|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02369 |
PLN02369 |
ribose-phosphate pyrophosphokinase |
51-352 |
0e+00 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 215209 [Multi-domain] Cd Length: 302 Bit Score: 630.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 51 PALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNENLMELLIMVDACRRASAKKVTAVIPYF 130
Cdd:PLN02369 1 PALSQEIACYLGLELGKITIKRFADGEIYVQLQESVRGCDVFLVQPTCPPANENLMELLIMIDACRRASAKRITAVIPYF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 131 GYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSIPSEDLVVVSPDV 210
Cdd:PLN02369 81 GYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKTISSPDLVVVSPDV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 211 GGVARARAFAKKLSDAPLAIVDKRRSGHNVAEVMNLIGDVRGKVAIMVDDMIDTAGTIVKGAALLHQEGAREVYACCTHA 290
Cdd:PLN02369 161 GGVARARAFAKKLSDAPLAIVDKRRQGHNVAEVMNLIGDVKGKVAIMVDDMIDTAGTITKGAALLHQEGAREVYACATHA 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15226977 291 VFSPPAIERLSGGLLQEVIVTNTLPVAEKNYFPQLTILSVANLLGETIWRVHDDSSVSSIFL 352
Cdd:PLN02369 241 VFSPPAIERLSSGLFQEVIVTNTIPVSEKNYFPQLTVLSVANLLGETIWRVHDDCSVSSIFD 302
|
|
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
39-351 |
0e+00 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 541.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 39 NTRLKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNENLMELLIMVDACRRA 118
Cdd:COG0462 1 MKDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 119 SAKKVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSI 198
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSKDL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 199 psEDLVVVSPDVGGVARARAFAKKLsDAPLAIVDKRRSGHNVAEVMNLIGDVRGKVAIMVDDMIDTAGTIVKGAALLHQE 278
Cdd:COG0462 161 --EDLVVVSPDVGGVKRARAFAKRL-GAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEA 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15226977 279 GAREVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLPVAEKNYFPQLTILSVANLLGETIWRVHDDSSVSSIF 351
Cdd:COG0462 238 GAKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEEKRCDKIKVLSVAPLLAEAIRRIHEGESVSSLF 310
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
42-351 |
6.52e-154 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 434.78 E-value: 6.52e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 42 LKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLV-QPTCTPTNENLMELLIMVDACRRASA 120
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 121 KKVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLasKSIPS 200
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKSREPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYL--KKKIL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 201 EDLVVVSPDVGGVARARAFAKKLsDAPLAIVDKRR-SGHNVAEVMNLIGDVRGKVAIMVDDMIDTAGTIVKGAALLHQEG 279
Cdd:TIGR01251 159 DNPVVVSPDAGGVERAKKVADAL-GCPLAIIDKRRiSATNEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAG 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15226977 280 AREVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLPVaeKNYFPQLTILSVANLLGETIWRVHDDSSVSSIF 351
Cdd:TIGR01251 238 AKRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPH--EKHKPKVSVISVAPLIAEAIRRIHNNESVSSLF 307
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
42-158 |
1.30e-73 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 223.45 E-value: 1.30e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 42 LKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNENLMELLIMVDACRRASAK 121
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|....*..
gi 15226977 122 KVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAG 158
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDKPREPITAKLVADLLEAAG 117
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
201-313 |
8.12e-24 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 94.77 E-value: 8.12e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 201 EDLVVVSPDVGGVARARAFAKKLsDAPLAIVDKRRSGHNVAEVM------NLIGDVRGKVAIMVDDMIDTAGTIVKGAAL 274
Cdd:cd06223 15 EPDVVVGILRGGLPLAAALARAL-GLPLAFIRKERKGPGRTPSEpyglelPLGGDVKGKRVLLVDDVIATGGTLLAAIEL 93
|
90 100 110
....*....|....*....|....*....|....*....
gi 15226977 275 LHQEGAREVYACCTHAVFSPPAIERLSGGLlqEVIVTNT 313
Cdd:cd06223 94 LKEAGAKVVGVAVLLDKPEGGARELASPGD--PVYSLFT 130
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02369 |
PLN02369 |
ribose-phosphate pyrophosphokinase |
51-352 |
0e+00 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 215209 [Multi-domain] Cd Length: 302 Bit Score: 630.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 51 PALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNENLMELLIMVDACRRASAKKVTAVIPYF 130
Cdd:PLN02369 1 PALSQEIACYLGLELGKITIKRFADGEIYVQLQESVRGCDVFLVQPTCPPANENLMELLIMIDACRRASAKRITAVIPYF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 131 GYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSIPSEDLVVVSPDV 210
Cdd:PLN02369 81 GYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKTISSPDLVVVSPDV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 211 GGVARARAFAKKLSDAPLAIVDKRRSGHNVAEVMNLIGDVRGKVAIMVDDMIDTAGTIVKGAALLHQEGAREVYACCTHA 290
Cdd:PLN02369 161 GGVARARAFAKKLSDAPLAIVDKRRQGHNVAEVMNLIGDVKGKVAIMVDDMIDTAGTITKGAALLHQEGAREVYACATHA 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15226977 291 VFSPPAIERLSGGLLQEVIVTNTLPVAEKNYFPQLTILSVANLLGETIWRVHDDSSVSSIFL 352
Cdd:PLN02369 241 VFSPPAIERLSSGLFQEVIVTNTIPVSEKNYFPQLTVLSVANLLGETIWRVHDDCSVSSIFD 302
|
|
| PRK02812 |
PRK02812 |
ribose-phosphate pyrophosphokinase; Provisional |
26-351 |
0e+00 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235072 [Multi-domain] Cd Length: 330 Bit Score: 589.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 26 LESARMEKSVNRTNtRLKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNENL 105
Cdd:PRK02812 7 AARAEQLPLLSDNN-RLRLFSGSSNPALAQEVARYLGMDLGPMIRKRFADGELYVQIQESIRGCDVYLIQPTCAPVNDHL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 106 MELLIMVDACRRASAKKVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYC 185
Cdd:PRK02812 86 MELLIMVDACRRASARQITAVIPYYGYARADRKTAGRESITAKLVANLITKAGADRVLAMDLHSAQIQGYFDIPCDHVYG 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 186 QPVILDYLASKSIPseDLVVVSPDVGGVARARAFAKKLSDAPLAIVDKRRSGHNVAEVMNLIGDVRGKVAIMVDDMIDTA 265
Cdd:PRK02812 166 SPVLLDYLASKNLE--DIVVVSPDVGGVARARAFAKKLNDAPLAIIDKRRQAHNVAEVLNVIGDVKGKTAILVDDMIDTG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 266 GTIVKGAALLHQEGAREVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLPVAEKNYFPQLTILSVANLLGETIWRVHDDS 345
Cdd:PRK02812 244 GTICEGARLLRKEGAKQVYACATHAVFSPPAIERLSSGLFEEVIVTNTIPVPEERRFPQLKVLSVANMLGEAIWRIHEES 323
|
....*.
gi 15226977 346 SVSSIF 351
Cdd:PRK02812 324 SVSSMF 329
|
|
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
39-351 |
0e+00 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 541.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 39 NTRLKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNENLMELLIMVDACRRA 118
Cdd:COG0462 1 MKDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 119 SAKKVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSI 198
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSKDL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 199 psEDLVVVSPDVGGVARARAFAKKLsDAPLAIVDKRRSGHNVAEVMNLIGDVRGKVAIMVDDMIDTAGTIVKGAALLHQE 278
Cdd:COG0462 161 --EDLVVVSPDVGGVKRARAFAKRL-GAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEA 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15226977 279 GAREVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLPVAEKNYFPQLTILSVANLLGETIWRVHDDSSVSSIF 351
Cdd:COG0462 238 GAKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEEKRCDKIKVLSVAPLLAEAIRRIHEGESVSSLF 310
|
|
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
42-351 |
0e+00 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 513.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 42 LKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNENLMELLIMVDACRRASAK 121
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 122 KVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSIpsE 201
Cdd:PRK01259 81 RITAVIPYFGYARQDRKARSRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQKNL--E 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 202 DLVVVSPDVGGVARARAFAKKLsDAPLAIVDKRRSGHNVAEVMNLIGDVRGKVAIMVDDMIDTAGTIVKGAALLHQEGAR 281
Cdd:PRK01259 159 NLVVVSPDVGGVVRARALAKRL-DADLAIIDKRRPRANVSEVMNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKERGAK 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15226977 282 EVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLPVAEK-NYFPQLTILSVANLLGETIWRVHDDSSVSSIF 351
Cdd:PRK01259 238 SVYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEaKKCDKIRVLSVAPLLAEAIRRISNEESVSSLF 308
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
42-351 |
6.52e-154 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 434.78 E-value: 6.52e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 42 LKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLV-QPTCTPTNENLMELLIMVDACRRASA 120
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 121 KKVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLasKSIPS 200
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKSREPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYL--KKKIL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 201 EDLVVVSPDVGGVARARAFAKKLsDAPLAIVDKRR-SGHNVAEVMNLIGDVRGKVAIMVDDMIDTAGTIVKGAALLHQEG 279
Cdd:TIGR01251 159 DNPVVVSPDAGGVERAKKVADAL-GCPLAIIDKRRiSATNEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAG 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15226977 280 AREVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLPVaeKNYFPQLTILSVANLLGETIWRVHDDSSVSSIF 351
Cdd:TIGR01251 238 AKRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPH--EKHKPKVSVISVAPLIAEAIRRIHNNESVSSLF 307
|
|
| PRK02269 |
PRK02269 |
ribose-phosphate diphosphokinase; |
40-351 |
3.52e-130 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 167353 [Multi-domain] Cd Length: 320 Bit Score: 374.90 E-value: 3.52e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 40 TRLKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNENLMELLIMVDACRRAS 119
Cdd:PRK02269 4 SDLKLFALSSNKELAEKVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRAS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 120 AKKVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSIP 199
Cdd:PRK02269 84 AESINVVMPYYGYARQDRKARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRRGLV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 200 SEDLVVVSPDVGGVARARAFAKKLSdAPLAIVDKRRSGH--NVAEVMNLIGDVRGKVAIMVDDMIDTAGTIVKGAALLHQ 277
Cdd:PRK02269 164 GDDVVVVSPDHGGVTRARKLAQFLK-TPIAIIDKRRSVDkmNTSEVMNIIGNVKGKKCILIDDMIDTAGTICHAADALAE 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15226977 278 EGAREVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLPVAEKNYFPQLTILSVANLLGETIWRVHDDSSVSSIF 351
Cdd:PRK02269 243 AGATEVYASCTHPVLSGPALDNIQKSAIEKLVVLDTIYLPEERLIDKIEQISIADLLGEAIIRIHEKRPLSPLF 316
|
|
| PRK03092 |
PRK03092 |
ribose-phosphate diphosphokinase; |
53-351 |
4.19e-130 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179535 [Multi-domain] Cd Length: 304 Bit Score: 374.28 E-value: 4.19e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 53 LAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNENLMELLIMVDACRRASAKKVTAVIPYFGY 132
Cdd:PRK03092 1 LAEEVAKELGVEVTPTTAYDFANGEIYVRFEESVRGCDAFVLQSHTAPINKWLMEQLIMIDALKRASAKRITVVLPFYPY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 133 ARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKsIPSEDLVVVSPDVGG 212
Cdd:PRK03092 81 ARQDKKHRGREPISARLVADLFKTAGADRIMTVDLHTAQIQGFFDGPVDHLFAMPLLADYVRDK-YDLDNVTVVSPDAGR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 213 VARARAFAKKLSDAPLAIVDKRRSG--HNVAEVMNLIGDVRGKVAIMVDDMIDTAGTIVKGAALLHQEGAREVYACCTHA 290
Cdd:PRK03092 160 VRVAEQWADRLGGAPLAFIHKTRDPtvPNQVVANRVVGDVEGRTCVLVDDMIDTGGTIAGAVRALKEAGAKDVIIAATHG 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15226977 291 VFSPPAIERLSGGLLQEVIVTNTLPVAEKNYFPQLTILSVANLLGETIWRVHDDSSVSSIF 351
Cdd:PRK03092 240 VLSGPAAERLKNCGAREVVVTDTLPIPEEKRFDKLTVLSIAPLLARAIREVFEDGSVTSLF 300
|
|
| PRK04923 |
PRK04923 |
ribose-phosphate diphosphokinase; |
42-352 |
2.15e-124 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179893 [Multi-domain] Cd Length: 319 Bit Score: 360.40 E-value: 2.15e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 42 LKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNENLMELLIMVDACRRASAK 121
Cdd:PRK04923 7 LLVFSGNANKPLAQSICKELGVRMGKALVTRFSDGEVQVEIEESVRRQEVFVIQPTCAPSAENLMELLVLIDALKRASAA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 122 KVTAVIPYFGYARADRKTQG-RESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLAsKSIPS 200
Cdd:PRK04923 87 SVTAVIPYFGYSRQDRRMRSsRVPITAKVAAKMISAMGADRVLTVDLHADQIQGFFDVPVDNVYASPLLLADIW-RAYGT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 201 EDLVVVSPDVGGVARARAFAKKLSDAPLAIVDKRRSGHNVAEVMNLIGDVRGKVAIMVDDMIDTAGTIVKGAALLHQEGA 280
Cdd:PRK04923 166 DNLIVVSPDVGGVVRARAVAKRLDDADLAIIDKRRPRANVATVMNIIGDVQGKTCVLVDDLVDTAGTLCAAAAALKQRGA 245
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15226977 281 REVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLPVAEK-NYFPQLTILSVANLLGETIWRVHDDSSVSSIFL 352
Cdd:PRK04923 246 LKVVAYITHPVLSGPAVDNINNSQLDELVVTDTIPLSEAaRACAKIRQLSVAELLAETIRRIAFGESVSSLYV 318
|
|
| PTZ00145 |
PTZ00145 |
phosphoribosylpyrophosphate synthetase; Provisional |
44-351 |
3.27e-113 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 240290 [Multi-domain] Cd Length: 439 Bit Score: 336.07 E-value: 3.27e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 44 LFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNENLMELLIMVDACRRASAKKV 123
Cdd:PTZ00145 122 LFSGSSNPLLSKNIADHLGTILGRVHLKRFADGEVSMQFLESIRGKDVYIIQPTCPPVNENLIELLLMISTCRRASAKKI 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 124 TAVIPYFGYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFD--IPVDHVYCQPVILDYLASKSIPSE 201
Cdd:PTZ00145 202 TAVIPYYGYARQDRKLSSRVPISAADVARMIEAMGVDRVVAIDLHSGQIQGFFGprVPVDNLEAQLIGLDYFTKKDLYKP 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 202 dlVVVSPDVGGVARARAFAKKL-----SDAPLAIVDKRRSGHNVAEVMNLIGDVRGKVAIMVDDMIDTAGTIVKGAALLH 276
Cdd:PTZ00145 282 --VIVSPDAGGVYRARKFQDGLnhrgiSDCGIAMLIKQRTKPNEIEKMDLVGNVYDSDVIIVDDMIDTSGTLCEAAKQLK 359
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15226977 277 QEGAREVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLPvAEKNY--FPQLTILSVANLLGETIWRVHDDSSVSSIF 351
Cdd:PTZ00145 360 KHGARRVFAFATHGLFSGPAIERIEASPLEEVVVTDTVK-SNKNIdsCKKITKLSVSVLVADAIRRIHQKESLNDLF 435
|
|
| PRK02458 |
PRK02458 |
ribose-phosphate pyrophosphokinase; Provisional |
42-351 |
1.47e-106 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235039 [Multi-domain] Cd Length: 323 Bit Score: 315.14 E-value: 1.47e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 42 LKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNENLMELLIMVDACRRASAK 121
Cdd:PRK02458 10 IKLFSLNSNLEIAEKIAQAAGVPLGKLSSRQFSDGEIMINIEESVRGDDIYIIQSTSFPVNDHLWELLIMIDACKRASAN 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 122 KVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSIPSE 201
Cdd:PRK02458 90 TVNVVLPYFGYARQDRIAKPREPITAKLVANMLVKAGVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCKKGLSGS 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 202 DLVVVSPDVGGVARARAFAKKLsDAPLAIVD------KRRSGHnvaevmnLIGDVRGKVAIMVDDMIDTAGTIVKGAALL 275
Cdd:PRK02458 170 DVVVVSPKNSGIKRARSLAEYL-DAPIAIIDyaqddsEREEGY-------IIGDVAGKKAILIDDILNTGKTFAEAAKIV 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15226977 276 HQEGAREVYACCTHAVFSPPAIERLSGGLLQEVIVTNTlpVAEKNYFPQ-LTILSVANLLGETIWRVHDDSSVSSIF 351
Cdd:PRK02458 242 EREGATEIYAVASHGLFAGGAAEVLENAPIKEILVTDS--VATKERVPKnVTYLSASELIADAIIRIHERKPLSPLF 316
|
|
| PRK00553 |
PRK00553 |
ribose-phosphate pyrophosphokinase; Provisional |
35-351 |
6.28e-103 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 179062 [Multi-domain] Cd Length: 332 Bit Score: 306.07 E-value: 6.28e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 35 VNRTNTRLKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNENLMELLIMVDA 114
Cdd:PRK00553 3 LSIDKSNHVIFSLSKAKKLVDSICRKLSMKPGEIVIQKFADGETYIRFDESVRNKDVVIFQSTCSPVNDSLMELLIAIDA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 115 CRRASAKKVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVD-----HVYCQPVI 189
Cdd:PRK00553 83 LKRGSAKSITAILPYYGYARQDRKTAGREPITSKLVADLLTKAGVTRVTLTDIHSDQTQGFFDIPVDilrtyHVFLSRVL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 190 LDylasksIPSEDLVVVSPDVGGVARARAFAKKLsDAPLAIVDKRRSGHNVAEVMNLIGDVRGKVAIMVDDMIDTAGTIV 269
Cdd:PRK00553 163 EL------LGKKDLVVVSPDYGGVKRARLIAESL-ELPLAIIDKRRPKHNVAESINVLGEVKNKNCLIVDDMIDTGGTVI 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 270 KGAALLHQEGAREVYACCTHAVFSPPAIERL----SGGLLQEVIVTNTLPVAEKNYFPQLTILSVANLLGETIWRVHDDS 345
Cdd:PRK00553 236 AAAKLLKKQKAKKVCVMATHGLFNKNAIQLFdeafKKKLIDKLFVSNSIPQTKFEKKPQFKVVDLAHLYEEVLLCYANGG 315
|
....*.
gi 15226977 346 SVSSIF 351
Cdd:PRK00553 316 SISAIY 321
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
42-158 |
1.30e-73 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 223.45 E-value: 1.30e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 42 LKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNENLMELLIMVDACRRASAK 121
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|....*..
gi 15226977 122 KVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAG 158
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDKPREPITAKLVADLLEAAG 117
|
|
| PRK00934 |
PRK00934 |
ribose-phosphate pyrophosphokinase; Provisional |
43-338 |
1.37e-69 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 234868 [Multi-domain] Cd Length: 285 Bit Score: 219.01 E-value: 1.37e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 43 KLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVyLVQPTCTPTNENLMELLIMVDACRRASAKK 122
Cdd:PRK00934 1 MIIGGSASQLLASEVARLLNTELALVETKRFPDGELYVRILGEIDGEDV-VIISTTYPQDENLVELLLLIDALRDEGAKS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 123 VTAVIPYFGYARADRKTQGRESIAAKLVANLItEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSipsED 202
Cdd:PRK00934 80 ITLVIPYLGYARQDKRFKPGEPISARAIAKII-SAYYDRIITINIHEPSILEFFPIPFINLDAAPLIAEYIGDKL---DD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 203 LVVVSPDVGGVARARAFAKKLSDAPLAIVDKRRSGHNVA-EVMNLigDVRGKVAIMVDDMIDTAGTIVKGAALLHQEGAR 281
Cdd:PRK00934 156 PLVLAPDKGALELAKEAAEILGCEYDYLEKTRISPTEVEiAPKNL--DVKGKDVLIVDDIISTGGTMATAIKILKEQGAK 233
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 15226977 282 EVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLPVAEknyfpqlTILSVANLLGETI 338
Cdd:PRK00934 234 KVYVACVHPVLVGDAILKLYNAGVDEIIVTDTLESEV-------SKISVAPLIADLL 283
|
|
| PRK06827 |
PRK06827 |
phosphoribosylpyrophosphate synthetase; Provisional |
67-350 |
1.80e-44 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 180714 [Multi-domain] Cd Length: 382 Bit Score: 157.04 E-value: 1.80e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 67 KVNIKRFADGEIYVQLQESVRGCDVYLVQPTC---------------TPtNENLMELLIMVDACRrASAKKVTAVIPYFG 131
Cdd:PRK06827 56 PAKFIRFSNGEAKGEILESVRGKDIYILQDVGnysvtynmfgeknhmSP-DDHFQDLKRTIDAIR-GKARRITVIMPFLY 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 132 YARADRKTqGRESIAAKLVANLITEAGADRVLACDLHSGQ-----SMGYFDIpvdhVYCQPVILDYLASK----SIPSED 202
Cdd:PRK06827 134 ESRQHKRK-GRESLDCALALQELEELGVDNIITFDAHDPRienaiPLMGFEN----LYPSYQIIKALLKNekdlEIDKDH 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 203 LVVVSPDVGGVARARAFAKKLSdAPLAIVDKRR------SGHNVAEVMNLIG-DVRGKVAIMVDDMIDTAGTIVKGAALL 275
Cdd:PRK06827 209 LMVISPDTGAMDRAKYYASVLG-VDLGLFYKRRdysrvvNGRNPIVAHEFLGrDVEGKDVLIVDDMIASGGSMIDAAKEL 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 276 HQEGAREVYACCTHAVFSpPAIERL----SGGLLQEVIVTN----TLPVAEKNYFpqlTILSVANLLGETIWRVHDDSSV 347
Cdd:PRK06827 288 KSRGAKKIIVAATFGFFT-NGLEKFdkayEEGYFDRIIGTNlvyhPEELLSKPWY---IEVDMSKLIARIIDALNHDVSL 363
|
...
gi 15226977 348 SSI 350
Cdd:PRK06827 364 SKL 366
|
|
| PRK07199 |
PRK07199 |
ribose-phosphate diphosphokinase; |
50-315 |
1.69e-40 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 235960 [Multi-domain] Cd Length: 301 Bit Score: 144.31 E-value: 1.69e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 50 NPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPtNENLMELLIMVDACRRASAKKVTAVIPY 129
Cdd:PRK07199 11 NEAAAGRLAAALGVEVGRIELHRFPDGESYVRLDSPVAGRTVVLVCSLDRP-DEKLLPLLFAAEAARELGARRVGLVAPY 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 130 FGYARADRKTQGRESIAAKLVANLITeAGADRVLACD--LHSGQSMG-YFDIPVDHVYCQPVILDYLASKSipsEDLVVV 206
Cdd:PRK07199 90 LAYMRQDIAFHPGEAISQRHFARLLS-GSFDRLVTVDphLHRYPSLSeVYPIPAVVLSAAPAIAAWIRAHV---PRPLLI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 207 SPD------VGGVARarafakkLSDAPLAIVDKRRSGHNVAEV--MNLIGdVRGKVAIMVDDMIDTAGTIVKGAALLHQE 278
Cdd:PRK07199 166 GPDeeseqwVAAVAE-------RAGAPHAVLRKTRHGDRDVEIslPDAAP-WAGRTPVLVDDIVSTGRTLIEAARQLRAA 237
|
250 260 270
....*....|....*....|....*....|....*..
gi 15226977 279 GAREVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLP 315
Cdd:PRK07199 238 GAASPDCVVVHALFAGDAYSALAAAGIARVVSTDTVP 274
|
|
| Pribosyl_synth |
pfam14572 |
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ... |
204-351 |
2.96e-24 |
|
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.
Pssm-ID: 434046 Cd Length: 184 Bit Score: 97.97 E-value: 2.96e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 204 VVVSPDVGGVARARAFAKKL-----------SDAPLAIVDKR--------RSGHNVAEV----------MNLIGDVRGKV 254
Cdd:pfam14572 6 VIVARSPGSAKRATSFAERLrlgiavihgeqKEAESDEVDGRqspppyrsRTVSRSLGLpeiipkekppMTVVGDVGGRI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 255 AIMVDDMIDTAGTIVKGAALLHQEGAREVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLP-VAEKNYFPQLTILSVANL 333
Cdd:pfam14572 86 AIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPhEIQKMQCHKIKTIDISQL 165
|
170
....*....|....*...
gi 15226977 334 LGETIWRVHDDSSVSSIF 351
Cdd:pfam14572 166 IAEAIRRIHNGESMSYLF 183
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
201-313 |
8.12e-24 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 94.77 E-value: 8.12e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 201 EDLVVVSPDVGGVARARAFAKKLsDAPLAIVDKRRSGHNVAEVM------NLIGDVRGKVAIMVDDMIDTAGTIVKGAAL 274
Cdd:cd06223 15 EPDVVVGILRGGLPLAAALARAL-GLPLAFIRKERKGPGRTPSEpyglelPLGGDVKGKRVLLVDDVIATGGTLLAAIEL 93
|
90 100 110
....*....|....*....|....*....|....*....
gi 15226977 275 LHQEGAREVYACCTHAVFSPPAIERLSGGLlqEVIVTNT 313
Cdd:cd06223 94 LKEAGAKVVGVAVLLDKPEGGARELASPGD--PVYSLFT 130
|
|
| Pribosyltran |
pfam00156 |
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl ... |
189-290 |
3.70e-15 |
|
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase. Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1. Amidophosphoribosyltransferase EC:2.4.2.14. Orotate phosphoribosyl-transferase EC:2.4.2.10. Uracil phosphoribosyl-transferase EC:2.4.2.9. Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22. In Arabidopsis, At the very N-terminus of this domain is the P-Loop NTPase domain.
Pssm-ID: 425489 [Multi-domain] Cd Length: 150 Bit Score: 72.01 E-value: 3.70e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 189 ILDYLASK---SIPSEDLVVVSPDVGGVARARAFAKKLsDAPLAIVDKRRSGHNVAEVM---NLIGDVRGKVAIMVDDMI 262
Cdd:pfam00156 14 AVARLAAQineDYGGKPDVVVGILRGGLPFAGILARRL-DVPLAFVRKVSYNPDTSEVMktsSALPDLKGKTVLIVDDIL 92
|
90 100
....*....|....*....|....*...
gi 15226977 263 DTAGTIVKGAALLHQEGAREVYACCTHA 290
Cdd:pfam00156 93 DTGGTLLKVLELLKNVGPKEVKIAVLID 120
|
|
| PLN02297 |
PLN02297 |
ribose-phosphate pyrophosphokinase |
37-331 |
1.08e-14 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 177934 [Multi-domain] Cd Length: 326 Bit Score: 73.96 E-value: 1.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 37 RTNTRLKLFSGTANPALAQEIAWYMG-LDLGKVNIKRFADG--EIYVQLQESVRGCDVYLVQPTCTPtnENLMELLIMVD 113
Cdd:PLN02297 12 KNKKQVHLFYCEETEELARKIAAESDaIELGSINWRKFPDGfpNLFINNAHGIRGQHVAFLASFSSP--AVIFEQLSVIY 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 114 ACRRASAKKVTAVIPYFGYARADR-KTQGRESIA---AKLVANL-ITEAGADRVLACDLHSGQSMGYFDipvDHVY-C-- 185
Cdd:PLN02297 90 ALPKLFVASFTLVLPFFPTGTSERvEREGDVATAftlARILSNIpISRGGPTSLVIFDIHALQERFYFG---DNVLpCfe 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15226977 186 --QPVILDYLasKSIP-SEDLVVVSPDVGGVARaraFAKKLSDAPLAIVDKRRSGhNVAEVMNLIGDVRGKVAIMVDDMI 262
Cdd:PLN02297 167 sgIPLLKKRL--QQLPdSDNIVIAFPDDGAWKR---FHKQFEHFPMVVCTKVREG-DKRIVRIKEGNPAGRHVVIVDDLV 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15226977 263 DTAGTIVKGAALLHQEGAREVYACCTHAVFSPPAIERL------SGGLLQEVIVTNTLP--VAEKNYFPQLTILSVA 331
Cdd:PLN02297 241 QSGGTLIECQKVLAAHGAAKVSAYVTHGVFPNESWERFthdnggPEAGFAYFWITDSCPqtVKAVRGKAPFEVLSLA 317
|
|
| PLN02238 |
PLN02238 |
hypoxanthine phosphoribosyltransferase |
249-288 |
6.36e-03 |
|
hypoxanthine phosphoribosyltransferase
Pssm-ID: 215132 Cd Length: 189 Bit Score: 37.32 E-value: 6.36e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 15226977 249 DVRGKVAIMVDDMIDTAGTIVKGAALLHQEGAREVyACCT 288
Cdd:PLN02238 94 DVKGKHVLLVEDIVDTGNTLSALVAHLEAKGAASV-SVCA 132
|
|
| upp |
PRK00129 |
uracil phosphoribosyltransferase; Reviewed |
246-300 |
9.11e-03 |
|
uracil phosphoribosyltransferase; Reviewed
Pssm-ID: 234653 Cd Length: 209 Bit Score: 36.99 E-value: 9.11e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 15226977 246 LIGDVRGKVAIMVDDMIDTAGTIVKGAALLHQEGAREVYACCthAVFSPPAIERL 300
Cdd:PRK00129 118 LPEDIDERTVIVVDPMLATGGSAIAAIDLLKKRGAKNIKVLC--LVAAPEGIKAL 170
|
|
| |
