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Conserved domains on  [gi|42562928|ref|NP_176608|]
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MuDR family transposase [Arabidopsis thaliana]

Protein Classification

MULE family transposase( domain architecture ID 19335375)

MULE (Mutator-like element) family transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0006313|GO:0003677|GO:0004803|GO:0046872|GO:0032196|GO:0015074|GO:0006310|GO:0008270
PubMed:  30988700|19018586|17130173|22474413|20615441|11774877|20215432|20885819|17165262|12151216

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DBD_Tnp_Mut super family cl07846
MuDR family transposase; This region is found in plant proteins that are presumed to be the ...
 185-248 2.10e-15

MuDR family transposase; This region is found in plant proteins that are presumed to be the transposases for Mutator transposable elements. These transposons contain two ORFs. The molecular function of this region is unknown.


The actual alignment was detected with superfamily member pfam03108:

Pssm-ID: 427142  Cd Length: 67  Bit Score: 71.34  E-value: 2.10e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 42562928   185 MHLGLCFKDRDELKKAVDWWCIRRRRNCIVRETEKEMYTFECVRWKCKWSLRAARMEEHGLVEI 248
Cdd:pfam03108   4 MRVGQCFPDLAEFRKALRKYAIARQFKFRLRKSDKDRFTVECEGEGCPWRIHASRRPETGLFEI 67
ZnF_PMZ smart00575
plant mutator transposase zinc finger;
642-668 7.98e-09

plant mutator transposase zinc finger;


:

Pssm-ID: 128845  Cd Length: 28  Bit Score: 51.40  E-value: 7.98e-09
                           10        20
                   ....*....|....*....|....*..
gi 42562928    642 TCTCRKFQSYKFPCLHALAVFEKLKIN 668
Cdd:smart00575   2 TCSCRKFQLSGIPCRHALAAAIHIGLS 28
MULE super family cl48097
MULE transposase domain; This domain was identified by Babu and colleagues.
 378-474 2.77e-07

MULE transposase domain; This domain was identified by Babu and colleagues.


The actual alignment was detected with superfamily member pfam10551:

Pssm-ID: 463145 [Multi-domain]  Cd Length: 98  Bit Score: 49.18  E-value: 2.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42562928   378 LIVVDTKSLNGKYQLKLMIASGVDAANKFFPLAFAVTKEVSTDSWRWFFTKI---REKVTQRKDLCLISSPLRDIVAVVN 454
Cdd:pfam10551   1 VLLIDGTYKTNKYKMPLFTAVGVDHHGQSFPIAFGLVSNETEESFTWLFDQLiafRECMSGLSPQVIITDRDKALKNAIN 80

                          90       100
                  ....*....|....*....|
gi 42562928   455 EPGslwqePWAHHKFCLNHL 474
Cdd:pfam10551  81 LVF-----PEAQHRLCIFHI 95
 
Name Accession Description Interval E-value
DBD_Tnp_Mut pfam03108
MuDR family transposase; This region is found in plant proteins that are presumed to be the ...
 185-248 2.10e-15

MuDR family transposase; This region is found in plant proteins that are presumed to be the transposases for Mutator transposable elements. These transposons contain two ORFs. The molecular function of this region is unknown.


Pssm-ID: 427142  Cd Length: 67  Bit Score: 71.34  E-value: 2.10e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 42562928   185 MHLGLCFKDRDELKKAVDWWCIRRRRNCIVRETEKEMYTFECVRWKCKWSLRAARMEEHGLVEI 248
Cdd:pfam03108   4 MRVGQCFPDLAEFRKALRKYAIARQFKFRLRKSDKDRFTVECEGEGCPWRIHASRRPETGLFEI 67
ZnF_PMZ smart00575
plant mutator transposase zinc finger;
642-668 7.98e-09

plant mutator transposase zinc finger;


Pssm-ID: 128845  Cd Length: 28  Bit Score: 51.40  E-value: 7.98e-09
                           10        20
                   ....*....|....*....|....*..
gi 42562928    642 TCTCRKFQSYKFPCLHALAVFEKLKIN 668
Cdd:smart00575   2 TCSCRKFQLSGIPCRHALAAAIHIGLS 28
MULE pfam10551
MULE transposase domain; This domain was identified by Babu and colleagues.
 378-474 2.77e-07

MULE transposase domain; This domain was identified by Babu and colleagues.


Pssm-ID: 463145 [Multi-domain]  Cd Length: 98  Bit Score: 49.18  E-value: 2.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42562928   378 LIVVDTKSLNGKYQLKLMIASGVDAANKFFPLAFAVTKEVSTDSWRWFFTKI---REKVTQRKDLCLISSPLRDIVAVVN 454
Cdd:pfam10551   1 VLLIDGTYKTNKYKMPLFTAVGVDHHGQSFPIAFGLVSNETEESFTWLFDQLiafRECMSGLSPQVIITDRDKALKNAIN 80

                          90       100
                  ....*....|....*....|
gi 42562928   455 EPGslwqePWAHHKFCLNHL 474
Cdd:pfam10551  81 LVF-----PEAQHRLCIFHI 95
SWIM pfam04434
SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is ...
 634-666 4.35e-07

SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is predicted to be organized into two N-terminal beta-strands and a C-terminal alpha helix, thus possibly adopting a fold similar to that of the C2H2 zinc finger (pfam00096). SWIM is thought to be a versatile domain that can interact with DNA or proteins in different contexts.


Pssm-ID: 309540  Cd Length: 38  Bit Score: 46.64  E-value: 4.35e-07
                          10        20        30
                  ....*....|....*....|....*....|...
gi 42562928   634 WIVQLNVSTCTCRKFQSYKFPCLHALAVFEKLK 666
Cdd:pfam04434   6 DLDGLEKASCSCPDFQLNGIPCKHALAVLLALG 38
 
Name Accession Description Interval E-value
DBD_Tnp_Mut pfam03108
MuDR family transposase; This region is found in plant proteins that are presumed to be the ...
 185-248 2.10e-15

MuDR family transposase; This region is found in plant proteins that are presumed to be the transposases for Mutator transposable elements. These transposons contain two ORFs. The molecular function of this region is unknown.


Pssm-ID: 427142  Cd Length: 67  Bit Score: 71.34  E-value: 2.10e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 42562928   185 MHLGLCFKDRDELKKAVDWWCIRRRRNCIVRETEKEMYTFECVRWKCKWSLRAARMEEHGLVEI 248
Cdd:pfam03108   4 MRVGQCFPDLAEFRKALRKYAIARQFKFRLRKSDKDRFTVECEGEGCPWRIHASRRPETGLFEI 67
ZnF_PMZ smart00575
plant mutator transposase zinc finger;
642-668 7.98e-09

plant mutator transposase zinc finger;


Pssm-ID: 128845  Cd Length: 28  Bit Score: 51.40  E-value: 7.98e-09
                           10        20
                   ....*....|....*....|....*..
gi 42562928    642 TCTCRKFQSYKFPCLHALAVFEKLKIN 668
Cdd:smart00575   2 TCSCRKFQLSGIPCRHALAAAIHIGLS 28
MULE pfam10551
MULE transposase domain; This domain was identified by Babu and colleagues.
 378-474 2.77e-07

MULE transposase domain; This domain was identified by Babu and colleagues.


Pssm-ID: 463145 [Multi-domain]  Cd Length: 98  Bit Score: 49.18  E-value: 2.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42562928   378 LIVVDTKSLNGKYQLKLMIASGVDAANKFFPLAFAVTKEVSTDSWRWFFTKI---REKVTQRKDLCLISSPLRDIVAVVN 454
Cdd:pfam10551   1 VLLIDGTYKTNKYKMPLFTAVGVDHHGQSFPIAFGLVSNETEESFTWLFDQLiafRECMSGLSPQVIITDRDKALKNAIN 80

                          90       100
                  ....*....|....*....|
gi 42562928   455 EPGslwqePWAHHKFCLNHL 474
Cdd:pfam10551  81 LVF-----PEAQHRLCIFHI 95
SWIM pfam04434
SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is ...
 634-666 4.35e-07

SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is predicted to be organized into two N-terminal beta-strands and a C-terminal alpha helix, thus possibly adopting a fold similar to that of the C2H2 zinc finger (pfam00096). SWIM is thought to be a versatile domain that can interact with DNA or proteins in different contexts.


Pssm-ID: 309540  Cd Length: 38  Bit Score: 46.64  E-value: 4.35e-07
                          10        20        30
                  ....*....|....*....|....*....|...
gi 42562928   634 WIVQLNVSTCTCRKFQSYKFPCLHALAVFEKLK 666
Cdd:pfam04434   6 DLDGLEKASCSCPDFQLNGIPCKHALAVLLALG 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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