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Conserved domains on  [gi|15226916|ref|NP_180431|]
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3-ketoacyl-CoA synthase 12 [Arabidopsis thaliana]

Protein Classification

type III polyketide synthase( domain architecture ID 10552001)

type III polyketide synthase, similar to chalcone and stilbene synthase, which are involved in the synthesis of chalcone or stilbene, respectively, by catalyzing the addition of three molecules of malonyl-CoA to a starter CoA ester

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FAE1_CUT1_RppA pfam08392
FAE1/Type III polyketide synthase-like protein; The members of this family are described as ...
 23-305 5.06e-158

FAE1/Type III polyketide synthase-like protein; The members of this family are described as 3-ketoacyl-CoA synthases, type III polyketide synthases, fatty acid elongases and fatty acid condensing enzymes, and are found in both prokaryotic and eukaryotic (mainly plant) species. The region featured in this family contains the active site residues, as well as motifs involved in substrate binding.


:

Pssm-ID: 429970  Cd Length: 290  Bit Score: 449.39  E-value: 5.06e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916    23 IDSKQDKDCYILDYQCHKPTDDRMVSTQFSGEIIYRNQNLGLTEYKFLLKAIVSSGIGEQTYAPRLVFEGREeRPSLQDG 102
Cdd:pfam08392   1 YLARRPRPVYLVDYSCYKPPDDRKVSTETFMEHIQRNGHLDLESLDFQRKILERSGLGEETYLPRAVLEGPP-DPTLAEA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   103 ISEMEEFYVDSIGKLLERNQISPKDIDILVVNVSMLSSTPSLASRIINHYKMRDDVKVFNLTGMGCSASLISVDIVKNIF 182
Cdd:pfam08392  80 REEAEEVIFGAVDDLFAKTGVSPRDIDILVVNCSLFNPTPSLSAMIVNRYKLRSDIKSYNLSGMGCSAGLISIDLAKNLL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   183 KSYANKLALVATSESLSPNWYSGNNRSMILANCLFRSGGCAILLTNKRSLRKKAMFKLKCMVRTHHGAREESYNCCIQAE 262
Cdd:pfam08392 160 QVHPNTYALVVSTENITPNWYFGNDRSMLLPNCLFRMGGAAVLLSNRPADRRRAKYELVHTVRTHKGADDRAYNCVYQEE 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 15226916   263 DEQGRVGFYLGKNLPKAATRAFVENLKVITPKILPVTELIRFM 305
Cdd:pfam08392 240 DEDGKVGVSLSKDLMKVAGRALKTNITTLGPLVLPLSEQLRFA 282
Ketoacyl-synt_C super family cl21486
Beta-ketoacyl synthase, C-terminal domain; The structure of beta-ketoacyl synthase is similar ...
 333-423 2.74e-13

Beta-ketoacyl synthase, C-terminal domain; The structure of beta-ketoacyl synthase is similar to that of the thiolase family (pfam00108) and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains.


The actual alignment was detected with superfamily member pfam08541:

Pssm-ID: 451266  Cd Length: 90  Bit Score: 65.21  E-value: 2.74e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   333 KAGINfKTGIEHFCIHTGGKAVIDGIGHSLDLNEydiEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFG 412
Cdd:pfam08541   3 KAGLT-PEDIDWFVPHQANLRIIDAVAKRLGLPP---EKVVVNLDEYGNTSAASIPLALDEAVEEGKLKPGDLVLLVGFG 78

                          90
                  ....*....|.
gi 15226916   413 AGFKCNSCVWE 423
Cdd:pfam08541  79 AGLTWGAALLR 89
 
Name Accession Description Interval E-value
FAE1_CUT1_RppA pfam08392
FAE1/Type III polyketide synthase-like protein; The members of this family are described as ...
 23-305 5.06e-158

FAE1/Type III polyketide synthase-like protein; The members of this family are described as 3-ketoacyl-CoA synthases, type III polyketide synthases, fatty acid elongases and fatty acid condensing enzymes, and are found in both prokaryotic and eukaryotic (mainly plant) species. The region featured in this family contains the active site residues, as well as motifs involved in substrate binding.


Pssm-ID: 429970  Cd Length: 290  Bit Score: 449.39  E-value: 5.06e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916    23 IDSKQDKDCYILDYQCHKPTDDRMVSTQFSGEIIYRNQNLGLTEYKFLLKAIVSSGIGEQTYAPRLVFEGREeRPSLQDG 102
Cdd:pfam08392   1 YLARRPRPVYLVDYSCYKPPDDRKVSTETFMEHIQRNGHLDLESLDFQRKILERSGLGEETYLPRAVLEGPP-DPTLAEA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   103 ISEMEEFYVDSIGKLLERNQISPKDIDILVVNVSMLSSTPSLASRIINHYKMRDDVKVFNLTGMGCSASLISVDIVKNIF 182
Cdd:pfam08392  80 REEAEEVIFGAVDDLFAKTGVSPRDIDILVVNCSLFNPTPSLSAMIVNRYKLRSDIKSYNLSGMGCSAGLISIDLAKNLL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   183 KSYANKLALVATSESLSPNWYSGNNRSMILANCLFRSGGCAILLTNKRSLRKKAMFKLKCMVRTHHGAREESYNCCIQAE 262
Cdd:pfam08392 160 QVHPNTYALVVSTENITPNWYFGNDRSMLLPNCLFRMGGAAVLLSNRPADRRRAKYELVHTVRTHKGADDRAYNCVYQEE 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 15226916   263 DEQGRVGFYLGKNLPKAATRAFVENLKVITPKILPVTELIRFM 305
Cdd:pfam08392 240 DEDGKVGVSLSKDLMKVAGRALKTNITTLGPLVLPLSEQLRFA 282
PLN02854 PLN02854
3-ketoacyl-CoA synthase
 25-448 1.61e-135

3-ketoacyl-CoA synthase


Pssm-ID: 215459  Cd Length: 521  Bit Score: 400.87  E-value: 1.61e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   25 SKQDKDCYILDYQCHKPTDDRMVSTQFSGEIIYRNQNLGLTEYKFLLKAIVSSGIGEQTYAPRlvfeGREERP---SLQD 101
Cdd:PLN02854 108 AKRSKPVYLVDFACYKPEDERKISVDSFLTMTEENGSFEDETVQFQRRISTRSGLGDETYLPR----GITSRPpnlCMEE 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  102 GISEMEEFYVDSIGKLLERNQISPKDIDILVVNVSMLSSTPSLASRIINHYKMRDDVKVFNLTGMGCSASLISVDIVKNI 181
Cdd:PLN02854 184 ARAEAEAVMFGALDSLFSKTGVKPRDIGILIVNCSLFNPTPSLSAMIVNHYKLRTDIKSYNLGGMGCSAGLISIDLANDL 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  182 FKSYANKLALVATSESLSPNWYSGNNRSMILANCLFRSGGCAILLTNKRSLRKKAMFKLKCMVRTHHGAREESYNCCIQA 261
Cdd:PLN02854 264 LKANPNSYAVVVSTENITLNWYFGNDRSMLLCNCIFRMGGAAVLLSNKARDRKRSKYQLVHTVRTHKGADDKNYNCVYQR 343

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  262 EDEQGRVGFYLGKNLPKAATRAFVENLKVITPKILPVTELIRFMlkllikKIKIRQNPSKgsTNLPPGTPlkagiNFKTG 341
Cdd:PLN02854 344 EDDKGTIGVSLARELMAVAGDALKTNITTLGPLVLPLSEQFMFF------VTLVRRKLLK--AKVKPYIP-----DFKLA 410

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  342 IEHFCIHTGGKAVIDGIGHSLDLNEYDIEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGAGFKCNSCV 421
Cdd:PLN02854 411 FEHFCIHAGGRAVLDELQKNLQLSDWHMEPSRMTLHRFGNTSSSSLWYELAYTEAKGRVSAGDRVWQIAFGSGFKCNSAV 490

                        410       420
                 ....*....|....*....|....*..
gi 15226916  422 WEVVRDLTGGESKGNVWNHCIDDYPPK 448
Cdd:PLN02854 491 WKALREIPTGESTGNPWADSIDRYPVK 517
CHS_like cd00831
Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, ...
 31-422 2.94e-113

Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, also called type III PKSs. PKS generate an array of different products, dependent on the nature of the starter molecule. They share a common chemical strategy, after the starter molecule is loaded onto the active site cysteine, a carboxylative condensation reation extends the polyketide chain. Plant-specific PKS are dimeric iterative PKSs, using coenzyme A esters to deliver substrate to the active site, but they differ in the choice of starter molecule and the number of condensation reactions.


Pssm-ID: 238427 [Multi-domain]  Cd Length: 361  Bit Score: 338.04  E-value: 2.94e-113
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  31 CYILDYQCHKPTDDRMVSTQFSGEIIYRNqnLGLTEYKFLLKaivssgIGEQTYAPRLvFEGREERPSLQDGISEMEEFY 110
Cdd:cd00831  19 SELVDFYRRLFSSDHLPELKEKLKRLCAK--TGIETRYLVLP------GGEETYAPRP-EMSPSLDERNDIALEEARELA 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 111 VDSIGKLLERNQISPKDIDILVVNVSMLSSTPSLASRIINHYKMRDDVKVFNLTGMGCSASLISVDIVKNIFKSYANKLA 190
Cdd:cd00831  90 EEAARGALDEAGLRPSDIDHLVVNTSTGNPTPSLDAMLINRLGLRPDVKRYNLGGMGCSAGAIALDLAKDLLEANPGARV 169

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 191 LVATSESLSPnWYSGNN-RSMILANCLFRSGGCAILLTNKRSLRKKamfklkcmvRTHHGAREESYNCCIQaeDEQGRVG 269
Cdd:cd00831 170 LVVSTELCSL-WYRGPDhRSMLVGNALFGDGAAAVLLSNDPRDRRR---------ERPLFELVRAASTLLP--DSEDAMG 237

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 270 FYLGKnlpkaatrafvENLKVITPKilPVTELIRFMLKLLIKKIKIRqnpskgstnlppgtplKAGINFKTGIEHFCIHT 349
Cdd:cd00831 238 WHLGE-----------EGLTFVLSR--DVPRLVEKNLERVLRKLLAR----------------LGIGLFKLAFDHWCVHP 288

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15226916 350 GGKAVIDGIGHSLDLNEYDIEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGAGFKCNSCVW 422
Cdd:cd00831 289 GGRAVLDAVEKALGLSPEDLEASRMVLRRYGNMSSSSVLYVLAYMEAKGRVKRGDRGLLIAFGPGFTCESAVW 361
BH0617 COG3424
Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport and ...
 111-415 5.58e-28

Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442650 [Multi-domain]  Cd Length: 351  Bit Score: 114.08  E-value: 5.58e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 111 VDSIGKLLERNQISPKDIDILVVNvsmlSST----PSLASRIINHYKMRDDVKVFNLTGMGCSASLISVDIVKNIFKSYA 186
Cdd:COG3424  82 EEAARRALDKAGLDPEDIDHLVTV----SCTgfaaPGLDARLINRLGLRPDVRRLPVGGMGCAAGAAGLRRAADFLRADP 157

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 187 NKLALVATSESLS----PNWYSGNNrsmILANCLFRSGGCAILLTNKRslrkkamfklkcmvRTHHGAR-EESYNCCI-Q 260
Cdd:COG3424 158 DAVVLVVCVELCSltfqRDDDSKDN---LVANALFGDGAAAVVVSGDP--------------RPGPGPRiLAFRSYLIpD 220

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 261 AEDEQG-RVG-----FYLGKNLPKAATRAFVENLkvitpkilpvtelirfmlkllikkikirqnpskgstnlppgTPLKA 334
Cdd:COG3424 221 TEDVMGwDVGdtgfrMVLSPEVPDLIAEHLAPAV-----------------------------------------EPLLA 259

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 335 GINFKTG-IEHFCIHTGGKAVIDGIGHSLDLNEYDIEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGA 413
Cdd:COG3424 260 RHGLTIEdIDHWAVHPGGPKVLDAVEEALGLPPEALAHSREVLREYGNMSSATVLFVLERLLEEGAPAPGERGLAMAFGP 339


                ..
gi 15226916 414 GF 415
Cdd:COG3424 340 GF 341
ACP_syn_III_C pfam08541
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on ...
 333-423 2.74e-13

3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.41, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.


Pssm-ID: 430060  Cd Length: 90  Bit Score: 65.21  E-value: 2.74e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   333 KAGINfKTGIEHFCIHTGGKAVIDGIGHSLDLNEydiEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFG 412
Cdd:pfam08541   3 KAGLT-PEDIDWFVPHQANLRIIDAVAKRLGLPP---EKVVVNLDEYGNTSAASIPLALDEAVEEGKLKPGDLVLLVGFG 78

                          90
                  ....*....|.
gi 15226916   413 AGFKCNSCVWE 423
Cdd:pfam08541  79 AGLTWGAALLR 89
PRK09352 PRK09352
beta-ketoacyl-ACP synthase 3;
355-415 5.58e-08

beta-ketoacyl-ACP synthase 3;


Pssm-ID: 236475 [Multi-domain]  Cd Length: 319  Bit Score: 54.31  E-value: 5.58e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15226916  355 IDGIGHSLDLneyDIEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGAGF 415
Cdd:PRK09352 252 IDATAKKLGL---PMEKVVVTVDKYGNTSAASIPLALDEAVRDGRIKRGDLVLLEGFGGGL 309
 
Name Accession Description Interval E-value
FAE1_CUT1_RppA pfam08392
FAE1/Type III polyketide synthase-like protein; The members of this family are described as ...
 23-305 5.06e-158

FAE1/Type III polyketide synthase-like protein; The members of this family are described as 3-ketoacyl-CoA synthases, type III polyketide synthases, fatty acid elongases and fatty acid condensing enzymes, and are found in both prokaryotic and eukaryotic (mainly plant) species. The region featured in this family contains the active site residues, as well as motifs involved in substrate binding.


Pssm-ID: 429970  Cd Length: 290  Bit Score: 449.39  E-value: 5.06e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916    23 IDSKQDKDCYILDYQCHKPTDDRMVSTQFSGEIIYRNQNLGLTEYKFLLKAIVSSGIGEQTYAPRLVFEGREeRPSLQDG 102
Cdd:pfam08392   1 YLARRPRPVYLVDYSCYKPPDDRKVSTETFMEHIQRNGHLDLESLDFQRKILERSGLGEETYLPRAVLEGPP-DPTLAEA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   103 ISEMEEFYVDSIGKLLERNQISPKDIDILVVNVSMLSSTPSLASRIINHYKMRDDVKVFNLTGMGCSASLISVDIVKNIF 182
Cdd:pfam08392  80 REEAEEVIFGAVDDLFAKTGVSPRDIDILVVNCSLFNPTPSLSAMIVNRYKLRSDIKSYNLSGMGCSAGLISIDLAKNLL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   183 KSYANKLALVATSESLSPNWYSGNNRSMILANCLFRSGGCAILLTNKRSLRKKAMFKLKCMVRTHHGAREESYNCCIQAE 262
Cdd:pfam08392 160 QVHPNTYALVVSTENITPNWYFGNDRSMLLPNCLFRMGGAAVLLSNRPADRRRAKYELVHTVRTHKGADDRAYNCVYQEE 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 15226916   263 DEQGRVGFYLGKNLPKAATRAFVENLKVITPKILPVTELIRFM 305
Cdd:pfam08392 240 DEDGKVGVSLSKDLMKVAGRALKTNITTLGPLVLPLSEQLRFA 282
PLN02854 PLN02854
3-ketoacyl-CoA synthase
 25-448 1.61e-135

3-ketoacyl-CoA synthase


Pssm-ID: 215459  Cd Length: 521  Bit Score: 400.87  E-value: 1.61e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   25 SKQDKDCYILDYQCHKPTDDRMVSTQFSGEIIYRNQNLGLTEYKFLLKAIVSSGIGEQTYAPRlvfeGREERP---SLQD 101
Cdd:PLN02854 108 AKRSKPVYLVDFACYKPEDERKISVDSFLTMTEENGSFEDETVQFQRRISTRSGLGDETYLPR----GITSRPpnlCMEE 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  102 GISEMEEFYVDSIGKLLERNQISPKDIDILVVNVSMLSSTPSLASRIINHYKMRDDVKVFNLTGMGCSASLISVDIVKNI 181
Cdd:PLN02854 184 ARAEAEAVMFGALDSLFSKTGVKPRDIGILIVNCSLFNPTPSLSAMIVNHYKLRTDIKSYNLGGMGCSAGLISIDLANDL 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  182 FKSYANKLALVATSESLSPNWYSGNNRSMILANCLFRSGGCAILLTNKRSLRKKAMFKLKCMVRTHHGAREESYNCCIQA 261
Cdd:PLN02854 264 LKANPNSYAVVVSTENITLNWYFGNDRSMLLCNCIFRMGGAAVLLSNKARDRKRSKYQLVHTVRTHKGADDKNYNCVYQR 343

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  262 EDEQGRVGFYLGKNLPKAATRAFVENLKVITPKILPVTELIRFMlkllikKIKIRQNPSKgsTNLPPGTPlkagiNFKTG 341
Cdd:PLN02854 344 EDDKGTIGVSLARELMAVAGDALKTNITTLGPLVLPLSEQFMFF------VTLVRRKLLK--AKVKPYIP-----DFKLA 410

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  342 IEHFCIHTGGKAVIDGIGHSLDLNEYDIEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGAGFKCNSCV 421
Cdd:PLN02854 411 FEHFCIHAGGRAVLDELQKNLQLSDWHMEPSRMTLHRFGNTSSSSLWYELAYTEAKGRVSAGDRVWQIAFGSGFKCNSAV 490

                        410       420
                 ....*....|....*....|....*..
gi 15226916  422 WEVVRDLTGGESKGNVWNHCIDDYPPK 448
Cdd:PLN02854 491 WKALREIPTGESTGNPWADSIDRYPVK 517
PLN02192 PLN02192
3-ketoacyl-CoA synthase
 32-446 2.61e-124

3-ketoacyl-CoA synthase


Pssm-ID: 215123  Cd Length: 511  Bit Score: 372.00  E-value: 2.61e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   32 YILDYQCHKPTDDRMVSTQFsgeIIYRNQNLG-LTE--YKFLLKAIVSSGIGEQTYAPRLVFEgREERPSLQDGISEMEE 108
Cdd:PLN02192 103 YLVDFSCYKPDDSRKCTRKI---FMDRSKLTGsFTEenLEFQRKILERSGLGESTYLPEAVLN-VPPNPCMAEARKEAET 178

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  109 FYVDSIGKLLERNQISPKDIDILVVNVSMLSSTPSLASRIINHYKMRDDVKVFNLTGMGCSASLISVDIVKNIFKSYANK 188
Cdd:PLN02192 179 VMFGAIDQLLAKTSVKPKDIGILIVNCSLFNPTPSLSAMVINHYKLRGNILSYNLGGMGCSAGLISIDLAKHLLQVHPNS 258

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  189 LALVATSESLSPNWYSGNNRSMILANCLFRSGGCAILLTNKRSLRKKAMFKLKCMVRTHHGAREESYNCCIQAEDEQGRV 268
Cdd:PLN02192 259 YALVISMENITLNWYFGNDRSMLVSNCLFRMGGAAILLSNKRSDRRRSKYQLVHTVRTHKGADDKCFACVTQEEDSAGKI 338

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  269 GFYLGKNLPKAATRAFVENLKVITPKILPVTELIRFMLKLLIKKIKIRQnpskgstnLPPGTPlkagiNFKTGIEHFCIH 348
Cdd:PLN02192 339 GVSLSKDLMAVAGDALKTNITTLGPLVLPMSEQLLFFATLVGKKLFKMK--------LKPYIP-----DFKLAFEHFCIH 405

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  349 TGGKAVIDGIGHSLDLNEYDIEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGAGFKCNSCVWEVVRDL 428
Cdd:PLN02192 406 AGGRAVLDELEKNLQLSDWHMEPSRMTLYRFGNTSSSSLWYELAYSEAKGRIKKGDRTWQIAFGSGFKCNSAVWKALRTV 485

                        410
                 ....*....|....*...
gi 15226916  429 TGGESKgNVWNHCIDDYP 446
Cdd:PLN02192 486 NPAKEK-NPWMDEIHEFP 502
PLN02932 PLN02932
3-ketoacyl-CoA synthase
 19-446 6.66e-119

3-ketoacyl-CoA synthase


Pssm-ID: 178520  Cd Length: 478  Bit Score: 356.65  E-value: 6.66e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   19 IWKLIDSKQDKDCYILDYQCHKPTDDRMVSTQFSGEIIYRNQNLGL----TEY--KFLLKAIVSSGIGEQTYAPrlvfEG 92
Cdd:PLN02932  56 GSTLYLMTRPKPVYLVDFSCYLPPSHLKASIQTIMGHVRRVREAGAwkqeSDYlmDFCEKILERSGLGQETYIP----EG 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   93 REERPsLQDGIS----EMEEFYVDSIGKLLERNQISPKDIDILVVNVSMLSSTPSLASRIINHYKMRDDVKVFNLTGMGC 168
Cdd:PLN02932 132 LQCLP-LQQNLAvsrkETEEVIIGAVDNLFRNTGISPSDIGILVVNSSTFNPTPSLSSILVNKFKLRDNIKSLNLGGMGC 210

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  169 SASLISVDIVKNIFKSYANKLALVATSESLSPNWYSGNNRSMILANCLFRSGGCAILLTNKRSLRKKAMFKLKCMVRTHH 248
Cdd:PLN02932 211 SAGVIAIDAAKSLLQVHRNTYALVVSTENITQNLYLGNNKSMLVTNCLFRIGGAAILLSNRSRDRKRAKYELVHTVRVHT 290

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  249 GAREESYNCCIQAEDEQGRVGFYLGKNLPKAATRAFVENLKVITPKILPVTELIRFMLKLLIKKIKirqNPSkgstnLPP 328
Cdd:PLN02932 291 GADDRSYECATQEEDEDGIVGVSLSKNLPMVAARTLKINIATLGPLVLPLSEKFHFFVRFVKKKFF---NPK-----LKH 362

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  329 GTPlkagiNFKTGIEHFCIHTGGKAVIDGIGHSLDLNEYDIEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFM 408
Cdd:PLN02932 363 YIP-----DFKLAFEHFCIHAGGRALIDEMEKNLHLTPLDVEASRMTLHRFGNTSSSSIWYELAYTEAKGRMKKGDRIWQ 437

                        410       420       430
                 ....*....|....*....|....*....|....*...
gi 15226916  409 ISFGAGFKCNSCVWEVVRDLTggESKGNVWNHCIDDYP 446
Cdd:PLN02932 438 IALGSGFKCNSSVWVALRNVK--PSANNPWEDCLHKYP 473
PLN02377 PLN02377
3-ketoacyl-CoA synthase
 32-448 1.76e-115

3-ketoacyl-CoA synthase


Pssm-ID: 166018  Cd Length: 502  Bit Score: 348.93  E-value: 1.76e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   32 YILDYQCHKPTDDR-------MVSTQFSGEiiyrnqnLGLTEYKFLLKAIVSSGIGEQTYAPRlVFEGREERPSLQDGIS 104
Cdd:PLN02377  99 YLVDYSCYRAPDHLkapfarfMEHSRLTGD-------FDDSSLEFQRKILERSGLGEDTYVPE-AMHYIPPRPSMAAARE 170

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  105 EMEEFYVDSIGKLLERNQISPKDIDILVVNVSMLSSTPSLASRIINHYKMRDDVKVFNLTGMGCSASLISVDIVKNIFKS 184
Cdd:PLN02377 171 EAEQVMFGALDNLFANTNVNPKDIGILVVNCSLFNPTPSLSAMIVNKYKLRGNIRSFNLGGMGCSAGVIAVDLAKDMLQV 250

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  185 YANKLALVATSESLSPNWYSGNNRSMILANCLFRSGGCAILLTNKRSLRKKAMFKLKCMVRTHHGAREESYNCCIQAEDE 264
Cdd:PLN02377 251 HRNTYAVVVSTENITQNWYFGNKKSMLIPNCLFRVGGSAVLLSNKSRDKRRSKYKLVHVVRTHRGADDKAFRCVYQEQDD 330

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  265 QGRVGFYLGKNLPKAATRAFVENLKVITPKILPVTELIRFMLKLLIKKIKIRQnpskgstnLPPGTPlkagiNFKTGIEH 344
Cdd:PLN02377 331 AGKTGVSLSKDLMAIAGEALKTNITTLGPLVLPISEQLLFFATLVVKKLFNKK--------MKPYIP-----DFKLAFDH 397

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  345 FCIHTGGKAVIDGIGHSLDLNEYDIEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGAGFKCNSCVWEV 424
Cdd:PLN02377 398 FCIHAGGRAVIDELEKNLQLLPVHVEASRMTLHRFGNTSSSSIWYELAYIEAKGRMRKGNRVWQIAFGSGFKCNSAVWEA 477

                        410       420
                 ....*....|....*....|....
gi 15226916  425 VRDLTggESKGNVWNHCIDDYPPK 448
Cdd:PLN02377 478 LRHVK--PSNNSPWEDCIDKYPVK 499
PLN00415 PLN00415
3-ketoacyl-CoA synthase
 25-446 1.75e-113

3-ketoacyl-CoA synthase


Pssm-ID: 177808  Cd Length: 466  Bit Score: 342.44  E-value: 1.75e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   25 SKQDKDCYILDYQCHKPTDDRMVSTQF-----SGEIIYRNQNLglteyKFLLKAIVSSGIGEQTYAPRLVFEGrEERPSL 99
Cdd:PLN00415  54 TTRSKPVYLVDFSCHQPTDSCKISSETffnmaKGAQLYTEETI-----QFMTRILNRSGLGDDTYSPRCMLTS-PPTPSM 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  100 QDGISEMEEFYVDSIGKLLERNQISPKDIDILVVNVSMLSSTPSLASRIINHYKMRDDVKVFNLTGMGCSASLISVDIVK 179
Cdd:PLN00415 128 YEARHESELVIFGALNSLFKKTGIEPREVGIFIVNCSLFNPNPSLSSMIVNRYKLKTDVKTYNLSGMGCSAGAISVDLAT 207

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  180 NIFKSYANKLALVATSESLSPNWYSGNNRSMILANCLFRSGGCAILLTNKRSLRKKAMFKLKCMVRTHHGAREESYNCCI 259
Cdd:PLN00415 208 NLLKANPNTYAVIVSTENMTLSMYRGNDRSMLVPNCLFRVGGAAVMLSNRSQDRVRSKYELTHIVRTHKGSSDKHYTCAE 287

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  260 QAEDEQGRVGFYLGKNLPKAATRAFVENLKVITPKILPVTELIRFMLKLLIKKIKIRQnpskgstnLPPGTPlkagiNFK 339
Cdd:PLN00415 288 QKEDSKGIVGVALSKELTVVAGDTLKTNLTALGPLVLPLSEKLRFILFLVKSKLFRLK--------VSPYVP-----DFK 354

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  340 TGIEHFCIHTGGKAVIDGIGHSLDLNEYDIEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGAGFKCNS 419
Cdd:PLN00415 355 LCFKHFCIHAGGRALLDAVEKGLGLSEFDLEPSRMTLHRFGNTSSSSLWYELAYVEAKCRVKRGDRVWQLAFGSGFKCNS 434

                        410       420
                 ....*....|....*....|....*...
gi 15226916  420 CVWEVVRDLTGGES-KGNVWNHCIDDYP 446
Cdd:PLN00415 435 IVWRALRTIPANESlVGNPWGDSVHKYP 462
CHS_like cd00831
Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, ...
 31-422 2.94e-113

Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, also called type III PKSs. PKS generate an array of different products, dependent on the nature of the starter molecule. They share a common chemical strategy, after the starter molecule is loaded onto the active site cysteine, a carboxylative condensation reation extends the polyketide chain. Plant-specific PKS are dimeric iterative PKSs, using coenzyme A esters to deliver substrate to the active site, but they differ in the choice of starter molecule and the number of condensation reactions.


Pssm-ID: 238427 [Multi-domain]  Cd Length: 361  Bit Score: 338.04  E-value: 2.94e-113
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  31 CYILDYQCHKPTDDRMVSTQFSGEIIYRNqnLGLTEYKFLLKaivssgIGEQTYAPRLvFEGREERPSLQDGISEMEEFY 110
Cdd:cd00831  19 SELVDFYRRLFSSDHLPELKEKLKRLCAK--TGIETRYLVLP------GGEETYAPRP-EMSPSLDERNDIALEEARELA 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 111 VDSIGKLLERNQISPKDIDILVVNVSMLSSTPSLASRIINHYKMRDDVKVFNLTGMGCSASLISVDIVKNIFKSYANKLA 190
Cdd:cd00831  90 EEAARGALDEAGLRPSDIDHLVVNTSTGNPTPSLDAMLINRLGLRPDVKRYNLGGMGCSAGAIALDLAKDLLEANPGARV 169

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 191 LVATSESLSPnWYSGNN-RSMILANCLFRSGGCAILLTNKRSLRKKamfklkcmvRTHHGAREESYNCCIQaeDEQGRVG 269
Cdd:cd00831 170 LVVSTELCSL-WYRGPDhRSMLVGNALFGDGAAAVLLSNDPRDRRR---------ERPLFELVRAASTLLP--DSEDAMG 237

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 270 FYLGKnlpkaatrafvENLKVITPKilPVTELIRFMLKLLIKKIKIRqnpskgstnlppgtplKAGINFKTGIEHFCIHT 349
Cdd:cd00831 238 WHLGE-----------EGLTFVLSR--DVPRLVEKNLERVLRKLLAR----------------LGIGLFKLAFDHWCVHP 288

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15226916 350 GGKAVIDGIGHSLDLNEYDIEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGAGFKCNSCVW 422
Cdd:cd00831 289 GGRAVLDAVEKALGLSPEDLEASRMVLRRYGNMSSSSVLYVLAYMEAKGRVKRGDRGLLIAFGPGFTCESAVW 361
BH0617 COG3424
Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport and ...
 111-415 5.58e-28

Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442650 [Multi-domain]  Cd Length: 351  Bit Score: 114.08  E-value: 5.58e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 111 VDSIGKLLERNQISPKDIDILVVNvsmlSST----PSLASRIINHYKMRDDVKVFNLTGMGCSASLISVDIVKNIFKSYA 186
Cdd:COG3424  82 EEAARRALDKAGLDPEDIDHLVTV----SCTgfaaPGLDARLINRLGLRPDVRRLPVGGMGCAAGAAGLRRAADFLRADP 157

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 187 NKLALVATSESLS----PNWYSGNNrsmILANCLFRSGGCAILLTNKRslrkkamfklkcmvRTHHGAR-EESYNCCI-Q 260
Cdd:COG3424 158 DAVVLVVCVELCSltfqRDDDSKDN---LVANALFGDGAAAVVVSGDP--------------RPGPGPRiLAFRSYLIpD 220

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 261 AEDEQG-RVG-----FYLGKNLPKAATRAFVENLkvitpkilpvtelirfmlkllikkikirqnpskgstnlppgTPLKA 334
Cdd:COG3424 221 TEDVMGwDVGdtgfrMVLSPEVPDLIAEHLAPAV-----------------------------------------EPLLA 259

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 335 GINFKTG-IEHFCIHTGGKAVIDGIGHSLDLNEYDIEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGA 413
Cdd:COG3424 260 RHGLTIEdIDHWAVHPGGPKVLDAVEEALGLPPEALAHSREVLREYGNMSSATVLFVLERLLEEGAPAPGERGLAMAFGP 339


                ..
gi 15226916 414 GF 415
Cdd:COG3424 340 GF 341
KAS_III cd00830
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty ...
 116-422 5.67e-16

Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP. KASIII initiates this process by specifically using acetyl-CoA over acyl-CoA.


Pssm-ID: 238426 [Multi-domain]  Cd Length: 320  Bit Score: 78.74  E-value: 5.67e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 116 KLLERNQISPKDID-ILVVNVSMLSSTPSLASRIinHYKMR-DDVKVFNLTGmGCSASLISVDIVKNIFKSYANKLALVA 193
Cdd:cd00830  60 KALEDAGIDADDIDlIIVATSTPDYLFPATACLV--QARLGaKNAAAFDINA-ACSGFLYGLSTAAGLIRSGGAKNVLVV 136

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 194 TSESLSP--NWysgNNRSMILancLFRSGGCAILLT---NKRSLrkkamfklkcmVRTHHGAREESYNCCI--------- 259
Cdd:cd00830 137 GAETLSRilDW---TDRSTAV---LFGDGAGAVVLEateEDPGI-----------LDSVLGSDGSGADLLTipaggsrsp 199

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 260 -QAEDEQGRVGFYLGKNLPKAATRafvenlkvITPKIlpVTELIRfmlkllikkikirqnpskgstnlppgtplKAGINf 338
Cdd:cd00830 200 fEDAEGGDPYLVMDGREVFKFAVR--------LMPES--IEEALE-----------------------------KAGLT- 239

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 339 KTGIEHFCIHTGGKAVIDGIGHSLDLneyDIEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGAGFKCN 418
Cdd:cd00830 240 PDDIDWFVPHQANLRIIEAVAKRLGL---PEEKVVVNLDRYGNTSAASIPLALDEAIEEGKLKKGDLVLLLGFGAGLTWG 316


                ....
gi 15226916 419 SCVW 422
Cdd:cd00830 317 AALL 320
FabH COG0332
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ...
 116-423 3.26e-15

3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440101 [Multi-domain]  Cd Length: 323  Bit Score: 76.30  E-value: 3.26e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 116 KLLERNQISPKDID-ILVVNVSMLSSTPSLASRIINHYKMRDdVKVFNLTGmGCSASLISVDIVKNIFKSYANKLALVAT 194
Cdd:COG0332  61 KALEAAGIDPEDIDlIIVATVTPDYLFPSTACLVQHKLGAKN-AAAFDINA-ACSGFVYALSVAAALIRSGQAKNVLVVG 138

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 195 SESLSP--NWysgNNRSmilANCLFRSGGCAILLT---NKRSLrkkamfklkcmVRTHHGAR-EESYNCCIQA------- 261
Cdd:COG0332 139 AETLSRivDW---TDRS---TCVLFGDGAGAVVLEaseEGPGI-----------LGSVLGSDgSGADLLVVPAggsrnpp 201

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 262 -EDEQGRVGFYL-GKNLPKAATRAFVENLKvitpkilpvtELIRfmlkllikkikirqnpskgstnlppgtplKAGINfK 339
Cdd:COG0332 202 sPVDEGDHYLRMdGREVFKFAVRNLPEVIR----------EALE-----------------------------KAGLT-L 241

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 340 TGIEHFCIHTGGKAVIDGIGHSLDlneydIEPAR--MTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGAGFKC 417
Cdd:COG0332 242 DDIDWFIPHQANLRIIEAVAKRLG-----LPEEKvvVNIDRYGNTSAASIPLALDEALREGRIKPGDLVLLAGFGAGLTW 316


                ....*.
gi 15226916 418 NSCVWE 423
Cdd:COG0332 317 GAAVLR 322
ACP_syn_III_C pfam08541
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on ...
 333-423 2.74e-13

3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.41, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.


Pssm-ID: 430060  Cd Length: 90  Bit Score: 65.21  E-value: 2.74e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   333 KAGINfKTGIEHFCIHTGGKAVIDGIGHSLDLNEydiEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFG 412
Cdd:pfam08541   3 KAGLT-PEDIDWFVPHQANLRIIDAVAKRLGLPP---EKVVVNLDEYGNTSAASIPLALDEAVEEGKLKPGDLVLLVGFG 78

                          90
                  ....*....|.
gi 15226916   413 AGFKCNSCVWE 423
Cdd:pfam08541  79 AGLTWGAALLR 89
init_cond_enzymes cd00827
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ...
 111-415 8.80e-10

"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the utlization of CoA substrate primers, as well as the nature of their active site residues.


Pssm-ID: 238423 [Multi-domain]  Cd Length: 324  Bit Score: 60.14  E-value: 8.80e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 111 VDSIGKLLERNQISPKDID-ILVVNVSMLSSTPSLASrIINHYKMRDDVKVFNLTGmGCSASLISVDIVKNIFKSYANKL 189
Cdd:cd00827  53 VEAARRALERAGIDPDDIGlLIVATESPIDKGKSAAT-YLAELLGLTNAEAFDLKQ-ACYGGTAALQLAANLVESGPWRY 130

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 190 ALVATSESLSPNWYSGNNRSMILAnclfrSGGCAILLT---NKRSLRKKAMF--------KLKCMVRTHHGAREESYNCC 258
Cdd:cd00827 131 ALVVASDIASYLLDEGSALEPTLG-----DGAAAMLVSrnpGILAAGIVSTHstsdpgydFSPYPVMDGGYPKPCKLAYA 205

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 259 IQAEDEQGRVGFYL--GKNLPKAATRAFVEnlkvitpkilpvtelirfmlkllikkikirqnpskgstnlppgtplkagI 336
Cdd:cd00827 206 IRLTAEPAGRAVFEaaHKLIAKVVRKALDR-------------------------------------------------A 236

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916 337 NFKTGIEHFCIHTG-GKAVIDGIGHSLDLNEYDIEPARMT-LHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGAG 414
Cdd:cd00827 237 GLSEDIDYFVPHQPnGKKILEAVAKKLGGPPEKASQTRWIlLRRVGNMYAASILLGLASLLESGKLKAGDRVLLFSYGSG 316


                .
gi 15226916 415 F 415
Cdd:cd00827 317 F 317
PRK09352 PRK09352
beta-ketoacyl-ACP synthase 3;
355-415 5.58e-08

beta-ketoacyl-ACP synthase 3;


Pssm-ID: 236475 [Multi-domain]  Cd Length: 319  Bit Score: 54.31  E-value: 5.58e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15226916  355 IDGIGHSLDLneyDIEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGAGF 415
Cdd:PRK09352 252 IDATAKKLGL---PMEKVVVTVDKYGNTSAASIPLALDEAVRDGRIKRGDLVLLEGFGGGL 309
PLN03169 PLN03169
chalcone synthase family protein; Provisional
 335-414 1.60e-07

chalcone synthase family protein; Provisional


Pssm-ID: 215612 [Multi-domain]  Cd Length: 391  Bit Score: 53.16  E-value: 1.60e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  335 GINFKTG----------IEHFC--------------------IHTGGKAVIDGIGHSLDLNEYDIEPARMTLHRFGNTSA 384
Cdd:PLN03169 266 GINFKLGrelpqkiednIEGFCkklmkkaglvekdyndlfwaVHPGGPAILNRLEKKLKLAPEKLECSRRALMDYGNVSS 345

                         90       100       110
                 ....*....|....*....|....*....|...
gi 15226916  385 SSLWYVLAYM-EAKKRLKRGDRVF--MISFGAG 414
Cdd:PLN03169 346 NTIVYVLEYMrEELKKKGEEDEEWglILAFGPG 378
PRK05963 PRK05963
beta-ketoacyl-ACP synthase III;
342-424 1.11e-06

beta-ketoacyl-ACP synthase III;


Pssm-ID: 180328 [Multi-domain]  Cd Length: 326  Bit Score: 50.49  E-value: 1.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  342 IEHFCIHTGGKAVIDGIGHSLDlneydIEPARM--TLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGAGFKCNS 419
Cdd:PRK05963 247 IDRFFPHQANARIVDKVCETIG-----IPRAKAasTLETYGNSSAATIPLSLSLANLEQPLREGERLLFAAAGAGMTGGA 321


                 ....*
gi 15226916  420 CVWEV 424
Cdd:PRK05963 322 VVMRV 326
Chal_sti_synt_C pfam02797
Chalcone and stilbene synthases, C-terminal domain; This domain of chalcone synthase is ...
 333-414 3.28e-06

Chalcone and stilbene synthases, C-terminal domain; This domain of chalcone synthase is reported to be structurally similar to domains in thiolase and beta-ketoacyl synthase. The differences in activity are accounted for by differences in the N-terminal domain.


Pssm-ID: 397089  Cd Length: 151  Bit Score: 46.68  E-value: 3.28e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916   333 KAGINFKTG----------IEHFC------------------IHTGGKAVIDGIGHSLDLNEYDIEPARMTLHRFGNTSA 384
Cdd:pfam02797  23 EEGLTFHLGrdvpqkieenIEEFLkkafeplgisewnslfwiVHPGGPAILDRVETKLGLEPEKLEASRRALMDYGNVSS 102

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 15226916   385 SSLWYVLAYM---EAKKRLKRG----DRVFMISFGAG 414
Cdd:pfam02797 103 ATVLFILDEMrkkSLKKGLATTgeglDWGVLLAFGPG 139
PRK12879 PRK12879
3-oxoacyl-(acyl carrier protein) synthase III; Reviewed
 333-415 1.81e-03

3-oxoacyl-(acyl carrier protein) synthase III; Reviewed


Pssm-ID: 237245 [Multi-domain]  Cd Length: 325  Bit Score: 40.23  E-value: 1.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226916  333 KAGINfKTGIEHFCIHTGGKAVIDGIGHSLDLneyDIEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFG 412
Cdd:PRK12879 237 KAGLT-KDDIDWVIPHQANLRIIESLCEKLGI---PMEKTLVSVEYYGNTSAATIPLALDLALEQGKIKPGDTLLLYGFG 312


                 ...
gi 15226916  413 AGF 415
Cdd:PRK12879 313 AGL 315
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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