRLEALLKAMKSEcQGQMERQMAAIQGKNESLEKVSSLTAQleSTKEMLRKVVEELTAKKMTLESSERTVSDLTA 503

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    234 CLEEKDQYISVLQTQVSLLKQRLQNGPMNVDAPKPlpPGELQAEVHGDTEKMEGVGEPVGggtsaKTLEMLQQRVkrqEN 313
Cdd:pfam15921  504 SLQEKERAIEATNAEITKLRSRVDLKLQELQHLKN--EGDHLRNVQTECEALKLQMAEKD-----KVIEILRQQI---EN 573

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    314 LLQrckeTIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELH-----------------MAEKTKLITQLRDAKNLIE 376
Cdd:pfam15921  574 MTQ----LVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKdkkdakirelearvsdlELEKVKLVNAGSERLRAVK 649

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    377 QLEQDKGMVITETKRQMLETLELKED-EIAQ--LRSHIKQMTTQGEELREQKeKSERAAFEELEKALSTAQKTEDAQRRM 453
Cdd:pfam15921  650 DIKQERDQLLNEVKTSRNELNSLSEDyEVLKrnFRNKSEEMETTTNKLKMQL-KSAQSELEQTRNTLKSMEGSDGHAMKV 728

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    454 KMEMDEQMKAVERASEEERLRLQhelsrVRQEAASMAKKNSEEQVAALQKLHAE--ELASKEQELSRRLE---ARERELQ 528
Cdd:pfam15921  729 AMGMQKQITAKRGQIDALQSKIQ-----FLEEAMTNANKEKHFLKEEKNKLSQElsTVATEKNKMAGELEvlrSQERRLK 803

                          410       420       430
                   ....*....|....*....|....*....|
gi 20127150    529 EQ---MRIALEKSRSEYLK---LTQEKEQQ 552
Cdd:pfam15921  804 EKvanMEVALDKASLQFAEcqdIIQRQEQE 833
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 296-502 6.57e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 6.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  296 TSAKTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMK----ELHMAEKTKLITQLRDA 371
Cdd:COG4942   52 ALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLralyRLGRQPPLALLLSPEDF 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  372 KNLIEQLEQDKGmvITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERaafeELEKALSTAQKTEDAQR 451
Cdd:COG4942  132 LDAVRRLQYLKY--LAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERA----ALEALKAERQKLLARLE 205

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 20127150  452 RMKMEMDEQMKAVERASEeerlRLQHELSRVRQEAASMAKKNSEEQVAALQ 502
Cdd:COG4942  206 KELAELAAELAELQQEAE----ELEALIARLEAEAAAAAERTPAAGFAALK 252
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1933-2043 7.78e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 40.77  E-value: 7.78e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    1933 DGLRSDLESKLTGAERDKQKLSKE-------VARLQKELRALRREHQQeLDILKRECEQEAEEKLKQEQEDLElkhtSTL 2005
Cdd:smart00787  143 EGLKEGLDENLEGLKEDYKLLMKElellnsiKPKLRDRKDALEEELRQ-LKQLEDELEDCDPTELDRAKEKLK----KLL 217

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|
gi 20127150    2006 KQLMREFN--TQLAQKEQELERTVQETIDKAQEVEAELLE 2043
Cdd:smart00787  218 QEIMIKVKklEELEEELQELESKIEDLTNKKSELNTEIAE 257
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 401-982 7.12e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.86  E-value: 7.12e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  401 EDEIAQLRSHIKQMTTQGE------ELREQKEKSE-RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV-ERASEEER 472
Cdd:COG1196  192 EDILGELERQLEPLERQAEkaeryrELKEELKELEaELLLLKLRELEAELEELEAELEELEAELEELEAELaELEAELEE 271

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  473 LRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQ 552
Cdd:COG1196  272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  553 ESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKHNKELTALAEQH 632
Cdd:COG1196  352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE-ALLERLERLEEELEELEEAL 430

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  633 RTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDK---KQMELESV 709
Cdd:COG1196  431 AELEEEEEEEEEAL--EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLeaeADYEGFLE 508

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  710 SSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQ--QELTVRRAEKALKDELSRLGALLDE 787
Cdd:COG1196  509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRARAAL 588

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  788 RDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTkqvvEMET 867
Cdd:COG1196  589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG----SLTG 664

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  868 HKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTL 947
Cdd:COG1196  665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                        570       580       590
                 ....*....|....*....|....*....|....*
gi 20127150  948 SSKEESISILHEEYETKFKNQEKRMEKIKQKAKEM 982
Cdd:COG1196  745 EELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 693-1299 2.99e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.39  E-value: 2.99e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  693 EKTLEKLDKKQMELESVSSELSEalrardqLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEL--TVRRA 770
Cdd:COG1196  175 EEAERKLEATEENLERLEDILGE-------LERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAE 247

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  771 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLD 850
Cdd:COG1196  248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  851 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENIIL 930
Cdd:COG1196  328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELE 406

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  931 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK-KELENTVLELSQ 1009
Cdd:COG1196  407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAlLEAALAELLEEL 486

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1010 KEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQR----KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKE 1085
Cdd:COG1196  487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1086 QGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQsqvekleADLGCSLSEK 1165
Cdd:COG1196  567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRA 639

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1166 LSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEA 1245
Cdd:COG1196  640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                        570       580       590       600       610
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 20127150 1246 KTNELV--CTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEE 1299
Cdd:COG1196  720 ELEEEAleEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 693-1399 7.22e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 94.36  E-value: 7.22e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    693 EKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRGDADKMkQALEAELEEQRRHHQREVGSISEQQELTVRRAEK 772
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRRE----REKAERY-QALLKEKREYEGYELLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    773 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQAL-AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL 851
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVkEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    852 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQ----RSELEEKVRSLAQLQDsQLKNSTVEKEQA---RQSLME 924
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEledlRAELEEVDKEFAETRD-ELKDYREKLEKLkreINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    925 KENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEA---KLKKELE 1001
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEeydRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1002 NTVLELSQKEKQ---------FNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAE 1072
Cdd:TIGR02169  487 KLQRELAEAEAQaraseervrGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIEL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1073 LRDKHA--------EQMEEKEQGLGELRQK------VRIVQSEKEELTKEVARLKEAVSGQDVALA----------GLQG 1128
Cdd:TIGR02169  567 LKRRKAgratflplNKMRDERRDLSILSEDgvigfaVDLVEFDPKYEPAFKYVFGDTLVVEDIEAArrlmgkyrmvTLEG 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1129 QLEQKSAVIVSLSERESQLQS-------QVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQ 1201
Cdd:TIGR02169  647 ELFEKSGAMTGGSRAPRGGILfsrsepaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1202 SCKSLHELSK----------KSLEDKSLNLKSLLEELASQLDSRcERTKALLEAKTNELvctsrdKADAILARLSQCQRH 1271
Cdd:TIGR02169  727 QLEQEEEKLKerleeleedlSSLEQEIENVKSELKELEARIEEL-EEDLHKLEEALNDL------EARLSHSRIPEIQAE 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1272 TATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASE 1351
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRD 879

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 20127150   1352 KESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLE 1399
Cdd:TIGR02169  880 LESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 456-1048 4.36e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.54  E-value: 4.36e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  456 EMDEQMKAVERASE--EERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLhAEELASKEQELSRRLEARERELQE---- 529
Cdd:COG1196  197 ELERQLEPLERQAEkaERYRELKEELKELEAELLLLKLRELEAELEELEAE-LEELEAELEELEAELAELEAELEElrle 275

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  530 --QMRIALEKSRSEYLKLTQEKEQ--QESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKT 605
Cdd:COG1196  276 leELELELEEAQAEEYELLAELARleQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE 355

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  606 QSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLfq 685
Cdd:COG1196  356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL-- 433

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  686 ahiqdmnektLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRgdadkmkqALEAELEEQRRHHQREVGSISEQQEL 765
Cdd:COG1196  434 ----------EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL--------EEAALLEAALAELLEELAEAAARLLL 495

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  766 TVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQ 845
Cdd:COG1196  496 LLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT 575

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  846 QKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEK 925
Cdd:COG1196  576 FLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEG 655

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  926 ENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVL 1005
Cdd:COG1196  656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE 735

                        570       580       590       600
                 ....*....|....*....|....*....|....*....|...
gi 20127150 1006 ELSQKEKQFNAQILEMAQANSAGISDtvsrlEENQRQQIESLT 1048
Cdd:COG1196  736 ELLEELLEEEELLEEEALEELPEPPD-----LEELERELERLE 773
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 337-991 5.21e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.15  E-value: 5.21e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  337 EALQEQLDERLQELEKMKElhmaektklitQLRDAKNLIEQLEQDKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTT 416
Cdd:COG1196  192 EDILGELERQLEPLERQAE-----------KAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEA 260

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  417 QGEELREQKEKsERAAFEELEKALSTAQKTE------------DAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQ 484
Cdd:COG1196  261 ELAELEAELEE-LRLELEELELELEEAQAEEyellaelarleqDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  485 EAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEqmrialeksrseylkltQEKEQQESLALEELELQK 564
Cdd:COG1196  340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL-----------------AEELLEALRAAAELAAQL 402

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  565 KAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEhlAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQD 644
Cdd:COG1196  403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE--AAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  645 SLwterlqSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLA 724
Cdd:COG1196  481 EL------LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE 554

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  725 EELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEA 804
Cdd:COG1196  555 DDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  805 HLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQ 884
Cdd:COG1196  635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  885 QLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQmREEQAKEIEILKQTLSSKEE----SIsilhEE 960
Cdd:COG1196  715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD-LEELERELERLEREIEALGPvnllAI----EE 789

                        650       660       670
                 ....*....|....*....|....*....|.
gi 20127150  961 YETkfknQEKRMEKIKQKAKEMQETKKKLLD 991
Cdd:COG1196  790 YEE----LEERYDFLSEQREDLEEARETLEE 816
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 570-1407 5.25e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 5.25e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    570 ESENKLQElgqeAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALA---EQHRTEVEGLQQQQDSL 646
Cdd:TIGR02168  176 ETERKLER----TRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVlrlEELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    647 WTER--LQSLSQQHQAAVEELReKYQQEKDALLKEKESLFQAHIQDMNEKTL------EKLDKKQMELESVSSELSEALR 718
Cdd:TIGR02168  252 EEELeeLTAELQELEEKLEELR-LEVSELEEEIEELQKELYALANEISRLEQqkqilrERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    719 ARDQLAEELsvlrgdadkmkQALEAELEEQRRHHQREVGSISEQQELTV--RRAEKALKDELSRLGALLDERDEHLRERQ 796
Cdd:TIGR02168  331 KLDELAEEL-----------AELEEKLEELKEELESLEAELEELEAELEelESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    797 ARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAR-----EQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKH 871
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkelqAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    872 VCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNS----------TVEKEQARQ---SLMEKENIILQMREEQAK 938
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSgilgvlseliSVDEGYEAAieaALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    939 E-IEILKQTLSSKE---ESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL----------------LDQEAKLKK 998
Cdd:TIGR02168  560 KaIAFLKQNELGRVtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggvlvvddLDNALELAK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    999 ELENTVLELSQKEKQFNAQILeMAQANSAGISDTVSRLEE--NQRQQIESLTGAhQRKLDDVIEAWEKKLSQQAAELRDK 1076
Cdd:TIGR02168  640 KLRPGYRIVTLDGDLVRPGGV-ITGGSAKTNSSILERRREieELEEKIEELEEK-IAELEKALAELRKELEELEEELEQL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1077 HAEqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEA 1156
Cdd:TIGR02168  718 RKE-LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1157 DLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckslhELSKKSLEDKSLNLKSLLEELASqldsrc 1236
Cdd:TIGR02168  797 ELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL-------EDLEEQIEELSEDIESLAAEIEE------ 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1237 ertkalLEAKTNELvctsRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEE 1316
Cdd:TIGR02168  864 ------LEELIEEL----ESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1317 KEKQIKTMKADI--EGLLTEKEALQQEGGQQRQAASEKEScITQLKKELAE----NINAVtllrEELSEKKSEIASLSKQ 1390
Cdd:TIGR02168  934 LEVRIDNLQERLseEYSLTLEEAEALENKIEDDEEEARRR-LKRLENKIKElgpvNLAAI----EEYEELKERYDFLTAQ 1008

                          890       900
                   ....*....|....*....|
gi 20127150   1391 LSDLG---AQLESSISPSDK 1407
Cdd:TIGR02168 1009 KEDLTeakETLEEAIEEIDR 1028
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 388-1176 3.46e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 3.46e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    388 ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSER-----AAFEELEKALSTAQKTEDAQRRMKMEMDEQMK 462
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERykelkAELRELELALLVLRLEELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    463 AVERASEEERLR-LQHELSRVRQEAASMakknsEEQVAALQKlhaeELASKEQELSrRLEARERELQEQMRIALEKsrSE 541
Cdd:TIGR02168  252 EEELEELTAELQeLEEKLEELRLEVSEL-----EEEIEELQK----ELYALANEIS-RLEQQKQILRERLANLERQ--LE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    542 YLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKH 621
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA-QLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    622 NKELTALaeqhRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALlkekeslfqahiqdmnEKTLEKLDK 701
Cdd:TIGR02168  399 NNEIERL----EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL----------------EELQEELER 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    702 KQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRR-----HHQRE----VGSISEQ---------- 762
Cdd:TIGR02168  459 LEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGvkallKNQSGlsgiLGVLSELisvdegyeaa 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    763 ---------QELTVRRAEKALKD---------------ELSRL-GALLDERDEHLRERQARVQDLEAHLQKSAGE----- 812
Cdd:TIGR02168  539 ieaalggrlQAVVVENLNAAKKAiaflkqnelgrvtflPLDSIkGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    813 ------------LQQALAKLDLLHSEQSAAREQA------GAYEEQLAQMQQKVLDLETEKSLLTKQVVEMEthkkhvcE 874
Cdd:TIGR02168  619 syllggvlvvddLDNALELAKKLRPGYRIVTLDGdlvrpgGVITGGSAKTNSSILERRREIEELEEKIEELE-------E 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    875 ELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENiILQMREEQAKEIEILKQTLSSKEESI 954
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ-LEERIAQLSKELTELEAEIEELEERL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    955 silhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEkqfnaQILEMAQANSAGISDTVS 1034
Cdd:TIGR02168  771 ----EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR-----ERLESLERRIAATERRLE 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1035 RLE---ENQRQQIESLTGAhQRKLDDVIEAWEKKLsQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVAR 1111
Cdd:TIGR02168  842 DLEeqiEELSEDIESLAAE-IEELEELIEELESEL-EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 20127150   1112 LKEAVSGQDVALAGLQGQLEQksaVIVSLSERESQLQSQVEKLEADLGCSLSEklsLQEELAELK 1176
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDN---LQERLSEEYSLTLEEAEALENKIEDDEEE---ARRRLKRLE 978
PTZ00121 PTZ00121
MAEBL; Provisional
 335-1064 2.86e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 85.96  E-value: 2.86e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   335 EKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAknlieqlEQDKGMVITETKRQMLETLELKEDEIAQLRSHIKQM 414
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKA 1184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   415 --TTQGEELR--EQKEKSERAAFEELEKALSTAQKTEDAQRRMKM-EMDEQMKAVERASEEERLRLQHELsRVRQEAASM 489
Cdd:PTZ00121 1185 eeVRKAEELRkaEDARKAEAARKAEEERKAEEARKAEDAKKAEAVkKAEEAKKDAEEAKKAEEERNNEEI-RKFEEARMA 1263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   490 AKKNSEEQVAALQKLHAEELaSKEQELSRRLEARE----RELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKK 565
Cdd:PTZ00121 1264 HFARRQAAIKAEEARKADEL-KKAEEKKKADEAKKaeekKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAK 1342

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   566 AILTESENKLQELGQEAEAYRtrilELETSLEKSLQESKTQSEhlAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDS 645
Cdd:PTZ00121 1343 KAAEAAKAEAEAAADEAEAAE----EKAEAAEKKKEEAKKKAD--AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA 1416

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   646 LWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLD----KKQMELESVSSELSEALRARD 721
Cdd:PTZ00121 1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKadeaKKKAEEAKKADEAKKKAEEAK 1496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   722 QLAEElsvLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARvqd 801
Cdd:PTZ00121 1497 KKADE---AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK--- 1570

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   802 leahlqKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRA 881
Cdd:PTZ00121 1571 ------KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE 1644

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   882 QVQQLERQRSELEE-KVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEesisilhEE 960
Cdd:PTZ00121 1645 EKKKAEELKKAEEEnKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK-------KK 1717

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   961 YETKFKNQEKRMEKIKQKAKEMQETKKKLldQEAKLKKELENTVLELSQKEKQfnaQILEMAQANSAGISDTVSRLEENQ 1040
Cdd:PTZ00121 1718 AEELKKAEEENKIKAEEAKKEAEEDKKKA--EEAKKDEEEKKKIAHLKKEEEK---KAEEIRKEKEAVIEEELDEEDEKR 1792

                         730       740
                  ....*....|....*....|....
gi 20127150  1041 RQQIESLTGAHQRKLDDVIEAWEK 1064
Cdd:PTZ00121 1793 RMEVDKKIKDIFDNFANIIEGGKE 1816
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 299-900 3.37e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.37  E-value: 3.37e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  299 KTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQL 378
Cdd:COG1196  239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERL 318

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  379 EQdkgmvITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRmkmEMD 458
Cdd:COG1196  319 EE-----LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE---LLE 390

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  459 EQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIAleks 538
Cdd:COG1196  391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA---- 466

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  539 rseylklTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLqesktQSEHLAVHLEAEK 618
Cdd:COG1196  467 -------ELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG-----LAGAVAVLIGVEA 534

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  619 NKHNKELTALAEQHRTEVEglqqQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEK 698
Cdd:COG1196  535 AYEAALEAALAAALQNIVV----EDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  699 LDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELE--EQRRHHQREVGSISEQQELTVRRAEKALKD 776
Cdd:COG1196  611 ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAggSLTGGSRRELLAALLEAEAELEELAERLAE 690

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  777 ELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKS 856
Cdd:COG1196  691 EELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770

                        570       580       590       600
                 ....*....|....*....|....*....|....*....|....*...
gi 20127150  857 LLTKQVVEMEThkkhV----CEELDAQRAQVQQLERQRSELEEKVRSL 900
Cdd:COG1196  771 RLEREIEALGP----VnllaIEEYEELEERYDFLSEQREDLEEARETL 814
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 761-1707 4.99e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 4.99e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    761 EQQELTVRRAEKALKDeLSRLGALLDERDEHLR--ERQARVQDLEAHLQKSAGELQQALAKLDLLhseqsAAREQAGAYE 838
Cdd:TIGR02168  172 ERRKETERKLERTREN-LDRLEDILNELERQLKslERQAEKAERYKELKAELRELELALLVLRLE-----ELREELEELQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    839 EQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQlQDSQLKNSTVEKEQA 918
Cdd:TIGR02168  246 EELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE-RLANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    919 RQSLMEKENIILQMREEQAKEIEILKQTLsskeESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKK 998
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEEL----ESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    999 ELENTVLELSQKEkqfnaqilEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKkLSQQAAELRdkha 1078
Cdd:TIGR02168  401 EIERLEARLERLE--------DRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELER-LEEALEELR---- 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1079 EQMEEKEQGLGELRQKVRIVQSEKEELtkevARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSER---ESQLQSQVEK-L 1154
Cdd:TIGR02168  468 EELEEAEQALDAAERELAQLQARLDSL----ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvDEGYEAAIEAaL 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1155 EADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTG----QVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAS 1230
Cdd:TIGR02168  544 GGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLG 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1231 QLdsrcertkalleaktneLVCTSRDKADAILARLSQCQRHTATVGEaLLRRMGQVSELEAQLTQLTEEQRtlkssfqqv 1310
Cdd:TIGR02168  624 GV-----------------LVVDDLDNALELAKKLRPGYRIVTLDGD-LVRPGGVITGGSAKTNSSILERR--------- 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1311 tNQLEEKEKQIKTMKADIEGLLTEKEALqqeggqqRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQ 1390
Cdd:TIGR02168  677 -REIEELEEKIEELEEKIAELEKALAEL-------RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1391 LSDLGAQLEssispsdKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQ 1470
Cdd:TIGR02168  749 IAQLSKELT-------ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN 821

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1471 HQSTIKDLQAQLDVKATDAREKEEQICLLKEDLdrqnkkfECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEdcvt 1550
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDI-------ESLAAEIEELEELIEELESELEALLNERASLEEALA---- 890

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1551 QRKKEVESLNETLKNYNQQRDTehsgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLeaelgtVKKELEHVNSSV 1630
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRSE----LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE------YSLTLEEAEALE 960

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 20127150   1631 KSRDGELKALEDKLelesaakvelkRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLED 1707
Cdd:TIGR02168  961 NKIEDDEEEARRRL-----------KRLENKIKELGPVNLAAIEE-----YEELKERYDFLTAQKEDLTEAKETLEE 1021
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 880-1712 2.03e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 2.03e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    880 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQaKEIEILKQTLSSKEESISILHE 959
Cdd:TIGR02168  199 ERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEEL-EELTAELQELEEKLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    960 EYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQansagisdtvsrleen 1039
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAE---------------- 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1040 QRQQIESLTGAHQRKLDDVIEAWEKklsQQAAELRdkhaeqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQ 1119
Cdd:TIGR02168  342 LEEKLEELKEELESLEAELEELEAE---LEELESR------LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1120 DVALAGLQGQLEQKSAVIVSLSEREsqLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKE 1199
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1200 LQSCKSLHEL------SKKSLEDKSLNLKSLLEELASQLDSRCERTKAL---LEAKTNELVCTSRDKADAILARLSQCQR 1270
Cdd:TIGR02168  491 LDSLERLQENlegfseGVKALLKNQSGLSGILGVLSELISVDEGYEAAIeaaLGGRLQAVVVENLNAAKKAIAFLKQNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1271 HTATVGEALLRRmgqvselEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQ--- 1347
Cdd:TIGR02168  571 GRVTFLPLDSIK-------GTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKlrp 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1348 --------------------AASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDK 1407
Cdd:TIGR02168  644 gyrivtldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1408 AEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKAT 1487
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1488 DAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYN 1567
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1568 QQRdtehsglvQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgelkaledklele 1647
Cdd:TIGR02168  884 SLE--------EALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE----------------------- 932

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 20127150   1648 saakvelkrKAEQKIAairkQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNL 1712
Cdd:TIGR02168  933 ---------GLEVRID----NLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 164-1010 6.40e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.26  E-value: 6.40e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    164 LRRMERSLSSYRgKYSELVTAFQTLQREKKKLQGILS----QSQDKSLRRISELREELQMDQQAKKHLQDEFDACLEEKD 239
Cdd:TIGR02168  195 LNELERQLKSLE-RQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    240 QYISVLQTQVSLLKQRLQNgpmnvdapkplppgeLQAEVHG-DTEKMEGVGEPVGGGTSAKTLEMLQQRVKRQENLLQRC 318
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYA---------------LANEISRlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    319 KETIgshKEQCALLLSEKEALQEQLDERLQELEKMKElHMAEKTKLITQLRDAKNLIEQLEQdkgmVITETKRQMLETLE 398
Cdd:TIGR02168  339 LAEL---EEKLEELKEELESLEAELEELEAELEELES-RLEELEEQLETLRSKVAQLELQIA----SLNNEIERLEARLE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    399 LKEDEIAQLRSHIKQmttQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHE 478
Cdd:TIGR02168  411 RLEDRRERLQQEIEE---LLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    479 LSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARErELQEQMRIALEKSRSEYLKLTQEKEQQESLALE 558
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDE-GYEAAIEAALGGRLQAVVVENLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    559 ELELQKKAIL-------TESENKLQELGQEAEAYRTRILELETSLEK----------------SLQE-----SKTQSEHL 610
Cdd:TIGR02168  567 QNELGRVTFLpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvvdDLDNalelaKKLRPGYR 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    611 AVHLEAEK-------NKHNKELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESL 683
Cdd:TIGR02168  647 IVTLDGDLvrpggviTGGSAKTNSSILERRREIEELEEKIEEL-EEKIAELEKALAELRKELEELEEELEQLRKELEELS 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    684 FQAHIQDMNEKTLEKldkkqmELESVSSELSEALRARDQLAEELSVLRGDADKMKQALeAELEEQRRHHQREVGSISEQQ 763
Cdd:TIGR02168  726 RQISALRKDLARLEA------EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL-AEAEAEIEELEAQIEQLKEEL 798

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    764 ElTVRRAEKALKDELSRLGALLDErdehLRERQARVQDLEAHLQKSAGELQQALAKLdllhseqsaaREQAGAYEEQLAQ 843
Cdd:TIGR02168  799 K-ALREALDELRAELTLLNEEAAN----LRERLESLERRIAATERRLEDLEEQIEEL----------SEDIESLAAEIEE 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    844 MQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNS--TVEKEQARQ 920
Cdd:TIGR02168  864 LEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELrEKLAQLELRLEglEVRIDNLQE 943

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    921 SLMEKENIILQMREEQAKEIEI----LKQTLSSKEESISILHE---EYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQE 993
Cdd:TIGR02168  944 RLSEEYSLTLEEAEALENKIEDdeeeARRRLKRLENKIKELGPvnlAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAI 1023

                          890
                   ....*....|....*..
gi 20127150    994 AKLKKELENTVLELSQK 1010
Cdd:TIGR02168 1024 EEIDREARERFKDTFDQ 1040
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 300-870 1.44e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.98  E-value: 1.44e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  300 TLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLE 379
Cdd:COG1196  275 ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  380 QdkgmvitetKRQMLETLELKEDEIAQLRshikqmttqgEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDE 459
Cdd:COG1196  355 E---------AEAELAEAEEALLEAEAEL----------AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER 415

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  460 QmkaveRASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSR 539
Cdd:COG1196  416 L-----ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  540 SEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKN 619
Cdd:COG1196  491 ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAK 570

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  620 KHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKL 699
Cdd:COG1196  571 AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  700 -------DKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVgsISEQQELTVRRAEK 772
Cdd:COG1196  651 legeggsAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE--ERLEEELEEEALEE 728

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  773 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLE 852
Cdd:COG1196  729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPVNLLAIEEYEELEERYDFLSEQREDLE 808

                        570
                 ....*....|....*...
gi 20127150  853 TEKSLLTKQVVEMETHKK 870
Cdd:COG1196  809 EARETLEEAIEEIDRETR 826
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 301-1117 2.31e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 2.31e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    301 LEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDE-RLQELEKMKELHMAEKTklitqLRDAKNLIEQLE 379
Cdd:TIGR02168  227 LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEElRLEVSELEEEIEELQKE-----LYALANEISRLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    380 QDKgMVITETKRQMLETLELKEDEIAQLRSHIKQmttQGEELREQKEKSERAA--FEELEKALSTAQKTEdaqrrmkmem 457
Cdd:TIGR02168  302 QQK-QILRERLANLERQLEELEAQLEELESKLDE---LAEELAELEEKLEELKeeLESLEAELEELEAEL---------- 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    458 dEQMKAVERASEEERLRLQHELSRVRQEAASMAKK--NSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQmrial 535
Cdd:TIGR02168  368 -EELESRLEELEEQLETLRSKVAQLELQIASLNNEieRLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAE----- 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    536 eksrSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEhlavhLE 615
Cdd:TIGR02168  442 ----LEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKA-----LL 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    616 AEKNKHNKELTALAEQHRTEvEGLQQQQDSLWTERLQSLsqqhqaaVEELREKYQQEKDALlkEKESLFQAHIQDMNEKT 695
Cdd:TIGR02168  513 KNQSGLSGILGVLSELISVD-EGYEAAIEAALGGRLQAV-------VVENLNAAKKAIAFL--KQNELGRVTFLPLDSIK 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    696 LEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGD-------ADKMKQALEaeleeQRRHHQREVGSISEQQELTVR 768
Cdd:TIGR02168  583 GTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYllggvlvVDDLDNALE-----LAKKLRPGYRIVTLDGDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    769 RAEKALKDELSRLGALldERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKV 848
Cdd:TIGR02168  658 GGVITGGSAKTNSSIL--ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDL 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    849 LDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQAR--------- 919
Cdd:TIGR02168  736 ARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDelraeltll 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    920 ----QSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYEtkfkNQEKRMEKIKQKAKEMQETKKKLLDQEAK 995
Cdd:TIGR02168  816 neeaANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALAL 891

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    996 LKKELENTVLELSQKEKQFNA--QILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQaAEL 1073
Cdd:TIGR02168  892 LRSELEELSEELRELESKRSElrRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDE-EEA 970

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 20127150   1074 RDKhAEQMEEKEQGLG-----------ELRQKVRIVQSEKEELTKEVARLKEAVS 1117
Cdd:TIGR02168  971 RRR-LKRLENKIKELGpvnlaaieeyeELKERYDFLTAQKEDLTEAKETLEEAIE 1024
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 575-1215 8.03e-14

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 77.47  E-value: 8.03e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    575 LQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvhleaekNKHNKELTALAEQHRTEVEGLQQQQDSLWTERlQSL 654
Cdd:pfam15921  226 LRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLL-------QQHQDRIEQLISEHEVEITGLTEKASSARSQA-NSI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    655 SQQHQAAVEELREKYQQEKDAL--LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRG 732
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMRQLsdLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQE----SG 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    733 DADKMKQALEAELeeqrrhHQREvgsiseqQELTVRRAE-KALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAG 811
Cdd:pfam15921  374 NLDDQLQKLLADL------HKRE-------KELSLEKEQnKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKS 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    812 ELQqalakldllhseqsaareqaGAYEEQLAQMQQKVLDLETEKSLlTKQVVEMETHKKHVCEELDAQRAQVQQLERQRS 891
Cdd:pfam15921  441 ECQ--------------------GQMERQMAAIQGKNESLEKVSSL-TAQLESTKEMLRKVVEELTAKKMTLESSERTVS 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    892 EL----EEKVRSLaqlqdsQLKNSTVEKEQARQSLMEKENIILQMREEQAK----EIEILKQTLSSKEESISILHEEyet 963
Cdd:pfam15921  500 DLtaslQEKERAI------EATNAEITKLRSRVDLKLQELQHLKNEGDHLRnvqtECEALKLQMAEKDKVIEILRQQ--- 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    964 kfknqekrMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQ----------KEKQFNAQI--LEMAQANSAGISD 1031
Cdd:pfam15921  571 --------IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkkdaKIRELEARVsdLELEKVKLVNAGS 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1032 TVSRLEENQRQQIESLTGAHQRKLDDVieaweKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEElTKEVAR 1111
Cdd:pfam15921  643 ERLRAVKDIKQERDQLLNEVKTSRNEL-----NSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQ-TRNTLK 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1112 LKEAVSGQDVALA-GLQGQLEQKSAVIVSL----------------------------SERESQLQSQVEKLEADLGCSL 1162
Cdd:pfam15921  717 SMEGSDGHAMKVAmGMQKQITAKRGQIDALqskiqfleeamtnankekhflkeeknklSQELSTVATEKNKMAGELEVLR 796

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 20127150   1163 SEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLE 1215
Cdd:pfam15921  797 SQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 388-1216 1.29e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.03  E-value: 1.29e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    388 ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSER----------AAFEELEKALSTAQKTEDAQRRMKMEM 457
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERyqallkekreYEGYELLKEKEALERQKEAIERQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    458 DEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHA-----EELASKEQELSRRLEARERELQE-QM 531
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGEleaeiASLERSIAEKERELEDAEERLAKlEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    532 RIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKsLQESKTQSEHLA 611
Cdd:TIGR02169  330 EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK-LKREINELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    612 VHLEAEKnkhnKELTALAEQHRTEVEGLQQQQDSLWTERLQSlsqqhQAAVEELREKYQQEKDALLKEKESLFQahiqdm 691
Cdd:TIGR02169  409 DRLQEEL----QRLSEELADLNAAIAGIEAKINELEEEKEDK-----ALEIKKQEWKLEQLAADLSKYEQELYD------ 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    692 nekTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRgdadkmkqALEAELEEQRR--HHQ-REVGSISEQQELTVR 768
Cdd:TIGR02169  474 ---LKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGR--------AVEEVLKASIQgvHGTvAQLGSVGERYATAIE 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    769 RAEKAlkdelsRLGALLDERD-------EHLRERQA-----------RVQDLEAHLQKSAGELQQALAKLD--------- 821
Cdd:TIGR02169  543 VAAGN------RLNNVVVEDDavakeaiELLKRRKAgratflplnkmRDERRDLSILSEDGVIGFAVDLVEfdpkyepaf 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    822 -------LLHSEQSAAREQAGAYeeQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELE 894
Cdd:TIGR02169  617 kyvfgdtLVVEDIEAARRLMGKY--RMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQ 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    895 EKVRSLAQLQDSqlknSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQtlssKEESISILHEEYEtkfkNQEKRMEK 974
Cdd:TIGR02169  695 SELRRIENRLDE----LSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEE----LEEDLSSLEQEIE----NVKSELKE 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    975 IKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFnaqILEMAQANSAGISDTVSRLEENQrQQIESLTGAHQRK 1054
Cdd:TIGR02169  763 LEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSK---LEEEVSRIEARLREIEQKLNRLT-LEKEYLEKEIQEL 838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1055 LDDVIEAWEKKLSQQAAELRDKhaEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKS 1134
Cdd:TIGR02169  839 QEQRIDLKEQIKSIEKEIENLN--GKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1135 AVIVSLSERESQLQSQVEKLEADLGCSLSE----------KLSLQEELAELKLLADKSQLRVSELTgQVQAAEKELQSCK 1204
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEIEDPKGEDEEIpeeelsledvQAELQRVEEEIRALEPVNMLAIQEYE-EVLKRLDELKEKR 995

                          890
                   ....*....|..
gi 20127150   1205 SLHELSKKSLED 1216
Cdd:TIGR02169  996 AKLEEERKAILE 1007
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1019-1713 3.91e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.48  E-value: 3.91e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1019 LEMAQANSAGISDTVSRLEEN-QRQQIESLTGAHQRKLDDVIEAWEKKLS----QQAAELRDKHAEQMEEKEQGLGELRQ 1093
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlKSLERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1094 KVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELA 1173
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1174 ELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAsQLDSRCERTKALLEAKTNELVCT 1253
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1254 SRDKADAI----LARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1329
Cdd:TIGR02168  420 QQEIEELLkkleEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1330 GLLTEKEALQQEGGQQRQAASEKESCITQLKKE----------LAENINAVtlLREELSEKKSEIASLSKQLSDLGAQLE 1399
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1400 SSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDAL----------SKEKMSALEQV--------------DHWSN 1455
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvVDDLDNALELAkklrpgyrivtldgDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1456 KFSEWK----------------KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV 1519
Cdd:TIGR02168  658 GGVITGgsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1520 RKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT---EHSGLVQRLQHLEE 1586
Cdd:TIGR02168  738 LEAEVEQLEeriaqlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1587 LGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKALEDKLELESAAKVELKRKAEQKIAAIR 1666
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 20127150   1667 KQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1713
Cdd:TIGR02168  894 SELEELSEE-----LRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 156-893 3.89e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.01  E-value: 3.89e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    156 SREQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREKKKLQGILSQSQdkslRRISELREELQMDQQAKKHLQDEF---D 232
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA----NEISRLEQQKQILRERLANLERQLeelE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    233 ACLEEKDQYISVLQTQVSLLKQRLQngpmnvdapkplppgELQAEVHGDTEKMEGVGEPVGGGTSAktLEMLQQRVKRQE 312
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEEKLE---------------ELKEELESLEAELEELEAELEELESR--LEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    313 NLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKM-KELHMAEKTKLITQLRDAKNLIEQLEQDKGMVIT--ET 389
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELlKKLEEAELKELQAELEELEEELEELQEELERLEEalEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    390 KRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEmDEQMKAVERASE 469
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVD-EGYEAAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    470 EerlRLQHELSR----VRQEAASMAKKN---------SEEQVAALQKLHAEELASKEQELSRRLEARERELQ-------- 528
Cdd:TIGR02168  545 G---RLQAVVVEnlnaAKKAIAFLKQNElgrvtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyl 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    529 -------EQMRIALE---KSRSEYLKLTQEKEQQESL-ALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLE 597
Cdd:TIGR02168  622 lggvlvvDDLDNALElakKLRPGYRIVTLDGDLVRPGgVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALA 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    598 --KSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQslSQQHQAAVEELREKYQQEKDA 675
Cdd:TIGR02168  702 elRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE--LEAEIEELEERLEEAEEELAE 779

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    676 LLKEKESLfQAHIQDMNEKtLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQRE 755
Cdd:TIGR02168  780 AEAEIEEL-EAQIEQLKEE-LKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL 857

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    756 VGSISEQQEltvrrAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAG 835
Cdd:TIGR02168  858 AAEIEELEE-----LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 20127150    836 AYEEQLAQMQQKVldleTEKSLLTKQvvEMETHKKHVCEELDAQRAQVQQLERQRSEL 893
Cdd:TIGR02168  933 GLEVRIDNLQERL----SEEYSLTLE--EAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1489-2157 3.95e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.01  E-value: 3.95e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1489 AREKEEQICLLKEDLDRQNKKFECLKGEmevrKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQ 1568
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1569 qrdtEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgELKALEDKLELES 1648
Cdd:TIGR02168  296 ----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------ELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1649 AAKVELKRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQ 1728
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1729 SVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--- 1805
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkal 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1806 ---------LIGCLPEELEEKMKCSLIVSQPMGE-----ETGNNTGVKQNWAS-------------VVDSVQKTLQEKEL 1858
Cdd:TIGR02168  512 lknqsglsgILGVLSELISVDEGYEAAIEAALGGrlqavVVENLNAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1859 TCQALEQRVKELESDLVRERGAHRLEVEKL---------------TLKYEKSQSSQQEMDGE--NKCVEVLEDRPEENSQ 1921
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnaleLAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1922 SHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKH 2001
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   2002 TSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDAREEEM 2081
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAAN-LRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   2082 TGKVTDLQTQLEELQKKYQQRLEQEESTKDSV-----TILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2156
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIeeleeLIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   .
gi 20127150   2157 A 2157
Cdd:TIGR02168  910 R 910
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 862-1713 5.43e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.64  E-value: 5.43e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    862 VVEMETHKKHVCEELDAQRaqvQQLERQRSELEEKVRSLAQLQDsqlknstvEKEQARQSLmekeniILQMREEQAKEIE 941
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVE---ENIERLDLIIDEKRQQLERLRR--------EREKAERYQ------ALLKEKREYEGYE 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    942 ILKQtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQIlEM 1021
Cdd:TIGR02169  228 LLKE-KEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEI-AS 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1022 AQANSAGISDTVSRLEENQRQQIESLtgahqRKLDDVIEAWEKKLSQQAAElRDKHAEQMEEKEQGLGELRQKVRIVQSE 1101
Cdd:TIGR02169  306 LERSIAEKERELEDAEERLAKLEAEI-----DKLLAEIEELEREIEEERKR-RDKLTEEYAELKEELEDLRAELEEVDKE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1102 KEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEElaelklladk 1181
Cdd:TIGR02169  380 FAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE---------- 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1182 sqlrVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCtsRDKADAI 1261
Cdd:TIGR02169  450 ----IKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVL--KASIQGV 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1262 LARLSQC----QRHTATVGEALLRRMGQV----SELEAQLTQLTEEQRTLKSSFQQVTN-QLEEKEKQIKTMKADIE--- 1329
Cdd:TIGR02169  524 HGTVAQLgsvgERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATFLPLNKmRDERRDLSILSEDGVIGfav 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1330 --------------------GLLTEKEALQQEGGQQRQAA-----SEKESCITQLKKELAENINAVTLLREELSEKKSEI 1384
Cdd:TIGR02169  604 dlvefdpkyepafkyvfgdtLVVEDIEAARRLMGKYRMVTlegelFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERL 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1385 ASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKA 1464
Cdd:TIGR02169  684 EGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKEL 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1465 QSRLAQHQSTIKDLQAQL-DVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVV 1543
Cdd:TIGR02169  764 EARIEELEEDLHKLEEALnDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1544 ELEDCVTQRKKEVESLN----------ETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLE 1613
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNgkkeeleeelEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELK 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1614 AELGTVKKELEHVNSSVKSrdgelkALEDKLELESAAKVELKRKA-EQKIAAIRKQLLSQMEEktqryAKDTENRLSELS 1692
Cdd:TIGR02169  924 AKLEALEEELSEIEDPKGE------DEEIPEEELSLEDVQAELQRvEEEIRALEPVNMLAIQE-----YEEVLKRLDELK 992

                          890       900
                   ....*....|....*....|.
gi 20127150   1693 AQLKEREKQVHSLEDKLKNLE 1713
Cdd:TIGR02169  993 EKRAKLEEERKAILERIEEYE 1013
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 507-1344 7.05e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.25  E-value: 7.05e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    507 EELASKEQELSRRLEARERELqEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAiLTESENKLQELGQEAEAYR 586
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENI-ERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYE-GYELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    587 TRILELETSLEKS---LQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLwtERLQSLSQQHQAAVE 663
Cdd:TIGR02169  244 RQLASLEEELEKLteeISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASL--ERSIAEKERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    664 ELREKYQQEKDALLKEKESL---------FQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDA 734
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEIEELereieeerkRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    735 DKMKQALEAELEEQRRHHQRevgsiseqqeltVRRAEKALKDELSRLGALlderdehlrerQARVQDLEAHLQKSAGELQ 814
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEE------------LADLNAAIAGIEAKINEL-----------EEEKEDKALEIKKQEWKLE 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    815 QALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKslltKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELE 894
Cdd:TIGR02169  459 QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA----RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVG 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    895 EK-VRSLAQLQDSQLKNSTVEKEQARQSLMEkenIILQMREEQAKEIEILKqtLSSKEESISILHEE----YETKFKNQE 969
Cdd:TIGR02169  535 ERyATAIEVAAGNRLNNVVVEDDAVAKEAIE---LLKRRKAGRATFLPLNK--MRDERRDLSILSEDgvigFAVDLVEFD 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    970 KRMEKIKQKA------KEMQETKKKLLDQEAKLKKELEntvlelsqkekqfnaqILEMAQANSAGiSDTVSRLEENQRQQ 1043
Cdd:TIGR02169  610 PKYEPAFKYVfgdtlvVEDIEAARRLMGKYRMVTLEGE----------------LFEKSGAMTGG-SRAPRGGILFSRSE 672

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1044 IESLtgahqRKLDDVIEAWEKKLSQQAAELRDKHAEqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVAL 1123
Cdd:TIGR02169  673 PAEL-----QRLRERLEGLKRELSSLQSELRRIENR-LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL 746

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1124 AGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGcSLSEKLSlQEELAELKLLADKSQLRVSELTGQVQAAEKELQSc 1203
Cdd:TIGR02169  747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALN-DLEARLS-HSRIPEIQAELSKLEEEVSRIEARLREIEQKLNR- 823

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1204 kslHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALleaktnelvctsRDKADAILARLSQCQRHTATVGEALLRRM 1283
Cdd:TIGR02169  824 ---LTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL------------NGKKEELEEELEELEAALRDLESRLGDLK 888

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 20127150   1284 GQVSELEAQLTQLTEEQRTLKSsfqqvtnQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQ 1344
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEA-------QIEKKRKRLSELKAKLEALEEELSEIEDPKGE 942
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 299-1042 9.19e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 9.19e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    299 KTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKElhmaEKTKLITQLRDAKNLIEQL 378
Cdd:TIGR02168  281 EEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE----ELAELEEKLEELKEELESL 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    379 EqDKGMVITETKRQMLETLELKEDEIAQLRSHIKQMttqgeelrEQKEKSERAAFEELEKALstaqktEDAQRRMKMEMD 458
Cdd:TIGR02168  357 E-AELEELEAELEELESRLEELEEQLETLRSKVAQL--------ELQIASLNNEIERLEARL------ERLEDRRERLQQ 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    459 EQMKAVERASEEERLRLQHELSRVRQEAAsmakkNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKS 538
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAELEELEEELE-----ELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    539 RSEYLkltqEKEQQESLALEELELQKKAILteseNKLQELGQEAEAYRTrilELETSLEKSLQE---SKTQSEHLAVHLE 615
Cdd:TIGR02168  497 LQENL----EGFSEGVKALLKNQSGLSGIL----GVLSELISVDEGYEA---AIEAALGGRLQAvvvENLNAAKKAIAFL 565

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    616 AEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQqhqaaVEELREKYQQEKDALLKekeslfQAHIQDMNEKT 695
Cdd:TIGR02168  566 KQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKD-----LVKFDPKLRKALSYLLG------GVLVVDDLDNA 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    696 LEKLDKKQMELESVSselsealRARDQLAEELSVLRGDADKMKQALEAELEeqRRHHQREVgSISEQQELTVRRAEKALK 775
Cdd:TIGR02168  635 LELAKKLRPGYRIVT-------LDGDLVRPGGVITGGSAKTNSSILERRRE--IEELEEKI-EELEEKIAELEKALAELR 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    776 DELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEK 855
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    856 SLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQM--- 932
Cdd:TIGR02168  785 EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIeel 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    933 ---REEQAKEIEILKQTLSSKEESISILHEEYEtkfkNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQ 1009
Cdd:TIGR02168  865 eelIEELESELEALLNERASLEEALALLRSELE----ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN 940

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 20127150   1010 KEKQFNAQ---ILEMAQANSAGISDTVSRLEENQRQ 1042
Cdd:TIGR02168  941 LQERLSEEyslTLEEAEALENKIEDDEEEARRRLKR 976
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 341-1108 9.11e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 67.69  E-value: 9.11e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    341 EQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEE 420
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    421 LREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAA 500
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    501 LQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQ 580
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    581 EAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQA 660
Cdd:pfam02463  406 EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQ 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    661 AVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQA 740
Cdd:pfam02463  486 LELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQK 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    741 LEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKL 820
Cdd:pfam02463  566 LVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    821 DLLHSEQSAAREQAgAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSL 900
Cdd:pfam02463  646 SGLRKGVSLEEGLA-EKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLA 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    901 AQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMeKIKQKAK 980
Cdd:pfam02463  725 DRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKL-KAQEEEL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    981 EMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIE 1060
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQK 883

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 20127150   1061 AWEKKLSQQAAELRDKHaEQMEEKEQGLGELRQKVRIVQSEKEELTKE 1108
Cdd:pfam02463  884 LKDELESKEEKEKEEKK-ELEEESQKLNLLEEKENEIEERIKEEAEIL 930
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1850-2154 3.78e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 3.78e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1850 QKTLQEKELTCQALEQRVKELESDLVRErgahrlEVEKLTLKYEKSQSSQQEMdgENKCVEVLEDRPEENSQSHEIQSNV 1929
Cdd:COG1196  219 KEELKELEAELLLLKLRELEAELEELEA------ELEELEAELEELEAELAEL--EAELEELRLELEELELELEEAQAEE 290

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1930 GTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQEldilkreceQEAEEKLKQEQEDLELKHTSTLKQLM 2009
Cdd:COG1196  291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL---------EEELEELEEELEEAEEELEEAEAELA 361

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 2010 REFNTQLAQKEQELERtvQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQ 2089
Cdd:COG1196  362 EAEEALLEAEAELAEA--EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 20127150 2090 TQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYE 2154
Cdd:COG1196  440 EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1516-2097 4.71e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 4.71e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1516 EMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRdtehSGLVQRLQHLEELGEEKDNKV 1595
Cdd:COG1196  236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE----YELLAELARLEQDIARLEERR 311

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1596 REAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEE 1675
Cdd:COG1196  312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1676 KTQryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCM 1755
Cdd:COG1196  392 LRA--AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1756 LQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLED--HVLIGCLPEELEEKMKCSLIVSQPMGEETG 1833
Cdd:COG1196  470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAglRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1834 NNtgvkqnwasVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLE 1913
Cdd:COG1196  550 NI---------VVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD 620

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1914 DRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQE 1993
Cdd:COG1196  621 TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1994 QEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAEL-------------LESHQEETQQLHRKIAEK- 2059
Cdd:COG1196  701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLeeealeelpeppdLEELERELERLEREIEALg 780

                        570       580       590       600
                 ....*....|....*....|....*....|....*....|....
gi 20127150 2060 ------EDDLRRTARRYeeildareEEMTGKVTDLQTQLEELQK 2097
Cdd:COG1196  781 pvnllaIEEYEELEERY--------DFLSEQREDLEEARETLEE 816
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 530-1216 1.20e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 64.09  E-value: 1.20e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    530 QMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKaiLTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEH 609
Cdd:pfam12128  231 QAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFG--YKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNG 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    610 LAVHLEAEKNKHNKELTALAEQHR------TEVEGLQQQQDSLWTERLQSLSQQHqAAVEELREKYQQEKDALLKEKESL 683
Cdd:pfam12128  309 ELSAADAAVAKDRSELEALEDQHGafldadIETAAADQEQLPSWQSELENLEERL-KALTGKHQDVTAKYNRRRSKIKEQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    684 FQAHIQDMNEKTLEKLDKKQMELESVSSELsEALRA--RDQLAEELSVLRGDADKMKQAL------------EAELEEQR 749
Cdd:pfam12128  388 NNRDIAGIKDKLAKIREARDRQLAVAEDDL-QALESelREQLEAGKLEFNEEEYRLKSRLgelklrlnqataTPELLLQL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    750 RHHQREVGSISEQQElTVRRAEKALKDELSRLGALLDERDEHLRERQARVQdleahlqksagELQQALAKLDLLHSEQSA 829
Cdd:pfam12128  467 ENFDERIERAREEQE-AANAEVERLQSELRQARKRRDQASEALRQASRRLE-----------ERQSALDELELQLFPQAG 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    830 A-----REQAGAYEEQLAQMQQKVLDLETEkslLTKQVVEMETHKKHVCE--ELDAQRAQV-------QQLERQRSELEE 895
Cdd:pfam12128  535 TllhflRKEAPDWEQSIGKVISPELLHRTD---LDPEVWDGSVGGELNLYgvKLDLKRIDVpewaaseEELRERLDKAEE 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    896 KV---RSLAQLQDSQLKnstvekeQARQSLmekeniilqmrEEQAKEIEILKQTLSSKEESISILHEEYET-KFKNQEKR 971
Cdd:pfam12128  612 ALqsaREKQAAAEEQLV-------QANGEL-----------EKASREETFARTALKNARLDLRRLFDEKQSeKDKKNKAL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    972 MEKIKQKAKEMQ--ETKKKLLDQEAKL-KKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLT 1048
Cdd:pfam12128  674 AERKDSANERLNslEAQLKQLDKKHQAwLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALE 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1049 GAHQRKLD--DVIEAWEKKLSQQAAELRDKhAEQMEEKEQGLGELRQKVRivqsekEELTKEVARLKEAVSGQDVALAGL 1126
Cdd:pfam12128  754 TWYKRDLAslGVDPDVIAKLKREIRTLERK-IERIAVRRQEVLRYFDWYQ------ETWLQRRPRLATQLSNIERAISEL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1127 QGQLEQKSA-VIVSLSERESQLQSQvEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSeLTGQVQAAEKELQSCKS 1205
Cdd:pfam12128  827 QQQLARLIAdTKLRRAKLEMERKAS-EKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGS-IGERLAQLEDLKLKRDY 904

                          730
                   ....*....|.
gi 20127150   1206 LHELSKKSLED 1216
Cdd:pfam12128  905 LSESVKKYVEH 915
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1461-2152 1.66e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.54  E-value: 1.66e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1461 KKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKM---EKKECDLETALKT 1537
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLanlERQLEELEAQLEE 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1538 QTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHsglvQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELG 1617
Cdd:TIGR02168  328 LESKLDELAEELAELEEKLEELKEELESLEAELEELE----AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1618 TVKKELEHVNSSVKSRDGELKALEDKLEL----ESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKdTENRLSELSA 1693
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEEaelkELQAELEELEEELEELQEELERLEEALEELREELEE-AEQALDAAER 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1694 QLKEREKQVHSLEDKLKNLE-------------SSPHPEVPAVSR------------------SMQSVAASPEQEAPDSQ 1742
Cdd:TIGR02168  483 ELAQLQARLDSLERLQENLEgfsegvkallknqSGLSGILGVLSElisvdegyeaaieaalggRLQAVVVENLNAAKKAI 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1743 DCTHKACKERLCMLQRRLSEKEKL----LRRLEQGEGEARP-----SQPEAQHRALSGKLDCTR-----------ARQLE 1802
Cdd:TIGR02168  563 AFLKQNELGRVTFLPLDSIKGTEIqgndREILKNIEGFLGVakdlvKFDPKLRKALSYLLGGVLvvddldnalelAKKLR 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1803 DHVLIGCLPEEL---------EEKMKCSLIVSQpmGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESD 1873
Cdd:TIGR02168  643 PGYRIVTLDGDLvrpggvitgGSAKTNSSILER--RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE 720

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1874 LVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLED-RPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK 1952
Cdd:TIGR02168  721 LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAeIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA 800

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1953 LSKEVARLQKELRALRREHQQeldilkreceqeAEEKLKQEQEDLELKhtstlKQLMREFNTQLAQKEQELERTVQEtID 2032
Cdd:TIGR02168  801 LREALDELRAELTLLNEEAAN------------LRERLESLERRIAAT-----ERRLEDLEEQIEELSEDIESLAAE-IE 862

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   2033 KAQEVEAELLESHQEETQQLhrkiaEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKds 2112
Cdd:TIGR02168  863 ELEELIEELESELEALLNER-----ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE-- 935

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 20127150   2113 VTILELQTQLAQK--------TTLISDSKLKEQELREQVHNLEDRLKR 2152
Cdd:TIGR02168  936 VRIDNLQERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKIKE 983
PTZ00121 PTZ00121
MAEBL; Provisional
 405-1153 1.71e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 63.62  E-value: 1.71e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   405 AQLRSHIKQM-----TTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHEL 479
Cdd:PTZ00121 1060 AEAKAHVGQDeglkpSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDA 1139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   480 SRVRQeaasmAKKNSEEQVAalqklhaeELASKEQELSRRLEARERE---LQEQMRIALEKSRSEYLKLTQEKEQQESLA 556
Cdd:PTZ00121 1140 RKAEE-----ARKAEDAKRV--------EIARKAEDARKAEEARKAEdakKAEAARKAEEVRKAEELRKAEDARKAEAAR 1206

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   557 LEELELQKKAILTESENKLQELGQEAEAYRTRILELETSlekslqESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEV 636
Cdd:PTZ00121 1207 KAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKA------EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA 1280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   637 EGLQQQQDSLWTERLQSLSQQHQaaVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEA 716
Cdd:PTZ00121 1281 DELKKAEEKKKADEAKKAEEKKK--ADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADE 1358

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   717 LRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQ---ELTVRRAEKALKDELSRLGALLDERDEhlR 793
Cdd:PTZ00121 1359 AEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKkadELKKAAAAKKKADEAKKKAEEKKKADE--A 1436

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   794 ERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVC 873
Cdd:PTZ00121 1437 KKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAK 1516

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   874 EELDAQRA-QVQQLERQRSELE----EKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENiilqmREEQAKEIEILKQTLS 948
Cdd:PTZ00121 1517 KAEEAKKAdEAKKAEEAKKADEakkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEED-----KNMALRKAEEAKKAEE 1591

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   949 SKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQ--ETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQans 1026
Cdd:PTZ00121 1592 ARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKkaEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAK--- 1668

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1027 agisdtvsRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELT 1106
Cdd:PTZ00121 1669 --------KAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAE 1740

                         730       740       750       760
                  ....*....|....*....|....*....|....*....|....*..
gi 20127150  1107 KEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEK 1153
Cdd:PTZ00121 1741 EDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDE 1787
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 155-743 2.74e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.65  E-value: 2.74e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  155 LSREQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREKKKLQGilsqsqdkslrRISELREELQMDQQAKKHLQDEFDAC 234
Cdd:COG1196  225 LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEA-----------ELEELRLELEELELELEEAQAEEYEL 293

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  235 LEEKDQyisvLQTQVSLLKQRLQngpmnvdapkplppgelQAEVHGDTEKMEGVGEPVGGGTSAKTLEMLQQRVKRQENL 314
Cdd:COG1196  294 LAELAR----LEQDIARLEERRR-----------------ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE 352

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  315 LQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVITETKRQML 394
Cdd:COG1196  353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAE 432

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  395 ETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLR 474
Cdd:COG1196  433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  475 LQHE--LSRVRQEAASMAKKNSEEQVAAlqklhAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQ 552
Cdd:COG1196  513 ALLLagLRGLAGAVAVLIGVEAAYEAAL-----EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAA 587

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  553 ESLALEELELQKKAILTESENKLQELGQEAEAYRT--RILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAE 630
Cdd:COG1196  588 LAAALARGAIGAAVDLVASDLREADARYYVLGDTLlgRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSR 667

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  631 QHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESlfQAHIQDMNEKTLEKLDKKQMELESVS 710
Cdd:COG1196  668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE--ELEEEALEEQLEAEREELLEELLEEE 745

                        570       580       590
                 ....*....|....*....|....*....|...
gi 20127150  711 SELSEALRARDQLAEELSVLRGDADKMKQALEA 743
Cdd:COG1196  746 ELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 298-1006 6.40e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.62  E-value: 6.40e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    298 AKTLEMLQQRVKRQ-ENLLQRCKETIGSHK---EQCALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDakn 373
Cdd:TIGR02169  271 EQLLEELNKKIKDLgEEEQLRVKEKIGELEaeiASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEE--- 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    374 liEQLEQDKGMVITETKRQMLETL----ELKEDEIAQLRSHIKQMTTQGEELREQKEKSERaafeELEKALSTAQKTEDA 449
Cdd:TIGR02169  348 --ERKRRDKLTEEYAELKEELEDLraelEEVDKEFAETRDELKDYREKLEKLKREINELKR----ELDRLQEELQRLSEE 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    450 QRRMKMEMdEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQvaalQKLHAeeLASKEQELSRRLEARERELQ- 528
Cdd:TIGR02169  422 LADLNAAI-AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE----QELYD--LKEEYDRVEKELSKLQRELAe 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    529 -EQMRIALEKSRSEYLKLTQEKEQ-------QESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKS- 599
Cdd:TIGR02169  495 aEAQARASEERVRGGRAVEEVLKAsiqgvhgTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGr 574

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    600 ---LQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTE------------VEGLQQQQDSLWTERLQSL---------- 654
Cdd:TIGR02169  575 atfLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEpafkyvfgdtlvVEDIEAARRLMGKYRMVTLegelfeksga 654

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    655 ----------SQQHQAAVEELREKYQQEKDALLKEKESLFQ--AHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQ 722
Cdd:TIGR02169  655 mtggsraprgGILFSRSEPAELQRLRERLEGLKRELSSLQSelRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEK 734

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    723 LAEELSVLRGDADKMKQALEAELEEQRRHHQRevgsISEQQEL--TVRRAEKALKDELSR-----LGALLDERDEHLRER 795
Cdd:TIGR02169  735 LKERLEELEEDLSSLEQEIENVKSELKELEAR----IEELEEDlhKLEEALNDLEARLSHsripeIQAELSKLEEEVSRI 810

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    796 QARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEE 875
Cdd:TIGR02169  811 EARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKE 890

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    876 LDAQRAQVQQLERQRSELEEKVrslaQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKE--IEILKQTLSSKEES 953
Cdd:TIGR02169  891 RDELEAQLRELERKIEELEAQI----EKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsLEDVQAELQRVEEE 966

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 20127150    954 ISILHE---EYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLE 1006
Cdd:TIGR02169  967 IRALEPvnmLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFME 1022
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 337-1181 7.39e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.24  E-value: 7.39e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    337 EALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMvITETKRQMLETLELKEDEIAQLRSHIKQMTT 416
Cdd:TIGR02169  201 ERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLAS-LEEELEKLTEEISELEKRLEEIEQLLEELNK 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    417 QGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVEraSEEERLRLQHELSRVRQEAASMAKKNSEE 496
Cdd:TIGR02169  280 KIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLE--AEIDKLLAEIEELEREIEEERKRRDKLTE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    497 QVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQ 576
Cdd:TIGR02169  358 EYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKIN 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    577 ELGQEAEAYRTRILELETSLEKSLQE-SKTQSEHLAvhLEAEKNKHNKELTALAEQH----------RTEVEGLQQQQDS 645
Cdd:TIGR02169  438 ELEEEKEDKALEIKKQEWKLEQLAADlSKYEQELYD--LKEEYDRVEKELSKLQRELaeaeaqarasEERVRGGRAVEEV 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    646 LWTER---------LQSLSQQHQAAVEEL-----------REKYQQEKDALLKEKEsLFQAHIQDMNEKTLEKLDKKQME 705
Cdd:TIGR02169  516 LKASIqgvhgtvaqLGSVGERYATAIEVAagnrlnnvvveDDAVAKEAIELLKRRK-AGRATFLPLNKMRDERRDLSILS 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    706 LESVSSELSEALRARDQLAEELSVLRGDA---DKMKQA-----------LEAELEEQ--------RRHHQREVGSISEQQ 763
Cdd:TIGR02169  595 EDGVIGFAVDLVEFDPKYEPAFKYVFGDTlvvEDIEAArrlmgkyrmvtLEGELFEKsgamtggsRAPRGGILFSRSEPA 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    764 EL-TVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQalakldlLHSEQSAAREQAGAYEEQLA 842
Cdd:TIGR02169  675 ELqRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ-------LEQEEEKLKERLEELEEDLS 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    843 QMQQKVLDLEtekslltkqvvemethkkhvcEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNSTVEKEQArqs 921
Cdd:TIGR02169  748 SLEQEIENVK---------------------SELKELEARIEELEEDLHKLEEALNDLeARLSHSRIPEIQAELSKL--- 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    922 lmekeniilqmrEEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELE 1001
Cdd:TIGR02169  804 ------------EEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELE 871

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1002 NTVLELSQKEKQFnaqilemaqansAGISDTVSRLEENQRQQiesltgahqrklddvieawEKKLSQQAAELrdkhaeqm 1081
Cdd:TIGR02169  872 ELEAALRDLESRL------------GDLKKERDELEAQLREL-------------------ERKIEELEAQI-------- 912

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1082 EEKEQGLGELRQKVRIVQSEKEELTKEVARLKEaVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCS 1161
Cdd:TIGR02169  913 EKKRKRLSELKAKLEALEEELSEIEDPKGEDEE-IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDEL 991

                          890       900
                   ....*....|....*....|
gi 20127150   1162 LSEKLSLQEELAELKLLADK 1181
Cdd:TIGR02169  992 KEKRAKLEEERKAILERIEE 1011
PTZ00121 PTZ00121
MAEBL; Provisional
 1440-2156 8.11e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.31  E-value: 8.11e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1440 SKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDV-KATDAREKEEQICLLKEDLDRQNKKFECLKGEME 1518
Cdd:PTZ00121 1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDArKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1519 VRKSKMEKKEcdlETALKTQTAR-VVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVRE 1597
Cdd:PTZ00121 1163 ARKAEEARKA---EDAKKAEAARkAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1598 AE----ETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQkiaAIRKQLLSQM 1673
Cdd:PTZ00121 1240 EEakkaEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE---AKKKAEEAKK 1316

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1674 EEKTQRYAKDTENRLSELSAQLKEREKQvhslEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERL 1753
Cdd:PTZ00121 1317 ADEAKKKAEEAKKKADAAKKKAEEAKKA----AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK 1392

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1754 CMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETG 1833
Cdd:PTZ00121 1393 ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA 1472

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1834 NNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLE 1913
Cdd:PTZ00121 1473 DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1914 dRPEENSQSHEIQSnvgtVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAE-EKLKQ 1992
Cdd:PTZ00121 1553 -KAEELKKAEEKKK----AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKaEELKK 1627

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1993 EQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVE---AELLESHQEETQQLHRKIAEKEDDLRRTA-- 2067
Cdd:PTZ00121 1628 AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDkkkAEEAKKAEEDEKKAAEALKKEAEEAKKAEel 1707

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  2068 -------RRYEEILDAREEEMTGKVTDLQTQLEElQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELR 2140
Cdd:PTZ00121 1708 kkkeaeeKKKAEELKKAEEENKIKAEEAKKEAEE-DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786

                         730
                  ....*....|....*.
gi 20127150  2141 EQVHNLEDRLKRYEKN 2156
Cdd:PTZ00121 1787 EEDEKRRMEVDKKIKD 1802
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 833-1715 9.10e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 61.22  E-value: 9.10e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    833 QAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRseleeKVRSLAQLQDSQLKNST 912
Cdd:TIGR00606  180 SATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSR-----EIVKSYENELDPLKNRL 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    913 VEKEQARQSLMEKENII-------LQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQET 985
Cdd:TIGR00606  255 KEIEHNLSKIMKLDNEIkalksrkKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    986 KKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVieaweKK 1065
Cdd:TIGR00606  335 RRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEA-----KT 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1066 LSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSEres 1145
Cdd:TIGR00606  410 AAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERE--- 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1146 qlQSQVEKlEADLGCSLSEKLSLQEELAELklladksqlrvseltgqvqaaekELQSCKSLHELSKKSLEDKSLNLKSLL 1225
Cdd:TIGR00606  487 --LSKAEK-NSLTETLKKEVKSLQNEKADL-----------------------DRKLRKLDQEMEQLNHHTTTRTQMEML 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1226 EELASQLDSRCERTKAlleaktnelvctsrdKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKS 1305
Cdd:TIGR00606  541 TKDKMDKDEQIRKIKS---------------RHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQ 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1306 SFQQVTNQLEEKEKQIKTMKADI------EGLLTEKEALQQE---GGQQRQAASEKESCITQLKKELAENINAVTLLREE 1376
Cdd:TIGR00606  606 NKNHINNELESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEiekSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQR 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1377 LSEKKSEIASLSKQLSDLgaqlesSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNK 1456
Cdd:TIGR00606  686 VFQTEAELQEFISDLQSK------LRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRD 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1457 FSEWKKKAQSRLAQHQSTIKDLQAQLDVKA--TDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLEta 1534
Cdd:TIGR00606  760 IQRLKNDIEEQETLLGTIMPEEESAKVCLTdvTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHE-- 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1535 LKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRlQHLEELGEEKDNKVREAEETVLRLREHVSSLEA 1614
Cdd:TIGR00606  838 LDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRR-QQFEEQLVELSTEVQSLIREIKDAKEQDSPLET 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1615 elgTVKKELEHVNSSVKSRDGELKALEDKLElesaakvELKRKAEQKIAAiRKQLLSQMEEKTQRYAKDTENRLSELSAQ 1694
Cdd:TIGR00606  917 ---FLEKDQQEKEELISSKETSNKKAQDKVN-------DIKEKVKNIHGY-MKDIENKIQDGKDDYLKQKETELNTVNAQ 985

                          890       900
                   ....*....|....*....|.
gi 20127150   1695 LKEREKQVHSLEDKLKNLESS 1715
Cdd:TIGR00606  986 LEECEKHQEKINEDMRLMRQD 1006
PTZ00121 PTZ00121
MAEBL; Provisional
 1454-2114 9.43e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.31  E-value: 9.43e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1454 SNKFSEWKKKAQSRLAQHQSTIKDLQAQLDV-KATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKME----KKE 1528
Cdd:PTZ00121 1169 ARKAEDAKKAEAARKAEEVRKAEELRKAEDArKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEakkaEEE 1248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1529 CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGE--EKDNKVREAEETVLRLR 1606
Cdd:PTZ00121 1249 RNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAK 1328

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1607 EHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEqkiAAIRKQLLSQMEEKTQRYAKDTEN 1686
Cdd:PTZ00121 1329 KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD---AAKKKAEEKKKADEAKKKAEEDKK 1405

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1687 RLSELSAQlKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKL 1766
Cdd:PTZ00121 1406 KADELKKA-AAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKK 1484

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1767 LRRLEQGEGEARPSQPEAQHRAlSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVV 1846
Cdd:PTZ00121 1485 ADEAKKKAEEAKKKADEAKKAA-EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEK 1563

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1847 DSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQ 1926
Cdd:PTZ00121 1564 KKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEA 1643

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1927 SNVGTVDGLRSDLESKLTGAERDKQKlSKEVARLQKELRALRREHQQELDILKRECEQ--EAEEKLKQEQEDLELKHTST 2004
Cdd:PTZ00121 1644 EEKKKAEELKKAEEENKIKAAEEAKK-AEEDKKKAEEAKKAEEDEKKAAEALKKEAEEakKAEELKKKEAEEKKKAEELK 1722

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  2005 LKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGK 2084
Cdd:PTZ00121 1723 KAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802

                         650       660       670
                  ....*....|....*....|....*....|
gi 20127150  2085 VTDLQTQLEELQKKYQQRLEQEESTKDSVT 2114
Cdd:PTZ00121 1803 IFDNFANIIEGGKEGNLVINDSKEMEDSAI 1832
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 403-998 9.55e-09

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 60.52  E-value: 9.55e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    403 EIAQLRSHIKQMTTQgeelREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRV 482
Cdd:pfam05557    3 ELIESKARLSQLQNE----KKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELN 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    483 RQEAASMAKKNSEEQVAALQKLHAEELAS-KEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELE 561
Cdd:pfam05557   79 RLKKKYLEALNKKLNEKESQLADAREVIScLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNL 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    562 LQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHleaEKNKHNKELTALAEQHRTEVEGLQQ 641
Cdd:pfam05557  159 EKQQSSLAEAEQRIKELEFEIQSQEQDSEIVKNSKSELARIPELEKELERLR---EHNKHLNENIENKLLLKEEVEDLKR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    642 QQDSlwterlQSLSQQHQAAVEELREKYQQEkdalLKEKESLFQAHIQDMNE--------KTLEKLDKKQME-LESVSSE 712
Cdd:pfam05557  236 KLER------EEKYREEAATLELEKEKLEQE----LQSWVKLAQDTGLNLRSpedlsrriEQLQQREIVLKEeNSSLTSS 305

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    713 LSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRRHHQREVGSISEQQELtVRRAEKALKDELSrlgalldeRDEHL 792
Cdd:pfam05557  306 ARQLEKARRELEQELAQYLKKIEDLNKKLK-RHKALVRRLQRRVLLLTKERDG-YRAILESYDKELT--------MSNYS 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    793 RERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVldlETEKSLLTKQVVEmethkkHV 872
Cdd:pfam05557  376 PQLLERIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQE---SLADPSYSKEEVD------SL 446

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    873 CEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVekeqarqsLMEKENIILQMREEQAKEIEILKQTLSSKEE 952
Cdd:pfam05557  447 RRKLETLELERQRLREQKNELEMELERRCLQGDYDPKKTKV--------LHLSMNPAAEAYQQRKNQLEKLQAEIERLKR 518

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 20127150    953 SISILHEEYETKfknQEKRMEKIKQKAKEMQETKKKLLDQEAKLKK 998
Cdd:pfam05557  519 LLKKLEDDLEQV---LRLPETTSTMNFKEVLDLRKELESAELKNQR 561
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
341-935 1.17e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.46  E-value: 1.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   341 EQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVITETKRQMLETLELKEdEIAQLRSHIKQMTTQGEE 420
Cdd:PRK03918  161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELRE-ELEKLEKEVKELEELKEE 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   421 LREQKEK--SERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVE--RASEEERLRLQHELSRVRQEAASMAKKNS-- 494
Cdd:PRK03918  240 IEELEKEleSLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYLDELREIEKRLSrl 319

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   495 EEQVAALQKL--HAEELASKEQELSRRLEARERELQEqmriaLEKSRSEYLKLTQEKEQqeslaleeLELQKKAILTESE 572
Cdd:PRK03918  320 EEEINGIEERikELEEKEERLEELKKKLKELEKRLEE-----LEERHELYEEAKAKKEE--------LERLKKRLTGLTP 386

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   573 NKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTA---LAEQHRTEVeglqQQQDSLWTE 649
Cdd:PRK03918  387 EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCgreLTEEHRKEL----LEEYTAELK 462

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   650 RLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQME-LESVSSELSEALRARDQLAEELS 728
Cdd:PRK03918  463 RIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEeLEKKAEEYEKLKEKLIKLKGEIK 542

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   729 VLRGDADKMK--QALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEhLRERQARVQDLEAHL 806
Cdd:PRK03918  543 SLKKELEKLEelKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLE-LKDAEKELEREEKEL 621

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   807 QKSAGELQQALAKLDLLHSEQSAAREQAGAY-----EEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRA 881
Cdd:PRK03918  622 KKLEEELDKAFEELAETEKRLEELRKELEELekkysEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKE 701

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....
gi 20127150   882 QVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREE 935
Cdd:PRK03918  702 ELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEE 755
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1288-2103 1.35e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.46  E-value: 1.35e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1288 ELEAQLTQLteEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENI 1367
Cdd:TIGR02168  217 ELKAELREL--ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1368 NAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSAL 1447
Cdd:TIGR02168  295 NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1448 EQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQL-DVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEK 1526
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQIASLNNEIERLEARLeRLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1527 KECDLETALKTQTARVVELEDCVTQRKKEVESLN---ETLKNYNQQRDTEHSGLVQRLQHLEELGE---------EKDNK 1594
Cdd:TIGR02168  455 ELERLEEALEELREELEEAEQALDAAERELAQLQarlDSLERLQENLEGFSEGVKALLKNQSGLSGilgvlseliSVDEG 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1595 VREAEETVlrLREHVSSLEAElgTVKKELEHVNSSVKSRDGELKALEdkLELESAAKVELKRKAEQKIAAIRKQLLSQME 1674
Cdd:TIGR02168  535 YEAAIEAA--LGGRLQAVVVE--NLNAAKKAIAFLKQNELGRVTFLP--LDSIKGTEIQGNDREILKNIEGFLGVAKDLV 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1675 EKTQRYAKDTENRLS------------ELSAQLKEREKQVhSLEDKLknleSSPHPEVPAVSRSMQSVAASPEQEAPDSQ 1742
Cdd:TIGR02168  609 KFDPKLRKALSYLLGgvlvvddldnalELAKKLRPGYRIV-TLDGDL----VRPGGVITGGSAKTNSSILERRREIEELE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1743 DCThKACKERLCMLQRRLSEKEKLLRRLEQGEGEAR--PSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKC 1820
Cdd:TIGR02168  684 EKI-EELEEKIAELEKALAELRKELEELEEELEQLRkeLEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1821 SLIVSQPMGEETGNNTGVKQNWASVVDSVQKtlqekeltcqaLEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQ 1900
Cdd:TIGR02168  763 IEELEERLEEAEEELAEAEAEIEELEAQIEQ-----------LKEELKALREALDELRAELTLLNEEAANLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1901 EMDGENKCVEVLEDRPEENSQSHE-IQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALR---REHQQELD 1976
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIEsLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSeelRELESKRS 911

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1977 ILKRECE--QEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLaqkeQELERTVQETIDKAQEVEAElLESHQEETQQLHR 2054
Cdd:TIGR02168  912 ELRRELEelREKLAQLELRLEGLEVRIDNLQERLSEEYSLTL----EEAEALENKIEDDEEEARRR-LKRLENKIKELGP 986

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 20127150   2055 KIAEKEDDLRRTARRYEEiLDAREEEMTGKVTDLQTQLEELQKKYQQRL 2103
Cdd:TIGR02168  987 VNLAAIEEYEELKERYDF-LTAQKEDLTEAKETLEEAIEEIDREARERF 1034
PTZ00121 PTZ00121
MAEBL; Provisional
 273-709 1.88e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.15  E-value: 1.88e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   273 ELQAEVHGDTEKMEGVGEPVGGGTSAKTLEMLQQRVKRQENLLQRCKEtigSHKEQCALLLSEKEALQEQLDERLQELEK 352
Cdd:PTZ00121 1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEE---AKKADEAKKKAEEAKKAEEAKKKAEEAKK 1471

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   353 MKELH--MAEKTKLITQLRDAKNLIEQLEQDKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSER 430
Cdd:PTZ00121 1472 ADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADEL 1551

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   431 AAFEELEKALSTAQ----KTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAAsmaKKNSEEQVAALQKLHA 506
Cdd:PTZ00121 1552 KKAEELKKAEEKKKaeeaKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEA---KKAEEAKIKAEELKKA 1628

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   507 EELASKEQELSRRlEARERELQEQMRIALE--KSRSEYLKLTQEKEQQESLALEELELQKKAIlTESENKLQELGQEAEA 584
Cdd:PTZ00121 1629 EEEKKKVEQLKKK-EAEEKKKAEELKKAEEenKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKA-AEALKKEAEEAKKAEE 1706

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   585 YRTRILELETSLE---KSLQESKTQSEHLavHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAA 661
Cdd:PTZ00121 1707 LKKKEAEEKKKAEelkKAEEENKIKAEEA--KKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE 1784

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 20127150   662 VEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESV 709
Cdd:PTZ00121 1785 LDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAI 1832
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1549-2154 2.20e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.69  E-value: 2.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1549 VTQRKKEVESLNETLKNYNQQRDTehsgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNS 1628
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEE----LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1629 SVKSRDGELKALEDKLELESAAKVELKRKAEQ--------------------KIAAIRKQLLSQMEEKTQRY------AK 1682
Cdd:TIGR02168  310 RLANLERQLEELEAQLEELESKLDELAEELAEleekleelkeelesleaeleELEAELEELESRLEELEEQLetlrskVA 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1683 DTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSE 1762
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1763 KEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV------------LIGCLPEELE--------------- 1815
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkallknqsglsgILGVLSELISvdegyeaaieaalgg 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1816 -----------------------EKMKCSLIV--------SQPMGEETGNNTGVKQNWASVVDSVQKTLQE--------- 1855
Cdd:TIGR02168  546 rlqavvvenlnaakkaiaflkqnELGRVTFLPldsikgteIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggv 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1856 ---KELTcQALEQRVKE--------LESDLVRERGAHRLEVEKLTLkyeKSQSSQQEMDGENKCVEVLEdrpeenSQSHE 1924
Cdd:TIGR02168  626 lvvDDLD-NALELAKKLrpgyrivtLDGDLVRPGGVITGGSAKTNS---SILERRREIEELEEKIEELE------EKIAE 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1925 IQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTST 2004
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   2005 LKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAEL------LESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDARE 2078
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELtllneeAANLRERLESLERRIAATERRLEDLEEQIEE-LSEDI 854

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 20127150   2079 EEMTGKVTDLQTQLEELQKKYQQRLEQEESTKdsVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYE 2154
Cdd:TIGR02168  855 ESLAAEIEELEELIEELESELEALLNERASLE--EALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 537-1003 2.21e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 59.65  E-value: 2.21e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    537 KSRSEYLKLTQEKEQQESLALEELE--LQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQE-SKTQSEHLAVH 613
Cdd:TIGR04523  121 KLEVELNKLEKQKKENKKNIDKFLTeiKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNiDKIKNKLLKLE 200

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    614 LE----AEKNKHNKELTA----LAEQHRTEVEGLQQQQDSL---------WTERLQSLSQQHQAAVEELREKYQQ--EKD 674
Cdd:TIGR04523  201 LLlsnlKKKIQKNKSLESqiseLKKQNNQLKDNIEKKQQEInektteisnTQTQLNQLKDEQNKIKKQLSEKQKEleQNN 280

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    675 ALLKEKESLFQA-----------HIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKmKQALEA 743
Cdd:TIGR04523  281 KKIKELEKQLNQlkseisdlnnqKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTN-SESENS 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    744 ELEEQRRHHQREVGSISEQQELTVRRAEKaLKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLL 823
Cdd:TIGR04523  360 EKQRELEEKQNEIEKLKKENQSYKQEIKN-LESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKN 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    824 HSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQL 903
Cdd:TIGR04523  439 NSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKK 518

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    904 QDSQLKNS---TVEKEQARQSLMEKENIILQMREEQAKEIeiLKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAK 980
Cdd:TIGR04523  519 ISSLKEKIeklESEKKEKESKISDLEDELNKDDFELKKEN--LEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEK 596

                          490       500
                   ....*....|....*....|....*.
gi 20127150    981 EMQETKKKLLDQEAK---LKKELENT 1003
Cdd:TIGR04523  597 EKKDLIKEIEEKEKKissLEKELEKA 622
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1285-1713 2.26e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.67  E-value: 2.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1285 QVSELEAQLTQLTEEQRTLKSSFQQVTNQL---EEKEKQIKTMKADIEGL-------LTEKEALQQEGGQQRQAASEKES 1354
Cdd:PRK02224  214 ELAELDEEIERYEEQREQARETRDEADEVLeehEERREELETLEAEIEDLretiaetEREREELAEEVRDLRERLEELEE 293

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1355 CITQLKKELA---ENINAVTLLREELSEKKSEIA-SLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQ 1430
Cdd:PRK02224  294 ERDDLLAEAGlddADAEAVEARREELEDRDEELRdRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELE 373

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1431 ELSLKVDAlSKEKMSALE-QVDHWSNKFS---EWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLlKEDLDRQ 1506
Cdd:PRK02224  374 EAREAVED-RREEIEELEeEIEELRERFGdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE-AEALLEA 451

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1507 NKKFECLK-----------GEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQrKKEVESLNETLKNYNQQRDTEHS 1575
Cdd:PRK02224  452 GKCPECGQpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRE 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1576 GLVQRLQHLEEL----------GEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNsSVKSRDGELKALEDKLE 1645
Cdd:PRK02224  531 TIEEKRERAEELreraaeleaeAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIE 609

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 20127150  1646 LESAAKVELKRKAEQKiaaiRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1713
Cdd:PRK02224  610 RLREKREALAELNDER----RERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELR 673
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
705-902 2.35e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 2.35e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  705 ELESVSSELSEALRARDQLAEelsvLRGDADKMKQALE--AELEEQRRHHQREVGsisEQQELTVRRAEKALKDELSRLG 782
Cdd:COG4913  236 DLERAHEALEDAREQIELLEP----IRELAERYAAARErlAELEYLRAALRLWFA---QRRLELLEAELEELRAELARLE 308

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  783 ALLDERDEHLRERQARVQDLEAHLQKSAGE-LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVL----DLETEKSL 857
Cdd:COG4913  309 AELERLEARLDALREELDELEAQIRGNGGDrLEQLEREIERLERELEERERRRARLEALLAALGLPLPasaeEFAALRAE 388

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 20127150  858 LTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQ 902
Cdd:COG4913  389 AAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
993-1397 2.40e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.67  E-value: 2.40e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   993 EAKLKKELENTVLELSQKEKQFNAQIlemaqansagisdtvSRLEENQRQQIESLTgahqrKLDDVIEAWEKKLsqqaae 1072
Cdd:PRK02224  197 EEKEEKDLHERLNGLESELAELDEEI---------------ERYEEQREQARETRD-----EADEVLEEHEERR------ 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1073 lrdkhaEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVE 1152
Cdd:PRK02224  251 ------EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1153 KLEADL-------GCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSL------ 1219
Cdd:PRK02224  325 ELRDRLeecrvaaQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdap 404

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1220 ----NLKSLLEELASQLD-----------------SRCERTKALLEA----------KTNELVCT---SRDKADAILARL 1265
Cdd:PRK02224  405 vdlgNAEDFLEELREERDelrereaeleatlrtarERVEEAEALLEAgkcpecgqpvEGSPHVETieeDRERVEELEAEL 484

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1266 SQCQRHTATVgEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQ 1345
Cdd:PRK02224  485 EDLEEEVEEV-EERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEA 563

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 20127150  1346 RQAASEKESCITQLKKELAENINAVTLLR------EELSEKKSEIASLSKQLSDLGAQ 1397
Cdd:PRK02224  564 EEEAEEAREEVAELNSKLAELKERIESLErirtllAAIADAEDEIERLREKREALAEL 621
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
478-1003 2.61e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 2.61e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  478 ELSRVRQEAASMakknsEEQVAALQKLhaEELASKEQELSRRLEARERELQeqmrialeksrseylKLTQEKEQQESLAL 557
Cdd:COG4913  236 DLERAHEALEDA-----REQIELLEPI--RELAERYAAARERLAELEYLRA---------------ALRLWFAQRRLELL 293

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  558 EELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVE 637
Cdd:COG4913  294 EAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGL 373

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  638 GLQQQQDSLWteRLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHiqdmnektlEKLDKKQMELESVSSEL-SEA 716
Cdd:COG4913  374 PLPASAEEFA--ALRAEAAALLEALEEELEALEEALAEAEAALRDLRREL---------RELEAEIASLERRKSNIpARL 442

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  717 LRARDQLAEELSV-------------LRGDADKMKQALEAELEEQRR------HHQREVGSISEQQELTVR-RAEKALKD 776
Cdd:COG4913  443 LALRDALAEALGLdeaelpfvgelieVRPEEERWRGAIERVLGGFALtllvppEHYAAALRWVNRLHLRGRlVYERVRTG 522

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  777 ELSRLGALLDER-----------------DEHLRERQARV-----QDLEAH--------LQKSAGEL------------- 813
Cdd:COG4913  523 LPDPERPRLDPDslagkldfkphpfrawlEAELGRRFDYVcvdspEELRRHpraitragQVKGNGTRhekddrrrirsry 602

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  814 ---QQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLtkqvvemETHKKHVCEELDAQ--RAQVQQLER 888
Cdd:COG4913  603 vlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAL-------QRLAEYSWDEIDVAsaEREIAELEA 675

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  889 QRSELEEKVRSLAQLQD--SQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISI-LHEEYETKF 965
Cdd:COG4913  676 ELERLDASSDDLAALEEqlEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERF 755

                        570       580       590
                 ....*....|....*....|....*....|....*...
gi 20127150  966 KNQEKRmEKIKQKAKEMQETKKKLLDQEAKLKKELENT 1003
Cdd:COG4913  756 AAALGD-AVERELRENLEERIDALRARLNRAEEELERA 792
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 962-1565 2.82e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 59.26  E-value: 2.82e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    962 ETKFKNQEKRMEKI----KQKAKEMQETKKKLLDQEAKlKKELENTVLELSQKEKQFNAQILEMAQANSAGISD-TVSRL 1036
Cdd:TIGR04523   32 DTEEKQLEKKLKTIknelKNKEKELKNLDKNLNKDEEK-INNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDlSKINS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1037 EENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAV 1116
Cdd:TIGR04523  111 EIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKE-LEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1117 SGQDVALAglqgQLEQKSAVIVSLSERESQLQSQVEKLEadlgcslseklslqEELAELKLLADKSQLRVSELTGQVQAA 1196
Cdd:TIGR04523  190 DKIKNKLL----KLELLLSNLKKKIQKNKSLESQISELK--------------KQNNQLKDNIEKKQQEINEKTTEISNT 251

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1197 EKELQSCKSLHELSKKSLEDKSLNL---KSLLEELASQLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTA 1273
Cdd:TIGR04523  252 QTQLNQLKDEQNKIKKQLSEKQKELeqnNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQIS 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1274 TVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKE 1353
Cdd:TIGR04523  332 QNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKD 411

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1354 SCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLES-SISPSDKAEAISALSKQHEEQELQLQAQLQEL 1432
Cdd:TIGR04523  412 EQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNlDNTRESLETQLKVLSRSINKIKQNLEQKQKEL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1433 SLKV---DALSKEKMSALEQVDHWSNKFSEWKKKAQ---SRLAQHQSTIKDLQAQLDVKATDAREKeeqicLLKEDLDRQ 1506
Cdd:TIGR04523  492 KSKEkelKKLNEEKKELEEKVKDLTKKISSLKEKIEkleSEKKEKESKISDLEDELNKDDFELKKE-----NLEKEIDEK 566

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 20127150   1507 NKKFECLKGEMEVRKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKN 1565
Cdd:TIGR04523  567 NKEIEELKQTQKSLKKKQEEKQelidqkekekKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKN 635
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1285-1715 3.12e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 59.26  E-value: 3.12e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1285 QVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELA 1364
Cdd:TIGR04523  219 QISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEIS 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1365 ENINAVTllREELSEKKSEIASLSKQLSDLGAQLESSISP-SDKAEAISALSKQHEEQELQLQAQLQELSLKVDA---LS 1440
Cdd:TIGR04523  299 DLNNQKE--QDWNKELKSELKNQEKKLEEIQNQISQNNKIiSQLNEQISQLKKELTNSESENSEKQRELEEKQNEiekLK 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1441 KEKMSALEQVDHWSNKFSEWKKKAQsrlaQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVR 1520
Cdd:TIGR04523  377 KENQSYKQEIKNLESQINDLESKIQ----NQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1521 K---SKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRdtehSGLVQRLQHLEELGEEKDNKVRE 1597
Cdd:TIGR04523  453 EliiKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEK----KELEEKVKDLTKKISSLKEKIEK 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1598 AEETVLRLREHVSSLEAELGTVKKEL--EHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKiAAIRKQLLSQMEE 1675
Cdd:TIGR04523  529 LESEKKEKESKISDLEDELNKDDFELkkENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQK-EKEKKDLIKEIEE 607

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 20127150   1676 KTQryakdtenRLSELSAQLKEREKQVHSLEDKLKNLESS 1715
Cdd:TIGR04523  608 KEK--------KISSLEKELEKAKKENEKLSSIIKNIKSK 639
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1550-2105 3.71e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.16  E-value: 3.71e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1550 TQRKKEVESLNETLKNYNQQRDTEHsgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEA--------ELGTVKK 1621
Cdd:COG4913  268 RERLAELEYLRAALRLWFAQRRLEL--LEAELEELRAELARLEAELERLEARLDALREELDELEAqirgnggdRLEQLER 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1622 ELEHVNSSVKSRDGELKALEDKLelesaAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQ 1701
Cdd:COG4913  346 EIERLERELEERERRRARLEALL-----AALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1702 VHSLEDKLKNLESSP---HPEVPAVSRSMQSVAASPEQEAP--------DSQDCTHKACKER------LCML--QRRLS- 1761
Cdd:COG4913  421 LRELEAEIASLERRKsniPARLLALRDALAEALGLDEAELPfvgelievRPEEERWRGAIERvlggfaLTLLvpPEHYAa 500

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1762 -----EKEKLLRRL---EQGEGEARPSQPEAQHRALSGKLD----------------------CTRARQLEDH---VLIG 1808
Cdd:COG4913  501 alrwvNRLHLRGRLvyeRVRTGLPDPERPRLDPDSLAGKLDfkphpfrawleaelgrrfdyvcVDSPEELRRHpraITRA 580

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1809 CL---PEELEEKmkcslivsqpmgeetGNNTGVKQNWASVVDSVQKtLQEKELTCQALEQRVKELESDLVRERGAHRLEV 1885
Cdd:COG4913  581 GQvkgNGTRHEK---------------DDRRRIRSRYVLGFDNRAK-LAALEAELAELEEELAEAEERLEALEAELDALQ 644

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1886 EKLTL--KYEKSQSSQQEMDGENKCVEVLEDRPEE----NSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVAR 1959
Cdd:COG4913  645 ERREAlqRLAEYSWDEIDVASAEREIAELEAELERldasSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQ 724

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1960 LQKELRALRREHQQELDILKRECEQEAEEKLKQE-QEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVE 2038
Cdd:COG4913  725 AEEELDELQDRLEAAEDLARLELRALLEERFAAAlGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAET 804

                        570       580       590       600       610       620
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 20127150 2039 AELLES--HQEETQQLHRKIaeKEDDLrrtARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQ 2105
Cdd:COG4913  805 ADLDADleSLPEYLALLDRL--EEDGL---PEYEERFKELLNENSIEFVADLLSKLRRAIREIKERIDP 868
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2182-2225 4.35e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 51.07  E-value: 4.35e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 20127150    2182 PTEFEYLRKVMFEYMMGRET--KTMAKVITTVLKFPDDQAQKILER 2225
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 853-1668 8.89e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.82  E-value: 8.89e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    853 TEKSLLTKQVVEMETHKKHVceeldaQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQM 932
Cdd:pfam15921   49 TQIPIFPKYEVELDSPRKII------AYPGKEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEM 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    933 REEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLkKELENTVLELSQKEK 1012
Cdd:pfam15921  123 QMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVL-QEIRSILVDFEEASG 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1013 QFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGaHQRKLDDVIEAWEKKLSQQAAELRDKHAEQME----EKEQGL 1088
Cdd:pfam15921  202 KKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKG-RIFPVEDQLEALKSESQNKIELLLQQHQDRIEqlisEHEVEI 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1089 GELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVS-LSERESQLQSQVEKLEADLGCSLSEKLS 1167
Cdd:pfam15921  281 TGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSeLREAKRMYEDKIEELEKQLVLANSELTE 360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1168 LQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckSLHELSKKSLEDKSLNLKSLLEELASQLDSR---CERTKALLE 1244
Cdd:pfam15921  361 ARTERDQFSQESGNLDDQLQKLLADLHKREKEL----SLEKEQNKRLWDRDTGNSITIDHLRRELDDRnmeVQRLEALLK 436

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1245 AKTNELVCTSRDKADAILARLSQCQRHTATVGE-----ALLRRMgqVSELEAQLTQLTEEQRT---LKSSFQQVTNQLEE 1316
Cdd:pfam15921  437 AMKSECQGQMERQMAAIQGKNESLEKVSSLTAQlestkEMLRKV--VEELTAKKMTLESSERTvsdLTASLQEKERAIEA 514

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1317 KEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEScitqLKKELAENINAVTLLREELSEKKSEIASLSKQLSDL-- 1394
Cdd:pfam15921  515 TNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEA----LKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMqv 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1395 -GAQLESSISpsdkaeaisalskqheeqelqlqaQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQS 1473
Cdd:pfam15921  591 eKAQLEKEIN------------------------DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLR 646

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1474 TIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRK 1553
Cdd:pfam15921  647 AVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAM 726

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1554 KEVESLNETLKNYNQQRDtehsGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSS---V 1630
Cdd:pfam15921  727 KVAMGMQKQITAKRGQID----ALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQerrL 802

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 20127150   1631 KSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQ 1668
Cdd:pfam15921  803 KEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQ 840
PTZ00121 PTZ00121
MAEBL; Provisional
 995-1713 1.16e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.46  E-value: 1.16e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   995 KLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELR 1074
Cdd:PTZ00121 1028 KIEELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTE 1107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1075 DKHAEQMEEKEQGLGELRQKVRIVQSEKEEltkEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSlseRESQLQSQVEKL 1154
Cdd:PTZ00121 1108 TGKAEEARKAEEAKKKAEDARKAEEARKAE---DARKAEEARKAEDAKRVEIARKAEDARKAEEA---RKAEDAKKAEAA 1181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1155 EADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAE-----KELQSCKSLHELSKKSLEDKSLNLKSLLEELA 1229
Cdd:PTZ00121 1182 RKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKkaeavKKAEEAKKDAEEAKKAEEERNNEEIRKFEEAR 1261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1230 SQLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTatvgeallRRMGQVSELEAQLTQLTEEQRTLKSSFQQ 1309
Cdd:PTZ00121 1262 MAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA--------DEAKKKAEEAKKADEAKKKAEEAKKKADA 1333

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1310 VTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAvtllrEELSEKKSEIASLSK 1389
Cdd:PTZ00121 1334 AKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA-----DEAKKKAEEDKKKAD 1408

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1390 QLSDLGAQLESSISPSDKAEAIsalsKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSrlA 1469
Cdd:PTZ00121 1409 ELKKAAAAKKKADEAKKKAEEK----KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEE--A 1482

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1470 QHQSTIKDLQAQLDVKATDAREKEEQicllKEDLDRQNKKFECLKGEmEVRKSKMEKKECDLETA---------LKTQTA 1540
Cdd:PTZ00121 1483 KKADEAKKKAEEAKKKADEAKKAAEA----KKKADEAKKAEEAKKAD-EAKKAEEAKKADEAKKAeekkkadelKKAEEL 1557

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1541 RVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEaelgtVK 1620
Cdd:PTZ00121 1558 KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEE-----EK 1632

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1621 KELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREK 1700
Cdd:PTZ00121 1633 KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEA 1712

                         730
                  ....*....|...
gi 20127150  1701 QVHSLEDKLKNLE 1713
Cdd:PTZ00121 1713 EEKKKAEELKKAE 1725
mukB PRK04863
chromosome partition protein MukB;
531-902 2.34e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 56.50  E-value: 2.34e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   531 MRIALEKSRSEYLKLTQEKEQQeslaleelelQKKAILTESENKLQELGQEAEAyrtrILELETSLEkslQESKTQSEHL 610
Cdd:PRK04863  275 MRHANERRVHLEEALELRRELY----------TSRRQLAAEQYRLVEMARELAE----LNEAESDLE---QDYQAASDHL 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   611 AVHLEAEK--NKHNK------ELTALAEQHRTEVEGLQQQQDSLWTE---------RLQSLSQQHQAAVEELREK---YQ 670
Cdd:PRK04863  338 NLVQTALRqqEKIERyqadleELEERLEEQNEVVEEADEQQEENEARaeaaeeevdELKSQLADYQQALDVQQTRaiqYQ 417

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   671 QEKDALLKEKE-----SLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVL--------RGDADKM 737
Cdd:PRK04863  418 QAVQALERAKQlcglpDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVrkiagevsRSEAWDV 497

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   738 KQALEAELEEQRRHHQREVGSISEQQELTVR-----RAEKALKDELSRLGALLDERDE---HLRERQARVQDLE---AHL 806
Cdd:PRK04863  498 ARELLRRLREQRHLAEQLQQLRMRLSELEQRlrqqqRAERLLAEFCKRLGKNLDDEDEleqLQEELEARLESLSesvSEA 577

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   807 QKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDletekSLLTKQvvEMETHKKHVCEELDAQRAQVQQL 886
Cdd:PRK04863  578 RERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGE-----EFEDSQ--DVTEYMQQLLERERELTVERDEL 650

                         410
                  ....*....|....*.
gi 20127150   887 ERQRSELEEKVRSLAQ 902
Cdd:PRK04863  651 AARKQALDEEIERLSQ 666
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1568-2152 2.70e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.10  E-value: 2.70e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1568 QQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLE-L 1646
Cdd:COG1196  221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELArL 300

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1647 ESAAKVELKRKAEqkIAAIRKQLLSQMEEKTQRYAKDTEnRLSELSAQLKEREKQVHSLEDKLKNLESSphpevpavsRS 1726
Cdd:COG1196  301 EQDIARLEERRRE--LEERLEELEEELAELEEELEELEE-ELEELEEELEEAEEELEEAEAELAEAEEA---------LL 368

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1727 MQSVAASPEQEApdsqdctHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARpsqpEAQHRALSGKLDCTRARQLEDHVL 1806
Cdd:COG1196  369 EAEAELAEAEEE-------LEELAEELLEALRAAAELAAQLEELEEAEEALL----ERLERLEEELEELEEALAELEEEE 437

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1807 IGCLPEELEEKmkcslivsqpmGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVE 1886
Cdd:COG1196  438 EEEEEALEEAA-----------EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGF 506

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1887 KLTLKYEKSQSSQQEMDGEnkcVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK-------LSKEVAR 1959
Cdd:COG1196  507 LEGVKAALLLAGLRGLAGA---VAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagratfLPLDKIR 583

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1960 LQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEA 2039
Cdd:COG1196  584 ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 2040 ELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDSVTILELQ 2119
Cdd:COG1196  664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743

                        570       580       590
                 ....*....|....*....|....*....|....*
gi 20127150 2120 TQLAQKTTLISD--SKLKEQELREQVHNLEDRLKR 2152
Cdd:COG1196  744 EEELLEEEALEElpEPPDLEELERELERLEREIEA 778
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 616-954 3.42e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.11  E-value: 3.42e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  616 AEKNKHNKELTALAEQHRTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQA----HIQDM 691
Cdd:COG3096  278 NERRELSERALELRRELFGARRQLAEEQYRL--VEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQekieRYQED 355

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  692 NEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaelEEQRR--HHQREVGSISEQQELTVRR 769
Cdd:COG3096  356 LEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALD---VQQTRaiQYQQAVQALEKARALCGLP 432

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  770 --AEKALKDELSRLGALLDERDEHLRERQARVQDLEAH----------LQKSAGE------------------------- 812
Cdd:COG3096  433 dlTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAArrqfekayelVCKIAGEversqawqtarellrryrsqqalaq 512

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  813 ----LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLER 888
Cdd:COG3096  513 rlqqLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRA 592

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 20127150  889 QRSELEEKVRSLAQLQDS--QLKNSTVEKEQARQSLMEKeniiLQMREEQAKEIEILKQTLSSKEESI 954
Cdd:COG3096  593 RIKELAARAPAWLAAQDAleRLREQSGEALADSQEVTAA----MQQLLEREREATVERDELAARKQAL 656
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 796-1017 3.78e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 3.78e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  796 QARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEE 875
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  876 LDAQRAQVQQLER--QRSELEEKVRSLAQLQDSQ--LKNSTVEKE--QARQSLMEKENIILQMREEQAKEIEILKQTLSS 949
Cdd:COG4942   99 LEAQKEELAELLRalYRLGRQPPLALLLSPEDFLdaVRRLQYLKYlaPARREQAEELRADLAELAALRAELEAERAELEA 178

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 20127150  950 KEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQ 1017
Cdd:COG4942  179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
390-925 3.92e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.69  E-value: 3.92e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  390 KRQMLETLELKEDeIAQLRSHIKQ---MTTQGEELREQKEKSE--RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV 464
Cdd:COG4913  214 REYMLEEPDTFEA-ADALVEHFDDlerAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRLWFAQRRLEL 292

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  465 ERAsEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALE-KSRSEYL 543
Cdd:COG4913  293 LEA-ELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARlEALLAAL 371

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  544 KLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKnkhnK 623
Cdd:COG4913  372 GLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALR----D 447

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  624 ELTALAEQHRTEV----EGLQ-QQQDSLWT---ERL---QSLS----QQHQAAVeelREKYQQEKDAL----LKEKESLF 684
Cdd:COG4913  448 ALAEALGLDEAELpfvgELIEvRPEEERWRgaiERVlggFALTllvpPEHYAAA---LRWVNRLHLRGrlvyERVRTGLP 524

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  685 QAHIQDMNEKTL-EKLDKK--------QMELESVSS--------ELSEALRA------------------RDQLAEELsV 729
Cdd:COG4913  525 DPERPRLDPDSLaGKLDFKphpfrawlEAELGRRFDyvcvdspeELRRHPRAitragqvkgngtrhekddRRRIRSRY-V 603

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  730 LRGDADKMKQALEAELEEQRRHHQRevgsiSEQQELTVRRAEKALKDELSRLGALLDerdehLRERQARVQDLEAHLQks 809
Cdd:COG4913  604 LGFDNRAKLAALEAELAELEEELAE-----AEERLEALEAELDALQERREALQRLAE-----YSWDEIDVASAEREIA-- 671

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  810 agELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDA-----QRAQVQ 884
Cdd:COG4913  672 --ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaedlaRLELRA 749

                        570       580       590       600
                 ....*....|....*....|....*....|....*....|...
gi 20127150  885 QLERQRSEL--EEKVRSLAQLQDSQLKNSTVEKEQARQSLMEK 925
Cdd:COG4913  750 LLEERFAAAlgDAVERELRENLEERIDALRARLNRAEEELERA 792
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 483-1094 5.06e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 55.23  E-value: 5.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    483 RQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEA-----RERELQEQMRIALEKSRSEYLKLTQEKEQQESLAL 557
Cdd:pfam12128  277 RQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAvakdrSELEALEDQHGAFLDADIETAAADQEQLPSWQSEL 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    558 EELELQKKAiLTESENKLQElgqeaeAYRTRILELetslekslqesktqSEHLAVHLEAEKNKHNKELTALAEQHrTEVE 637
Cdd:pfam12128  357 ENLEERLKA-LTGKHQDVTA------KYNRRRSKI--------------KEQNNRDIAGIKDKLAKIREARDRQL-AVAE 414

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    638 GLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEK----DALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSEL 713
Cdd:pfam12128  415 DDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKlrlnQATATPELLLQLENFDERIERAREEQEAANAEVERLQSEL 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    714 SEALRARDQLAEELSVLRGDADKMKQALEaELEEQ------RRHH--QREVGSISEQQELTVRRA------------EKA 773
Cdd:pfam12128  495 RQARKRRDQASEALRQASRRLEERQSALD-ELELQlfpqagTLLHflRKEAPDWEQSIGKVISPEllhrtdldpevwDGS 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    774 LKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAReqaGAYEEQLAQMQQKVLDLET 853
Cdd:pfam12128  574 VGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQAN---GELEKASREETFARTALKN 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    854 EKSLLTKQVVEMETHKKHVCEELDAQRA----QVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLM-EKENI 928
Cdd:pfam12128  651 ARLDLRRLFDEKQSEKDKKNKALAERKDsaneRLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEgALDAQ 730

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    929 ILQMREEQAKEIEILKQTLSS--------------KEESISILH---EEYETKFKNQEKRMEKIKQKAKEMQETkkkLLD 991
Cdd:pfam12128  731 LALLKAAIAARRSGAKAELKAletwykrdlaslgvDPDVIAKLKreiRTLERKIERIAVRRQEVLRYFDWYQET---WLQ 807

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    992 QEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgISDTVSRLEENQRQQIESLTG--AHQRKLDDVIEAWEKKLSQQ 1069
Cdd:pfam12128  808 RRPRLATQLSNIERAISELQQQLARLIADTKLRRAK-LEMERKASEKQQVRLSENLRGlrCEMSKLATLKEDANSEQAQG 886

                          650       660
                   ....*....|....*....|....*
gi 20127150   1070 AAELRDKHAEQMEEKEQGLGELRQK 1094
Cdd:pfam12128  887 SIGERLAQLEDLKLKRDYLSESVKK 911
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
802-1030 5.21e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 55.02  E-value: 5.21e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  802 LEAHLQKSAGELQQALAKLDllhSEQSAAREQAGAYEEQLAQMQQK--VLDLETEKSLLTKQVVEMETHKKHVCEELDAQ 879
Cdd:COG3206  162 LEQNLELRREEARKALEFLE---EQLPELRKELEEAEAALEEFRQKngLVDLSEEAKLLLQQLSELESQLAEARAELAEA 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  880 RAQVQQLERQRSELEEKVRSLAQLQ-----DSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESI 954
Cdd:COG3206  239 EARLAALRAQLGSGPDALPELLQSPviqqlRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASL 318

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  955 SILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL--LDQEAKLKKELENTVL------ELSQKEKQFNAQILEMAQANS 1026
Cdd:COG3206  319 EAELEALQAREASLQAQLAQLEARLAELPELEAELrrLEREVEVARELYESLLqrleeaRLAEALTVGNVRVIDPAVVPL 398


                 ....
gi 20127150 1027 AGIS 1030
Cdd:COG3206  399 KPVS 402
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
370-985 5.64e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.05  E-value: 5.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   370 DAKNLIEQLEQDKGMVITETKRQmLETLELKE--DEIAQLRSHIKQMTTQGEELREQKEKSeRAAFEELEKALSTAQKTE 447
Cdd:PRK02224  173 DARLGVERVLSDQRGSLDQLKAQ-IEEKEEKDlhERLNGLESELAELDEEIERYEEQREQA-RETRDEADEVLEEHEERR 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   448 DAQRRMKMEMDEQMKAVErASEEERLRLQHELSRVRQEAASMAKKNSEEQV-AALQKLHAEELASKEQELSRRLEARERE 526
Cdd:PRK02224  251 EELETLEAEIEDLRETIA-ETEREREELAEEVRDLRERLEELEEERDDLLAeAGLDDADAEAVEARREELEDRDEELRDR 329

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   527 LQEQmRIALEKSRSEYLKLTQEKEqqeslaleelelqkkailtesenklqELGQEAEAYRTRILELETSLEKSLQESKTQ 606
Cdd:PRK02224  330 LEEC-RVAAQAHNEEAESLREDAD--------------------------DLEERAEELREEAAELESELEEAREAVEDR 382

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   607 SEHLAvhleaeknkhnkELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQHQAAVE---ELREKYQQEKDALlKEKESL 683
Cdd:PRK02224  383 REEIE------------ELEEEIEELRERFGDAPVDLGNA-EDFLEELREERDELREreaELEATLRTARERV-EEAEAL 448

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   684 FQAHIQDMNEKTLEkldkkqmelesvSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEqrrhhqrevgsiSEQQ 763
Cdd:PRK02224  449 LEAGKCPECGQPVE------------GSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLER------------AEDL 504

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   764 ELTVRRAEKaLKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQ 843
Cdd:PRK02224  505 VEAEDRIER-LEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAE 583

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   844 MQQKVLDLETEKSLLtkqvvEMETHKKHVCEELDAQRAQVQQLERQR----SELEEKVRSL-AQLQDSQLKNSTVEKEQA 918
Cdd:PRK02224  584 LKERIESLERIRTLL-----AAIADAEDEIERLREKREALAELNDERrerlAEKRERKRELeAEFDEARIEEAREDKERA 658

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 20127150   919 RQSLMEKENIILQMREEQAKeieiLKQTLSSKEESISILHE--EYETKFKNQEKRMEKIKQKAKEMQET 985
Cdd:PRK02224  659 EEYLEQVEEKLDELREERDD----LQAEIGAVENELEELEElrERREALENRVEALEALYDEAEELESM 723
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 356-681 6.38e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 54.74  E-value: 6.38e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    356 LHMAEKTKLITQlRDAKNLIEQLEQDKGMVITETK-RQMLETLELKEDEIAQLRSHIKQMTTQGEELR---EQKEKSERA 431
Cdd:pfam17380  275 LHIVQHQKAVSE-RQQQEKFEKMEQERLRQEKEEKaREVERRRKLEEAEKARQAEMDRQAAIYAEQERmamERERELERI 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    432 AFEELEKALSTAQKTEDAQRRMKMEMDEQMKaVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELAS 511
Cdd:pfam17380  354 RQEERKRELERIRQEEIAMEISRMRELERLQ-MERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEA 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    512 KEQELSRRLEARERELqEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKlQELGQEAEAYRTRILE 591
Cdd:pfam17380  433 RQREVRRLEEERAREM-ERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRR-KILEKELEERKQAMIE 510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    592 LETslEKSLQESKTQSEHLAVHLEAEKNKHNKELTalAEQHRTEVEGLQQQQDSLWTERlqslsqQHQAAVEELREKYQQ 671
Cdd:pfam17380  511 EER--KRKLLEKEMEERQKAIYEEERRREAEEERR--KQQEMEERRRIQEQMRKATEER------SRLEAMEREREMMRQ 580

                          330
                   ....*....|
gi 20127150    672 EKDALLKEKE 681
Cdd:pfam17380  581 IVESEKARAE 590
PTZ00121 PTZ00121
MAEBL; Provisional
 701-1509 7.91e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.76  E-value: 7.91e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   701 KKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQRevgsiseqqeltVRRAEKALKDELSR 780
Cdd:PTZ00121 1085 EDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAED------------ARKAEEARKAEDAK 1152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   781 LGALLDERDEHLRERQARVQDlEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQlaQMQQKVLDLETEKSLltK 860
Cdd:PTZ00121 1153 RVEIARKAEDARKAEEARKAE-DAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEE--RKAEEARKAEDAKKA--E 1227

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   861 QVVEMETHKKhvcEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEI 940
Cdd:PTZ00121 1228 AVKKAEEAKK---DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA 1304

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   941 EILKQTLSSKEESisilhEEYETKFKNQEKRMEKIKQKAKEmqetkKKLLDQEAKLKKELENTVLELSQKEKQfnaqile 1020
Cdd:PTZ00121 1305 DEAKKKAEEAKKA-----DEAKKKAEEAKKKADAAKKKAEE-----AKKAAEAAKAEAEAAADEAEAAEEKAE------- 1367

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1021 maqansagiSDTVSRLEENQRQQiesltgAHQRKLDDVIEAWEKKlsqQAAELRDKHAEQMEEKEQGlgelrqkvrivQS 1100
Cdd:PTZ00121 1368 ---------AAEKKKEEAKKKAD------AAKKKAEEKKKADEAK---KKAEEDKKKADELKKAAAA-----------KK 1418

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1101 EKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAvivslsERESQLQSQVEKLEAdlgcslSEKLSLQEELAELKLLAD 1180
Cdd:PTZ00121 1419 KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKA------EEAKKAEEAKKKAEE------AKKADEAKKKAEEAKKAD 1486

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1181 KSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCTSRDKADA 1260
Cdd:PTZ00121 1487 EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKA 1566

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1261 ILARLSQCQRHTATVGEALLRRMGQVSELEaqLTQLTEEQRTLKSsfQQVTNQLEEKEKQIKTMKAdieglltekEALQQ 1340
Cdd:PTZ00121 1567 EEAKKAEEDKNMALRKAEEAKKAEEARIEE--VMKLYEEEKKMKA--EEAKKAEEAKIKAEELKKA---------EEEKK 1633

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1341 EGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQhee 1420
Cdd:PTZ00121 1634 KVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKK--- 1710

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1421 qelqlqaqLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLK 1500
Cdd:PTZ00121 1711 --------EAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE 1782


                  ....*....
gi 20127150  1501 EDLDRQNKK 1509
Cdd:PTZ00121 1783 EELDEEDEK 1791
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
299-790 8.05e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 54.66  E-value: 8.05e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   299 KTLEMLQQRVKRQENLLQRC---KETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELHMA---EKTKLITQLRDAK 372
Cdd:PRK02224  206 ERLNGLESELAELDEEIERYeeqREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAEterEREELAEEVRDLR 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   373 NLIEQLEQDKGMVITETKR---------QMLETLELKEDE----IAQLRSHIKQMTTQGEELREQ--------KEKSERA 431
Cdd:PRK02224  286 ERLEELEEERDDLLAEAGLddadaeaveARREELEDRDEElrdrLEECRVAAQAHNEEAESLREDaddleeraEELREEA 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   432 AfeELEKALSTAQKTEDAQRRMKMEMDEQMKAVERA----------SEEERLRLQHELSRVRQEAASMAK--KNSEEQVA 499
Cdd:PRK02224  366 A--ELESELEEAREAVEDRREEIEELEEEIEELRERfgdapvdlgnAEDFLEELREERDELREREAELEAtlRTARERVE 443

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   500 ALQKLHAeelASKEQELSRRLEARERElqeqmrIALEKSRSEYLKLTQEKEQQESLALEELELQKKAI-LTESENKLQEL 578
Cdd:PRK02224  444 EAEALLE---AGKCPECGQPVEGSPHV------ETIEEDRERVEELEAELEDLEEEVEEVEERLERAEdLVEAEDRIERL 514

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   579 GQEAEAYRTRILELETSLEKSlQESKTQSEHLAVHLEAEKNKHNKELTAL---AEQHRTEVEGLQQQQDSLwTERLQSLS 655
Cdd:PRK02224  515 EERREDLEELIAERRETIEEK-RERAEELRERAAELEAEAEEKREAAAEAeeeAEEAREEVAELNSKLAEL-KERIESLE 592

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   656 QqhQAAVEELREKYQQEKDALLKEKEslfqaHIQDMNEKTLEKLDKKQMELESVSSELSEAlrardqlaeELSVLRGDAD 735
Cdd:PRK02224  593 R--IRTLLAAIADAEDEIERLREKRE-----ALAELNDERRERLAEKRERKRELEAEFDEA---------RIEEAREDKE 656

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 20127150   736 KMKQALE------AELEEQRRHHQREVGSI-SEQQEL-TVRRAEKALKDELSRLGALLDERDE 790
Cdd:PRK02224  657 RAEEYLEqveeklDELREERDDLQAEIGAVeNELEELeELRERREALENRVEALEALYDEAEE 719
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 564-1680 2.01e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 53.52  E-value: 2.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    564 KKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQES---KTQSEHL---------------AVHLE--------AE 617
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEEENEDSihlEKEIKDLfdkyleiddeiiyinKLKLElkekikniSD 614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    618 KNKHNK---ELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQ--------- 685
Cdd:TIGR01612  615 KNEYIKkaiDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIYSTIKSELSKIYEDDIDALYNELSSIVKenaidnted 694

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    686 -AHIQDMNEKTLEKLDKKQ-MELESVSSELSEALRARDQLAEELSvlrgdadKMKQALEAELeeqrrhhQREVGSISEQq 763
Cdd:TIGR01612  695 kAKLDDLKSKIDKEYDKIQnMETATVELHLSNIENKKNELLDIIV-------EIKKHIHGEI-------NKDLNKILED- 759

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    764 eltVRRAEKALKdelSRLGALLDERDEhLRERQARVQDLEAHL--QKSAGELQQALAKLDLLHSEQSAarEQAGAYEEQL 841
Cdd:TIGR01612  760 ---FKNKEKELS---NKINDYAKEKDE-LNKYKSKISEIKNHYndQINIDNIKDEDAKQNYDKSKEYI--KTISIKEDEI 830

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    842 AQMQQKVLDLETEKSLLTKQVVEMETHKKhvcEELDAQRAQVQQL---------ERQRSELEEKVRSLAQLQDSqlKNST 912
Cdd:TIGR01612  831 FKIINEMKFMKDDFLNKVDKFINFENNCK---EKIDSEHEQFAELtnkikaeisDDKLNDYEKKFNDSKSLINE--INKS 905

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    913 VEKEQARQSLMEKENIILQM-----------REEQAKEIEILKQTLSSKEESISIlHEEYETKFKN----QEKRMEKIKQ 977
Cdd:TIGR01612  906 IEEEYQNINTLKKVDEYIKIcentkesiekfHNKQNILKEILNKNIDTIKESNLI-EKSYKDKFDNtlidKINELDKAFK 984

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    978 KAK------EMQETKKKLLDQEAKLKKELENTVL-ELSQKEKQFNAQILEMAQANS----------AGISDTVSRLEENQ 1040
Cdd:TIGR01612  985 DASlndyeaKNNELIKYFNDLKANLGKNKENMLYhQFDEKEKATNDIEQKIEDANKnipnieiaihTSIYNIIDEIEKEI 1064

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1041 RQQIESLTGAHQRKLDDVIEAWEK--------KLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKE---- 1108
Cdd:TIGR01612 1065 GKNIELLNKEILEEAEINITNFNEikeklkhyNFDDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKseny 1144

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1109 VARLKEAVSG-QDVALAGLQGQ----LEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQE----------ELA 1173
Cdd:TIGR01612 1145 IDEIKAQINDlEDVADKAISNDdpeeIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTSLEEvkginlsygkNLG 1224

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1174 ELKLLADKSQLRVSELTgqVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCT 1253
Cdd:TIGR01612 1225 KLFLEKIDEEKKKSEHM--IKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISD 1302

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1254 SRDKADAIL-----------------ARLSQCQRHTATVGEAL-----LRRMGQVSELEAQLTQLTEEQRTLKSSFQQVT 1311
Cdd:TIGR01612 1303 IREKSLKIIedfseesdindikkelqKNLLDAQKHNSDINLYLneianIYNILKLNKIKKIIDEVKEYTKEIEENNKNIK 1382

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1312 NQLEEKEKQIKTMKAD---------IEGLLTEK---EALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLRE-ELS 1378
Cdd:TIGR01612 1383 DELDKSEKLIKKIKDDinleeckskIESTLDDKdidECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNiEMA 1462

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1379 EKKSE-IASLSKQ--LSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKeKMSALEqvdhWSN 1455
Cdd:TIGR01612 1463 DNKSQhILKIKKDnaTNDHDFNINELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELLN-KYSALA----IKN 1537

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1456 KFSEWKKKAQSRLAQhqstIKDLQAQLDVKATDAREKEEQIcllkedldrqnkKFECLKGEMEVRKS-KMEKKECDLETA 1534
Cdd:TIGR01612 1538 KFAKTKKDSEIIIKE----IKDAHKKFILEAEKSEQKIKEI------------KKEKFRIEDDAAKNdKSNKAAIDIQLS 1601

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1535 LKTQTARVVELEDCVTQRK---KEVESLNETLKNYN-QQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETvlrlrehvs 1610
Cdd:TIGR01612 1602 LENFENKFLKISDIKKKINdclKETESIEKKISSFSiDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDK--------- 1672

                         1210      1220      1230      1240      1250      1260      1270
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 20127150   1611 sleaelgtvKKELEHVNSSVKSRDGELKALEDKLELESAAKV-ELKRKAEQKIAAIRKQLLSQMEEKTQRY 1680
Cdd:TIGR01612 1673 ---------KKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIkEIAIANKEEIESIKELIEPTIENLISSF 1734
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 303-917 2.12e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.20  E-value: 2.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    303 MLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLD---ERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLE 379
Cdd:pfam15921  261 LLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEiiqEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMY 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    380 QDKgmvITETKRQMLetleLKEDEIAQLRSHIKQMTTQGEELREQKEKSeRAAFEELEKALSTAQKTEDAQRRMKMEMDE 459
Cdd:pfam15921  341 EDK---IEELEKQLV----LANSELTEARTERDQFSQESGNLDDQLQKL-LADLHKREKELSLEKEQNKRLWDRDTGNSI 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    460 QMKAVERASEEERLRLQhELSRVRQEAASMAKKNSEEQVAALQKlhAEELASKEQELSRRLEARerelQEQMRIALEKSR 539
Cdd:pfam15921  413 TIDHLRRELDDRNMEVQ-RLEALLKAMKSECQGQMERQMAAIQG--KNESLEKVSSLTAQLEST----KEMLRKVVEELT 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    540 SEylKLTQEKEQQEslaleelelqkkaiLTESENKLQELGQEAEAYRTRILELETSLEKSLQE---SKTQSEHLAvHLEA 616
Cdd:pfam15921  486 AK--KMTLESSERT--------------VSDLTASLQEKERAIEATNAEITKLRSRVDLKLQElqhLKNEGDHLR-NVQT 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    617 EKNKHNKELTalaeQHRTEVEGLQQQQDSLwterLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTL 696
Cdd:pfam15921  549 ECEALKLQMA----EKDKVIEILRQQIENM----TQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKI 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    697 EKLDKKQMELESVSSEL----SEALRA-------RDQLAEELSVLRGDADKMKQALEAeleeqrrhHQREVGSISEQQEL 765
Cdd:pfam15921  621 RELEARVSDLELEKVKLvnagSERLRAvkdikqeRDQLLNEVKTSRNELNSLSEDYEV--------LKRNFRNKSEEMET 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    766 TVRRAEKALKDELSRLgallderdEHLRERQARVQDLEAHLQKSA-GELQQALAKLDLLHSEQSAAReqagAYEEQLAQM 844
Cdd:pfam15921  693 TTNKLKMQLKSAQSEL--------EQTRNTLKSMEGSDGHAMKVAmGMQKQITAKRGQIDALQSKIQ----FLEEAMTNA 760

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 20127150    845 QQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSlAQLQDSQLKNSTVEKEQ 917
Cdd:pfam15921  761 NKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDK-ASLQFAECQDIIQRQEQ 832
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 682-906 2.28e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 2.28e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  682 SLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALeAELEEQRRHHQREVGSISE 761
Cdd:COG4942   12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRI-RALEQELAALEAELAELEK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  762 QQElTVRRAEKALKDELSRLGALLderdehlrERQARVQDLEAHLqkSAGELQQALAKLDLLHSEQSAAREQAGAYEEQL 841
Cdd:COG4942   91 EIA-ELRAELEAQKEELAELLRAL--------YRLGRQPPLALLL--SPEDFLDAVRRLQYLKYLAPARREQAEELRADL 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 20127150  842 AQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDS 906
Cdd:COG4942  160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 761-1325 2.41e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.10  E-value: 2.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    761 EQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSeqsaareqagayeeQ 840
Cdd:TIGR04523  130 EKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKN--------------K 195

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    841 LAQMQQKVLDLETEKS---LLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQD---SQLKNSTVE 914
Cdd:TIGR04523  196 LLKLELLLSNLKKKIQknkSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNkikKQLSEKQKE 275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    915 KEQARQSLMEKENIILQMReeqaKEIEILKQtlsskeESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEA 994
Cdd:TIGR04523  276 LEQNNKKIKELEKQLNQLK----SEISDLNN------QKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQIS 345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    995 KLKKELENTVLELSQKEKQfnaqilemaqansagisdtvsrLEENQrQQIESLTGAHQRKLDDVieaweKKLSQQAAELR 1074
Cdd:TIGR04523  346 QLKKELTNSESENSEKQRE----------------------LEEKQ-NEIEKLKKENQSYKQEI-----KNLESQINDLE 397

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1075 DKHAEQMEEKEQglgeLRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKL 1154
Cdd:TIGR04523  398 SKIQNQEKLNQQ----KDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVL 473

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1155 EADLGCSLSEKLSLQEELAE-----LKLLADKSQL--RVSELTGQVQAA---EKELQSCKSLHELSKKSLEDKSLNLKSL 1224
Cdd:TIGR04523  474 SRSINKIKQNLEQKQKELKSkekelKKLNEEKKELeeKVKDLTKKISSLkekIEKLESEKKEKESKISDLEDELNKDDFE 553

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1225 L--EELASQLDSRCERTKALLEAKTNELVctSRDKADAILARLSQCQRhtaTVGEALLRRMGQVSELEAQLTQLTEEQRT 1302
Cdd:TIGR04523  554 LkkENLEKEIDEKNKEIEELKQTQKSLKK--KQEEKQELIDQKEKEKK---DLIKEIEEKEKKISSLEKELEKAKKENEK 628

                          570       580
                   ....*....|....*....|...
gi 20127150   1303 LKSSFQQVTNQLEEKEKQIKTMK 1325
Cdd:TIGR04523  629 LSSIIKNIKSKKNKLKQEVKQIK 651
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
306-885 2.44e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 2.44e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  306 QRVKRQENLLQRCKETIGSHKEQCALLLSEKEalQEQLDERLQELEKMKELHMAEKTKLITQLRDAKnliEQLEQDKGMV 385
Cdd:COG4913  265 AAARERLAELEYLRAALRLWFAQRRLELLEAE--LEELRAELARLEAELERLEARLDALREELDELE---AQIRGNGGDR 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  386 ITETKRQmLETLELKEDEIAQLRSHIKQMTTQGEElreqKEKSERAAFEEL-EKALSTAQKTEDAQRRMKMEMDEQMKAV 464
Cdd:COG4913  340 LEQLERE-IERLERELEERERRRARLEALLAALGL----PLPASAEEFAALrAEAAALLEALEEELEALEEALAEAEAAL 414

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  465 ERASEEERlRLQHELSRVRQeaasmAKKNSEEQVAALQKLHAEELASKEQELS--------RRLEAR-----EREL---- 527
Cdd:COG4913  415 RDLRRELR-ELEAEIASLER-----RKSNIPARLLALRDALAEALGLDEAELPfvgelievRPEEERwrgaiERVLggfa 488

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  528 ------QEQMRIALEKSRSEYLK--LTQEKEQQESLALEELELQKKAILteseNKLQELGQEAEAYRTRILELETSLEK- 598
Cdd:COG4913  489 ltllvpPEHYAAALRWVNRLHLRgrLVYERVRTGLPDPERPRLDPDSLA----GKLDFKPHPFRAWLEAELGRRFDYVCv 564

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  599 -SLQESKT---------QSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQhQAAVEELREK 668
Cdd:COG4913  565 dSPEELRRhpraitragQVKGNGTRHEKDDRRRIRSRYVLGFDNRAKLAALEAELAEL-EEELAEAEER-LEALEAELDA 642

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  669 YQQEKDALLKEKESLF--------QAHIQDmNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQA 740
Cdd:COG4913  643 LQERREALQRLAEYSWdeidvasaEREIAE-LEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKE 721

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  741 LEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDelsrlgALLDERDEHLRER-QARVQDLEAHLQKSAGELQQALAK 819
Cdd:COG4913  722 LEQAEEELDELQDRLEAAEDLARLELRALLEERFAA------ALGDAVERELRENlEERIDALRARLNRAEEELERAMRA 795

                        570       580       590       600       610       620       630
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 20127150  820 L----DLLHSEQSAAREQAGAYEEQLAQMQQKVL-DLETE-KSLLTKQvveMETHKKHVCEELDAQRAQVQQ 885
Cdd:COG4913  796 FnrewPAETADLDADLESLPEYLALLDRLEEDGLpEYEERfKELLNEN---SIEFVADLLSKLRRAIREIKE 864
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1185-1713 2.49e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.02  E-value: 2.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1185 RVSELTGQVQAAEK--ELQSCKSLHELSKKSLEDKSLNLK-SLLEELASQLDSRCERTKALLEAKTNEL------VCTSR 1255
Cdd:COG1196  201 QLEPLERQAEKAERyrELKEELKELEAELLLLKLRELEAElEELEAELEELEAELEELEAELAELEAELeelrleLEELE 280

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1256 DKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKssfqqvtNQLEEKEKQIKTMKADIEGLLTEK 1335
Cdd:COG1196  281 LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE-------EELEELEEELEELEEELEEAEEEL 353

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1336 EALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISpsdKAEAISALS 1415
Cdd:COG1196  354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE---ELEELEEAL 430

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1416 KQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQStiKDLQAQLDVKATDAREKEEQ 1495
Cdd:COG1196  431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLE 508

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1496 ICLLKEDLDRQNKKFECLKGEMEVRKSkmekkecdLETALktQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT--- 1572
Cdd:COG1196  509 GVKAALLLAGLRGLAGAVAVLIGVEAA--------YEAAL--EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflp 578

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1573 ----EHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGEL-KALEDKLELE 1647
Cdd:COG1196  579 ldkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLReVTLEGEGGSA 658

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 20127150 1648 SAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1713
Cdd:COG1196  659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 572-921 2.71e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 53.03  E-value: 2.71e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  572 ENKLQELGQEAEAYRTRILELETSLEK--SLQESKTQ--SEHLAVHLEAEKnkhnKELTALAEQHRTEVEGLQQQQdslw 647
Cdd:COG3096  784 EKRLEELRAERDELAEQYAKASFDVQKlqRLHQAFSQfvGGHLAVAFAPDP----EAELAALRQRRSELERELAQH---- 855

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  648 terlQSLSQQHQAAVEELREKyQQEKDALLKEKESLFQAHIQDMnektLEKLDKKQMELESVSSELSEALRARDQLAEEL 727
Cdd:COG3096  856 ----RAQEQQLRQQLDQLKEQ-LQLLNKLLPQANLLADETLADR----LEELREELDAAQEAQAFIQQHGKALAQLEPLV 926

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  728 SVLRGDA---DKMKQALEAELEEQRRHHQRevgsISEQQELTVRRAEKALKDELSRLGALlDERDEHLRER-----QARV 799
Cdd:COG3096  927 AVLQSDPeqfEQLQADYLQAKEQQRRLKQQ----IFALSEVVQRRPHFSYEDAVGLLGEN-SDLNEKLRARleqaeEARR 1001

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  800 QDLEAhLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSlltkqvvemETHKKHVCEELDAQ 879
Cdd:COG3096 1002 EAREQ-LRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEAEERA---------RIRRDELHEELSQN 1071

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 20127150  880 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 921
Cdd:COG3096 1072 RSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQA 1113
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 773-999 3.26e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 3.26e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  773 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLE 852
Cdd:COG4942   17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  853 TE----KSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENI 928
Cdd:COG4942   97 AEleaqKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE-ELRADLAELAALRAELEAERAE 175

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 20127150  929 ILQMREEQAKEIEILKQTLSSKEESISILheeyETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKE 999
Cdd:COG4942  176 LEALLAELEEERAALEALKAERQKLLARL----EKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1297-1509 3.75e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 3.75e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1297 TEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREE 1376
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1377 LSEKKSEIASLSKQLSDLGAQ--LESSISPSDKAEAISALS---------KQHEEQELQLQAQLQELSLKVDALSKEKMS 1445
Cdd:COG4942   99 LEAQKEELAELLRALYRLGRQppLALLLSPEDFLDAVRRLQylkylaparREQAEELRADLAELAALRAELEAERAELEA 178

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 20127150 1446 ALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKK 1509
Cdd:COG4942  179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 301-693 4.14e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.37  E-value: 4.14e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    301 LEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKE-LHMAEKTKLITQLRDAKNLIEQLE 379
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKdLARLEAEVEQLEERIAQLSKELTE 758

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    380 QDKGMVITETKRQMLET-LELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMkmemd 458
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEeLAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI----- 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    459 eqmkaverASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAE-ELASKEQELSRRLEARERELQEQMRIALEK 537
Cdd:TIGR02168  834 --------AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESElEALLNERASLEEALALLRSELEELSEELRE 905

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    538 SRSEYLKLTQEKEqqeslaleelelQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAE 617
Cdd:TIGR02168  906 LESKRSELRRELE------------ELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRR 973

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 20127150    618 KNKHNKELTALAEQHRTEVEGLQQQQdslwtERLQSLSQQHqAAVEELREKYQQEKDALLKEKESLFQAHIQDMNE 693
Cdd:TIGR02168  974 LKRLENKIKELGPVNLAAIEEYEELK-----ERYDFLTAQK-EDLTEAKETLEEAIEEIDREARERFKDTFDQVNE 1043
PRK11281 PRK11281
mechanosensitive channel MscK;
759-1109 4.23e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 52.22  E-value: 4.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   759 ISEQQELTVrrAEKALKDELSRLGALLDERDEHlrerQARVQDLEAHLQKSAGELQQALAKLDLL-HSEQSAAREQAGAY 837
Cdd:PRK11281   48 LNKQKLLEA--EDKLVQQDLEQTLALLDKIDRQ----KEETEQLKQQLAQAPAKLRQAQAELEALkDDNDEETRETLSTL 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   838 -----EEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSEL---------EEKVRSLAQL 903
Cdd:PRK11281  122 slrqlESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGkvggkalrpSQRVLLQAEQ 201

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   904 QDSQLKNstvekEQARQSLmeKENIILQM-----REEQAKEIEILKQTLSSKEESISilheeyetkfknqEKRMEKIKQK 978
Cdd:PRK11281  202 ALLNAQN-----DLQRKSL--EGNTQLQDllqkqRDYLTARIQRLEHQLQLLQEAIN-------------SKRLTLSEKT 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   979 AKEMQETKKK-------LLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQansagISDTVSRLEENQRQQIESLTGA- 1050
Cdd:PRK11281  262 VQEAQSQDEAariqanpLVAQELEINLQLSQRLLKATEKLNTLTQQNLRVKN-----WLDRLTQSERNIKEQISVLKGSl 336

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1051 --------HQRKL--DDVIeaweKKLSQQAAELRDKHAEQMEEKEQgLGELRQKV-RIVQSEKEELTKEV 1109
Cdd:PRK11281  337 llsrilyqQQQALpsADLI----EGLADRIADLRLEQFEINQQRDA-LFQPDAYIdKLEAGHKSEVTDEV 401
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1913-2156 4.51e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.37  E-value: 4.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1913 EDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK------LSKEVARLQKELRALR-REHQQELDILKREcEQE 1985
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKaerykeLKAELRELELALLVLRlEELREELEELQEE-LKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1986 AEEKLKQEQEDLELKHTStLKQLMREFNtQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRR 2065
Cdd:TIGR02168  251 AEEELEELTAELQELEEK-LEELRLEVS-ELEEEIEELQKELYALANEISRLEQQ-KQILRERLANLERQLEELEAQLEE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   2066 TARRYEEiLDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDSVTilELQTQLAQKTTLISDSKLKEQELREQVHN 2145
Cdd:TIGR02168  328 LESKLDE-LAEELAELEEKLEELKEELESLEAELEELEAELEELESRLE--ELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250
                   ....*....|.
gi 20127150   2146 LEDRLKRYEKN 2156
Cdd:TIGR02168  405 LEARLERLEDR 415
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1914-2156 5.98e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.84  E-value: 5.98e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1914 DRPEENSQSHEIQSNVGTVDGLRSDLESkltgaERDKQKLSKEVARLQKELRALRRE---HQQELDILKRECEQEAEEKL 1990
Cdd:COG4913  219 EEPDTFEAADALVEHFDDLERAHEALED-----AREQIELLEPIRELAERYAAARERlaeLEYLRAALRLWFAQRRLELL 293

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1991 KQEQEDLELKHTstlkqlmrefntQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRY 2070
Cdd:COG4913  294 EAELEELRAELA------------RLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRR 361

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 2071 EEiLDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDsvtilELQTQLAqkttlisDSKLKEQELREQVHNLEDRL 2150
Cdd:COG4913  362 AR-LEALLAALGLPLPASAEEFAALRAEAAALLEALEEELE-----ALEEALA-------EAEAALRDLRRELRELEAEI 428


                 ....*.
gi 20127150 2151 KRYEKN 2156
Cdd:COG4913  429 ASLERR 434
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 328-1002 8.58e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 51.12  E-value: 8.58e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    328 QCALLLSEKEALQEQLDERLQELEKMKELhmAEKTKLITQLRDAKNLIEQLEQDKGMVITETKRQML-ETLELKEDEIAQ 406
Cdd:TIGR00618  153 EFAQFLKAKSKEKKELLMNLFPLDQYTQL--ALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYhERKQVLEKELKH 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    407 LRSHIKQMTTQGEELREQKEKSERAafEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEA 486
Cdd:TIGR00618  231 LREALQQTQQSHAYLTQKREAQEEQ--LKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQ 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    487 ASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKka 566
Cdd:TIGR00618  309 AQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQ-- 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    567 ILTESENKLQELGQEAEAYRTrilELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQqqdsl 646
Cdd:TIGR00618  387 QKTTLTQKLQSLCKELDILQR---EQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEK----- 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    647 wterlqSLSQQHQAAVEELREKYQQEKDALLKEKEslfqahIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEE 726
Cdd:TIGR00618  459 ------IHLQESAQSLKEREQQLQTKEQIHLQETR------KKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPL 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    727 LSVLRGDADKMKQALEAELE-EQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAH 805
Cdd:TIGR00618  527 TRRMQRGEQTYAQLETSEEDvYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEA 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    806 LQKSAGELQQALAKLdllhsEQSAAREQAGAYEEQLAQMQQKvldletekSLLTKQVVEMETHKKHVCEELDAQRAQVQQ 885
Cdd:TIGR00618  607 EDMLACEQHALLRKL-----QPEQDLQDVRLHLQQCSQELAL--------KLTALHALQLTLTQERVREHALSIRVLPKE 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    886 LERQRSELEEKVRSLAQlQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKF 965
Cdd:TIGR00618  674 LLASRQLALQKMQSEKE-QLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQA 752

                          650       660       670
                   ....*....|....*....|....*....|....*..
gi 20127150    966 KNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELEN 1002
Cdd:TIGR00618  753 RTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQF 789
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1033-1713 8.76e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.27  E-value: 8.76e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1033 VSRLEENQRQQIESLtgahQRKLDDVIEAWEKK---LSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEV 1109
Cdd:pfam15921   76 IERVLEEYSHQVKDL----QRRLNESNELHEKQkfyLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1110 ARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLR---- 1185
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILReldt 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1186 -VSELTGQVQAAEKELQSCKSlhelskksledkslNLKSLLEELASQLDSRCERTKALLEAKTN---ELVCTSRDKADAI 1261
Cdd:pfam15921  232 eISYLKGRIFPVEDQLEALKS--------------ESQNKIELLLQQHQDRIEQLISEHEVEITgltEKASSARSQANSI 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1262 LARLSQCQRHTATVGEALLRrmgQVSELEAQLTQLTEEQRTLKSSFQqvtNQLEEKEKQIKTMKADIEGLLTEKEALQQE 1341
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMR---QLSDLESTVSQLRSELREAKRMYE---DKIEELEKQLVLANSELTEARTERDQFSQE 371

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1342 GG------QQRQAASEKESCITQLKKELAENI------NAVTL--LREELSEKKSEIASLSKQL----SDLGAQLESSIS 1403
Cdd:pfam15921  372 SGnlddqlQKLLADLHKREKELSLEKEQNKRLwdrdtgNSITIdhLRRELDDRNMEVQRLEALLkamkSECQGQMERQMA 451

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1404 P----SDKAEAISALSKQHEEQELQLQAQLQELSLKVDALS-------------KEKMSALEQVDHWSNKFS---EWKKK 1463
Cdd:pfam15921  452 AiqgkNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLEssertvsdltaslQEKERAIEATNAEITKLRsrvDLKLQ 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1464 AQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNK---KFECLKGEMEVRKSKMEKKECDLETALK---- 1536
Cdd:pfam15921  532 ELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgQHGRTAGAMQVEKAQLEKEINDRRLELQefki 611

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1537 ---TQTARVVELE----DCVTQRKKEVESLNETL---KNYNQQRDTEHSGLVQRLQHLEELGEEKD-------NKVREAE 1599
Cdd:pfam15921  612 lkdKKDAKIRELEarvsDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLSEDYEvlkrnfrNKSEEME 691

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1600 ETVLRLREHVSSLEAELGTVKKELEHVNSS--------------VKSRDGELKALEDKLELESAAKVELKRKaeqkiaai 1665
Cdd:pfam15921  692 TTTNKLKMQLKSAQSELEQTRNTLKSMEGSdghamkvamgmqkqITAKRGQIDALQSKIQFLEEAMTNANKE-------- 763

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 20127150   1666 rKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1713
Cdd:pfam15921  764 -KHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 834-1072 1.14e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 1.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  834 AGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNST 912
Cdd:COG4942   15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALeAELAELEKEIAE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  913 VEKEQARQSLMEKENIILQMREEQAKEIEILkqtLSSKEESISILHEEYETKF-KNQEKRMEKIKQKAKEMQETKKKLLD 991
Cdd:COG4942   95 LRAELEAQKEELAELLRALYRLGRQPPLALL---LSPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEA 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  992 QEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgisdtvsrlEENQRQQIESLTGAhQRKLDDVIEAWEKKLSQQAA 1071
Cdd:COG4942  172 ERAELEALLAELEEERAALEALKAERQKLLARLEKE---------LAELAAELAELQQE-AEELEALIARLEAEAAAAAE 241


                 .
gi 20127150 1072 E 1072
Cdd:COG4942  242 R 242
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1467-2156 1.21e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.84  E-value: 1.21e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1467 RLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELE 1546
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1547 DCVTQRKKEVESLNETLKNYNQQR-----------DTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAE 1615
Cdd:TIGR02169  265 KRLEEIEQLLEELNKKIKDLGEEEqlrvkekigelEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELERE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1616 LGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRkaEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQL 1695
Cdd:TIGR02169  345 IEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRD--ELKDYREKLEKLKREINELKRELDRLQEELQRLSEEL 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1696 KEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDctHKACKERLCMLQRRLSEKEKLLRRLEQGEG 1775
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE--LYDLKEEYDRVEKELSKLQRELAEAEAQAR 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1776 EARPSQPE-------------------------------AQHRALSGKL---------DCTRARQLEDHVLIGCLPEELE 1815
Cdd:TIGR02169  501 ASEERVRGgraveevlkasiqgvhgtvaqlgsvgeryatAIEVAAGNRLnnvvveddaVAKEAIELLKRRKAGRATFLPL 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1816 EKMKCSLIVSQPMGEETGNNTGV-----KQNWASVVDSV-QKTLQEKELTC---QALEQRVKELESDLVRERGA------ 1880
Cdd:TIGR02169  581 NKMRDERRDLSILSEDGVIGFAVdlvefDPKYEPAFKYVfGDTLVVEDIEAarrLMGKYRMVTLEGELFEKSGAmtggsr 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1881 --HRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVA 1958
Cdd:TIGR02169  661 apRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE 740

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1959 RLQKELRALRRE---HQQELDILKRECE--QEAEEKLKQEQEDLElkhtstlKQLMREFNTQLAQKEQELERTVQETIDK 2033
Cdd:TIGR02169  741 ELEEDLSSLEQEienVKSELKELEARIEelEEDLHKLEEALNDLE-------ARLSHSRIPEIQAELSKLEEEVSRIEAR 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   2034 AQEVEAELLESHQEEtQQLHRKIAEKEDDLRRTARRYEEIlDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDSV 2113
Cdd:TIGR02169  814 LREIEQKLNRLTLEK-EYLEKEIQELQEQRIDLKEQIKSI-EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKER 891

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 20127150   2114 TILE-----LQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2156
Cdd:TIGR02169  892 DELEaqlreLERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDP 939
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 621-1249 1.51e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.61  E-value: 1.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    621 HNKELTALAEQHRTEVEGLQQQQDSLWTERLQ-SLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKL 699
Cdd:pfam12128  228 RDIQAIAGIMKIRPEFTKLQQEFNTLESAELRlSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELN 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    700 DKKQMELESVSSELSEALRARDQ----LAEELSVLRGDADKMKQaLEAELEEQRRHHQREVGSISEQQELTVRRaEKALK 775
Cdd:pfam12128  308 GELSAADAAVAKDRSELEALEDQhgafLDADIETAAADQEQLPS-WQSELENLEERLKALTGKHQDVTAKYNRR-RSKIK 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    776 DELSRLGALLDERDEHLRERQARVQDL-EAHLQKSAGELQqalaklDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETE 854
Cdd:pfam12128  386 EQNNRDIAGIKDKLAKIREARDRQLAVaEDDLQALESELR------EQLEAGKLEFNEEEYRLKSRLGELKLRLNQATAT 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    855 KSLLTKQVVEMEThKKHVCEELDAQRAQVQQLERQRSELeekvRSLAQLQDSQLKNSTVEKEQARQSLMEKE-------- 926
Cdd:pfam12128  460 PELLLQLENFDER-IERAREEQEAANAEVERLQSELRQA----RKRRDQASEALRQASRRLEERQSALDELElqlfpqag 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    927 NIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVL- 1005
Cdd:pfam12128  535 TLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALq 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1006 -----------ELSQKEKQFNAQILEMAQANSA--GISDTVSRLEENQRQ---QIESLTGAHQRKLDDVIEAWEKKLSQQ 1069
Cdd:pfam12128  615 sarekqaaaeeQLVQANGELEKASREETFARTAlkNARLDLRRLFDEKQSekdKKNKALAERKDSANERLNSLEAQLKQL 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1070 AAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEEltkEVARLKEAVSGQDVALAGLQGQLEQKSA-----------VIV 1138
Cdd:pfam12128  695 DKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDA---QLALLKAAIAARRSGAKAELKALETWYKrdlaslgvdpdVIA 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1139 SLSERESQLQSQVEKLEADLGCSLSEKLSLQEE--LAELKLLADKSQLR--VSELTGQVQAAEKELQSCKSLHELSKKSL 1214
Cdd:pfam12128  772 KLKREIRTLERKIERIAVRRQEVLRYFDWYQETwlQRRPRLATQLSNIEraISELQQQLARLIADTKLRRAKLEMERKAS 851

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 20127150   1215 EDkslnLKSLLEELASQLDSRCERTKALLEAKTNE 1249
Cdd:pfam12128  852 EK----QQVRLSENLRGLRCEMSKLATLKEDANSE 882
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2183-2222 1.81e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 43.50  E-value: 1.81e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 20127150   2183 TEFEYLRKVMFEYMMGRET---KTMAKVITTVLKFPDDQAQKI 2222
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
COG5022 COG5022
Myosin heavy chain [General function prediction only];
310-933 2.13e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 50.08  E-value: 2.13e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  310 RQENLLQRCKETIGSHKEQCALllsEKEALQEQLDERLQELEK-MKELHMAEKTklITQLrdaKNLIEQLEQdkgmVITE 388
Cdd:COG5022  843 KAEVLIQKFGRSLKAKKRFSLL---KKETIYLQSAQRVELAERqLQELKIDVKS--ISSL---KLVNLELES----EIIE 910

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  389 TKRQ----MLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKT-EDAQRRMKMEMDEQMKA 463
Cdd:COG5022  911 LKKSlssdLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEyEDLLKKSTILVREGNKA 990

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  464 verasEEERLRLQHELS--RVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSE 541
Cdd:COG5022  991 -----NSELKNFKKELAelSKQYGALQESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQAR 1065

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  542 YLKLTQEKEQQESLALEELELQKKAIL----TESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAE 617
Cdd:COG5022 1066 YKALKLRRENSLLDDKQLYQLESTENLlktiNVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPV 1145

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  618 KNKHNKE---------LTALAEQHRTEVEGLQQQ----QDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESL- 683
Cdd:COG5022 1146 FQKLSVLqleldglfwEANLEALPSPPPFAALSEkrlyQSALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKk 1225

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  684 FQAHIQDMNEkTLEKLDkkqmelESVSSELSEALRARDQLAEELSVLRGDADKMK-QALEAELEEQRRHHQREVGSISEQ 762
Cdd:COG5022 1226 LISEGWVPTE-YSTSLK------GFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSsYKLEEEVLPATINSLLQYINVGLF 1298

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  763 QELTVRRAEKALK--DELSRLGALLDERDehlreRQARVQDLEAHLQksagELQQALAKLDLLHSEQSAAREqagayeeq 840
Cdd:COG5022 1299 NALRTKASSLRWKsaTEVNYNSEELDDWC-----REFEISDVDEELE----ELIQAVKVLQLLKDDLNKLDE-------- 1361

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  841 LAQMQQKVLDLETEKSLLTKQVVEMETH-KKHVCEELDAQRAQvqqlERQRSELEEKVRSLAQLQDS--------QLKNS 911
Cdd:COG5022 1362 LLDACYSLNPAEIQNLKSRYDPADKENNlPKEILKKIEALLIK----QELQLSLEGKDETEVHLSEIfseeksliSLDRN 1437

                        650       660
                 ....*....|....*....|....*
gi 20127150  912 TVEKEQARQSLME---KENIILQMR 933
Cdd:COG5022 1438 SIYKEEVLSSLSAlltKEKIALLDR 1462
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 670-1702 2.15e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 49.79  E-value: 2.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    670 QQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQR 749
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELE 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    750 RHHQREvgsisEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSA 829
Cdd:pfam01576   82 SRLEEE-----EERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    830 AREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLaQLQDSQLK 909
Cdd:pfam01576  157 LEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAEL-QAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    910 NSTVEKEQARQSLMEKeniilqMREEQAKEIEILKQtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL 989
Cdd:pfam01576  236 AQLAKKEEELQAALAR------LEEETAQKNNALKK-IRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL 308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    990 LD--------QEAKLKKELENTVLE--LSQKEKQFNAQILEMAQANSAGISDTVSRLE---------ENQRQQIESLTGA 1050
Cdd:pfam01576  309 EDtldttaaqQELRSKREQEVTELKkaLEEETRSHEAQLQEMRQKHTQALEELTEQLEqakrnkanlEKAKQALESENAE 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1051 HQRKLDDV------IEAWEKKLSQQAAELRDKHAE---QMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDV 1121
Cdd:pfam01576  389 LQAELRTLqqakqdSEHKRKKLEGQLQELQARLSEserQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLES 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1122 ALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQ 1201
Cdd:pfam01576  469 QLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKK 548

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1202 SCKSLHELSKKSLEDKSLNLKSL----------LEELASQLDSRCERTKAL---------LEAKTNELVCTSRDKADAIL 1262
Cdd:pfam01576  549 RLQRELEALTQQLEEKAAAYDKLektknrlqqeLDDLLVDLDHQRQLVSNLekkqkkfdqMLAEEKAISARYAEERDRAE 628

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1263 ARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEG 1342
Cdd:pfam01576  629 AEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDEL 708

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1343 GQQRQAASEKESCITQLKKELAENINAvtllREELSEKKSEiaSLSKQLSDLGAQLESsiSPSDKAEAISALSKqheeqe 1422
Cdd:pfam01576  709 QATEDAKLRLEVNMQALKAQFERDLQA----RDEQGEEKRR--QLVKQVRELEAELED--ERKQRAQAVAAKKK------ 774

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1423 lqLQAQLQELSLKVDALSKEKMSALEQVdhwsnkfsewkKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKED 1502
Cdd:pfam01576  775 --LELDLKELEAQIDAANKGREEAVKQL-----------KKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAE 841

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1503 L----------DRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT 1572
Cdd:pfam01576  842 LlqlqedlaasERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQ 921

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1573 EHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREhvssleaELGTVKKELEhvnSSVKSRDGELKALEDKLELES---A 1649
Cdd:pfam01576  922 LTTELAAERSTSQKSESARQQLERQNKELKAKLQE-------MEGTVKSKFK---SSIAALEAKIAQLEEQLEQESrerQ 991

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 20127150   1650 AKVELKRKAEQKIaairKQLLSQME------EKTQRYAKDTENRLSELSAQLKEREKQV 1702
Cdd:pfam01576  992 AANKLVRRTEKKL----KEVLLQVEderrhaDQYKDQAEKGNSRMKQLKRQLEEAEEEA 1046
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 959-1158 2.20e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.20e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  959 EEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgISDTVSRLEE 1038
Cdd:COG4942   23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE-IAELRAELEA 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1039 NQRQQIESLTGAHQRKLDDVIE---------------AWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKE 1103
Cdd:COG4942  102 QKEELAELLRALYRLGRQPPLAlllspedfldavrrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 20127150 1104 ELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADL 1158
Cdd:COG4942  182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 722-1353 2.84e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.58  E-value: 2.84e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    722 QLAEELSVLRGDADKMKQALEAELEEQRRHHQ--REVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARV 799
Cdd:TIGR00618  230 HLREALQQTQQSHAYLTQKREAQEEQLKKQQLlkQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    800 QDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAyeEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQ 879
Cdd:TIGR00618  310 QRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRL--LQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    880 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQArqsLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHE 959
Cdd:TIGR00618  388 KTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQL---AHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQES 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    960 EYETK-FKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQfnAQILEMAQANSAGISDTVSRLEE 1038
Cdd:TIGR00618  465 AQSLKeREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQD--IDNPGPLTRRMQRGEQTYAQLET 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1039 ----------NQRQQIESLTGAHQRKLDDVIEAWEK---------KLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQ 1099
Cdd:TIGR00618  543 seedvyhqltSERKQRASLKEQMQEIQQSFSILTQCdnrskedipNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQ 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1100 SE--KEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEAdlgcsLSEKLSLQEELAELKL 1177
Cdd:TIGR00618  623 PEqdLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLA-----LQKMQSEKEQLTYWKE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1178 LADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCtsrdk 1257
Cdd:TIGR00618  698 MLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTA----- 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1258 ADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQ--------LTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1329
Cdd:TIGR00618  773 ALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQeipsdediLNLQCETLVQEEEQFLSRLEEKSATLGEITHQLL 852

                          650       660
                   ....*....|....*....|....
gi 20127150   1330 GLLTEKEALQQEGGQQRQAASEKE 1353
Cdd:TIGR00618  853 KYEECSKQLAQLTQEQAKIIQLSD 876
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
169-834 3.21e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 3.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  169 RSLSSYRGKYSELVTAFQTLQREKKKLQGILSQSQdkslrRISELREELQMDQQAKKHLQDEFDA-CLEEKDQYISVLQT 247
Cdd:COG4913  228 DALVEHFDDLERAHEALEDAREQIELLEPIRELAE-----RYAAARERLAELEYLRAALRLWFAQrRLELLEAELEELRA 302

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  248 QVSLLKQRLQngpmnvdapkplppgELQAEvHGDTEKMEGVGEPVGGGTSAKTLEMLQQRVKRQENLLQRCKETIGSHKE 327
Cdd:COG4913  303 ELARLEAELE---------------RLEAR-LDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEA 366

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  328 QCALL-----LSEKE--ALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQdkgmvitetkrqmletlelk 400
Cdd:COG4913  367 LLAALglplpASAEEfaALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEA-------------------- 426

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  401 edEIAQLRSHIKQMTTQGEELReqkekseraafEELEKALSTAQ------------KTEDAQRRMKMEM----------- 457
Cdd:COG4913  427 --EIASLERRKSNIPARLLALR-----------DALAEALGLDEaelpfvgelievRPEEERWRGAIERvlggfaltllv 493

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  458 -DEQMKAVERASEEERLRLQHELSRVRQEAAsmakknSEEQVAALQKLHAEELASKEQELSRRLEAR------------E 524
Cdd:COG4913  494 pPEHYAAALRWVNRLHLRGRLVYERVRTGLP------DPERPRLDPDSLAGKLDFKPHPFRAWLEAElgrrfdyvcvdsP 567

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  525 REL-QEQMRIALE---KSRSEylklTQEKEQQESLALE----ELELQKKAILtesENKLQELGQEAEAYRTRILELETSL 596
Cdd:COG4913  568 EELrRHPRAITRAgqvKGNGT----RHEKDDRRRIRSRyvlgFDNRAKLAAL---EAELAELEEELAEAEERLEALEAEL 640

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  597 EkSLQESKTQSEHLAVHLEAEKNkhnkeltalAEQHRTEVEGLQQQQDSLWTE--RLQSLSQQHQAAVEELREkYQQEKD 674
Cdd:COG4913  641 D-ALQERREALQRLAEYSWDEID---------VASAEREIAELEAELERLDASsdDLAALEEQLEELEAELEE-LEEELD 709

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  675 ALLKEKESLFQAHIQdmnekTLEKLDKKQMELESVSSELSEALRARdqLAEELSVLRGDADkmKQALEAELEEQRRHHQR 754
Cdd:COG4913  710 ELKGEIGRLEKELEQ-----AEEELDELQDRLEAAEDLARLELRAL--LEERFAAALGDAV--ERELRENLEERIDALRA 780

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  755 EVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQA-RVQDLEAHLQKSAGEL-QQALAKLDLLHSEQSAARE 832
Cdd:COG4913  781 RLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRlEEDGLPEYEERFKELLnENSIEFVADLLSKLRRAIR 860


                 ..
gi 20127150  833 QA 834
Cdd:COG4913  861 EI 862
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
766-1380 4.27e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 4.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  766 TVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQ 845
Cdd:COG4913  236 DLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLE 315

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  846 QKVLDLETEKSLLTKQvvemetHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLqdsqLKNSTVEKEQARQSLmek 925
Cdd:COG4913  316 ARLDALREELDELEAQ------IRGNGGDRLEQLEREIERLERELEERERRRARLEAL----LAALGLPLPASAEEF--- 382

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  926 eniilqmrEEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELEnTVL 1005
Cdd:COG4913  383 --------AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALA-EAL 453

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1006 ELSQKEKQFNAQILEmaqansagisdtVSRLEENQRQQIESLTGAH-------QRKLDDVIEA-----WEKKLSQQAAEL 1073
Cdd:COG4913  454 GLDEAELPFVGELIE------------VRPEEERWRGAIERVLGGFaltllvpPEHYAAALRWvnrlhLRGRLVYERVRT 521

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1074 RDKHAEQMEEKEQGLGElrqKVRIVQSE-----KEELTKEVARLK----EAVSGQDVALAgLQGQLEQKSAV----IVSL 1140
Cdd:COG4913  522 GLPDPERPRLDPDSLAG---KLDFKPHPfrawlEAELGRRFDYVCvdspEELRRHPRAIT-RAGQVKGNGTRhekdDRRR 597

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1141 SERESQL-QSQVEKLEAdlgcslseklsLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSkksleDKSL 1219
Cdd:COG4913  598 IRSRYVLgFDNRAKLAA-----------LEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYS-----WDEI 661

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1220 NLKSLLEELASqldsrcertkalLEAKTNELvctsrDKADAILARLSQcqrhtatvgeallrrmgQVSELEAQLTQLTEE 1299
Cdd:COG4913  662 DVASAEREIAE------------LEAELERL-----DASSDDLAALEE-----------------QLEELEAELEELEEE 707

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1300 QRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSE 1379
Cdd:COG4913  708 LDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEE 787


                 .
gi 20127150 1380 K 1380
Cdd:COG4913  788 E 788
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 301-972 6.45e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.43  E-value: 6.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    301 LEMLQQRVKRQENLLQRCKETIGSHKEQCALLlSEKEALQEQLDERLQELEKMK--ELHMAEKTKLITQLRDAKNL---- 374
Cdd:TIGR00618  221 KQVLEKELKHLREALQQTQQSHAYLTQKREAQ-EEQLKKQQLLKQLRARIEELRaqEAVLEETQERINRARKAAPLaahi 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    375 --IEQLEQDKGMVITETKRQM--LETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQ 450
Cdd:TIGR00618  300 kaVTQIEQQAQRIHTELQSKMrsRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQ 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    451 RRMKMEMDEQmkaverASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERElQEQ 530
Cdd:TIGR00618  380 HIHTLQQQKT------TLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITC-TAQ 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    531 MRIALEKSRSEYLKLTQEKEQQESLALEELElQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHL 610
Cdd:TIGR00618  453 CEKLEKIHLQESAQSLKEREQQLQTKEQIHL-QETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQ 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    611 AvhLEAEKNKHNKELTALAEQHRTEVEGLQ--QQQDSLWTERLQSLSQQHQAAVEELrEKYQQEKDALLKEKESLFQAHI 688
Cdd:TIGR00618  532 R--GEQTYAQLETSEEDVYHQLTSERKQRAslKEQMQEIQQSFSILTQCDNRSKEDI-PNLQNITVRLQDLTEKLSEAED 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    689 QDMNEKTLEKLDK--------KQMELESVSSELSEALRARDQLAEELSvlrgdADKMKQALEAELEEQRRHHQREVGSIS 760
Cdd:TIGR00618  609 MLACEQHALLRKLqpeqdlqdVRLHLQQCSQELALKLTALHALQLTLT-----QERVREHALSIRVLPKELLASRQLALQ 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    761 EQQELtvRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDllHSEQSAAREQAGAYEEQ 840
Cdd:TIGR00618  684 KMQSE--KEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALN--QSLKELMHQARTVLKAR 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    841 LAQMQQKVLDLETEKSLLTkqvvEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQ 920
Cdd:TIGR00618  760 TEAHFNNNEEVTAALQTGA----ELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLS 835

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|..
gi 20127150    921 SLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRM 972
Cdd:TIGR00618  836 RLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQ 887
mukB PRK04863
chromosome partition protein MukB;
310-985 6.98e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.41  E-value: 6.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   310 RQENLLQRCKETIGSHKEQcallLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEqlEQDKGMVITET 389
Cdd:PRK04863  345 RQQEKIERYQADLEELEER----LEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALD--VQQTRAIQYQQ 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   390 KRQMLE-----------TLELKEDEIAQLRSHIKQMTTQGEELrEQKEKSERAAFEELEKALSTAQKT------EDAQR- 451
Cdd:PRK04863  419 AVQALErakqlcglpdlTADNAEDWLEEFQAKEQEATEELLSL-EQKLSVAQAAHSQFEQAYQLVRKIagevsrSEAWDv 497

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   452 -----------RMKMEMDEQMKAvERASEEERLRLQHELSRVRQEAASMAKK--NSEEQVAALQKLHAEELASKEQELSr 518
Cdd:PRK04863  498 arellrrlreqRHLAEQLQQLRM-RLSELEQRLRQQQRAERLLAEFCKRLGKnlDDEDELEQLQEELEARLESLSESVS- 575

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   519 rlEARERelQEQMRIALEKSRSEYLKLTQEKEQQESLALEELElqkkaiLTESENKLQELGQEAEAYRTRILELETSLEK 598
Cdd:PRK04863  576 --EARER--RMALRQQLEQLQARIQRLAARAPAWLAAQDALAR------LREQSGEEFEDSQDVTEYMQQLLERERELTV 645

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   599 SLQESKTQSEHLAVHLEAEKNKHNKE---LTALAEQHR----TEVEGLQQQQDSLWTERLqsLSQQHQAAV--------E 663
Cdd:PRK04863  646 ERDELAARKQALDEEIERLSQPGGSEdprLNALAERFGgvllSEIYDDVSLEDAPYFSAL--YGPARHAIVvpdlsdaaE 723

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   664 ELREKYQQEKDALLKE------KESLFQAhiQDMNEKTLEKLDKKQMELESVSSE----------LSEALRA-RDQLAEE 726
Cdd:PRK04863  724 QLAGLEDCPEDLYLIEgdpdsfDDSVFSV--EELEKAVVVKIADRQWRYSRFPEVplfgraarekRIEQLRAeREELAER 801

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   727 LSVLRGDADKMKQALE----------------------AELEEQRRHHQREVGSIsEQQELTVRRAEKALKDELSRLGAL 784
Cdd:PRK04863  802 YATLSFDVQKLQRLHQafsrfigshlavafeadpeaelRQLNRRRVELERALADH-ESQEQQQRSQLEQAKEGLSALNRL 880

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   785 LDE----RDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQagayEEQLAQMQQKVLDLETEKSLLTK 860
Cdd:PRK04863  881 LPRlnllADETLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSD----PEQFEQLKQDYQQAQQTQRDAKQ 956

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   861 Q------VVEMETH------KKHVCEELDAQ---RAQVQQLERQRSELEEKVR-SLAQLQD-----SQLKNSTVEKEQAR 919
Cdd:PRK04863  957 QafalteVVQRRAHfsyedaAEMLAKNSDLNeklRQRLEQAEQERTRAREQLRqAQAQLAQynqvlASLKSSYDAKRQML 1036

                         730       740       750       760       770       780
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 20127150   920 QSLM-EKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQET 985
Cdd:PRK04863 1037 QELKqELQDLGVPADSGAEERARARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERD 1103
Nup88 pfam10168
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ...
 916-1059 6.99e-05

Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.


Pssm-ID: 462975 [Multi-domain]  Cd Length: 713  Bit Score: 48.12  E-value: 6.99e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    916 EQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAK 995
Cdd:pfam10168  553 DLAREEIQKRVKLLKLQKEQQLQELQSLEEERKSLSERAEKLAEKYEEIKDKQEKLMRRCKKVLQRLNSQLPVLSDAERE 632

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 20127150    996 LKKELE--NTVLE-----LSQKEKQFNAQILEMAQANSAGISDTVSrLEENQRQQIESLTGAHQRKLDDVI 1059
Cdd:pfam10168  633 MKKELEtiNEQLKhlanaIKQAKKKMNYQRYQIAKSQSIRKKSSLS-LSEKQRKTIKEILKQLGSEIDELI 702
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 657-1016 7.27e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.20  E-value: 7.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    657 QHQAAVEElreKYQQEKdallkeKESLFQAHIQDMNEKTLEKLDKKQmelesvssELSEALRARDQLAEELSVLRGDADK 736
Cdd:pfam17380  279 QHQKAVSE---RQQQEK------FEKMEQERLRQEKEEKAREVERRR--------KLEEAEKARQAEMDRQAAIYAEQER 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    737 MKQALEAELEEQRRHHQREVGSISEQQELTVrraEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQA 816
Cdd:pfam17380  342 MAMERERELERIRQEERKRELERIRQEEIAM---EISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQ 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    817 LAKLDLLHSEQSAAReqagayeeqlaqmQQKVLDLETEKSLLTKQVVEMETHKKHVCEELdaqRAQVQQLERQRSELEEK 896
Cdd:pfam17380  419 KVEMEQIRAEQEEAR-------------QREVRRLEEERAREMERVRLEEQERQQQVERL---RQQEEERKRKKLELEKE 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    897 VRSLAQLQDSQLKNSTVEKEQARQSLMEKENiilqMREEQAKEIeilkqtlsskEESISILHEEYETKFKNQEKRMEKIK 976
Cdd:pfam17380  483 KRDRKRAEEQRRKILEKELEERKQAMIEEER----KRKLLEKEM----------EERQKAIYEEERRREAEEERRKQQEM 548

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 20127150    977 QKAKEMQETKKKLLDQEAKL-----KKELENTVLELSQKEKQFNA 1016
Cdd:pfam17380  549 EERRRIQEQMRKATEERSRLeamerEREMMRQIVESEKARAEYEA 593
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
707-904 7.56e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.09  E-value: 7.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  707 ESVSSELSEALRARDQLAEELSVLRGDADkmkqALEAELEEQRRHHQreVGSISEQQELTVRRaekalkdeLSRLGALLD 786
Cdd:COG3206  164 QNLELRREEARKALEFLEEQLPELRKELE----EAEAALEEFRQKNG--LVDLSEEAKLLLQQ--------LSELESQLA 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  787 ERDEHLRERQARVQDLEAHLQKSAGE---------LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSL 857
Cdd:COG3206  230 EARAELAEAEARLAALRAQLGSGPDAlpellqspvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQ 309

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 20127150  858 LTKQVVEMETHkkhvceELDAQRAQVQQLERQRSELEEKVRSLAQLQ 904
Cdd:COG3206  310 EAQRILASLEA------ELEALQAREASLQAQLAQLEARLAELPELE 350
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
772-1059 8.02e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 47.20  E-value: 8.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  772 KALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL 851
Cdd:COG4372   48 EQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDL 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  852 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQ-DSQLKNSTVEKEQARQSLMEKENIIL 930
Cdd:COG4372  128 EQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEaEQALDELLKEANRNAEKEEELAEAEK 207

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  931 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQK 1010
Cdd:COG4372  208 LIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEA 287

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 20127150 1011 EKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVI 1059
Cdd:COG4372  288 LEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILL 336
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
659-806 8.99e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.55  E-value: 8.99e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  659 QAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKtLEKLDKKQMELESVSSELSEALRARDQLAEElsvlrgdadkmk 738
Cdd:COG2433  379 EEALEELIEKELPEEEPEAEREKEHEERELTEEEEE-IRRLEEQVERLEAEVEELEAELEEKDERIER------------ 445

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 20127150  739 qaLEAELEEQRRhhqrevgsiSEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHL 806
Cdd:COG2433  446 --LERELSEARS---------EERREIRKDREISRLDREIERLERELEEERERIEELKRKLERLKELW 502
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
766-1250 9.67e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 9.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   766 TVRRAEKALKDELSRLG---ALLDERDEHLRERQARVQDLEAHLQKSAGELQQA---LAKLDLLHSEQSAAREQAGAYEE 839
Cdd:PRK03918  173 EIKRRIERLEKFIKRTEnieELIKEKEKELEEVLREINEISSELPELREELEKLekeVKELEELKEEIEELEKELESLEG 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   840 QLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVcEELDAQRAQVQQLERQRSELEEKVRSLAQLQD--SQLKNSTVEKEQ 917
Cdd:PRK03918  253 SKRKLEEKIRELEERIEELKKEIEELEEKVKEL-KELKEKAEEYIKLSEFYEEYLDELREIEKRLSrlEEEINGIEERIK 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   918 ARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK 997
Cdd:PRK03918  332 ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKIT 411

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   998 KELENTVLELSQKEKQFNA---------------------QILEMAQANSAGISDTVSRLEENQRQQIESLTGAH----- 1051
Cdd:PRK03918  412 ARIGELKKEIKELKKAIEElkkakgkcpvcgrelteehrkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEkvlkk 491

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1052 ------QRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSE---KEELTKEVARLKEAVSGQDVA 1122
Cdd:PRK03918  492 eselikLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKElekLEELKKKLAELEKKLDELEEE 571

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1123 LAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQS 1202
Cdd:PRK03918  572 LAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE 651

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|...
gi 20127150  1203 CKSL-----HELSKKSLEDKSLNLKSLLEELaSQLDSRCERTKALLEAKTNEL 1250
Cdd:PRK03918  652 LEKKyseeeYEELREEYLELSRELAGLRAEL-EELEKRREEIKKTLEKLKEEL 703
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 705-921 1.04e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.13  E-value: 1.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  705 ELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRRHHQREVGSISEQQEltvrraekALKDELSRLGAL 784
Cdd:COG3883   17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYN-ELQAELEALQAEIDKLQAEIA--------EAEAEIEERREE 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  785 LDERDEHLRERQARVQDLEAHLqkSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVE 864
Cdd:COG3883   88 LGERARALYRSGGSVSYLDVLL--GSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAE 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 20127150  865 METHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 921
Cdd:COG3883  166 LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAA 222
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1954-2165 1.20e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1954 SKEVARLQKELRALRREHQQELDILKREceQEAEEKLKQEQEDLELKhTSTLKQLMREFNTQLAQKEQELERT------V 2027
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAAL--KKEEKALLKQLAALERR-IAALARRIRALEQELAALEAELAELekeiaeL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 2028 QETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARR---YEEILDAREEEMTG------KVTDLQTQLEELQKK 2098
Cdd:COG4942   96 RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRlqyLKYLAPARREQAEElradlaELAALRAELEAERAE 175

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 20127150 2099 YQQRLEQEESTKDSVT--ILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKNACAATVGTP 2165
Cdd:COG4942  176 LEALLAELEEERAALEalKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1134-1365 1.25e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.25e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1134 SAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKS 1213
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1214 LEDKSLNLKSLLeeLASQLDSRCERTKALLEAKtnelvctSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQL 1293
Cdd:COG4942   99 LEAQKEELAELL--RALYRLGRQPPLALLLSPE-------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 20127150 1294 TQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEgllTEKEALQQEGGQQRQAASEKESCITQLKKELAE 1365
Cdd:COG4942  170 EAERAELEALLAELEEERAALEALKAERQKLLARLE---KELAELAAELAELQQEAEELEALIARLEAEAAA 238
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 693-907 1.29e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.29e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  693 EKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQ---ALEAELEEQRRHHQREVGSISEQQELTVRR 769
Cdd:COG4942   30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQelaALEAELAELEKEIAELRAELEAQKEELAEL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  770 AEKALK-DELSRLGALLDERD-EHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAgayEEQLAQMQQK 847
Cdd:COG4942  110 LRALYRlGRQPPLALLLSPEDfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL---EALLAELEEE 186

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  848 VLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQ 907
Cdd:COG4942  187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
964-1565 1.30e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.37  E-value: 1.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   964 KFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQfnaqilemaqansagisdtVSRLEENQRQQ 1043
Cdd:PRK03918  159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLRE-------------------INEISSELPEL 219

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1044 IESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKeqgLGELRQKVRIVQSEKEELTKEVARLKEaVSGQDVAL 1123
Cdd:PRK03918  220 REELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEK---IRELEERIEELKKEIEELEEKVKELKE-LKEKAEEY 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1124 AGLQGQLEQKSAVIVSLSERESQLQSQVEKLEAdlgcSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSC 1203
Cdd:PRK03918  296 IKLSEFYEEYLDELREIEKRLSRLEEEINGIEE----RIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKK 371

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1204 KSLHELSKKSLEDKSLNLKSLLEELasqldsrcERTKALLEAKTNElvctsrdkadaILARLSQCQRHTATVGEALLRRM 1283
Cdd:PRK03918  372 EELERLKKRLTGLTPEKLEKELEEL--------EKAKEEIEEEISK-----------ITARIGELKKEIKELKKAIEELK 432

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1284 GQVSELEAQLTQLTEEQRtlKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEscITQLKKEL 1363
Cdd:PRK03918  433 KAKGKCPVCGRELTEEHR--KELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKE--LAEQLKEL 508

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1364 AENINAVTLlrEELSEKKSEIASLSKQLSDLGAQLESSispSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEK 1443
Cdd:PRK03918  509 EEKLKKYNL--EELEKKAEEYEKLKEKLIKLKGEIKSL---KKELEKLEELKKKLAELEKKLDELEEELAELLKELEELG 583

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1444 MSALEQVDHWSNKFSEWKKKaQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRK-S 1522
Cdd:PRK03918  584 FESVEELEERLKELEPFYNE-YLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyE 662

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|...
gi 20127150  1523 KMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKN 1565
Cdd:PRK03918  663 ELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE 705
PRK12704 PRK12704
phosphodiesterase; Provisional
 1950-2081 1.32e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 47.08  E-value: 1.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1950 KQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNtQLAQKEQELERtvqe 2029
Cdd:PRK12704   26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEK-RLLQKEENLDR---- 100

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 20127150  2030 tidkaqevEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEM 2081
Cdd:PRK12704  101 --------KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQEL 144
mukB PRK04863
chromosome partition protein MukB;
656-921 1.43e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.26  E-value: 1.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   656 QQHQAAVEELREKYQQEKDAL--LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALR-------ARDQLAEE 726
Cdd:PRK04863  847 VELERALADHESQEQQQRSQLeqAKEGLSALNRLLPRLNLLADETLADRVEEIREQLDEAEEAKRfvqqhgnALAQLEPI 926

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   727 LSVLRGDadkmkqalEAELEEQRRHHQRevgsiSEQQELTVRRAEKALKDelsrlgalLDERDEHLRERQArVQDLEAhl 806
Cdd:PRK04863  927 VSVLQSD--------PEQFEQLKQDYQQ-----AQQTQRDAKQQAFALTE--------VVQRRAHFSYEDA-AEMLAK-- 982

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   807 qksAGELQQAL-AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEME------------------- 866
Cdd:PRK04863  983 ---NSDLNEKLrQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKqelqdlgvpadsgaeerar 1059

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 20127150   867 THKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 921
Cdd:PRK04863 1060 ARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNA 1114
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 319-1159 1.68e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 46.96  E-value: 1.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    319 KETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELhmaEKTKLITQLRDAKNLIEQLEQDKGMVITETKRQMLETLE 398
Cdd:TIGR00606  151 NNVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKAL---ETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQIT 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    399 LKEDEIAQLRSHIKQMTTQGEELREQKEKSE--RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQ 476
Cdd:TIGR00606  228 SKEAQLESSREIVKSYENELDPLKNRLKEIEhnLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLY 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    477 HELSRVRQEaasmakknSEEQVAALQKlHAEELASKEQELSRR---LEARERELQEQMRIALEKSR---SEYLKLTQEKE 550
Cdd:TIGR00606  308 HNHQRTVRE--------KERELVDCQR-ELEKLNKERRLLNQEkteLLVEQGRLQLQADRHQEHIRardSLIQSLATRLE 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    551 QQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTAL-- 628
Cdd:TIGR00606  379 LDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELkf 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    629 AEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQ---AHIQDMNEKTLEKLDKKQME 705
Cdd:TIGR00606  459 VIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRklrKLDQEMEQLNHHTTTRTQME 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    706 L--ESVSSELSEALRARDQLAEELSVLRGDADKMKQALE---------AELEEQRRHHQREVGSiSEQQELTVRRAEKAL 774
Cdd:TIGR00606  539 MltKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDwlhskskeiNQTRDRLAKLNKELAS-LEQNKNHINNELESK 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    775 KDELSRLGALLDERDEHlRERQARVQDLEAHLQKSAGELQQALAKLDLLHS--EQSAAREQA------------GAYEEQ 840
Cdd:TIGR00606  618 EEQLSSYEDKLFDVCGS-QDEESDLERLKEEIEKSSKQRAMLAGATAVYSQfiTQLTDENQSccpvcqrvfqteAELQEF 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    841 LAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQlQDSQLKNSTVEKEQARQ 920
Cdd:TIGR00606  697 ISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNR-DIQRLKNDIEEQETLLG 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    921 SLMEKENI---------ILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEK--RMEKIKQKAKEMQetkkKL 989
Cdd:TIGR00606  776 TIMPEEESakvcltdvtIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKqhELDTVVSKIELNR----KL 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    990 LDQEAKLKKELENTVLELsqkeKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESltgAHQRKLDDVIEAWEKKLSQQ 1069
Cdd:TIGR00606  852 IQDQQEQIQHLKSKTNEL----KSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREI---KDAKEQDSPLETFLEKDQQE 924

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1070 AAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARlkeavsgqdvalaGLQGQLEQKSAVIVSLSERESQLQS 1149
Cdd:TIGR00606  925 KEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQD-------------GKDDYLKQKETELNTVNAQLEECEK 991

                          890
                   ....*....|
gi 20127150   1150 QVEKLEADLG 1159
Cdd:TIGR00606  992 HQEKINEDMR 1001
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
431-904 1.77e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 1.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  431 AAFEELEKALSTAQKTEDAQRRMKMEMDEqmkaveraSEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELA 510
Cdd:COG4717   71 KELKELEEELKEAEEKEEEYAELQEELEE--------LEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELA 142

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  511 SKEQELsRRLEARERELQEQMRiALEKSRSEYlkltQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRIL 590
Cdd:COG4717  143 ELPERL-EELEERLEELRELEE-ELEELEAEL----AELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELE 216

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  591 ELETSLEkSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQ 670
Cdd:COG4717  217 EAQEELE-ELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAR 295

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  671 QEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSseLSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRR 750
Cdd:COG4717  296 EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLS--PEELLELLDRIEELQELLREAEELEEELQLEELEQEIA 373

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  751 HHQREVGSISEqqeltvrraekalkDELSRLGalldERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDL--LHSEQS 828
Cdd:COG4717  374 ALLAEAGVEDE--------------EELRAAL----EQAEEYQELKEELEELEEQLEELLGELEELLEALDEeeLEEELE 435

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 20127150  829 AAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQvvemethkkhvcEELDAQRAQVQQLERQRSELEEKVRSLAQLQ 904
Cdd:COG4717  436 ELEEELEELEEELEELREELAELEAELEQLEED------------GELAELLQELEELKAELRELAEEWAALKLAL 499
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 439-680 1.80e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.80e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  439 ALSTAQKTEDAQRRMKmEMDEQMKAVER---ASEEERLRLQHELSRVRQEAASMAKK--NSEEQVAALQKLHAEeLASKE 513
Cdd:COG4942   15 AAAQADAAAEAEAELE-QLQQEIAELEKelaALKKEEKALLKQLAALERRIAALARRirALEQELAALEAELAE-LEKEI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  514 QELSRRLEARERELQEQMRIALEKSRSEYLKLTqeKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELE 593
Cdd:COG4942   93 AELRAELEAQKEELAELLRALYRLGRQPPLALL--LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  594 TSLEKsLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSlwTERLQSLSQQHQAAVEELREKYQQEK 673
Cdd:COG4942  171 AERAE-LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE--AEELEALIARLEAEAAAAAERTPAAG 247


                 ....*..
gi 20127150  674 DALLKEK 680
Cdd:COG4942  248 FAALKGK 254
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 330-552 1.91e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  330 ALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDkgmvITETKRQmletLELKEDEIAQLRS 409
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR----IRALEQE----LAALEAELAELEK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  410 HIKQMTTQGEELREQKEKSERAAF----EELEKALSTAQKTEDAQRRMKMemdeqMKAVERASEEERLRLQHELSRVRQE 485
Cdd:COG4942   91 EIAELRAELEAQKEELAELLRALYrlgrQPPLALLLSPEDFLDAVRRLQY-----LKYLAPARREQAEELRADLAELAAL 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 20127150  486 AASMAKKNSE------EQVAALQKLhaEELASKEQELSRRLEARERELQEQMRiALEKSRSEYLKLTQEKEQQ 552
Cdd:COG4942  166 RAELEAERAEleallaELEEERAAL--EALKAERQKLLARLEKELAELAAELA-ELQQEAEELEALIARLEAE 235
Golgin_A5 pfam09787
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...
 710-870 2.15e-04

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.


Pssm-ID: 462900 [Multi-domain]  Cd Length: 305  Bit Score: 45.52  E-value: 2.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    710 SSELSEALRARDQLAEELSVLRGDAdkmkQALEAELEEQRRHHQREVGSISEQ------QELTVRRAEKALKDELSRLGA 783
Cdd:pfam09787   46 TLELEELRQERDLLREEIQKLRGQI----QQLRTELQELEAQQQEEAESSREQlqeleeQLATERSARREAEAELERLQE 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    784 LLDERDEHLRE----RQARVQDLEAHLQKSAGELQQAlaklDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLT 859
Cdd:pfam09787  122 ELRYLEEELRRskatLQSRIKDREAEIEKLRNQLTSK----SQSSSSQSELENRLHQLTETLIQKQTMLEALSTEKNSLV 197

                          170
                   ....*....|.
gi 20127150    860 KQVVEMETHKK 870
Cdd:pfam09787  198 LQLERMEQQIK 208
PLN02939 PLN02939
transferase, transferring glycosyl groups
 771-994 3.20e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.05  E-value: 3.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   771 EKALKDELSRLGALLDERDEHLR---ERQARVQDLEAHLQKSAGELQQALA-----------KLDLLHSEQSAAREQAGA 836
Cdd:PLN02939  165 KEALQGKINILEMRLSETDARIKlaaQEKIHVEILEEQLEKLRNELLIRGAteglcvhslskELDVLKEENMLLKDDIQF 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   837 YEEQLAQMQ---QKVLDLETEKSLLTKQVVEMEthkkhvCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSqlknSTV 913
Cdd:PLN02939  245 LKAELIEVAeteERVFKLEKERSLLDASLRELE------SKFIVAQEDVSKLSPLQYDCWWEKVENLQDLLDR----ATN 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   914 EKEQARQSLMEKENI--ILQMREEQAKE----------IEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKE 981
Cdd:PLN02939  315 QVEKAALVLDQNQDLrdKVDKLEASLKEanvskfssykVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSK 394

                         250
                  ....*....|....
gi 20127150   982 M-QETKKKLLDQEA 994
Cdd:PLN02939  395 LkEESKKRSLEHPA 408
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 704-814 4.05e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 45.84  E-value: 4.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  704 MELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEltvrrAEKALKDELSRLGA 783
Cdd:COG0542  404 MEIDSKPEELDELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWE-----AEKELIEEIQELKE 478

                         90       100       110
                 ....*....|....*....|....*....|.
gi 20127150  784 LLDERDEHLRERQARVQDLEAHLQKSAGELQ 814
Cdd:COG0542  479 ELEQRYGKIPELEKELAELEEELAELAPLLR 509
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1926-2117 4.16e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.39  E-value: 4.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1926 QSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTL 2005
Cdd:COG3206  204 KNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELS 283

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 2006 KQL------MREFNTQLAQKEQELERTVQETIDKAqEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEIldAREe 2079
Cdd:COG3206  284 ARYtpnhpdVIALRAQIAALRAQLQQEAQRILASL-EAELEALQAREASLQAQLAQLEARLAELPELEAELRRL--ERE- 359

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 20127150 2080 emtgkVTDLQTQLEELQKKYQQRLEQEESTKDSVTILE 2117
Cdd:COG3206  360 -----VEVARELYESLLQRLEEARLAEALTVGNVRVID 392
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1167-1407 4.42e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 4.42e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1167 SLQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckslhelskKSLEDKSLNLKSLLEELASQLDSRcERTKALLEAK 1246
Cdd:COG4942   24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQL-----------AALERRIAALARRIRALEQELAAL-EAELAELEKE 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1247 TNELVCTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLT---QLTEEQRTLKSSFQQVTNQLEEKEKQIKT 1323
Cdd:COG4942   92 IAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQylkYLAPARREQAEELRADLAELAALRAELEA 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1324 MKADIEGLLTEKEALQQEggqQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSIS 1403
Cdd:COG4942  172 ERAELEALLAELEEERAA---LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGF 248


                 ....
gi 20127150 1404 PSDK 1407
Cdd:COG4942  249 AALK 252
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
771-1238 4.43e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 4.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  771 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQ--KV 848
Cdd:COG4717   48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKllQL 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  849 LDLETEKSLLTKQVVEMETHKkhvcEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKeni 928
Cdd:COG4717  128 LPLYQELEALEAELAELPERL----EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE--- 200

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  929 ilqmREEQAKEIEILKQTLSSKEESISILHEEYETkfknqekrmekiKQKAKEMQETKKKLldQEAKLKKELENTVLELS 1008
Cdd:COG4717  201 ----LEELQQRLAELEEELEEAQEELEELEEELEQ------------LENELEAAALEERL--KEARLLLLIAAALLALL 262

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1009 QKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGL 1088
Cdd:COG4717  263 GLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLEL 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1089 GELRQKVRIVQSEKEELTKEvARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSL 1168
Cdd:COG4717  343 LDRIEELQELLREAEELEEE-LQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEEL 421

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 20127150 1169 QEELAELKLLADKSQLR--VSELTGQVQAAEKELQSCKslHELSKKSLEDKSLNLKSLLEELASQLDSRCER 1238
Cdd:COG4717  422 LEALDEEELEEELEELEeeLEELEEELEELREELAELE--AELEQLEEDGELAELLQELEELKAELRELAEE 491
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1223-1399 4.89e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 4.89e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1223 SLLEELASQLDS-RCERTKALLEAKTNELvctsRDKADAILARLSQCQRHTATVGEALLRRMGQVSELE-AQLTQLTEEQ 1300
Cdd:COG4913  272 AELEYLRAALRLwFAQRRLELLEAELEEL----RAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREI 347

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1301 RTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEScitQLKKELAENINAVTLLREELSEK 1380
Cdd:COG4913  348 ERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELE---ALEEALAEAEAALRDLRRELREL 424

                        170
                 ....*....|....*....
gi 20127150 1381 KSEIASLSKQLSDLGAQLE 1399
Cdd:COG4913  425 EAEIASLERRKSNIPARLL 443
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
1951-2152 7.06e-04

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 44.68  E-value: 7.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1951 QKLSKEVARLQKELRALR---REHQQELDILKRECEQEAEEKLKQ-EQEDLE-----LKHTSTLKQLMREFNTQLAQKEQ 2021
Cdd:COG0497  161 REAYRAWRALKKELEELRadeAERARELDLLRFQLEELEAAALQPgEEEELEeerrrLSNAEKLREALQEALEALSGGEG 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 2022 ELERTVQETIDKAQEVE---------AELLESHQEETQqlhrkiaekedDLRRTARRYEEILDAREEEMTgKVTDLQTQL 2092
Cdd:COG0497  241 GALDLLGQALRALERLAeydpslaelAERLESALIELE-----------EAASELRRYLDSLEFDPERLE-EVEERLALL 308

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 2093 EELQKKYQQRLEQeestkdsvtILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKR 2152
Cdd:COG0497  309 RRLARKYGVTVEE---------LLAYAEELRAELAELENSDERLEELEAELAEAEAELLE 359
PRK09039 PRK09039
peptidoglycan -binding protein;
1091-1232 7.55e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 44.19  E-value: 7.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1091 LRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQE 1170
Cdd:PRK09039   44 LSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQ 123

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 20127150  1171 ELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKslEDKSLNLKslLEELASQL 1232
Cdd:PRK09039  124 ELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEK--RDRESQAK--IADLGRRL 181
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 812-1030 7.85e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 7.85e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  812 ELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRS 891
Cdd:COG3883   17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  892 ELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKR 971
Cdd:COG3883   97 RSGGSVSYLDVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 20127150  972 MEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGIS 1030
Cdd:COG3883  177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1530-2072 8.93e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.65  E-value: 8.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1530 DLETALKTQTArvvELEDCVTQRKKEVESLNETlknynQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHV 1609
Cdd:PRK02224  210 GLESELAELDE---EIERYEEQREQARETRDEA-----DEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEV 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1610 SSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIrKQLLSQMEEKTQRyAKDTENRLS 1689
Cdd:PRK02224  282 RDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAA-QAHNEEAESLRED-ADDLEERAE 359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1690 ELSAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQeaPDSQDCTHKACKERLCMLQRRLSEKEKLLRR 1769
Cdd:PRK02224  360 ELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVD--LGNAEDFLEELREERDELREREAELEATLRT 437

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1770 LEQGEGEARPSQPEaqhralsGKldCTRARQ-LEDHVLIGCLPEELEEKMKCSLIVSQPmgEETGNNTGVKQNWASVVDS 1848
Cdd:PRK02224  438 ARERVEEAEALLEA-------GK--CPECGQpVEGSPHVETIEEDRERVEELEAELEDL--EEEVEEVEERLERAEDLVE 506

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1849 VQKTLQEKELTCQALEQRVKElesdlvrergaHRLEVEKLTLKYEKSQSSQQEMDGEnkCVEVLEDRPEENSQSHEIQSN 1928
Cdd:PRK02224  507 AEDRIERLEERREDLEELIAE-----------RRETIEEKRERAEELRERAAELEAE--AEEKREAAAEAEEEAEEAREE 573

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1929 VGTVDGLRSDLESKLTGAERDKQKLSK-EVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQ 2007
Cdd:PRK02224  574 VAELNSKLAELKERIESLERIRTLLAAiADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEARE 653

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 20127150  2008 LMREFNTQLAQKEQELERTVQETIDKAQEVEAelLESHQEETQQLHRKIAEKEDDLRRTARRYEE 2072
Cdd:PRK02224  654 DKERAEEYLEQVEEKLDELREERDDLQAEIGA--VENELEELEELRERREALENRVEALEALYDE 716
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 344-992 9.31e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.65  E-value: 9.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    344 DERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELRE 423
Cdd:TIGR00606  389 ERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEG 468

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    424 ------QKEKSERAAFEELEKA-----LSTAQKTEDAQRRMKMEMDEQMKAVERASEEERlrlQHELSRVRQEAASMAKK 492
Cdd:TIGR00606  469 ssdrilELDQELRKAERELSKAeknslTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLN---HHTTTRTQMEMLTKDKM 545

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    493 NSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESE 572
Cdd:TIGR00606  546 DKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYE 625

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    573 NKLQELGQeAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQ 652
Cdd:TIGR00606  626 DKLFDVCG-SQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKL 704

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    653 SLSQQHQAAVEELREKYQQEKDALLKEKESlfQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEEL----- 727
Cdd:TIGR00606  705 RLAPDKLKSTESELKKKEKRRDEMLGLAPG--RQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTImpeee 782

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    728 --SVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARvQDLEAH 805
Cdd:TIGR00606  783 saKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQ-QEQIQH 861

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    806 LQKSAGELQQALAKLdllhseqSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEE----LDAQRA 881
Cdd:TIGR00606  862 LKSKTNELKSEKLQI-------GTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEkeelISSKET 934

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    882 QVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEy 961
Cdd:TIGR00606  935 SNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQ- 1013

                          650       660       670
                   ....*....|....*....|....*....|.
gi 20127150    962 ETKFKNQEKRMeKIKQKAKEMQETKKKLLDQ 992
Cdd:TIGR00606 1014 ERWLQDNLTLR-KRENELKEVEEELKQHLKE 1043
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1476-2155 1.01e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.58  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1476 KDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV--RKSKMEKKECDLETALKTQTARVVELEDCVTQRK 1553
Cdd:pfam02463  233 KLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEeeKEKKLQEEELKLLAKEEEELKSELLKLERRKVDD 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1554 KEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSR 1633
Cdd:pfam02463  313 EEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1634 DGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQmEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1713
Cdd:pfam02463  393 KEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEI-LEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1714 SSPHPEVPAVSRSMQSVAASPEQEAPDSQDCThkACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKL 1793
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKES--KARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAV 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1794 DCTRAR-QLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELES 1872
Cdd:pfam02463  550 IVEVSAtADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGIL 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1873 DLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK 1952
Cdd:pfam02463  630 KDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREK 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1953 LSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNtqlaQKEQELERTVQETID 2032
Cdd:pfam02463  710 EELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELS----LKEKELAEEREKTEK 785

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   2033 KAQEVEAELLESHQEETqqlhrkIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDS 2112
Cdd:pfam02463  786 LKVEEEKEEKLKAQEEE------LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERL 859

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|...
gi 20127150   2113 VTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEK 2155
Cdd:pfam02463  860 EEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKEL 902
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 966-1202 1.02e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 1.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  966 KNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQfnaqiLEMAQANSAGISDTVSRLEENQRQQIE 1045
Cdd:COG4942   23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR-----IRALEQELAALEAELAELEKEIAELRA 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1046 SLTgAHQRKLDDVIEAWEKKLSQQAAELRdKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAG 1125
Cdd:COG4942   98 ELE-AQKEELAELLRALYRLGRQPPLALL-LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 20127150 1126 LQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGcslseklSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQS 1202
Cdd:COG4942  176 LEALLAELEEERAALEALKAERQKLLARLEKELA-------ELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1054-1714 1.08e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.58  E-value: 1.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1054 KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQK 1133
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1134 SAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKS 1213
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1214 LEDKSLNLKSLLEELASQLDSRCERTKALLEAKtnelvctsRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQL 1293
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAEEEEE--------EELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1294 TQLTEEQRTLKSSfQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLL 1373
Cdd:pfam02463  398 ELKSEEEKEAQLL-LELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1374 REELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLkVDALSKEKMSALEQVDHW 1453
Cdd:pfam02463  477 TQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVA-VENYKVAISTAVIVEVSA 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1454 SNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLET 1533
Cdd:pfam02463  556 TADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELT 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1534 ALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHsglVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLE 1613
Cdd:pfam02463  636 KLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELL---EIQELQEKAESELAKEEILRRQLEIKKKEQREKEEL 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1614 AELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSA 1693
Cdd:pfam02463  713 KKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEK 792

                          650       660
                   ....*....|....*....|.
gi 20127150   1694 QLKEREKQVHSLEDKLKNLES 1714
Cdd:pfam02463  793 EEKLKAQEEELRALEEELKEE 813
mukB PRK04863
chromosome partition protein MukB;
327-642 1.20e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.18  E-value: 1.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   327 EQCALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLitqlrdAKNLIEQLEQDKGMVITETKRQMLEtlelKEDEIAQ 406
Cdd:PRK04863  786 KRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFI------GSHLAVAFEADPEAELRQLNRRRVE----LERALAD 855

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   407 LRSHIKQMTTQGEELREQKEKSERAA--------------FEELEKALSTAQKTED--AQRRMKMEMDEQMKAVERASEE 470
Cdd:PRK04863  856 HESQEQQQRSQLEQAKEGLSALNRLLprlnlladetladrVEEIREQLDEAEEAKRfvQQHGNALAQLEPIVSVLQSDPE 935

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   471 --ERLRLQHELSRVRQEAASM---AKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKL 545
Cdd:PRK04863  936 qfEQLKQDYQQAQQTQRDAKQqafALTEVVQRRAHFSYEDAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQL 1015

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   546 TQEKeqQESLALEELELQKKAILTESENKLQELG-----QEAEAYRTRILELETSLEKSlQESKTQSEHLAVHLEAEKNK 620
Cdd:PRK04863 1016 AQYN--QVLASLKSSYDAKRQMLQELKQELQDLGvpadsGAEERARARRDELHARLSAN-RSRRNQLEKQLTFCEAEMDN 1092

                         330       340
                  ....*....|....*....|..
gi 20127150   621 HNKELTALAEQHRTEVEGLQQQ 642
Cdd:PRK04863 1093 LTKKLRKLERDYHEMREQVVNA 1114
mukB PRK04863
chromosome partition protein MukB;
713-1172 1.20e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.18  E-value: 1.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   713 LSEALRARDQLAEELSVLRGDADKMKQALEAEL----------EEQRRHHQREVGSIseQQELTvrRAEKALKDELSRLG 782
Cdd:PRK04863  235 MEAALRENRMTLEAIRVTQSDRDLFKHLITESTnyvaadymrhANERRVHLEEALEL--RRELY--TSRRQLAAEQYRLV 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   783 ALLDERDEHLRERQARVQDLEA---HL---------QKSAGELQQALAKLDLLHSEQSAAREQAgayeeqlaqmQQKVLD 850
Cdd:PRK04863  311 EMARELAELNEAESDLEQDYQAasdHLnlvqtalrqQEKIERYQADLEELEERLEEQNEVVEEA----------DEQQEE 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   851 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLeRQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIIL 930
Cdd:PRK04863  381 NEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQY-QQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELL 459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   931 QmreeqakeieiLKQTLSSKEESISILHEEYETKFK-NQEKRMEKIKQKAKEM---QETKKKLLDQEAKLKKELEntvlE 1006
Cdd:PRK04863  460 S-----------LEQKLSVAQAAHSQFEQAYQLVRKiAGEVSRSEAWDVARELlrrLREQRHLAEQLQQLRMRLS----E 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1007 LSQKEKQFNAQILEMAQANSagisdtVSRLEENQRQQIESLTGAHQRKLDDvieawekkLSQQAAELRDKHAEQMEEKEQ 1086
Cdd:PRK04863  525 LEQRLRQQQRAERLLAEFCK------RLGKNLDDEDELEQLQEELEARLES--------LSESVSEARERRMALRQQLEQ 590

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1087 gLGELRQKVRIVQSEKEELTKEVARLKEAV-----SGQDVaLAGLQGQLEQKSAVIVS---LSERESQLQSQVEKLEADL 1158
Cdd:PRK04863  591 -LQARIQRLAARAPAWLAAQDALARLREQSgeefeDSQDV-TEYMQQLLERERELTVErdeLAARKQALDEEIERLSQPG 668

                         490
                  ....*....|....
gi 20127150  1159 GCSLSEKLSLQEEL 1172
Cdd:PRK04863  669 GSEDPRLNALAERF 682
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
335-762 1.21e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  335 EKEALQEQLDERLQELEKMKELHMAEKTKLiTQLRDAKNLIEQLEQDKGMVITETKRqmLETLELKEDEIAQLRSHIKQM 414
Cdd:COG4717   92 ELQEELEELEEELEELEAELEELREELEKL-EKLLQLLPLYQELEALEAELAELPER--LEELEERLEELRELEEELEEL 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  415 TTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVerasEEERLRLQHELSRVRQEAASMAKKNS 494
Cdd:COG4717  169 EAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEA----QEELEELEEELEQLENELEAAALEER 244

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  495 EEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENK 574
Cdd:COG4717  245 LKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEEL 324

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  575 LQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALA-----EQHRTEVEGLQQQQDslWTE 649
Cdd:COG4717  325 LAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAgvedeEELRAALEQAEEYQE--LKE 402

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  650 RLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKT---LEKLDKKQMELESVSS--ELSEALRARDQLA 724
Cdd:COG4717  403 ELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELeelREELAELEAELEQLEEdgELAELLQELEELK 482

                        410       420       430
                 ....*....|....*....|....*....|....*...
gi 20127150  725 EELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQ 762
Cdd:COG4717  483 AELRELAEEWAALKLALELLEEAREEYREERLPPVLER 520
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1073-1316 1.21e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 1.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1073 LRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKeavsgQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVE 1152
Cdd:COG3206  162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFR-----QKNGLVDLSEEAKLLLQQLSELESQLAEARAELA 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1153 KLEADLgcslsEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQsckslhELSKKSLED--KSLNLKSLLEELAS 1230
Cdd:COG3206  237 EAEARL-----AALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELA------ELSARYTPNhpDVIALRAQIAALRA 305

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1231 QLDSRCERTKALLEAKTNELvctsRDKADAILARLSQcqrhtatvgeaLLRRMGQVSELEAQLTQLTEEQRTLKSSFQQV 1310
Cdd:COG3206  306 QLQQEAQRILASLEAELEAL----QAREASLQAQLAQ-----------LEARLAELPELEAELRRLEREVEVARELYESL 370


                 ....*.
gi 20127150 1311 TNQLEE 1316
Cdd:COG3206  371 LQRLEE 376
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
388-794 1.23e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  388 ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKE--KSERAAFEELEKALSTAQKTEDAQRRMKmEMDEQMKAVE 465
Cdd:COG4717   74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEelREELEKLEKLLQLLPLYQELEALEAELA-ELPERLEELE 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  466 RAsEEERLRLQHELSRVRQEAASMAKK--NSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQmRIALEKSRSEYL 543
Cdd:COG4717  153 ER-LEELRELEEELEELEAELAELQEEleELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEA-QEELEELEEELE 230

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  544 KLTQEKEQQESLALEELELQKKAIL------------------------------------------TESENKLQELGQE 581
Cdd:COG4717  231 QLENELEAAALEERLKEARLLLLIAaallallglggsllsliltiagvlflvlgllallflllarekASLGKEAEELQAL 310

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  582 AEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWT-------ERLQSL 654
Cdd:COG4717  311 PALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAeagvedeEELRAA 390

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  655 SQQHQAAvEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDA 734
Cdd:COG4717  391 LEQAEEY-QELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDG 469

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  735 DKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDElsRLGALLDERDEHLRE 794
Cdd:COG4717  470 ELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE--RLPPVLERASEYFSR 527
46 PHA02562
endonuclease subunit; Provisional
 845-1084 1.44e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.85  E-value: 1.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   845 QQKVLDLETEKSLLTKQVvemETHKKHVcEELDAQRAQ-VQQLERQRSELEEKVRSLAQLQDS---QLKNSTVEKEqarq 920
Cdd:PHA02562  180 NQQIQTLDMKIDHIQQQI---KTYNKNI-EEQRKKNGEnIARKQNKYDELVEEAKTIKAEIEEltdELLNLVMDIE---- 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   921 slmEKENIILQMREEQAKeieilkqtLSSKEESISILHEEYET---------KFKNQEKRMEKIKQKAKEMQETKKKLLD 991
Cdd:PHA02562  252 ---DPSAALNKLNTAAAK--------IKSKIEQFQKVIKMYEKggvcptctqQISEGPDRITKIKDKLKELQHSLEKLDT 320

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   992 QEAKLkKELENTVLELSQKEKQFNAQIlemaQANSAGISDTVSRLEENQRqQIESLTGAHQRKLDDVieaweKKLSQQAA 1071
Cdd:PHA02562  321 AIDEL-EEIMDEFNEQSKKLLELKNKI----STNKQSLITLVDKAKKVKA-AIEELQAEFVDNAEEL-----AKLQDELD 389

                         250
                  ....*....|...
gi 20127150  1072 ELRDKHAEQMEEK 1084
Cdd:PHA02562  390 KIVKTKSELVKEK 402
COG5022 COG5022
Myosin heavy chain [General function prediction only];
833-1384 1.44e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.91  E-value: 1.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  833 QAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQ----VQQLERQRSELEEKVRSLAQL--QDS 906
Cdd:COG5022  823 QKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQsaqrVELAERQLQELKIDVKSISSLklVNL 902

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  907 QLKNSTVEKEQARQSLMEKENIILQ---------------------MREEQAKEIEIL--KQTLSSKEESISILHEEYET 963
Cdd:COG5022  903 ELESEIIELKKSLSSDLIENLEFKTeliarlkkllnnidleegpsiEYVKLPELNKLHevESKLKETSEEYEDLLKKSTI 982

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  964 KFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK--KELENTVLELSQKEKQFNAQILEMAQANSagISDTVSRLEENQR 1041
Cdd:COG5022  983 LVREGNKANSELKNFKKELAELSKQYGALQESTKqlKELPVEVAELQSASKIISSESTELSILKP--LQKLKGLLLLENN 1060

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1042 QQIESLTGAHQRKLDDVI-----------EAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVA 1110
Cdd:COG5022 1061 QLQARYKALKLRRENSLLddkqlyqlestENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVN 1140

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1111 RLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEEL-AELKLLADKS------Q 1183
Cdd:COG5022 1141 TLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQSALYDEKSKLSSSEVNDLkNELIALFSKIfsgwprG 1220

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1184 LRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRC--ERTKALLEAKTNELVCTSRDKADAI 1261
Cdd:COG5022 1221 DKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSsyKLEEEVLPATINSLLQYINVGLFNA 1300

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1262 LArlSQCQRHTATVGEAL----------LRRMGqVSELEAQLTQLTEEQRTLKSSFQQVtNQLEEKEKQIKTMK-ADIEG 1330
Cdd:COG5022 1301 LR--TKASSLRWKSATEVnynseelddwCREFE-ISDVDEELEELIQAVKVLQLLKDDL-NKLDELLDACYSLNpAEIQN 1376

                        570       580       590       600       610
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 20127150 1331 LLTEKEALQQEGG--QQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEI 1384
Cdd:COG5022 1377 LKSRYDPADKENNlpKEILKKIEALLIKQELQLSLEGKDETEVHLSEIFSEEKSLI 1432
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1978-2060 1.48e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 43.66  E-value: 1.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1978 LKRECEQEAEE--KLKQEQEDLELKhtstLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRK 2055
Cdd:PRK00409  528 LERELEQKAEEaeALLKEAEKLKEE----LEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKELRQLQKGGYAS 603


                  ....*
gi 20127150  2056 IAEKE 2060
Cdd:PRK00409  604 VKAHE 608
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 705-941 1.54e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  705 ELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRRHHQREVGSISEQQELTvRRAEKALKDELSRLGAL 784
Cdd:COG4942   21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-ALERRIAALARRIRALEQELAAL-EAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  785 LDERDEHLRERQARVQDLEAH----LQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKslltk 860
Cdd:COG4942   99 LEAQKEELAELLRALYRLGRQpplaLLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER----- 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  861 qvvemethkkhvceelDAQRAQVQQLERQRSELEEKVRSLAQLQdSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEI 940
Cdd:COG4942  174 ----------------AELEALLAELEEERAALEALKAERQKLL-ARLEKELAELAAELAELQQEAEELEALIARLEAEA 236


                 .
gi 20127150  941 E 941
Cdd:COG4942  237 A 237
PRK01156 PRK01156
chromosome segregation protein; Provisional
 813-1400 2.07e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 43.35  E-value: 2.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   813 LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSE 892
Cdd:PRK01156  178 LRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESE 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   893 LEEKVRSLAQLQDSQLKNSTVEKEqarqsLMEKENIILQMREEQAKEIEILKQTLSSKEESISILheeyetkfKNQEKRM 972
Cdd:PRK01156  258 IKTAESDLSMELEKNNYYKELEER-----HMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNI--------DAEINKY 324

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   973 EKIKQKAKEMQETKKKLLDQEAKlKKELENTVLELSQKEKQFNAQILEMAQANsagisdtvsRLEENQRQQIESLTGAHQ 1052
Cdd:PRK01156  325 HAIIKKLSVLQKDYNDYIKKKSR-YDDLNNQILELEGYEMDYNSYLKSIESLK---------KKIEEYSKNIERMSAFIS 394

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1053 RKLdDVIEAWEKKLSQQAAELRDKhaeqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLkeavSGQDVA-LAGLQGQLE 1131
Cdd:PRK01156  395 EIL-KIQEIDPDAIKKELNEINVK----LQDISSKVSSLNQRIRALRENLDELSRNMEML----NGQSVCpVCGTTLGEE 465

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1132 QKSAVIVSLSERESQLQSQVEKLEADLGcSLSEKLSLQEELAElkLLADKSQLRVSELTGQVQAAEKELQSckslHELSK 1211
Cdd:PRK01156  466 KSNHIINHYNEKKSRLEEKIREIEIEVK-DIDEKIVDLKKRKE--YLESEEINKSINEYNKIESARADLED----IKIKI 538

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1212 KSLEDKSLNLKSLLEELAS----QLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTAtvgEALLRRMGQVS 1287
Cdd:PRK01156  539 NELKDKHDKYEEIKNRYKSlkleDLDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQ---EIEIGFPDDKS 615

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1288 ELEAQLTQLTEEQRTLKSSFqqvtNQLEEKEKQIKTMKADIEGL---LTEKEALQQEGGQQRQAASEKESCITQLKKELA 1364
Cdd:PRK01156  616 YIDKSIREIENEANNLNNKY----NEIQENKILIEKLRGKIDNYkkqIAEIDSIIPDLKEITSRINDIEDNLKKSRKALD 691

                         570       580       590
                  ....*....|....*....|....*....|....*.
gi 20127150  1365 ENINAVTLLREELSEKKSEIASLSKQLSDLGAQLES 1400
Cdd:PRK01156  692 DAKANRARLESTIEILRTRINELSDRINDINETLES 727
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 602-846 2.12e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 43.67  E-value: 2.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   602 ESKTQSEHLAVHLE---AEKNKHNKELTALAEQHRTEVEGlQQQQDSLWTERLQSLSQQHQAaveeLREKYQQEKDALLK 678
Cdd:NF012221 1539 ESSQQADAVSKHAKqddAAQNALADKERAEADRQRLEQEK-QQQLAAISGSQSQLESTDQNA----LETNGQAQRDAILE 1613

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   679 EKESlFQAHIQDMNeKTLEKLDkkqmELESVSSELSEalRARDQLAEE-LSVLRGDADKMKQALEAELEEQRRHH---QR 754
Cdd:NF012221 1614 ESRA-VTKELTTLA-QGLDALD----SQATYAGESGD--QWRNPFAGGlLDRVQEQLDDAKKISGKQLADAKQRHvdnQQ 1685

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   755 EVGSISEQQELTVRRAEKalkdelSRLGALLDERDEHlreRQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQA 834
Cdd:NF012221 1686 KVKDAVAKSEAGVAQGEQ------NQANAEQDIDDAK---ADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS 1756

                         250
                  ....*....|..
gi 20127150   835 GAyEEQLAQMQQ 846
Cdd:NF012221 1757 AA-ENKANQAQA 1767
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1932-2129 2.12e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 2.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1932 VDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREH------QQELDILKRECE--QEAEEKLKQEQEDLE-LKHT 2002
Cdd:COG4717   48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEeeyaelQEELEELEEELEelEAELEELREELEKLEkLLQL 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 2003 STLKQLMREFNTQLAQKEQELER------TVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDA 2076
Cdd:COG4717  128 LPLYQELEALEAELAELPERLEEleerleELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR 207

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 20127150 2077 REEemtgkvtdLQTQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLI 2129
Cdd:COG4717  208 LAE--------LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLL 252
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1459-2095 2.20e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.42  E-value: 2.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1459 EWKKKAQSRLAQHQSTIKDLQAQLDV-----KATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLET 1533
Cdd:TIGR00618  253 EEQLKKQQLLKQLRARIEELRAQEAVleetqERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAA 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1534 ALKTQ--TARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSS 1611
Cdd:TIGR00618  333 HVKQQssIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHT-LTQHIHTLQQQKTTLTQKLQSLCKELDILQREQAT 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1612 LEAELGTVKKELEHVNSSvksrDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSEL 1691
Cdd:TIGR00618  412 IDTRTSAFRDLQGQLAHA----KKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETR 487

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1692 SAQLKEREKQVHSLEDKLKNlESSPHPEVPAVSRSMQSVAASPEQEAPDsqdcTHKACKERLCMLQRRLSEKEKLLRRLE 1771
Cdd:TIGR00618  488 KKAVVLARLLELQEEPCPLC-GSCIHPNPARQDIDNPGPLTRRMQRGEQ----TYAQLETSEEDVYHQLTSERKQRASLK 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1772 QGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVL-IGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQ 1850
Cdd:TIGR00618  563 EQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQdLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELA 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1851 KTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDgenkcvevLEDRPEENSQSHEIQSNVG 1930
Cdd:TIGR00618  643 LKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYW--------KEMLAQCQTLLRELETHIE 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1931 TVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDIlkrECEQEAEEKLKQEQEDLELKHTSTLKQLMR 2010
Cdd:TIGR00618  715 EYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTE---AHFNNNEEVTAALQTGAELSHLAAEIQFFN 791

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   2011 EFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDARE--EEMTGKVTDL 2088
Cdd:TIGR00618  792 RLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKqlAQLTQEQAKI 871


                   ....*..
gi 20127150   2089 QTQLEEL 2095
Cdd:TIGR00618  872 IQLSDKL 878
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 333-1011 2.21e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.24  E-value: 2.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    333 LSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQ------DKGMVITETKRQMLETLELKEDEIAQ 406
Cdd:pfam01576   14 LQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEmrarlaARKQELEEILHELESRLEEEEERSQQ 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    407 LRSHIKQMTTQGEELREQKEKSERAAFE-ELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERL-RLQHELSRVRQ 484
Cdd:pfam01576   94 LQNEKKKMQQHIQDLEEQLDEEEAARQKlQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERIsEFTSNLAEEEE 173

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    485 EAASMAK-KNSEEQVAA--LQKLHAEELASKEQE-LSRRLEARERELQEQmrIALEKSRSEYLKLTQEKEQQESLALEEL 560
Cdd:pfam01576  174 KAKSLSKlKNKHEAMISdlEERLKKEEKGRQELEkAKRKLEGESTDLQEQ--IAELQAQIAELRAQLAKKEEELQAALAR 251

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    561 ELQKKAILTESENKLQELgqeaEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHrtEVEGLQ 640
Cdd:pfam01576  252 LEEETAQKNNALKKIREL----EAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTAAQQ--ELRSKR 325

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    641 QQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALlkeKESLFQAHIQDMNektlekLDKKQMELESVSSELSEALRAR 720
Cdd:pfam01576  326 EQEVTELKKALEEETRSHEAQLQEMRQKHTQALEEL---TEQLEQAKRNKAN------LEKAKQALESENAELQAELRTL 396

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    721 DQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISE-QQEL-TVRRAEKALKDELSRLGALLDERDEHLRERQAR 798
Cdd:pfam01576  397 QQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKlQSELeSVSSLLNEAEGKNIKLSKDVSSLESQLQDTQEL 476

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    799 VQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDA 878
Cdd:pfam01576  477 LQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEA 556

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    879 QR-------AQVQQLERQRSELEEKVRSLAQLQDSQLKN-STVEKEQAR--QSLMEKENIILQMREE------QAKEIEI 942
Cdd:pfam01576  557 LTqqleekaAAYDKLEKTKNRLQQELDDLLVDLDHQRQLvSNLEKKQKKfdQMLAEEKAISARYAEErdraeaEAREKET 636

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 20127150    943 LKQTLSSKEESISILHEEYETKFKNQEKRMEK-------IKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKE 1011
Cdd:pfam01576  637 RALSLARALEEALEAKEELERTNKQLRAEMEDlvsskddVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATE 712
PRK11281 PRK11281
mechanosensitive channel MscK;
1947-2150 2.55e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.98  E-value: 2.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1947 ERDKQKLSKEVARLQKELRalrrEHQQELDILKRECEQEAEEKL-KQEQEDLELKHTSTLKQL------MREFNTQLAQK 2019
Cdd:PRK11281   79 KEETEQLKQQLAQAPAKLR----QAQAELEALKDDNDEETRETLsTLSLRQLESRLAQTLDQLqnaqndLAEYNSQLVSL 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  2020 EQELERtVQETIDKA----QEVEAELLESHQEET-------QQLHRKIA--EKEDDLRRT----ARRYEEILDAREEEMT 2082
Cdd:PRK11281  155 QTQPER-AQAALYANsqrlQQIRNLLKGGKVGGKalrpsqrVLLQAEQAllNAQNDLQRKslegNTQLQDLLQKQRDYLT 233

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 20127150  2083 GKVTDLQTQLEELQKK-YQQRLEQEESTKDsvtilelQTQLAQKTTLISDSKLKEQELrEQVHNLEDRL 2150
Cdd:PRK11281  234 ARIQRLEHQLQLLQEAiNSKRLTLSEKTVQ-------EAQSQDEAARIQANPLVAQEL-EINLQLSQRL 294
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1917-2108 2.67e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1917 EENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAE-----EKLK 1991
Cdd:COG4942   38 ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEllralYRLG 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1992 QEQEDLELKHTSTLKQ------LMREFNTQLAQKEQELERTVQETIDKAQEVEAE------LLESHQEETQQLHRKIAEK 2059
Cdd:COG4942  118 RQPPLALLLSPEDFLDavrrlqYLKYLAPARREQAEELRADLAELAALRAELEAEraeleaLLAELEEERAALEALKAER 197

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 20127150 2060 EDDLRRTARRYEEiLDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEES 2108
Cdd:COG4942  198 QKLLARLEKELAE-LAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
PRK12704 PRK12704
phosphodiesterase; Provisional
 501-681 2.72e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.84  E-value: 2.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   501 LQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQeslaleelelqkkaiLTESENKLQELGQ 580
Cdd:PRK12704   25 RKKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKE---------------LRERRNELQKLEK 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   581 eaeayrtRILELETSLEKSLQESKTQSEhlavHLEAEKNKHNKELTALAEQhRTEVEGLQQQQDslwtERLQSLSQ--QH 658
Cdd:PRK12704   90 -------RLLQKEENLDRKLELLEKREE----ELEKKEKELEQKQQELEKK-EEELEELIEEQL----QELERISGltAE 153

                         170       180
                  ....*....|....*....|....*.
gi 20127150   659 QA---AVEELREKYQQEKDALLKEKE 681
Cdd:PRK12704  154 EAkeiLLEKVEEEARHEAAVLIKEIE 179
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
138-671 2.83e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 2.83e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  138 PSDMESEAEDAPWNSDGLSR-EQLLQRLRRMERSLS---SYRGKYSELVTAFQTLQREKKKLQGILSQSQDKSLR-RISE 212
Cdd:COG4913  220 EPDTFEAADALVEHFDDLERaHEALEDAREQIELLEpirELAERYAAARERLAELEYLRAALRLWFAQRRLELLEaELEE 299

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  213 LREELQMDQQAKKHLQDEFDACLEEKDQyisvlqtqvsLLKQRLQNGPMNVDapkplppgELQAEVHGDTEKmegvgepv 292
Cdd:COG4913  300 LRAELARLEAELERLEARLDALREELDE----------LEAQIRGNGGDRLE--------QLEREIERLERE-------- 353

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  293 gggtsaktLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAK 372
Cdd:COG4913  354 --------LEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELE 425

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  373 NLIEQLEQDKGMV---ITETKRQMLETLELKEDEI--------------------------------------AQLRSHI 411
Cdd:COG4913  426 AEIASLERRKSNIparLLALRDALAEALGLDEAELpfvgelievrpeeerwrgaiervlggfaltllvppehyAAALRWV 505

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  412 KQMTTQG----EELREQKEKSERAAFEE---LEKaLSTaqKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSR--- 481
Cdd:COG4913  506 NRLHLRGrlvyERVRTGLPDPERPRLDPdslAGK-LDF--KPHPFRAWLEAELGRRFDYVCVDSPEELRRHPRAITRagq 582

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  482 VRQEAASMAKK-------------NSEEQVAALQKlhaeELASKEQELsRRLEARERELQEQMRiALEKSRSEYLKLTQ- 547
Cdd:COG4913  583 VKGNGTRHEKDdrrrirsryvlgfDNRAKLAALEA----ELAELEEEL-AEAEERLEALEAELD-ALQERREALQRLAEy 656

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  548 ---EKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELE----------TSLEKSLQESKTQSEHLAVHL 614
Cdd:COG4913  657 swdEIDVASAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEeeldelkgeiGRLEKELEQAEEELDELQDRL 736

                        570       580       590       600       610
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 20127150  615 EAEKNKHNKELTALAEQHRTEV--EGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQ 671
Cdd:COG4913  737 EAAEDLARLELRALLEERFAAAlgDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
Gp58 pfam07902
gp58-like protein; Sequences found in this family are derived from a number of bacteriophage ...
 594-848 3.28e-03

gp58-like protein; Sequences found in this family are derived from a number of bacteriophage and prophage proteins. They are similar to gp58, a minor structural protein of Lactococcus delbrueckii bacteriophage LL-H.


Pssm-ID: 369586 [Multi-domain]  Cd Length: 594  Bit Score: 42.63  E-value: 3.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    594 TSLEKSLQESKTQSEHLAVHLEAEKNK-----------------HNKELTA----LAEQHRTEVEGLQQQQDSLWTERLQ 652
Cdd:pfam07902   74 TGLFKSLEEMLSQLKELNLELTDTKNSnlwskiklnnngmlreyHNDTIKTeiveSAEGIATRISEDTDKKLALINETIS 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    653 SLSQQHQAAVEELREKYQQEKDAL---LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEAlrARDQLAEELSV 729
Cdd:pfam07902  154 GIRREYQDADRQLSSSYQAGIEGLkatMASDKIGLQAEIQASAQGLSQRYDNEIRKLSAKITTTSSG--TTEAYESKLDD 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    730 LRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKAlkdeLSRLGALLDerdehlrERQARVQDLEahlqKS 809
Cdd:pfam07902  232 LRAEFTRSNQGMRTELESKISGLQSTQQSTAYQISQEISNREGA----VSRVQQDLD-------SYQRRLQDAE----KN 296

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 20127150    810 AGELQQALAKLdllhseQSAAREQAGAYEEQLAQMQ----QKV 848
Cdd:pfam07902  297 YSSLTQTVKGL------QSTVSDPNSKLESRITQLAglieQKV 333
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 157-552 3.41e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.80  E-value: 3.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    157 REQLLQRLRRMERSLSSY-RGKYSELVTAFQTLQREKKKLQGILSQ--SQDKSLRRISELREELQMDQQAKKHLQDEFDA 233
Cdd:pfam15921  424 RNMEVQRLEALLKAMKSEcQGQMERQMAAIQGKNESLEKVSSLTAQleSTKEMLRKVVEELTAKKMTLESSERTVSDLTA 503

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    234 CLEEKDQYISVLQTQVSLLKQRLQNGPMNVDAPKPlpPGELQAEVHGDTEKMEGVGEPVGggtsaKTLEMLQQRVkrqEN 313
Cdd:pfam15921  504 SLQEKERAIEATNAEITKLRSRVDLKLQELQHLKN--EGDHLRNVQTECEALKLQMAEKD-----KVIEILRQQI---EN 573

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    314 LLQrckeTIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELH-----------------MAEKTKLITQLRDAKNLIE 376
Cdd:pfam15921  574 MTQ----LVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKdkkdakirelearvsdlELEKVKLVNAGSERLRAVK 649

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    377 QLEQDKGMVITETKRQMLETLELKED-EIAQ--LRSHIKQMTTQGEELREQKeKSERAAFEELEKALSTAQKTEDAQRRM 453
Cdd:pfam15921  650 DIKQERDQLLNEVKTSRNELNSLSEDyEVLKrnFRNKSEEMETTTNKLKMQL-KSAQSELEQTRNTLKSMEGSDGHAMKV 728

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    454 KMEMDEQMKAVERASEEERLRLQhelsrVRQEAASMAKKNSEEQVAALQKLHAE--ELASKEQELSRRLE---ARERELQ 528
Cdd:pfam15921  729 AMGMQKQITAKRGQIDALQSKIQ-----FLEEAMTNANKEKHFLKEEKNKLSQElsTVATEKNKMAGELEvlrSQERRLK 803

                          410       420       430
                   ....*....|....*....|....*....|
gi 20127150    529 EQ---MRIALEKSRSEYLK---LTQEKEQQ 552
Cdd:pfam15921  804 EKvanMEVALDKASLQFAEcqdIIQRQEQE 833
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 773-1408 3.55e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.65  E-value: 3.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    773 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLdllhSEQSAAREQAGAYEEQLAQMQQKVLDLE 852
Cdd:TIGR00618  198 LLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYL----TQKREAQEEQLKKQQLLKQLRARIEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    853 TEKSLLTKQ--VVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLqdsqlknstvekeqarqsLMEKENIIL 930
Cdd:TIGR00618  274 AQEAVLEETqeRINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKL------------------LMKRAAHVK 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    931 QMREEQakEIEILKQTLSSKEESISILHEEyETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELEntvlelsqK 1010
Cdd:TIGR00618  336 QQSSIE--EQRRLLQTLHSQEIHIRDAHEV-ATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELD--------I 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1011 EKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGE 1090
Cdd:TIGR00618  405 LQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQ 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1091 LRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLqGQLEQKSAVIVSLSERESQLQSQVEKLEADLgcslsekLSLQE 1170
Cdd:TIGR00618  485 ETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDI-DNPGPLTRRMQRGEQTYAQLETSEEDVYHQL-------TSERK 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1171 ELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNEL 1250
Cdd:TIGR00618  557 QRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQ 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1251 VCTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQrTLKSSFQQVTNQLEEKEKQIKTMKADIEG 1330
Cdd:TIGR00618  637 CSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQ-SEKEQLTYWKEMLAQCQTLLRELETHIEE 715

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 20127150   1331 LLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKA 1408
Cdd:TIGR00618  716 YDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRL 793
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
957-1414 3.93e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 3.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  957 LHEEYETKfKNQEKRMEKIKQKAKEMQETKKKLLDQEAklkkELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRL 1036
Cdd:COG4913  240 AHEALEDA-REQIELLEPIRELAERYAAARERLAELEY----LRAALRLWFAQRRLELLEAELEELRAELARLEAELERL 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1037 EENQRQQIESLTGAHQRKLD---DVIEAWEKKLSQQAAEL--RDKHAEQMEEKEQGLG--------ELRQKVRIVQSEKE 1103
Cdd:COG4913  315 EARLDALREELDELEAQIRGnggDRLEQLEREIERLERELeeRERRRARLEALLAALGlplpasaeEFAALRAEAAALLE 394

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1104 ELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLgcslSEKLSLQEelAELKLLADKSQ 1183
Cdd:COG4913  395 ALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDAL----AEALGLDE--AELPFVGELIE 468

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1184 LRVSELTGQvQAAEKELQSCK------------------SLH----------ELSKKSLEDKSLNLKSLLEELASQLDSR 1235
Cdd:COG4913  469 VRPEEERWR-GAIERVLGGFAltllvppehyaaalrwvnRLHlrgrlvyervRTGLPDPERPRLDPDSLAGKLDFKPHPF 547

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1236 CERTKALLEAKTNELVCTS----RDKADAILArlsQCQ-RHTATVGEALLRRMG------------QVSELEAQLTQLTE 1298
Cdd:COG4913  548 RAWLEAELGRRFDYVCVDSpeelRRHPRAITR---AGQvKGNGTRHEKDDRRRIrsryvlgfdnraKLAALEAELAELEE 624

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1299 EQRTLKSSFQQVTNQLEEKEKQIKTMKA---------DIEGLLTEKEALQqeggQQRQAASEKESCITQLKKELAENINA 1369
Cdd:COG4913  625 ELAEAEERLEALEAELDALQERREALQRlaeyswdeiDVASAEREIAELE----AELERLDASSDDLAALEEQLEELEAE 700

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*
gi 20127150 1370 VTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISAL 1414
Cdd:COG4913  701 LEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL 745
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1570-1713 4.01e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.15  E-value: 4.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1570 RDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELgtvkkelehvnssvKSRDGELKALEDKLElesa 1649
Cdd:COG2433  390 LPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAEL--------------EEKDERIERLERELS---- 451

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 20127150 1650 akvELKRKAEQKIaairkqllsqmeeKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1713
Cdd:COG2433  452 ---EARSEERREI-------------RKDREISRLDREIERLERELEEERERIEELKRKLERLK 499
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1854-2167 4.08e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 4.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1854 QEKELTCQALEQRVKELESDLVRERgahrlEVEKLTLKYEKSQSSQQEMDGENKCVEvLEDRPEENSQ--SHEIQSNVGT 1931
Cdd:pfam17380  303 QEKEEKAREVERRRKLEEAEKARQA-----EMDRQAAIYAEQERMAMERERELERIR-QEERKRELERirQEEIAMEISR 376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1932 VDGLRSDLESKLTGAERDKQKLskEVARLQKelrALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMRE 2011
Cdd:pfam17380  377 MRELERLQMERQQKNERVRQEL--EAARKVK---ILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERV 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   2012 FNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEildaREEEMtgkvtdLQTQ 2091
Cdd:pfam17380  452 RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEE----RKRKL------LEKE 521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   2092 LEELQK---KYQQRLEQEESTKDSVTILE---LQTQLAQKTTLIS--DSKLKEQELREQVHNLEDRLKRYEKNACAATVG 2163
Cdd:pfam17380  522 MEERQKaiyEEERRREAEEERRKQQEMEErrrIQEQMRKATEERSrlEAMEREREMMRQIVESEKARAEYEATTPITTIK 601


                   ....
gi 20127150   2164 TPYK 2167
Cdd:pfam17380  602 PIYR 605
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1099-1323 4.16e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 4.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1099 QSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLL 1178
Cdd:COG4942   26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1179 AdKSQLRVSELTGQvQAAEKELQSCKSLHELSKKSLEDKSLN--LKSLLEELASQLDsRCERTKALLEAKTNELvctsRD 1256
Cdd:COG4942  106 L-AELLRALYRLGR-QPPLALLLSPEDFLDAVRRLQYLKYLApaRREQAEELRADLA-ELAALRAELEAERAEL----EA 178

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 20127150 1257 KADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKT 1323
Cdd:COG4942  179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1951-2143 4.26e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 4.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1951 QKLSKEVARLQKELRALRREH------QQELDILKRECEQEAE-EKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQEL 2023
Cdd:COG3206  185 PELRKELEEAEAALEEFRQKNglvdlsEEAKLLLQQLSELESQlAEARAELAEAEARLAALRAQLGSGPDALPELLQSPV 264

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 2024 ERTVQETIDKAQEVEAELLESHQEET---QQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQ 2100
Cdd:COG3206  265 IQQLRAQLAELEAELAELSARYTPNHpdvIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLA 344

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 20127150 2101 QRLEQEestkdsVTILELQTQLAQKTTLISD--SKLKEQELREQV 2143
Cdd:COG3206  345 ELPELE------AELRRLEREVEVARELYESllQRLEEARLAEAL 383
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 157-755 4.62e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.26  E-value: 4.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    157 REQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREKKKLQGILSQSqdkslrriselrEELQMDQQAKKHLQDEFDACLE 236
Cdd:TIGR00618  309 AQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQE------------IHIRDAHEVATSIREISCQQHT 376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    237 EKdQYISVLQTQVSLLKQRLQNGPMNVDapkplppgELQAEVHGDTEKMEGVGEPVGGGTSAKTLEMLQQRVKRQENLLQ 316
Cdd:TIGR00618  377 LT-QHIHTLQQQKTTLTQKLQSLCKELD--------ILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAI 447

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    317 RCKETIGSHKEqcalllSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVI-TETKRQMLE 395
Cdd:TIGR00618  448 TCTAQCEKLEK------IHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIhPNPARQDID 521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    396 TLELKEDEIAQLRSHIKQMTTQGEELREQKEkSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEeerlRL 475
Cdd:TIGR00618  522 NPGPLTRRMQRGEQTYAQLETSEEDVYHQLT-SERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITV----RL 596

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    476 QHELsrvrqeaasmaKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESL 555
Cdd:TIGR00618  597 QDLT-----------EKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHAL 665

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    556 ALEELELQKKAILTESENKLQELGQEAEAYR---TRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAE-- 630
Cdd:TIGR00618  666 SIRVLPKELLASRQLALQKMQSEKEQLTYWKemlAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQsl 745

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    631 -----------QHRTEVEGLQQQQDSLWTERLQSLsqQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKL 699
Cdd:TIGR00618  746 kelmhqartvlKARTEAHFNNNEEVTAALQTGAEL--SHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQC 823

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 20127150    700 DKKQMELESVSSELSEalraRDQLAEELSVLRGDADKMKQALEAELEEQRRHHQRE 755
Cdd:TIGR00618  824 ETLVQEEEQFLSRLEE----KSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLS 875
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
698-823 4.98e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.57  E-value: 4.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  698 KLDKKQMELESVSSELsEALRARDQLAEELSVLRGDADKMKQALE-AELEEQRRHHQREVGSISEQQELTVRRAEKALKD 776
Cdd:COG1566   84 ALAQAEAQLAAAEAQL-ARLEAELGAEAEIAAAEAQLAAAQAQLDlAQRELERYQALYKKGAVSQQELDEARAALDAAQA 162

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 20127150  777 ELSRLGALLDERDEHLRErQARVQDLEAHLQKSAGELQQALAKLDLL 823
Cdd:COG1566  163 QLEAAQAQLAQAQAGLRE-EEELAAAQAQVAQAEAALAQAELNLART 208
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
299-742 5.02e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 5.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   299 KTLEMLQQRVKRQENL---------LQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKElhmaektklitQLR 369
Cdd:PRK03918  273 KEIEELEEKVKELKELkekaeeyikLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEE-----------RLE 341

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   370 DAKNLIEQLEQDKGmvITETKRQMLETLELKEDEIAQLRSHIKQMTTqgEELREQKEKSERAAfEELEKALStaqKTEDA 449
Cdd:PRK03918  342 ELKKKLKELEKRLE--ELEERHELYEEAKAKKEELERLKKRLTGLTP--EKLEKELEELEKAK-EEIEEEIS---KITAR 413

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   450 QRRMKMEMDEQMKAVER--------------ASEEERLRL----QHELSRVRQEAASMAKKNSE---EQVAALQKLHAEE 508
Cdd:PRK03918  414 IGELKKEIKELKKAIEElkkakgkcpvcgreLTEEHRKELleeyTAELKRIEKELKEIEEKERKlrkELRELEKVLKKES 493

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   509 LASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQE-----KEQQESLALEELELQKKAILTESENKLQELGQEAE 583
Cdd:PRK03918  494 ELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKliklkGEIKSLKKELEKLEELKKKLAELEKKLDELEEELA 573

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   584 AYRTRILELETSLEKSLQESktqsehlavhLEAEKNKHNKELTALAEQHRTEVEglqqqqdslwTERLQSLSQQHQAAVE 663
Cdd:PRK03918  574 ELLKELEELGFESVEELEER----------LKELEPFYNEYLELKDAEKELERE----------EKELKKLEEELDKAFE 633

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 20127150   664 ELREKyQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALE 742
Cdd:PRK03918  634 ELAET-EKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKK 711
mukB PRK04863
chromosome partition protein MukB;
469-1213 5.02e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 5.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   469 EEERLRLQHELSRVRQEAASmakknSEEQVAALQKLHaEELASKEQELSRRLEARERELQ----------EQMRI--ALE 536
Cdd:PRK04863  278 ANERRVHLEEALELRRELYT-----SRRQLAAEQYRL-VEMARELAELNEAESDLEQDYQaasdhlnlvqTALRQqeKIE 351

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   537 KSRSEYLKLTQEKEQQESLALEELELQkkailTESENKLQELGQEAEAYRTRILELETSLEksLQESKTQSEHLAVHLEA 616
Cdd:PRK04863  352 RYQADLEELEERLEEQNEVVEEADEQQ-----EENEARAEAAEEEVDELKSQLADYQQALD--VQQTRAIQYQQAVQALE 424

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   617 EKNKHNKELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQ---HQAAVEELREKYQ---------QEKDALLKEKESLF 684
Cdd:PRK04863  425 RAKQLCGLPDLTADNAEDWLEEFQAKEQEA-TEELLSLEQKlsvAQAAHSQFEQAYQlvrkiagevSRSEAWDVARELLR 503

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   685 QAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMkQALEAELEEQRRHHQREVGSISEQQE 764
Cdd:PRK04863  504 RLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDEL-EQLQEELEARLESLSESVSEARERRM 582

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   765 lTVRRAEKALKDELSRLGAL------LDERDEHLRE----RQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQA 834
Cdd:PRK04863  583 -ALRQQLEQLQARIQRLAARapawlaAQDALARLREqsgeEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEI 661

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   835 -------GAYEEQLAQMQQK---------------------------------VLDLETEKSLLTKQ------------- 861
Cdd:PRK04863  662 erlsqpgGSEDPRLNALAERfggvllseiyddvsledapyfsalygparhaivVPDLSDAAEQLAGLedcpedlyliegd 741

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   862 -------VVEMETHKKHVCEEL-DAQ--------------RAQVQQLERQRSELEEKVRSLAQLQ-DSQLKNSTVEK--- 915
Cdd:PRK04863  742 pdsfddsVFSVEELEKAVVVKIaDRQwrysrfpevplfgrAAREKRIEQLRAEREELAERYATLSfDVQKLQRLHQAfsr 821

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   916 ------------------EQARQSLMEKENIILQMRE------EQAKEIEILKQTLSSKEESISILHEEyetkfkNQEKR 971
Cdd:PRK04863  822 figshlavafeadpeaelRQLNRRRVELERALADHESqeqqqrSQLEQAKEGLSALNRLLPRLNLLADE------TLADR 895

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   972 MEKIKQKAKEMQETkKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgisdtvsrlEENQRQQIESLTGAH 1051
Cdd:PRK04863  896 VEEIREQLDEAEEA-KRFVQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQT---------QRDAKQQAFALTEVV 965

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1052 QRKLDDVIEAWEKKLSqQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLE 1131
Cdd:PRK04863  966 QRRAHFSYEDAAEMLA-KNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQ 1044

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1132 QKSAVIVslSERESQLQSQVEKLEADLGCSLSEKLSLQEELAelklladKSQLRVSELTGQVQAAEKELQSCKSLHELSK 1211
Cdd:PRK04863 1045 DLGVPAD--SGAEERARARRDELHARLSANRSRRNQLEKQLT-------FCEAEMDNLTKKLRKLERDYHEMREQVVNAK 1115


                  ..
gi 20127150  1212 KS 1213
Cdd:PRK04863 1116 AG 1117
PLN02939 PLN02939
transferase, transferring glycosyl groups
 904-1227 5.07e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 42.20  E-value: 5.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   904 QDSQLKN----STVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILH-EEYETKFKNQEKRMEKIKQK 978
Cdd:PLN02939   71 ENGQLENtslrTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDGEQLSDFQlEDLVGMIQNAEKNILLLNQA 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   979 AKEMQETKKKLLDQEAKLKKELENTVLELSQK--------EKQFNAQIL---------EMAQANSAGISDTVSRLEENQR 1041
Cdd:PLN02939  151 RLQALEDLEKILTEKEALQGKINILEMRLSETdariklaaQEKIHVEILeeqleklrnELLIRGATEGLCVHSLSKELDV 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1042 QQIESLTgahqrkLDDVIEAWEKKLS--QQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEEL-TKEVARLKEAVSG 1118
Cdd:PLN02939  231 LKEENML------LKDDIQFLKAELIevAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLsPLQYDCWWEKVEN 304

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1119 QDVALAGLQGQLEQKSAVIvslsERESQLQSQVEKLEADLGCSLSEKLSLQeelaelklLADKSQLRVSELTGQVQAAEK 1198
Cdd:PLN02939  305 LQDLLDRATNQVEKAALVL----DQNQDLRDKVDKLEASLKEANVSKFSSY--------KVELLQQKLKLLEERLQASDH 372

                         330       340
                  ....*....|....*....|....*....
gi 20127150  1199 ELQSCKSLHELSKKSLEDkslNLKSLLEE 1227
Cdd:PLN02939  373 EIHSYIQLYQESIKEFQD---TLSKLKEE 398
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 840-1020 5.31e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.68  E-value: 5.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  840 QLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNSTVEKEQA 918
Cdd:COG1579   11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVeARIKKYEEQLGNVRNNKE 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  919 RQSLMekeniilqmreeqaKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKK 998
Cdd:COG1579   91 YEALQ--------------KEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA 156

                        170       180
                 ....*....|....*....|..
gi 20127150  999 ELENTVLELSQKEKQFNAQILE 1020
Cdd:COG1579  157 ELEELEAEREELAAKIPPELLA 178
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 337-716 6.25e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 41.96  E-value: 6.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   337 EALQEQL---DERLQELEKMKELHMA--EKTKLITQLRDAKNL-------------IEQLEQDkgmvITETKRQMLET-- 396
Cdd:PRK10929   48 EALQSALnwlEERKGSLERAKQYQQVidNFPKLSAELRQQLNNerdeprsvppnmsTDALEQE----ILQVSSQLLEKsr 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   397 -LELKEDEIAQLRSHIKQMTTQGEELREQKEKSER------AAFEELEKALSTAQKTEDAQRRMKMEMDE--QMKAVERa 467
Cdd:PRK10929  124 qAQQEQDRAREISDSLSQLPQQQTEARRQLNEIERrlqtlgTPNTPLAQAQLTALQAESAALKALVDELElaQLSANNR- 202

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   468 seeerlrlqHELSRVRQEaasMAKKNSEEQVAALQKLHAEELASKEQELSRRLEAREReLQEQMRiALEKSRSEYLK--- 544
Cdd:PRK10929  203 ---------QELARLRSE---LAKKRSQQLDAYLQALRNQLNSQRQREAERALESTEL-LAEQSG-DLPKSIVAQFKinr 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   545 -LTQEKEQQESLALEELELQKKAIltesenklqelgqeaeayrTRILELETSLeKSLQEsktQSEHLAVHleaeknkhnk 623
Cdd:PRK10929  269 eLSQALNQQAQRMDLIASQQRQAA-------------------SQTLQVRQAL-NTLRE---QSQWLGVS---------- 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   624 elTALAEQHRTEVEGL-----QQQQDS----LWTERL---------QSLSQQHQAAVEELREKYQQEKDALLKEKESLFQ 685
Cdd:PRK10929  316 --NALGEALRAQVARLpempkPQQLDTemaqLRVQRLryedllnkqPQLRQIRQADGQPLTAEQNRILDAQLRTQRELLN 393

                         410       420       430
                  ....*....|....*....|....*....|...
gi 20127150   686 AHIQDMNEKTLE--KLDKKQMELESVSSELSEA 716
Cdd:PRK10929  394 SLLSGGDTLILEltKLKVANSQLEDALKEVNEA 426
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 970-1585 6.40e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 41.66  E-value: 6.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    970 KRMEKIKQKAKEMQETKKKLLDQEAKLKKE-LENTVLELSQKEKQFNAQILEMAQAnsaGISDTVSRLEENQRQQIESLT 1048
Cdd:pfam07111   70 RQLQELRRLEEEVRLLRETSLQQKMRLEAQaMELDALAVAEKAGQAEAEGLRAALA---GAEMVRKNLEEGSQRELEEIQ 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1049 GAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQkVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQG 1128
Cdd:pfam07111  147 RLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLNSLETKRAGEAKQ-LAEAQKEAELLRKQLSKTQEELEAQVTLVESLRK 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1129 QLEQKSAVIVSLSERESQLQSQVEKLEadlgcslseklSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSckslhe 1208
Cdd:pfam07111  226 YVGEQVPPEVHSQTWELERQELLDTMQ-----------HLQEDRADLQATVELLQVRVQSLTHMLALQEEELTR------ 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1209 lskksledKSLNLKSLLEELASqldsrcertkalleaKTNELVCTSRDKADAILARL-SQCQRHTATVGEAllrrMGQVS 1287
Cdd:pfam07111  289 --------KIQPSDSLEPEFPK---------------KCRSLLNRWREKVFALMVQLkAQDLEHRDSVKQL----RGQVA 341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1288 ELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQ-------AASEKESCITQLK 1360
Cdd:pfam07111  342 ELQEQVTSQSQEQAILQRALQDKAAEVEVERMSAKGLQMELSRAQEARRRQQQQTASAEEqlkfvvnAMSSTQIWLETTM 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1361 KELAENINAVTLLREELSEKKSEIAS----LSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKV 1436
Cdd:pfam07111  422 TRVEQAVARIPSLSNRLSYAVRKVHTikglMARKVALAQLRQESCPPPPPAPPVDADLSLELEQLREERNRLDAELQLSA 501

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1437 DALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKF----EC 1512
Cdd:pfam07111  502 HLIQQEVGRAREQGEAERQQLSEVAQQLEQELQRAQESLASVGQQLEVARQGQQESTEEAASLRQELTQQQEIYgqalQE 581

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 20127150   1513 LKGEMEVR-KSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLE 1585
Cdd:pfam07111  582 KVAEVETRlREQLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKERNQELRRLQDEARKEEGQRLARRVQELE 655
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 296-502 6.57e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 6.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  296 TSAKTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMK----ELHMAEKTKLITQLRDA 371
Cdd:COG4942   52 ALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLralyRLGRQPPLALLLSPEDF 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  372 KNLIEQLEQDKGmvITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERaafeELEKALSTAQKTEDAQR 451
Cdd:COG4942  132 LDAVRRLQYLKY--LAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERA----ALEALKAERQKLLARLE 205

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 20127150  452 RMKMEMDEQMKAVERASEeerlRLQHELSRVRQEAASMAKKNSEEQVAALQ 502
Cdd:COG4942  206 KELAELAAELAELQQEAE----ELEALIARLEAEAAAAAERTPAAGFAALK 252
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 925-1147 7.10e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.74  E-value: 7.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   925 KENIIlqmreEQAKEIeilkqtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTV 1004
Cdd:PRK00409  500 PENII-----EEAKKL------IGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLL 568

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1005 LELSQKEKqfnaQILEMAQANSAGIsdtVSRLEENQRQQIESLtgahqrKLDDVIEAweKKLSQQAAELRDKHAEQMEEK 1084
Cdd:PRK00409  569 EEAEKEAQ----QAIKEAKKEADEI---IKELRQLQKGGYASV------KAHELIEA--RKRLNKANEKKEKKKKKQKEK 633

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 20127150  1085 EQGL--GE------LRQKVRIVQ-SEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQL 1147
Cdd:PRK00409  634 QEELkvGDevkylsLGQKGEVLSiPDDKEAIVQAGIMKMKVPLSDLEKIQKPKKKKKKKPKTVKPKPRTVSL 705
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1933-2043 7.78e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 40.77  E-value: 7.78e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150    1933 DGLRSDLESKLTGAERDKQKLSKE-------VARLQKELRALRREHQQeLDILKRECEQEAEEKLKQEQEDLElkhtSTL 2005
Cdd:smart00787  143 EGLKEGLDENLEGLKEDYKLLMKElellnsiKPKLRDRKDALEEELRQ-LKQLEDELEDCDPTELDRAKEKLK----KLL 217

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|
gi 20127150    2006 KQLMREFN--TQLAQKEQELERTVQETIDKAQEVEAELLE 2043
Cdd:smart00787  218 QEIMIKVKklEELEEELQELESKIEDLTNKKSELNTEIAE 257
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1079-1698 7.98e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.59  E-value: 7.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1079 EQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEA-- 1156
Cdd:PRK03918  158 DDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEElk 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1157 -DLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLE-----DKSLNLKSLLEELAS 1230
Cdd:PRK03918  238 eEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKlsefyEEYLDELREIEKRLS 317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1231 QLDSRCERTKALLE--AKTNELVCTSRDKADAILARLSQCQRHTATVGEAlLRRMGQVSELEAQLTQLTEEqrtlkssfq 1308
Cdd:PRK03918  318 RLEEEINGIEERIKelEEKEERLEELKKKLKELEKRLEELEERHELYEEA-KAKKEELERLKKRLTGLTPE--------- 387

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1309 QVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKES-------CITQLKKELAENINAVtlLREELSEKK 1381
Cdd:PRK03918  388 KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvCGRELTEEHRKELLEE--YTAELKRIE 465

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1382 SEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEkmsaLEQVDHWSNKFsewk 1461
Cdd:PRK03918  466 KELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEE----YEKLKEKLIKL---- 537

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1462 KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQIC-LLKEDLDRQNKKFECLKGEMEvRKSKMEKKECDLETALKTQTA 1540
Cdd:PRK03918  538 KGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAeLLKELEELGFESVEELEERLK-ELEPFYNEYLELKDAEKELER 616

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1541 RVVELEDCVTQRKKEVESLNETLKNYNQQRdtehsglvqrlQHLEELGEE-KDNKVREAEETVLRLREHVSSLEAELGTV 1619
Cdd:PRK03918  617 EEKELKKLEEELDKAFEELAETEKRLEELR-----------KELEELEKKySEEEYEELREEYLELSRELAGLRAELEEL 685

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 20127150  1620 KKELEHVNSSVKSRDGELKALEDKLElesaaKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKER 1698
Cdd:PRK03918  686 EKRREEIKKTLEKLKEELEEREKAKK-----ELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEELTEG 759
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 366-477 8.17e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.22  E-value: 8.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  366 TQLRDAKNLIEQLEQDKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGE-------ELREQKEKSERAAFE--EL 436
Cdd:COG0542  411 EELDELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWEaekelieEIQELKEELEQRYGKipEL 490

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 20127150  437 EKALSTAQKTEDAQRRM-KMEMDEQMKA----------VERASEEERLRLQH 477
Cdd:COG0542  491 EKELAELEEELAELAPLlREEVTEEDIAevvsrwtgipVGKLLEGEREKLLN 542
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 886-1114 8.22e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.45  E-value: 8.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   886 LERQRSELEEKVRSL--AQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYET 963
Cdd:PRK05771   14 LKSYKDEVLEALHELgvVHIEDLKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEE 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   964 KFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKeLENTVLELsqkekqfnaqILEMAQANSAGISDTVSRLEENQRQQ 1043
Cdd:PRK05771   94 ELEKIEKEIKELEEEISELENEIKELEQEIERLEP-WGNFDLDL----------SLLLGFKYVSVFVGTVPEDKLEELKL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150  1044 IESLTGA---HQRKLDDVIEAW-EKKLSQQAAELRDKH-AEQMEEKEQG-----LGELRQKVRIVQSEKEELTKEVARLK 1113
Cdd:PRK05771  163 ESDVENVeyiSTDKGYVYVVVVvLKELSDEVEEELKKLgFERLELEEEGtpselIREIKEELEEIEKERESLLEELKELA 242


                  .
gi 20127150  1114 E 1114
Cdd:PRK05771  243 K 243
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1614-1970 9.60e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.21  E-value: 9.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1614 AELGTVKKELEHVNSSVKSRDGELKALEDKLE--LESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSEL 1691
Cdd:TIGR02169  177 EELEEVEENIERLDLIIDEKRQQLERLRREREkaERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1692 SAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDcTHKACKERLCMLQRRLSEKEKLLRRLE 1771
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLER-SIAEKERELEDAEERLAKLEAEIDKLL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1772 qgegearpsqpeAQHRALSGKLDCTRARQLEdhvligcLPEELEEKmkcslivsqpmgeetgnntgvkqnwASVVDSVQK 1851
Cdd:TIGR02169  336 ------------AEIEELEREIEEERKRRDK-------LTEEYAEL-------------------------KEELEDLRA 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150   1852 TLQEKELTCQALEQRVKELE---SDLVRERGAHRLEVEKLtlKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSN 1928
Cdd:TIGR02169  372 ELEEVDKEFAETRDELKDYReklEKLKREINELKRELDRL--QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE 449

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 20127150   1929 VGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRRE 1970
Cdd:TIGR02169  450 IKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1285-1400 9.86e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 9.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20127150 1285 QVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKAD--IEGLLTEKEALQQEGGQQRQAASEKESCITQLKKE 1362
Cdd:COG3206  220 QLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSpvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQ 299

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 20127150 1363 LAENINAV-TLLREELSEKKSEIASLSKQLSDLGAQLES 1400
Cdd:COG3206  300 IAALRAQLqQEAQRILASLEAELEALQAREASLQAQLAQ 338
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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