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Conserved domains on  [gi|22331028|ref|NP_187874|]
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floral homeotic protein (HUA1) [Arabidopsis thaliana]

Protein Classification

zinc finger CCCH domain-containing protein( domain architecture ID 10457906)

zinc finger CCCH domain-containing protein similar to Homo sapiens proline-rich protein 3 (PRR3)

CATH:  4.10.1000.10
Gene Ontology:  GO:0046872|GO:0003676
PubMed:  12665246|27990022
SCOP:  3001741

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
421-446 2.20e-08

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 49.88  E-value: 2.20e-08
                          10        20
                  ....*....|....*....|....*.
gi 22331028   421 PGQSECDYYMKTGECKFGERCKFHHP 446
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHG 26
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
478-500 2.28e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 46.80  E-value: 2.28e-07
                          10        20
                  ....*....|....*....|...
gi 22331028   478 NCPYYMKTGTCKYGATCKFDHPP 500
Cdd:pfam00642   5 LCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
342-367 9.89e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 44.88  E-value: 9.89e-07
                          10        20
                  ....*....|....*....|....*.
gi 22331028   342 GEVDCPFYLKTGSCKYGATCRYNHPE 367
Cdd:pfam00642   2 KTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
274-295 2.14e-06

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 44.11  E-value: 2.14e-06
                          10        20
                  ....*....|....*....|..
gi 22331028   274 CTFYMKTGKCKFGLSCKFHHPK 295
Cdd:pfam00642   6 CRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
226-252 1.19e-05

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 42.18  E-value: 1.19e-05
                          10        20
                  ....*....|....*....|....*..
gi 22331028   226 PGEPDCPYYIKTQRCKYGSKCKFNHPR 252
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
176-200 1.98e-05

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 41.41  E-value: 1.98e-05
                          10        20
                  ....*....|....*....|....*
gi 22331028   176 GEKDCTHYMQTRTCKFGESCRFDHP 200
Cdd:pfam00642   2 KTELCRFFLRTGYCKYGDRCKFAHG 26
 
Name Accession Description Interval E-value
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
421-446 2.20e-08

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 49.88  E-value: 2.20e-08
                          10        20
                  ....*....|....*....|....*.
gi 22331028   421 PGQSECDYYMKTGECKFGERCKFHHP 446
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHG 26
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
478-500 2.28e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 46.80  E-value: 2.28e-07
                          10        20
                  ....*....|....*....|...
gi 22331028   478 NCPYYMKTGTCKYGATCKFDHPP 500
Cdd:pfam00642   5 LCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
342-367 9.89e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 44.88  E-value: 9.89e-07
                          10        20
                  ....*....|....*....|....*.
gi 22331028   342 GEVDCPFYLKTGSCKYGATCRYNHPE 367
Cdd:pfam00642   2 KTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
274-295 2.14e-06

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 44.11  E-value: 2.14e-06
                          10        20
                  ....*....|....*....|..
gi 22331028   274 CTFYMKTGKCKFGLSCKFHHPK 295
Cdd:pfam00642   6 CRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
226-252 1.19e-05

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 42.18  E-value: 1.19e-05
                          10        20
                  ....*....|....*....|....*..
gi 22331028   226 PGEPDCPYYIKTQRCKYGSKCKFNHPR 252
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
176-200 1.98e-05

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 41.41  E-value: 1.98e-05
                          10        20
                  ....*....|....*....|....*
gi 22331028   176 GEKDCTHYMQTRTCKFGESCRFDHP 200
Cdd:pfam00642   2 KTELCRFFLRTGYCKYGDRCKFAHG 26
ZnF_C3H1 smart00356
zinc finger;
420-446 5.53e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 37.22  E-value: 5.53e-04
                           10        20
                   ....*....|....*....|....*..
gi 22331028    420 RPGQSECDYYmKTGECKFGERCKFHHP 446
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHP 26
ZnF_C3H1 smart00356
zinc finger;
340-367 6.80e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 37.22  E-value: 6.80e-04
                           10        20
                   ....*....|....*....|....*...
gi 22331028    340 RSGEVDCPFYlKTGSCKYGATCRYNHPE 367
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
225-252 1.33e-03

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 36.07  E-value: 1.33e-03
                           10        20
                   ....*....|....*....|....*...
gi 22331028    225 RPGEPDCPYYiKTQRCKYGSKCKFNHPR 252
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
473-500 1.94e-03

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 35.68  E-value: 1.94e-03
                           10        20
                   ....*....|....*....|....*...
gi 22331028    473 REGALNCPYYmKTGTCKYGATCKFDHPP 500
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
 
Name Accession Description Interval E-value
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
421-446 2.20e-08

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 49.88  E-value: 2.20e-08
                          10        20
                  ....*....|....*....|....*.
gi 22331028   421 PGQSECDYYMKTGECKFGERCKFHHP 446
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHG 26
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
478-500 2.28e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 46.80  E-value: 2.28e-07
                          10        20
                  ....*....|....*....|...
gi 22331028   478 NCPYYMKTGTCKYGATCKFDHPP 500
Cdd:pfam00642   5 LCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
342-367 9.89e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 44.88  E-value: 9.89e-07
                          10        20
                  ....*....|....*....|....*.
gi 22331028   342 GEVDCPFYLKTGSCKYGATCRYNHPE 367
Cdd:pfam00642   2 KTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
274-295 2.14e-06

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 44.11  E-value: 2.14e-06
                          10        20
                  ....*....|....*....|..
gi 22331028   274 CTFYMKTGKCKFGLSCKFHHPK 295
Cdd:pfam00642   6 CRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
226-252 1.19e-05

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 42.18  E-value: 1.19e-05
                          10        20
                  ....*....|....*....|....*..
gi 22331028   226 PGEPDCPYYIKTQRCKYGSKCKFNHPR 252
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
176-200 1.98e-05

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 41.41  E-value: 1.98e-05
                          10        20
                  ....*....|....*....|....*
gi 22331028   176 GEKDCTHYMQTRTCKFGESCRFDHP 200
Cdd:pfam00642   2 KTELCRFFLRTGYCKYGDRCKFAHG 26
ZnF_C3H1 smart00356
zinc finger;
420-446 5.53e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 37.22  E-value: 5.53e-04
                           10        20
                   ....*....|....*....|....*..
gi 22331028    420 RPGQSECDYYmKTGECKFGERCKFHHP 446
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHP 26
ZnF_C3H1 smart00356
zinc finger;
340-367 6.80e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 37.22  E-value: 6.80e-04
                           10        20
                   ....*....|....*....|....*...
gi 22331028    340 RSGEVDCPFYlKTGSCKYGATCRYNHPE 367
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
225-252 1.33e-03

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 36.07  E-value: 1.33e-03
                           10        20
                   ....*....|....*....|....*...
gi 22331028    225 RPGEPDCPYYiKTQRCKYGSKCKFNHPR 252
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
473-500 1.94e-03

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 35.68  E-value: 1.94e-03
                           10        20
                   ....*....|....*....|....*...
gi 22331028    473 REGALNCPYYmKTGTCKYGATCKFDHPP 500
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
zf_CCCH_4 pfam18345
Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch ...
 479-498 3.24e-03

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch domain-containing proteins such as ZIP. Functional studies indicate that ZIP specifically targets EGFR and represses its transcription, and that the zinc finger and the coiled-coil domains are central to that process.


Pssm-ID: 465719 [Multi-domain]  Cd Length: 19  Bit Score: 35.09  E-value: 3.24e-03
                          10        20
                  ....*....|....*....|
gi 22331028   479 CPYYMKtGTCKYGATCKFDH 498
Cdd:pfam18345   1 CKFFLK-GRCRYGDKCRFAH 19
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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