|
Name |
Accession |
Description |
Interval |
E-value |
| COG5406 |
COG5406 |
Nucleosome binding factor SPN, SPT16 subunit [Transcription, Replication, recombination and ... |
24-1027 |
0e+00 |
|
Nucleosome binding factor SPN, SPT16 subunit [Transcription, Replication, recombination and repair, Chromatin structure and dynamics];
Pssm-ID: 227693 [Multi-domain] Cd Length: 1001 Bit Score: 649.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 24 YSIDVKNFISRARALYEHWKKHSadlwGSADALAIATPPASDDLRYLKSSALNIWLLGYEFPDTIMVFTKKQIHFLCSRN 103
Cdd:COG5406 4 IRIDEERFEKRSRDLRKHLNEED----GGPDSLLVMLGKSQDVNPYQKNTALHIWLLGYEFPETLIILDDVCTAITTSKK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 104 KASLLEVvkkpAHDELKLDVIMHVKpkgDDGTGLMDAIFRAIRDLSRGDGNDSQVVGHIAREAPEGKLLETWTERLKNAN 183
Cdd:COG5406 80 KAILLQK----GLAETSLNIVVRNK---DNRTKNMEENKKLFKGSIYVIGSENKIVGDFCKDVLQGKFINEWDSIFEPVK 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 184 FQF--VDITGGLSDLFAVKDDTEVMSVKkAAYLAYSVMKNVVVPNLESAIDEEKDVTHSALMDLTEKAILE---PTKASV 258
Cdd:COG5406 153 SEFnaSDVSLGLSKMFLTKDAEEIANCR-ASSAASSVLMRYFVKEMEMLWDGAFKITHGKLSDLMESLIDDvefFQTKSL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 259 KLKPENVDI---CYPPIFQSGGKFDLKPSAASNDELLTYDpasIIICAVGARYNSYCSNVARTYLIDATSLQSKAYEVLL 335
Cdd:COG5406 232 KLGDIDLDQlewCYTPIIQSGGSIDLTPSAFSFPMELTGD---VVLLSIGIRYNGYCSNMSRTILTDPDSEQQKNYEFLY 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 336 KAHEAAIDALRSGRKINTVYQAALSVVEKNAPEFVDKLTKSAGTGIGLEFRESGLNINAKNDKVLRPKMAFNVSLGFQNL 415
Cdd:COG5406 309 MLQKYILGLVRPGTDSGIIYSEAEKYISSNGPELGPNFIYNVGLMIGIEFRSSQKPFNVKNGRVLQAGCIFNISLGFGNL 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 416 EcesESRSKNKkFSLLLADTVLVTDQKPELLTKCSKSVKDVAYSFKEDEEEEK---PRKKARTSGSENY-ITKTALRSD- 490
Cdd:COG5406 389 I---NPHPKNN-YALLLIDTEQISLSNPIVFTDSPKAQGDISFLFGEDDETPEyltLQDKAPDFLDKTIsSHRSKFRDEt 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 491 -DHVVSKEELRKQHQAELARQKNEETARRLAgDSSGAGDSRSTAKTSADVVAYKNVNDMPH--KELMIQVDTRNEAVLLP 567
Cdd:COG5406 465 rEHELNARKKRVEHQKELLDKIIEEGLERFR-NASDAGPDSIEEKSEKRIESYSRDSQLPRqiGELRIIVDFARQSIILP 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 568 IYGSLVPFHVATIRTVSGNQDTNRNcYIRIIFNVPGTPFNPHDSNSLKNQGAIYLKEVSFRTKDSRHSSEVTQQIKTLRR 647
Cdd:COG5406 544 IGGRPVPFHISSIKNASKNDEGNFV-YLRLNFKSPGKGGGKTEELPCEQRGEQFLRSITSRSIRGNRMSDLFKEINDLKK 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 648 QVMARESERAERATLVTQEKLQLAGNKfKPLRLSELWIRPPFSGrKKIPGTLEAHANGFRY-STTRPDERVDVLFANIKH 726
Cdd:COG5406 623 GATKRETERKEDADVLEQDKLIERKLS-RTDVYMKTDVRPGSDG-KRKPGNLEIHENGIRFqSPLRSDSHIDILFSNIKH 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 727 AFFQPAEKEMITLLHFHLHNHIMVGTKKTKDVQFYVEVMD--VVQSLGGGRRSAY-DPDEIDEEQRERDRKNKINMDFNH 803
Cdd:COG5406 701 LFFQECNGELIVIIHFHLKSPILTGKRKVQDVQFYREASDtmVDETGKRGRKEHYgDEDELEQEQEERRRRAALDQEFKS 780
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 804 FANRVNDMwqlpqfASLDLEFDQPLRELGFHGVPHKTSAFIIPTSSCLVELIEYPFLVVSLSEIEIVNLERVGFGQKNFD 883
Cdd:COG5406 781 FASSIAEA------SEGRIEFKVQFRKLGFYGVPFRSSVMIKPTTDCLVQLDEAPFFVITLEEVEIVNLERVQFGLKNFD 854
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 884 MAIIFKDFKKDVLRVDSVPTSSLEGIKEWLDTTDIKYYESKLNLNWRQILKTITDDPQSFIDDGGWEFLNLdGSDSESGG 963
Cdd:COG5406 855 VVFILRDFYRPLVHINTVPVESLDKLKEWLDSNDILFMETSANLNWNTIMKSIMKDPISFFEDGGWSFLMV-GSDDESDE 933
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15236899 964 SEESDKGYEpsDVEVESESEDEASESESLVESDDDEEEDSEQESEEEKGKTWDELEREATNADR 1027
Cdd:COG5406 934 SEEEVSEYE--ASSDDESDETDEDEESDESSEDLSEDESENDSSDEEDGEDWDELESKAAYDSR 995
|
|
| CDC68-like |
cd01091 |
Related to aminopeptidase P and aminopeptidase M, a member of this domain family is present in ... |
208-448 |
1.85e-93 |
|
Related to aminopeptidase P and aminopeptidase M, a member of this domain family is present in cell division control protein 68, a transcription factor.
Pssm-ID: 238524 [Multi-domain] Cd Length: 243 Bit Score: 297.72 E-value: 1.85e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 208 VKKAAYLAYSVMKNVVVPNLESAIDEEKDVTHSALMDLTEKAILEPTKASVKLKPENVDICYPPIFQSGGKFDLKPSAAS 287
Cdd:cd01091 4 IKKASDATVDVLKKFFVDEVEEIIDQEKKVTHSKLSDKVEKAIEDKKKYKAKLDPEQLDWCYPPIIQSGGNYDLLKSSSS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 288 NDELLtYDPASIIiCAVGARYNSYCSNVARTYLIDATSLQSKAYEVLLKAHEAAIDALRSGRKINTVYQAALSVVEKNAP 367
Cdd:cd01091 84 SDKLL-YHFGVII-CSLGARYKSYCSNIARTFLIDPTSEQQKNYNFLLALQEEILKELKPGAKLSDVYQKTLDYIKKKKP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 368 EFVDKLTKSAGTGIGLEFRESGLNINAKNDKVLRPKMAFNVSLGFQNLECESESRSKNKKFSLLLADTVLVTDQKP-ELL 446
Cdd:cd01091 162 ELEPNFTKNLGFGIGLEFRESSLIINAKNDRKLKKGMVFNLSIGFSNLQNPEPKDKESKTYALLLSDTILVTEDEPaIVL 241
|
..
gi 15236899 447 TK 448
Cdd:cd01091 242 TN 243
|
|
| SPT16 |
pfam08644 |
FACT complex subunit (SPT16/CDC68); Proteins in this family are subunits the FACT complex. The ... |
555-708 |
2.35e-71 |
|
FACT complex subunit (SPT16/CDC68); Proteins in this family are subunits the FACT complex. The FACT complex plays a role in transcription initiation and promotes binding of TATA-binding protein (TBP) to a TATA box in chromatin.
Pssm-ID: 462545 Cd Length: 151 Bit Score: 233.60 E-value: 2.35e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 555 IQVDTRNEAVLLPIYGSLVPFHVATIRTVSGNQDTNRnCYIRIIFNVPGTPFNPHDSNSLKNQGAIYLKEVSFRTKDSRH 634
Cdd:pfam08644 1 IYVDKKNETILLPIYGRPVPFHISTIKNVSKSDEGNY-TYLRINFNTPGSGTGKKDDLPFEDPDAIFIKELTFRSKDSKH 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15236899 635 SSEVTQQIKTLRRQVMARESERAERATLVTQEKLQLAGNKFKPlRLSELWIRPPFSGrKKIPGTLEAHANGFRY 708
Cdd:pfam08644 80 LQDVFKQIKELKKRVKKREAERKERADLVEQEKLILSKNRRPP-RLPDVFIRPTIDG-KRVPGTLEAHTNGLRY 151
|
|
| PRK09795 |
PRK09795 |
aminopeptidase; Provisional |
305-453 |
2.17e-08 |
|
aminopeptidase; Provisional
Pssm-ID: 182080 [Multi-domain] Cd Length: 361 Bit Score: 57.64 E-value: 2.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 305 GARYNSYCSNVARTYLIDATSLQSKA------YEVLLKAHEAAIDALRSGRKINTVYQAALSVVEKNApeFVDKLTKSAG 378
Cdd:PRK09795 214 GALYQGYCSDMTRTLLVNGEGVSAEShplfnvYQIVLQAQLAAISAIRPGVRCQQVDDAARRVITEAG--YGDYFGHNTG 291
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15236899 379 TGIGLEFRESGlNINAKNDKVLRPKMAFNVSLGFQnlecesesrsKNKKFSLLLADTVLVTDQKPELLTKCSKSV 453
Cdd:PRK09795 292 HAIGIEVHEDP-RFSPRDTTTLQPGMLLTVEPGIY----------LPGQGGVRIEDVVLVTPQGAEVLYAMPKTV 355
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COG5406 |
COG5406 |
Nucleosome binding factor SPN, SPT16 subunit [Transcription, Replication, recombination and ... |
24-1027 |
0e+00 |
|
Nucleosome binding factor SPN, SPT16 subunit [Transcription, Replication, recombination and repair, Chromatin structure and dynamics];
Pssm-ID: 227693 [Multi-domain] Cd Length: 1001 Bit Score: 649.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 24 YSIDVKNFISRARALYEHWKKHSadlwGSADALAIATPPASDDLRYLKSSALNIWLLGYEFPDTIMVFTKKQIHFLCSRN 103
Cdd:COG5406 4 IRIDEERFEKRSRDLRKHLNEED----GGPDSLLVMLGKSQDVNPYQKNTALHIWLLGYEFPETLIILDDVCTAITTSKK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 104 KASLLEVvkkpAHDELKLDVIMHVKpkgDDGTGLMDAIFRAIRDLSRGDGNDSQVVGHIAREAPEGKLLETWTERLKNAN 183
Cdd:COG5406 80 KAILLQK----GLAETSLNIVVRNK---DNRTKNMEENKKLFKGSIYVIGSENKIVGDFCKDVLQGKFINEWDSIFEPVK 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 184 FQF--VDITGGLSDLFAVKDDTEVMSVKkAAYLAYSVMKNVVVPNLESAIDEEKDVTHSALMDLTEKAILE---PTKASV 258
Cdd:COG5406 153 SEFnaSDVSLGLSKMFLTKDAEEIANCR-ASSAASSVLMRYFVKEMEMLWDGAFKITHGKLSDLMESLIDDvefFQTKSL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 259 KLKPENVDI---CYPPIFQSGGKFDLKPSAASNDELLTYDpasIIICAVGARYNSYCSNVARTYLIDATSLQSKAYEVLL 335
Cdd:COG5406 232 KLGDIDLDQlewCYTPIIQSGGSIDLTPSAFSFPMELTGD---VVLLSIGIRYNGYCSNMSRTILTDPDSEQQKNYEFLY 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 336 KAHEAAIDALRSGRKINTVYQAALSVVEKNAPEFVDKLTKSAGTGIGLEFRESGLNINAKNDKVLRPKMAFNVSLGFQNL 415
Cdd:COG5406 309 MLQKYILGLVRPGTDSGIIYSEAEKYISSNGPELGPNFIYNVGLMIGIEFRSSQKPFNVKNGRVLQAGCIFNISLGFGNL 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 416 EcesESRSKNKkFSLLLADTVLVTDQKPELLTKCSKSVKDVAYSFKEDEEEEK---PRKKARTSGSENY-ITKTALRSD- 490
Cdd:COG5406 389 I---NPHPKNN-YALLLIDTEQISLSNPIVFTDSPKAQGDISFLFGEDDETPEyltLQDKAPDFLDKTIsSHRSKFRDEt 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 491 -DHVVSKEELRKQHQAELARQKNEETARRLAgDSSGAGDSRSTAKTSADVVAYKNVNDMPH--KELMIQVDTRNEAVLLP 567
Cdd:COG5406 465 rEHELNARKKRVEHQKELLDKIIEEGLERFR-NASDAGPDSIEEKSEKRIESYSRDSQLPRqiGELRIIVDFARQSIILP 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 568 IYGSLVPFHVATIRTVSGNQDTNRNcYIRIIFNVPGTPFNPHDSNSLKNQGAIYLKEVSFRTKDSRHSSEVTQQIKTLRR 647
Cdd:COG5406 544 IGGRPVPFHISSIKNASKNDEGNFV-YLRLNFKSPGKGGGKTEELPCEQRGEQFLRSITSRSIRGNRMSDLFKEINDLKK 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 648 QVMARESERAERATLVTQEKLQLAGNKfKPLRLSELWIRPPFSGrKKIPGTLEAHANGFRY-STTRPDERVDVLFANIKH 726
Cdd:COG5406 623 GATKRETERKEDADVLEQDKLIERKLS-RTDVYMKTDVRPGSDG-KRKPGNLEIHENGIRFqSPLRSDSHIDILFSNIKH 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 727 AFFQPAEKEMITLLHFHLHNHIMVGTKKTKDVQFYVEVMD--VVQSLGGGRRSAY-DPDEIDEEQRERDRKNKINMDFNH 803
Cdd:COG5406 701 LFFQECNGELIVIIHFHLKSPILTGKRKVQDVQFYREASDtmVDETGKRGRKEHYgDEDELEQEQEERRRRAALDQEFKS 780
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 804 FANRVNDMwqlpqfASLDLEFDQPLRELGFHGVPHKTSAFIIPTSSCLVELIEYPFLVVSLSEIEIVNLERVGFGQKNFD 883
Cdd:COG5406 781 FASSIAEA------SEGRIEFKVQFRKLGFYGVPFRSSVMIKPTTDCLVQLDEAPFFVITLEEVEIVNLERVQFGLKNFD 854
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 884 MAIIFKDFKKDVLRVDSVPTSSLEGIKEWLDTTDIKYYESKLNLNWRQILKTITDDPQSFIDDGGWEFLNLdGSDSESGG 963
Cdd:COG5406 855 VVFILRDFYRPLVHINTVPVESLDKLKEWLDSNDILFMETSANLNWNTIMKSIMKDPISFFEDGGWSFLMV-GSDDESDE 933
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15236899 964 SEESDKGYEpsDVEVESESEDEASESESLVESDDDEEEDSEQESEEEKGKTWDELEREATNADR 1027
Cdd:COG5406 934 SEEEVSEYE--ASSDDESDETDEDEESDESSEDLSEDESENDSSDEEDGEDWDELESKAAYDSR 995
|
|
| CDC68-like |
cd01091 |
Related to aminopeptidase P and aminopeptidase M, a member of this domain family is present in ... |
208-448 |
1.85e-93 |
|
Related to aminopeptidase P and aminopeptidase M, a member of this domain family is present in cell division control protein 68, a transcription factor.
Pssm-ID: 238524 [Multi-domain] Cd Length: 243 Bit Score: 297.72 E-value: 1.85e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 208 VKKAAYLAYSVMKNVVVPNLESAIDEEKDVTHSALMDLTEKAILEPTKASVKLKPENVDICYPPIFQSGGKFDLKPSAAS 287
Cdd:cd01091 4 IKKASDATVDVLKKFFVDEVEEIIDQEKKVTHSKLSDKVEKAIEDKKKYKAKLDPEQLDWCYPPIIQSGGNYDLLKSSSS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 288 NDELLtYDPASIIiCAVGARYNSYCSNVARTYLIDATSLQSKAYEVLLKAHEAAIDALRSGRKINTVYQAALSVVEKNAP 367
Cdd:cd01091 84 SDKLL-YHFGVII-CSLGARYKSYCSNIARTFLIDPTSEQQKNYNFLLALQEEILKELKPGAKLSDVYQKTLDYIKKKKP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 368 EFVDKLTKSAGTGIGLEFRESGLNINAKNDKVLRPKMAFNVSLGFQNLECESESRSKNKKFSLLLADTVLVTDQKP-ELL 446
Cdd:cd01091 162 ELEPNFTKNLGFGIGLEFRESSLIINAKNDRKLKKGMVFNLSIGFSNLQNPEPKDKESKTYALLLSDTILVTEDEPaIVL 241
|
..
gi 15236899 447 TK 448
Cdd:cd01091 242 TN 243
|
|
| SPT16 |
pfam08644 |
FACT complex subunit (SPT16/CDC68); Proteins in this family are subunits the FACT complex. The ... |
555-708 |
2.35e-71 |
|
FACT complex subunit (SPT16/CDC68); Proteins in this family are subunits the FACT complex. The FACT complex plays a role in transcription initiation and promotes binding of TATA-binding protein (TBP) to a TATA box in chromatin.
Pssm-ID: 462545 Cd Length: 151 Bit Score: 233.60 E-value: 2.35e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 555 IQVDTRNEAVLLPIYGSLVPFHVATIRTVSGNQDTNRnCYIRIIFNVPGTPFNPHDSNSLKNQGAIYLKEVSFRTKDSRH 634
Cdd:pfam08644 1 IYVDKKNETILLPIYGRPVPFHISTIKNVSKSDEGNY-TYLRINFNTPGSGTGKKDDLPFEDPDAIFIKELTFRSKDSKH 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15236899 635 SSEVTQQIKTLRRQVMARESERAERATLVTQEKLQLAGNKFKPlRLSELWIRPPFSGrKKIPGTLEAHANGFRY 708
Cdd:pfam08644 80 LQDVFKQIKELKKRVKKREAERKERADLVEQEKLILSKNRRPP-RLPDVFIRPTIDG-KRVPGTLEAHTNGLRY 151
|
|
| FACT-Spt16_Nlob |
pfam14826 |
FACT complex subunit SPT16 N-terminal lobe domain; The FACT or facilitator of chromatin ... |
26-192 |
2.06e-62 |
|
FACT complex subunit SPT16 N-terminal lobe domain; The FACT or facilitator of chromatin transcription complex binds to and alters the properties of nucleosomes. This family represents the N-terminal lobe of the NTD, or N-terminal domain, and acts as a protein-protein interaction domain presumably with partners outside of the FACT complex. Knockout of the whole NTD domain, 1-450 residues in UniProt:P32558, in yeast serves to tender the cells sensitive to DNA replication stress but is not lethal. The C-terminal half of NTD is structurally similar to aminopeptidases, and the most highly conserved surface residues line a cleft equivalent to the aminopeptidase substrate-binding site, family peptidase_M24, pfam00557.
Pssm-ID: 464338 Cd Length: 160 Bit Score: 208.94 E-value: 2.06e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 26 IDVKNFISRARALYEHWKKHSADLWGSADALAIATPPASDDLRYLKSSALNIWLLGYEFPDTIMVFTKKQIHFLCSRNKA 105
Cdd:pfam14826 1 IDKKLFHKRLKRLYSAWKENSADLWSGADALLIAVGKSDEDNPYQKSTALQTWLLGYEFPDTLMLFTKDKIYILTSAKKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 106 SLLEVVKKPAHDElKLDVIMHVKPK-GDDGTGLMDAIFRAIRDlsrgdgnDSQVVGHIAREAPEGKLLETWTERLKNANF 184
Cdd:pfam14826 81 KFLEPLKEGKKEE-GVPVELLVRNKdADENKKNFEKLIEAIKA-------AGKKVGVLAKDKFEGKFVDEWKKALKEAGK 152
|
....*...
gi 15236899 185 QFVDITGG 192
Cdd:pfam14826 153 EEVDVSLG 160
|
|
| Peptidase_M24 |
pfam00557 |
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ... |
266-440 |
2.18e-27 |
|
Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Pssm-ID: 459852 [Multi-domain] Cd Length: 208 Bit Score: 110.79 E-value: 2.18e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 266 DICYPPIFQSGGKFDLKPSAASNDELltyDPASIIICAVGARYNS-YCSNVARTYLI-DATSLQSKAYEVLLKAHEAAID 343
Cdd:pfam00557 46 GPAFPPIVASGPNAAIPHYIPNDRVL---KPGDLVLIDVGAEYDGgYCSDITRTFVVgKPSPEQRELYEAVLEAQEAAIA 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 344 ALRSGRKINTVYQAALSVVEKNapEFVDKLTKSAGTGIGLEFRESGLNINAKNDKVLRPKMAFNVSLGFQNLEcesesrs 423
Cdd:pfam00557 123 AVKPGVTGGDVDAAAREVLEEA--GLGEYFPHGLGHGIGLEVHEGPYISRGGDDRVLEPGMVFTIEPGIYFIP------- 193
|
170
....*....|....*..
gi 15236899 424 knKKFSLLLADTVLVTD 440
Cdd:pfam00557 194 --GWGGVRIEDTVLVTE 208
|
|
| Rtt106 |
pfam08512 |
Histone chaperone Rttp106-like; This family includes Rttp106, a histone chaperone involved in ... |
834-915 |
2.12e-22 |
|
Histone chaperone Rttp106-like; This family includes Rttp106, a histone chaperone involved in heterochromatin-mediated silencing. This domain belongs to the Pleckstrin homology domain superfamily.
Pssm-ID: 462500 Cd Length: 84 Bit Score: 92.11 E-value: 2.12e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 834 HGVPHKTSA---FIIPTSSCLVELIEYPFLVVSLSEIEIVNLERVGFGQKNFDMAIIFKdfKKDVLRVDSVPTSSLEGIK 910
Cdd:pfam08512 1 PGVKCSRKAkegYLYPLEKCLLFGFKKPPLVIPLSDIESVSFERVSFTLRTFDLVIVLK--KDPEYEFSMIDQEELDGIK 78
|
....*
gi 15236899 911 EWLDT 915
Cdd:pfam08512 79 DFLKS 83
|
|
| PepP |
COG0006 |
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; |
185-456 |
7.09e-22 |
|
Xaa-Pro aminopeptidase [Amino acid transport and metabolism];
Pssm-ID: 439777 [Multi-domain] Cd Length: 299 Bit Score: 97.20 E-value: 7.09e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 185 QFVDITGGLSDLFAVKDDTEVMSVKKAAYLAYSVMKnVVVPNLESAIDEeKDVtHSALMDLTEKAILEptkasvklkpen 264
Cdd:COG0006 59 ELVDASDLLEELRAIKSPEEIELMRKAARIADAAHE-AALAALRPGVTE-REV-AAELEAAMRRRGAE------------ 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 265 vDICYPPIFQSGGKFDLKPSAASNDELLTYDPASIIIcavGARYNSYCSNVARTYLI-DATSLQSKAYEVLLKAHEAAID 343
Cdd:COG0006 124 -GPSFDTIVASGENAAIPHYTPTDRPLKPGDLVLIDA---GAEYDGYTSDITRTVAVgEPSDEQREIYEAVLEAQEAAIA 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 344 ALRSGRKINTVYQAALSVVEKN--APEFVdkltksAGTG--IGLEFRESGlNINAKNDKVLRPKMAFNV--SLGFQN--- 414
Cdd:COG0006 200 ALKPGVTGGEVDAAARDVLAEAgyGEYFP------HGTGhgVGLDVHEGP-QISPGNDRPLEPGMVFTIepGIYIPGigg 272
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 15236899 415 --LEcesesrsknkkfslllaDTVLVTDQKPELLTKCSKSVKDV 456
Cdd:COG0006 273 vrIE-----------------DTVLVTEDGAEVLTRLPRELLEL 299
|
|
| APP_MetAP |
cd01066 |
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as ... |
208-443 |
2.50e-18 |
|
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity compared to other metallo-aminopeptidases, suggesting they play roles in regulation of biological processes rather than general protein degradation.
Pssm-ID: 238514 [Multi-domain] Cd Length: 207 Bit Score: 84.81 E-value: 2.50e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 208 VKKAAYLAYSVMKNVVvPNLESAIdEEKDVTHsALMDLTEKAILEPTkasvklkpenvdicYPPIFQSGGKFDLKPSAAS 287
Cdd:cd01066 4 LRKAAEIAEAAMAAAA-EAIRPGV-TEAEVAA-AIEQALRAAGGYPA--------------GPTIVGSGARTALPHYRPD 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 288 NDELLTYDpasIIICAVGARYNSYCSNVARTYLIDATSL-QSKAYEVLLKAHEAAIDALRSGRKINTVYQAALSVVEKNA 366
Cdd:cd01066 67 DRRLQEGD---LVLVDLGGVYDGYHADLTRTFVIGEPSDeQRELYEAVREAQEAALAALRPGVTAEEVDAAAREVLEEHG 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15236899 367 PEfvDKLTKSAGTGIGLEFRESGLnINAKNDKVLRPKMAFNVSLGFqnleCESESrsknkkFSLLLADTVLVTDQKP 443
Cdd:cd01066 144 LG--PNFGHRTGHGIGLEIHEPPV-LKAGDDTVLEPGMVFAVEPGL----YLPGG------GGVRIEDTVLVTEDGP 207
|
|
| APP-like |
cd01092 |
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse ... |
270-408 |
1.18e-13 |
|
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline.
Pssm-ID: 238525 [Multi-domain] Cd Length: 208 Bit Score: 71.00 E-value: 1.18e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 270 PPIFQSGGKFDLkPSA-ASNDELltyDPASIIICAVGARYNSYCSNVARTYLI-DATSLQSKAYEVLLKAHEAAIDALRS 347
Cdd:cd01092 50 DTIVASGPNSAL-PHGvPSDRKI---EEGDLVLIDFGAIYDGYCSDITRTVAVgEPSDELKEIYEIVLEAQQAAIKAVKP 125
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15236899 348 GRKINTVYQAALSVVEKNapEFVDKLTKSAGTGIGLEFRESGlNINAKNDKVLRPKMAFNV 408
Cdd:cd01092 126 GVTAKEVDKAARDVIEEA--GYGEYFIHRTGHGVGLEVHEAP-YISPGSDDVLEEGMVFTI 183
|
|
| PRK09795 |
PRK09795 |
aminopeptidase; Provisional |
305-453 |
2.17e-08 |
|
aminopeptidase; Provisional
Pssm-ID: 182080 [Multi-domain] Cd Length: 361 Bit Score: 57.64 E-value: 2.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 305 GARYNSYCSNVARTYLIDATSLQSKA------YEVLLKAHEAAIDALRSGRKINTVYQAALSVVEKNApeFVDKLTKSAG 378
Cdd:PRK09795 214 GALYQGYCSDMTRTLLVNGEGVSAEShplfnvYQIVLQAQLAAISAIRPGVRCQQVDDAARRVITEAG--YGDYFGHNTG 291
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15236899 379 TGIGLEFRESGlNINAKNDKVLRPKMAFNVSLGFQnlecesesrsKNKKFSLLLADTVLVTDQKPELLTKCSKSV 453
Cdd:PRK09795 292 HAIGIEVHEDP-RFSPRDTTTLQPGMLLTVEPGIY----------LPGQGGVRIEDVVLVTPQGAEVLYAMPKTV 355
|
|
| MetAP1 |
cd01086 |
Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and ... |
304-448 |
2.39e-07 |
|
Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
Pssm-ID: 238519 [Multi-domain] Cd Length: 238 Bit Score: 52.88 E-value: 2.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 304 VGARYNSYCSNVARTYLI-DATSLQSKAYEVLLKAHEAAIDALRSGRKINTVYQAALSVVEKN----APEFVdkltksaG 378
Cdd:cd01086 86 VGVELDGYHGDSARTFIVgEVSEEAKKLVEVTEEALYKGIEAVKPGNRIGDIGHAIEKYAEKNgysvVREFG-------G 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 379 TGIGLEFRESGLNIN---AKNDKVLRPKMAFN----VSLG---FQNLECESESRSKNKKFSLLLADTVLVTDQKPELLTK 448
Cdd:cd01086 159 HGIGRKFHEEPQIPNygrPGTGPKLKPGMVFTiepmINLGtyeVVTLPDGWTVVTKDGSLSAQFEHTVLITEDGPEILTL 238
|
|
| Prolidase |
cd01087 |
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline ... |
305-448 |
6.32e-07 |
|
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.
Pssm-ID: 238520 [Multi-domain] Cd Length: 243 Bit Score: 51.80 E-value: 6.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 305 GARYNSYCSNVARTYLIDA--TSLQSKAYEVLLKAHEAAIDALRSGRKINTVYQAALSV----------VEKNAPEFVDK 372
Cdd:cd01087 81 GAEYGGYASDITRTFPVNGkfTDEQRELYEAVLAAQKAAIAACKPGVSYEDIHLLAHRVlaeglkelgiLKGDVDEIVES 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 373 LTKSA----GTG--IGLEFRESGLNINAKN-DKVLRPKMAFNVSLG--FQNLECESEsrsknKKFSLL---LADTVLVTD 440
Cdd:cd01087 161 GAYAKffphGLGhyLGLDVHDVGGYLRYLRrARPLEPGMVITIEPGiyFIPDLLDVP-----EYFRGGgirIEDDVLVTE 235
|
....*...
gi 15236899 441 QKPELLTK 448
Cdd:cd01087 236 DGPENLTR 243
|
|
| PRK12896 |
PRK12896 |
methionine aminopeptidase; Reviewed |
304-447 |
1.02e-03 |
|
methionine aminopeptidase; Reviewed
Pssm-ID: 237252 [Multi-domain] Cd Length: 255 Bit Score: 42.13 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236899 304 VGARYNSYCSNVARTYLIDATSLQ-SKAYEVLLKAHEAAIDALRSGRKINTVYQAALSVVEKNAPEFVDKLTksaGTGIG 382
Cdd:PRK12896 101 VSAYLDGYHGDTGITFAVGPVSEEaEKLCRVAEEALWAGIKQVKAGRPLNDIGRAIEDFAKKNGYSVVRDLT---GHGVG 177
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15236899 383 LEFRESGLNINAKNDK----VLRPKMAFNV----SLGfqNLECESES-----RSKNKKFSLLLADTVLVTDQKPELLT 447
Cdd:PRK12896 178 RSLHEEPSVILTYTDPlpnrLLRPGMTLAVepflNLG--AKDAETLDdgwtvVTPDKSLSAQFEHTVVVTRDGPEILT 253
|
|
| |
