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Conserved domains on  [gi|157266319|ref|NP_061233|]
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carbohydrate sulfotransferase 2 [Mus musculus]

Protein Classification

sulfotransferase family protein( domain architecture ID 229543)

sulfotransferase family protein may utilize 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to its substrate(s)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sulfotransfer_1 super family cl21551
Sulfotransferase domain;
311-507 3.27e-12

Sulfotransferase domain;


The actual alignment was detected with superfamily member pfam00685:

Pssm-ID: 473908 [Multi-domain]  Cd Length: 253  Bit Score: 66.60  E-value: 3.27e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157266319  311 VAVLAPLLKDPalDLKVIHLVRDPRAVASSRIrsrhglireslQVVRSRDPRahrmpfleaagHKLGAKKEGMggpadyH 390
Cdd:pfam00685  81 LHLLPKSLWDP--NAKIIYLVRNPKDVAVSYY-----------HFFRMAKLL-----------KAPGTPFEFV------E 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157266319  391 ALGAMEVICNSMAKTLQTALQPpdWLQGHYLVVRYEDLVGDPVKTLRRVYDFVGLLVSPEM-----EQFALNMTSG---S 462
Cdd:pfam00685 131 DFLNGKVNCGSYFDHVKGWWKL--RPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLTEEEldkivKHLSFENMKGnpcL 208

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 157266319  463 GSSSKPFVVSARNATQAANAWRTALTFQQIKQVEEFCYQPMAVLG 507
Cdd:pfam00685 209 NYSKLPKEVSPFFRKGLVGDWKNYFTPEQAEKFDEIYQEKMKGTG 253
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
311-507 3.27e-12

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 66.60  E-value: 3.27e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157266319  311 VAVLAPLLKDPalDLKVIHLVRDPRAVASSRIrsrhglireslQVVRSRDPRahrmpfleaagHKLGAKKEGMggpadyH 390
Cdd:pfam00685  81 LHLLPKSLWDP--NAKIIYLVRNPKDVAVSYY-----------HFFRMAKLL-----------KAPGTPFEFV------E 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157266319  391 ALGAMEVICNSMAKTLQTALQPpdWLQGHYLVVRYEDLVGDPVKTLRRVYDFVGLLVSPEM-----EQFALNMTSG---S 462
Cdd:pfam00685 131 DFLNGKVNCGSYFDHVKGWWKL--RPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLTEEEldkivKHLSFENMKGnpcL 208

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 157266319  463 GSSSKPFVVSARNATQAANAWRTALTFQQIKQVEEFCYQPMAVLG 507
Cdd:pfam00685 209 NYSKLPKEVSPFFRKGLVGDWKNYFTPEQAEKFDEIYQEKMKGTG 253
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
311-507 3.27e-12

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 66.60  E-value: 3.27e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157266319  311 VAVLAPLLKDPalDLKVIHLVRDPRAVASSRIrsrhglireslQVVRSRDPRahrmpfleaagHKLGAKKEGMggpadyH 390
Cdd:pfam00685  81 LHLLPKSLWDP--NAKIIYLVRNPKDVAVSYY-----------HFFRMAKLL-----------KAPGTPFEFV------E 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157266319  391 ALGAMEVICNSMAKTLQTALQPpdWLQGHYLVVRYEDLVGDPVKTLRRVYDFVGLLVSPEM-----EQFALNMTSG---S 462
Cdd:pfam00685 131 DFLNGKVNCGSYFDHVKGWWKL--RPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLTEEEldkivKHLSFENMKGnpcL 208

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 157266319  463 GSSSKPFVVSARNATQAANAWRTALTFQQIKQVEEFCYQPMAVLG 507
Cdd:pfam00685 209 NYSKLPKEVSPFFRKGLVGDWKNYFTPEQAEKFDEIYQEKMKGTG 253
Sulfotransfer_3 pfam13469
Sulfotransferase family;
324-445 9.92e-08

Sulfotransferase family;


Pssm-ID: 463887  Cd Length: 173  Bit Score: 51.91  E-value: 9.92e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157266319  324 DLKVIHLVRDPRAVASSRIRSRHGLIRESLQVVRSRDprahrmpfleaaghklgakkegMGGPADYHALGAMEVICNSMA 403
Cdd:pfam13469  81 DAKFIHLHRDPVDTVISSYCSLFGFTLSSYSTAFLRD----------------------IGLALARWSRAYERLMAARAR 138

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 157266319  404 KtlqtalqPPDwlqgHYLVVRYEDLVGDPVKTLRRVYDFVGL 445
Cdd:pfam13469 139 V-------PPG----RFLDVRYEDLVADPEGTLRRILEFLGL 169
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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