|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
232-747 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 689.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 232 TSTSMRNLNPSDIEKMISLKGMIIRSSSIIPEIREAVFRCLVCGYFSDPIIvDRGKISEPPTCLKQECMTKNSMTLVHNR 311
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEI-QSGRETEPTVCPPRECQSPTPFSLNHER 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 312 CRFADKQIVRLQETPDEIPEGGTPHTVSLLLHDKLVDNGKPGDRIEVTGIYRAmtVRVGPAHRTVK--SVFKTYIDCLHI 389
Cdd:smart00350 80 STFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRN--VPYGFKLNTVKglPVFATYIEANHV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 390 KKASKlRMSAEDPMDVDNSLRrvDEDVEldeeklrKFQELSKQPDIYERLSRSLAPNIWELDDVKKGLLCQLFGGNALNL 469
Cdd:smart00350 158 RKLDY-KRSFEDSSFSVQSLS--DEEEE-------EIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNL 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 470 ASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVGLTAYVAKDPETGETVLESGALVLSDRGICCID 549
Cdd:smart00350 228 PDGMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCID 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 550 EFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGSRYNPRLSVIENIHLPPTLLSRFDLIYLILDKP 629
Cdd:smart00350 308 EFDKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEV 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 630 DEQTDRRLAKHIVALHFENAESAQEEA---IDITTLTTYVSYARKNIHPKLSDEAAEELTRGYVELRKAGkFAGSSKKVI 706
Cdd:smart00350 388 DEERDRELAKHVVDLHRYSHPEEDEAFeppLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKED-SQTESRSSI 466
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 42569072 707 TATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRVA 747
Cdd:smart00350 467 PITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRES 507
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
153-837 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 653.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 153 DLFREGKYMVSIRKVIE--IEGEWIDVDAFDVFDYDPDLYNKMVRYPLEVLAIFDIVLMDIVSTINRLFEKHVQVRIFNL 230
Cdd:COG1241 11 EFLRRYKYRDEILELAQeyPEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLEPYDVSLGDAHVRITNL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 231 RTSTSMRNLNPSDIEKMISLKGMIIRSSSIIPEIREAVFRCLVCGYFSDpIIVDRGKISEPPTClkQECMTKNSMTLVHN 310
Cdd:COG1241 91 PETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETY-VPQTGEKLQEPHEC--PGCGRQGPFKLLPE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 311 RCRFADKQIVRLQETPDEIPEGGTPHTVSLLLHDKLVDNGKPGDRIEVTGIYRAMTVRVGpahRTVKSVFKTYIDCLHIK 390
Cdd:COG1241 168 KSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSG---RGKSTIFDLYLEANSIE 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 391 KASKlrmsaedpmdvdnslrrVDEDVELDEEKLRKFQELSKQPDIYERLSRSLAPNIWELDDVKKGLLCQLFGGNALNLA 470
Cdd:COG1241 245 VEEK-----------------EFEEIEITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLP 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 471 SGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVGLTAYVAKDPE-TGETVLESGALVLSDRGICCID 549
Cdd:COG1241 308 DGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGGLACID 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 550 EFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGSRYNPRLSVIENIHLPPTLLSRFDLIYLILDKP 629
Cdd:COG1241 388 ELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKP 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 630 DEQTDRRLAKHIVALH---------FENAESAQEEAIDITTLTTYVSYARKNIHPKLSDEAAEELTRGYVELRKAGkfaG 700
Cdd:COG1241 468 DEERDRELARHILKVHragelleqeIEEETEEVKPEIDPDLLRKYIAYARRNVFPVLTEEAKDLIEDFYVDMRKKG---E 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 701 SSKKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRVAMQQSATDHATGTIDMDLINTGVSASERMRRDTF 780
Cdd:COG1241 545 DEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVDPETGKFDIDVIETGTSKSQRDKMKLI 624
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 42569072 781 ASSIRDIALEkmqiGGSSMRLSELLEELKKHGgninteIHLHDVRKAVATLASEGFL 837
Cdd:COG1241 625 KDIIKELEEE----SSGGAPIEDVIEEAEEEG------IDREKAEELIEKLKRKGEI 671
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
144-835 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 631.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 144 FREARENSDDLFREGKYMVSIRKVIEIEGEWIDVDAFDVFDYDPDLYNKMVRYPLEVLAIFDIVLMDIVSTINRLFEK-- 221
Cdd:NF040949 5 FKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEYAEev 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 222 -HVQVRIFNLRTSTSMRNLNPSDIEKMISLKGMIIRSSSIIPEIREAVFRCLVCGY-FSDPIIVDRG-KISEPPT-CLkq 297
Cdd:NF040949 85 aKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCeFEWPEEEEESyEIVEPPTvCP-- 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 298 ECMTKNSMTLVHNRCRFADKQIVRLQETPDEIPEGGTPHTVSLLLHDKLVDNGKPGDRIEVTGIYRamTVRVGPAHRTVK 377
Cdd:NF040949 163 VCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILR--IKPDSSLKKGSR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 378 SVFKTYIDCLHIKKASKlrmsaedpmdvdnslrrVDEDVELDEEKLRKFQELSKQPDIYERLSRSLAPNIWELDDVKKGL 457
Cdd:NF040949 241 PIFKNYIEANHIEVSQK-----------------ELEEVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAI 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 458 LCQLFGGNALNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVGLTAYVAKDPETGETVLESGA 537
Cdd:NF040949 304 ALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGA 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 538 LVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGSRYNPRLSVIENIHLPPTLLS 617
Cdd:NF040949 384 LVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILS 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 618 RFDLIYLILDKPDEQTDRRLAKHIVALHFEnaESAQEEAIDITTLTTYVSYARKNIHPKLSDEAAEELTRGYVELRKAGK 697
Cdd:NF040949 464 RFDLIFVIRDKPNEERDRRLARHILDVHSG--KEKVKPEIDPDLLKKYIAYARKYVRPKLTEEAKKLIEDFYVEMRKSSK 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 698 FAGSSKKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRVAMQQSATDHATGTIDMDLINTGVSASERMRR 777
Cdd:NF040949 542 SSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLESVGIDVETGKIDIDTIMTGKPKSKREKM 621
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*...
gi 42569072 778 DTFASSIRDIALEKMQIggssmRLSELLEELKKHGgnINTEihlhDVRKAVATLASEG 835
Cdd:NF040949 622 SKIVEIIKELEEEEECV-----KIKELIKEAEKKG--IDEE----KVEELISDLKRSG 668
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
438-747 |
0e+00 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 581.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 438 RLSRSLAPNIWELDDVKKGLLCQLFGGNALNLAS-GANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAV 516
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFTKtGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 517 GLTAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSG 596
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 597 SRYNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRLAKHIVALHFENA-ESAQEEAIDITTLTTYVSYARKNIHP 675
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTpEHIQDEVLDVEVLTDYISYAREHIHP 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 42569072 676 KLSDEAAEELTRGYVELRKAGKFAGsskKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRVA 747
Cdd:cd17755 241 KLSEEAAQELVQAYVDMRKMGSDAR---KRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
176-810 |
9.95e-174 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 525.71 E-value: 9.95e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 176 DVDAFDVFDYDPDLYNKMVRYPLEVLAIFDIVLmdiVSTINRLFEKHV------------QVRIFNLRTSTSMRNLNPSD 243
Cdd:PTZ00111 149 EVDLMHVYSFDKVLYKLLVTFPADCIAELDKVL---VKLFNELLSKHYsdlslennsffpRARLMNKPVSDCVGNLEPSM 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 244 IEKMISLKGMIIRSSSIIPEIREAVFRC-------------LVCGYFSDPIivdRGKISEPPTClkQECMTKNSMTLVHN 310
Cdd:PTZ00111 226 ADSLVQFSGTVVRQTWIVPEITMACFRCrgqkkiglndyqpCTCEHYEYVI---QGEVNEPLLC--NECNSKYTFELNHN 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 311 RCRFADKQIVRLQETPDEIPEGGTP--------------------HTVSLLLHDKLVDNGKPGDRIEVTGIYRAMTVRVG 370
Cdd:PTZ00111 301 MCVYSTKKIVKLLQSNSSLNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGILKVTPIRTS 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 371 PAHRTVKSVFKTYIDCLHIKKasklrMSAEDPMDVDNSLRRVDEDVELDEEKLRKFQELSKQPDIYERLSRSLAPNIWEL 450
Cdd:PTZ00111 381 TTRRTLKSLYTYFVNVIHVKV-----INSTNANQPEKGLKYLGNENDFSDLQVYKILELSRNPMIYRILLDSFAPSIKAR 455
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 451 DDVKKGLLCQLFGGNA----LNLASGA-----NFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVGLTAY 521
Cdd:PTZ00111 456 NNVKIGLLCQLFSGNKnssdFNKSPDAcykvdNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTAS 535
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 522 VA-KDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGSRYN 600
Cdd:PTZ00111 536 IKfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYN 615
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 601 PRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRR----LAKHIVALHFENAESA------------QEEAI------- 657
Cdd:PTZ00111 616 KNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLislsIAKDFLLPHMTGSGNDedtydrsntmhvEDESLrsekdyn 695
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 658 --DITTLTTYVSYARKNIHPKLSDEAAEELTRGYVELRKAG--------------------KFAGSSKKVITATPRQIES 715
Cdd:PTZ00111 696 knDLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNfqtsnldelehaqedddddlYYQSSGTRMIYVSSRMISS 775
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 716 LIRLSEALARMRFSEWVEKHDVDEAFRLLRVAMQQSATDHATGTIDMDLINTGVSASERMRRDTFASSIRD-IALEKMQI 794
Cdd:PTZ00111 776 IIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVDPTTGKIDFDQLHQGITTNKMQQLNQMYEQVLSvLTRSSNQD 855
|
730
....*....|....*.
gi 42569072 795 GGSSMRLSELLEELKK 810
Cdd:PTZ00111 856 SNKSLDLNEVLSLCHK 871
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
423-645 |
1.69e-137 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 406.92 E-value: 1.69e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 423 LRKFQELSKQPDIYERLSRSLAPNIWELDDVKKGLLCQLFGGNALNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLS 502
Cdd:pfam00493 2 EEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 503 PRGIYTSGRGSSAVGLTAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASL 582
Cdd:pfam00493 82 PRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATL 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 42569072 583 NARTSVLACANPSGSRYNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRLAKHIVALH 645
Cdd:pfam00493 162 NARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
140-229 |
1.46e-12 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 64.24 E-value: 1.46e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 140 FVKHFREARENsddlfrEGKYMVSIRKVIEIEGEWIDVDAFDVFDYDPDLYNKMVRYPLEVLAIFDIVLMDIVSTI---- 215
Cdd:pfam14551 7 FLEEFREDGDG------EFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKELsedp 80
|
90
....*....|....*
gi 42569072 216 -NRLFEKHVQVRIFN 229
Cdd:pfam14551 81 dYAEEEKEFQVRFYN 95
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
2-76 |
3.36e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 41.31 E-value: 3.36e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 42569072 2 ASDSSLGNTNDGPPSPGENVSSPIENTYSSPAALHRRRRGRSSTPTQFATPPPPPSRLASSNSTPPTSRPSAARS 76
Cdd:PHA03307 299 SPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSR 373
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
232-747 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 689.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 232 TSTSMRNLNPSDIEKMISLKGMIIRSSSIIPEIREAVFRCLVCGYFSDPIIvDRGKISEPPTCLKQECMTKNSMTLVHNR 311
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEI-QSGRETEPTVCPPRECQSPTPFSLNHER 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 312 CRFADKQIVRLQETPDEIPEGGTPHTVSLLLHDKLVDNGKPGDRIEVTGIYRAmtVRVGPAHRTVK--SVFKTYIDCLHI 389
Cdd:smart00350 80 STFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRN--VPYGFKLNTVKglPVFATYIEANHV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 390 KKASKlRMSAEDPMDVDNSLRrvDEDVEldeeklrKFQELSKQPDIYERLSRSLAPNIWELDDVKKGLLCQLFGGNALNL 469
Cdd:smart00350 158 RKLDY-KRSFEDSSFSVQSLS--DEEEE-------EIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNL 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 470 ASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVGLTAYVAKDPETGETVLESGALVLSDRGICCID 549
Cdd:smart00350 228 PDGMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCID 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 550 EFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGSRYNPRLSVIENIHLPPTLLSRFDLIYLILDKP 629
Cdd:smart00350 308 EFDKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEV 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 630 DEQTDRRLAKHIVALHFENAESAQEEA---IDITTLTTYVSYARKNIHPKLSDEAAEELTRGYVELRKAGkFAGSSKKVI 706
Cdd:smart00350 388 DEERDRELAKHVVDLHRYSHPEEDEAFeppLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKED-SQTESRSSI 466
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 42569072 707 TATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRVA 747
Cdd:smart00350 467 PITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRES 507
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
153-837 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 653.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 153 DLFREGKYMVSIRKVIE--IEGEWIDVDAFDVFDYDPDLYNKMVRYPLEVLAIFDIVLMDIVSTINRLFEKHVQVRIFNL 230
Cdd:COG1241 11 EFLRRYKYRDEILELAQeyPEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLEPYDVSLGDAHVRITNL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 231 RTSTSMRNLNPSDIEKMISLKGMIIRSSSIIPEIREAVFRCLVCGYFSDpIIVDRGKISEPPTClkQECMTKNSMTLVHN 310
Cdd:COG1241 91 PETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETY-VPQTGEKLQEPHEC--PGCGRQGPFKLLPE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 311 RCRFADKQIVRLQETPDEIPEGGTPHTVSLLLHDKLVDNGKPGDRIEVTGIYRAMTVRVGpahRTVKSVFKTYIDCLHIK 390
Cdd:COG1241 168 KSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSG---RGKSTIFDLYLEANSIE 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 391 KASKlrmsaedpmdvdnslrrVDEDVELDEEKLRKFQELSKQPDIYERLSRSLAPNIWELDDVKKGLLCQLFGGNALNLA 470
Cdd:COG1241 245 VEEK-----------------EFEEIEITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLP 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 471 SGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVGLTAYVAKDPE-TGETVLESGALVLSDRGICCID 549
Cdd:COG1241 308 DGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGGLACID 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 550 EFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGSRYNPRLSVIENIHLPPTLLSRFDLIYLILDKP 629
Cdd:COG1241 388 ELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKP 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 630 DEQTDRRLAKHIVALH---------FENAESAQEEAIDITTLTTYVSYARKNIHPKLSDEAAEELTRGYVELRKAGkfaG 700
Cdd:COG1241 468 DEERDRELARHILKVHragelleqeIEEETEEVKPEIDPDLLRKYIAYARRNVFPVLTEEAKDLIEDFYVDMRKKG---E 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 701 SSKKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRVAMQQSATDHATGTIDMDLINTGVSASERMRRDTF 780
Cdd:COG1241 545 DEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVDPETGKFDIDVIETGTSKSQRDKMKLI 624
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 42569072 781 ASSIRDIALEkmqiGGSSMRLSELLEELKKHGgninteIHLHDVRKAVATLASEGFL 837
Cdd:COG1241 625 KDIIKELEEE----SSGGAPIEDVIEEAEEEG------IDREKAEELIEKLKRKGEI 671
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
144-835 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 631.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 144 FREARENSDDLFREGKYMVSIRKVIEIEGEWIDVDAFDVFDYDPDLYNKMVRYPLEVLAIFDIVLMDIVSTINRLFEK-- 221
Cdd:NF040949 5 FKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEYAEev 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 222 -HVQVRIFNLRTSTSMRNLNPSDIEKMISLKGMIIRSSSIIPEIREAVFRCLVCGY-FSDPIIVDRG-KISEPPT-CLkq 297
Cdd:NF040949 85 aKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCeFEWPEEEEESyEIVEPPTvCP-- 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 298 ECMTKNSMTLVHNRCRFADKQIVRLQETPDEIPEGGTPHTVSLLLHDKLVDNGKPGDRIEVTGIYRamTVRVGPAHRTVK 377
Cdd:NF040949 163 VCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILR--IKPDSSLKKGSR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 378 SVFKTYIDCLHIKKASKlrmsaedpmdvdnslrrVDEDVELDEEKLRKFQELSKQPDIYERLSRSLAPNIWELDDVKKGL 457
Cdd:NF040949 241 PIFKNYIEANHIEVSQK-----------------ELEEVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAI 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 458 LCQLFGGNALNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVGLTAYVAKDPETGETVLESGA 537
Cdd:NF040949 304 ALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGA 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 538 LVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGSRYNPRLSVIENIHLPPTLLS 617
Cdd:NF040949 384 LVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILS 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 618 RFDLIYLILDKPDEQTDRRLAKHIVALHFEnaESAQEEAIDITTLTTYVSYARKNIHPKLSDEAAEELTRGYVELRKAGK 697
Cdd:NF040949 464 RFDLIFVIRDKPNEERDRRLARHILDVHSG--KEKVKPEIDPDLLKKYIAYARKYVRPKLTEEAKKLIEDFYVEMRKSSK 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 698 FAGSSKKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRVAMQQSATDHATGTIDMDLINTGVSASERMRR 777
Cdd:NF040949 542 SSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLESVGIDVETGKIDIDTIMTGKPKSKREKM 621
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*...
gi 42569072 778 DTFASSIRDIALEKMQIggssmRLSELLEELKKHGgnINTEihlhDVRKAVATLASEG 835
Cdd:NF040949 622 SKIVEIIKELEEEEECV-----KIKELIKEAEKKG--IDEE----KVEELISDLKRSG 668
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
438-747 |
0e+00 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 581.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 438 RLSRSLAPNIWELDDVKKGLLCQLFGGNALNLAS-GANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAV 516
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFTKtGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 517 GLTAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSG 596
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 597 SRYNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRLAKHIVALHFENA-ESAQEEAIDITTLTTYVSYARKNIHP 675
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTpEHIQDEVLDVEVLTDYISYAREHIHP 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 42569072 676 KLSDEAAEELTRGYVELRKAGKFAGsskKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRVA 747
Cdd:cd17755 241 KLSEEAAQELVQAYVDMRKMGSDAR---KRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
176-810 |
9.95e-174 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 525.71 E-value: 9.95e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 176 DVDAFDVFDYDPDLYNKMVRYPLEVLAIFDIVLmdiVSTINRLFEKHV------------QVRIFNLRTSTSMRNLNPSD 243
Cdd:PTZ00111 149 EVDLMHVYSFDKVLYKLLVTFPADCIAELDKVL---VKLFNELLSKHYsdlslennsffpRARLMNKPVSDCVGNLEPSM 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 244 IEKMISLKGMIIRSSSIIPEIREAVFRC-------------LVCGYFSDPIivdRGKISEPPTClkQECMTKNSMTLVHN 310
Cdd:PTZ00111 226 ADSLVQFSGTVVRQTWIVPEITMACFRCrgqkkiglndyqpCTCEHYEYVI---QGEVNEPLLC--NECNSKYTFELNHN 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 311 RCRFADKQIVRLQETPDEIPEGGTP--------------------HTVSLLLHDKLVDNGKPGDRIEVTGIYRAMTVRVG 370
Cdd:PTZ00111 301 MCVYSTKKIVKLLQSNSSLNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGILKVTPIRTS 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 371 PAHRTVKSVFKTYIDCLHIKKasklrMSAEDPMDVDNSLRRVDEDVELDEEKLRKFQELSKQPDIYERLSRSLAPNIWEL 450
Cdd:PTZ00111 381 TTRRTLKSLYTYFVNVIHVKV-----INSTNANQPEKGLKYLGNENDFSDLQVYKILELSRNPMIYRILLDSFAPSIKAR 455
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 451 DDVKKGLLCQLFGGNA----LNLASGA-----NFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVGLTAY 521
Cdd:PTZ00111 456 NNVKIGLLCQLFSGNKnssdFNKSPDAcykvdNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTAS 535
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 522 VA-KDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGSRYN 600
Cdd:PTZ00111 536 IKfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYN 615
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 601 PRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRR----LAKHIVALHFENAESA------------QEEAI------- 657
Cdd:PTZ00111 616 KNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLislsIAKDFLLPHMTGSGNDedtydrsntmhvEDESLrsekdyn 695
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 658 --DITTLTTYVSYARKNIHPKLSDEAAEELTRGYVELRKAG--------------------KFAGSSKKVITATPRQIES 715
Cdd:PTZ00111 696 knDLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNfqtsnldelehaqedddddlYYQSSGTRMIYVSSRMISS 775
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 716 LIRLSEALARMRFSEWVEKHDVDEAFRLLRVAMQQSATDHATGTIDMDLINTGVSASERMRRDTFASSIRD-IALEKMQI 794
Cdd:PTZ00111 776 IIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVDPTTGKIDFDQLHQGITTNKMQQLNQMYEQVLSvLTRSSNQD 855
|
730
....*....|....*.
gi 42569072 795 GGSSMRLSELLEELKK 810
Cdd:PTZ00111 856 SNKSLDLNEVLSLCHK 871
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
438-747 |
6.10e-145 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 429.84 E-value: 6.10e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 438 RLSRSLAPNIWELDDVKKGLLCQLFGGNALNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVG 517
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 518 LTAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGS 597
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 598 RYNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRLAKHIVALHFENAES------AQEEAIDITTLTTYVSYARK 671
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDPEeqvkpeEDGIPIDIELLRKYILYARQ 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 42569072 672 nIHPKLSDEAAEELTRGYVELRKAGKfagsSKKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRVA 747
Cdd:cd17706 241 -IHPKISEEAREKLVRWYVELRKESE----RRSTIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
438-747 |
5.00e-139 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 414.50 E-value: 5.00e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 438 RLSRSLAPNIWELDDVKKGLLCQLFGGNAlNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVG 517
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVD-KRGDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 518 LTAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGS 597
Cdd:cd17758 80 LTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 598 RYNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRLAKHIVALHFENAESAQE-EAIDITTLTTYVSYArKNIHPK 676
Cdd:cd17758 160 RYNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQHNKQPDSDfEPLDPKLLRAYIALA-KRKRPT 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 42569072 677 LSDEAAEELTRGYVELRKAgkfAGSSKKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRVA 747
Cdd:cd17758 239 VPPALADYIVQAYVEMRQE---AKRSKDFTFTTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
423-645 |
1.69e-137 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 406.92 E-value: 1.69e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 423 LRKFQELSKQPDIYERLSRSLAPNIWELDDVKKGLLCQLFGGNALNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLS 502
Cdd:pfam00493 2 EEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 503 PRGIYTSGRGSSAVGLTAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASL 582
Cdd:pfam00493 82 PRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATL 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 42569072 583 NARTSVLACANPSGSRYNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRLAKHIVALH 645
Cdd:pfam00493 162 NARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
438-745 |
8.44e-132 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 395.58 E-value: 8.44e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 438 RLSRSLAPNIWELDDVKKGLLCQLFGGNALNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVG 517
Cdd:cd17757 1 NLVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 518 LTAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGS 597
Cdd:cd17757 81 LTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 598 RYNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRLAKHIVALHfENAESAQEEAIDITTLTTYVSYARKnIHPKL 677
Cdd:cd17757 161 RYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLH-SKREEAIEPPFTAEQLKRYIAYART-FKPKL 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 42569072 678 SDEAAEELTRGYVELRKaGKFAGSSKKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLR 745
Cdd:cd17757 239 TKEAKDELVEQYKELRQ-DDASGSTRSSYRITVRQLESLIRLSEAIARLHCSDEVTPEHVEEAARLLK 305
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
437-745 |
8.02e-131 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 393.36 E-value: 8.02e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 437 ERLSRSLAPNIWELDDVKKGLLCQLFGGNALNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAV 516
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 517 GLTAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSG 596
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 597 SRYNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRLAKHIVALHFENAESAQEEAIDITTLTTYVSYARKNIHPK 676
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGEMREIKPEIDPDLLRKYIAYARKNVRPV 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 42569072 677 LSDEAAEELTRGYVELRKAGKfagSSKKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLR 745
Cdd:cd17761 241 LTEEAKQLIKDFYVEMRKSGQ---ETPSPVPITARQLEALVRLSEASARMRLSQEVTLEDAERAIRIML 306
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
438-746 |
1.86e-126 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 382.50 E-value: 1.86e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 438 RLSRSLAPNIWELDDVKKGLLCQLFGGNALNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVG 517
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 518 LTAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGS 597
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 598 RYNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRLAKHIVALHFENAESAQEEA----IDITTLTTYVSYARKNI 673
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQSQEnegeIPISKLKRYIAYCRAKC 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 42569072 674 HPKLSDEAAEELTRGYVELRK---AGKFAGSSKKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRV 746
Cdd:cd17756 241 APRLSEEAAEKLSNHYVTIRKdvrQNELESDNRSSIPITVRQLEAIIRISESLAKMELSPIATEKHVEEAIRLFQV 316
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
439-747 |
1.11e-116 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 356.39 E-value: 1.11e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 439 LSRSLAPNIWELDDVKKGLLCQLFGGNALNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVGL 518
Cdd:cd17754 2 LSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 519 TAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGSR 598
Cdd:cd17754 82 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 599 YNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRLAKHIVALHFENAesaqeeaiditTLTTYVSYARKNIHPKLS 678
Cdd:cd17754 162 YDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRYIK-----------FLRKYIHYAKERIKPKLT 230
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 42569072 679 DEAAEELTRGYVELRKAGKFAGSSKKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRVA 747
Cdd:cd17754 231 QEAAEYIAEEYADLRNDDNTKTDKARTSPITARTLETLIRLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
438-744 |
6.38e-114 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 350.21 E-value: 6.38e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 438 RLSRSLAPNIWELDDVKKGLLCQLFGGNALNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVG 517
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 518 LTAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGS 597
Cdd:cd17753 81 LTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 598 RYNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRLAKHIVALHFENAESAQE-------------------EAID 658
Cdd:cd17753 161 RYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHPENDEdregeeeknqrqrpketkvEPIP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 659 ITTLTTYVSYARKNIHPKLSDEAAEELTRGYVELRKAGKFAGSskkvITATPRQIESLIRLSEALARMRFSEWVEKHDVD 738
Cdd:cd17753 241 QELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGS----LPITVRHLESIIRISEAHAKMHLREYVSEEDVD 316
|
....*.
gi 42569072 739 EAFRLL 744
Cdd:cd17753 317 MAIRVM 322
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
438-745 |
7.50e-90 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 285.58 E-value: 7.50e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 438 RLSRSLAPNIWELDDVKKGLLCQLFGG--NALNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSA 515
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGkqKYADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 516 VGLTAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLhEVMEQQTVSIAKAGIIASLNARTSVLACANPS 595
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGSQHQALL-EAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 596 GSRYNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDrrlakHIVALHFEnaesaqeeaiditTLTTYVSYARKNIHP 675
Cdd:cd17759 160 GGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHD-----HLLSEHHQ-------------LLRKYISYARQYVNP 221
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 676 KLSDEAAEELTRGYVELRKAGKFAGSSKkvITAtpRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLR 745
Cdd:cd17759 222 VLSKDASEALQEFYLELRKQNQLADSSP--ITT--RQLESLIRLTEARARLELREEATKEDAEDVIEIMK 287
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
441-747 |
3.67e-77 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 252.47 E-value: 3.67e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 441 RSLAPNIWELDDVKKGLLCQLFGGNALNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVGLTA 520
Cdd:cd17760 4 ASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAGLTV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 521 YVAKDpeTGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGsRYN 600
Cdd:cd17760 84 TAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKG-QYD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 601 PRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRLAKHIVALHFENAESaqEEAIDITTLTTYVSYArKNIHPKLSDE 680
Cdd:cd17760 161 PNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFILENKGEPSKS--SKLWSMEKMRTYFCLI-KNLRPVLSDE 237
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 42569072 681 AAEELTRGYVELRKAgkfagSSKKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRVA 747
Cdd:cd17760 238 ANAILLRYYQLQRQS-----DCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
235-365 |
9.94e-51 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 173.82 E-value: 9.94e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 235 SMRNLNPSDIEKMISLKGMIIRSSSIIPEIREAVFRCLVCGYFsdpIIVdrgKISEPPTCLKQECMTKNSMTLVHNRCRF 314
Cdd:pfam17207 1 SIRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHT---VGV---KITEPTKCPNPECGNKDPFKLVHEKSKF 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 42569072 315 ADKQIVRLQETPDEIPEGGTPHTVSLLLHDKLVDNGKPGDRIEVTGIYRAM 365
Cdd:pfam17207 75 VDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVV 125
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
660-748 |
7.88e-32 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 118.80 E-value: 7.88e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 660 TTLTTYVSYARKNIHPKLSDEAAEELTRGYVELRKAgkfAGSSKKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDE 739
Cdd:pfam17855 1 ELLRKYIAYAREKIKPKLSEEAREKLVDAYVELRKE---STGSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEE 77
|
....*....
gi 42569072 740 AFRLLRVAM 748
Cdd:pfam17855 78 AIRLLKESL 86
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
140-229 |
1.46e-12 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 64.24 E-value: 1.46e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 140 FVKHFREARENsddlfrEGKYMVSIRKVIEIEGEWIDVDAFDVFDYDPDLYNKMVRYPLEVLAIFDIVLMDIVSTI---- 215
Cdd:pfam14551 7 FLEEFREDGDG------EFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKELsedp 80
|
90
....*....|....*
gi 42569072 216 -NRLFEKHVQVRIFN 229
Cdd:pfam14551 81 dYAEEEKEFQVRFYN 95
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
480-619 |
3.82e-08 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 52.68 E-value: 3.82e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 480 NILLVGDPGTSKSQLLQYI-HKLSPRGIYTsgrgssaVGLTAYVAKD-------PETGETVLESGALVLSDR--GICCID 549
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLaAALSNRPVFY-------VQLTRDTTEEdlfgrrnIDPGGASWVDGPLVRAARegEIAVLD 73
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 42569072 550 EFDKMSDSARSMLHEVMEQQTVSIAKAG-IIASLNARTSVLACANPSGSRYNPrlsvienihLPPTLLSRF 619
Cdd:pfam07728 74 EINRANPDVLNSLLSLLDERRLLLPDGGeLVKAAPDGFRLIATMNPLDRGLNE---------LSPALRSRF 135
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
481-744 |
3.79e-06 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 49.40 E-value: 3.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 481 ILLVGDPGTSKSQLLQYIHK---LSPRGIY-TSG-RGSSAVGLTAYvakDPETGETVLESGAL----VLsdrgiccIDEF 551
Cdd:COG0714 34 LLLEGVPGVGKTTLAKALARalgLPFIRIQfTPDlLPSDILGTYIY---DQQTGEFEFRPGPLfanvLL-------ADEI 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 552 DKMSDSARSMLHEVMEQQTVSIAKAGIiaSLNARTSVLACANPsgsrynprlsvIENI---HLPPTLLSRFdLIYLILDK 628
Cdd:COG0714 104 NRAPPKTQSALLEAMEERQVTIPGGTY--KLPEPFLVIATQNP-----------IEQEgtyPLPEAQLDRF-LLKLYIGY 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 629 PDEQTDRRlakhIVALHFENAESAQEEAIDITTLTTYVSYARK-NIHPKLSDEAAE--ELTRGYVELRKagkfaGSSkkv 705
Cdd:COG0714 170 PDAEEERE----ILRRHTGRHLAEVEPVLSPEELLALQELVRQvHVSEAVLDYIVDlvRATREHPDLRK-----GPS--- 237
|
250 260 270
....*....|....*....|....*....|....*....
gi 42569072 706 itatPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLL 744
Cdd:COG0714 238 ----PRASIALLRAARALALLDGRDYVTPDDVKAVAGPV 272
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
480-622 |
4.16e-06 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 47.53 E-value: 4.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569072 480 NILLVGDPGTSKSQLLQYIHKLSPRG----IYTSGrgsSAVGLTAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMS 555
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFRPgapfLYLNA---SDLLEGLVVAELFGHFLVRLLFELAEKAKPGVLFIDEIDSLS 97
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 42569072 556 DSARSMLHEVMEQQTVSIAKagiiaslNARTSVLACANPSgsrynprlsviENIHLPPTLLSRFDLI 622
Cdd:cd00009 98 RGAQNALLRVLETLNDLRID-------RENVRVIGATNRP-----------LLGDLDRALYDRLDIR 146
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
2-76 |
3.36e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 41.31 E-value: 3.36e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 42569072 2 ASDSSLGNTNDGPPSPGENVSSPIENTYSSPAALHRRRRGRSSTPTQFATPPPPPSRLASSNSTPPTSRPSAARS 76
Cdd:PHA03307 299 SPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSR 373
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
2-76 |
6.78e-03 |
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transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 40.15 E-value: 6.78e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 42569072 2 ASDSSLGNTNDGPPSPGEnVSSPIENTYSSPAALHRRRRGRSSTPTqfATPPPPPSRLASSNSTPPTSRPSAARS 76
Cdd:PHA03307 314 ASSSSSSSRESSSSSTSS-SSESSRGAAVSPGPSPSRSPSPSRPPP--PADPSSPRKRPRPSRAPSSPAASAGRP 385
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