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Conserved domains on  [gi|15217799|ref|NP_176098|]
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purine permease 17 [Arabidopsis thaliana]

Protein Classification

purine permease( domain architecture ID 12180965)

purine permease is a proton-coupled transporter that mediates the uptake of nucleosides, nucleotides, and their derivatives, such as adenine and cytosine, as well as purine derivatives (hypoxanthine), phytohormones (zeatin and kinetin), and alkaloids (caffeine and nicotine)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PUNUT pfam16913
Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal ...
 43-384 2.48e-123

Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal purine transporters. Most members are 10-pass transmembrane proteins, and they belong to the drug/metabolite transporter (dmt) superfamily. The plant vascular system transports nucloebases and their derivatives such as cytokinins and caffeine by a common H+-coupled high-affinity purine transport system; the PUNUT family members carry out this transport.


:

Pssm-ID: 293518 [Multi-domain]  Cd Length: 321  Bit Score: 359.29  E-value: 2.48e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217799    43 ISVSLCLFLVLLGDSLVMLLLNFFYVQMKqdrreeydqdlqyKGTWTQALIQNAAFPIL-IPLFFIFPKPKQHLETNNTS 121
Cdd:pfam16913   1 ILVIISIFFLLIGQAISTLLGRLYFVNGG-------------KSTWLQTLVQTAGFPLLlLPLLFSFLSKKRNQETTSFS 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217799   122 FLSLRLFFLYLSLGVLVAAHSKLFALGKLVSNYGIFSLISTTQLIFTAVLTAIINRFKFTRWIIISI-LLTIVIYVLGTP 200
Cdd:pfam16913  68 SSFKRLVIIYIVLGLLVGADNFLYSYGLLYLPVSTFSLILATQLAFTAIFSYFINKQKFTPFIINSVvLLTISAALLALD 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217799   201 DFGGQPHDGEEFGYNIQAWLAFSATIAFSLSLCLIQLGFEKlqvktkrYGNEKVFRMVLEMQICVAFVASVVCLVGLFAS 280
Cdd:pfam16913 148 SSSDKPSGESKKKYVIGFWCTIGASALFSLILCLVELAFEK-------VLKRRTFSMVLEMQIVMSLVATCVCVIGLFAS 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217799   281 DEYKELKGDSKRFKKGETYYVLSLVGLALSWQVWAVGMIGLVHYVSGLFGDVVHMCASPFVALFVVLAFdfmDDVFSWPR 360
Cdd:pfam16913 221 GEFKDLKGEMEEFKKGKSLYVLTLVGTAVSWQVYFVGAVGLVFLVSSLFSNVISTVLLPVVPVLAVIAF---HDKFSGFK 297

                         330       340
                  ....*....|....*....|....
gi 15217799   361 IGALIGTVLALGSYFYTLHKRNKK 384
Cdd:pfam16913 298 GVALVLAIWGFASYFYGLYKDKKK 321
 
Name Accession Description Interval E-value
PUNUT pfam16913
Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal ...
 43-384 2.48e-123

Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal purine transporters. Most members are 10-pass transmembrane proteins, and they belong to the drug/metabolite transporter (dmt) superfamily. The plant vascular system transports nucloebases and their derivatives such as cytokinins and caffeine by a common H+-coupled high-affinity purine transport system; the PUNUT family members carry out this transport.


Pssm-ID: 293518 [Multi-domain]  Cd Length: 321  Bit Score: 359.29  E-value: 2.48e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217799    43 ISVSLCLFLVLLGDSLVMLLLNFFYVQMKqdrreeydqdlqyKGTWTQALIQNAAFPIL-IPLFFIFPKPKQHLETNNTS 121
Cdd:pfam16913   1 ILVIISIFFLLIGQAISTLLGRLYFVNGG-------------KSTWLQTLVQTAGFPLLlLPLLFSFLSKKRNQETTSFS 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217799   122 FLSLRLFFLYLSLGVLVAAHSKLFALGKLVSNYGIFSLISTTQLIFTAVLTAIINRFKFTRWIIISI-LLTIVIYVLGTP 200
Cdd:pfam16913  68 SSFKRLVIIYIVLGLLVGADNFLYSYGLLYLPVSTFSLILATQLAFTAIFSYFINKQKFTPFIINSVvLLTISAALLALD 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217799   201 DFGGQPHDGEEFGYNIQAWLAFSATIAFSLSLCLIQLGFEKlqvktkrYGNEKVFRMVLEMQICVAFVASVVCLVGLFAS 280
Cdd:pfam16913 148 SSSDKPSGESKKKYVIGFWCTIGASALFSLILCLVELAFEK-------VLKRRTFSMVLEMQIVMSLVATCVCVIGLFAS 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217799   281 DEYKELKGDSKRFKKGETYYVLSLVGLALSWQVWAVGMIGLVHYVSGLFGDVVHMCASPFVALFVVLAFdfmDDVFSWPR 360
Cdd:pfam16913 221 GEFKDLKGEMEEFKKGKSLYVLTLVGTAVSWQVYFVGAVGLVFLVSSLFSNVISTVLLPVVPVLAVIAF---HDKFSGFK 297

                         330       340
                  ....*....|....*....|....
gi 15217799   361 IGALIGTVLALGSYFYTLHKRNKK 384
Cdd:pfam16913 298 GVALVLAIWGFASYFYGLYKDKKK 321
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 97-235 3.05e-03

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 39.05  E-value: 3.05e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217799  97 AFPILIPLFFIFPKPKQHLetnntsflSLRLFFLYLSLGVL-VAAHSKLFALGKLVSNYGIFSLISTTQLIFTAVLTAII 175
Cdd:COG0697  42 AALLLLPLLLLRGRRLPPL--------SRRDWLLLLLRGLLgLALAFLLFFLALQYTPAALAALLLALAPLFVALLAALL 113

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15217799 176 NRFKFTRWIIISILLTIV-IYVLGTPDFGGQphdgeeFGYNIQAWLAFSATIAFSLSLCLI 235
Cdd:COG0697 114 LGERLSRRRWLGLLLGFAgVLLIVGPGGGGG------GGSLLGDLLALLAALSWALYTVLT 168
 
Name Accession Description Interval E-value
PUNUT pfam16913
Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal ...
 43-384 2.48e-123

Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal purine transporters. Most members are 10-pass transmembrane proteins, and they belong to the drug/metabolite transporter (dmt) superfamily. The plant vascular system transports nucloebases and their derivatives such as cytokinins and caffeine by a common H+-coupled high-affinity purine transport system; the PUNUT family members carry out this transport.


Pssm-ID: 293518 [Multi-domain]  Cd Length: 321  Bit Score: 359.29  E-value: 2.48e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217799    43 ISVSLCLFLVLLGDSLVMLLLNFFYVQMKqdrreeydqdlqyKGTWTQALIQNAAFPIL-IPLFFIFPKPKQHLETNNTS 121
Cdd:pfam16913   1 ILVIISIFFLLIGQAISTLLGRLYFVNGG-------------KSTWLQTLVQTAGFPLLlLPLLFSFLSKKRNQETTSFS 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217799   122 FLSLRLFFLYLSLGVLVAAHSKLFALGKLVSNYGIFSLISTTQLIFTAVLTAIINRFKFTRWIIISI-LLTIVIYVLGTP 200
Cdd:pfam16913  68 SSFKRLVIIYIVLGLLVGADNFLYSYGLLYLPVSTFSLILATQLAFTAIFSYFINKQKFTPFIINSVvLLTISAALLALD 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217799   201 DFGGQPHDGEEFGYNIQAWLAFSATIAFSLSLCLIQLGFEKlqvktkrYGNEKVFRMVLEMQICVAFVASVVCLVGLFAS 280
Cdd:pfam16913 148 SSSDKPSGESKKKYVIGFWCTIGASALFSLILCLVELAFEK-------VLKRRTFSMVLEMQIVMSLVATCVCVIGLFAS 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217799   281 DEYKELKGDSKRFKKGETYYVLSLVGLALSWQVWAVGMIGLVHYVSGLFGDVVHMCASPFVALFVVLAFdfmDDVFSWPR 360
Cdd:pfam16913 221 GEFKDLKGEMEEFKKGKSLYVLTLVGTAVSWQVYFVGAVGLVFLVSSLFSNVISTVLLPVVPVLAVIAF---HDKFSGFK 297

                         330       340
                  ....*....|....*....|....
gi 15217799   361 IGALIGTVLALGSYFYTLHKRNKK 384
Cdd:pfam16913 298 GVALVLAIWGFASYFYGLYKDKKK 321
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 97-235 3.05e-03

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 39.05  E-value: 3.05e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217799  97 AFPILIPLFFIFPKPKQHLetnntsflSLRLFFLYLSLGVL-VAAHSKLFALGKLVSNYGIFSLISTTQLIFTAVLTAII 175
Cdd:COG0697  42 AALLLLPLLLLRGRRLPPL--------SRRDWLLLLLRGLLgLALAFLLFFLALQYTPAALAALLLALAPLFVALLAALL 113

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15217799 176 NRFKFTRWIIISILLTIV-IYVLGTPDFGGQphdgeeFGYNIQAWLAFSATIAFSLSLCLI 235
Cdd:COG0697 114 LGERLSRRRWLGLLLGFAgVLLIVGPGGGGG------GGSLLGDLLALLAALSWALYTVLT 168
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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