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Conserved domains on  [gi|15222161|ref|NP_177661|]
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RAD-like 6 [Arabidopsis thaliana]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 10073748)

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein binds DNA and may function as a transcription factor

CATH:  1.20.58.1880
Gene Ontology:  GO:0006355|GO:0003677|GO:0003700
PubMed:  8882580|15040448|16877755
SCOP:  4000317

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 11-54 1.43e-06

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


:

Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 42.18  E-value: 1.43e-06
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 15222161  11 PWTFSQNKMFERALAVYDKDtpdRWHNVAKAVGGKTVEEVKRHY 54
Cdd:cd00167   1 PWTEEEDELLLEAVKKYGKN---NWEKIAKELPGRTPKQCRERW 41
 
Name Accession Description Interval E-value
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 11-54 1.43e-06

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 42.18  E-value: 1.43e-06
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 15222161  11 PWTFSQNKMFERALAVYDKDtpdRWHNVAKAVGGKTVEEVKRHY 54
Cdd:cd00167   1 PWTEEEDELLLEAVKKYGKN---NWEKIAKELPGRTPKQCRERW 41
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
11-54 6.13e-06

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 40.67  E-value: 6.13e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 15222161     11 PWTFSQNKMFERALAVYDKDtpdRWHNVAKAVGGKTVEEVKRHY 54
Cdd:smart00717   3 EWTEEEDELLIELVKKYGKN---NWEKIAKELPGRTAEQCRERW 43
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 11-54 2.17e-04

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 36.33  E-value: 2.17e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 15222161    11 PWTFSQNKMFERALAVYdkdtPDRWHNVAKAVGGKTVEEVKRHY 54
Cdd:pfam00249   3 PWTPEEDELLLEAVEKL----GNRWKKIAKLLPGRTDNQCKNRW 42
 
Name Accession Description Interval E-value
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 11-54 1.43e-06

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 42.18  E-value: 1.43e-06
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 15222161  11 PWTFSQNKMFERALAVYDKDtpdRWHNVAKAVGGKTVEEVKRHY 54
Cdd:cd00167   1 PWTEEEDELLLEAVKKYGKN---NWEKIAKELPGRTPKQCRERW 41
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
11-54 6.13e-06

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 40.67  E-value: 6.13e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 15222161     11 PWTFSQNKMFERALAVYDKDtpdRWHNVAKAVGGKTVEEVKRHY 54
Cdd:smart00717   3 EWTEEEDELLIELVKKYGKN---NWEKIAKELPGRTAEQCRERW 43
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 11-54 2.17e-04

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 36.33  E-value: 2.17e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 15222161    11 PWTFSQNKMFERALAVYdkdtPDRWHNVAKAVGGKTVEEVKRHY 54
Cdd:pfam00249   3 PWTPEEDELLLEAVEKL----GNRWKKIAKLLPGRTDNQCKNRW 42
BphC-JF8_C_like cd09014
C-terminal, catalytic domain of BphC_JF8, (2,3-dihydroxybiphenyl 1,2-dioxygenase); 2, ...
 4-67 3.60e-03

C-terminal, catalytic domain of BphC_JF8, (2,3-dihydroxybiphenyl 1,2-dioxygenase); 2,3-dihydroxybiphenyl 1,2-dioxygenase (BphC) catalyzes the extradiol ring cleavage reaction of 2,3-dihydroxybiphenyl, a key step in the polychlorinated biphenyls (PCBs) degradation pathway (bph pathway). BphC belongs to the type I extradiol dioxygenase family, which requires a metal ion in the active site in its catalytic mechanism. Polychlorinated biphenyl degrading bacteria demonstrate a multiplicity of BphCs. This subfamily of BphC is represented by the enzyme purified from the thermophilic biphenyl and naphthalene degrader, Bacillus sp. JF8. The members in this family of BphC enzymes may use either Mn(II) or Fe(II) as cofactors. The enzyme purified from Bacillus sp. JF8 is Mn(II)-dependent, however, the enzyme from Rhodococcus jostii RHAI has Fe(II) bound to it. BphC_JF8 is thermostable and its optimum activity is at 85 degrees C. The enzymes in this family have an internal duplication. This family represents the C-terminal repeat.


Pssm-ID: 319956  Cd Length: 167  Bit Score: 35.43  E-value: 3.60e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15222161   4 NSRSSISPWTFSQNKMFERALAVYDKDTPDRWHNVAKAVGgkTVEEVKRHYDILVEDLINIETG 67
Cdd:cd09014  39 NNGGEAGAWMSVSSLVHDVAVMRDGKGEPGRLHHLAYWYG--TPEDLLRAADIFREHGIQIEAG 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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