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Conserved domains on  [gi|86355510|ref|NP_075616|]
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DNA-directed RNA polymerases I, II, and III subunit RPABC4 isoform b [Mus musculus]

Protein Classification

Rpo12/RPC10 RNA polymerase subunit family protein( domain architecture ID 10652796)

Rpo12/RPC10 RNA polymerase subunit family protein similar to DNA-directed RNA polymerases I, II, and III subunit RPABC4, a common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively

Gene Ontology:  GO:0006351|GO:0003899|GO:0003677
PubMed:  24219496|18280161

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RPOLCX smart00659
RNA polymerase subunit CX; present in RNA polymerase I, II and III
 15-58 9.29e-19

RNA polymerase subunit CX; present in RNA polymerase I, II and III


:

Pssm-ID: 128906  Cd Length: 44  Bit Score: 70.85  E-value: 9.29e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 86355510    15 MIYICGECHTENEIKSRDPIRCRECGYRIMYKKRTKRLVVFDAR 58
Cdd:smart00659  1 MIYICGECGRENEIKSKDVVRCRECGYRILYKKRTKRLVEVKAR 44
 
Name Accession Description Interval E-value
RPOLCX smart00659
RNA polymerase subunit CX; present in RNA polymerase I, II and III
 15-58 9.29e-19

RNA polymerase subunit CX; present in RNA polymerase I, II and III


Pssm-ID: 128906  Cd Length: 44  Bit Score: 70.85  E-value: 9.29e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 86355510    15 MIYICGECHTENEIKSRDPIRCRECGYRIMYKKRTKRLVVFDAR 58
Cdd:smart00659  1 MIYICGECGRENEIKSKDVVRCRECGYRILYKKRTKRLVEVKAR 44
DNA_RNApol_7kD pfam03604
DNA directed RNA polymerase, 7 kDa subunit;
17-48 3.78e-13

DNA directed RNA polymerase, 7 kDa subunit;


Pssm-ID: 427393  Cd Length: 32  Bit Score: 56.15  E-value: 3.78e-13
                         10        20        30
                 ....*....|....*....|....*....|..
gi 86355510   17 YICGECHTENEIKSRDPIRCRECGYRIMYKKR 48
Cdd:pfam03604  1 YICGECGAEVSLKRGDPIRCKECGHRILYKKR 32
RPC10 COG1996
DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger [Transcription]; ...
 15-58 8.06e-03

DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger [Transcription]; DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441599  Cd Length: 48  Bit Score: 30.44  E-value: 8.06e-03
                       10        20        30        40
               ....*....|....*....|....*....|....*....|....*
gi 86355510 15 MIYICGECHTENEIKSRDP-IRCRECGYRIMYKKRTKRLVVFDAR 58
Cdd:COG1996  4 VEYKCPRCGAEVELDEGTPaIRCPYCGSRIFIKERPPVVKRVKAI 48
 
Name Accession Description Interval E-value
RPOLCX smart00659
RNA polymerase subunit CX; present in RNA polymerase I, II and III
 15-58 9.29e-19

RNA polymerase subunit CX; present in RNA polymerase I, II and III


Pssm-ID: 128906  Cd Length: 44  Bit Score: 70.85  E-value: 9.29e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 86355510    15 MIYICGECHTENEIKSRDPIRCRECGYRIMYKKRTKRLVVFDAR 58
Cdd:smart00659  1 MIYICGECGRENEIKSKDVVRCRECGYRILYKKRTKRLVEVKAR 44
DNA_RNApol_7kD pfam03604
DNA directed RNA polymerase, 7 kDa subunit;
17-48 3.78e-13

DNA directed RNA polymerase, 7 kDa subunit;


Pssm-ID: 427393  Cd Length: 32  Bit Score: 56.15  E-value: 3.78e-13
                         10        20        30
                 ....*....|....*....|....*....|..
gi 86355510   17 YICGECHTENEIKSRDPIRCRECGYRIMYKKR 48
Cdd:pfam03604  1 YICGECGAEVSLKRGDPIRCKECGHRILYKKR 32
RPC10 COG1996
DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger [Transcription]; ...
 15-58 8.06e-03

DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger [Transcription]; DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441599  Cd Length: 48  Bit Score: 30.44  E-value: 8.06e-03
                       10        20        30        40
               ....*....|....*....|....*....|....*....|....*
gi 86355510 15 MIYICGECHTENEIKSRDP-IRCRECGYRIMYKKRTKRLVVFDAR 58
Cdd:COG1996  4 VEYKCPRCGAEVELDEGTPaIRCPYCGSRIFIKERPPVVKRVKAI 48
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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