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Conserved domains on  [gi|224967112|ref|NP_112441|]
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coagulation factor XIII B chain precursor [Mus musculus]

Protein Classification

CCP domain-containing protein( domain architecture ID 13332024)

CCP domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 165-452 5.46e-28

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 113.59  E-value: 5.46e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 165 STTQRTFKVKDIVAYTCTAGYYTttgKQTGE--AECQANGWSLTPQCNKLMCSSLRLIENGYFHPVKQTYeeGDVVQFFC 242
Cdd:PHA02927  38 TDANANYNIGDTIEYLCLPGYRK---QKMGPiyAKCTGTGWTLFNQCIKRRCPSPRDIDNGQLDIGGVDF--GSSITYSC 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 243 HENYYLSGSDLIQCY-----NFGWYPESPICEgrrnrcppppvplnskiqphsttyrhgervhiecelnfviqgseellc 317
Cdd:PHA02927 113 NSGYQLIGESKSYCElgstgSMVWNPEAPICE------------------------------------------------ 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 318 engkwteppkcieekeKVACEQPPSVENGVAHPHSEIYYSGDKVTYRCGGGYSLRGSSTITCNRGRWTLPPECveNIENC 397
Cdd:PHA02927 145 ----------------SVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTC--QIVKC 206

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112 398 kPPPDIANGVVVDGLLASYTTGSSVEYRCNEYYLLKGSETSRCEQGAWSSP--PVCL 452
Cdd:PHA02927 207 -PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKCV 262
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 51-268 1.36e-13

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 71.22  E-value: 1.36e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112  51 SVDKKLSFFCLAGYATESgKQEEQIRCTAEGWSPNPRCYK-KCLKP-DLRNGYVSNDKVlyKLQERMSYGCSSGYKTTGG 128
Cdd:PHA02927  45 NIGDTIEYLCLPGYRKQK-MGPIYAKCTGTGWTLFNQCIKrRCPSPrDIDNGQLDIGGV--DFGSSITYSCNSGYQLIGE 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 129 KDE--EVVHCLSAGWSSQ-PSCrkEQETC-LAPELEHGNYSTTQRTFKVKDIVAYTCTAGyYTTTGKQTgeAECQANGWS 204
Cdd:PHA02927 122 SKSycELGSTGSMVWNPEaPIC--ESVKCqSPPSISNGRHNGYEDFYTDGSVVTYSCNSG-YSLIGNSG--VLCSGGEWS 196

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 224967112 205 LTPQCNKLMCSSlRLIENGYFHP-VKQTYEEGDVVQFFCHENYYLSGSDLIQCY-NFGWYPESPIC 268
Cdd:PHA02927 197 DPPTCQIVKCPH-PTISNGYLSSgFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSpGNTWQPELPKC 261
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 275-329 3.24e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 59.01  E-value: 3.24e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112 275 CPPPPVPLNSKIQPHSTTYRHGERVHIECELNFVIQGSEELLC-ENGKWT-EPPKCI 329
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSpPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 525-579 1.00e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 51.69  E-value: 1.00e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112 525 CASPPVIRNGDIVSSAArTYENGSSVEYRCFDNHFLQGSQNVYCV-DGVWT-TPPSC 579
Cdd:cd00033    1 CPPPPVPENGTVTGSKG-SYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 165-452 5.46e-28

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 113.59  E-value: 5.46e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 165 STTQRTFKVKDIVAYTCTAGYYTttgKQTGE--AECQANGWSLTPQCNKLMCSSLRLIENGYFHPVKQTYeeGDVVQFFC 242
Cdd:PHA02927  38 TDANANYNIGDTIEYLCLPGYRK---QKMGPiyAKCTGTGWTLFNQCIKRRCPSPRDIDNGQLDIGGVDF--GSSITYSC 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 243 HENYYLSGSDLIQCY-----NFGWYPESPICEgrrnrcppppvplnskiqphsttyrhgervhiecelnfviqgseellc 317
Cdd:PHA02927 113 NSGYQLIGESKSYCElgstgSMVWNPEAPICE------------------------------------------------ 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 318 engkwteppkcieekeKVACEQPPSVENGVAHPHSEIYYSGDKVTYRCGGGYSLRGSSTITCNRGRWTLPPECveNIENC 397
Cdd:PHA02927 145 ----------------SVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTC--QIVKC 206

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112 398 kPPPDIANGVVVDGLLASYTTGSSVEYRCNEYYLLKGSETSRCEQGAWSSP--PVCL 452
Cdd:PHA02927 207 -PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 51-268 1.36e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 71.22  E-value: 1.36e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112  51 SVDKKLSFFCLAGYATESgKQEEQIRCTAEGWSPNPRCYK-KCLKP-DLRNGYVSNDKVlyKLQERMSYGCSSGYKTTGG 128
Cdd:PHA02927  45 NIGDTIEYLCLPGYRKQK-MGPIYAKCTGTGWTLFNQCIKrRCPSPrDIDNGQLDIGGV--DFGSSITYSCNSGYQLIGE 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 129 KDE--EVVHCLSAGWSSQ-PSCrkEQETC-LAPELEHGNYSTTQRTFKVKDIVAYTCTAGyYTTTGKQTgeAECQANGWS 204
Cdd:PHA02927 122 SKSycELGSTGSMVWNPEaPIC--ESVKCqSPPSISNGRHNGYEDFYTDGSVVTYSCNSG-YSLIGNSG--VLCSGGEWS 196

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 224967112 205 LTPQCNKLMCSSlRLIENGYFHP-VKQTYEEGDVVQFFCHENYYLSGSDLIQCY-NFGWYPESPIC 268
Cdd:PHA02927 197 DPPTCQIVKCPH-PTISNGYLSSgFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSpGNTWQPELPKC 261
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 275-329 3.24e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 59.01  E-value: 3.24e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112 275 CPPPPVPLNSKIQPHSTTYRHGERVHIECELNFVIQGSEELLC-ENGKWT-EPPKCI 329
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 214-268 4.74e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 58.31  E-value: 4.74e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 224967112   214 CSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPIC 268
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGtWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 397-451 8.04e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 57.86  E-value: 8.04e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112 397 CKPPPDIANGVVVdGLLASYTTGSSVEYRCNEYYLLKGSETSRC-EQGAWS-SPPVC 451
Cdd:cd00033    1 CPPPPVPENGTVT-GSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSpPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 275-328 4.95e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 55.61  E-value: 4.95e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 224967112   275 CPPPPVPLNSKIQPHSTTYRHGERVHIECELNFVIQGSEELLC-ENGKWT-EPPKC 328
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
337-390 1.68e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 54.04  E-value: 1.68e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 224967112  337 CEQPPSVENGVAHPHSEIYYSGDKVTYRCGGGYSLRGSSTITC-NRGRWTLP-PEC 390
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCqEDGTWSPPfPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 525-579 1.00e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 51.69  E-value: 1.00e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112 525 CASPPVIRNGDIVSSAArTYENGSSVEYRCFDNHFLQGSQNVYCV-DGVWT-TPPSC 579
Cdd:cd00033    1 CPPPPVPENGTVTGSKG-SYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
275-328 1.11e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.65  E-value: 1.11e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 224967112  275 CPPPPVPLNSKIQPHSTTYRHGERVHIECELNFVIQGSEELLC-ENGKWT-EPPKC 328
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCqEDGTWSpPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 525-579 7.10e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 46.37  E-value: 7.10e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112   525 CASPPVIRNGDIVSSAaRTYENGSSVEYRCFDNHFLQGSQNVYCV-DGVWT-TPPSC 579
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
525-579 4.05e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 38.63  E-value: 4.05e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112  525 CASPPVIRNGDIVSSAARtYENGSSVEYRCFDNHFLQGSQNVYCV-DGVWT-TPPSC 579
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNE-YNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 95-148 5.68e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 35.52  E-value: 5.68e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 224967112  95 PDLRNGYVSNDKVLYKLQERMSYGCSSGYKTTGgkdEEVVHCLSAG-WS-SQPSCR 148
Cdd:cd00033    5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVG---SSTITCTENGgWSpPPPTCE 57
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 165-452 5.46e-28

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 113.59  E-value: 5.46e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 165 STTQRTFKVKDIVAYTCTAGYYTttgKQTGE--AECQANGWSLTPQCNKLMCSSLRLIENGYFHPVKQTYeeGDVVQFFC 242
Cdd:PHA02927  38 TDANANYNIGDTIEYLCLPGYRK---QKMGPiyAKCTGTGWTLFNQCIKRRCPSPRDIDNGQLDIGGVDF--GSSITYSC 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 243 HENYYLSGSDLIQCY-----NFGWYPESPICEgrrnrcppppvplnskiqphsttyrhgervhiecelnfviqgseellc 317
Cdd:PHA02927 113 NSGYQLIGESKSYCElgstgSMVWNPEAPICE------------------------------------------------ 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 318 engkwteppkcieekeKVACEQPPSVENGVAHPHSEIYYSGDKVTYRCGGGYSLRGSSTITCNRGRWTLPPECveNIENC 397
Cdd:PHA02927 145 ----------------SVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTC--QIVKC 206

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112 398 kPPPDIANGVVVDGLLASYTTGSSVEYRCNEYYLLKGSETSRCEQGAWSSP--PVCL 452
Cdd:PHA02927 207 -PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKCV 262
PHA02831 PHA02831
EEV host range protein; Provisional
 230-402 5.56e-15

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 75.41  E-value: 5.56e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 230 QTYEEGDVVQFFCHENYylsGSDLIQCYNFGWYPESpICEGRRNrCPPPPVPLNSKIQPHSTTYRHGERVHIECELN--- 306
Cdd:PHA02831  38 KVYEENENLEYKCNNNF---DKVFVTCNNGSWSTKN-MCIGKRN-CKDPVTILNGYIKNKKDQYSFGDSVTYACKVNkle 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 307 -FVIQGSEELLCENGKWT-EPPKCieekEKVACEQPpSVENGVAHPHSEIYYSGDKVTYRCGGGYSLRGSSTITCNRGRW 384
Cdd:PHA02831 113 kYSIVGNETVKCINKQWVpKYPVC----KLIRCKYP-ALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSI 187

                        170       180
                 ....*....|....*....|
gi 224967112 385 TLP--PECVENIENCKPPPD 402
Cdd:PHA02831 188 WYPgiPKCVKDKVHNEIQPN 207
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 153-402 6.38e-14

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 73.20  E-value: 6.38e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 153 TCLAPELEHGNYSTTQRTFKVKDIVAYTCTAGYYTTTGKqtgeAECQANGWSLTPQCNKlMCSSLRLIENGYFHPVKQTY 232
Cdd:PHA02954  20 TCTVPTMNNAKLTSTETSFNDKQKVTFTCDSGYYSLDPN----AVCETDKWKYENPCKK-MCTVSDYVSELYDKPLYEVN 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 233 E------EGDVVQFFCHE-NYYLSGSDLIQCYNfgwypespicegrrNRCPPPPVPLNSkIQPHSTTYRHGERVHIECEL 305
Cdd:PHA02954  95 StitlicKDETKYFRCEEkNGNTSWNDTVTCPN--------------AECQPLQLEHGS-CQPVKEKYSFGEHITINCDV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 306 NFVIQGSEELLCENGKWTEPPKCIEEkekvaCEQpPSVENGVAhpHSEIYYSGDKVTYRCGGGYSLRGSSTITCNRGRWT 385
Cdd:PHA02954 160 GYEVIGASYISCTANSWNVIPSCQQK-----CDI-PSLSNGLI--SGSTFSIGGVIHLSCKSGFTLTGSPSSTCIDGKWN 231

                        250
                 ....*....|....*...
gi 224967112 386 -LPPECVENIENCKPPPD 402
Cdd:PHA02954 232 pVLPICVRSNEEFDPVDD 249
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 51-268 1.36e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 71.22  E-value: 1.36e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112  51 SVDKKLSFFCLAGYATESgKQEEQIRCTAEGWSPNPRCYK-KCLKP-DLRNGYVSNDKVlyKLQERMSYGCSSGYKTTGG 128
Cdd:PHA02927  45 NIGDTIEYLCLPGYRKQK-MGPIYAKCTGTGWTLFNQCIKrRCPSPrDIDNGQLDIGGV--DFGSSITYSCNSGYQLIGE 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 129 KDE--EVVHCLSAGWSSQ-PSCrkEQETC-LAPELEHGNYSTTQRTFKVKDIVAYTCTAGyYTTTGKQTgeAECQANGWS 204
Cdd:PHA02927 122 SKSycELGSTGSMVWNPEaPIC--ESVKCqSPPSISNGRHNGYEDFYTDGSVVTYSCNSG-YSLIGNSG--VLCSGGEWS 196

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 224967112 205 LTPQCNKLMCSSlRLIENGYFHP-VKQTYEEGDVVQFFCHENYYLSGSDLIQCY-NFGWYPESPIC 268
Cdd:PHA02927 197 DPPTCQIVKCPH-PTISNGYLSSgFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSpGNTWQPELPKC 261
PHA02639 PHA02639
EEV host range protein; Provisional
 212-403 1.91e-13

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 71.62  E-value: 1.91e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 212 LMCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCY----NFGWYPESPICEGRrnRCPPPPVPLNSKIQ 287
Cdd:PHA02639  20 IYCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIkdknNAIWSNKAPFCMLK--ECNDPPSIINGKIY 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 288 PHSTTYRHGERVHIECE----LNFVIQGSEELLCENGK-WT-EPPKCieekEKVACeQPPSVENGVAH--PHSEIYYSGD 359
Cdd:PHA02639  98 NKREMYKVGDEIYYVCNehkgVQYSLVGNEKITCIQDKsWKpDPPIC----KMINC-RFPALQNGYINgiPSNKKFYYKT 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 224967112 360 KVTYRCGGGYSLRGSSTITCNRGRWTLP--PECVENiencKPPPDI 403
Cdd:PHA02639 173 RVGFSCKSGFDLVGEKYSTCNINATWFPsiPTCVRN----KPIDDI 214
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 275-580 1.21e-12

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 68.53  E-value: 1.21e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 275 CPPPPVPLNSKIQ-----PHSTTYRHGERVHIECELNFVIQ--GSEELLCENGKWTEPPKCIEEKekvaCEQPPSVENGV 347
Cdd:PHA02927  21 CTIPSRPINMKFKnsvetDANANYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCIKRR----CPSPRDIDNGQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 348 AHPHSEIYysGDKVTYRCGGGYSLRGSSTITCNRGR-----WTLPPECVENIEnCKPPPDIANGVVvDGLLASYTTGSSV 422
Cdd:PHA02927  97 LDIGGVDF--GSSITYSCNSGYQLIGESKSYCELGStgsmvWNPEAPICESVK-CQSPPSISNGRH-NGYEDFYTDGSVV 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 423 EYRCNEYYLLKGSETSRCEQGAWSSPPVClepctidvdhmnrnniQLkwkyegkilhgdlidfvckqgynlspsiplsei 502
Cdd:PHA02927 173 TYSCNSGYSLIGNSGVLCSGGEWSDPPTC----------------QI--------------------------------- 203

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 503 saqcnrgdVRYPMcirkeskgmcaspPVIRNGDIVSSAARTYENGSSVEYRCFDNHFLQGSQNVYCVDGVWTTP--PSCL 580
Cdd:PHA02927 204 --------VKCPH-------------PTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKCV 262
PHA02831 PHA02831
EEV host range protein; Provisional
 353-514 3.96e-12

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 66.94  E-value: 3.96e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 353 EIYYSGDKVTYRCGGGYSlrgSSTITCNRGRWTLPPECVENiENCKPPPDIANGVVVDGLlASYTTGSSVEYRCN----E 428
Cdd:PHA02831  38 KVYEENENLEYKCNNNFD---KVFVTCNNGSWSTKNMCIGK-RNCKDPVTILNGYIKNKK-DQYSFGDSVTYACKvnklE 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 429 YYLLKGSETSRCEQGAW-SSPPVCLepcTIDVDHMNRNNIQLKwKYEGKILHGDLIDFVCKQGYNLSPSiplseISAQCN 507
Cdd:PHA02831 113 KYSIVGNETVKCINKQWvPKYPVCK---LIRCKYPALQNGFLN-VFEKKFYYGDIVNFKCKKGFILLGS-----SVSTCD 183


                 ....*..
gi 224967112 508 RGDVRYP 514
Cdd:PHA02831 184 INSIWYP 190
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 97-329 5.93e-12

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 66.60  E-value: 5.93e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112  97 LRNGYVSNDKVLYKLQERMSYGCSSGYKTTGgKDEEVVHCLSAGWSSQPSCRKEQetCLAP-ELEHGNYSTTQRTFKVKd 175
Cdd:PHA02927  32 FKNSVETDANANYNIGDTIEYLCLPGYRKQK-MGPIYAKCTGTGWTLFNQCIKRR--CPSPrDIDNGQLDIGGVDFGSS- 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 176 iVAYTCTAGYYTTtGKQTGEAECQANG---WS-LTPQCNKLMCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGS 251
Cdd:PHA02927 108 -ITYSCNSGYQLI-GESKSYCELGSTGsmvWNpEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGN 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 252 DLIQCYNFGWyPESPICEgrRNRCPPPPVPLNSKIQPHSTTYRHGERVHIECELNFVIQGSEELLCENGKWTEP--PKCI 329
Cdd:PHA02927 186 SGVLCSGGEW-SDPPTCQ--IVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 275-329 3.24e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 59.01  E-value: 3.24e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112 275 CPPPPVPLNSKIQPHSTTYRHGERVHIECELNFVIQGSEELLC-ENGKWT-EPPKCI 329
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 214-268 4.74e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 58.31  E-value: 4.74e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 224967112   214 CSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPIC 268
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGtWSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 102-268 7.03e-11

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 63.47  E-value: 7.03e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 102 VSNDKVLYKLQERMSYGCSSGYkttggkDEEVVHCLSAGWSSQPSCRKEQeTCLAP-ELEHGNYSTTQRTFKVKDIVAYT 180
Cdd:PHA02831  33 DSYENKVYEENENLEYKCNNNF------DKVFVTCNNGSWSTKNMCIGKR-NCKDPvTILNGYIKNKKDQYSFGDSVTYA 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 181 CTAG---YYTTTGKQTgeAECQANGW-SLTPQCNKLMCSSLRLiENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQC 256
Cdd:PHA02831 106 CKVNkleKYSIVGNET--VKCINKQWvPKYPVCKLIRCKYPAL-QNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTC 182

                        170
                 ....*....|...
gi 224967112 257 -YNFGWYPESPIC 268
Cdd:PHA02831 183 dINSIWYPGIPKC 195
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 397-451 8.04e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 57.86  E-value: 8.04e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112 397 CKPPPDIANGVVVdGLLASYTTGSSVEYRCNEYYLLKGSETSRC-EQGAWS-SPPVC 451
Cdd:cd00033    1 CPPPPVPENGTVT-GSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSpPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 89-334 8.06e-11

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 63.95  E-value: 8.06e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112  89 YKKCLKPDLRNGYVSNDKVLYKLQERMSYGCSSGYKTTggkDEEVVhCLSAGWSSQPSCRKeqeTCLAPELEHGNYSttQ 168
Cdd:PHA02954  18 YSTCTVPTMNNAKLTSTETSFNDKQKVTFTCDSGYYSL---DPNAV-CETDKWKYENPCKK---MCTVSDYVSELYD--K 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 169 RTFKVKDIVAYTCTAgyytTTGKQTGEAECQANGWSLTPQCNKLMCSSLRLiENGYFHPVKQTYEEGDVVQFFCHENYYL 248
Cdd:PHA02954  89 PLYEVNSTITLICKD----ETKYFRCEEKNGNTSWNDTVTCPNAECQPLQL-EHGSCQPVKEKYSFGEHITINCDVGYEV 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 249 SGSDLIQCYNFGWyPESPICEgrrNRCPPPPVPlNSKIQphSTTYRHGERVHIECELNFVIQGSEELLCENGKWTEP-PK 327
Cdd:PHA02954 164 IGASYISCTANSW-NVIPSCQ---QKCDIPSLS-NGLIS--GSTFSIGGVIHLSCKSGFTLTGSPSSTCIDGKWNPVlPI 236


                 ....*..
gi 224967112 328 CIEEKEK 334
Cdd:PHA02954 237 CVRSNEE 243
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 214-269 9.78e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 57.47  E-value: 9.78e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112 214 CSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCY-NFGWYPESPICE 269
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 337-391 1.05e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 57.47  E-value: 1.05e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112 337 CEQPPSVENGVAHPHSEIYYSGDKVTYRCGGGYSLRGSSTITCNR-GRWT-LPPECV 391
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEnGGWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 337-390 1.30e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.15  E-value: 1.30e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 224967112   337 CEQPPSVENGVAHPHSEIYYSGDKVTYRCGGGYSLRGSSTITC-NRGRWTLP-PEC 390
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPpPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 275-328 4.95e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 55.61  E-value: 4.95e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 224967112   275 CPPPPVPLNSKIQPHSTTYRHGERVHIECELNFVIQGSEELLC-ENGKWT-EPPKC 328
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
337-390 1.68e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 54.04  E-value: 1.68e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 224967112  337 CEQPPSVENGVAHPHSEIYYSGDKVTYRCGGGYSLRGSSTITC-NRGRWTLP-PEC 390
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCqEDGTWSPPfPEC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 209-330 3.02e-09

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 57.64  E-value: 3.02e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 209 CNKLMCSSLRLIENGYFHPVKQTYEEGDVVQFFCHEN-----YYLSGSDLIQCYNFG-WYPESPICEGRRNRCPPPPVPL 282
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGkWNKEFPVCKIIRCRFPALQNGF 98

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 224967112 283 NSKIqPHSTTYRHGERVHIECELNFVIQGSEELLCE-NGKW-TEPPKCIE 330
Cdd:PHA02817  99 VNGI-PDSKKFYYESEVSFSCKPGFVLIGTKYSVCGiNSSWiPKVPICSR 147
Sushi pfam00084
Sushi repeat (SCR repeat);
214-268 3.40e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.27  E-value: 3.40e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 224967112  214 CSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPIC 268
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGtWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 525-579 1.00e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 51.69  E-value: 1.00e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112 525 CASPPVIRNGDIVSSAArTYENGSSVEYRCFDNHFLQGSQNVYCV-DGVWT-TPPSC 579
Cdd:cd00033    1 CPPPPVPENGTVTGSKG-SYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 397-451 1.62e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.37  E-value: 1.62e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112   397 CKPPPDIANGVVVDGLlASYTTGSSVEYRCNEYYLLKGSETSRC-EQGAWS-SPPVC 451
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSpPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 275-458 2.93e-08

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 55.83  E-value: 2.93e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 275 CPPPPVPLNSKIQPHSTTYRHGERVHIECELNFVIQGSEELLC----ENGKWT-EPPKCIEEKekvaCEQPPSVENGVAH 349
Cdd:PHA02639  22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCikdkNNAIWSnKAPFCMLKE----CNDPPSIINGKIY 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 350 PHSEIYYSGDKVTYRC----GGGYSLRGSSTITCNRGRWTLPPECVENIENCKPPPdIANGvVVDGLLAS--YTTGSSVE 423
Cdd:PHA02639  98 NKREMYKVGDEIYYVCnehkGVQYSLVGNEKITCIQDKSWKPDPPICKMINCRFPA-LQNG-YINGIPSNkkFYYKTRVG 175

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 224967112 424 YRCNEYYLLKGSETSRCEQGA--WSSPPVCLEPCTID 458
Cdd:PHA02639 176 FSCKSGFDLVGEKYSTCNINAtwFPSIPTCVRNKPID 212
Sushi pfam00084
Sushi repeat (SCR repeat);
397-451 4.93e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 49.81  E-value: 4.93e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112  397 CKPPPDIANGVVVdGLLASYTTGSSVEYRCNEYYLLKGSETSRCEQ-GAWSSP-PVC 451
Cdd:pfam00084   1 CPPPPDIPNGKVS-ATKNEYNYGASVSYECDPGYRLVGSPTITCQEdGTWSPPfPEC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 337-467 6.23e-08

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 53.79  E-value: 6.23e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 337 CEQPPSVENGVAHPHSEIYYSGDKVTYRCGGG-----YSLRGSSTITCNR-GRWTL-PPECveNIENCKPPPdIANGvVV 409
Cdd:PHA02817  24 CCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKdGKWNKeFPVC--KIIRCRFPA-LQNG-FV 99

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 224967112 410 DGLLAS--YTTGSSVEYRCNEYYLLKGSETSRCEQGAWSSP--PVCLE-PCTIDVDHMNRNNI 467
Cdd:PHA02817 100 NGIPDSkkFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPkvPICSRdNITYNKIYINKVNI 162
Sushi pfam00084
Sushi repeat (SCR repeat);
275-328 1.11e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.65  E-value: 1.11e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 224967112  275 CPPPPVPLNSKIQPHSTTYRHGERVHIECELNFVIQGSEELLC-ENGKWT-EPPKC 328
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCqEDGTWSpPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 525-579 7.10e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 46.37  E-value: 7.10e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112   525 CASPPVIRNGDIVSSAaRTYENGSSVEYRCFDNHFLQGSQNVYCV-DGVWT-TPPSC 579
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 158-332 1.31e-05

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 47.74  E-value: 1.31e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 158 ELEHGNYSTTQRTFKVKDIVAYTCTAGYYTTTGKQTGEAECQANG-WS-LTPQCNKLMCSSLRLIENGYFHPVKQTYEEG 235
Cdd:PHA02639  27 DISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAiWSnKAPFCMLKECNDPPSIINGKIYNKREMYKVG 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112 236 DVVQFFCHEN----YYLSGSDLIQC-YNFGWYPESPICEGRRNRCPPPPVPLNSKIqPHSTTYRHGERVHIECELNFVIQ 310
Cdd:PHA02639 107 DEIYYVCNEHkgvqYSLVGNEKITCiQDKSWKPDPPICKMINCRFPALQNGYINGI-PSNKKFYYKTRVGFSCKSGFDLV 185

                        170       180
                 ....*....|....*....|....
gi 224967112 311 GSEELLCE-NGKW-TEPPKCIEEK 332
Cdd:PHA02639 186 GEKYSTCNiNATWfPSIPTCVRNK 209
PHA02831 PHA02831
EEV host range protein; Provisional
 75-185 1.33e-04

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 44.21  E-value: 1.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112  75 IRCTAEGWSPNPRCYKK--CLKP-DLRNGYVSNDKVLYKLQERMSYGCS----SGYKTTGgkdEEVVHCLSAGW-SSQPS 146
Cdd:PHA02831  59 VTCNNGSWSTKNMCIGKrnCKDPvTILNGYIKNKKDQYSFGDSVTYACKvnklEKYSIVG---NETVKCINKQWvPKYPV 135

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 224967112 147 CRKEQetCLAPELEHGNYSTTQRTFKVKDIVAYTCTAGY 185
Cdd:PHA02831 136 CKLIR--CKYPALQNGFLNVFEKKFYYGDIVNFKCKKGF 172
Sushi pfam00084
Sushi repeat (SCR repeat);
525-579 4.05e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 38.63  E-value: 4.05e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 224967112  525 CASPPVIRNGDIVSSAARtYENGSSVEYRCFDNHFLQGSQNVYCV-DGVWT-TPPSC 579
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNE-YNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 157-209 2.58e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 36.67  E-value: 2.58e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 224967112 157 PELEHGNYSTTQRTFKVKDIVAYTCTAGyYTTTGKQTgeAECQANG-WS-LTPQC 209
Cdd:cd00033    5 PVPENGTVTGSKGSYSYGSTVTYSCNEG-YTLVGSST--ITCTENGgWSpPPPTC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 90-185 4.48e-03

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 39.15  E-value: 4.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112  90 KKCLKPDLRNGYVSNDKVLYKLQERMSYGCSSG-----YKTTGgkdEEVVHCLSAG-WSSQPScRKEQETCLAPELEHG- 162
Cdd:PHA02817  23 KCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVG---EKNIICEKDGkWNKEFP-VCKIIRCRFPALQNGf 98

                         90       100
                 ....*....|....*....|....
gi 224967112 163 -NYSTTQRTFKVKDIVAYTCTAGY 185
Cdd:PHA02817  99 vNGIPDSKKFYYESEVSFSCKPGF 122
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 75-179 4.58e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 39.68  E-value: 4.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224967112  75 IRCTAEGWSPNPRCYKKCLKPDLRNGYVSNDKvlYKLQERMSYGCSSGYKTTGGKDEEvvhCLSAGWSS-QPSCRKEQET 153
Cdd:PHA02954 169 ISCTANSWNVIPSCQQKCDIPSLSNGLISGST--FSIGGVIHLSCKSGFTLTGSPSST---CIDGKWNPvLPICVRSNEE 243

                         90       100
                 ....*....|....*....|....*.
gi 224967112 154 clAPELEHGNYSTTQRTFKVKDIVAY 179
Cdd:PHA02954 244 --FDPVDDGPDDETDLSKLSKDVVQY 267
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 157-209 5.35e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 35.58  E-value: 5.35e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 224967112   157 PELEHGNYSTTQRTFKVKDIVAYTCTAGYYTTTGKqtgEAECQANG-WS-LTPQC 209
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSS---TITCLENGtWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 95-148 5.68e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 35.52  E-value: 5.68e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 224967112  95 PDLRNGYVSNDKVLYKLQERMSYGCSSGYKTTGgkdEEVVHCLSAG-WS-SQPSCR 148
Cdd:cd00033    5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVG---SSTITCTENGgWSpPPPTCE 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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