|
Name |
Accession |
Description |
Interval |
E-value |
| dnaA |
PRK00149 |
chromosomal replication initiator protein DnaA; |
1-512 |
0e+00 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 234667 [Multi-domain] Cd Length: 401 Bit Score: 679.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 1 MSVELWQQCVDLLRDELPSQQFNTWIRPLQ-VEAEGDELRVYAPNRFVLDWVNEKYLGRllellgergegqlpalsllig 79
Cdd:PRK00149 1 NLQSLWEKVLERLKDELSEQEYETWIKPLKaLSLEDNTLTLYVPNRFVKDWIEKNYLDL--------------------- 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 80 skrsrtpraaivpsqthvappppvapppapvqpvsaapvvvpreelppvttapsvssdpyepeepsidplaaampagaap 159
Cdd:PRK00149 --------------------------------------------------------------------------------
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 160 avrternvqvegaLKHTSYLNRTFTFENFVEGKSNQLARAAAWQVADNLKHGYNPLFLYGGVGLGKTHLMHAVGNHLLKK 239
Cdd:PRK00149 60 -------------IEEALQLNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTHLLHAIGNYILEK 126
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 240 NPNAKVVYLHSERFVADMVKALQLNAINEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQVILTSDRYP 319
Cdd:PRK00149 127 NPNAKVVYVTSEKFTNDFVNALRNNTMEEFKEKYRSVDVLLIDDIQFLAGKERTQEEFFHTFNALHEAGKQIVLTSDRPP 206
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 320 KEIEGLEERLKSRFGWGLTVAVEPPELETRVAILMKKAEQAKIELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMGR 399
Cdd:PRK00149 207 KELPGLEERLRSRFEWGLTVDIEPPDLETRIAILKKKAEEEGIDLPDEVLEFIAKNITSNVRELEGALNRLIAYASLTGK 286
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 400 PITIELIRESLKDLLALQDKLVSIDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGVAFGGR 479
Cdd:PRK00149 287 PITLELAKEALKDLLAAQKKKITIENIQKVVAEYYNIKVSDLKSKSRTRNIARPRQIAMYLAKELTDLSLPEIGRAFGGR 366
|
490 500 510
....*....|....*....|....*....|...
gi 15595199 480 DHTTVLHACRKIAQLRESDADIREDYKNLLRTL 512
Cdd:PRK00149 367 DHTTVLHAVRKIEKLLEEDPELKEDVEELKRKL 399
|
|
| DnaA |
TIGR00362 |
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ... |
6-512 |
0e+00 |
|
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273037 [Multi-domain] Cd Length: 437 Bit Score: 668.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 6 WQQCVDLLRDELPSQQFNTWIRPLQVEA-EGDELRVYAPNRFVLDWVNEKYlgrllellgergegqLPALSLLIGSKRSR 84
Cdd:TIGR00362 1 WNRILERLEKELSEQEYNTWFKPLKLLSiEGNTLIISVPNEFVKEWIEKNY---------------LDLIEELLQELFGA 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 85 TPRAAIVpsqthvappppvapppapvqpvsaapVVVPREELPPVTTAPsvssdpyEPEEPSIDPlaaampagaapavrte 164
Cdd:TIGR00362 66 EIEIEFT--------------------------VGEDEEELEPNSKKP-------EPAPPEAPA---------------- 96
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 165 rnvqvegALKHTSYLNRTFTFENFVEGKSNQLARAAAWQVADNLKHGYNPLFLYGGVGLGKTHLMHAVGNHLLKKNPNAK 244
Cdd:TIGR00362 97 -------PPSSASGLNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTHLLHAIGNEILENNPNAK 169
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 245 VVYLHSERFVADMVKALQLNAINEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQVILTSDRYPKEIEG 324
Cdd:TIGR00362 170 VLYVSSEKFTNDFVNALRNNKMEEFKEKYRSVDLLLIDDIQFLAGKERTQEEFFHTFNALHENNKQIVLTSDRPPKELPG 249
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 325 LEERLKSRFGWGLTVAVEPPELETRVAILMKKAEQAKIELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMGRPITIE 404
Cdd:TIGR00362 250 LEDRLRSRFEWGLVVDIEPPDLETRLAILQKKAEEEGLELPDEVLEFIAKNITSNVRELEGALNRLLAYASLTGKPITLE 329
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 405 LIRESLKDLLALQDKLVSIDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGVAFGGRDHTTV 484
Cdd:TIGR00362 330 LAKEALKDLLRAQKKEITIENIQKVVAKYYNIKVSDLKSKKRTRNIVRPRQIAMYLAKELTDLSLPEIGKAFGGRDHTTV 409
|
490 500
....*....|....*....|....*...
gi 15595199 485 LHACRKIAQLRESDADIREDYKNLLRTL 512
Cdd:TIGR00362 410 LHAVRKIEKLIETDAELKEDIEELKRKL 437
|
|
| DnaA |
COG0593 |
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair]; |
179-481 |
0e+00 |
|
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
Pssm-ID: 440358 [Multi-domain] Cd Length: 303 Bit Score: 541.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 179 LNRTFTFENFVEGKSNQLARAAAWQVADNLKHGYNPLFLYGGVGLGKTHLMHAVGNHLLKKNPNAKVVYLHSERFVADMV 258
Cdd:COG0593 1 LNPRYTFDNFVVGPSNRLAHAAALAVAEWPGKAYNPLFLYGGVGLGKTHLLHAIGNEALENNPGARVVYLTAEEFTNDFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 259 KALQLNAINEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQVILTSDRYPKEIEGLEERLKSRFGWGLT 338
Cdd:COG0593 81 NAIRNNTIEEFKEKYRSVDVLLIDDIQFLAGKEATQEEFFHTFNALREAGKQIVLTSDRPPKELPGLEERLRSRLEWGLV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 339 VAVEPPELETRVAILMKKAEQAKIELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMGRPITIELIRESLKDLLALQD 418
Cdd:COG0593 161 VDIQPPDLETRIAILRKKAADRGLELPDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLKDLLRAQK 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15595199 419 KLVSIDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGVAFGGRDH 481
Cdd:COG0593 241 KEITIEDIQKAVAEYFGVSVADLLSKSRTREIARPRQIAMYLARELTDLSLPEIGRAFGGRDH 303
|
|
| Bac_DnaA |
pfam00308 |
Bacterial dnaA protein; |
179-396 |
3.73e-133 |
|
Bacterial dnaA protein;
Pssm-ID: 278724 [Multi-domain] Cd Length: 219 Bit Score: 384.76 E-value: 3.73e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 179 LNRTFTFENFVEGKSNQLARAAAWQVADNLKHGYNPLFLYGGVGLGKTHLMHAVGNHLLKKNPNAKVVYLHSERFVADMV 258
Cdd:pfam00308 1 LNPRYTFENFVIGPSNRFAHAAALTVAKAPGKAYNPLFIYGGVGLGKTHLLHAIGNYALQNAPNLRVVYLTAEEFLNDFV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 259 KALQLNAINEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQVILTSDRYPKEIEGLEERLKSRFGWGLT 338
Cdd:pfam00308 81 DAIRDNKTNQFKEKYRNVDVLLIDDIQFLAGKEGTQEEFFHTFNALHESGKQIVFSSDRPPKELEELEDRLRSRFQWGLV 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 15595199 339 VAVEPPELETRVAILMKKAEQAKIELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHF 396
Cdd:pfam00308 161 TDIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVRELEGALNRLLAYSSL 218
|
|
| Bac_DnaA_C |
cd06571 |
C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA ... |
423-512 |
2.60e-41 |
|
C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple copies of DnaA, which is an ATPase, bind to 9-mers at the origin and form an initial complex in which the DNA strands are being separated in an ATP-dependent step.
Pssm-ID: 119330 [Multi-domain] Cd Length: 90 Bit Score: 143.04 E-value: 2.60e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 423 IDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGVAFGGRDHTTVLHACRKIAQLRESDADIR 502
Cdd:cd06571 1 IELIIEAVAEYFGISVEDLRSKSRKKEIALARQIAMYLARELTGLSLPEIGRAFGGRDHSTVLHAVRKIEELLEEDPELK 80
|
90
....*....|
gi 15595199 503 EDYKNLLRTL 512
Cdd:cd06571 81 EDVEELEKKL 90
|
|
| Bac_DnaA_C |
smart00760 |
Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding. |
422-490 |
6.65e-36 |
|
Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.
Pssm-ID: 197863 [Multi-domain] Cd Length: 69 Bit Score: 127.62 E-value: 6.65e-36
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15595199 422 SIDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGVAFGGRDHTTVLHACRK 490
Cdd:smart00760 1 TIEEIIEAVAEYFGVKPEDLKSKSRKREIVLARQIAMYLARELTDLSLPEIGKIFGGRDHSTVLHACRK 69
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| dnaA |
PRK00149 |
chromosomal replication initiator protein DnaA; |
1-512 |
0e+00 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 234667 [Multi-domain] Cd Length: 401 Bit Score: 679.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 1 MSVELWQQCVDLLRDELPSQQFNTWIRPLQ-VEAEGDELRVYAPNRFVLDWVNEKYLGRllellgergegqlpalsllig 79
Cdd:PRK00149 1 NLQSLWEKVLERLKDELSEQEYETWIKPLKaLSLEDNTLTLYVPNRFVKDWIEKNYLDL--------------------- 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 80 skrsrtpraaivpsqthvappppvapppapvqpvsaapvvvpreelppvttapsvssdpyepeepsidplaaampagaap 159
Cdd:PRK00149 --------------------------------------------------------------------------------
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 160 avrternvqvegaLKHTSYLNRTFTFENFVEGKSNQLARAAAWQVADNLKHGYNPLFLYGGVGLGKTHLMHAVGNHLLKK 239
Cdd:PRK00149 60 -------------IEEALQLNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTHLLHAIGNYILEK 126
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 240 NPNAKVVYLHSERFVADMVKALQLNAINEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQVILTSDRYP 319
Cdd:PRK00149 127 NPNAKVVYVTSEKFTNDFVNALRNNTMEEFKEKYRSVDVLLIDDIQFLAGKERTQEEFFHTFNALHEAGKQIVLTSDRPP 206
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 320 KEIEGLEERLKSRFGWGLTVAVEPPELETRVAILMKKAEQAKIELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMGR 399
Cdd:PRK00149 207 KELPGLEERLRSRFEWGLTVDIEPPDLETRIAILKKKAEEEGIDLPDEVLEFIAKNITSNVRELEGALNRLIAYASLTGK 286
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 400 PITIELIRESLKDLLALQDKLVSIDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGVAFGGR 479
Cdd:PRK00149 287 PITLELAKEALKDLLAAQKKKITIENIQKVVAEYYNIKVSDLKSKSRTRNIARPRQIAMYLAKELTDLSLPEIGRAFGGR 366
|
490 500 510
....*....|....*....|....*....|...
gi 15595199 480 DHTTVLHACRKIAQLRESDADIREDYKNLLRTL 512
Cdd:PRK00149 367 DHTTVLHAVRKIEKLLEEDPELKEDVEELKRKL 399
|
|
| DnaA |
TIGR00362 |
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ... |
6-512 |
0e+00 |
|
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273037 [Multi-domain] Cd Length: 437 Bit Score: 668.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 6 WQQCVDLLRDELPSQQFNTWIRPLQVEA-EGDELRVYAPNRFVLDWVNEKYlgrllellgergegqLPALSLLIGSKRSR 84
Cdd:TIGR00362 1 WNRILERLEKELSEQEYNTWFKPLKLLSiEGNTLIISVPNEFVKEWIEKNY---------------LDLIEELLQELFGA 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 85 TPRAAIVpsqthvappppvapppapvqpvsaapVVVPREELPPVTTAPsvssdpyEPEEPSIDPlaaampagaapavrte 164
Cdd:TIGR00362 66 EIEIEFT--------------------------VGEDEEELEPNSKKP-------EPAPPEAPA---------------- 96
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 165 rnvqvegALKHTSYLNRTFTFENFVEGKSNQLARAAAWQVADNLKHGYNPLFLYGGVGLGKTHLMHAVGNHLLKKNPNAK 244
Cdd:TIGR00362 97 -------PPSSASGLNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTHLLHAIGNEILENNPNAK 169
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 245 VVYLHSERFVADMVKALQLNAINEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQVILTSDRYPKEIEG 324
Cdd:TIGR00362 170 VLYVSSEKFTNDFVNALRNNKMEEFKEKYRSVDLLLIDDIQFLAGKERTQEEFFHTFNALHENNKQIVLTSDRPPKELPG 249
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 325 LEERLKSRFGWGLTVAVEPPELETRVAILMKKAEQAKIELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMGRPITIE 404
Cdd:TIGR00362 250 LEDRLRSRFEWGLVVDIEPPDLETRLAILQKKAEEEGLELPDEVLEFIAKNITSNVRELEGALNRLLAYASLTGKPITLE 329
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 405 LIRESLKDLLALQDKLVSIDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGVAFGGRDHTTV 484
Cdd:TIGR00362 330 LAKEALKDLLRAQKKEITIENIQKVVAKYYNIKVSDLKSKKRTRNIVRPRQIAMYLAKELTDLSLPEIGKAFGGRDHTTV 409
|
490 500
....*....|....*....|....*...
gi 15595199 485 LHACRKIAQLRESDADIREDYKNLLRTL 512
Cdd:TIGR00362 410 LHAVRKIEKLIETDAELKEDIEELKRKL 437
|
|
| DnaA |
COG0593 |
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair]; |
179-481 |
0e+00 |
|
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
Pssm-ID: 440358 [Multi-domain] Cd Length: 303 Bit Score: 541.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 179 LNRTFTFENFVEGKSNQLARAAAWQVADNLKHGYNPLFLYGGVGLGKTHLMHAVGNHLLKKNPNAKVVYLHSERFVADMV 258
Cdd:COG0593 1 LNPRYTFDNFVVGPSNRLAHAAALAVAEWPGKAYNPLFLYGGVGLGKTHLLHAIGNEALENNPGARVVYLTAEEFTNDFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 259 KALQLNAINEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQVILTSDRYPKEIEGLEERLKSRFGWGLT 338
Cdd:COG0593 81 NAIRNNTIEEFKEKYRSVDVLLIDDIQFLAGKEATQEEFFHTFNALREAGKQIVLTSDRPPKELPGLEERLRSRLEWGLV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 339 VAVEPPELETRVAILMKKAEQAKIELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMGRPITIELIRESLKDLLALQD 418
Cdd:COG0593 161 VDIQPPDLETRIAILRKKAADRGLELPDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLKDLLRAQK 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15595199 419 KLVSIDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGVAFGGRDH 481
Cdd:COG0593 241 KEITIEDIQKAVAEYFGVSVADLLSKSRTREIARPRQIAMYLARELTDLSLPEIGRAFGGRDH 303
|
|
| Bac_DnaA |
pfam00308 |
Bacterial dnaA protein; |
179-396 |
3.73e-133 |
|
Bacterial dnaA protein;
Pssm-ID: 278724 [Multi-domain] Cd Length: 219 Bit Score: 384.76 E-value: 3.73e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 179 LNRTFTFENFVEGKSNQLARAAAWQVADNLKHGYNPLFLYGGVGLGKTHLMHAVGNHLLKKNPNAKVVYLHSERFVADMV 258
Cdd:pfam00308 1 LNPRYTFENFVIGPSNRFAHAAALTVAKAPGKAYNPLFIYGGVGLGKTHLLHAIGNYALQNAPNLRVVYLTAEEFLNDFV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 259 KALQLNAINEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQVILTSDRYPKEIEGLEERLKSRFGWGLT 338
Cdd:pfam00308 81 DAIRDNKTNQFKEKYRNVDVLLIDDIQFLAGKEGTQEEFFHTFNALHESGKQIVFSSDRPPKELEELEDRLRSRFQWGLV 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 15595199 339 VAVEPPELETRVAILMKKAEQAKIELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHF 396
Cdd:pfam00308 161 TDIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVRELEGALNRLLAYSSL 218
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
176-494 |
1.19e-107 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 333.72 E-value: 1.19e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 176 TSYLNRTFTFENFVEGKSNQLARAAAWQVADNLKHGYNPLFLYGGVGLGKTHLMHAVGNHLLKKNPNAKVVYLHSERFVA 255
Cdd:PRK14086 278 TARLNPKYTFDTFVIGASNRFAHAAAVAVAEAPAKAYNPLFIYGESGLGKTHLLHAIGHYARRLYPGTRVRYVSSEEFTN 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 256 DMVKALQLNAINEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQVILTSDRYPKEIEGLEERLKSRFGW 335
Cdd:PRK14086 358 EFINSIRDGKGDSFRRRYREMDILLVDDIQFLEDKESTQEEFFHTFNTLHNANKQIVLSSDRPPKQLVTLEDRLRNRFEW 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 336 GLTVAVEPPELETRVAILMKKAEQAKIELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMGRPITIELIRESLKDLLA 415
Cdd:PRK14086 438 GLITDVQPPELETRIAILRKKAVQEQLNAPPEVLEFIASRISRNIRELEGALIRVTAFASLNRQPVDLGLTEIVLRDLIP 517
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 416 LQDKL-VSIDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGVAFgGRDHTTVLHACRKIAQL 494
Cdd:PRK14086 518 EDSAPeITAAAIMAATADYFGLTVEDLCGTSRSRVLVTARQIAMYLCRELTDLSLPKIGQQF-GRDHTTVMHADRKIRAL 596
|
|
| PRK12422 |
PRK12422 |
chromosomal replication initiator protein DnaA; |
179-513 |
4.58e-70 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 183521 [Multi-domain] Cd Length: 445 Bit Score: 230.88 E-value: 4.58e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 179 LNRTFTFENFVEGKSNQLARAAAWQVA--DNLKHG--YNPLFLYGGVGLGKTHLMHAVGNHLlkKNPNAKVVYLHSERFV 254
Cdd:PRK12422 104 LDPLMTFANFLVTPENDLPHRILQEFTkvSEQGKGfpFNPIYLFGPEGSGKTHLMQAAVHAL--RESGGKILYVRSELFT 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 255 ADMVKALQLNAINEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQVILTSDRYPKEIEGLEERLKSRFG 334
Cdd:PRK12422 182 EHLVSAIRSGEMQRFRQFYRNVDALFIEDIEVFSGKGATQEEFFHTFNSLHTEGKLIVISSTCAPQDLKAMEERLISRFE 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 335 WGLTVAVEPPELETRVAILMKKAEQAKIELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMG---RPITIELIRESLK 411
Cdd:PRK12422 262 WGIAIPLHPLTKEGLRSFLERKAEALSIRIEETALDFLIEALSSNVKSLLHALTLLAKRVAYKKlshQLLYVDDIKALLH 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 412 DLLALQDKL-VSIDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGVAFgGRDHTTVLHACRK 490
Cdd:PRK12422 342 DVLEAAESVrLTPSKIIRAVAQYYGVSPESILGRSQSREYVLPRQVAMYLCRQKLSLSYVKIGDVF-SRDHSTVISSIRA 420
|
330 340
....*....|....*....|....
gi 15595199 491 IAQ-LRESDADIREDYKNLLRTLT 513
Cdd:PRK12422 421 ISQkLEEDDRDISMAIQEITKRLS 444
|
|
| Bac_DnaA_C |
cd06571 |
C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA ... |
423-512 |
2.60e-41 |
|
C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple copies of DnaA, which is an ATPase, bind to 9-mers at the origin and form an initial complex in which the DNA strands are being separated in an ATP-dependent step.
Pssm-ID: 119330 [Multi-domain] Cd Length: 90 Bit Score: 143.04 E-value: 2.60e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 423 IDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGVAFGGRDHTTVLHACRKIAQLRESDADIR 502
Cdd:cd06571 1 IELIIEAVAEYFGISVEDLRSKSRKKEIALARQIAMYLARELTGLSLPEIGRAFGGRDHSTVLHAVRKIEELLEEDPELK 80
|
90
....*....|
gi 15595199 503 EDYKNLLRTL 512
Cdd:cd06571 81 EDVEELEKKL 90
|
|
| Bac_DnaA_C |
pfam08299 |
Bacterial dnaA protein helix-turn-helix; |
423-491 |
1.45e-38 |
|
Bacterial dnaA protein helix-turn-helix;
Pssm-ID: 462419 [Multi-domain] Cd Length: 69 Bit Score: 134.84 E-value: 1.45e-38
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15595199 423 IDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGVAFGGRDHTTVLHACRKI 491
Cdd:pfam08299 1 IEKIIEAVAEYFGISPEDLKSKSRKREIALARQIAMYLARELTDLSLPEIGRAFGGRDHSTVIHACKKI 69
|
|
| Bac_DnaA_C |
smart00760 |
Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding. |
422-490 |
6.65e-36 |
|
Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.
Pssm-ID: 197863 [Multi-domain] Cd Length: 69 Bit Score: 127.62 E-value: 6.65e-36
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15595199 422 SIDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGVAFGGRDHTTVLHACRK 490
Cdd:smart00760 1 TIEEIIEAVAEYFGVKPEDLKSKSRKREIVLARQIAMYLARELTDLSLPEIGKIFGGRDHSTVLHACRK 69
|
|
| DnaA_homol_Hda |
TIGR03420 |
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ... |
184-411 |
8.58e-26 |
|
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274571 [Multi-domain] Cd Length: 226 Bit Score: 105.35 E-value: 8.58e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 184 TFENFVEGkSNQLARAAAWQVADNlkHGYNPLFLYGGVGLGKTHLMHAVGNHLLKKNPNAkvVYLhSERFVADMVKALqL 263
Cdd:TIGR03420 13 TFDNFYAG-GNAELLAALRQLAAG--KGDRFLYLWGESGSGKSHLLQAACAAAEERGKSA--IYL-PLAELAQADPEV-L 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 264 NAINEFkrfyrsvDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQVILTSDRYPKEIEGLEERLKSRFGWGLTVAVEP 343
Cdd:TIGR03420 86 EGLEQA-------DLVCLDDVEAIAGQPEWQEALFHLYNRVREAGGRLLIAGRAAPAQLPLRLPDLRTRLAWGLVFQLPP 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15595199 344 PELETRVAILMKKAEQAKIELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMGRPITIELIRESLK 411
Cdd:TIGR03420 159 LSDEEKIAALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDRASLAAKRKITIPFVKEVLA 226
|
|
| DnaA_N |
pfam11638 |
DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a ... |
4-55 |
5.76e-18 |
|
DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a protein involved in the initiation of bacterial chromosomal replication. The structure of this domain is known. It is also found in three copies in some proteins. The exact function of this domain is uncertain but it has been suggested to play a role in oligomerization.
Pssm-ID: 463316 [Multi-domain] Cd Length: 65 Bit Score: 78.09 E-value: 5.76e-18
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 15595199 4 ELWQQCVDLLRDELPSQQFNTWIRPLQVEA--EGDELRVYAPNRFVLDWVNEKY 55
Cdd:pfam11638 2 ELWERVLERLRKEVGEQTFNTWIKPLTLVDldDGGSLTLSVPNRFVRDWVEEHY 55
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
212-337 |
2.53e-17 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 79.11 E-value: 2.53e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 212 YNPLFLYGGVGLGKTHLMHAVGNHLlkKNPNAKVVYLHSERFVADMVKALQLNAINEFKRF----YRSVDALLIDDIQFF 287
Cdd:cd00009 19 PKNLLLYGPPGTGKTTLARAIANEL--FRPGAPFLYLNASDLLEGLVVAELFGHFLVRLLFelaeKAKPGVLFIDEIDSL 96
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 15595199 288 ARKERSQ-EEFFHTFNALLE--GGQQVILTSDR--YPKEIEGLEERLKSRFGWGL 337
Cdd:cd00009 97 SRGAQNAlLRVLETLNDLRIdrENVRVIGATNRplLGDLDRALYDRLDIRIVIPL 151
|
|
| PRK08084 |
PRK08084 |
DnaA inactivator Hda; |
178-411 |
2.00e-16 |
|
DnaA inactivator Hda;
Pssm-ID: 181224 [Multi-domain] Cd Length: 235 Bit Score: 78.57 E-value: 2.00e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 178 YLNRTFTFENFVEGKSNQLAraAAWQVADNLKHGyNPLFLYGGVGLGKTHLMHAVGNHLLKKNPNAKVVYLHSER-FVAD 256
Cdd:PRK08084 14 YLPDDETFASFYPGDNDSLL--AALQNALRQEHS-GYIYLWSREGAGRSHLLHAACAELSQRGRAVGYVPLDKRAwFVPE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 257 MVKALQlnainefkrfyrSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQ-QVILTSDRYPKEIEGLEERLKSRFGW 335
Cdd:PRK08084 91 VLEGME------------QLSLVCIDNIECIAGDELWEMAIFDLYNRILESGRtRLLITGDRPPRQLNLGLPDLASRLDW 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15595199 336 GLTVAVEPPELETRVAILMKKAEQAKIELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMGRPITIELIRESLK 411
Cdd:PRK08084 159 GQIYKLQPLSDEEKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILK 234
|
|
| PRK08903 |
PRK08903 |
DnaA regulatory inactivator Hda; Validated |
184-414 |
9.25e-16 |
|
DnaA regulatory inactivator Hda; Validated
Pssm-ID: 236347 [Multi-domain] Cd Length: 227 Bit Score: 76.55 E-value: 9.25e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 184 TFENFVEGksnqlARAAAWQVADNLKHGYNP---LFLYGGVGLGKTHLMHAVGNHLLKKNPNAkvVYLhserfvaDMVKA 260
Cdd:PRK08903 16 TFDNFVAG-----ENAELVARLRELAAGPVAdrfFYLWGEAGSGRSHLLQALVADASYGGRNA--RYL-------DAASP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 261 LQLNAinefkrFYRSVDALLIDDIQffARKERSQEEFFHTFNALLEGGQQVILTSDRYPKEIEGLEERLKSRFGWGLTVA 340
Cdd:PRK08903 82 LLAFD------FDPEAELYAVDDVE--RLDDAQQIALFNLFNRVRAHGQGALLVAGPAAPLALPLREDLRTRLGWGLVYE 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15595199 341 VEPPELETRVAILMKKAEQAKIELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMGRPITIELIRESLKDLL 414
Cdd:PRK08903 154 LKPLSDADKIAALKAAAAERGLQLADEVPDYLLTHFRRDMPSLMALLDALDRYSLEQKRPVTLPLLREMLAQPE 227
|
|
| DnaC |
COG1484 |
DNA replication protein DnaC [Replication, recombination and repair]; |
162-315 |
1.46e-12 |
|
DNA replication protein DnaC [Replication, recombination and repair];
Pssm-ID: 441093 [Multi-domain] Cd Length: 242 Bit Score: 67.50 E-value: 1.46e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 162 RTERNVQvegALKHTSYLNRTFTFENFVEGKSNQLARAAAWQVADN--LKHGYNpLFLYGGVGLGKTHLMHAVGNHLLKK 239
Cdd:COG1484 51 REQRRIE---RRLKAARFPAAKTLEDFDFDAQPGLDRRQILELATLdfIERGEN-LILLGPPGTGKTHLAIALGHEACRA 126
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15595199 240 NPnaKVVYLHSERFVADMVKALQLNAINEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGqQVILTS 315
Cdd:COG1484 127 GY--RVRFTTAPDLVNELKEARADGRLERLLKRLAKVDLLILDELGYLPLDAEGAELLFELISDRYERR-STIITS 199
|
|
| PRK06030 |
PRK06030 |
hypothetical protein; Provisional |
426-499 |
5.39e-10 |
|
hypothetical protein; Provisional
Pssm-ID: 180356 Cd Length: 124 Bit Score: 57.09 E-value: 5.39e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15595199 426 IQRTVAEYYKIKISDLLS-KRRSRSVARPRQVAMALSKelTNHSLPEIGVAFG-GRDHTTVLHACRKIAQLRESDA 499
Cdd:PRK06030 28 VIDLLALAFGVSGAEIASpLRGRREVSRIRQIAMYVAH--VSLGWPMNEVALAfGRDRTTVGHACHTVEDLRDDAA 101
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
213-332 |
6.87e-09 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 54.69 E-value: 6.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 213 NPLFLYGGVGLGKTHLMHAVGNHLLKknPNAKVVYLHSERFVADMVKALQLNAINEFKRF---------------YRSVD 277
Cdd:smart00382 3 EVILIVGPPGSGKTTLARALARELGP--PGGGVIYIDGEDILEEVLDQLLLIIVGGKKASgsgelrlrlalalarKLKPD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 278 ALLIDDIQFFARKERSQEEFFHTFNALL-----EGGQQVILTSDRYPKEIEGLEERLKSR 332
Cdd:smart00382 81 VLILDEITSLLDAEQEALLLLLEELRLLlllksEKNLTVILTTNDEKDLGPALLRRRFDR 140
|
|
| PRK08939 |
PRK08939 |
primosomal protein DnaI; Reviewed |
194-284 |
1.55e-07 |
|
primosomal protein DnaI; Reviewed
Pssm-ID: 236353 [Multi-domain] Cd Length: 306 Bit Score: 52.95 E-value: 1.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 194 NQLARAAAWQVADNLKHGYNP------LFLYGGVGLGKTHLMHAVGNHLLKKNPNAKVVYLHSerFVADMVKALQLNAIN 267
Cdd:PRK08939 132 DDRDRLDALMAALDFLEAYPPgekvkgLYLYGDFGVGKSYLLAAIANELAKKGVSSTLLHFPE--FIRELKNSISDGSVK 209
|
90
....*....|....*..
gi 15595199 268 EFKRFYRSVDALLIDDI 284
Cdd:PRK08939 210 EKIDAVKEAPVLMLDDI 226
|
|
| PRK12377 |
PRK12377 |
putative replication protein; Provisional |
179-284 |
3.90e-07 |
|
putative replication protein; Provisional
Pssm-ID: 183482 [Multi-domain] Cd Length: 248 Bit Score: 51.37 E-value: 3.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 179 LNRTFTFENF-VEGKSNQLARAAAWQVADNLKHGYNPLFLYGGVGLGKTHLMHAVGNHLLKKNPNAKVVYlhserfVADM 257
Cdd:PRK12377 67 LHRKCSFANYqVQNDGQRYALSQAKSIADELMTGCTNFVFSGKPGTGKNHLAAAIGNRLLAKGRSVIVVT------VPDV 140
|
90 100 110
....*....|....*....|....*....|..
gi 15595199 258 VKALQLNAIN-----EFKRFYRSVDALLIDDI 284
Cdd:PRK12377 141 MSRLHESYDNgqsgeKFLQELCKVDLLVLDEI 172
|
|
| PRK06835 |
PRK06835 |
DNA replication protein DnaC; Validated |
215-332 |
5.39e-07 |
|
DNA replication protein DnaC; Validated
Pssm-ID: 235871 [Multi-domain] Cd Length: 329 Bit Score: 51.44 E-value: 5.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 215 LFLYGGVGLGKTHLMHAVGNHLLKKnpnAK-VVYLHSERFVaDMVKALQLNAINEFKRFY---RSVDALLIDDIQFFARK 290
Cdd:PRK06835 186 LLFYGNTGTGKTFLSNCIAKELLDR---GKsVIYRTADELI-EILREIRFNNDKELEEVYdllINCDLLIIDDLGTEKIT 261
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 15595199 291 ERSQEEFFHTFNALLEGGQQVILTSDRYPKEIEGL-EERLKSR 332
Cdd:PRK06835 262 EFSKSELFNLINKRLLRQKKMIISTNLSLEELLKTySERISSR 304
|
|
| PRK08116 |
PRK08116 |
hypothetical protein; Validated |
162-332 |
1.51e-06 |
|
hypothetical protein; Validated
Pssm-ID: 236153 [Multi-domain] Cd Length: 268 Bit Score: 49.63 E-value: 1.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 162 RTERNVQVEgALKHTSYLNRTF---TFENF-VEGKSNQLARAAAWQV-------ADNLKhgynpLFLYGGVGLGKTHLMH 230
Cdd:PRK08116 59 NREKQRRIE-RLKSNSLLDEKFrnsTFENFlFDKGSEKAYKIARKYVkkfeemkKENVG-----LLLWGSVGTGKTYLAA 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 231 AVGNHLLKKnpNAKVVYLHSERFVADMVKALQLNAI---NEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEG 307
Cdd:PRK08116 133 CIANELIEK--GVPVIFVNFPQLLNRIKSTYKSSGKedeNEIIRSLVNADLLILDDLGAERDTEWAREKVYNIIDSRYRK 210
|
170 180
....*....|....*....|....*.
gi 15595199 308 GQQVILTSDRYPKEI-EGLEERLKSR 332
Cdd:PRK08116 211 GLPTIVTTNLSLEELkNQYGKRIYDR 236
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
217-412 |
1.77e-04 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 43.75 E-value: 1.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 217 LYGGVGLGKTHLMHAVGN----HLLKKNPnAKVV--YL-HSERFVADMV-KALQL-NAInefkrfyrsvdaLLIDDIQFF 287
Cdd:COG0464 196 LYGPPGTGKTLLARALAGelglPLIEVDL-SDLVskYVgETEKNLREVFdKARGLaPCV------------LFIDEADAL 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 288 ARKERSQEEFFHT--FNALL---EGGQQ---VILTSDRypkeIEGLEERLKSRFgwGLTVAVEPPELETRVAILMKKAEQ 359
Cdd:COG0464 263 AGKRGEVGDGVGRrvVNTLLtemEELRSdvvVIAATNR----PDLLDPALLRRF--DEIIFFPLPDAEERLEIFRIHLRK 336
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 15595199 360 AKIELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMGR-PITIELIRESLKD 412
Cdd:COG0464 337 RPLDEDVDLEELAEATEGLSGADIRNVVRRAALQALRLGRePVTTEDLLEALER 390
|
|
| PRK06921 |
PRK06921 |
hypothetical protein; Provisional |
181-332 |
3.06e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 180750 [Multi-domain] Cd Length: 266 Bit Score: 42.46 E-value: 3.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 181 RTFTFENFV-EGKSNqlARAAAWQVADNLKHGY--------NPLFLYGGVGLGKTHLMHAVGNHLLKKNPNAKVVYLHSE 251
Cdd:PRK06921 79 RKLTFKNFKtEGKPQ--AIKDAYECAVEYVKDFekiqesrkNSIALLGQPGSGKTHLLTAAANELMRKKGVPVLYFPFVE 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 252 RFvaDMVKALqLNAINEFKRFYRSVDALLIDDI-QFFARKERSQ----EEFFHTFNALLEGGQQVILTSDRYPKEIEGLE 326
Cdd:PRK06921 157 GF--GDLKDD-FDLLEAKLNRMKKVEVLFIDDLfKPVNGKPRATewqiEQMYSVLNYRYLNHKPILISSELTIDELLDID 233
|
....*.
gi 15595199 327 ERLKSR 332
Cdd:PRK06921 234 EALGSR 239
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
203-360 |
6.50e-04 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 42.14 E-value: 6.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 203 QVADNLK---HGYNP--LFLYGGVGLGKTHLMHAVGNHL----LKKNPNAKVVY-----LHSE-RFVADMVKALQLNA-I 266
Cdd:COG1474 37 ELASALRpalRGERPsnVLIYGPTGTGKTAVAKYVLEELeeeaEERGVDVRVVYvncrqASTRyRVLSRILEELGSGEdI 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 267 NE--------FKRFYRSVDA----LLI--DDIQFFARKERSQE-EFFHTFNALLEGGQ-QVILTSdRYPKEIEGLEERLK 330
Cdd:COG1474 117 PStglstdelFDRLYEALDErdgvLVVvlDEIDYLVDDEGDDLlYQLLRANEELEGARvGVIGIS-NDLEFLENLDPRVK 195
|
170 180 190
....*....|....*....|....*....|...
gi 15595199 331 SRFGwGLTVAVEP---PELetrVAILMKKAEQA 360
Cdd:COG1474 196 SSLG-EEEIVFPPydaDEL---RDILEDRAELA 224
|
|
| PRK07952 |
PRK07952 |
DNA replication protein DnaC; Validated |
161-284 |
1.39e-03 |
|
DNA replication protein DnaC; Validated
Pssm-ID: 181180 [Multi-domain] Cd Length: 244 Bit Score: 40.52 E-value: 1.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15595199 161 VRTERNVQVEGALKHTSYLNRT--------FTFENF-VEGKSNQLARAAAWQVADNLKHGYNPLFLYGGVGLGKTHLMHA 231
Cdd:PRK07952 39 IRSAALERENRAMKMQRTFNRSgirplhqnCSFENYrVECEGQMNALSKARQYVEEFDGNIASFIFSGKPGTGKNHLAAA 118
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15595199 232 VGNHLLKKNPNAKVVYlhserfVADMVKAL----------QLNAINEFKrfyrSVDALLIDDI 284
Cdd:PRK07952 119 ICNELLLRGKSVLIIT------VADIMSAMkdtfsnsetsEEQLLNDLS----NVDLLVIDEI 171
|
|
| KISc_KIF3 |
cd01371 |
Kinesin motor domain, kinesins II or KIF3_like proteins; Kinesin motor domain, kinesins II or ... |
181-229 |
2.75e-03 |
|
Kinesin motor domain, kinesins II or KIF3_like proteins; Kinesin motor domain, kinesins II or KIF3_like proteins. Subgroup of kinesins, which form heterotrimers composed of 2 kinesins and one non-motor accessory subunit. Kinesins II play important roles in ciliary transport, and have been implicated in neuronal transport, melanosome transport, the secretory pathway, and mitosis. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Kinesins are microtubule-dependent molecular motors that play important roles in intracellular transport and in cell division. In this group the motor domain is found at the N-terminus (N-type). N-type kinesins are (+) end-directed motors, i.e. they transport cargo towards the (+) end of the microtubule. Kinesin motor domains hydrolyze ATP at a rate of about 80 per second, and move along the microtubule at a speed of about 6400 Angstroms per second. To achieve that, kinesin head groups work in pairs. Upon replacing ADP with ATP, a kinesin motor domain increases its affinity for microtubule binding and locks in place. Also, the neck linker binds to the motor domain, which repositions the other head domain through the coiled-coil domain close to a second tubulin dimer, about 80 Angstroms along the microtubule. Meanwhile, ATP hydrolysis takes place, and when the second head domain binds to the microtubule, the first domain again replaces ADP with ATP, triggering a conformational change that pulls the first domain forward.
Pssm-ID: 276822 [Multi-domain] Cd Length: 334 Bit Score: 40.14 E-value: 2.75e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 15595199 181 RTFTFENFVEGKSNQ--LARAAAWQVADNLKHGYN-PLFLYGGVGLGKTHLM 229
Cdd:cd01371 48 KTFTFDAVFDPNSKQldVYDETARPLVDSVLEGYNgTIFAYGQTGTGKTYTM 99
|
|
| PRK06672 |
PRK06672 |
hypothetical protein; Validated |
6-55 |
5.54e-03 |
|
hypothetical protein; Validated
Pssm-ID: 180654 [Multi-domain] Cd Length: 341 Bit Score: 38.97 E-value: 5.54e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 15595199 6 WQQCVDLLRDELPSQQFNTWIRPLQVEAEGDELRVYAPNRFVLDWVNEKY 55
Cdd:PRK06672 5 WTEVKEKIRPQISKPSYETWFTNTTVYLEDDILTIYCPNEFARDWLESHY 54
|
|
| |
