|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
68-322 |
1.20e-34 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 135.83 E-value: 1.20e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 68 QNLSFSSTERWWDQTDLTKLIISSNKLQSLSDDLRLLPALTVLDIHDNQLTSLPSAIRELDNLQKLNVSHNKLKILPEEI 147
Cdd:COG4886 99 TELDLSGNEELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEEL 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 148 TSLKNLRTLHLQHNELTCIPEGFEHLSCLEDLDLSSNrlatvpadfallssllrlnlssnQLKNLPAEISRMKRLKHLDC 227
Cdd:COG4886 179 GNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGN-----------------------QLTDLPEPLANLTNLETLDL 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 228 DANLLETVpPDVGSMESLELLYLRRNKLRVLPEFPSCRQLKELHLAENQIEKLGAEHLQHLQAILVLDLRGNKLRSVPEE 307
Cdd:COG4886 236 SNNQLTDL-PELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELL 314
|
250
....*....|....*
gi 31541911 308 MALLQSLERLDLSNN 322
Cdd:COG4886 315 ILLLLLTTLLLLLLL 329
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
120-577 |
6.22e-23 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 103.77 E-value: 6.22e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 120 LPSAIRELDNLQKLNVSHNKLKI-LPEEI-TSLKNLRTLHLQHNELT-CIPEGFehLSCLEDLDLSSNRLAtvpadfall 196
Cdd:PLN00113 85 ISSAIFRLPYIQTINLSNNQLSGpIPDDIfTTSSSLRYLNLSNNNFTgSIPRGS--IPNLETLDLSNNMLS--------- 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 197 ssllrlnlssnqlKNLPAEISRMKRLKHLDCDANLLE-TVPPDVGSMESLELLYLRRNKL--RVLPEFPSCRQLKELHLA 273
Cdd:PLN00113 154 -------------GEIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLvgQIPRELGQMKSLKWIYLG 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 274 ENQIEKLGAEHLQHLQAILVLDLRGNKLR-SVPEEMALLQSLERLDLSNNDIS-SLPCSLGNL-HLKFLALEGNPLRTIR 350
Cdd:PLN00113 221 YNNLSGEIPYEIGGLTSLNHLDLVYNNLTgPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLqKLISLDLSDNSLSGEI 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 351 REIIAK-GTQEVLKYLRSKIkddrtnqNDSVPETAMTLP-------------SEARVNIHAIATLKLLDYSDKQAT-LIP 415
Cdd:PLN00113 301 PELVIQlQNLEILHLFSNNF-------TGKIPVALTSLPrlqvlqlwsnkfsGEIPKNLGKHNNLTVLDLSTNNLTgEIP 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 416 DDLFDATKttLITSINFSKNQLCEIPQRIVELKEMVlDINLSFNKLSF-ISHELCLLQKLTFLDLR-NNFLSSLPEEMSS 493
Cdd:PLN00113 374 EGLCSSGN--LFKLILFSNSLEGEIPKSLGACRSLR-RVRLQDNSFSGeLPSEFTKLPLVYFLDISnNNLQGRINSRKWD 450
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 494 LTKLQTINLSFNRFKVFPEVLYRISTLEAVLISNNQVGSVDPQKMKLMENLNTLDLQNNDLL-QIPPELGNCVQLRTLLL 572
Cdd:PLN00113 451 MPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDL 530
|
....*
gi 31541911 573 DGNPF 577
Cdd:PLN00113 531 SHNQL 535
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
317-578 |
7.63e-21 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 95.39 E-value: 7.63e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 317 LDLSNNDISSLPCSLGNLHLKFLALEGNPLRTIRREIIAKGTQEVLKYLRSKIKDDRTNQNDSVPETAMTLPSEARVNIH 396
Cdd:COG4886 14 LLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 397 AIATLKLLDYSDkqatliPDDLFDATKttlITSINFSKNQLCEIPQRIVELKEMVlDINLSFNKLSFISHELCLLQKLTF 476
Cdd:COG4886 94 DLTNLTELDLSG------NEELSNLTN---LESLDLSGNQLTDLPEELANLTNLK-ELDLSNNQLTDLPEPLGNLTNLKS 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 477 LDLRNNFLSSLPEEMSSLTKLQTINLSFNRFKVFPEVLYRISTLEAVLISNNQVGSVdPQKMKLMENLNTLDLQNNDLLQ 556
Cdd:COG4886 164 LDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTD 242
|
250 260
....*....|....*....|..
gi 31541911 557 IpPELGNCVQLRTLLLDGNPFR 578
Cdd:COG4886 243 L-PELGNLTNLEELDLSNNQLT 263
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
84-290 |
2.11e-15 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 79.74 E-value: 2.11e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 84 LTKLIISSNKLQSLSDDLRllPALTVLDIHDNQLTS----LPSAIRELD---------------NLQKLNVSHNKLKILP 144
Cdd:PRK15370 201 ITTLILDNNELKSLPENLQ--GNIKTLYANSNQLTSipatLPDTIQEMElsinritelperlpsALQSLDLFHNKISCLP 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 145 EEITslKNLRTLHLQHNELTCIPegfEHL-SCLEDLDLSSNRLATVPADFALLSSLLRLNLSSnqLKNLPAEISrmKRLK 223
Cdd:PRK15370 279 ENLP--EELRYLSVYDNSIRTLP---AHLpSGITHLNVQSNSLTALPETLPPGLKTLEAGENA--LTSLPASLP--PELQ 349
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 31541911 224 HLDCDAN----LLETVPPdvgsmeSLELLYLRRNKLRVLPE-FPSCrqLKELHLAENQIEKLgAEHLQHLQA 290
Cdd:PRK15370 350 VLDVSKNqitvLPETLPP------TITTLDVSRNALTNLPEnLPAA--LQIMQASRNNLVRL-PESLPHFRG 412
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
145-355 |
4.06e-15 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 74.82 E-value: 4.06e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 145 EEITSLKNLRTLHLQHNELTCIpEGFEHLSCLEDLDLSSNRlatvpadfallssllrlnlssnqlknlpaeISRMKRLKH 224
Cdd:cd21340 18 DNLSLCKNLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQ------------------------------IEKIENLEN 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 225 LdcdanlletvppdvgsmESLELLYLRRNKLRVLPEFPSCRQLKELHLaENQieKLGAEH--------LQHLQAIL-VLD 295
Cdd:cd21340 67 L-----------------VNLKKLYLGGNRISVVEGLENLTNLEELHI-ENQ--RLPPGEkltfdprsLAALSNSLrVLN 126
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 31541911 296 LRGNKLRSVpEEMALLQSLERLDLSNNDISSLP---CSLGNL-HLKFLALEGNPLRTIRR---EIIA 355
Cdd:cd21340 127 ISGNNIDSL-EPLAPLRNLEQLDASNNQISDLEellDLLSSWpSLRELDLTGNPVCKKPKyrdKIIL 192
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
129-186 |
6.84e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 49.45 E-value: 6.84e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 129 NLQKLNVSHNKLKILPEEI-TSLKNLRTLHLQHNELTCI-PEGFEHLSCLEDLDLSSNRL 186
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
248-505 |
4.56e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 45.16 E-value: 4.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 248 LYLRRNKLRVLPEFPSCRQLKELHLAENQIEKLgaEHLQHLQAILVLDLRGNKLRSVpEEMALLQSLERLDLSNNDISSL 327
Cdd:cd21340 7 LYLNDKNITKIDNLSLCKNLKVLYLYDNKITKI--ENLEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 328 pCSLGNLH-LKFLALEgnplrtirreiiakgtqevlkylrskikddrtNQNDSvPETAMTLPSEArvnIHAIA-TLKLLd 405
Cdd:cd21340 84 -EGLENLTnLEELHIE--------------------------------NQRLP-PGEKLTFDPRS---LAALSnSLRVL- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 406 ysdkqatlipddlfdatkttlitsinfsknqlceipqrivelkemvldiNLSFNKLSFIShELCLLQKLTFLDLRNNFLS 485
Cdd:cd21340 126 -------------------------------------------------NISGNNIDSLE-PLAPLRNLEQLDASNNQIS 155
|
250 260
....*....|....*....|...
gi 31541911 486 SLPE---EMSSLTKLQTINLSFN 505
Cdd:cd21340 156 DLEElldLLSSWPSLRELDLTGN 178
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
454-507 |
1.74e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 37.12 E-value: 1.74e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 31541911 454 INLSFNKLSFISHELCL-LQKLTFLDLRNNFLSSL-PEEMSSLTKLQTINLSFNRF 507
Cdd:pfam13855 6 LDLSNNRLTSLDDGAFKgLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
68-322 |
1.20e-34 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 135.83 E-value: 1.20e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 68 QNLSFSSTERWWDQTDLTKLIISSNKLQSLSDDLRLLPALTVLDIHDNQLTSLPSAIRELDNLQKLNVSHNKLKILPEEI 147
Cdd:COG4886 99 TELDLSGNEELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEEL 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 148 TSLKNLRTLHLQHNELTCIPEGFEHLSCLEDLDLSSNrlatvpadfallssllrlnlssnQLKNLPAEISRMKRLKHLDC 227
Cdd:COG4886 179 GNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGN-----------------------QLTDLPEPLANLTNLETLDL 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 228 DANLLETVpPDVGSMESLELLYLRRNKLRVLPEFPSCRQLKELHLAENQIEKLGAEHLQHLQAILVLDLRGNKLRSVPEE 307
Cdd:COG4886 236 SNNQLTDL-PELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELL 314
|
250
....*....|....*
gi 31541911 308 MALLQSLERLDLSNN 322
Cdd:COG4886 315 ILLLLLTTLLLLLLL 329
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
67-431 |
4.12e-34 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 134.29 E-value: 4.12e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 67 NQNLSFSSTERWWDQTDLTKLIISSNklqslsDDLRLLPALTVLDIHDNQLTSLPSAIRELDNLQKLNVSHNKLKILPEE 146
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEP 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 147 ITSLKNLRTLHLQHNELTCIPEGFEHLSCLEDLDLSSNrlatvpadfallssllrlnlssnQLKNLPAEISRMKRLKHLD 226
Cdd:COG4886 155 LGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNN-----------------------QITDLPEPLGNLTNLEELD 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 227 CDANLLETVPPDVGSMESLELLYLRRNKLRVLPEFPSCRQLKELHLAENQIEKLGaeHLQHLQAILVLDLRGNKLRSVPE 306
Cdd:COG4886 212 LSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLP--PLANLTNLKTLDLSNNQLTDLKL 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 307 EMALLQSLERLDLSNNDISSLPCSLGNLHLKFLALEGNPLRTIRREIIAKGTQEVLKYLRSKIKDDRTNQNDSVPETAMT 386
Cdd:COG4886 290 KELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTL 369
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 31541911 387 LPSEARVNIHAIATLKLLDYSDKQATLIPDDLFDATKTTLITSIN 431
Cdd:COG4886 370 GLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
67-365 |
7.05e-32 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 128.13 E-value: 7.05e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 67 NQNLSFSSTERWWDQTDLTKLIISSNKLQSLSDDLRLLPALTVLDIHDNQLTSLPSAIRELDNLQKLNVSHNklkilpEE 146
Cdd:COG4886 35 LALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN------EE 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 147 ITSLKNLRTLHLQHNELTCIPEGFEHLSCLEDLDLSSNrlatvpadfallssllrlnlssnQLKNLPAEISRMKRLKHLD 226
Cdd:COG4886 109 LSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNN-----------------------QLTDLPEPLGNLTNLKSLD 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 227 CDANLLETVPPDVGSMESLELLYLRRNKLRVLP-EFPSCRQLKELHLAENQIEKLGAEhLQHLQAILVLDLRGNKLRSVP 305
Cdd:COG4886 166 LSNNQLTDLPEELGNLTNLKELDLSNNQITDLPePLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNNQLTDLP 244
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 306 eEMALLQSLERLDLSNNDISSLPCSLGNLHLKFLALEGNPLRTIRREIIAKGTQEVLKYL 365
Cdd:COG4886 245 -ELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLL 303
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
120-577 |
6.22e-23 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 103.77 E-value: 6.22e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 120 LPSAIRELDNLQKLNVSHNKLKI-LPEEI-TSLKNLRTLHLQHNELT-CIPEGFehLSCLEDLDLSSNRLAtvpadfall 196
Cdd:PLN00113 85 ISSAIFRLPYIQTINLSNNQLSGpIPDDIfTTSSSLRYLNLSNNNFTgSIPRGS--IPNLETLDLSNNMLS--------- 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 197 ssllrlnlssnqlKNLPAEISRMKRLKHLDCDANLLE-TVPPDVGSMESLELLYLRRNKL--RVLPEFPSCRQLKELHLA 273
Cdd:PLN00113 154 -------------GEIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLvgQIPRELGQMKSLKWIYLG 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 274 ENQIEKLGAEHLQHLQAILVLDLRGNKLR-SVPEEMALLQSLERLDLSNNDIS-SLPCSLGNL-HLKFLALEGNPLRTIR 350
Cdd:PLN00113 221 YNNLSGEIPYEIGGLTSLNHLDLVYNNLTgPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLqKLISLDLSDNSLSGEI 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 351 REIIAK-GTQEVLKYLRSKIkddrtnqNDSVPETAMTLP-------------SEARVNIHAIATLKLLDYSDKQAT-LIP 415
Cdd:PLN00113 301 PELVIQlQNLEILHLFSNNF-------TGKIPVALTSLPrlqvlqlwsnkfsGEIPKNLGKHNNLTVLDLSTNNLTgEIP 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 416 DDLFDATKttLITSINFSKNQLCEIPQRIVELKEMVlDINLSFNKLSF-ISHELCLLQKLTFLDLR-NNFLSSLPEEMSS 493
Cdd:PLN00113 374 EGLCSSGN--LFKLILFSNSLEGEIPKSLGACRSLR-RVRLQDNSFSGeLPSEFTKLPLVYFLDISnNNLQGRINSRKWD 450
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 494 LTKLQTINLSFNRFKVFPEVLYRISTLEAVLISNNQVGSVDPQKMKLMENLNTLDLQNNDLL-QIPPELGNCVQLRTLLL 572
Cdd:PLN00113 451 MPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDL 530
|
....*
gi 31541911 573 DGNPF 577
Cdd:PLN00113 531 SHNQL 535
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
317-578 |
7.63e-21 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 95.39 E-value: 7.63e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 317 LDLSNNDISSLPCSLGNLHLKFLALEGNPLRTIRREIIAKGTQEVLKYLRSKIKDDRTNQNDSVPETAMTLPSEARVNIH 396
Cdd:COG4886 14 LLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 397 AIATLKLLDYSDkqatliPDDLFDATKttlITSINFSKNQLCEIPQRIVELKEMVlDINLSFNKLSFISHELCLLQKLTF 476
Cdd:COG4886 94 DLTNLTELDLSG------NEELSNLTN---LESLDLSGNQLTDLPEELANLTNLK-ELDLSNNQLTDLPEPLGNLTNLKS 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 477 LDLRNNFLSSLPEEMSSLTKLQTINLSFNRFKVFPEVLYRISTLEAVLISNNQVGSVdPQKMKLMENLNTLDLQNNDLLQ 556
Cdd:COG4886 164 LDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTD 242
|
250 260
....*....|....*....|..
gi 31541911 557 IpPELGNCVQLRTLLLDGNPFR 578
Cdd:COG4886 243 L-PELGNLTNLEELDLSNNQLT 263
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
395-577 |
1.25e-20 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 94.62 E-value: 1.25e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 395 IHAIATLKLLDYSDKQATLIPDDLFDATKttlITSINFSKNQLCEIPQRIVELKEMVlDINLSFNKLSFISHELCLLQKL 474
Cdd:COG4886 109 LSNLTNLESLDLSGNQLTDLPEELANLTN---LKELDLSNNQLTDLPEPLGNLTNLK-SLDLSNNQLTDLPEELGNLTNL 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 475 TFLDLRNNFLSSLPEEMSSLTKLQTINLSFNRFKVFPEVLYRISTLEAVLISNNQVGSVDpqKMKLMENLNTLDLQNNDL 554
Cdd:COG4886 185 KELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP--ELGNLTNLEELDLSNNQL 262
|
170 180
....*....|....*....|...
gi 31541911 555 LQIPPeLGNCVQLRTLLLDGNPF 577
Cdd:COG4886 263 TDLPP-LANLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
176-573 |
5.81e-17 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 83.44 E-value: 5.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 176 LEDLDLSSNRLATVPADFALLSSLLRLNLSSNQLKNLPAEISRMKRLKHLDCDANLLETVPPDVGSMESLELLYLRRNKL 255
Cdd:COG4886 24 LILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 256 RVLPEFPSCRQLKELHLAENQIEKLGAEhLQHLQAILVLDLRGNKLRSVPEEMALLQSLERLDLSNNDISSLPCSLGNLh 335
Cdd:COG4886 104 SGNEELSNLTNLESLDLSGNQLTDLPEE-LANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNL- 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 336 lkflalegnplrtirreiiakgtqevlkylrskikddrtnqndsvpetamtlpsearvnihaiatlklldysdkqatlip 415
Cdd:COG4886 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 416 ddlfdatktTLITSINFSKNQLCEIPQRIVELKEMVlDINLSFNKLSFISHELCLLQKLTFLDLRNNFLSSLPeEMSSLT 495
Cdd:COG4886 182 ---------TNLKELDLSNNQITDLPEPLGNLTNLE-ELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLT 250
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 31541911 496 KLQTINLSFNRFKVFPEvLYRISTLEAVLISNNQVGSVDPQKMKLMENLNTLDLQNNDLLQIPPELGNCVQLRTLLLD 573
Cdd:COG4886 251 NLEELDLSNNQLTDLPP-LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLL 327
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
89-575 |
1.69e-16 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 83.36 E-value: 1.69e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 89 ISSNKLQ-SLSDDL-RLLPALTVLDIHDNQLT-SLPSAirELDNLQKLNVSHNKLK-ILPEEITSLKNLRTLHLQHNELT 164
Cdd:PLN00113 100 LSNNQLSgPIPDDIfTTSSSLRYLNLSNNNFTgSIPRG--SIPNLETLDLSNNMLSgEIPNDIGSFSSLKVLDLGGNVLV 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 165 C-IPEGFEHLSCLEDLDLSSNRL-ATVPADFALLSSLLRLNLSSNQLK-NLPAEISRMKRLKHLD-CDANLLETVPPDVG 240
Cdd:PLN00113 178 GkIPNSLTNLTSLEFLTLASNQLvGQIPRELGQMKSLKWIYLGYNNLSgEIPYEIGGLTSLNHLDlVYNNLTGPIPSSLG 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 241 SMESLELLYLRRNKL--RVLPEFPSCRQLKELHLAEN-----------QIEKLGAEHL-------------QHLQAILVL 294
Cdd:PLN00113 258 NLKNLQYLFLYQNKLsgPIPPSIFSLQKLISLDLSDNslsgeipelviQLQNLEILHLfsnnftgkipvalTSLPRLQVL 337
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 295 DLRGNKLR-SVPEEMALLQSLERLDLSNNDISS-LP---CSLGNLHLKFL---ALEGNplrtirreiIAKGTQEVLKYLR 366
Cdd:PLN00113 338 QLWSNKFSgEIPKNLGKHNNLTVLDLSTNNLTGeIPeglCSSGNLFKLILfsnSLEGE---------IPKSLGACRSLRR 408
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 367 SKIKDDrtNQNDSVPETAMTLPseaRVNIHAIATLKLLDYSDKQATLIPD-------------DLFDATKTTLITSINFS 433
Cdd:PLN00113 409 VRLQDN--SFSGELPSEFTKLP---LVYFLDISNNNLQGRINSRKWDMPSlqmlslarnkffgGLPDSFGSKRLENLDLS 483
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 434 KNQLCE-IPQRIVELKEMvLDINLSFNKLSfishelcllqkltfldlrnnflSSLPEEMSSLTKLQTINLSFNRFK-VFP 511
Cdd:PLN00113 484 RNQFSGaVPRKLGSLSEL-MQLKLSENKLS----------------------GEIPDELSSCKKLVSLDLSHNQLSgQIP 540
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 31541911 512 EVLYRISTLEAVLISNNQVGSVDPQKMKLMENLNTLDLQNNDLLQIPPELGNCVQLRTLLLDGN 575
Cdd:PLN00113 541 ASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGN 604
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
84-290 |
2.11e-15 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 79.74 E-value: 2.11e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 84 LTKLIISSNKLQSLSDDLRllPALTVLDIHDNQLTS----LPSAIRELD---------------NLQKLNVSHNKLKILP 144
Cdd:PRK15370 201 ITTLILDNNELKSLPENLQ--GNIKTLYANSNQLTSipatLPDTIQEMElsinritelperlpsALQSLDLFHNKISCLP 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 145 EEITslKNLRTLHLQHNELTCIPegfEHL-SCLEDLDLSSNRLATVPADFALLSSLLRLNLSSnqLKNLPAEISrmKRLK 223
Cdd:PRK15370 279 ENLP--EELRYLSVYDNSIRTLP---AHLpSGITHLNVQSNSLTALPETLPPGLKTLEAGENA--LTSLPASLP--PELQ 349
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 31541911 224 HLDCDAN----LLETVPPdvgsmeSLELLYLRRNKLRVLPE-FPSCrqLKELHLAENQIEKLgAEHLQHLQA 290
Cdd:PRK15370 350 VLDVSKNqitvLPETLPP------TITTLDVSRNALTNLPEnLPAA--LQIMQASRNNLVRL-PESLPHFRG 412
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
145-355 |
4.06e-15 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 74.82 E-value: 4.06e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 145 EEITSLKNLRTLHLQHNELTCIpEGFEHLSCLEDLDLSSNRlatvpadfallssllrlnlssnqlknlpaeISRMKRLKH 224
Cdd:cd21340 18 DNLSLCKNLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQ------------------------------IEKIENLEN 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 225 LdcdanlletvppdvgsmESLELLYLRRNKLRVLPEFPSCRQLKELHLaENQieKLGAEH--------LQHLQAIL-VLD 295
Cdd:cd21340 67 L-----------------VNLKKLYLGGNRISVVEGLENLTNLEELHI-ENQ--RLPPGEkltfdprsLAALSNSLrVLN 126
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 31541911 296 LRGNKLRSVpEEMALLQSLERLDLSNNDISSLP---CSLGNL-HLKFLALEGNPLRTIRR---EIIA 355
Cdd:cd21340 127 ISGNNIDSL-EPLAPLRNLEQLDASNNQISDLEellDLLSSWpSLRELDLTGNPVCKKPKyrdKIIL 192
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
83-343 |
3.24e-14 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 76.04 E-value: 3.24e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 83 DLTKLI---ISSNKLQSLSDDLRL-LPALTVLDIHDNQLT-SLPSAIRELDNLQKLNVSHNKLK-ILPEEITSLKNLRTL 156
Cdd:PLN00113 282 SLQKLIsldLSDNSLSGEIPELVIqLQNLEILHLFSNNFTgKIPVALTSLPRLQVLQLWSNKFSgEIPKNLGKHNNLTVL 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 157 HLQHNELTC-IPEGFEHLSCLEDLDLSSNRL-ATVPADFALLSSLLRLNLSSNQLK-NLPAEISRMKRLKHLD-CDANLL 232
Cdd:PLN00113 362 DLSTNNLTGeIPEGLCSSGNLFKLILFSNSLeGEIPKSLGACRSLRRVRLQDNSFSgELPSEFTKLPLVYFLDiSNNNLQ 441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 233 ETVPPDVGSMESLELLYLRRNK-LRVLPEFPSCRQLKELHLAENQIEKLGAEHLQHLQAILVLDLRGNKLRSV-PEEMAL 310
Cdd:PLN00113 442 GRINSRKWDMPSLQMLSLARNKfFGGLPDSFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEiPDELSS 521
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 31541911 311 LQSLERLDLSNNDIS-SLPCS------LGNLHLKFLALEG 343
Cdd:PLN00113 522 CKKLVSLDLSHNQLSgQIPASfsempvLSQLDLSQNQLSG 561
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
32-192 |
1.45e-12 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 70.65 E-value: 1.45e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 32 LKAARSSGQLNLAGRNL-GEVPQCVWRIN-VDIPEEANQNLSFSSTERWWDQTDLTKLIISSNKLQSLSDDLRLLPALTV 109
Cdd:PLN00113 400 LGACRSLRRVRLQDNSFsGELPSEFTKLPlVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLEN 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 110 LDIHDNQLT-SLPSAIRELDNLQKLNVSHNKLK-ILPEEITSLKNLRTLHLQHNELTC-IPEGFEHLSCLEDLDLSSNRL 186
Cdd:PLN00113 480 LDLSRNQFSgAVPRKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQLSGqIPASFSEMPVLSQLDLSQNQL 559
|
....*..
gi 31541911 187 A-TVPAD 192
Cdd:PLN00113 560 SgEIPKN 566
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
209-514 |
1.12e-11 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 67.80 E-value: 1.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 209 LKNLPAEIsRMKRLKhldcdanlLETVPPDVGsmESLELLYLRRNKLRVLPEFPSCrQLKELHLAENQIEKLGAEHLQHL 288
Cdd:PRK15370 176 LKNNKTEL-RLKILG--------LTTIPACIP--EQITTLILDNNELKSLPENLQG-NIKTLYANSNQLTSIPATLPDTI 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 289 QailVLDLRGNKLRSVPEEmaLLQSLERLDLSNNDISSLPCSLGNlHLKFLALEGNPLRTIRreiiakgtqevlKYLRSK 368
Cdd:PRK15370 244 Q---EMELSINRITELPER--LPSALQSLDLFHNKISCLPENLPE-ELRYLSVYDNSIRTLP------------AHLPSG 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 369 IKDDRTnQNDSVPETAMTLPsearvnihaiATLKLLDYSDKQATLIPDDLFDATKTtlitsINFSKNQLCEIPQrivelk 448
Cdd:PRK15370 306 ITHLNV-QSNSLTALPETLP----------PGLKTLEAGENALTSLPASLPPELQV-----LDVSKNQITVLPE------ 363
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 31541911 449 emvldinlsfnklsfishelCLLQKLTFLDLRNNFLSSLPEEMSSltKLQTINLSFNRFKVFPEVL 514
Cdd:PRK15370 364 --------------------TLPPTITTLDVSRNALTNLPENLPA--ALQIMQASRNNLVRLPESL 407
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
84-325 |
4.69e-11 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 65.95 E-value: 4.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 84 LTKLIISSNKLQSLSddlRLLPALTVLDIHDNQLTSLPSAIrelDNLQKLNVSHNKLKILPEEITSLKNLRTLHLQHNEL 163
Cdd:PRK15387 224 ITTLVIPDNNLTSLP---ALPPELRTLEVSGNQLTSLPVLP---PGLLELSIFSNPLTHLPALPSGLCKLWIFGNQLTSL 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 164 TCIPEGfehlscLEDLDLSSNRLATVPAdfaLLSSLLRLNLSSNQLKNLPAEISRMKRLKHLDCDANLLETVPPDVGSM- 242
Cdd:PRK15387 298 PVLPPG------LQELSVSDNQLASLPA---LPSELCKLWAYNNQLTSLPTLPSGLQELSVSDNQLASLPTLPSELYKLw 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 243 -------------ESLELLYLRRNKLRVLPEFPScrQLKELHLAENQIEKLGAEHlqhlQAILVLDLRGNKLRSVPEEMA 309
Cdd:PRK15387 369 aynnrltslpalpSGLKELIVSGNRLTSLPVLPS--ELKELMVSGNRLTSLPMLP----SGLLSLSVYRNQLTRLPESLI 442
|
250
....*....|....*.
gi 31541911 310 LLQSLERLDLSNNDIS 325
Cdd:PRK15387 443 HLSSETTVNLEGNPLS 458
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
49-255 |
4.67e-10 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 62.56 E-value: 4.67e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 49 GEVPQCVW-RINVDIPEEANQNLSFSSTERWWDQTDLTKLIISSNKLQS-------------------------LSDDLR 102
Cdd:PLN00113 346 GEIPKNLGkHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGeipkslgacrslrrvrlqdnsfsgeLPSEFT 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 103 LLPALTVLDIHDNQLT-SLPSAIRELDNLQKLNVSHNK-LKILPEEITSlKNLRTLHLQHNELT-CIPEGFEHLSCLEDL 179
Cdd:PLN00113 426 KLPLVYFLDISNNNLQgRINSRKWDMPSLQMLSLARNKfFGGLPDSFGS-KRLENLDLSRNQFSgAVPRKLGSLSELMQL 504
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 31541911 180 DLSSNRLA-TVPADFALLSSLLRLNLSSNQLK-NLPAEISRMKRLKHLDCDANLLE-TVPPDVGSMESLELLYLRRNKL 255
Cdd:PLN00113 505 KLSENKLSgEIPDELSSCKKLVSLDLSHNQLSgQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHNHL 583
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
303-577 |
2.23e-09 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 60.48 E-value: 2.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 303 SVPEEMALLQslerldLSNNDISSLPcslGNLH--LKFLALEGNPLRTIRREIiaKGTQEVLKYLRSKIKDdrtnqndsV 380
Cdd:PRK15370 196 CIPEQITTLI------LDNNELKSLP---ENLQgnIKTLYANSNQLTSIPATL--PDTIQEMELSINRITE--------L 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 381 PETamtLPSearvnihaiaTLKLLDYSDKQATLIPDDLFDATKTtlitsINFSKNQLCEIPQrivELKEMVLDINLSFNK 460
Cdd:PRK15370 257 PER---LPS----------ALQSLDLFHNKISCLPENLPEELRY-----LSVYDNSIRTLPA---HLPSGITHLNVQSNS 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 461 LSFISHELCLlqKLTFLDLRNNFLSSLPEEMSSltKLQTINLSFNRFKVFPEVLyrISTLEAVLISNNQVGSVdPQkmKL 540
Cdd:PRK15370 316 LTALPETLPP--GLKTLEAGENALTSLPASLPP--ELQVLDVSKNQITVLPETL--PPTITTLDVSRNALTNL-PE--NL 386
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 31541911 541 MENLNTLDLQNNDLLQIPPEL----GNCVQLRTLLLDGNPF 577
Cdd:PRK15370 387 PAALQIMQASRNNLVRLPESLphfrGEGPQPTRIIVEYNPF 427
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
101-317 |
8.22e-09 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 57.88 E-value: 8.22e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 101 LRLLPALTVLDIHDNQLT-----SLPSAIRELDNLQKLNVSHNKL-----KILPEEITSLKNLRTLHLQHNELT-----C 165
Cdd:COG5238 232 LKGNKSLTTLDLSNNQIGdegviALAEALKNNTTVETLYLSGNQIgaegaIALAKALQGNTTLTSLDLSVNRIGdegaiA 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 166 IPEGFEHLSCLEDLDLSSNRLATVPADFallssllrlnlssnqlknLPAEISRMKRLKHLDCDANLLetvppdvgSMESL 245
Cdd:COG5238 312 LAEGLQGNKTLHTLNLAYNGIGAQGAIA------------------LAKALQENTTLHSLDLSDNQI--------GDEGA 365
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 31541911 246 ELL--YLRRNKlrvlpefpscrQLKELHLAENQIEKLGAEHL-QHLQAILV--LDLRGNKLRSVPEEmALLQSLERL 317
Cdd:COG5238 366 IALakYLEGNT-----------TLRELNLGKNNIGKQGAEALiDALQTNRLhtLILDGNLIGAEAQQ-RLEQLLERI 430
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
414-580 |
1.39e-08 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 57.94 E-value: 1.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 414 IPDDLFdaTKTTLITSINFSKNQLC-EIPQRIVELKEMvldINLSFNKLSF-ISHELCLLQKLTFLDLRNNFLSS-LPEE 490
Cdd:PLN00113 109 IPDDIF--TTSSSLRYLNLSNNNFTgSIPRGSIPNLET---LDLSNNMLSGeIPNDIGSFSSLKVLDLGGNVLVGkIPNS 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 491 MSSLTKLQTINLSFNRF-KVFPEVLYRISTLEAVLISNNQVGSVDPQKMKLMENLNTLDLQNNDLL-QIPPELGNCVQLR 568
Cdd:PLN00113 184 LTNLTSLEFLTLASNQLvGQIPRELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTgPIPSSLGNLKNLQ 263
|
170
....*....|..
gi 31541911 569 TLLLDGNPFRVP 580
Cdd:PLN00113 264 YLFLYQNKLSGP 275
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
101-368 |
1.52e-08 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 56.59 E-value: 1.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 101 LRLLPALTVLDIHDNQLTS-----LPSAIRELDNLQKLNVSHNK-------LKILPEEITSLKNLRTLHLQHNELTC--- 165
Cdd:cd00116 19 LPKLLCLQVLRLEGNTLGEeaakaLASALRPQPSLKELCLSLNEtgriprgLQSLLQGLTKGCGLQELDLSDNALGPdgc 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 166 -IPEGFEHLSCLEDLDLSSNRLATVPADFallssllrlnlSSNQLKNLPAeisrmkRLKHLDCDANLLEtvppdVGSMES 244
Cdd:cd00116 99 gVLESLLRSSSLQELKLNNNGLGDRGLRL-----------LAKGLKDLPP------ALEKLVLGRNRLE-----GASCEA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 245 LELlylrrnklrvlpEFPSCRQLKELHLAENQIEKLGAEHL----QHLQAILVLDLRGNKLRS-----VPEEMALLQSLE 315
Cdd:cd00116 157 LAK------------ALRANRDLKELNLANNGIGDAGIRALaeglKANCNLEVLDLNNNGLTDegasaLAETLASLKSLE 224
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 316 RLDLSNNDISSLPCS-------LGNLHLKFLALEGNplrtirrEIIAKGTQEVLKYLRSK 368
Cdd:cd00116 225 VLNLGDNNLTDAGAAalasallSPNISLLTLSLSCN-------DITDDGAKDLAEVLAEK 277
|
|
| PLN03210 |
PLN03210 |
Resistant to P. syringae 6; Provisional |
103-342 |
2.15e-08 |
|
Resistant to P. syringae 6; Provisional
Pssm-ID: 215633 [Multi-domain] Cd Length: 1153 Bit Score: 57.58 E-value: 2.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 103 LLPALTVLDIHDNQLTSLPSAIRElDNLQKLNVSHNKLKILPEEITSLKNLRTLHLQHNE-LTCIPEgFEHLSCLEDLDL 181
Cdd:PLN03210 587 LPPKLRLLRWDKYPLRCMPSNFRP-ENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSKnLKEIPD-LSMATNLETLKL 664
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 182 SSnrlatvpadfallssllrlnlsSNQLKNLPAEISRMKRLKHLD---CDAnlLETVPPDVgSMESLELLYLRR-NKLRV 257
Cdd:PLN03210 665 SD----------------------CSSLVELPSSIQYLNKLEDLDmsrCEN--LEILPTGI-NLKSLYRLNLSGcSRLKS 719
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 258 LPEFPScrQLKELHLAENQIEKLGAE-HLQHLQAILVLDLRGNKL--RSVPEE--MALLQ-SLERLDLSNN-DISSLPCS 330
Cdd:PLN03210 720 FPDIST--NISWLDLDETAIEEFPSNlRLENLDELILCEMKSEKLweRVQPLTplMTMLSpSLTRLFLSDIpSLVELPSS 797
|
250
....*....|...
gi 31541911 331 LGNLH-LKFLALE 342
Cdd:PLN03210 798 IQNLHkLEHLEIE 810
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
129-186 |
6.84e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 49.45 E-value: 6.84e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 129 NLQKLNVSHNKLKILPEEI-TSLKNLRTLHLQHNELTCI-PEGFEHLSCLEDLDLSSNRL 186
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
82-301 |
1.04e-07 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 55.17 E-value: 1.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 82 TDLTKLIISSNKLQSLSddlRLLPALTVLDIHDNQLTSLPSAIRELDNLQKLNvshNKLKILPeeitslknlrtlhlqhn 161
Cdd:PRK15387 282 SGLCKLWIFGNQLTSLP---VLPPGLQELSVSDNQLASLPALPSELCKLWAYN---NQLTSLP----------------- 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 162 eltCIPEGfehlscLEDLDLSSNRLATVPADFALLSSLLRLNLSSNQLKNLPAEisrmkrLKHLDCDANLLETVPpdVGS 241
Cdd:PRK15387 339 ---TLPSG------LQELSVSDNQLASLPTLPSELYKLWAYNNRLTSLPALPSG------LKELIVSGNRLTSLP--VLP 401
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 242 MESLELLyLRRNKLRVLPEFPScrQLKELHLAENQIEKLgAEHLQHLQAILVLDLRGNKL 301
Cdd:PRK15387 402 SELKELM-VSGNRLTSLPMLPS--GLLSLSVYRNQLTRL-PESLIHLSSETTVNLEGNPL 457
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
105-163 |
1.72e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.29 E-value: 1.72e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 31541911 105 PALTVLDIHDNQLTSL-PSAIRELDNLQKLNVSHNKLKIL-PEEITSLKNLRTLHLQHNEL 163
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
265-324 |
2.01e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.90 E-value: 2.01e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 31541911 265 RQLKELHLAENQIEKLGAEHLQHLQAILVLDLRGNKLRSV-PEEMALLQSLERLDLSNNDI 324
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
83-173 |
4.87e-07 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 52.78 E-value: 4.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 83 DLTKLIISSNKLQSLSDDLRllPALTVLDIHDNQLTSLPSAIREldNLQKLNVSHNKLKILPEEITSLknLRTLHLQHNE 162
Cdd:PRK15370 326 GLKTLEAGENALTSLPASLP--PELQVLDVSKNQITVLPETLPP--TITTLDVSRNALTNLPENLPAA--LQIMQASRNN 399
|
90
....*....|.
gi 31541911 163 LTCIPEGFEHL 173
Cdd:PRK15370 400 LVRLPESLPHF 410
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
84-140 |
6.15e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 46.75 E-value: 6.15e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 31541911 84 LTKLIISSNKLQSLSDD-LRLLPALTVLDIHDNQLTSL-PSAIRELDNLQKLNVSHNKL 140
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGaFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
120-191 |
1.02e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 48.66 E-value: 1.02e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 31541911 120 LPSAIRELDNLQKLNVSHNKLK-ILPEEITSLKNLRTLHLQHNELT-CIPEGFEHLSCLEDLDLSSNRLA-TVPA 191
Cdd:PLN03150 434 IPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLSgRVPA 508
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
244-301 |
3.79e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 41.74 E-value: 3.79e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 244 SLELLYLRRNKLRVLPE--FPSCRQLKELHLAENQIEKLGAEHLQHLQAILVLDLRGNKL 301
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
248-505 |
4.56e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 45.16 E-value: 4.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 248 LYLRRNKLRVLPEFPSCRQLKELHLAENQIEKLgaEHLQHLQAILVLDLRGNKLRSVpEEMALLQSLERLDLSNNDISSL 327
Cdd:cd21340 7 LYLNDKNITKIDNLSLCKNLKVLYLYDNKITKI--ENLEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 328 pCSLGNLH-LKFLALEgnplrtirreiiakgtqevlkylrskikddrtNQNDSvPETAMTLPSEArvnIHAIA-TLKLLd 405
Cdd:cd21340 84 -EGLENLTnLEELHIE--------------------------------NQRLP-PGEKLTFDPRS---LAALSnSLRVL- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 406 ysdkqatlipddlfdatkttlitsinfsknqlceipqrivelkemvldiNLSFNKLSFIShELCLLQKLTFLDLRNNFLS 485
Cdd:cd21340 126 -------------------------------------------------NISGNNIDSLE-PLAPLRNLEQLDASNNQIS 155
|
250 260
....*....|....*....|...
gi 31541911 486 SLPE---EMSSLTKLQTINLSFN 505
Cdd:cd21340 156 DLEElldLLSSWPSLRELDLTGN 178
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
451-587 |
6.41e-05 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 45.99 E-value: 6.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 451 VLDINLSFNKLSF-ISHELCLLQKLTFLDLRNNFLS-SLPEEMSSLT-KLQTINLSFNRFKvFPEVLYRISTLEAVLISN 527
Cdd:PLN00113 71 VVSIDLSGKNISGkISSAIFRLPYIQTINLSNNQLSgPIPDDIFTTSsSLRYLNLSNNNFT-GSIPRGSIPNLETLDLSN 149
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 31541911 528 NQVGSVDPQKMKLMENLNTLDLQNNDLL-QIPPELGNCVQLRTLLLDGNPF--RVPRAAILMK 587
Cdd:PLN00113 150 NMLSGEIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLvgQIPRELGQMK 212
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
459-577 |
7.92e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 44.39 E-value: 7.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 459 NKLSFISHeLCLLQKLTFLDLRNNFLSSLpEEMSSLTKLQTINLSFNRFKVFpEVLYRISTLE----------------- 521
Cdd:cd21340 34 NKITKIEN-LEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV-EGLENLTNLEelhienqrlppgekltf 110
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 31541911 522 ------------AVL-ISNNQVGSVDPqkMKLMENLNTLDLQNN---DLLQIPPELGNCVQLRTLLLDGNPF 577
Cdd:cd21340 111 dprslaalsnslRVLnISGNNIDSLEP--LAPLRNLEQLDASNNqisDLEELLDLLSSWPSLRELDLTGNPV 180
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
477-582 |
8.21e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 45.58 E-value: 8.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 477 LDLRNNFLSS-LPEEMSSLTKLQTINLSFNRFKvfpevlyristleavlisnnqvGSVdPQKMKLMENLNTLDLQNNDLL 555
Cdd:PLN03150 423 LGLDNQGLRGfIPNDISKLRHLQSINLSGNSIR----------------------GNI-PPSLGSITSLEVLDLSYNSFN 479
|
90 100 110
....*....|....*....|....*....|
gi 31541911 556 -QIPPELGNCVQLRTLLLDGNPF--RVPRA 582
Cdd:PLN03150 480 gSIPESLGQLTSLRILNLNGNSLsgRVPAA 509
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
260-336 |
1.44e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 44.81 E-value: 1.44e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 31541911 260 EFPSCRQLKELHLAENQIEKLGAEHLQHLQAILVLDLRGNKLR-SVPEEMALLQSLERLDLSNNDISS-LPCSLGNLHL 336
Cdd:PLN03150 437 DISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLSGrVPAALGGRLL 515
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
266-360 |
1.85e-04 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 44.40 E-value: 1.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 266 QLKELHLAENQIEKLGA----EHLQHLQAILVLDLRGNKLrSVPEEMALLQSL------ERLDLSNNDIS-----SLPCS 330
Cdd:COG5238 209 TVTTLWLKRNPIGDEGAeilaEALKGNKSLTTLDLSNNQI-GDEGVIALAEALknnttvETLYLSGNQIGaegaiALAKA 287
|
90 100 110
....*....|....*....|....*....|.
gi 31541911 331 L-GNLHLKFLALEGNPLRTIRREIIAKGTQE 360
Cdd:COG5238 288 LqGNTTLTSLDLSVNRIGDEGAIALAEGLQG 318
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
82-186 |
2.37e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 43.50 E-value: 2.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 82 TDLTKLIISSNKL-----QSLSDDLRLLPALTVLDIHDNQLTS-----LPSAIRELDNLQKLNVSHNKL------KILPE 145
Cdd:cd00116 165 RDLKELNLANNGIgdagiRALAEGLKANCNLEVLDLNNNGLTDegasaLAETLASLKSLEVLNLGDNNLtdagaaALASA 244
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 31541911 146 EITSLKNLRTLHLQHNELTCipEGFEHLS-------CLEDLDLSSNRL 186
Cdd:cd00116 245 LLSPNISLLTLSLSCNDITD--DGAKDLAevlaekeSLLELDLRGNKF 290
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
82-187 |
4.36e-04 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 43.23 E-value: 4.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 82 TDLTKLIISSNKLQSLSddlRLLPALTVLDIHDNQLTSLPSAIRELdnlQKLNVSHNKLKILPEEITSLknlRTLHLQHN 161
Cdd:PRK15387 362 SELYKLWAYNNRLTSLP---ALPSGLKELIVSGNRLTSLPVLPSEL---KELMVSGNRLTSLPMLPSGL---LSLSVYRN 432
|
90 100
....*....|....*....|....*.
gi 31541911 162 ELTCIPEGFEHLSCLEDLDLSSNRLA 187
Cdd:PRK15387 433 QLTRLPESLIHLSSETTVNLEGNPLS 458
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
248-505 |
1.57e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 40.80 E-value: 1.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 248 LYLRRNKL---RVLPEFPSCRQLKELHLAENQIEKLG----AEHLQHLQAILVLDLRGNKLRSVPEEMALLQS------- 313
Cdd:cd00116 3 LSLKGELLkteRATELLPKLLCLQVLRLEGNTLGEEAakalASALRPQPSLKELCLSLNETGRIPRGLQSLLQgltkgcg 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 314 LERLDLSNNDISSLPC----------SLGNLHLKFLALEGNPLRtirreIIAKGTQEVLKYLRSKIKDDRTNQNDSVPET 383
Cdd:cd00116 83 LQELDLSDNALGPDGCgvlesllrssSLQELKLNNNGLGDRGLR-----LLAKGLKDLPPALEKLVLGRNRLEGASCEAL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 384 AMTLPsearvnihAIATLKLLDYSDKQatlIPDDLFDAtkttlitsinfsknqLCEIPQRIVELKEMVLDiNLSFNKL-- 461
Cdd:cd00116 158 AKALR--------ANRDLKELNLANNG---IGDAGIRA---------------LAEGLKANCNLEVLDLN-NNGLTDEga 210
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 31541911 462 SFISHELCLLQKLTFLDLRNNFLSS------LPEEMSSLTKLQTINLSFN 505
Cdd:cd00116 211 SALAETLASLKSLEVLNLGDNNLTDagaaalASALLSPNISLLTLSLSCN 260
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
454-507 |
1.74e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 37.12 E-value: 1.74e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 31541911 454 INLSFNKLSFISHELCL-LQKLTFLDLRNNFLSSL-PEEMSSLTKLQTINLSFNRF 507
Cdd:pfam13855 6 LDLSNNRLTSLDDGAFKgLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
518-577 |
2.68e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 36.35 E-value: 2.68e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 31541911 518 STLEAVLISNNQVGSVDPQKMKLMENLNTLDLQNNDLLQIPPE-LGNCVQLRTLLLDGNPF 577
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
221-277 |
8.58e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 35.19 E-value: 8.58e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 31541911 221 RLKHLDCDANLLETVPPDV-GSMESLELLYLRRNKLRVLPE--FPSCRQLKELHLAENQI 277
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
|
|
| |
