|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
97-932 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1149.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 97 DESRIVPFELHKEATESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDT 176
Cdd:PRK05560 1 EGDRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 177 AVYDSLVRMAQSFSLRCPLIQGHGNFGSIDADPPAAMRYTECRLDPLAEAvLLSDLDQDTVDFVANFDNSQKEPAVLPAR 256
Cdd:PRK05560 81 AVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHE-LLADIDKETVDFVPNYDGSEQEPTVLPAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 257 LPALLLNGASGIAVGMATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPAPDFPTGGIIMGNLGVLDAYRTGRGRVVV 336
Cdd:PRK05560 160 FPNLLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 337 RGKAEVElldPKTKRNAVIITEIPYQTNKATLVQKIAELVENKTLEGISDIRDESDRNGMRVVIELKRGGDPALVLNNLY 416
Cdd:PRK05560 240 RAKAEIE---EIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDGMRIVIELKRDAVPEVVLNNLY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 417 RHTALQSSFSCNMVGICDGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIELITKAS 496
Cdd:PRK05560 317 KHTQLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASP 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 497 SHSSATAALQSEYGLSEKQAEAILEITLRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLIEQEAIELKDRFSS 576
Cdd:PRK05560 397 TPAEAKEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGD 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 577 PRRSMLEDsDSGDLEDIDVIPNEEMLMAVSEKGYVKRMKADTFNLQHRGTIGKSVGKLRVDDAMSDFLVCHAHDHVLFFS 656
Cdd:PRK05560 477 PRRTEIIE-GEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFT 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 657 DRGIVYSTRAYKIPECSRNAAGTPLVQILSMSEGERVTSIVPVSEFAEDRYLLMLTVNGCIKKVSLKLFSGIRSTGIIAI 736
Cdd:PRK05560 556 NRGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAI 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 737 QLNSGDELKWVRCCSSDDLVAMASQNGMVALSTCDGVRTLSRNTKGVTAMRLKNEDKIASMDIIPaslrkdmeeksedas 816
Cdd:PRK05560 636 NLDEGDELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVRGIKLREGDEVVSMDVVR--------------- 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 817 lvkqSTGPWLLFVCENGYGKRVPLSSFRRSRLNRVGLSGYKFAED-DRLAAVFVVgyslaedgESDEQVVLVSQSGTVNR 895
Cdd:PRK05560 701 ----EDSQEILTVTENGYGKRTPVSEYRLQGRGGKGVITIKITEKnGKLVGALPV--------DDDDEIMLITDSGKLIR 768
|
810 820 830
....*....|....*....|....*....|....*..
gi 30681440 896 IKVRDISIQSRRARGVILMRLDHAGKIQSASLISAAD 932
Cdd:PRK05560 769 TRVSEISITGRNTQGVRLIRLDEGDKVVSVARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
97-925 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1125.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 97 DESRIVPFELHKEATESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDT 176
Cdd:COG0188 6 PAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYHPHGDS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 177 AVYDSLVRMAQSFSLRCPLIQGHGNFGSIDADPPAAMRYTECRLDPLAEAvLLSDLDQDTVDFVANFDNSQKEPAVlpar 256
Cdd:COG0188 86 AVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEE-LLADIDKDTVDFVPNYDGSEQEPTVlpar 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 257 lpalllNGASGIAVGMATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPAPDFPTGGIIMGNLGVLDAYRTGRGRVVV 336
Cdd:COG0188 165 fpnllvNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRGSIRV 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 337 RGKAEVEllDPKTKRNAVIITEIPYQTNKATLVQKIAELVENKTLEGISDIRDESDRNGMRVVIELKRGGDPALVLNNLY 416
Cdd:COG0188 245 RAKAEIE--ELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLNQLY 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 417 RHTALQSSFSCNMVGICDGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIELITKAS 496
Cdd:COG0188 323 KHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIRASK 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 497 SHSSATAALQSEYGLSEKQAEAILEITLRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLIEQEAIELKDRFSS 576
Cdd:COG0188 403 DPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIKKKYGD 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 577 PRRSMLEDSDsGDLEDIDVIPNEEMLMAVSEKGYVKRMKADTFNLQHRGTIGKSVGKLRVDDAMSDFLVCHAHDHVLFFS 656
Cdd:COG0188 483 ERRTEIEEAE-GEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFT 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 657 DRGIVYSTRAYKIPECSRNAAGTPLVQILSMSEGERVTSIVPVSEFAEDRYLLMLTVNGCIKKVSLKLFSGIRSTGIIAI 736
Cdd:COG0188 562 NKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAI 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 737 QLNSGDELKWVRCCSSDDLVAMASQNGMVALSTCDGVRTLSRNTKGVTAMRLKNEDKIASMDIIPAslrkdmeeksedas 816
Cdd:COG0188 642 NLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTARGVRGIRLKEGDEVVGMAVVDE-------------- 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 817 lvkqstGPWLLFVCENGYGKRVPLSSFRRSRLNRVGLSGYKFAE-DDRLAAVFVVgyslaedgESDEQVVLVSQSGTVNR 895
Cdd:COG0188 708 ------EDDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEkNGKLVGALVV--------NDDDELMLITSSGQLIR 773
|
810 820 830
....*....|....*....|....*....|
gi 30681440 896 IKVRDISIQSRRARGVILMRLDHAGKIQSA 925
Cdd:COG0188 774 TPVSDIRVTGRNTQGVRLIRLDEGDKVVSV 803
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
101-929 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1019.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 101 IVPFELHKEATESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDTAVYD 180
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 181 SLVRMAQSFSLRCPLIQGHGNFGSIDADPPAAMRYTECRLDPLAEAvLLSDLDQDTVDFVANFDNSQKEPAVLPARLPAL 260
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEE-LLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 261 LLNGASGIAVGMATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPAPDFPTGGIIMGNLGVLDAYRTGRGRVVVRGKA 340
Cdd:TIGR01063 160 LVNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 341 EVELLdpKTKRNAVIITEIPYQTNKATLVQKIAELVENKTLEGISDIRDESDRNGMRVVIELKRGGDPALVLNNLYRHTA 420
Cdd:TIGR01063 240 EIEED--SKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREGIRIVIELKRDAVAEVVLNNLYKQTQ 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 421 LQSSFSCNMVGICDGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIELITKASSHSS 500
Cdd:TIGR01063 318 LQVSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEE 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 501 ATAALQSEYGLSEKQAEAILEITLRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLIEQEAIELKDRFSSPRRS 580
Cdd:TIGR01063 398 AKTRLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPRRT 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 581 MLEDSDSGDLEDIDVIPNEEMLMAVSEKGYVKRMKADTFNLQHRGTIGKSVGKLRVDDAMSDFLVCHAHDHVLFFSDRGI 660
Cdd:TIGR01063 478 EIVYDESEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNRGK 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 661 VYSTRAYKIPECSRNAAGTPLVQILSMSEGERVTSIVPVSEFAEDRYLLMLTVNGCIKKVSLKLFSGIRSTGIIAIQLNS 740
Cdd:TIGR01063 558 VYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKLDD 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 741 GDELKWVRCCSSDDLVAMASQNGMVALSTCDGVRTLSRNTKGVTAMRLKNEDKIASMDIIpaslrkdmeeksedaslvkq 820
Cdd:TIGR01063 638 GDELISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIKLKNEDFVVSLLVV-------------------- 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 821 STGPWLLFVCENGYGKRVPLSSFRRSRLNRVGLSGYKFAE-DDRLAAVFVVgyslaedgESDEQVVLVSQSGTVNRIKVR 899
Cdd:TIGR01063 698 SEESYLLIVTENGYGKRTSIEEYRETSRGGKGVKSIKITDrNGQVVGAIAV--------DDDDELMLITSAGKLIRTSVQ 769
|
810 820 830
....*....|....*....|....*....|
gi 30681440 900 DISIQSRRARGVILMRLDHAGKIQSASLIS 929
Cdd:TIGR01063 770 DVSEQGRNTQGVRLIRLDEDDKLVSVSKVA 799
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
124-570 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 618.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 124 GRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDTAVYDSLVRMAQSFSLRCPLIQGHGNFG 203
Cdd:cd00187 2 GRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNFG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 204 SIDADPPAAMRYTECRLDPLAEaVLLSDLDQDTVDFVANFDNSQKEPAVLPARLPALLLNGASGIAVGMATNIPPHNLGE 283
Cdd:cd00187 82 SRDGDDAAAMRYTETRLSPIAR-LLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 284 LVDVLCALIHNPEATLQELLEYMPAPDFPTGGIIMGNLGVLDAYRTGRGRVVVRGKAEVElldPKTKRNAVIITEIPYQT 363
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIE---DDEGRNTIEITELPYQV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 364 NKATLVQKIAELVENKTLEGISDIRDESDRNGMRVVIELKRGGDPALVLNNLYRHTALQSSFSCNMVGI-CDGEPKLMGL 442
Cdd:cd00187 238 NKAKLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFdPNGRPKKLNL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 443 KELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIELITKASSHSSATAALQSEYGLSEKQAEAILEI 522
Cdd:cd00187 318 KEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSSDEAKKALIEELEKLGFSEIQADAILDM 397
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 30681440 523 TLRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLIEQEAIEL 570
Cdd:cd00187 398 RLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
125-563 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 599.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 125 RALPDVRDGLKPVHRRILFAMHELgMSSKKPYKKCARVVGEVLGKFHPHGDTAVYDSLVRMAQSFSLRCPLIQGHGNFGS 204
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFEL-LNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 205 -IDADPPAAMRYTECRLDPLAEAvLLSDLDQDTVDFVANFDNSQKEPAVLPARLPALLLNGASGIAVGMATNIPPHNLGE 283
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARE-LFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLRE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 284 LVDVLCALIHNPEATLqeLLEYMPAPDFPTGGIIMGNLGVLDAYRTGRGRVVVRGKAEVElldpktKRNAVIITEIPYQT 363
Cdd:pfam00521 159 IIDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIE------DRKTIVITELPYGV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 364 NKATLVQKIAELVENKTLEGISDIRDESDRnGMRVVIELKRGGDPALVLNNLYRHTALQSSFSCNMVGICDGEPKLMGLK 443
Cdd:pfam00521 231 WTSDLIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLK 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 444 ELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIELITKASSHSSATAALQSEygLSEKQAEAILEIT 523
Cdd:pfam00521 310 EILKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE--LSEIQADYLLDMR 387
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 30681440 524 LRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLI 563
Cdd:pfam00521 388 LRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLW 427
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
112-556 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 564.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 112 ESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDTAVYDSLVRMAQSFSL 191
Cdd:smart00434 9 KEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIVRMAQDFSN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 192 RCPLIQGHGNFGSI-DADPPAAMRYTECRLDPLAEaVLLSDLDQDTVDFVANFDNSQKEPAVLPARLPALLLNGASGIAV 270
Cdd:smart00434 89 NYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLAR-LLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVNGSSGIAV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 271 GMATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPAPDFPTGGIIMgnlgvldayrtGRGRVVVRGKAEVElldpktK 350
Cdd:smart00434 168 GMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE------D 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 351 RNAVIITEIPYQTNKATLVQKIAELVENKTLEGISDIRDES-DRNGMRVVIELKRGGDPALVLNNLYRHTALQSSFSCNM 429
Cdd:smart00434 231 DNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQTTFSINM 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 430 VGI-CDGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQ-RKHIIEGIVVGLDNVDEVIELI-TKASSHSSATAALQ 506
Cdd:smart00434 311 LALfDNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEAeRLHILEGLFIALSIIDEIIVLIrSSKDLAKEAKEKLM 390
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 30681440 507 SEYGLSEKQAEAILEITLRRLTALERKKFTDESSSLTEQITKLEQLLSTR 556
Cdd:smart00434 391 ERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASE 440
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
97-932 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1149.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 97 DESRIVPFELHKEATESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDT 176
Cdd:PRK05560 1 EGDRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 177 AVYDSLVRMAQSFSLRCPLIQGHGNFGSIDADPPAAMRYTECRLDPLAEAvLLSDLDQDTVDFVANFDNSQKEPAVLPAR 256
Cdd:PRK05560 81 AVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHE-LLADIDKETVDFVPNYDGSEQEPTVLPAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 257 LPALLLNGASGIAVGMATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPAPDFPTGGIIMGNLGVLDAYRTGRGRVVV 336
Cdd:PRK05560 160 FPNLLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 337 RGKAEVElldPKTKRNAVIITEIPYQTNKATLVQKIAELVENKTLEGISDIRDESDRNGMRVVIELKRGGDPALVLNNLY 416
Cdd:PRK05560 240 RAKAEIE---EIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDGMRIVIELKRDAVPEVVLNNLY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 417 RHTALQSSFSCNMVGICDGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIELITKAS 496
Cdd:PRK05560 317 KHTQLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASP 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 497 SHSSATAALQSEYGLSEKQAEAILEITLRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLIEQEAIELKDRFSS 576
Cdd:PRK05560 397 TPAEAKEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGD 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 577 PRRSMLEDsDSGDLEDIDVIPNEEMLMAVSEKGYVKRMKADTFNLQHRGTIGKSVGKLRVDDAMSDFLVCHAHDHVLFFS 656
Cdd:PRK05560 477 PRRTEIIE-GEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFT 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 657 DRGIVYSTRAYKIPECSRNAAGTPLVQILSMSEGERVTSIVPVSEFAEDRYLLMLTVNGCIKKVSLKLFSGIRSTGIIAI 736
Cdd:PRK05560 556 NRGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAI 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 737 QLNSGDELKWVRCCSSDDLVAMASQNGMVALSTCDGVRTLSRNTKGVTAMRLKNEDKIASMDIIPaslrkdmeeksedas 816
Cdd:PRK05560 636 NLDEGDELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVRGIKLREGDEVVSMDVVR--------------- 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 817 lvkqSTGPWLLFVCENGYGKRVPLSSFRRSRLNRVGLSGYKFAED-DRLAAVFVVgyslaedgESDEQVVLVSQSGTVNR 895
Cdd:PRK05560 701 ----EDSQEILTVTENGYGKRTPVSEYRLQGRGGKGVITIKITEKnGKLVGALPV--------DDDDEIMLITDSGKLIR 768
|
810 820 830
....*....|....*....|....*....|....*..
gi 30681440 896 IKVRDISIQSRRARGVILMRLDHAGKIQSASLISAAD 932
Cdd:PRK05560 769 TRVSEISITGRNTQGVRLIRLDEGDKVVSVARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
97-925 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1125.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 97 DESRIVPFELHKEATESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDT 176
Cdd:COG0188 6 PAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYHPHGDS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 177 AVYDSLVRMAQSFSLRCPLIQGHGNFGSIDADPPAAMRYTECRLDPLAEAvLLSDLDQDTVDFVANFDNSQKEPAVlpar 256
Cdd:COG0188 86 AVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEE-LLADIDKDTVDFVPNYDGSEQEPTVlpar 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 257 lpalllNGASGIAVGMATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPAPDFPTGGIIMGNLGVLDAYRTGRGRVVV 336
Cdd:COG0188 165 fpnllvNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRGSIRV 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 337 RGKAEVEllDPKTKRNAVIITEIPYQTNKATLVQKIAELVENKTLEGISDIRDESDRNGMRVVIELKRGGDPALVLNNLY 416
Cdd:COG0188 245 RAKAEIE--ELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLNQLY 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 417 RHTALQSSFSCNMVGICDGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIELITKAS 496
Cdd:COG0188 323 KHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIRASK 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 497 SHSSATAALQSEYGLSEKQAEAILEITLRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLIEQEAIELKDRFSS 576
Cdd:COG0188 403 DPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIKKKYGD 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 577 PRRSMLEDSDsGDLEDIDVIPNEEMLMAVSEKGYVKRMKADTFNLQHRGTIGKSVGKLRVDDAMSDFLVCHAHDHVLFFS 656
Cdd:COG0188 483 ERRTEIEEAE-GEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFT 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 657 DRGIVYSTRAYKIPECSRNAAGTPLVQILSMSEGERVTSIVPVSEFAEDRYLLMLTVNGCIKKVSLKLFSGIRSTGIIAI 736
Cdd:COG0188 562 NKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAI 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 737 QLNSGDELKWVRCCSSDDLVAMASQNGMVALSTCDGVRTLSRNTKGVTAMRLKNEDKIASMDIIPAslrkdmeeksedas 816
Cdd:COG0188 642 NLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTARGVRGIRLKEGDEVVGMAVVDE-------------- 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 817 lvkqstGPWLLFVCENGYGKRVPLSSFRRSRLNRVGLSGYKFAE-DDRLAAVFVVgyslaedgESDEQVVLVSQSGTVNR 895
Cdd:COG0188 708 ------EDDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEkNGKLVGALVV--------NDDDELMLITSSGQLIR 773
|
810 820 830
....*....|....*....|....*....|
gi 30681440 896 IKVRDISIQSRRARGVILMRLDHAGKIQSA 925
Cdd:COG0188 774 TPVSDIRVTGRNTQGVRLIRLDEGDKVVSV 803
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
101-929 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1019.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 101 IVPFELHKEATESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDTAVYD 180
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 181 SLVRMAQSFSLRCPLIQGHGNFGSIDADPPAAMRYTECRLDPLAEAvLLSDLDQDTVDFVANFDNSQKEPAVLPARLPAL 260
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEE-LLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 261 LLNGASGIAVGMATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPAPDFPTGGIIMGNLGVLDAYRTGRGRVVVRGKA 340
Cdd:TIGR01063 160 LVNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 341 EVELLdpKTKRNAVIITEIPYQTNKATLVQKIAELVENKTLEGISDIRDESDRNGMRVVIELKRGGDPALVLNNLYRHTA 420
Cdd:TIGR01063 240 EIEED--SKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREGIRIVIELKRDAVAEVVLNNLYKQTQ 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 421 LQSSFSCNMVGICDGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIELITKASSHSS 500
Cdd:TIGR01063 318 LQVSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEE 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 501 ATAALQSEYGLSEKQAEAILEITLRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLIEQEAIELKDRFSSPRRS 580
Cdd:TIGR01063 398 AKTRLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPRRT 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 581 MLEDSDSGDLEDIDVIPNEEMLMAVSEKGYVKRMKADTFNLQHRGTIGKSVGKLRVDDAMSDFLVCHAHDHVLFFSDRGI 660
Cdd:TIGR01063 478 EIVYDESEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNRGK 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 661 VYSTRAYKIPECSRNAAGTPLVQILSMSEGERVTSIVPVSEFAEDRYLLMLTVNGCIKKVSLKLFSGIRSTGIIAIQLNS 740
Cdd:TIGR01063 558 VYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKLDD 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 741 GDELKWVRCCSSDDLVAMASQNGMVALSTCDGVRTLSRNTKGVTAMRLKNEDKIASMDIIpaslrkdmeeksedaslvkq 820
Cdd:TIGR01063 638 GDELISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIKLKNEDFVVSLLVV-------------------- 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 821 STGPWLLFVCENGYGKRVPLSSFRRSRLNRVGLSGYKFAE-DDRLAAVFVVgyslaedgESDEQVVLVSQSGTVNRIKVR 899
Cdd:TIGR01063 698 SEESYLLIVTENGYGKRTSIEEYRETSRGGKGVKSIKITDrNGQVVGAIAV--------DDDDELMLITSAGKLIRTSVQ 769
|
810 820 830
....*....|....*....|....*....|
gi 30681440 900 DISIQSRRARGVILMRLDHAGKIQSASLIS 929
Cdd:TIGR01063 770 DVSEQGRNTQGVRLIRLDEDDKLVSVSKVA 799
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
97-793 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 766.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 97 DESRIVPFELHKEATESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDT 176
Cdd:PRK05561 6 MLEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPHGDS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 177 AVYDSLVRMAQSFSLRCPLIQGHGNFGSIDADPPAAMRYTECRLDPLAEaVLLSDLDQDTVDFVANFDNSQKEPAVLPAR 256
Cdd:PRK05561 86 SIYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAE-LLLEEIDEGTVDFVPNFDGTLKEPTVLPAR 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 257 LPALLLNGASGIAVGMATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPAPDFPTGG-IIMGNLGVLDAYRTGRGRVV 335
Cdd:PRK05561 165 FPNLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELMEFVPGPDFPTGGeIITGRDGIRKAYETGRGSIR 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 336 VRGKAEVEllDPKTKRNAVIITEIPYQTNKATLVQKIAELVENKTLEGISDIRDESDR-NGMRVVIELK-RGGDPALVLN 413
Cdd:PRK05561 245 VRARWEIE--DLAGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDReNPVRIVIEPKsNRVDPEALMN 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 414 NLYRHTALQSSFSCNMVGIC-DGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIELI 492
Cdd:PRK05561 323 HLFATTDLESSYRVNMNAIGlDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIRII 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 493 -----TKasshssatAALQSEYGLSEKQAEAILEITLRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLIEQEA 567
Cdd:PRK05561 403 resdePK--------ANLMARFDLSEIQAEAILELRLRRLAKLEEIEIRKEQDELRKEIAELEAILASERKLRKLIKKEL 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 568 IELKDRFSSPRRSMLEDSDSGDLEDI-DVIPNEEMLMAVSEKGYVKRMKADTFNLqhrgtigkSVGKLRVDDAMSDFLVC 646
Cdd:PRK05561 475 KADAKKFGDPRRTPIEEAEEAIAIDEeALIPDEPVTVVLSKKGWVRRAKGHSIDA--------SGLSFKEGDSLLFAFEA 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 647 HAHDHVLFFSDRGIVYSTRAYKIPECSRNaaGTPLVQILSMSEGERVTSIVPvseFAEDRYLLMLTVNGCIKKVSLKLFS 726
Cdd:PRK05561 547 RTTDKLLLFTSTGRVYSLPVHELPSARGD--GEPLTGLVDLAPGEEIVHVLA---FDPDQKLLLASSAGYGFVVTLEDLV 621
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30681440 727 GIRSTGIIAIQLNSGDELKWVRCCSSDDLVAMASQNGMVALSTCDGVRTLSRnTKGVTAMRLKNEDK 793
Cdd:PRK05561 622 ARTRAGKAVINLKDGDEVLPPVPVEDDDHLAAITSNGRLLVFPLSELPELGK-GKGVKLINLPKDDD 687
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
124-570 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 618.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 124 GRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDTAVYDSLVRMAQSFSLRCPLIQGHGNFG 203
Cdd:cd00187 2 GRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNFG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 204 SIDADPPAAMRYTECRLDPLAEaVLLSDLDQDTVDFVANFDNSQKEPAVLPARLPALLLNGASGIAVGMATNIPPHNLGE 283
Cdd:cd00187 82 SRDGDDAAAMRYTETRLSPIAR-LLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 284 LVDVLCALIHNPEATLQELLEYMPAPDFPTGGIIMGNLGVLDAYRTGRGRVVVRGKAEVElldPKTKRNAVIITEIPYQT 363
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIE---DDEGRNTIEITELPYQV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 364 NKATLVQKIAELVENKTLEGISDIRDESDRNGMRVVIELKRGGDPALVLNNLYRHTALQSSFSCNMVGI-CDGEPKLMGL 442
Cdd:cd00187 238 NKAKLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFdPNGRPKKLNL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 443 KELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIELITKASSHSSATAALQSEYGLSEKQAEAILEI 522
Cdd:cd00187 318 KEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSSDEAKKALIEELEKLGFSEIQADAILDM 397
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 30681440 523 TLRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLIEQEAIEL 570
Cdd:cd00187 398 RLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
125-563 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 599.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 125 RALPDVRDGLKPVHRRILFAMHELgMSSKKPYKKCARVVGEVLGKFHPHGDTAVYDSLVRMAQSFSLRCPLIQGHGNFGS 204
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFEL-LNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 205 -IDADPPAAMRYTECRLDPLAEAvLLSDLDQDTVDFVANFDNSQKEPAVLPARLPALLLNGASGIAVGMATNIPPHNLGE 283
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARE-LFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLRE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 284 LVDVLCALIHNPEATLqeLLEYMPAPDFPTGGIIMGNLGVLDAYRTGRGRVVVRGKAEVElldpktKRNAVIITEIPYQT 363
Cdd:pfam00521 159 IIDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIE------DRKTIVITELPYGV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 364 NKATLVQKIAELVENKTLEGISDIRDESDRnGMRVVIELKRGGDPALVLNNLYRHTALQSSFSCNMVGICDGEPKLMGLK 443
Cdd:pfam00521 231 WTSDLIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLK 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 444 ELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIELITKASSHSSATAALQSEygLSEKQAEAILEIT 523
Cdd:pfam00521 310 EILKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE--LSEIQADYLLDMR 387
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 30681440 524 LRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLI 563
Cdd:pfam00521 388 LRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLW 427
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
98-935 |
0e+00 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 589.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 98 ESRIVPFELHKEATESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDTA 177
Cdd:PRK13979 10 DNNIIKIPLEEAMPENYLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPHGDSS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 178 VYDSLVRMAQSFSLRCPLIQGHGNFGSIDADPPAAMRYTECRLDPLAEAvLLSDLDQDTVDFVANFDNSQKEPAVLPARL 257
Cdd:PRK13979 90 VYDAMVILAQDFTTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAME-MLRDIDKDVVNMVDNYSDSEKEPEVLPARY 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 258 PALLLNGASGIAVGMATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPAPDFPTGGIIMGNLGVLDAYRTGRGRVVVR 337
Cdd:PRK13979 169 PNLLVNGAFGIAVGLATNIPPHNLKEVIDGTLAYIDNNEITTKELMNYIKGPDLPTGGILIGKKSLLSAYETGEGKVTLR 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 338 GKAEVELLDpkTKRNAVIITEIPYQTNKATLVQKIAELVENK----TLEGISDIRDESDRNGMRVVIELKRGGDPAL--- 410
Cdd:PRK13979 249 AKTKIEKLE--NGRLGIVITEFPYRRNKAKLLQTISEMTADKkhskALENISDIRDESDRNGIRAVIEFKKSADEDVaek 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 411 VLNNLYRHTALQSSFSCNMVGICDGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIE 490
Cdd:PRK13979 327 VLKYLYKKTDLQCNISFNMVALADGKPETMGLKTMLKHYVEHQKEVVTRRTKKELEIAEKRFHIVEGFIKAIGIMDEIIK 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 491 LITKASSHSSATAALQSEYGLSEKQAEAILEITLRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLIEQEAIEL 570
Cdd:PRK13979 407 TIRSSKSKKDASENLIEKFGFTDEQAEAILELMLYRLTGLEIVAFEKEYKELEKLIKKLTKILSSEKELLKVIKKELKEV 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 571 KDRFSSPRRSMLEDSDSG---DLEDIdvIPNEEMLMAVSEKGYVKRMKADTFNlqhRGTIGKSVGKLRVDDAMSDFLVCH 647
Cdd:PRK13979 487 KEKYGDERRTSIIEDDEKakiDVEEL--IVVEDVVITLSNEGFIKRIPLKSYN---RSNSNVEDIEYREGDFNKFLIQSN 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 648 AHDHVLFFSDRGIVYSTRAYKIPECSRNAAGTPLVQIL-SMS-EGERVTSIVPVSEFAEDRYLLMLTVNGCIKKVSLKLF 725
Cdd:PRK13979 562 TKDTLLIFTDKGNMYQIKGINIPEFKWKEKGERLDEIIkGIDlESEKIIEAYSIEDFTPQKDFIFITDSGGIKKTSLDKF 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 726 SGIRSTgIIAIQLNSGDEL---KWVRCCSSDDLVAMASQNGmvaLSTCDGVRTLS---RNTKGVTAMRLKNEDKIASMDI 799
Cdd:PRK13979 642 VTNYTK-LMALKLKKGEKLikvKLVDRTREEKFIKIKTKKG---LSFTVEEPELEpvdRNIIGYQLFDLLPNDSIKKVDF 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 800 ---------------------------------------------------IPASLRKDME-----------EKSEDASL 817
Cdd:PRK13979 718 cdnyeykefyvninkkgiikisdkdnkssisvftnssknllifsdegkvykIPAFMLQNIKneginisaltgDFEKDEKI 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 818 VKQ-STGPW-----LLFVCENGYGKRVPLSSFRRSRLNRVglsGYKFA-EDDRLAAvfvVGYSLAEDGEsdeqVVLVSQS 890
Cdd:PRK13979 798 IKIiSIFEFeedlsIYFFSKKGLVKKTLLNEFKGEGNSTQ---AYKFKhKEDELVN---VDIKEHEEKN----ILLITEK 867
|
890 900 910 920
....*....|....*....|....*....|....*....|....*
gi 30681440 891 GTVNRIKVRDISIQSRRARGVILMRLDHAGKIQSASLISAADEEE 935
Cdd:PRK13979 868 GMAIRFKSEAVNPMGKIASGVTGISLKDEDKVIYGSIIDENDTRK 912
|
|
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
112-803 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 581.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 112 ESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDTAVYDSLVRMAQSFSL 191
Cdd:TIGR01061 12 ESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYDAMVRMSQDWKN 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 192 RCPLIQGHGNFGSIDADPPAAMRYTECRLDPLAeAVLLSDLDQDTVDFVANFDNSQKEPAVLPARLPALLLNGASGIAVG 271
Cdd:TIGR01061 92 NWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIA-SELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLLINGATGIAAG 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 272 MATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPAPDFPTGGIIMGNLGVLDAYRTGRGRVVVRGKAEVELLdpKTKR 351
Cdd:TIGR01061 171 YATNIPPHNLNEVIDALIYRIDHPNCSVDKLMEIVKGPDFPTGGIIQGEDGISKAYETGKGKFIIRAKIEIEVN--KNGL 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 352 NAVIITEIPYQTNKATLVQKIAELVENKTLEGISDIRDESDRNGMRVVIELKRGGDPALVLNNLYRHTALQSSFSCNMVG 431
Cdd:TIGR01061 249 NQIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDESDRNGIRIIIELKKDANAEKILNFLFKHTDLQINYNFNMVA 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 432 ICDGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIELITKASSHSSATAALQSEYGL 511
Cdd:TIGR01061 329 IANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDKSDAKENLIDNFKF 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 512 SEKQAEAILEITLRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLIEQEAIELKDRFSSPRRSMLEDS-DSGDL 590
Cdd:TIGR01061 409 TENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQIIASEKARNKLLKKQLEEYKKQFAQQRRSQIEDFiNQIKI 488
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 591 EDIDVIPNEEMLMAVSEKGYVKRMKADTFNLQHRGTIGKsvgklRVDDAMSDFLVCHAHDHVLFFSDRGIVYSTRAYKIP 670
Cdd:TIGR01061 489 NESELIENEDYYVLITKAGYIKRTSNRSFASSKYTDFGS-----KDDDILFAQTIANTTDQILIFTSLGNIINIPVHKLA 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 671 ECSRNAAGTPLVQILSMSEGERVTSIVPVSEFAEDRYLLMLTV-NGCIKKVSLKLFSGIR-STGIIAIQLNSGDELKWVR 748
Cdd:TIGR01061 564 DIRWKDLGEHLSNKITFDENETIVFVGTMNEFDVDQPILVLASkLGMVKRIELTELNIKRnSKATLCIKLKDKDHLISAF 643
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*
gi 30681440 749 CCSSDDLVAMASQNGMVALSTCDGVRTLSRNTKGVTAMRLKNEDKIASMDIIPAS 803
Cdd:TIGR01061 644 LQQKDKLICLVSDLGYALVFHTNEIPVVGAKAAGVKGMKLKEDDQVKSGVIFEAN 698
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
112-556 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 564.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 112 ESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDTAVYDSLVRMAQSFSL 191
Cdd:smart00434 9 KEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIVRMAQDFSN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 192 RCPLIQGHGNFGSI-DADPPAAMRYTECRLDPLAEaVLLSDLDQDTVDFVANFDNSQKEPAVLPARLPALLLNGASGIAV 270
Cdd:smart00434 89 NYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLAR-LLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVNGSSGIAV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 271 GMATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPAPDFPTGGIIMgnlgvldayrtGRGRVVVRGKAEVElldpktK 350
Cdd:smart00434 168 GMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE------D 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 351 RNAVIITEIPYQTNKATLVQKIAELVENKTLEGISDIRDES-DRNGMRVVIELKRGGDPALVLNNLYRHTALQSSFSCNM 429
Cdd:smart00434 231 DNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQTTFSINM 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 430 VGI-CDGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQ-RKHIIEGIVVGLDNVDEVIELI-TKASSHSSATAALQ 506
Cdd:smart00434 311 LALfDNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEAeRLHILEGLFIALSIIDEIIVLIrSSKDLAKEAKEKLM 390
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 30681440 507 SEYGLSEKQAEAILEITLRRLTALERKKFTDESSSLTEQITKLEQLLSTR 556
Cdd:smart00434 391 ERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASE 440
|
|
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
106-710 |
1.24e-160 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 489.03 E-value: 1.24e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 106 LHKEATESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDTAVYDSLVRM 185
Cdd:TIGR01062 6 LGNFTEEAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYEAMVLM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 186 AQSFSLRCPLIQGHGNFGSID-ADPPAAMRYTECRLDPLAEaVLLSDLDQDTVDFVANFDNSQKEPAVLPARLPALLLNG 264
Cdd:TIGR01062 86 AQPFSYRYPLVDGQGNWGAPDdPKSFAAMRYTESRLSKISE-LLLEELGQGTVDFRPNFDGTLLEPVILPARLPNILLNG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 265 ASGIAVGMATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPAPDFPTGGIIMGNLGVLDA-YRTGRGRVVVRGKAEVE 343
Cdd:TIGR01062 165 TTGIAVGMATDIPPHNLHELADAALYLIDNPKAGLDDILNIVQGPDFPTEAEIIDKAEEIRKiYETGRGSFRMRARWKKE 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 344 LLdpktkrnAVIITEIPYQTNKATLVQKIAELVENKTLEGISDIRDESDR-NGMRVVIELK-RGGDPALVLNNLYRHTAL 421
Cdd:TIGR01062 245 DG-------QIVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDHeNPIRVVIVPRsNRVDPDIVMEHLFATTDL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 422 QSSFSCNMVGI-CDGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIELITKassHSS 500
Cdd:TIGR01062 318 EKSYRLNMNMIgLDNVPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIRE---EDE 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 501 ATAALQSEYGLSEKQAEAILEITLRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLIEQEAIELKDRFSSPRRS 580
Cdd:TIGR01062 395 PKTILMERFKLSAIQAEAILNLRLRHLAKLEEHAIIDEQSELEKERAILEKILKSERELNQLVKKEIQADATKYGLARRS 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 581 MLEDSDSGD-LEDIDVIPNEEMLMAVSEKGYVKRMKADTFNLqhrgtigkSVGKLRVDDAMSDFLVCHAHDHVLFFSDRG 659
Cdd:TIGR01062 475 SLEEREEAKqVSEIDMIPKEPVTIILSKMGWVRSAKGHDIDL--------STLKYKAGDSEKAIIEGKSNQKVVFIDSTG 546
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 30681440 660 IVYSTRAYKIPecSRNAAGTPLVQILSMSEGERVTSIVPVSefaEDRYLLM 710
Cdd:TIGR01062 547 RSYALDPDNLP--SARGQGEPLTGKLLLPIGATITNILMYS---PNQLLLM 592
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
103-554 |
2.87e-64 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 228.82 E-value: 2.87e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 103 PFELHKEATESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHElgMSSKKpYKKCARVVGEVLgKFHPHGDTAVYDSL 182
Cdd:PRK09631 1 MMDIKTLFKDNFLQYASYVIKDRAIPDVIDGLKPVQRRILHSLFE--MHDGK-FHKVANVVGNTM-KYHPHGDASIYEAL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 183 VRMAQsfslRCPLIQGHGNFGSI-DADPPAAMRYTECRLDPLAEAVLLSdldQDTVDFVANFDNSQKEPAVLPARLPALL 261
Cdd:PRK09631 77 VNLAN----KDLFIDKQGNFGNLfTGDPASAARYIECRLTPLAKEVLYN---KEITEYEPSYDGRNNEPLCLPAKIPVIL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 262 LNGASGIAVGMATNIPPHNLGELVdvlcalihnpEATLQELL--EYMPAPDFPTGGIIMGNlgvldAYRTGRGRVVVRgk 339
Cdd:PRK09631 150 IQGAEGIAVGMATKILPHNFNEIL----------QAVKSELLgeSFALYPDFPTGGIVDVS-----EYADGNGKVLVR-- 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 340 AEVELLDPKTkrnaVIITEIPYQTNKATLVQKIAELVENKTLEgISDIRDESDRNgmrVVIELK--RGGDPALVLNNLYR 417
Cdd:PRK09631 213 AKIETKDEKT----IVIREIPFGTTTESLIASIEKAARKGKIK-ISSINDYTAEN---VEIEIKlpRGVYASEVIEALYA 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 418 HTALQSSFSCNMVGICDGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQRKH--IIEGIVVGlDNVDEVIELITKA 495
Cdd:PRK09631 285 YTDCEVSISVNLLVIKDRYPVIYTVTDIIKFHAEHLQKVLKMELELERAKLLEKIFakTLEQIFIE-ERIYKRIETISSE 363
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 30681440 496 SSHSSATAALQSEYG------LSEKQAEAILEITLRRLTALERKKFTDESSSLTEQITKLEQLLS 554
Cdd:PRK09631 364 EDVISIVLSELKPFKeelsrdVTEEDIENLLKIPIRRISLFDIDKNQKEIRILNKELKSVEKNLK 428
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
114-494 |
2.72e-51 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 194.84 E-value: 2.72e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 114 YMSYALSVLLGRALPDVRDGLKPVHRRILFAMHEL--GMsskkpYKKCARVVGEVLgKFHPHGDTAVYDSLVRMAQsfsl 191
Cdd:PRK12758 31 FLDYASYVILERAVPHIEDGLKPVQRRILHSMKEMddGR-----YNKVANVVGHTM-QYHPHGDASIGDALVQLGQ---- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 192 RCPLIQGHGNFGSI-DADPPAAMRYTECRLDPLAEAVLLSDldqDTVDFVANFDNSQKEPAVLPARLPALLLNGASGIAV 270
Cdd:PRK12758 101 KDLLIDTQGNWGNIlTGDGAAAPRYIEARLSKFALEVVFNP---KTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGIAV 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 271 GMATNIPPHNLGELVDVLCALIHNPEATLqelleYmpaPDFPTGGIImgnlgvlD--AYRTGR--GRVVVRgkAEVELLD 346
Cdd:PRK12758 178 GLSTKILPHNFNELIDASIAYLKGKEFKL-----Y---PDFPTGGII-------DvsNYNDGErgGRVRVR--AKIEKLD 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 347 PKTkrnaVIITEIPYQTNKATLVQKIAELVENKTLEgISDIRDESDRNgMRVVIELKRGGDPALVLNNLYRHTALQSSFS 426
Cdd:PRK12758 241 KKT----LVITEIPYGTTTSSLIDSILKANDKGKIK-IKKVEDNTAAD-VEILVHLAPGVSPDKTIDALYAFTDCEVSIS 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 30681440 427 CNMVGICDGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQRKH--------IIEGIVVGLD---NVDEVIELITK 494
Cdd:PRK12758 315 PNACVIIDNKPHFLGVSDILRRSTDHTVSLLKQELEIRLSELEEQWHfaslekifIEERIYKEIEeaeTWEAVIEAIDK 393
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
114-447 |
1.29e-43 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 165.45 E-value: 1.29e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 114 YMSYALSVLLGRALPDVRDGLKPVHRRILFAMHElgMSSKKPYKkCARVVGEVLGkFHPHGDTAVYDSLVRMAQsfslRC 193
Cdd:PRK09630 12 FMHYASYVILERAIPHILDGLKPVQRRLLWTLFR--MDDGKMHK-VANIAGRTMA-LHPHGDAPIVEALVVLAN----KG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 194 PLIQGHGNFGS-IDADPPAAMRYTECRLDPLAEAVLLsdlDQDTVDFVANFDNSQKEPAVLPARLPALLLNGASGIAVGM 272
Cdd:PRK09630 84 YLIDTQGNFGNpLTGDPHAAARYIEARLSPLAKEVLF---NTDLMTFHDSYDGREKEPDILPAKLPLLLLHGVDGIAVGM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 273 ATNIPPHNLGELVDVLCALIHNPEATLqelleympAPDFPTGgiimgnlGVLDA--YRTGRGRVVVRgkAEVELLDPKTk 350
Cdd:PRK09630 161 TTKIFPHNFCELLEAQIAILNDQPFTL--------LPDFPSG-------GTMDAseYQDGLGSITLR--ASIDIINDKT- 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 351 rnaVIITEIPYQTNKATLVQKIaelvENKTLEG---ISDIRDESDrNGMRVVIELKRGGDPALVLNNLYRHTALQSSFSC 427
Cdd:PRK09630 223 ---LLIKEICPSTTTETLIRSI----ENAAKRGiikIDSIQDFST-DLPHIEIKLPKGIYAKDLLRPLFTHTECQVILTS 294
|
330 340
....*....|....*....|
gi 30681440 428 NMVGICDGEPKLMGLKELLQ 447
Cdd:PRK09630 295 RPTAIYQNKPVETSISEILR 314
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
117-545 |
1.93e-37 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 146.36 E-value: 1.93e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 117 YALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDTAVYDSLVRMAQSFSLRCPLI 196
Cdd:PHA02592 19 YAMYTVEERAIPNLIDGLKPVQRFVIHRALEYAKGNKEKFDKVAAIAGGVADLGYHHGETSAQDAGALMANTWNNNIPLL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 197 QGHGNFGSIDADPPAAMRYTECRLDPLAEAVLlSDLDQDTVdfvaNFDNSQKEPAVLPARLPALLLNGASGIAVGMATNI 276
Cdd:PHA02592 99 DGQGNFGSRLVQKAAAARYIFARVHDNFRKIY-KDEDLAPV----HEDPEHIPPAFYLPIIPMVLLNGVSGIATGYATNI 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 277 PPHNLGELVDVLcalihnpEATLQELLEYMPAPDFP--TGGIImgnlgvldayRTGRGRVVVRGKAEvelLDPKTKrnaV 354
Cdd:PHA02592 174 LPHSPKSVIKAV-------LAALNGKDITEPKVQFPefKGEVV----------EIEPGSYEIRGTYE---LNGKTK---L 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 355 IITEIPYQTNKATLVQKIAELVENKTLEGIsdirDESDRNGMRVVIELKRGGDPALVLNNLYRHTALQSSFSCNMVGIcD 434
Cdd:PHA02592 231 HITEIPVKYDRETYVAVLDPLEEKGKIVSY----DDCTEDGFRFKVTLKREENEEATHEKIMKDFGLIERVSQNITVI-N 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 435 GEPKLM---GLKELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNV-DEVIELitKASSHSSATAALQSEYG 510
Cdd:PHA02592 306 ENGKLKvyeNAEDLIRDFVEIRKTYVQKRIQYEIKETEEAFDLALAKAEFIKRViAGEIVL--QGKTRSELTEELSDNKD 383
|
410 420 430
....*....|....*....|....*....|....*
gi 30681440 511 LSEkQAEAILEITLRRLTALERKKFTDESSSLTEQ 545
Cdd:PHA02592 384 FGE-YADKLVAMNIYSMTSDEREKLQKEAEELEKE 417
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
125-476 |
4.14e-21 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 99.74 E-value: 4.14e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 125 RALPDVRDGLKPVHRRILFAMHelgmssKKPYK---KCARVVGEVLGK--FHpHGDTAVYDSLVRMAQSF--SLRCPLIQ 197
Cdd:PTZ00108 680 RSIPSLVDGLKPGQRKILFACF------KRNLKneiKVAQLSGYVSEHsaYH-HGEQSLQQTIVGMAQNFvgSNNINLLY 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 198 GHGNFGS-----IDAdppAAMRYTECRLDPLAEAVLLSDLDQdTVDFVaNFDNSQKEPAVLPARLPALLLNGASGIAVGM 272
Cdd:PTZ00108 753 PCGQFGSrlqggKDH---AAARYIFTKLSKITRYIFPEEDDP-ILDYL-EDDGQSVEPFYYVPIIPMVLVNGAEGIGTGF 827
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 273 ATNIPPHNLGELVDVLCALIHNpeatlQELLEYMP-APDFpTGGIIMGnlgvldayrtGRGRVVVRGKAEvelldpKTKR 351
Cdd:PTZ00108 828 STSIPNYNPLDIIDNLRRRLNG-----EEVRPLVPwYRGF-KGTIERN----------PKGKFISKGIYE------KVPD 885
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 352 NAVIITEIPYqtNKATlvQKIAELVENKTLEG---ISDIRDESDRNGMRVVIELKRGGDPALVLNNLYRHTALQSSFSC- 427
Cdd:PTZ00108 886 GTVEITELPI--GKWT--EDYKEFLESETLKEkdvIVDYRDYSTANTVHFTVKLNDGVLEQWEEEGIEKVFKLKSTISTt 961
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 30681440 428 NMVgICDGE---PKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQRKHIIE 476
Cdd:PTZ00108 962 NMV-LFDENgkiKKYSDALDILKEFYLVRLDLYKKRKEYLLGKLERELARLS 1012
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
123-481 |
3.53e-15 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 80.52 E-value: 3.53e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 123 LGRALPDVRDGLKPVHRRILFAmhelgmSSKKPYKKCARV------VGEvLGKFHpHGDTAVYDSLVRMAQSF--SLRCP 194
Cdd:PLN03128 671 LARSIPSMVDGLKPSQRKVLFA------CFKRNLKSEIKVaqlsgyVAE-HSAYH-HGEASLASTIIGMAQDFvgSNNIN 742
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 195 LIQGHGNFGS-----IDAdppAAMRYTECRLDPLAEAVLLSDlDQDTVDFVaNFDNSQKEPAVLPARLPALLLNGASGIA 269
Cdd:PLN03128 743 LLTPSGQFGTrlqggKDA---ASARYIFTRLSPITRALFPKD-DDVLLNYL-NEDGQSIEPEWYCPIIPMVLVNGSEGIG 817
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 270 VGMATNIPPHNLGELVDVLCALIHNpeatlqELLEYMpAPDFP--TGGIImgnlgvlDAYRTGRGRVVVRGKAEvelldp 347
Cdd:PLN03128 818 TGWSTFIPNYNPRDIIANIRRLLRG------EELEPM-HPWYRgfKGTIT-------EVSTSRSGSYTVTGIIE------ 877
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 348 KTKRNAVIITEIPY----QTNKATLVqkiAELVENKTLEG-ISDIRDESDRNGMRVVIELKRGGDPALVLNNLYRHTALQ 422
Cdd:PLN03128 878 QIGDTTIRITELPVrkwtQDYKEFLE---ALLTGTKKKEPeIKDFKENHTDTTVHFTVTLSEEKMARALAEGLEKKFKLS 954
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 30681440 423 SSFSCNMVGICDGEPKLMGLK---ELLQAFIDFRC-------SVVERRARFKLSHAQQRKHIIEGIVVG 481
Cdd:PLN03128 955 TTISTSNMHLFDKDGKIKKYDspeDILEEFFHLRLdlyvkrkEVLLENLEYELKKLDNKARFILAVVKG 1023
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
123-286 |
1.49e-10 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 65.65 E-value: 1.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 123 LGRALPDVRDGLKPVHRRILFAmhelgmSSKKPYKKCARV---VGEV--LGKFHpHGDTAVYDSLVRMAQSF--SLRCPL 195
Cdd:PLN03237 696 LQRSIPSMVDGLKPGQRKILFC------SFKRNFVKEAKVaqlSGYVseHSAYH-HGEQSLASTIIGMAQDFvgSNNINL 768
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 196 IQGHGNFG--SIDADPPAAMRYTECRLDPLAEAVLLSDlDQDTVDFVaNFDNSQKEPAVLPARLPALLLNGASGIAVGMA 273
Cdd:PLN03237 769 LLPNGQFGtrLQGGKDHASARYIFTRLSPITRFLFPKD-DDILLDYL-NEDGQSIEPTWYMPIIPTVLVNGAEGIGTGWS 846
|
170
....*....|...
gi 30681440 274 TNIPPHNLGELVD 286
Cdd:PLN03237 847 TFIPNYNPRDIVA 859
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
650-700 |
1.23e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 51.72 E-value: 1.23e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 30681440 650 DHVLFFSDRGIVYSTRAYKIPECSRNAAGtplVQILSMSEGERVTSIVPVS 700
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKG---VKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
754-801 |
6.94e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 49.41 E-value: 6.94e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 30681440 754 DLVAMASQNGMVALSTCDGVRTLSRNTKGVTAMRLKNEDKIASMDIIP 801
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
600-646 |
8.20e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 49.41 E-value: 8.20e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 30681440 600 EMLMAVSEKGYVKRMKADTFNLQHRGTIGKSVGKLRVDDAMSDFLVC 646
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
825-870 |
1.41e-07 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 48.64 E-value: 1.41e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 30681440 825 WLLFVCENGYGKRVPLSSFRRSRLNRVGLSGYKFAEDDRLAAVFVV 870
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
882-929 |
2.13e-06 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 45.17 E-value: 2.13e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 30681440 882 EQVVLVSQSGTVNRIKVRDISIQSRRARGVILMRLDHAGKIQSASLIS 929
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
707-751 |
3.19e-04 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 39.01 E-value: 3.19e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 30681440 707 YLLMLTVNGCIKKVSLKLFSGIR--STGIIAIQLNSGDELKWVRCCS 751
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGrgAKGVKGINLKEGDKVVSVLVVN 48
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
508-591 |
8.15e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 40.19 E-value: 8.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30681440 508 EYGLSEKqaEAILEiTLRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLIEQEAIELKDRFSSPRRSMLE-DSD 586
Cdd:pfam10174 442 EEALSEK--ERIIE-RLKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKkDSK 518
|
....*
gi 30681440 587 SGDLE 591
Cdd:pfam10174 519 LKSLE 523
|
|
| |
