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Conserved domains on  [gi|15218463|ref|NP_174661|]
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methyl esterase 14 [Arabidopsis thaliana]

Protein Classification

alpha/beta hydrolase family protein( domain architecture ID 229394)

alpha/beta hydrolase family protein may catalyze the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Abhydrolase super family cl21494
alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, ...
 98-345 6.38e-68

alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, peroxidases, esterases, epoxide hydrolases and dehalogenases. The catalytic apparatus typically involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine, and often the mechanism involves a nucleophilic attack on a carbonyl carbon atom.


The actual alignment was detected with superfamily member PLN02965:

Pssm-ID: 473884 [Multi-domain]  Cd Length: 255  Bit Score: 214.01  E-value: 6.38e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463   98 FVLVHGEGFGAWCWYKMVASLEESGLSPVTVDLTGCGFNMTDTNTVSTLEEYSKPLIDLLENLPEEEKVILVGHSTGGAS 177
Cdd:PLN02965   6 FVFVHGASHGAWCWYKLATLLDAAGFKSTCVDLTGAGISLTDSNTVSSSDQYNRPLFALLSDLPPDHKVILVGHSIGGGS 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463  178 ISYALERFPEKISKAIFVCATMVSDGQRPfdvfSEELGSAERFMKESQFLIYGNGKDKPPTGFMFEKPHMKGLYFNQSPN 257
Cdd:PLN02965  86 VTEALCKFTDKISMAIYVAAAMVKPGSII----SPRLKNVMEGTEKIWDYTFGEGPDKPPTGIMMKPEFVRHYYYNQSPL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463  258 KDIALAMISMRPVPLGPMMEKVSLT-AERYGKGRRFYVQTLDDRALSPDVQEKLVRENSPEGVFKIKGSDHCPFFSKPQS 336
Cdd:PLN02965 162 EDYTLSSKLLRPAPVRAFQDLDKLPpNPEAEKVPRVYIKTAKDNLFDPVRQDVMVENWPPAQTYVLEDSDHSAFFSVPTT 241


                 ....*....
gi 15218463  337 LHKILLEIA 345
Cdd:PLN02965 242 LFQYLLQAV 250
 
Name Accession Description Interval E-value
PLN02965 PLN02965
Probable pheophorbidase
 98-345 6.38e-68

Probable pheophorbidase


Pssm-ID: 178549 [Multi-domain]  Cd Length: 255  Bit Score: 214.01  E-value: 6.38e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463   98 FVLVHGEGFGAWCWYKMVASLEESGLSPVTVDLTGCGFNMTDTNTVSTLEEYSKPLIDLLENLPEEEKVILVGHSTGGAS 177
Cdd:PLN02965   6 FVFVHGASHGAWCWYKLATLLDAAGFKSTCVDLTGAGISLTDSNTVSSSDQYNRPLFALLSDLPPDHKVILVGHSIGGGS 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463  178 ISYALERFPEKISKAIFVCATMVSDGQRPfdvfSEELGSAERFMKESQFLIYGNGKDKPPTGFMFEKPHMKGLYFNQSPN 257
Cdd:PLN02965  86 VTEALCKFTDKISMAIYVAAAMVKPGSII----SPRLKNVMEGTEKIWDYTFGEGPDKPPTGIMMKPEFVRHYYYNQSPL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463  258 KDIALAMISMRPVPLGPMMEKVSLT-AERYGKGRRFYVQTLDDRALSPDVQEKLVRENSPEGVFKIKGSDHCPFFSKPQS 336
Cdd:PLN02965 162 EDYTLSSKLLRPAPVRAFQDLDKLPpNPEAEKVPRVYIKTAKDNLFDPVRQDVMVENWPPAQTYVLEDSDHSAFFSVPTT 241


                 ....*....
gi 15218463  337 LHKILLEIA 345
Cdd:PLN02965 242 LFQYLLQAV 250
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 98-332 2.39e-16

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 76.74  E-value: 2.39e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463    98 FVLVHGegfgAWCWYKMVASLEESGLSPVTVDLTGCGFNMTDTNTVSTLEEYskplIDLLENLPEEEKVILVGHSTGGAs 177
Cdd:pfam12697   1 VVLVHG----AGLSAAPLAALLAAGVAVLAPDLPGHGSSSPPPLDLADLADL----AALLDELGAARPVVLVGHSLGGA- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463   178 isYALERFPEKISKAIFVCATMVSDGQRPFDvfseelgsaerfmkesqFLIYGNGKDKPPTGFMFEKPHMKGLYFNQSPN 257
Cdd:pfam12697  72 --VALAAAAAALVVGVLVAPLAAPPGLLAAL-----------------LALLARLGAALAAPAWLAAESLARGFLDDLPA 132

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15218463   258 KDIALAMISmRPVPLGPMMEKVSLTAERyGKGRRFYVQTLDDRALSPDVQEkLVRENSPEGVFKIKGSDHCPFFS 332
Cdd:pfam12697 133 DAEWAAALA-RLAALLAALALLPLAAWR-DLPVPVLVLAEEDRLVPELAQR-LLAALAGARLVVLPGAGHLPLDD 204
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 99-199 1.51e-13

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 68.87  E-value: 1.51e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463  99 VLVHGEGFGAWCWYKMVASLEEsGLSPVTVDLTGCGFNmTDTNTVSTLEEYSKPLIDLLENLpEEEKVILVGHSTGGASI 178
Cdd:COG0596  27 VLLHGLPGSSYEWRPLIPALAA-GYRVIAPDLRGHGRS-DKPAGGYTLDDLADDLAALLDAL-GLERVVLVGHSMGGMVA 103

                        90       100
                ....*....|....*....|.
gi 15218463 179 SYALERFPEKISKAIFVCATM 199
Cdd:COG0596 104 LELAARHPERVAGLVLVDEVL 124
 
Name Accession Description Interval E-value
PLN02965 PLN02965
Probable pheophorbidase
 98-345 6.38e-68

Probable pheophorbidase


Pssm-ID: 178549 [Multi-domain]  Cd Length: 255  Bit Score: 214.01  E-value: 6.38e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463   98 FVLVHGEGFGAWCWYKMVASLEESGLSPVTVDLTGCGFNMTDTNTVSTLEEYSKPLIDLLENLPEEEKVILVGHSTGGAS 177
Cdd:PLN02965   6 FVFVHGASHGAWCWYKLATLLDAAGFKSTCVDLTGAGISLTDSNTVSSSDQYNRPLFALLSDLPPDHKVILVGHSIGGGS 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463  178 ISYALERFPEKISKAIFVCATMVSDGQRPfdvfSEELGSAERFMKESQFLIYGNGKDKPPTGFMFEKPHMKGLYFNQSPN 257
Cdd:PLN02965  86 VTEALCKFTDKISMAIYVAAAMVKPGSII----SPRLKNVMEGTEKIWDYTFGEGPDKPPTGIMMKPEFVRHYYYNQSPL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463  258 KDIALAMISMRPVPLGPMMEKVSLT-AERYGKGRRFYVQTLDDRALSPDVQEKLVRENSPEGVFKIKGSDHCPFFSKPQS 336
Cdd:PLN02965 162 EDYTLSSKLLRPAPVRAFQDLDKLPpNPEAEKVPRVYIKTAKDNLFDPVRQDVMVENWPPAQTYVLEDSDHSAFFSVPTT 241


                 ....*....
gi 15218463  337 LHKILLEIA 345
Cdd:PLN02965 242 LFQYLLQAV 250
PLN02211 PLN02211
methyl indole-3-acetate methyltransferase
 82-345 1.71e-60

methyl indole-3-acetate methyltransferase


Pssm-ID: 215128  Cd Length: 273  Bit Score: 195.49  E-value: 1.71e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463   82 NGKQVPDFSESLIVKKFVLVHGEGFGAWCWYKMVASLEESGLSPVTVDLTGCGFNMTDTNTVSTLEEYSKPLIDLLENLP 161
Cdd:PLN02211   5 NGEEVTDMKPNRQPPHFVLIHGISGGSWCWYKIRCLMENSGYKVTCIDLKSAGIDQSDADSVTTFDEYNKPLIDFLSSLP 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463  162 EEEKVILVGHSTGGASISYALERFPEKISKAIFVCATMVSDGQRPFDVFSEELGSAERFmKESQFLIYGNGKDKPPTGFM 241
Cdd:PLN02211  85 ENEKVILVGHSAGGLSVTQAIHRFPKKICLAVYVAATMLKLGFQTDEDMKDGVPDLSEF-GDVYELGFGLGPDQPPTSAI 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463  242 FEKPHMKGLYFNQSPNKDIALAMISMRPVPLgpmmekVSLTAERYGKGR-------RFYVQTLDDRALSPDVQEKLVREN 314
Cdd:PLN02211 164 IKKEFRRKILYQMSPQEDSTLAAMLLRPGPI------LALRSARFEEETgdidkvpRVYIKTLHDHVVKPEQQEAMIKRW 237

                        250       260       270
                 ....*....|....*....|....*....|.
gi 15218463  315 SPEGVFKIKgSDHCPFFSKPQSLHKILLEIA 345
Cdd:PLN02211 238 PPSQVYELE-SDHSPFFSTPFLLFGLLIKAA 267
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 98-332 2.39e-16

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 76.74  E-value: 2.39e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463    98 FVLVHGegfgAWCWYKMVASLEESGLSPVTVDLTGCGFNMTDTNTVSTLEEYskplIDLLENLPEEEKVILVGHSTGGAs 177
Cdd:pfam12697   1 VVLVHG----AGLSAAPLAALLAAGVAVLAPDLPGHGSSSPPPLDLADLADL----AALLDELGAARPVVLVGHSLGGA- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463   178 isYALERFPEKISKAIFVCATMVSDGQRPFDvfseelgsaerfmkesqFLIYGNGKDKPPTGFMFEKPHMKGLYFNQSPN 257
Cdd:pfam12697  72 --VALAAAAAALVVGVLVAPLAAPPGLLAAL-----------------LALLARLGAALAAPAWLAAESLARGFLDDLPA 132

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15218463   258 KDIALAMISmRPVPLGPMMEKVSLTAERyGKGRRFYVQTLDDRALSPDVQEkLVRENSPEGVFKIKGSDHCPFFS 332
Cdd:pfam12697 133 DAEWAAALA-RLAALLAALALLPLAAWR-DLPVPVLVLAEEDRLVPELAQR-LLAALAGARLVVLPGAGHLPLDD 204
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 99-199 1.51e-13

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 68.87  E-value: 1.51e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463  99 VLVHGEGFGAWCWYKMVASLEEsGLSPVTVDLTGCGFNmTDTNTVSTLEEYSKPLIDLLENLpEEEKVILVGHSTGGASI 178
Cdd:COG0596  27 VLLHGLPGSSYEWRPLIPALAA-GYRVIAPDLRGHGRS-DKPAGGYTLDDLADDLAALLDAL-GLERVVLVGHSMGGMVA 103

                        90       100
                ....*....|....*....|.
gi 15218463 179 SYALERFPEKISKAIFVCATM 199
Cdd:COG0596 104 LELAARHPERVAGLVLVDEVL 124
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 98-334 1.94e-12

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 66.37  E-value: 1.94e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463    98 FVLVHGEGFGAWCWYKMVASLEESGLSPVTVDLTGCGFNMTDTNTVS-TLEEYSKPLIDLLENLPEEeKVILVGHSTGGA 176
Cdd:pfam00561   3 VLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKAQDDyRTDDLAEDLEYILEALGLE-KVNLVGHSMGGL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463   177 SISYALERFPEKISKAIFVCATMVSD---------GQRPFDVFSEELGSAERFMKESQFLIYgNGKDKPPTGFMFEKPHM 247
Cdd:pfam00561  82 IALAYAAKYPDRVKALVLLGALDPPHeldeadrfiLALFPGFFDGFVADFAPNPLGRLVAKL-LALLLLRLRLLKALPLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463   248 KGLYFNQSPNKDIALAMISmrpvplGPMMEKVSLTAERYGKGRR----FYVQTLDDRALSPDVQEKLVRENSPEGVFKIK 323
Cdd:pfam00561 161 NKRFPSGDYALAKSLVTGA------LLFIETWSTELRAKFLGRLdeptLIIWGDQDPLVPPQALEKLAQLFPNARLVVIP 234

                         250
                  ....*....|.
gi 15218463   324 GSDHCPFFSKP 334
Cdd:pfam00561 235 DAGHFAFLEGP 245
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
99-202 1.92e-10

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 60.02  E-value: 1.92e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463  99 VLVHGEGFGAWCWYKMVASLEESGLSPVTVDLTGCGFNMTDTNTVSTLEEYS---KPLIDLLENLPEEeKVILVGHSTGG 175
Cdd:COG2267  32 VLVHGLGEHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSFDDYVddlRAALDALRARPGL-PVVLLGHSMGG 110

                        90       100
                ....*....|....*....|....*..
gi 15218463 176 ASISYALERFPEKISKAIFVCATMVSD 202
Cdd:COG2267 111 LIALLYAARYPDRVAGLVLLAPAYRAD 137
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 99-195 2.84e-10

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 56.76  E-value: 2.84e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463  99 VLVHGEGFGAWCWYKMVASLEESGLSPVTVDLTGcgfnmtdtnTVSTLEEYSKPLIDLLENLPEE---EKVILVGHSTGG 175
Cdd:COG1075   9 VLVHGLGGSAASWAPLAPRLRAAGYPVYALNYPS---------TNGSIEDSAEQLAAFVDAVLAAtgaEKVDLVGHSMGG 79

                        90       100
                ....*....|....*....|..
gi 15218463 176 ASISYALERF--PEKISKAIFV 195
Cdd:COG1075  80 LVARYYLKRLggAAKVARVVTL 101
DUF1749 pfam08538
Protein of unknown function (DUF1749); This is a plant and fungal family of unknown function. ...
 112-212 8.87e-05

Protein of unknown function (DUF1749); This is a plant and fungal family of unknown function. This family contains many hypothetical proteins.


Pssm-ID: 369936  Cd Length: 299  Bit Score: 43.57  E-value: 8.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463   112 YKMVASLEESGLSPVTVDLT------GCGFNMTDTNTVSTLEEYskpLIDLLENLPEEEKVILVGHSTGGASISYAL--- 182
Cdd:pfam08538  50 QPLANALDESGWSVVQPQTSssyggwGTGSLKRDDEEISALVEY---LKTTKSGTFGMRKVVLMGHSTGSQDVMYYLtss 126

                          90       100       110
                  ....*....|....*....|....*....|.
gi 15218463   183 -ERFPEKISKAIFVCAtmVSDGQRPFDVFSE 212
Cdd:pfam08538 127 nEMGRPKVDGGILQAP--VSDREAILTVIEE 155
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
98-205 1.63e-04

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 42.62  E-value: 1.63e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463  98 FVLVHGegFGAwCWYKM--VAS-LEESGLSPVTVDLTGCGFNMTDTNTVsTLEEYSKPLIDLLENLPEE-EKVILVGHST 173
Cdd:COG1647  18 VLLLHG--FTG-SPAEMrpLAEaLAKAGYTVYAPRLPGHGTSPEDLLKT-TWEDWLEDVEEAYEILKAGyDKVIVIGLSM 93

                        90       100       110
                ....*....|....*....|....*....|..
gi 15218463 174 GGASISYALERFPEkISKAIFVCATMVSDGQR 205
Cdd:COG1647  94 GGLLALLLAARYPD-VAGLVLLSPALKIDDPS 124
PLN02894 PLN02894
hydrolase, alpha/beta fold family protein
 99-222 4.97e-04

hydrolase, alpha/beta fold family protein


Pssm-ID: 215484 [Multi-domain]  Cd Length: 402  Bit Score: 41.82  E-value: 4.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463   99 VLVHGEGFGAWCWYKMVASLEeSGLSPVTVDLTGCGFNMTDTNTVSTLEEYSKPLIDLLE------NLpeeEKVILVGHS 172
Cdd:PLN02894 109 VMVHGYGASQGFFFRNFDALA-SRFRVIAIDQLGWGGSSRPDFTCKSTEETEAWFIDSFEewrkakNL---SNFILLGHS 184

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 15218463  173 TGG-ASISYALeRFPEKISKAIFVCATMVSdgqrpfdvfSEELGSAERFMK 222
Cdd:PLN02894 185 FGGyVAAKYAL-KHPEHVQHLILVGPAGFS---------SESDDKSEWLTK 225
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
99-202 1.16e-03

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 40.00  E-value: 1.16e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218463  99 VLVHGEGFGAWCWYKMVAS-LEESGLSPVTVDLTGCGFNMTDTNTVstLEEYSKPLIDLLENLPE--EEKVILVGHSTGG 175
Cdd:COG1506  27 VYVHGGPGSRDDSFLPLAQaLASRGYAVLAPDYRGYGESAGDWGGD--EVDDVLAAIDYLAARPYvdPDRIGIYGHSYGG 104

                        90       100
                ....*....|....*....|....*..
gi 15218463 176 ASISYALERFPEKISKAIFVCAtmVSD 202
Cdd:COG1506 105 YMALLAAARHPDRFKAAVALAG--VSD 129
YdeN COG3545
Predicted esterase of the alpha/beta hydrolase fold [General function prediction only];
163-209 4.97e-03

Predicted esterase of the alpha/beta hydrolase fold [General function prediction only];


Pssm-ID: 442766 [Multi-domain]  Cd Length: 170  Bit Score: 37.52  E-value: 4.97e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*..
gi 15218463 163 EEKVILVGHSTGGASISYALERFPEKISKAIFVCatmvsdgqrPFDV 209
Cdd:COG3545  53 DGPVVLVAHSLGCLAVAHWAARLPRKVAGALLVA---------PPDP 90
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 153-200 8.01e-03

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 37.19  E-value: 8.01e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 15218463   153 LIDLLENLPEEEKVILVGHSTGGA-SISYALERfPEKISKAIFvCATMV 200
Cdd:pfam12146  65 FVDKIREEHPGLPLFLLGHSMGGLiAALYALRY-PDKVDGLIL-SAPAL 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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