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Conserved domains on  [gi|30685372|ref|NP_180825|]
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receptor like protein 22 [Arabidopsis thaliana]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 1000136)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN00113 super family cl33413
leucine-rich repeat receptor-like protein kinase; Provisional
 1-517 5.30e-59

leucine-rich repeat receptor-like protein kinase; Provisional


The actual alignment was detected with superfamily member PLN00113:

Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 212.40  E-value: 5.30e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372    1 MPFLSYLDLSENHLTGSF--EISNSSSKLENLNLGNNHFETEIidPVLRLVNLRYLSLS--FLNTSHPIDLSIFSplqSL 76
Cdd:PLN00113  92 LPYIQTINLSNNQLSGPIpdDIFTTSSSLRYLNLSNNNFTGSI--PRGSIPNLETLDLSnnMLSGEIPNDIGSFS---SL 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372   77 THLDLHGNSLTlTSVYSDIDFPKNMEILLL-SGCNISEFPRFLKSLKKLWYLDLSSNRIKGNVPDWIWSLPLLVSLDLSN 155
Cdd:PLN00113 167 KVLDLGGNVLV-GKIPNSLTNLTSLEFLTLaSNQLVGQIPRELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVY 245

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  156 NSFTgfnGSLDHVLAN-SSVQVLDIALNSFKGSFPNPPVS---IINLSAWNNSFTGDIPLSVCNRTSLDVLDLSYNNFTG 231
Cdd:PLN00113 246 NNLT---GPIPSSLGNlKNLQYLFLYQNKLSGPIPPSIFSlqkLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTG 322

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  232 SIPPCMGN---FTIVNLRKNKLEGNIPDEFYSGALTQTLDVGYNQLTGELPRSLLNCSFIRFLSVDHNRINDSFPLWLKA 308
Cdd:PLN00113 323 KIPVALTSlprLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGA 402

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  309 LPNLKVLTLRSNSFHGPMSPpddqsslAFPKLQI---LEISHNRFTGSLPTNyfaNWSVKSLKMYDEER-LYMGD----Y 380
Cdd:PLN00113 403 CRSLRRVRLQDNSFSGELPS-------EFTKLPLvyfLDISNNNLQGRINSR---KWDMPSLQMLSLARnKFFGGlpdsF 472

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  381 SSDRFVYEDTLDLQYKGLYMEQGKVLTFYSAIDFSGNKLEGEIPESIGLLKTLIALNLSNNSFTGHIPMSFANVTELESL 460
Cdd:PLN00113 473 GSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQL 552

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 30685372  461 DLSGNKLSGEIPQELGRLSYLAYIDVSDNQLTGKIPQGTQIIGQPKSSFEGNSGLCG 517
Cdd:PLN00113 553 DLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 1-517 5.30e-59

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 212.40  E-value: 5.30e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372    1 MPFLSYLDLSENHLTGSF--EISNSSSKLENLNLGNNHFETEIidPVLRLVNLRYLSLS--FLNTSHPIDLSIFSplqSL 76
Cdd:PLN00113  92 LPYIQTINLSNNQLSGPIpdDIFTTSSSLRYLNLSNNNFTGSI--PRGSIPNLETLDLSnnMLSGEIPNDIGSFS---SL 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372   77 THLDLHGNSLTlTSVYSDIDFPKNMEILLL-SGCNISEFPRFLKSLKKLWYLDLSSNRIKGNVPDWIWSLPLLVSLDLSN 155
Cdd:PLN00113 167 KVLDLGGNVLV-GKIPNSLTNLTSLEFLTLaSNQLVGQIPRELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVY 245

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  156 NSFTgfnGSLDHVLAN-SSVQVLDIALNSFKGSFPNPPVS---IINLSAWNNSFTGDIPLSVCNRTSLDVLDLSYNNFTG 231
Cdd:PLN00113 246 NNLT---GPIPSSLGNlKNLQYLFLYQNKLSGPIPPSIFSlqkLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTG 322

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  232 SIPPCMGN---FTIVNLRKNKLEGNIPDEFYSGALTQTLDVGYNQLTGELPRSLLNCSFIRFLSVDHNRINDSFPLWLKA 308
Cdd:PLN00113 323 KIPVALTSlprLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGA 402

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  309 LPNLKVLTLRSNSFHGPMSPpddqsslAFPKLQI---LEISHNRFTGSLPTNyfaNWSVKSLKMYDEER-LYMGD----Y 380
Cdd:PLN00113 403 CRSLRRVRLQDNSFSGELPS-------EFTKLPLvyfLDISNNNLQGRINSR---KWDMPSLQMLSLARnKFFGGlpdsF 472

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  381 SSDRFVYEDTLDLQYKGLYMEQGKVLTFYSAIDFSGNKLEGEIPESIGLLKTLIALNLSNNSFTGHIPMSFANVTELESL 460
Cdd:PLN00113 473 GSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQL 552

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 30685372  461 DLSGNKLSGEIPQELGRLSYLAYIDVSDNQLTGKIPQGTQIIGQPKSSFEGNSGLCG 517
Cdd:PLN00113 553 DLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
4-301 1.25e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 88.45  E-value: 1.25e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372   4 LSYLDLSENHLTGSFEISNSSSKLENLNLGNNHFETEIIDPVLRLVNLRYLSLSFLNTshpidlsiFSPLQSLTHLDLHG 83
Cdd:COG4886  51 LLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEE--------LSNLTNLESLDLSG 122

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  84 NSltLTSVYSDIDFPKNMEILLLSGCNISEFPRFLKSLKKLWYLDLSSNRIKgNVPDWIWSLPLLVSLDLSNNSFTgfng 163
Cdd:COG4886 123 NQ--LTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQIT---- 195

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372 164 SLDHVLAN-SSVQVLDIA---LNSFKGSFPNPPvSIINLSAWNNSFTgDIPlSVCNRTSLDVLDLSYNNFTgSIPPC--M 237
Cdd:COG4886 196 DLPEPLGNlTNLEELDLSgnqLTDLPEPLANLT-NLETLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQLT-DLPPLanL 271

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 30685372 238 GNFTIVNLRKNKLEGNIPDEFYSGALTQTLDVGYNQLTGELPRSLLNCSFIRFLSVDHNRINDS 301
Cdd:COG4886 272 TNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLV 335
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 4-230 9.17e-07

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 51.20  E-value: 9.17e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372   4 LSYLDLSENHLTGSFEISNSSSKLENLNLGNNhfETEIIDPVLRLV--------NLRYLSLSflNTSHPIDLS-IFSPLQ 74
Cdd:cd00116  30 LEGNTLGEEAAKALASALRPQPSLKELCLSLN--ETGRIPRGLQSLlqgltkgcGLQELDLS--DNALGPDGCgVLESLL 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  75 ---SLTHLDLHGNSL----TLTSVYSDIDFPKNMEILLLSGCNISEFPRF-----LKSLKKLWYLDLSSNRIKGnvpDWI 142
Cdd:cd00116 106 rssSLQELKLNNNGLgdrgLRLLAKGLKDLPPALEKLVLGRNRLEGASCEalakaLRANRDLKELNLANNGIGD---AGI 182

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372 143 WSL-------PLLVSLDLSNNSFTGFNGS-LDHVLA-NSSVQVLDIALNS--------FKGSFPNPPVSIINLSAWNNSF 205
Cdd:cd00116 183 RALaeglkanCNLEVLDLNNNGLTDEGASaLAETLAsLKSLEVLNLGDNNltdagaaaLASALLSPNISLLTLSLSCNDI 262

                       250       260
                ....*....|....*....|....*....
gi 30685372 206 TGDIPLSVC----NRTSLDVLDLSYNNFT 230
Cdd:cd00116 263 TDDGAKDLAevlaEKESLLELDLRGNKFG 291
LRR_8 pfam13855
Leucine rich repeat;
100-158 8.50e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 43.28  E-value: 8.50e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372   100 NMEILLLSGCNISEF-PRFLKSLKKLWYLDLSSNRIKGNVPDWIWSLPLLVSLDLSNNSF 158
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 1-517 5.30e-59

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 212.40  E-value: 5.30e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372    1 MPFLSYLDLSENHLTGSF--EISNSSSKLENLNLGNNHFETEIidPVLRLVNLRYLSLS--FLNTSHPIDLSIFSplqSL 76
Cdd:PLN00113  92 LPYIQTINLSNNQLSGPIpdDIFTTSSSLRYLNLSNNNFTGSI--PRGSIPNLETLDLSnnMLSGEIPNDIGSFS---SL 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372   77 THLDLHGNSLTlTSVYSDIDFPKNMEILLL-SGCNISEFPRFLKSLKKLWYLDLSSNRIKGNVPDWIWSLPLLVSLDLSN 155
Cdd:PLN00113 167 KVLDLGGNVLV-GKIPNSLTNLTSLEFLTLaSNQLVGQIPRELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVY 245

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  156 NSFTgfnGSLDHVLAN-SSVQVLDIALNSFKGSFPNPPVS---IINLSAWNNSFTGDIPLSVCNRTSLDVLDLSYNNFTG 231
Cdd:PLN00113 246 NNLT---GPIPSSLGNlKNLQYLFLYQNKLSGPIPPSIFSlqkLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTG 322

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  232 SIPPCMGN---FTIVNLRKNKLEGNIPDEFYSGALTQTLDVGYNQLTGELPRSLLNCSFIRFLSVDHNRINDSFPLWLKA 308
Cdd:PLN00113 323 KIPVALTSlprLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGA 402

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  309 LPNLKVLTLRSNSFHGPMSPpddqsslAFPKLQI---LEISHNRFTGSLPTNyfaNWSVKSLKMYDEER-LYMGD----Y 380
Cdd:PLN00113 403 CRSLRRVRLQDNSFSGELPS-------EFTKLPLvyfLDISNNNLQGRINSR---KWDMPSLQMLSLARnKFFGGlpdsF 472

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  381 SSDRFVYEDTLDLQYKGLYMEQGKVLTFYSAIDFSGNKLEGEIPESIGLLKTLIALNLSNNSFTGHIPMSFANVTELESL 460
Cdd:PLN00113 473 GSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQL 552

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 30685372  461 DLSGNKLSGEIPQELGRLSYLAYIDVSDNQLTGKIPQGTQIIGQPKSSFEGNSGLCG 517
Cdd:PLN00113 553 DLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 172-498 1.25e-35

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 143.06  E-value: 1.25e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  172 SSVQVLDIALNSFKGS-----FPNPPVSIINLSawNNSFTGDIPLSV-CNRTSLDVLDLSYNNFTGSIPP-CMGNFTIVN 244
Cdd:PLN00113  69 SRVVSIDLSGKNISGKissaiFRLPYIQTINLS--NNQLSGPIPDDIfTTSSSLRYLNLSNNNFTGSIPRgSIPNLETLD 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  245 LRKNKLEGNIPDEFYSGALTQTLDVGYNQLTGELPRSLLNCSFIRFLSVDHNRINDSFPLWLKALPNLKVLTLRSNSFHG 324
Cdd:PLN00113 147 LSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSG 226

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  325 PMspPDDQSSLAfpKLQILEISHNRFTGSLPTNyfanwsvkslkmydeerlyMGDYSsdrfvyedtlDLQYKGLYmeQGK 404
Cdd:PLN00113 227 EI--PYEIGGLT--SLNHLDLVYNNLTGPIPSS-------------------LGNLK----------NLQYLFLY--QNK 271

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  405 V----------LTFYSAIDFSGNKLEGEIPESIGLLKTLIALNLSNNSFTGHIPMSFANVTELESLDLSGNKLSGEIPQE 474
Cdd:PLN00113 272 LsgpippsifsLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKN 351

                        330       340
                 ....*....|....*....|....
gi 30685372  475 LGRLSYLAYIDVSDNQLTGKIPQG 498
Cdd:PLN00113 352 LGKHNNLTVLDLSTNNLTGEIPEG 375
PLN03150 PLN03150
hypothetical protein; Provisional
 408-524 1.68e-21

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 98.73  E-value: 1.68e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  408 FYSAIDFSGNKLEGEIPESIGLLKTLIALNLSNNSFTGHIPMSFANVTELESLDLSGNKLSGEIPQELGRLSYLAYIDVS 487
Cdd:PLN03150 419 FIDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLN 498

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 30685372  488 DNQLTGKIPQ--GTQIIGQPKSSFEGNSGLCGLPLEESC 524
Cdd:PLN03150 499 GNSLSGRVPAalGGRLLHRASFNFTDNAGLCGIPGLRAC 537
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
4-301 1.25e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 88.45  E-value: 1.25e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372   4 LSYLDLSENHLTGSFEISNSSSKLENLNLGNNHFETEIIDPVLRLVNLRYLSLSFLNTshpidlsiFSPLQSLTHLDLHG 83
Cdd:COG4886  51 LLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEE--------LSNLTNLESLDLSG 122

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  84 NSltLTSVYSDIDFPKNMEILLLSGCNISEFPRFLKSLKKLWYLDLSSNRIKgNVPDWIWSLPLLVSLDLSNNSFTgfng 163
Cdd:COG4886 123 NQ--LTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQIT---- 195

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372 164 SLDHVLAN-SSVQVLDIA---LNSFKGSFPNPPvSIINLSAWNNSFTgDIPlSVCNRTSLDVLDLSYNNFTgSIPPC--M 237
Cdd:COG4886 196 DLPEPLGNlTNLEELDLSgnqLTDLPEPLANLT-NLETLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQLT-DLPPLanL 271

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 30685372 238 GNFTIVNLRKNKLEGNIPDEFYSGALTQTLDVGYNQLTGELPRSLLNCSFIRFLSVDHNRINDS 301
Cdd:COG4886 272 TNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLV 335
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
4-352 2.69e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 78.05  E-value: 2.69e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372   4 LSYLDLSENHLTGSFEISNSSSKLENLNLGNNHFETEIIDPVLRLVNLRYLSLSFLNTSHPIDLSIFSPLQSLTHLDLHG 83
Cdd:COG4886   1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  84 NSLTLTSVYSDIDFPKNMEILLLSGCNisefprFLKSLKKLWYLDLSSNRIKgNVPDWIWSLPLLVSLDLSNNSFTgfng 163
Cdd:COG4886  81 LLSLLLLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLT---- 149

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372 164 sldhvlanssvqvldiALNSFKGSFPNppvsIINLSAWNNSFTgDIPLSVCNRTSLDVLDLSYNNFTgSIPPCMGNFTiv 243
Cdd:COG4886 150 ----------------DLPEPLGNLTN----LKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQIT-DLPEPLGNLT-- 205

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372 244 NLrknklegnipdefysgaltQTLDVGYNQLTgELPRSLLNCSFIRFLSVDHNRINDsFPlWLKALPNLKVLTLRSNSFH 323
Cdd:COG4886 206 NL-------------------EELDLSGNQLT-DLPEPLANLTNLETLDLSNNQLTD-LP-ELGNLTNLEELDLSNNQLT 263

                       330       340
                ....*....|....*....|....*....
gi 30685372 324 gpmsppDDQSSLAFPKLQILEISHNRFTG 352
Cdd:COG4886 264 ------DLPPLANLTNLKTLDLSNNQLTD 286
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
147-493 6.96e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 70.73  E-value: 6.96e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372 147 LLVSLDLSNNSFTGFNGSLDHVLANSSVQVLDIALNSFKGSFPNPPVSIINLSAWNNSFTGDIPLSVCNRTSLDVLDLSY 226
Cdd:COG4886   5 LLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSL 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372 227 NNFTGSIPPCMGNFTIVNLRKNKLEGNIPDefysgalTQTLDVGYNQLTgELPRSLLNCSFIRFLSVDHNRINDsFPLWL 306
Cdd:COG4886  85 LLLGLTDLGDLTNLTELDLSGNEELSNLTN-------LESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLTD-LPEPL 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372 307 KALPNLKVLTLRSNSFHGpmsppDDQSSLAFPKLQILEISHNRFTgSLPTNyFANWsvKSLKmydeerlymgdyssdrfv 386
Cdd:COG4886 156 GNLTNLKSLDLSNNQLTD-----LPEELGNLTNLKELDLSNNQIT-DLPEP-LGNL--TNLE------------------ 208

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372 387 yedTLDLqykglymeqgkvltfysaidfSGNKLEgEIPESIGLLKTLIALNLSNNSFTgHIPmSFANVTELESLDLSGNK 466
Cdd:COG4886 209 ---ELDL---------------------SGNQLT-DLPEPLANLTNLETLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQ 261

                       330       340
                ....*....|....*....|....*..
gi 30685372 467 LSgEIPqELGRLSYLAYIDVSDNQLTG 493
Cdd:COG4886 262 LT-DLP-PLANLTNLKTLDLSNNQLTD 286
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
118-496 2.74e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 65.73  E-value: 2.74e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372 118 LKSLKKLWYLDLSSNRIKGNVPDWIWSLPLLVSLDLSNNSFTGFNGSLDHVLANSSVQVLDIALNSFKGSFPNPPVSIIN 197
Cdd:COG4886   1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372 198 LSAWNNSFTGDIPlsvcNRTSLDVLDLSYNNFTGSIPpcmgNFTIVNLRKNKLEgNIPDEFYSGALTQTLDVGYNQLTgE 277
Cdd:COG4886  81 LLSLLLLGLTDLG----DLTNLTELDLSGNEELSNLT----NLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLT-D 150

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372 278 LPRSLLNCSFIRFLSVDHNRINDsFPLWLKALPNLKVLTLRSNSFHgpmsppDDQSSLA-FPKLQILEISHNRFTgSLPT 356
Cdd:COG4886 151 LPEPLGNLTNLKSLDLSNNQLTD-LPEELGNLTNLKELDLSNNQIT------DLPEPLGnLTNLEELDLSGNQLT-DLPE 222

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372 357 NyFANWsvKSLKmydeerlymgdyssdrfvyedTLDLqykglymeqgkvltfysaidfSGNKLEgEIPEsIGLLKTLIAL 436
Cdd:COG4886 223 P-LANL--TNLE---------------------TLDL---------------------SNNQLT-DLPE-LGNLTNLEEL 255

                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372 437 NLSNNSFTgHIPMSfANVTELESLDLSGNKLSGEIPQELGRLSYLAYIDVSDNQLTGKIP 496
Cdd:COG4886 256 DLSNNQLT-DLPPL-ANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLEL 313
PLN03150 PLN03150
hypothetical protein; Provisional
 158-255 3.59e-11

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 65.99  E-value: 3.59e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  158 FTGFNGSLDHVLANSSVQVLDIALNSFKGSFPNPPVSI-----INLSawNNSFTGDIPLSVCNRTSLDVLDLSYNNFTGS 232
Cdd:PLN03150 404 WSGADCQFDSTKGKWFIDGLGLDNQGLRGFIPNDISKLrhlqsINLS--GNSIRGNIPPSLGSITSLEVLDLSYNSFNGS 481

                         90       100
                 ....*....|....*....|....*.
gi 30685372  233 IPPCMGNFT---IVNLRKNKLEGNIP 255
Cdd:PLN03150 482 IPESLGQLTslrILNLNGNSLSGRVP 507
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
1-211 2.25e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 63.03  E-value: 2.25e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372   1 MPFLSYLDLSENHLTG-SFEISNsSSKLENLNLGNNHFeTEIIDPVLRLVNLRYLSLSFlNTSHPIDLSIfSPLQSLTHL 79
Cdd:COG4886 158 LTNLKSLDLSNNQLTDlPEELGN-LTNLKELDLSNNQI-TDLPEPLGNLTNLEELDLSG-NQLTDLPEPL-ANLTNLETL 233

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  80 DLHGNSLTltsvysdiDFP-----KNMEILLLSGCNISEFPrFLKSLKKLWYLDLSSNRIKGNVPDWIWSLPLLVSLDLS 154
Cdd:COG4886 234 DLSNNQLT--------DLPelgnlTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLL 304

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 30685372 155 NNSFTGFNGSLDHVLANSSVQVLDIALNSFKGSFPNPPVSIINLSAWNNSFTGDIPL 211
Cdd:COG4886 305 LLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSL 361
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 1-218 1.83e-09

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 60.63  E-value: 1.83e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372    1 MPFLSYLDLSENHLTGSFEISNSSSKLENLNLGNNHFETEIidpvlrlvnlrylslsflntshPIDLSIFSplqSLTHLD 80
Cdd:PLN00113 451 MPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSGAV----------------------PRKLGSLS---ELMQLK 505

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372   81 LHGNSLTltsvysdidfpknmeilllsgcniSEFPRFLKSLKKLWYLDLSSNRIKGNVPDWIWSLPLLVSLDLSNNSFTG 160
Cdd:PLN00113 506 LSENKLS------------------------GEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSG 561

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  161 -FNGSLDHVlaNSSVQVlDIALNSFKGSFPNPPVSI-INLSAwnnsFTGDIPLSVCNRTS 218
Cdd:PLN00113 562 eIPKNLGNV--ESLVQV-NISHNHLHGSLPSTGAFLaINASA----VAGNIDLCGGDTTS 614
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
86-322 1.26e-08

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 57.78  E-value: 1.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372   86 LTLTSVYSDIdfPKNMEILLLSGCNISEFPRFLK-SLKKLWYLDLSSNRIKGNVPDWIWSLPL---------------LV 149
Cdd:PRK15370 188 LGLTTIPACI--PEQITTLILDNNELKSLPENLQgNIKTLYANSNQLTSIPATLPDTIQEMELsinritelperlpsaLQ 265

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  150 SLDLSNNSFTGFNGSLDHVLanssvQVLDIALNSFKGSFPNPPVSIINLSAWNNSFTGdIPLSVcnRTSLDVLDLSYNNF 229
Cdd:PRK15370 266 SLDLFHNKISCLPENLPEEL-----RYLSVYDNSIRTLPAHLPSGITHLNVQSNSLTA-LPETL--PPGLKTLEAGENAL 337

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  230 T---GSIPPCMGNFTIVNLRKNKLEGNIPDEFysgaltQTLDVGYNQLTgELPRSLlnCSFIRFLSVDHN---RINDSFP 303
Cdd:PRK15370 338 TslpASLPPELQVLDVSKNQITVLPETLPPTI------TTLDVSRNALT-NLPENL--PAALQIMQASRNnlvRLPESLP 408

                        250
                 ....*....|....*....
gi 30685372  304 LWLKALPNLKVLTLRSNSF 322
Cdd:PRK15370 409 HFRGEGPQPTRIIVEYNPF 427
PLN03150 PLN03150
hypothetical protein; Provisional
 114-189 9.17e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 51.74  E-value: 9.17e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30685372  114 FPRFLKSLKKLWYLDLSSNRIKGNVPDWIWSLPLLVSLDLSNNSftgFNGSLDHVLAN-SSVQVLDIALNSFKGSFP 189
Cdd:PLN03150 434 IPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNS---FNGSIPESLGQlTSLRILNLNGNSLSGRVP 507
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 4-230 9.17e-07

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 51.20  E-value: 9.17e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372   4 LSYLDLSENHLTGSFEISNSSSKLENLNLGNNhfETEIIDPVLRLV--------NLRYLSLSflNTSHPIDLS-IFSPLQ 74
Cdd:cd00116  30 LEGNTLGEEAAKALASALRPQPSLKELCLSLN--ETGRIPRGLQSLlqgltkgcGLQELDLS--DNALGPDGCgVLESLL 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  75 ---SLTHLDLHGNSL----TLTSVYSDIDFPKNMEILLLSGCNISEFPRF-----LKSLKKLWYLDLSSNRIKGnvpDWI 142
Cdd:cd00116 106 rssSLQELKLNNNGLgdrgLRLLAKGLKDLPPALEKLVLGRNRLEGASCEalakaLRANRDLKELNLANNGIGD---AGI 182

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372 143 WSL-------PLLVSLDLSNNSFTGFNGS-LDHVLA-NSSVQVLDIALNS--------FKGSFPNPPVSIINLSAWNNSF 205
Cdd:cd00116 183 RALaeglkanCNLEVLDLNNNGLTDEGASaLAETLAsLKSLEVLNLGDNNltdagaaaLASALLSPNISLLTLSLSCNDI 262

                       250       260
                ....*....|....*....|....*....
gi 30685372 206 TGDIPLSVC----NRTSLDVLDLSYNNFT 230
Cdd:cd00116 263 TDDGAKDLAevlaEKESLLELDLRGNKFG 291
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 433-499 3.08e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 50.23  E-value: 3.08e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 30685372  433 LIALNLSNNSFTGHIPMSFANVTELESLDLSGNKLSGEIPQELGRLSY-LAYIDVSDNQLTGKIPQGT 499
Cdd:PLN00113  71 VVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDIFTTSSsLRYLNLSNNNFTGSIPRGS 138
LRR_8 pfam13855
Leucine rich repeat;
100-158 8.50e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 43.28  E-value: 8.50e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372   100 NMEILLLSGCNISEF-PRFLKSLKKLWYLDLSSNRIKGNVPDWIWSLPLLVSLDLSNNSF 158
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 219-310 9.24e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 48.66  E-value: 9.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  219 LDVLDLSYNNFTGSIP---PCMGNFTIVNLRKNKLEGNIPDEFYSGALTQTLDVGYNQLTGELPRSLLNCSFIRFLSVDH 295
Cdd:PLN03150 420 IDGLGLDNQGLRGFIPndiSKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNG 499

                         90
                 ....*....|....*
gi 30685372  296 NRINDSFPLWLKALP 310
Cdd:PLN03150 500 NSLSGRVPAALGGRL 514
PLN03150 PLN03150
hypothetical protein; Provisional
 127-238 3.39e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 46.73  E-value: 3.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  127 LDLSSNRIKGNVPDWIWSLPLLVSLDLSNNSFTG-FNGSLDHVlanSSVQVLDIALNSFKGSfpnppvsiinlsawnnsf 205
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGnIPPSLGSI---TSLEVLDLSYNSFNGS------------------ 481

                         90       100       110
                 ....*....|....*....|....*....|...
gi 30685372  206 tgdIPLSVCNRTSLDVLDLSYNNFTGSIPPCMG 238
Cdd:PLN03150 482 ---IPESLGQLTSLRILNLNGNSLSGRVPAALG 511
PLN03150 PLN03150
hypothetical protein; Provisional
 243-324 5.50e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 45.96  E-value: 5.50e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  243 VNLRKNKLEGNIPDEFYSGALTQTLDVGYNQLTGELPRSLLNCSFIRFLSVDHNRINDSFPLWLKALPNLKVLTLRSNSF 322
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502


                 ..
gi 30685372  323 HG 324
Cdd:PLN03150 503 SG 504
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 453-497 5.95e-05

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 45.99  E-value: 5.95e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 30685372  453 NVTELESLDLSGNKLSGEIPQELGRLSYLAYIDVSDNQLTGKIPQ 497
Cdd:PLN00113  67 NSSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPD 111
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 4-159 2.66e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 42.47  E-value: 2.66e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372   4 LSYLDLSENHLTgSFEISNSSSKLENLNLGNNHFETeiIDPVLRLVNLRYLSLSFlNTshpidLSIFSPLQSLTHL-DLH 82
Cdd:cd21340  26 LKVLYLYDNKIT-KIENLEFLTNLTHLYLQNNQIEK--IENLENLVNLKKLYLGG-NR-----ISVVEGLENLTNLeELH 96

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  83 --------GNSLTLtSVYSDIDFPKNMEILLLSGCNISEfPRFLKSLKKLWYLDLSSNRIK--GNVPDWIWSLPLLVSLD 152
Cdd:cd21340  97 ienqrlppGEKLTF-DPRSLAALSNSLRVLNISGNNIDS-LEPLAPLRNLEQLDASNNQISdlEELLDLLSSWPSLRELD 174


                ....*..
gi 30685372 153 LSNNSFT 159
Cdd:cd21340 175 LTGNPVC 181
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 424-489 3.53e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 42.08  E-value: 3.53e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 30685372 424 PESI-GLLKTLIALNLSNNSFTghIPMSFANVTELESLDLSGNKLS--GEIPQELGRLSYLAYIDVSDN 489
Cdd:cd21340 112 PRSLaALSNSLRVLNISGNNID--SLEPLAPLRNLEQLDASNNQISdlEELLDLLSSWPSLRELDLTGN 178
LRR_8 pfam13855
Leucine rich repeat;
436-491 8.04e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.89  E-value: 8.04e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 30685372   436 LNLSNNSFTGHIPMSFANVTELESLDLSGNKLSGEIPQELGRLSYLAYIDVSDNQL 491
Cdd:pfam13855   6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 4-182 8.65e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 40.92  E-value: 8.65e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372   4 LSYLDLSENHLTgSFEISNSSSKLENLNLGNNHFETeiIDPVLRLVNLRYLSLSFLNTSHpidLSIFSPLQSLTHLDLHG 83
Cdd:cd21340   4 ITHLYLNDKNIT-KIDNLSLCKNLKVLYLYDNKITK--IENLEFLTNLTHLYLQNNQIEK---IENLENLVNLKKLYLGG 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30685372  84 NSLtltSVYSDIDFPKNMEILLLSGCNISE-----F-PRFLKSLKK-LWYLDLSSNRIkgNVPDWIWSLPLLVSLDLSNN 156
Cdd:cd21340  78 NRI---SVVEGLENLTNLEELHIENQRLPPgekltFdPRSLAALSNsLRVLNISGNNI--DSLEPLAPLRNLEQLDASNN 152

                       170       180
                ....*....|....*....|....*.
gi 30685372 157 SFTGFNGSLDHVLANSSVQVLDIALN 182
Cdd:cd21340 153 QISDLEELLDLLSSWPSLRELDLTGN 178
PLN03150 PLN03150
hypothetical protein; Provisional
 287-355 3.22e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 40.57  E-value: 3.22e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 30685372  287 FIRFLSVDHNRINDSFPLWLKALPNLKVLTLRSNSFHGPMSPpddqSSLAFPKLQILEISHNRFTGSLP 355
Cdd:PLN03150 419 FIDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPP----SLGSITSLEVLDLSYNSFNGSIP 483
LRR_8 pfam13855
Leucine rich repeat;
412-467 5.49e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.58  E-value: 5.49e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 30685372   412 IDFSGNKLEGEIPESIGLLKTLIALNLSNNSFTGHIPMSFANVTELESLDLSGNKL 467
Cdd:pfam13855   6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 93-160 9.58e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 39.03  E-value: 9.58e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 30685372   93 SDIDFPKNMEILLLSGCNI-SEFPRFLKSLKKLWYLDLSSNRIKGNVPDWIWSLPLLVSLDLSNNSFTG 160
Cdd:PLN03150 436 NDISKLRHLQSINLSGNSIrGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSG 504
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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