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Conserved domains on  [gi|30689902|ref|NP_174059|]
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translocase outer membrane 20-2 [Arabidopsis thaliana]

Protein Classification

mitochondrial import receptor subunit TOM20( domain architecture ID 12071239)

mitochondrial import receptor subunit TOM20 is a central component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins

CATH:  1.25.40.10
Gene Ontology:  GO:0006605|GO:0006886|GO:0005742
SCOP:  4001344

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TOM20_plant pfam06552
Plant specific mitochondrial import receptor subunit TOM20; This family consists of several ...
 8-201 7.67e-123

Plant specific mitochondrial import receptor subunit TOM20; This family consists of several plant specific mitochondrial import receptor subunit TOM20 (translocase of outer membrane 20 kDa subunit) proteins. Most mitochondrial proteins are encoded by the nuclear genome, and are synthesized in the cytosol. TOM20 is a general import receptor that binds to mitochondrial pre-sequences in the early step of protein import into the mitochondria.


:

Pssm-ID: 284068 [Multi-domain]  Cd Length: 187  Bit Score: 345.35  E-value: 7.67e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30689902     8 FERLIMFEHARKNSEAQYKNDPLDSENLLKWGGALLELSQFQPIPEAKLMLNDAISKLEEALTINPGKHQALWCIANAYT 87
Cdd:pfam06552   1 FDRLLFFEHARKDAEATYKNNPLDADNLTRWGGALLELSQFQPIPEAKQMIQDAISKLEEALTIDPKKHDALWCIGNAYT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30689902    88 AHAFYVHDPEEAKEHFDKATEYFQRAENEDPGNDTYRKSLDSSLKAPELHMQFMNQGMGQQILgggggggGGGMASSNVS 167
Cdd:pfam06552  81 SHAFLTPDPTEAKENFDKATQFFQQAVDEQPDNDLYRKSLEMAAKAPELHTEFHKQGLGQQIM-------GGEMASSSPS 153

                         170       180       190
                  ....*....|....*....|....*....|....
gi 30689902   168 QSSKKKKRNTEFTYDVCGWIILACGIVAWVGMAK 201
Cdd:pfam06552 154 QKSVKKKKSSDFKYDVMGWVILAIGVVAWISFAK 187
 
Name Accession Description Interval E-value
TOM20_plant pfam06552
Plant specific mitochondrial import receptor subunit TOM20; This family consists of several ...
 8-201 7.67e-123

Plant specific mitochondrial import receptor subunit TOM20; This family consists of several plant specific mitochondrial import receptor subunit TOM20 (translocase of outer membrane 20 kDa subunit) proteins. Most mitochondrial proteins are encoded by the nuclear genome, and are synthesized in the cytosol. TOM20 is a general import receptor that binds to mitochondrial pre-sequences in the early step of protein import into the mitochondria.


Pssm-ID: 284068 [Multi-domain]  Cd Length: 187  Bit Score: 345.35  E-value: 7.67e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30689902     8 FERLIMFEHARKNSEAQYKNDPLDSENLLKWGGALLELSQFQPIPEAKLMLNDAISKLEEALTINPGKHQALWCIANAYT 87
Cdd:pfam06552   1 FDRLLFFEHARKDAEATYKNNPLDADNLTRWGGALLELSQFQPIPEAKQMIQDAISKLEEALTIDPKKHDALWCIGNAYT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30689902    88 AHAFYVHDPEEAKEHFDKATEYFQRAENEDPGNDTYRKSLDSSLKAPELHMQFMNQGMGQQILgggggggGGGMASSNVS 167
Cdd:pfam06552  81 SHAFLTPDPTEAKENFDKATQFFQQAVDEQPDNDLYRKSLEMAAKAPELHTEFHKQGLGQQIM-------GGEMASSSPS 153

                         170       180       190
                  ....*....|....*....|....*....|....
gi 30689902   168 QSSKKKKRNTEFTYDVCGWIILACGIVAWVGMAK 201
Cdd:pfam06552 154 QKSVKKKKSSDFKYDVMGWVILAIGVVAWISFAK 187
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 25-124 4.11e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.92  E-value: 4.11e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30689902  25 YKNDPLDSENLLKWGGALLELSQFQpipeaklmlnDAISKLEEALTINPGKHQALWCIANAYtahafyvhdpeEAKEHFD 104
Cdd:COG4235  44 LRLDPDNADALLDLAEALLAAGDTE----------EAEELLERALALDPDNPEALYLLGLAA-----------FQQGDYA 102

                        90       100
                ....*....|....*....|
gi 30689902 105 KATEYFQRAENEDPGNDTYR 124
Cdd:COG4235 103 EAIAAWQKLLALLPADAPAR 122
ycf3 CHL00033
photosystem I assembly protein Ycf3
 67-120 2.81e-03

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 36.91  E-value: 2.81e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 30689902   67 EALTINPGKHQALWCIANAYtaH-----AFYVHDPEEAKEHFDKATEYFQRAENEDPGN 120
Cdd:CHL00033  97 QALERNPFLPQALNNMAVIC--HyrgeqAIEQGDSEIAEAWFDQAAEYWKQAIALAPGN 153
 
Name Accession Description Interval E-value
TOM20_plant pfam06552
Plant specific mitochondrial import receptor subunit TOM20; This family consists of several ...
 8-201 7.67e-123

Plant specific mitochondrial import receptor subunit TOM20; This family consists of several plant specific mitochondrial import receptor subunit TOM20 (translocase of outer membrane 20 kDa subunit) proteins. Most mitochondrial proteins are encoded by the nuclear genome, and are synthesized in the cytosol. TOM20 is a general import receptor that binds to mitochondrial pre-sequences in the early step of protein import into the mitochondria.


Pssm-ID: 284068 [Multi-domain]  Cd Length: 187  Bit Score: 345.35  E-value: 7.67e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30689902     8 FERLIMFEHARKNSEAQYKNDPLDSENLLKWGGALLELSQFQPIPEAKLMLNDAISKLEEALTINPGKHQALWCIANAYT 87
Cdd:pfam06552   1 FDRLLFFEHARKDAEATYKNNPLDADNLTRWGGALLELSQFQPIPEAKQMIQDAISKLEEALTIDPKKHDALWCIGNAYT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30689902    88 AHAFYVHDPEEAKEHFDKATEYFQRAENEDPGNDTYRKSLDSSLKAPELHMQFMNQGMGQQILgggggggGGGMASSNVS 167
Cdd:pfam06552  81 SHAFLTPDPTEAKENFDKATQFFQQAVDEQPDNDLYRKSLEMAAKAPELHTEFHKQGLGQQIM-------GGEMASSSPS 153

                         170       180       190
                  ....*....|....*....|....*....|....
gi 30689902   168 QSSKKKKRNTEFTYDVCGWIILACGIVAWVGMAK 201
Cdd:pfam06552 154 QKSVKKKKSSDFKYDVMGWVILAIGVVAWISFAK 187
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 25-124 4.11e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.92  E-value: 4.11e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30689902  25 YKNDPLDSENLLKWGGALLELSQFQpipeaklmlnDAISKLEEALTINPGKHQALWCIANAYtahafyvhdpeEAKEHFD 104
Cdd:COG4235  44 LRLDPDNADALLDLAEALLAAGDTE----------EAEELLERALALDPDNPEALYLLGLAA-----------FQQGDYA 102

                        90       100
                ....*....|....*....|
gi 30689902 105 KATEYFQRAENEDPGNDTYR 124
Cdd:COG4235 103 EAIAAWQKLLALLPADAPAR 122
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
14-108 1.07e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.92  E-value: 1.07e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30689902  14 FEHARKNSEAQYKNDPLDSENLLKWGGALLELSQFQpipeaklmlnDAISKLEEALTINPGKHQALWCIANAYtahaFYV 93
Cdd:COG0457  24 YEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYE----------EALADYEQALELDPDDAEALNNLGLAL----QAL 89

                        90
                ....*....|....*
gi 30689902  94 HDPEEAKEHFDKATE 108
Cdd:COG0457  90 GRYEEALEDYDKALE 104
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
28-120 1.38e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.53  E-value: 1.38e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30689902  28 DPLDSENLLKWGGALLELSQFQpipeaklmlnDAISKLEEALTINPGKHQALWCIANAYtahafyvhdpeEAKEHFDKAT 107
Cdd:COG0457   4 DPDDAEAYNNLGLAYRRLGRYE----------EAIEDYEKALELDPDDAEALYNLGLAY-----------LRLGRYEEAL 62

                        90
                ....*....|...
gi 30689902 108 EYFQRAENEDPGN 120
Cdd:COG0457  63 ADYEQALELDPDD 75
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 28-108 6.84e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 39.98  E-value: 6.84e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30689902  28 DPLDSENLLKWGGALLELSQFQpipeaklmlnDAISKLEEALTINPGKHQALWCIANAYTAHafyvHDPEEAKEHFDKAT 107
Cdd:COG3914 108 NPDNAEALFNLGNLLLALGRLE----------EALAALRRALALNPDFAEAYLNLGEALRRL----GRLEEAIAALRRAL 173


                .
gi 30689902 108 E 108
Cdd:COG3914 174 E 174
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
14-133 7.50e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.22  E-value: 7.50e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30689902  14 FEHARKNSEAQYKNDPLDSENLLKWGGALLELSQFQpipeaklmlnDAISKLEEALTINPGKHQALWCIANAYtahafyv 93
Cdd:COG0457  58 YEEALADYEQALELDPDDAEALNNLGLALQALGRYE----------EALEDYDKALELDPDDAEALYNLGLAL------- 120

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 30689902  94 hdpeEAKEHFDKATEYFQRAENEDPGNDTYRKSLDSSLKA 133
Cdd:COG0457 121 ----LELGRYDEAIEAYERALELDPDDADALYNLGIALEK 156
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 28-124 1.96e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 38.44  E-value: 1.96e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30689902  28 DPLDSENLLKWGGALLELSQFQpipeaklmlnDAISKLEEALTINPGKHQALWCIANAYtahaFYVHDPEEAKEHFDKAT 107
Cdd:COG3914 142 NPDFAEAYLNLGEALRRLGRLE----------EAIAALRRALELDPDNAEALNNLGNAL----QDLGRLEEAIAAYRRAL 207

                        90
                ....*....|....*..
gi 30689902 108 EYfqraeneDPGNDTYR 124
Cdd:COG3914 208 EL-------DPDNADAH 217
ycf3 CHL00033
photosystem I assembly protein Ycf3
 67-120 2.81e-03

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 36.91  E-value: 2.81e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 30689902   67 EALTINPGKHQALWCIANAYtaH-----AFYVHDPEEAKEHFDKATEYFQRAENEDPGN 120
Cdd:CHL00033  97 QALERNPFLPQALNNMAVIC--HyrgeqAIEQGDSEIAEAWFDQAAEYWKQAIALAPGN 153
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 41-124 3.98e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 37.40  E-value: 3.98e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30689902  41 ALLELSQFQpipEAKLMLNDAISKLEEALTINPGKHQALWCIANAYtahafyvhdpeEAKEHFDKATEYFQRAENEDPGN 120
Cdd:COG2956  78 ALLELAQDY---LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIY-----------EQEGDWEKAIEVLERLLKLGPEN 143


                ....
gi 30689902 121 DTYR 124
Cdd:COG2956 144 AHAY 147
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 7-120 9.03e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 36.25  E-value: 9.03e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30689902   7 DFERLIMFEHARKNSEAQYKNDPLDSENLLKWGGALLELSQFQpipeaklmlnDAISKLEEALTINPGKHQALWCIANAY 86
Cdd:COG2956  85 DYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWE----------KAIEVLERLLKLGPENAHAYCELAELY 154

                        90       100       110
                ....*....|....*....|....*....|....
gi 30689902  87 tahafyvhdpeEAKEHFDKATEYFQRAENEDPGN 120
Cdd:COG2956 155 -----------LEQGDYDEAIEALEKALKLDPDC 177
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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