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Conserved domains on  [gi|21735575|ref|NP_065698|]
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junctophilin-1 [Homo sapiens]

Protein Classification

MORN repeat-containing protein( domain architecture ID 11468649)

membrane-occupation-and-recognition-nexus (MORN) repeat-containing protein may be involved in protein-protein interactions

PubMed:  33296386|35568981

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
3-333 6.66e-24

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 101.96  E-value: 6.66e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575   3 GGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETkgkwmy 82
Cdd:COG4642  93 GGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLT------ 166

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575  83 rgeWSHGfkgrygvrqslctpARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSvpygmatvirsplrts 162
Cdd:COG4642 167 ---YADG--------------DRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTY---------------- 213

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575 163 laslrseqSNGSVlhdaaaaadspagtrggfvlnfhadaelagkkkgglfrrgsllgsmklrkseskssisskrssvrsd 242
Cdd:COG4642 214 --------ADGDR------------------------------------------------------------------- 218

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575 243 aamsrisssdanstisfgdvdcdfcpvedhvdatttetYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFP 322
Cdd:COG4642 219 --------------------------------------YEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMTYA 260

                       330
                ....*....|.
gi 21735575 323 DGSKEEGKYKN 333
Cdd:COG4642 261 DGSVYEGEWKN 271
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 405-571 7.40e-04

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 7.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575   405 ARAVARELSpdfyQPGPDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPeasPKHSHSPASSPKPLK 484
Cdd:PHA03247 2879 ARPPVRRLA----RPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPP---PRPQPPLAPTTDPAG 2951

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575   485 KQNPSSGARLNQDKRSVADEqvTAIVNKPLMSKAPTKEAgavvPQSKYSGRHHIPNP------SNGELHSQYHGYYVKLN 558
Cdd:PHA03247 2952 AGEPSGAVPQPWLGALVPGR--VAVPRFRVPQPAPSREA----PASSTPPLTGHSLSrvsswaSSLALHEETDPPPVSLK 3025

                         170
                  ....*....|...
gi 21735575   559 APQHPPVDVEDGD 571
Cdd:PHA03247 3026 QTLWPPDDTEDSD 3038
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
3-333 6.66e-24

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 101.96  E-value: 6.66e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575   3 GGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETkgkwmy 82
Cdd:COG4642  93 GGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLT------ 166

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575  83 rgeWSHGfkgrygvrqslctpARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSvpygmatvirsplrts 162
Cdd:COG4642 167 ---YADG--------------DRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTY---------------- 213

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575 163 laslrseqSNGSVlhdaaaaadspagtrggfvlnfhadaelagkkkgglfrrgsllgsmklrkseskssisskrssvrsd 242
Cdd:COG4642 214 --------ADGDR------------------------------------------------------------------- 218

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575 243 aamsrisssdanstisfgdvdcdfcpvedhvdatttetYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFP 322
Cdd:COG4642 219 --------------------------------------YEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMTYA 260

                       330
                ....*....|.
gi 21735575 323 DGSKEEGKYKN 333
Cdd:COG4642 261 DGSVYEGEWKN 271
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 4-143 1.29e-21

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 99.91  E-value: 1.29e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575    4 GRFDFDDGGTYCGGWEEGKAHGHGICTGPKG---QGEYSGSWSHGFevvGGYTWPSGNTYQGYWAQGKRHGLGVETKGKW 80
Cdd:PLN03185  24 GKYLWSDGCMYEGEWRRGMRHGNGKISWPSGatyEGEFSGGYMHGS---GTYTGTDGTTYKGRWRLNLKHGLGYQRYPNG 100

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21735575   81 -MYRGEWSHGFK---GRYgvrqSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
Cdd:PLN03185 101 dVFEGSWIQGLQegpGKY----TWANGNVYLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGV 163
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 304-326 9.22e-05

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 39.70  E-value: 9.22e-05
                          10        20
                  ....*....|....*....|...
gi 21735575   304 YEGEWANNKRHGYGCTVFPDGSK 326
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
303-323 4.69e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 37.71  E-value: 4.69e-04
                           10        20
                   ....*....|....*....|.
gi 21735575    303 KYEGEWANNKRHGYGCTVFPD 323
Cdd:smart00698   2 RYEGEWRNGKRHGRGVYTYAN 22
PHA03247 PHA03247
large tegument protein UL36; Provisional
 405-571 7.40e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 7.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575   405 ARAVARELSpdfyQPGPDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPeasPKHSHSPASSPKPLK 484
Cdd:PHA03247 2879 ARPPVRRLA----RPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPP---PRPQPPLAPTTDPAG 2951

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575   485 KQNPSSGARLNQDKRSVADEqvTAIVNKPLMSKAPTKEAgavvPQSKYSGRHHIPNP------SNGELHSQYHGYYVKLN 558
Cdd:PHA03247 2952 AGEPSGAVPQPWLGALVPGR--VAVPRFRVPQPAPSREA----PASSTPPLTGHSLSrvsswaSSLALHEETDPPPVSLK 3025

                         170
                  ....*....|...
gi 21735575   559 APQHPPVDVEDGD 571
Cdd:PHA03247 3026 QTLWPPDDTEDSD 3038
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
3-333 6.66e-24

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 101.96  E-value: 6.66e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575   3 GGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETkgkwmy 82
Cdd:COG4642  93 GGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLT------ 166

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575  83 rgeWSHGfkgrygvrqslctpARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSvpygmatvirsplrts 162
Cdd:COG4642 167 ---YADG--------------DRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTY---------------- 213

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575 163 laslrseqSNGSVlhdaaaaadspagtrggfvlnfhadaelagkkkgglfrrgsllgsmklrkseskssisskrssvrsd 242
Cdd:COG4642 214 --------ADGDR------------------------------------------------------------------- 218

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575 243 aamsrisssdanstisfgdvdcdfcpvedhvdatttetYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFP 322
Cdd:COG4642 219 --------------------------------------YEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMTYA 260

                       330
                ....*....|.
gi 21735575 323 DGSKEEGKYKN 333
Cdd:COG4642 261 DGSVYEGEWKN 271
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
2-143 1.60e-23

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 100.80  E-value: 1.60e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575   2 TGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGqGEYSGSWSHG-FEVVGGYTWPSGNTYQGYWAQGKRHGlgvetKGKW 80
Cdd:COG4642 138 GGGIYTFPNGDVYEGEFKNGKPHGQGTLTYADG-DRYEGEFKNGkRHGQGTLTYANGDVYEGEFKNGQRHG-----QGTY 211

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 21735575  81 MyrgeWSHGFkgrygvrqslctpaRYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
Cdd:COG4642 212 T----YADGD--------------RYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGT 256
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 4-143 1.29e-21

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 99.91  E-value: 1.29e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575    4 GRFDFDDGGTYCGGWEEGKAHGHGICTGPKG---QGEYSGSWSHGFevvGGYTWPSGNTYQGYWAQGKRHGLGVETKGKW 80
Cdd:PLN03185  24 GKYLWSDGCMYEGEWRRGMRHGNGKISWPSGatyEGEFSGGYMHGS---GTYTGTDGTTYKGRWRLNLKHGLGYQRYPNG 100

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21735575   81 -MYRGEWSHGFK---GRYgvrqSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
Cdd:PLN03185 101 dVFEGSWIQGLQegpGKY----TWANGNVYLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGV 163
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
9-336 7.46e-20

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 90.02  E-value: 7.46e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575   9 DDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWM-YRGEWS 87
Cdd:COG4642  41 PGGGGYGGGADGGGGGGGGTGVAGGGGGEGGVTAAGGGGGGGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGgGGGVLE 120

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575  88 HGFKGRYGVRQS--------LCTPA---RYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQsvpygmatvir 156
Cdd:COG4642 121 GDDGGGYGGGTAdggrggggIYTFPngdVYEGEFKNGKPHGQGTLTYADGDRYEGEFKNGKRHGQGTLT----------- 189

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575 157 splrtslaslrseQSNGSVlhdaaaaadspagtrggfvlnfhadaelagkkkgglfrrgsllgsmklrkseskssisskr 236
Cdd:COG4642 190 -------------YANGDV------------------------------------------------------------- 195

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575 237 ssvrsdaamsrisssdanstisfgdvdcdfcpvedhvdatttetYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGY 316
Cdd:COG4642 196 --------------------------------------------YEGEFKNGQRHGQGTYTYADGDRYEGEFKNGKRHGQ 231

                       330       340
                ....*....|....*....|
gi 21735575 317 GCTVFPDGSKEEGKYKNNIL 336
Cdd:COG4642 232 GTLTYADGDRYEGEFKNGKR 251
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 38-150 8.75e-11

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 65.24  E-value: 8.75e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575   38 YSGSWSHGF-EVVGGYTWPSGNTYQGYWAQGKRHGlgvetKGKWMyrgeWSHGfkgrygvrqslctpARYEGTWSNGLQD 116
Cdd:PLN03185  11 YSGSLLGNVpEGPGKYLWSDGCMYEGEWRRGMRHG-----NGKIS----WPSG--------------ATYEGEFSGGYMH 67

                         90       100       110
                 ....*....|....*....|....*....|....
gi 21735575  117 GYGVETYGDGGTYQGQWAGGMRHGYGvRQSVPYG 150
Cdd:PLN03185  68 GSGTYTGTDGTTYKGRWRLNLKHGLG-YQRYPNG 100
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 106-325 1.83e-05

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 47.91  E-value: 1.83e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575  106 YEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGvrqsvpygmatVIRSPlrtSLASLRSEQSNGsVLHDAAAAADS 185
Cdd:PLN03185  11 YSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNG-----------KISWP---SGATYEGEFSGG-YMHGSGTYTGT 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575  186 PAGT-RGGFVLNFhadaelagkkKGGLFRRGSLLGSMklrkseskssisskrssvRSDAAMSRISSSDANSTISFGDVdc 264
Cdd:PLN03185  76 DGTTyKGRWRLNL----------KHGLGYQRYPNGDV------------------FEGSWIQGLQEGPGKYTWANGNV-- 125

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 21735575  265 dfcpvedhvdatttetYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGS 325
Cdd:PLN03185 126 ----------------YLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYTWSDGG 170
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
283-337 3.82e-05

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 44.67  E-value: 3.82e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 21735575 283 GEWKNDKRNGFGVSERSNG-MKYEGEWANNKRHGYGCTVFPDGS-KEEGKYKNNILV 337
Cdd:COG2849  83 GTYKNGKLEGEWKEYYENGkLKSEGNYKNGKLHGEWKEYYENGKlKEEGNYKNGKKD 139
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 304-326 9.22e-05

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 39.70  E-value: 9.22e-05
                          10        20
                  ....*....|....*....|...
gi 21735575   304 YEGEWANNKRHGYGCTVFPDGSK 326
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 280-332 1.44e-04

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 45.21  E-value: 1.44e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 21735575  280 TYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYK 332
Cdd:PLN03185  56 TYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSWI 108
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 106-128 3.08e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 38.16  E-value: 3.08e-04
                          10        20
                  ....*....|....*....|...
gi 21735575   106 YEGTWSNGLQDGYGVETYGDGGT 128
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
303-323 4.69e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 37.71  E-value: 4.69e-04
                           10        20
                   ....*....|....*....|.
gi 21735575    303 KYEGEWANNKRHGYGCTVFPD 323
Cdd:smart00698   2 RYEGEWRNGKRHGRGVYTYAN 22
PHA03247 PHA03247
large tegument protein UL36; Provisional
 405-571 7.40e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 7.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575   405 ARAVARELSpdfyQPGPDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPeasPKHSHSPASSPKPLK 484
Cdd:PHA03247 2879 ARPPVRRLA----RPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPP---PRPQPPLAPTTDPAG 2951

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575   485 KQNPSSGARLNQDKRSVADEqvTAIVNKPLMSKAPTKEAgavvPQSKYSGRHHIPNP------SNGELHSQYHGYYVKLN 558
Cdd:PHA03247 2952 AGEPSGAVPQPWLGALVPGR--VAVPRFRVPQPAPSREA----PASSTPPLTGHSLSrvsswaSSLALHEETDPPPVSLK 3025

                         170
                  ....*....|...
gi 21735575   559 APQHPPVDVEDGD 571
Cdd:PHA03247 3026 QTLWPPDDTEDSD 3038
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 280-335 8.10e-04

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 42.51  E-value: 8.10e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 21735575  280 TYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
Cdd:PLN03185  33 MYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNL 88
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
283-337 9.85e-04

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 40.44  E-value: 9.85e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 21735575 283 GEWKNDKRNGFGVSERSNG-MKYEGEWANNKRHGYGCTVFPDGS-KEEGKYKNNILV 337
Cdd:COG2849 107 GNYKNGKLHGEWKEYYENGkLKEEGNYKNGKKDGVWKYYDENGKlVKEEEYKNGKKV 163
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 279-331 1.04e-03

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 42.13  E-value: 1.04e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 21735575  279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKY 331
Cdd:PLN03185   9 DFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEF 61
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 55-142 1.38e-03

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 41.74  E-value: 1.38e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21735575   55 PSGNTYQGYWaqgkrHGLGVETKGKWMyrgeWSHGfkgrygvrqslCTparYEGTWSNGLQDGYGVETYGDGGTYQGQWA 134
Cdd:PLN03185   6 SNGDFYSGSL-----LGNVPEGPGKYL----WSDG-----------CM---YEGEWRRGMRHGNGKISWPSGATYEGEFS 62


                 ....*...
gi 21735575  135 GGMRHGYG 142
Cdd:PLN03185  63 GGYMHGSG 70
PRK10819 PRK10819
transport protein TonB; Provisional
 435-493 3.91e-03

transport protein TonB; Provisional


Pssm-ID: 236768 [Multi-domain]  Cd Length: 246  Bit Score: 39.67  E-value: 3.91e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 21735575  435 KENPEEKVPE------KPPTPKESPHFYRKG---TTPPRSPEASPKHSHSPASSPKPLKKQNPSSGAR 493
Cdd:PRK10819 106 KPKPVKKVEEqpkrevKPVEPRPASPFENTAparPTSSTATAAASKPVTSVSSGPRALSRNQPQYPAR 173
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
104-125 1.00e-02

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 33.85  E-value: 1.00e-02
                           10        20
                   ....*....|....*....|..
gi 21735575    104 ARYEGTWSNGLQDGYGVETYGD 125
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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