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Conserved domains on  [gi|15228782|ref|NP_191810|]
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disulfide isomerase-like protein [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ER_PDI_fam super family cl36828
protein disulfide isomerase, eukaryotic; This model represents eukaryotic protein disulfide ...
 3-54 1.46e-13

protein disulfide isomerase, eukaryotic; This model represents eukaryotic protein disulfide isomerases retained in the endoplasmic reticulum (ER) and closely related forms. Some members have been assigned alternative or additional functions such as prolyl 4-hydroxylase and dolichyl-diphosphooligosaccharide-protein glycotransferase. Members of this family have at least two protein-disulfide domains, each similar to thioredoxin but with the redox-active disulfide in the motif PWCGHCK, and an ER retention signal at the extreme C-terminus (KDEL, HDEL, and similar motifs).


The actual alignment was detected with superfamily member TIGR01130:

Pssm-ID: 273457 [Multi-domain]  Cd Length: 462  Bit Score: 64.31  E-value: 1.46e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 15228782     3 MNMVEVEVDQIESWVKDFQDGKAAVHKNSQPIPAENNEPVKLVVAESLDDIV 54
Cdd:TIGR01130 309 MDQEEFSSENLEAFVKDFLDGKLKPYLKSEPIPEDDEGPVKVLVGKNFDEIV 360
 
Name Accession Description Interval E-value
ER_PDI_fam TIGR01130
protein disulfide isomerase, eukaryotic; This model represents eukaryotic protein disulfide ...
 3-54 1.46e-13

protein disulfide isomerase, eukaryotic; This model represents eukaryotic protein disulfide isomerases retained in the endoplasmic reticulum (ER) and closely related forms. Some members have been assigned alternative or additional functions such as prolyl 4-hydroxylase and dolichyl-diphosphooligosaccharide-protein glycotransferase. Members of this family have at least two protein-disulfide domains, each similar to thioredoxin but with the redox-active disulfide in the motif PWCGHCK, and an ER retention signal at the extreme C-terminus (KDEL, HDEL, and similar motifs).


Pssm-ID: 273457 [Multi-domain]  Cd Length: 462  Bit Score: 64.31  E-value: 1.46e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 15228782     3 MNMVEVEVDQIESWVKDFQDGKAAVHKNSQPIPAENNEPVKLVVAESLDDIV 54
Cdd:TIGR01130 309 MDQEEFSSENLEAFVKDFLDGKLKPYLKSEPIPEDDEGPVKVLVGKNFDEIV 360
PTZ00102 PTZ00102
disulphide isomerase; Provisional
 10-59 1.04e-05

disulphide isomerase; Provisional


Pssm-ID: 240266 [Multi-domain]  Cd Length: 477  Bit Score: 42.05  E-value: 1.04e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 15228782   10 VDQIESWVKDFQDGKAAVHKNSQPIPAENNEPVKLVVAESLDDIVQVSER 59
Cdd:PTZ00102 327 VEALIEFFKDVEAGKVEKSIKSEPIPEEQDGPVKVVVGNTFEEIVFKSDK 376
 
Name Accession Description Interval E-value
ER_PDI_fam TIGR01130
protein disulfide isomerase, eukaryotic; This model represents eukaryotic protein disulfide ...
 3-54 1.46e-13

protein disulfide isomerase, eukaryotic; This model represents eukaryotic protein disulfide isomerases retained in the endoplasmic reticulum (ER) and closely related forms. Some members have been assigned alternative or additional functions such as prolyl 4-hydroxylase and dolichyl-diphosphooligosaccharide-protein glycotransferase. Members of this family have at least two protein-disulfide domains, each similar to thioredoxin but with the redox-active disulfide in the motif PWCGHCK, and an ER retention signal at the extreme C-terminus (KDEL, HDEL, and similar motifs).


Pssm-ID: 273457 [Multi-domain]  Cd Length: 462  Bit Score: 64.31  E-value: 1.46e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 15228782     3 MNMVEVEVDQIESWVKDFQDGKAAVHKNSQPIPAENNEPVKLVVAESLDDIV 54
Cdd:TIGR01130 309 MDQEEFSSENLEAFVKDFLDGKLKPYLKSEPIPEDDEGPVKVLVGKNFDEIV 360
PTZ00102 PTZ00102
disulphide isomerase; Provisional
 10-59 1.04e-05

disulphide isomerase; Provisional


Pssm-ID: 240266 [Multi-domain]  Cd Length: 477  Bit Score: 42.05  E-value: 1.04e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 15228782   10 VDQIESWVKDFQDGKAAVHKNSQPIPAENNEPVKLVVAESLDDIVQVSER 59
Cdd:PTZ00102 327 VEALIEFFKDVEAGKVEKSIKSEPIPEEQDGPVKVVVGNTFEEIVFKSDK 376
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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