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Conserved domains on  [gi|15236297|ref|NP_193084|]
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myb domain protein 79 [Arabidopsis thaliana]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 999994)

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN03091 super family cl33633
hypothetical protein; Provisional
 7-111 2.77e-49

hypothetical protein; Provisional


The actual alignment was detected with superfamily member PLN03091:

Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 168.23  E-value: 2.77e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236297    7 RKGPWTAEEDRLLIEYVRVHGEGRWNSVSKLAGLKRNGKSCRLRWVNYLRPDLKRGQITPHEESIILELHAKWGNRWSTI 86
Cdd:PLN03091  13 RKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGLQRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGNRWSQI 92

                         90       100
                 ....*....|....*....|....*
gi 15236297   87 ARSLPGRTDNEIKNYWRTHFKKKAK 111
Cdd:PLN03091  93 AAQLPGRTDNEIKNLWNSCLKKKLR 117
 
Name Accession Description Interval E-value
PLN03091 PLN03091
hypothetical protein; Provisional
 7-111 2.77e-49

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 168.23  E-value: 2.77e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236297    7 RKGPWTAEEDRLLIEYVRVHGEGRWNSVSKLAGLKRNGKSCRLRWVNYLRPDLKRGQITPHEESIILELHAKWGNRWSTI 86
Cdd:PLN03091  13 RKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGLQRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGNRWSQI 92

                         90       100
                 ....*....|....*....|....*
gi 15236297   87 ARSLPGRTDNEIKNYWRTHFKKKAK 111
Cdd:PLN03091  93 AAQLPGRTDNEIKNLWNSCLKKKLR 117
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 61-106 1.58e-13

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 63.29  E-value: 1.58e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 15236297    61 RGQITPHEESIILELHAKWGNRWSTIARSLPGRTDNEIKNYWRTHF 106
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 8-102 1.15e-12

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 67.12  E-value: 1.15e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236297   8 KGPWTAEEDRLLIEYVRVHGEGRWNSVSKLAGlKRNGKSCRLRWVNYLRPDLKRGQITPHEESIILELHAKWGNRWSTIA 87
Cdd:COG5147  20 GGSWKRTEDEDLKALVKKLGPNNWSKVASLLI-SSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQWSTIA 98

                        90
                ....*....|....*
gi 15236297  88 RSLPGRTDNEIKNYW 102
Cdd:COG5147  99 DYKDRRTAQQCVERY 113
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
8-57 3.43e-12

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 59.54  E-value: 3.43e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 15236297      8 KGPWTAEEDRLLIEYVRVHGEGRWNSVSKLAGlKRNGKSCRLRWVNYLRP 57
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELP-GRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 10-55 1.44e-11

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 57.97  E-value: 1.44e-11
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 15236297  10 PWTAEEDRLLIEYVRVHGEGRWNSVSKLAGlKRNGKSCRLRWVNYL 55
Cdd:cd00167   1 PWTEEEDELLLEAVKKYGKNNWEKIAKELP-GRTPKQCRERWRNLL 45
 
Name Accession Description Interval E-value
PLN03091 PLN03091
hypothetical protein; Provisional
 7-111 2.77e-49

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 168.23  E-value: 2.77e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236297    7 RKGPWTAEEDRLLIEYVRVHGEGRWNSVSKLAGLKRNGKSCRLRWVNYLRPDLKRGQITPHEESIILELHAKWGNRWSTI 86
Cdd:PLN03091  13 RKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGLQRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGNRWSQI 92

                         90       100
                 ....*....|....*....|....*
gi 15236297   87 ARSLPGRTDNEIKNYWRTHFKKKAK 111
Cdd:PLN03091  93 AAQLPGRTDNEIKNLWNSCLKKKLR 117
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
 7-109 1.07e-45

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 153.69  E-value: 1.07e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236297    7 RKGPWTAEEDRLLIEYVRVHGEGRWNSVSKLAGLKRNGKSCRLRWVNYLRPDLKRGQITPHEESIILELHAKWGNRWSTI 86
Cdd:PLN03212  24 KRGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLLRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLGNRWSLI 103

                         90       100
                 ....*....|....*....|...
gi 15236297   87 ARSLPGRTDNEIKNYWRTHFKKK 109
Cdd:PLN03212 104 AGRIPGRTDNEIKNYWNTHLRKK 126
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 61-106 1.58e-13

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 63.29  E-value: 1.58e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 15236297    61 RGQITPHEESIILELHAKWGNRWSTIARSLPGRTDNEIKNYWRTHF 106
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 8-102 1.15e-12

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 67.12  E-value: 1.15e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236297   8 KGPWTAEEDRLLIEYVRVHGEGRWNSVSKLAGlKRNGKSCRLRWVNYLRPDLKRGQITPHEESIILELHAKWGNRWSTIA 87
Cdd:COG5147  20 GGSWKRTEDEDLKALVKKLGPNNWSKVASLLI-SSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQWSTIA 98

                        90
                ....*....|....*
gi 15236297  88 RSLPGRTDNEIKNYW 102
Cdd:COG5147  99 DYKDRRTAQQCVERY 113
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 8-55 1.26e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 60.60  E-value: 1.26e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 15236297     8 KGPWTAEEDRLLIEYVRVHGeGRWNSVSKLAGlKRNGKSCRLRWVNYL 55
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLG-NRWKKIAKLLP-GRTDNQCKNRWQNYL 46
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
8-57 3.43e-12

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 59.54  E-value: 3.43e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 15236297      8 KGPWTAEEDRLLIEYVRVHGEGRWNSVSKLAGlKRNGKSCRLRWVNYLRP 57
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELP-GRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 10-55 1.44e-11

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 57.97  E-value: 1.44e-11
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 15236297  10 PWTAEEDRLLIEYVRVHGEGRWNSVSKLAGlKRNGKSCRLRWVNYL 55
Cdd:cd00167   1 PWTEEEDELLLEAVKKYGKNNWEKIAKELP-GRTPKQCRERWRNLL 45
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 11-70 7.92e-11

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 56.16  E-value: 7.92e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236297    11 WTAEEDRLLIEYVRVHGeGRWNSVSKLAGlKRNGKSCRLRWVNYLRPDLKRGQITPHEES 70
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYG-NDWKQIAKELG-RRTPKQCFDRWRRKLNPKISRGPWSKEEDQ 58
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 65-106 2.85e-10

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 54.50  E-value: 2.85e-10
                        10        20        30        40
                ....*....|....*....|....*....|....*....|...
gi 15236297  65 TPHEESIILELHAKWG-NRWSTIARSLPGRTDNEIKNYWRTHF 106
Cdd:cd00167   3 TEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
61-108 3.71e-10

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 54.15  E-value: 3.71e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 15236297     61 RGQITPHEESIILELHAKWG-NRWSTIARSLPGRTDNEIKNYWRTHFKK 108
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 65-120 4.32e-06

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 43.07  E-value: 4.32e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 15236297    65 TPHEESIILELHAKWGNRWSTIARSLPGRTDNEIKNYWRTHFKKKAKPTTNNAEKI 120
Cdd:pfam13921   2 TEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCFDRWRRKLNPKISRGPWSKEED 57
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 8-94 2.31e-05

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 45.16  E-value: 2.31e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236297   8 KGPWTAEEDRLLIEYVRVHGeGRWNSVSKLAGLKRNgkSCRLRWVNYLRP--DLKRGQITPHEE--------SIILELHA 77
Cdd:COG5147 291 RGKWTKEEEQELAKLVVEHG-GSWTEIGKLLGRMPN--DCRDRWRDYVKCgdTLKRNRWSIEEEelldkvvnEMRLEAQQ 367

                        90
                ....*....|....*..
gi 15236297  78 KWGNRWSTIARSLPGRT 94
Cdd:COG5147 368 SSRILWLLIAQNIRNRL 384
SANT_TRF cd11660
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ...
 10-32 8.85e-04

Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1.


Pssm-ID: 212558 [Multi-domain]  Cd Length: 50  Bit Score: 36.39  E-value: 8.85e-04
                        10        20
                ....*....|....*....|...
gi 15236297  10 PWTAEEDRLLIEYVRVHGEGRWN 32
Cdd:cd11660   2 KWTDEEDEALVEGVEKYGVGNWA 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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