|
Name |
Accession |
Description |
Interval |
E-value |
| pyru_phos_dikin |
TIGR01828 |
pyruvate, phosphate dikinase; This model represents pyruvate,phosphate dikinase, also called ... |
2-864 |
0e+00 |
|
pyruvate, phosphate dikinase; This model represents pyruvate,phosphate dikinase, also called pyruvate,orthophosphate dikinase. It is similar in sequence to other PEP-utilizing enzymes. [Energy metabolism, Other]
Pssm-ID: 273822 [Multi-domain] Cd Length: 856 Bit Score: 1525.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 2 MQRVFTFGkgrsEGNKGMKSLLGGKGANLAEMASIGLSVPPGLTISTEACQQYQIAGKKLPEGLWEEILEGLSFIERDIG 81
Cdd:TIGR01828 1 KKRVYAFG----EGNASMKNLLGGKGANLAEMTKLGLPVPPGFTITTEACNEYYANGKQFPKGLQEEIKEALTLLEEKTG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 82 ASLADPSKPLLLSVRSGAAISMPGMMDTVLNLGLNDQVVVGLAAKSG-ERFAYDSFRRFLDMFGDVVMGIPHAKFEEKLE 160
Cdd:TIGR01828 77 KKFGDTENPLLVSVRSGAAVSMPGMMDTILNLGLNDETVEGLAKLTGnARFAYDSYRRFIQMFGDVVLGIPHELFEQILE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 161 RMKERKGVKNDTDLSAADLKELVEQYKSVYLEAKGQEFPSDPKKQLELAIEAVFDSWDSPRANKYRSINQITGLKGTAVN 240
Cdd:TIGR01828 157 AMKEEKGVKLDTDLTADDLKELIEKYKAIYREATGKPFPQDPKEQLELAIKAVFDSWNNPRAIVYRRLNDIPEDWGTAVN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 241 IQCMVFGNMGDTSGTGVLFTRNPSTGEKKLYGEFLVNAQGEDVVAGIRTPEDLDTMKRFMPEAYAELVENCNILERHYKD 320
Cdd:TIGR01828 237 IQSMVFGNMGETSGTGVAFTRNPSTGEKGLFGEFLINAQGEDVVAGIRTPQPITAMEADMPDVYKELLDIAEKLEGHYRD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 321 MMDIEFTVQEERLWMLQCRAGKRTGKGAVKIAVDMVGEGLVEKSSAIKMVEPQHLDQLLHPQFHDPsgYREKVVAKGLPA 400
Cdd:TIGR01828 317 MQDIEFTIERGKLYMLQTRNGKRTAKAAVRIAVDMVKEGLITEEEAIMRVEPKSLDQLLHPRFDPS--ALKTVLAKGLPA 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 401 SPGAAVGQVVFTAEEAEAWHSQGKTVILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEIRVDE 480
Cdd:TIGR01828 395 SPGAATGKIVFSAEDAVELAEKGKKVILVREETSPEDIEGMHVAEGILTARGGMTSHAAVVARGMGKCCVSGCEELKINE 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 481 NHKVLLIGDLTINEGEWISMNGSTGEVILGKQALAPPALSPDLETFMSWADAIRRLKVMANADTPEDAIAARKNGAQGIG 560
Cdd:TIGR01828 475 EAKTFTIGGRVFHEGDIISIDGSTGEIYLGEIPLIEPSVSGDFETIMDWADKIRKLKVRANADTPEDALTARKFGAEGIG 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 561 LCRTEHMFFGADRIKAVRKMIMAVTTEQRKASLDILLPYQRSDFEGIFRAMDGLPVTIRLLDPPLHEFLPegDLDNIVHE 640
Cdd:TIGR01828 555 LCRTEHMFFGAERIPAVRKMILADSEEERQKALNKLLPFQKEDFKGLFKAMEGLPVTIRLLDPPLHEFLP--HTEELQKE 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 641 LAEETGVKEDEVLSRIEKLSEVNPMLGFRGCRLGISYPELTEMQARAIFEAAASMQDQGVTVIPEIMVPLVGTPQELGHQ 720
Cdd:TIGR01828 633 LAEDMGLTLAEILKRVEELHEVNPMLGHRGCRLGITYPEIYEMQVRAIMEAAVEVKKEGIDVHPEIMIPLVGEKNELKIL 712
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 721 VDVIRKVAKKVFAEKGHTVSYKVGTMIEIPRAALIADEIAKEAEFFSFGTNDLTQMTFGYSRDDVGKFLPIYLAKGILQH 800
Cdd:TIGR01828 713 KDVLEEVAAEVFKEYGVTVPYEIGTMIEIPRAALTADKIAEEADFFSFGTNDLTQMTFGFSRDDAGKFLPKYLEKGILEK 792
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 79475768 801 DPFEVLDQQGVGQLIKMATEKGRAARPSLKVGICGEHGGDPSSVGFFAEAGLDYVSCSPFRVPI 864
Cdd:TIGR01828 793 DPFESLDQTGVGQLMRMAVEKGRQTRPNLKVGICGEHGGDPSSIEFCHKIGLNYVSCSPYRVPI 856
|
|
| PRK05878 |
PRK05878 |
pyruvate phosphate dikinase; Provisional |
20-545 |
9.69e-165 |
|
pyruvate phosphate dikinase; Provisional
Pssm-ID: 235635 [Multi-domain] Cd Length: 530 Bit Score: 490.03 E-value: 9.69e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 20 KSLLGGKGANLAEMASIGLSVPPGLTISTEACQQYQIAGKKLPEGLWEEILEGLSFIERDIGASLADPSKPLLLSVRSGA 99
Cdd:PRK05878 20 RELLGGKGHGIDMMRRLGLPVPPAFCITTEVCVRYLADPGSTIDAIWDDVLDRMRWLEAETGRTFGRGPRPLLVSVRSGA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 100 AISMPGMMDTVLNLGLNDQVVVGLAAKSG-ERFAYDSFRRFLDMFGDVVMgiphakfeeklermkerkgvkndtdlsaad 178
Cdd:PRK05878 100 AQSMPGMMDTILNLGINDAVEQALAAEGGdPDFAADTRRRFTEMYRRIVG------------------------------ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 179 lkelveqyksvyleaKGQEFPSDPKKQLELAIEAVFDSWDSPRANKYRSINQITGLKGTAVNIQCMVFGNMGDTSGTGVL 258
Cdd:PRK05878 150 ---------------SGSPPPDDPYEQLRAAIEAVFASWNSPRAVAYRRHHGLDDDGGTAVVVQAMVFGNLDANSGTGVL 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 259 FTRNPSTGEKKLYGEFLVNAQGEDVVAGIRTPEDLDTMKRFMPEAYAELVENCNILERHYKDMMDIEFTVQEERLWMLQC 338
Cdd:PRK05878 215 FSRNPITGANEPFGEWLPGGQGEDVVSGLVDVAPITALRDEQPAVYDELMAAARTLERLGRDVQDIEFTVESGKLWLLQT 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 339 RAGKRTGKGAVKIAVDMVGEGLVEKSSAIKMVEPQHLDQLLHPQFHDPSGYREKVVAKGLPASPGAAVGQVVFTAEEAEA 418
Cdd:PRK05878 295 RSAKRSAQAAVRLALQLHDEGLIDDAEALRRVTPTHVETLLRPSLQPEARLAAPLLAKGLPACPGVVSGTAYTDVDEALD 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 419 WHSQGKTVILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEirvdenhkvlliGDLTINEGEWI 498
Cdd:PRK05878 375 AADRGEPVILVRDHTRPDDVHGMLAAQGIVTEVGGATSHAAVVSRELGRVAVVGCGA------------GVAAALAGKEI 442
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 79475768 499 SMNGSTGEVILGKQALAPPALS--PDLETFMSWADAIRRLKVMANADTP 545
Cdd:PRK05878 443 TVDGYEGEVRQGVLALSAWSESdtPELRELADIAQRISPLRAHASGDYP 491
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
1-507 |
2.27e-144 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 434.64 E-value: 2.27e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 1 MMQRVFTFgkgrSEGNKGMKSLLGGKGANLAEMASIGLSVPPGLTISTEACQQY-------------------------- 54
Cdd:COG0574 1 MTKYVYWF----AEGGADDVDLVGGKGANLGEMTRLGLPVPPGFTITTEAYRRFleengleeeirelladldvddvdala 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 55 --------QIAGKKLPEGLWEEILEGLSFIERDIGASLadpskplLLSVRSGAA------ISMPGMMDTVLNLglndqvv 120
Cdd:COG0574 77 easaeireLILEAPLPEELEEEILAAYAKLEEKFGEDL-------LVAVRSSATaedlpdASFAGQMDTVLNV------- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 121 vglaakSGErfaydsfrrfldmfgdvvmgiphakfeeklermkerkgvkndtdlsaadlkelveqyksvyleakgqefps 200
Cdd:COG0574 143 ------NGN----------------------------------------------------------------------- 145
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 201 dpkKQLELAIEAVFDSWDSPRANKYRSINQITGLK-GTAVNIQCMVFGNMgdtSGTGVLFTRNPSTGEKK-LYGEFLvNA 278
Cdd:COG0574 146 ---EQLLEAIKAVFASLFTDRAIAYRRHNGIDHDDvGTAVNVQAMVFGNM---SASGVMFTRDPSTGEKDvVYIEAL-NG 218
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 279 QGEDVVAGIRTPEDLDTMKRFM----------------------------------PEAYAELVENCNILERHYKDMMDI 324
Cdd:COG0574 219 LGEDVVAGIVTPDPYYVDKPTIlertlgskaikmvydggtvevpvppeernrpsltDEEYLELARIALRLEKHYGDPQDI 298
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 325 EFTVQEERLWMLQCRAgkrtgkgavkIAVdMvgEGLVEKSsAIKMVEPQHLDQLLHPQFHDPSGYREKVVAKGLPASPGA 404
Cdd:COG0574 299 EWAIDDGKLYILQTRP----------ITV-L--EGLITKE-ALLRVDPAQLDQLLHPRFDPKAKEEGEVLAKGLPASPGA 364
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 405 AVGQVVFTAEEAEaWHSQGKTVILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEIRVdenhkv 484
Cdd:COG0574 365 ASGKVVFIADEAE-LARFQEGVILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATR------ 437
|
570 580
....*....|....*....|...
gi 79475768 485 lligdlTINEGEWISMNGSTGEV 507
Cdd:COG0574 438 ------VLKDGDEITVDGTTGEV 454
|
|
| PEP-utilizers_C |
pfam02896 |
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ... |
517-872 |
5.83e-117 |
|
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.
Pssm-ID: 397163 [Multi-domain] Cd Length: 292 Bit Score: 357.39 E-value: 5.83e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 517 PALSPDLETFMSWADAIRRLKVMANADTPEDAIAARKNGAQGIGLCRTEHMFFGADRIKAVRKmimavtteqrkasldil 596
Cdd:pfam02896 1 KAELGKLKDLPAPTADGTKIKVAANIGTPDDAEAALANGAEGIGLYRTEFLFMDRDELPTEDE----------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 597 lpyQRSDFEGIFRAMDGLPVTIRLLDPPLHEFLPEGDLdnivhelaeetgvkedevlsriekLSEVNPMLGFRGCRLGIS 676
Cdd:pfam02896 64 ---QFEAYKGVLEAMNGRPVTVRTLDIGGDKELPYLEE------------------------PEEMNPFLGWRGIRIGLD 116
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 677 YPELTEMQARAIFEAAASMQdqgvtviPEIMVPLVGTPQELGHQVDVIRKVAKKVFAEKGHTVSYKVGTMIEIPRAALIA 756
Cdd:pfam02896 117 RPELFRTQLRAILRASAFGN-------LRIMFPMVASVEELREAKAIIEEVKEELDAEVGFDKDIKVGIMIEVPSAALLA 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 757 DEIAKEAEFFSFGTNDLTQMTFGYSRDDVGkflPIYLakgilqHDPFEVLDQQGVGQLIKMATEKGraarpsLKVGICGE 836
Cdd:pfam02896 190 DQLAKEVDFFSIGTNDLTQYTLAVDRDNER---VAYL------YDPLHPAVLRLIKEVIRAAHRHG------KWVGICGE 254
|
330 340 350
....*....|....*....|....*....|....*.
gi 79475768 837 HGGDPSSVGFFAEAGLDYVSCSPFRVPIARLAAAQV 872
Cdd:pfam02896 255 MAGDPSAVPLLVGLGLDEFSMSPDSVPRARALLAQI 290
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pyru_phos_dikin |
TIGR01828 |
pyruvate, phosphate dikinase; This model represents pyruvate,phosphate dikinase, also called ... |
2-864 |
0e+00 |
|
pyruvate, phosphate dikinase; This model represents pyruvate,phosphate dikinase, also called pyruvate,orthophosphate dikinase. It is similar in sequence to other PEP-utilizing enzymes. [Energy metabolism, Other]
Pssm-ID: 273822 [Multi-domain] Cd Length: 856 Bit Score: 1525.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 2 MQRVFTFGkgrsEGNKGMKSLLGGKGANLAEMASIGLSVPPGLTISTEACQQYQIAGKKLPEGLWEEILEGLSFIERDIG 81
Cdd:TIGR01828 1 KKRVYAFG----EGNASMKNLLGGKGANLAEMTKLGLPVPPGFTITTEACNEYYANGKQFPKGLQEEIKEALTLLEEKTG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 82 ASLADPSKPLLLSVRSGAAISMPGMMDTVLNLGLNDQVVVGLAAKSG-ERFAYDSFRRFLDMFGDVVMGIPHAKFEEKLE 160
Cdd:TIGR01828 77 KKFGDTENPLLVSVRSGAAVSMPGMMDTILNLGLNDETVEGLAKLTGnARFAYDSYRRFIQMFGDVVLGIPHELFEQILE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 161 RMKERKGVKNDTDLSAADLKELVEQYKSVYLEAKGQEFPSDPKKQLELAIEAVFDSWDSPRANKYRSINQITGLKGTAVN 240
Cdd:TIGR01828 157 AMKEEKGVKLDTDLTADDLKELIEKYKAIYREATGKPFPQDPKEQLELAIKAVFDSWNNPRAIVYRRLNDIPEDWGTAVN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 241 IQCMVFGNMGDTSGTGVLFTRNPSTGEKKLYGEFLVNAQGEDVVAGIRTPEDLDTMKRFMPEAYAELVENCNILERHYKD 320
Cdd:TIGR01828 237 IQSMVFGNMGETSGTGVAFTRNPSTGEKGLFGEFLINAQGEDVVAGIRTPQPITAMEADMPDVYKELLDIAEKLEGHYRD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 321 MMDIEFTVQEERLWMLQCRAGKRTGKGAVKIAVDMVGEGLVEKSSAIKMVEPQHLDQLLHPQFHDPsgYREKVVAKGLPA 400
Cdd:TIGR01828 317 MQDIEFTIERGKLYMLQTRNGKRTAKAAVRIAVDMVKEGLITEEEAIMRVEPKSLDQLLHPRFDPS--ALKTVLAKGLPA 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 401 SPGAAVGQVVFTAEEAEAWHSQGKTVILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEIRVDE 480
Cdd:TIGR01828 395 SPGAATGKIVFSAEDAVELAEKGKKVILVREETSPEDIEGMHVAEGILTARGGMTSHAAVVARGMGKCCVSGCEELKINE 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 481 NHKVLLIGDLTINEGEWISMNGSTGEVILGKQALAPPALSPDLETFMSWADAIRRLKVMANADTPEDAIAARKNGAQGIG 560
Cdd:TIGR01828 475 EAKTFTIGGRVFHEGDIISIDGSTGEIYLGEIPLIEPSVSGDFETIMDWADKIRKLKVRANADTPEDALTARKFGAEGIG 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 561 LCRTEHMFFGADRIKAVRKMIMAVTTEQRKASLDILLPYQRSDFEGIFRAMDGLPVTIRLLDPPLHEFLPegDLDNIVHE 640
Cdd:TIGR01828 555 LCRTEHMFFGAERIPAVRKMILADSEEERQKALNKLLPFQKEDFKGLFKAMEGLPVTIRLLDPPLHEFLP--HTEELQKE 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 641 LAEETGVKEDEVLSRIEKLSEVNPMLGFRGCRLGISYPELTEMQARAIFEAAASMQDQGVTVIPEIMVPLVGTPQELGHQ 720
Cdd:TIGR01828 633 LAEDMGLTLAEILKRVEELHEVNPMLGHRGCRLGITYPEIYEMQVRAIMEAAVEVKKEGIDVHPEIMIPLVGEKNELKIL 712
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 721 VDVIRKVAKKVFAEKGHTVSYKVGTMIEIPRAALIADEIAKEAEFFSFGTNDLTQMTFGYSRDDVGKFLPIYLAKGILQH 800
Cdd:TIGR01828 713 KDVLEEVAAEVFKEYGVTVPYEIGTMIEIPRAALTADKIAEEADFFSFGTNDLTQMTFGFSRDDAGKFLPKYLEKGILEK 792
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 79475768 801 DPFEVLDQQGVGQLIKMATEKGRAARPSLKVGICGEHGGDPSSVGFFAEAGLDYVSCSPFRVPI 864
Cdd:TIGR01828 793 DPFESLDQTGVGQLMRMAVEKGRQTRPNLKVGICGEHGGDPSSIEFCHKIGLNYVSCSPYRVPI 856
|
|
| PRK05878 |
PRK05878 |
pyruvate phosphate dikinase; Provisional |
20-545 |
9.69e-165 |
|
pyruvate phosphate dikinase; Provisional
Pssm-ID: 235635 [Multi-domain] Cd Length: 530 Bit Score: 490.03 E-value: 9.69e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 20 KSLLGGKGANLAEMASIGLSVPPGLTISTEACQQYQIAGKKLPEGLWEEILEGLSFIERDIGASLADPSKPLLLSVRSGA 99
Cdd:PRK05878 20 RELLGGKGHGIDMMRRLGLPVPPAFCITTEVCVRYLADPGSTIDAIWDDVLDRMRWLEAETGRTFGRGPRPLLVSVRSGA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 100 AISMPGMMDTVLNLGLNDQVVVGLAAKSG-ERFAYDSFRRFLDMFGDVVMgiphakfeeklermkerkgvkndtdlsaad 178
Cdd:PRK05878 100 AQSMPGMMDTILNLGINDAVEQALAAEGGdPDFAADTRRRFTEMYRRIVG------------------------------ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 179 lkelveqyksvyleaKGQEFPSDPKKQLELAIEAVFDSWDSPRANKYRSINQITGLKGTAVNIQCMVFGNMGDTSGTGVL 258
Cdd:PRK05878 150 ---------------SGSPPPDDPYEQLRAAIEAVFASWNSPRAVAYRRHHGLDDDGGTAVVVQAMVFGNLDANSGTGVL 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 259 FTRNPSTGEKKLYGEFLVNAQGEDVVAGIRTPEDLDTMKRFMPEAYAELVENCNILERHYKDMMDIEFTVQEERLWMLQC 338
Cdd:PRK05878 215 FSRNPITGANEPFGEWLPGGQGEDVVSGLVDVAPITALRDEQPAVYDELMAAARTLERLGRDVQDIEFTVESGKLWLLQT 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 339 RAGKRTGKGAVKIAVDMVGEGLVEKSSAIKMVEPQHLDQLLHPQFHDPSGYREKVVAKGLPASPGAAVGQVVFTAEEAEA 418
Cdd:PRK05878 295 RSAKRSAQAAVRLALQLHDEGLIDDAEALRRVTPTHVETLLRPSLQPEARLAAPLLAKGLPACPGVVSGTAYTDVDEALD 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 419 WHSQGKTVILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEirvdenhkvlliGDLTINEGEWI 498
Cdd:PRK05878 375 AADRGEPVILVRDHTRPDDVHGMLAAQGIVTEVGGATSHAAVVSRELGRVAVVGCGA------------GVAAALAGKEI 442
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 79475768 499 SMNGSTGEVILGKQALAPPALS--PDLETFMSWADAIRRLKVMANADTP 545
Cdd:PRK05878 443 TVDGYEGEVRQGVLALSAWSESdtPELRELADIAQRISPLRAHASGDYP 491
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
1-507 |
2.27e-144 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 434.64 E-value: 2.27e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 1 MMQRVFTFgkgrSEGNKGMKSLLGGKGANLAEMASIGLSVPPGLTISTEACQQY-------------------------- 54
Cdd:COG0574 1 MTKYVYWF----AEGGADDVDLVGGKGANLGEMTRLGLPVPPGFTITTEAYRRFleengleeeirelladldvddvdala 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 55 --------QIAGKKLPEGLWEEILEGLSFIERDIGASLadpskplLLSVRSGAA------ISMPGMMDTVLNLglndqvv 120
Cdd:COG0574 77 easaeireLILEAPLPEELEEEILAAYAKLEEKFGEDL-------LVAVRSSATaedlpdASFAGQMDTVLNV------- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 121 vglaakSGErfaydsfrrfldmfgdvvmgiphakfeeklermkerkgvkndtdlsaadlkelveqyksvyleakgqefps 200
Cdd:COG0574 143 ------NGN----------------------------------------------------------------------- 145
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 201 dpkKQLELAIEAVFDSWDSPRANKYRSINQITGLK-GTAVNIQCMVFGNMgdtSGTGVLFTRNPSTGEKK-LYGEFLvNA 278
Cdd:COG0574 146 ---EQLLEAIKAVFASLFTDRAIAYRRHNGIDHDDvGTAVNVQAMVFGNM---SASGVMFTRDPSTGEKDvVYIEAL-NG 218
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 279 QGEDVVAGIRTPEDLDTMKRFM----------------------------------PEAYAELVENCNILERHYKDMMDI 324
Cdd:COG0574 219 LGEDVVAGIVTPDPYYVDKPTIlertlgskaikmvydggtvevpvppeernrpsltDEEYLELARIALRLEKHYGDPQDI 298
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 325 EFTVQEERLWMLQCRAgkrtgkgavkIAVdMvgEGLVEKSsAIKMVEPQHLDQLLHPQFHDPSGYREKVVAKGLPASPGA 404
Cdd:COG0574 299 EWAIDDGKLYILQTRP----------ITV-L--EGLITKE-ALLRVDPAQLDQLLHPRFDPKAKEEGEVLAKGLPASPGA 364
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 405 AVGQVVFTAEEAEaWHSQGKTVILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEIRVdenhkv 484
Cdd:COG0574 365 ASGKVVFIADEAE-LARFQEGVILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATR------ 437
|
570 580
....*....|....*....|...
gi 79475768 485 lligdlTINEGEWISMNGSTGEV 507
Cdd:COG0574 438 ------VLKDGDEITVDGTTGEV 454
|
|
| PEP-utilizers_C |
pfam02896 |
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ... |
517-872 |
5.83e-117 |
|
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.
Pssm-ID: 397163 [Multi-domain] Cd Length: 292 Bit Score: 357.39 E-value: 5.83e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 517 PALSPDLETFMSWADAIRRLKVMANADTPEDAIAARKNGAQGIGLCRTEHMFFGADRIKAVRKmimavtteqrkasldil 596
Cdd:pfam02896 1 KAELGKLKDLPAPTADGTKIKVAANIGTPDDAEAALANGAEGIGLYRTEFLFMDRDELPTEDE----------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 597 lpyQRSDFEGIFRAMDGLPVTIRLLDPPLHEFLPEGDLdnivhelaeetgvkedevlsriekLSEVNPMLGFRGCRLGIS 676
Cdd:pfam02896 64 ---QFEAYKGVLEAMNGRPVTVRTLDIGGDKELPYLEE------------------------PEEMNPFLGWRGIRIGLD 116
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 677 YPELTEMQARAIFEAAASMQdqgvtviPEIMVPLVGTPQELGHQVDVIRKVAKKVFAEKGHTVSYKVGTMIEIPRAALIA 756
Cdd:pfam02896 117 RPELFRTQLRAILRASAFGN-------LRIMFPMVASVEELREAKAIIEEVKEELDAEVGFDKDIKVGIMIEVPSAALLA 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 757 DEIAKEAEFFSFGTNDLTQMTFGYSRDDVGkflPIYLakgilqHDPFEVLDQQGVGQLIKMATEKGraarpsLKVGICGE 836
Cdd:pfam02896 190 DQLAKEVDFFSIGTNDLTQYTLAVDRDNER---VAYL------YDPLHPAVLRLIKEVIRAAHRHG------KWVGICGE 254
|
330 340 350
....*....|....*....|....*....|....*.
gi 79475768 837 HGGDPSSVGFFAEAGLDYVSCSPFRVPIARLAAAQV 872
Cdd:pfam02896 255 MAGDPSAVPLLVGLGLDEFSMSPDSVPRARALLAQI 290
|
|
| PEP_synth |
TIGR01418 |
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member ... |
13-872 |
3.15e-66 |
|
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273612 [Multi-domain] Cd Length: 786 Bit Score: 236.56 E-value: 3.15e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 13 SEGNKGMKSLLGGKGANLAEM----ASIGLSVPPGLTISTEACQQYqiagkkLPE-GLWEEILEGLSFIERDIGASLADP 87
Cdd:TIGR01418 6 EEVRKDDVPLVGGKNASLGEMiqnlSPAGVPVPPGFVVTAEAYRYF------LEEnGIAQKIRDLLEELDVEDVDALAAA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 88 SKplllSVRSGaaismpgMMDTVLNLGLNDQVvvglaaksgeRFAYDsfrrfldmfgdvvmgiphaKFEEKLERMKERKG 167
Cdd:TIGR01418 80 SA----EIREL-------ILNTPFPPDLEEAI----------REAYD-------------------KLSEDYGKEEADVA 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 168 VKNDTdlSAADLKE--LVEQyKSVYLEAKGQEfpsdpkkQLELAIEAVFDSWDSPRANKYRSINQITGLK-GTAVNIQCM 244
Cdd:TIGR01418 120 VRSSA--TAEDLPDasFAGQ-QETYLNVTGEE-------EVLEHVKKCWASLFTDRAISYRVSQGFDHEKvAIAVGVQKM 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 245 VFGNMGDTsgtGVLFTRNPSTGEKKlygEFLVNAQ---GEDVVAGIRTPE-------DLDTMKRFMPEA----------Y 304
Cdd:TIGR01418 190 VRSDLGSS---GVMFTIDTETGFKD---AVFIESAwglGEAVVGGAVTPDeyvvfkpTLEQGKKAILERtlgskkikmvY 263
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 305 A-----------------------------ELVENCNILERHYKDMMDIEFTV--QEERLWMLQCRAGKRTGKGavkiav 353
Cdd:TIGR01418 264 DpdgggvetkivevpeeerdafslsdeeilELAKLAVLIEKHYGRPMDIEWAKdgFDGEIFIVQARPETVQSRK------ 337
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 354 dmvGEGLVEKSSAIKMvepqhldqllhpqfhdpsgyREKVVAKGLPASPGAAVG--QVVFTAEEAeawHSQGKTVILVRT 431
Cdd:TIGR01418 338 ---KKENVEERYELKG--------------------KGKVLVTGRAAGPGIASGkvKVIFDLKEM---DKFEEGDILVTD 391
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 432 ETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCseirvdenhkvlliGDLT--INEGEWISMNGS---TGE 506
Cdd:TIGR01418 392 MTDPDWEPAMKRASAIVTNEGGMTCHAAIVARELGIPAVVGT--------------GDATktLKDGMEVTVDCAegdTGY 457
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 507 VILGKqaLAPPALSPDLETFmswadAIRRLKVMANADTPEDAIAARKNGAQGIGLCRTEHMFFGADRIKAVRKMIMAVTT 586
Cdd:TIGR01418 458 VYAGK--LEHEVKEVELSNM-----PVTATKIYMNVGNPEVAFRFAALPNDGVGLARIEFIILNWIGKHPLALIDDDDLE 530
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 587 EQRKASLDILLPYQRSDF------EGIFR---AMDGLPVTIRLLDPPLHEFlpegdldnivhelAEETGVKEDEvlsrie 657
Cdd:TIGR01418 531 SVEKNEIEELMAGNPRDFfvdklaEGIAKvaaAFYPKPVIVRTSDFKSNEY-------------RNLIGGEEYE------ 591
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 658 kLSEVNPMLGFRGCRLGIS--YPELTEMQARAIFEAAASMqdqGVTVIpEIMVPLVGTPQELghqvdvirKVAKKVFAEK 735
Cdd:TIGR01418 592 -PDEENPMLGWRGASRYYSesYEEAFRLECRAIKRVREEM---GLTNV-EVMIPFVRTPEEG--------KRALEIMAEE 658
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 736 GHTV---SYKVGTMIEIPRAALIADEIAKEAEFFSFGTNDLTQMTFGYSRDDvgkflpiylakGILQHdpfeVLDQQ--G 810
Cdd:TIGR01418 659 GLRRgknGLEVYVMCEVPSNALLADEFAKEFDGFSIGSNDLTQLTLGVDRDS-----------GLVAH----LFDERnpA 723
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 79475768 811 VGQLIKMATEKgrAARPSLKVGICGEHGGD-PSSVGFFAEAGLDYVSCSPFRVPIARLAAAQV 872
Cdd:TIGR01418 724 VLRLIEMAIKA--AKEHGKKVGICGQAPSDyPEVVEFLVEEGIDSISLNPDAVLRTRLQVAEV 784
|
|
| PtsA |
COG1080 |
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ... |
426-866 |
4.44e-58 |
|
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];
Pssm-ID: 440698 [Multi-domain] Cd Length: 571 Bit Score: 208.78 E-value: 4.44e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 426 VILVRTETSPDDVGGMHAAE--GILTARGGMTSHAAVVARGWGKCCIAGCSEIRvdenhkvlligdLTINEGEWISMNGS 503
Cdd:COG1080 155 VILVAHDLTPSDTAQLDPSRvaGFVTDLGGRTSHTAILARSLGIPAVVGLGDAL------------LLVKDGDLVIVDGD 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 504 TGEVILgkqalAPPAlsPDLETFMSWADAIRRLK--------------------VMANADTPEDAIAARKNGAQGIGLCR 563
Cdd:COG1080 223 AGVVIV-----NPDE--ETLAEYRERQAEYAAERaelarlrdlpavtldgvrveLAANIGLPEDAAAALENGAEGVGLFR 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 564 TEHMFFGADRikavrkmimAVT-TEQRKAsldillpYQRsdfegIFRAMDGLPVTIRLLD-------PPLHefLPEgdld 635
Cdd:COG1080 296 TEFLFMDRDD---------LPTeEEQFEA-------YRA-----VAEAMGGRPVTIRTLDiggdkplPYLP--LPK---- 348
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 636 nivhelaeetgvkedevlsrieklsEVNPMLGFRGCRLGISYPELTEMQARAIFEAAA--SMQdqgvtvipeIMVPLVGT 713
Cdd:COG1080 349 -------------------------EENPFLGLRAIRLCLDRPELFRTQLRAILRASAhgNLR---------IMFPMISS 394
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 714 PQELgHQV-DVIRKVAKKVfAEKGHTVS--YKVGTMIEIPRAALIADEIAKEAEFFSFGTNDLTQMTFGYSRDD--VGkf 788
Cdd:COG1080 395 VEEL-RQAkALLEEAKAEL-RAEGIPFDedIPVGIMIEVPAAALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNekVA-- 470
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 789 lpiYLakgilqHDPFE--VLdqqgvgQLIKMATEKGRAA-RPslkVGICGEHGGDPSSVGFFAEAGLDYVSCSPFRVPIA 865
Cdd:COG1080 471 ---YL------YDPLHpaVL------RLIKMVIDAAHKAgKP---VGVCGEMAGDPLATPLLLGLGLDELSMSPSSIPAV 532
|
.
gi 79475768 866 R 866
Cdd:COG1080 533 K 533
|
|
| PRK06464 |
PRK06464 |
phosphoenolpyruvate synthase; Validated |
22-872 |
5.37e-58 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235809 [Multi-domain] Cd Length: 795 Bit Score: 213.07 E-value: 5.37e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 22 LLGGKGANLAEM----ASIGLSVPPGLTISTEA-------------------------CQQYQIAGKK---------LPE 63
Cdd:PRK06464 20 LVGGKNASLGEMisnlSGAGVPVPPGFATTAEAyryfleqtglnekiyelldgldvddVDALAKAGAQirqliidtpFPP 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 64 GLWEEILEGLsfieRDIGASLADPSkpllLSVRSGA-AISMP-----GMMDTVLNlglndqvVVGLaaksgerfaydsfr 137
Cdd:PRK06464 100 DLEQEIREAY----AKLSAGYGEAS----VAVRSSAtAEDLPdasfaGQQETFLN-------VRGI-------------- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 138 rfldmfgdvvmgiphakfEEKLERMKErkgvkndtdlsaadlkelveqyksvyleakgqefpsdpkkqlelaieaVFDSW 217
Cdd:PRK06464 151 ------------------DDVLEAVKE------------------------------------------------CFASL 164
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 218 DSPRANKYRSINQITGLK-GTAVNIQCMVFGnmgDTSGTGVLFTRNPSTGEKKL------YGefLvnaqGEDVVAGIRTP 290
Cdd:PRK06464 165 FTDRAISYRVHQGFDHFKvALSAGVQKMVRS---DLAASGVMFTLDTESGFRDVvfitasWG--L----GEMVVQGAVNP 235
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 291 E----DLDTM--------------KRFM----------------PEAYA-----------ELVENCNILERHYKDMMDIE 325
Cdd:PRK06464 236 DefyvHKPTLkagkpaivrrtlgsKKIKmvyddggehgvktvdvPEEERnrfsltdeevlELAKQAVIIEKHYGRPMDIE 315
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 326 FTV--QEERLWMLQCRAgkRTgkgavkiavdmvgeglVEKSSAIKMVEPQHLDQllhpqfhdpsgyREKVVAKGLPASPG 403
Cdd:PRK06464 316 WAKdgDDGKLYIVQARP--ET----------------VKSRKEANVLERYKLKG------------QGKVLVEGRAIGPG 365
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 404 AAVG--QVVFTAEEAEAWhSQGKtvILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEIRvden 481
Cdd:PRK06464 366 IGSGkvRVILDISEMDKV-QPGD--VLVTDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGTGNAT---- 438
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 482 hKVLLIGDL-TINEGEwismnGSTGEVILGKqaLAPPALSPDLETFmswadAIRRLKVMANADTPEDAIAARKNGAQGIG 560
Cdd:PRK06464 439 -EVLKDGQEvTVSCAE-----GDTGYVYEGL--LEFEVEEVSLEEM-----PETPTKIMMNVGNPERAFDFAALPNDGVG 505
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 561 LCRTEHMFfgADRIKAVRKMIM---AVTTEQRKASLDILLPYQ-RSDF------EGI---FRAMDGLPVTIRLLDPPLHE 627
Cdd:PRK06464 506 LARLEFII--NNMIGVHPLALLefdQQDADLKAEIEELTAGYAsPEEFyvdklaEGIatvAAAFYPKPVIVRLSDFKSNE 583
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 628 F--LPEGDLdnivHELAEEtgvkedevlsrieklsevNPMLGFRGCRLGIS--YPELTEMQARAIFEAAASMqdqGVTVI 703
Cdd:PRK06464 584 YanLIGGER----YEPEEE------------------NPMLGFRGASRYLSesFREAFALECEAIKRVREEM---GLTNV 638
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 704 pEIMVPLVGTPQElghqvdvIRKVaKKVFAEKG---HTVSYKVGTMIEIPRAALIADEIAKEAEFFSFGTNDLTQMTFGY 780
Cdd:PRK06464 639 -EVMIPFVRTVEE-------AEKV-IELLAENGlkrGENGLKVIMMCEIPSNALLAEEFLEYFDGFSIGSNDLTQLTLGL 709
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 781 SRDDvgkflpiylakGILQHDpFEVLDqQGVGQLIKMATEKGRAARpsLKVGICGEHGGD-PSSVGFFAEAGLDYVSCSP 859
Cdd:PRK06464 710 DRDS-----------GLVAHL-FDERN-PAVKKLISMAIKAAKKAG--KYVGICGQAPSDhPDFAEWLVEEGIDSISLNP 774
|
970
....*....|...
gi 79475768 860 FRVPIARLAAAQV 872
Cdd:PRK06464 775 DAVVDTWLAVAEV 787
|
|
| PPDK_N |
pfam01326 |
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible ... |
21-360 |
1.93e-46 |
|
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP). The N-terminal domain has been shown to be the AMP/ATP-binding domain.
Pssm-ID: 426201 [Multi-domain] Cd Length: 326 Bit Score: 169.31 E-value: 1.93e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 21 SLLGGKGANLAEM-ASIGLSVPPGLTISTEACQQY-------------------------QIAGKK---------LPEGL 65
Cdd:pfam01326 2 NLVGGKGANLGEMlNDAGIPVPPGFAITADAYREFleenglrekidellkdldvddvdelREASKEirqlilsapLPEEL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 66 WEEILEglsfIERDIGASLADPskPLLLSVRSGAAI------SMPGMMDTVLNLGLNDQVVVglaaksgerfaydsfrrf 139
Cdd:pfam01326 82 EEAIRE----AYEELGKKFGDE--PLPVAVRSSATAedlpdaSFAGQQDTYLNVGGNDEVLE------------------ 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 140 ldmfgdvvmgiphakfeeklermkerkgvkndtdlsaadlkelveqyksvyleakgqefpsdpkkqlelAIEAVFDSWDS 219
Cdd:pfam01326 138 ---------------------------------------------------------------------AIKAVFASLFN 148
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 220 PRANKYRSINQITGLK-GTAVNIQCMVFGNmgdtsGTGVLFTRNPSTGEKklyGEFLVNA---QGEDVVAGIRTP----- 290
Cdd:pfam01326 149 DRAIAYRREKGIDHEDvALAVGVQRMVRSD-----ASGVMFSRDPETGFR---DEVLINAswgLGEAVVQGRVTPdefyv 220
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 291 -----------------------EDLDTMKRFMPEAYA-----------ELVENCNILERHYKDMMDIEFTVQ--EERLW 334
Cdd:pfam01326 221 fkptleilrrtigekeikmvydeGGEGTKEVEVPEEKRerfslsdeevlELARIAKKIEKHYGTPMDIEWAIDgrDGKLY 300
|
410 420
....*....|....*....|....*.
gi 79475768 335 MLQCRAGKRTGKGAVKIAVDMVGEGL 360
Cdd:pfam01326 301 ILQARPETVWSEAMEKIAAEILEEGL 326
|
|
| PTS_I_fam |
TIGR01417 |
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ... |
424-866 |
8.19e-39 |
|
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.
Pssm-ID: 273611 [Multi-domain] Cd Length: 565 Bit Score: 152.64 E-value: 8.19e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 424 KTVILVRTETSPDDVGGMHA--AEGILTARGGMTSHAAVVARGWGKCCIAGCSEIrvdenhkvlligDLTINEGEWISMN 501
Cdd:TIGR01417 153 DEVILVAEDLTPSETAQLNLkyVKGFLTDAGGKTSHTAIMARSLEIPAIVGTKSV------------TSQVKNGDTVIID 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 502 GSTGEVILgkqalappalSPDLETFMSWADAIRR-----------------------LKVMANADTPEDAIAARKNGAQG 558
Cdd:TIGR01417 221 GVKGIVIF----------NPSSETIDKYEAKQEAvssekaelaklkdkpaitldghqVELAANIGTVDDVEGAERNGGEG 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 559 IGLCRTEHMFFGADRikavrkmimavtteqrkasldilLPYQRSDFEG---IFRAMDGLPVTIRLLDpplheflpegdld 635
Cdd:TIGR01417 291 IGLFRTEFLYMSRDQ-----------------------LPTEEEQFAAyktVLEAMESDAVIVRTLD------------- 334
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 636 nivhelaeetgVKEDEVLSRIEKLSEVNPMLGFRGCRLGISYPELTEMQARAIFEAAasmqDQGVTvipEIMVPLVGTPQ 715
Cdd:TIGR01417 335 -----------IGGDKELPYLNFPKEENPFLGYRAIRLALEREEILRTQLRAILRAS----AYGKL---RIMFPMVATVE 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 716 ELgHQVDVIRKVAKKVFAEKGHTVS--YKVGTMIEIPRAALIADEIAKEAEFFSFGTNDLTQMTFGYSRddvGKFLPIYL 793
Cdd:TIGR01417 397 EI-RAVKQELEEEKQELNDEGKAFDenIEVGVMIEIPSAALIADHLAKEVDFFSIGTNDLTQYTLAVDR---GNDLISNL 472
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 79475768 794 akgilqHDPFevldQQGVGQLIKMATEKGRAArpSLKVGICGEHGGDPSSVGFFAEAGLDYVSCSPFRVPIAR 866
Cdd:TIGR01417 473 ------YQPY----NPAVLRLIKLVIDAAKAE--GIWVGMCGEMAGDERAIPLLLGLGLRELSMSASSILRIK 533
|
|
| PRK11177 |
PRK11177 |
phosphoenolpyruvate-protein phosphotransferase PtsI; |
426-863 |
4.84e-26 |
|
phosphoenolpyruvate-protein phosphotransferase PtsI;
Pssm-ID: 183017 [Multi-domain] Cd Length: 575 Bit Score: 113.95 E-value: 4.84e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 426 VILVRTETSPDDVGGMHAAE--GILTARGGMTSHAAVVARGWGKCCIAGCSEIRVDENHKVLLIGDLTINEgewISMNGS 503
Cdd:PRK11177 156 VILVAADLTPSETAQLNLKKvlGFITDIGGRTSHTSIMARSLELPAIVGTGNITKQVKNGDYLILDAVNNQ---IYVNPT 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 504 TGEV----------ILGKQALAP----PALSPDLetfmswadaiRRLKVMANADTPEDAIAARKNGAQGIGLCRTEHMFF 569
Cdd:PRK11177 233 NEVIeelkavqeqyASEKAELAKlkdlPAITLDG----------HQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFM 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 570 GADrikavrkmimAVTTEQRkasldillpyQRSDFEGIFRAMDGLPVTIRLLDpplheflpegdldnivhelaeetgVKE 649
Cdd:PRK11177 303 DRD----------ALPTEEE----------QFQAYKAVAEAMGSQAVIVRTMD------------------------IGG 338
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 650 DEVLSRIEKLSEVNPMLGFRGCRLGISYPELTEMQARAIFEAAASMQDQgvtvipeIMVPLVGTPQELGHQVDVIRKVAK 729
Cdd:PRK11177 339 DKELPYMNLPKEENPFLGWRAIRIAMDRKEILHDQLRAILRASAFGKLR-------IMFPMIISVEEVRELKAEIEILKQ 411
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 730 KVFAE-KGHTVSYKVGTMIEIPRAALIADEIAKEAEFFSFGTNDLTQMTFGYSRddvGKFLPIYLakgilqHDPFE--VL 806
Cdd:PRK11177 412 ELRDEgKAFDESIEIGVMVETPAAAVIARHLAKEVDFFSIGTNDLTQYTLAVDR---GNELISHL------YNPMSpsVL 482
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 79475768 807 dqqgvgQLIKMATEKGRAARpslK-VGICGEHGGDPSSVGFFAEAGLDYVSCSPFRVP 863
Cdd:PRK11177 483 ------NLIKQVIDASHAEG---KwTGMCGELAGDERATLLLLGMGLDEFSMSAISIP 531
|
|
| PEP-utilizers |
pfam00391 |
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain ... |
426-505 |
3.97e-24 |
|
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain which is thought to be mobile in all proteins known to contain it.
Pssm-ID: 459796 [Multi-domain] Cd Length: 73 Bit Score: 96.33 E-value: 3.97e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 426 VILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEIRVdenhkvlligdlTINEGEWISMNGSTG 505
Cdd:pfam00391 6 VILVAPDTTPSDTAGLDKAAGIVTERGGMTSHAAIVARELGIPAVVGVGDATI------------LLKEGDLVTVDGSTG 73
|
|
| PRK11061 |
PRK11061 |
phosphoenolpyruvate--protein phosphotransferase; |
446-858 |
7.77e-17 |
|
phosphoenolpyruvate--protein phosphotransferase;
Pssm-ID: 182937 [Multi-domain] Cd Length: 748 Bit Score: 85.43 E-value: 7.77e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 446 GILTARGGMTSHAAVVARGWGKCCIAGcSEIRVDENHKVLLI-----GDLTINEG-----EWISMNGSTGEVI-LGKQAL 514
Cdd:PRK11061 345 GVVVRDGAANSHAAILVRALGIPTVMG-ADIQPSLLHQRLLIvdgyrGELLVDPEpvllqEYQRLISEEIELSrLAEDDV 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 515 APPALSPDLEtfmswadairRLKVMANADTPEDAIAARKNGAQGIGLCRTEHMFfgadrikavrkMImavttEQRKASLD 594
Cdd:PRK11061 424 NLPAQLKSGE----------RIKVMLNAGLSAEHEEKLGSRVDGVGLYRTEIPF-----------ML-----QSGFPSEE 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 595 illpYQRSDFEGIFRAMDGLPVTIRLLD----PPLhEFLPegdldnivhelaeetgvkedevlsriekLSEVNPMLGFRG 670
Cdd:PRK11061 478 ----EQVAQYQGMLQMFPDKPVTLRTLDigadKQL-PYMP----------------------------ISEENPCLGWRG 524
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 671 CRLGISYPELTEMQARAIFEAAASMQDQGvtvipeIMVPLVGTPQELGHQVDVIRKVAKKVFAEKGHTVSY-KVGTMIEI 749
Cdd:PRK11061 525 IRITLDQPEIFLIQVRAMLRANAATGNLS------ILLPMVTSIDEVDEARRLIDRAGREVEEMLGYEIPKpRIGIMIEV 598
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 750 PRAALIADEIAKEAEFFSFGTNDLTQMTFGYSRDD--VGkflpiylakgilqhDPFEVLdQQGVGQLIKMATEKgrAARP 827
Cdd:PRK11061 599 PSMVFMLPHLASRVDFISVGTNDLTQYLLAVDRNNtrVA--------------SLYDSL-HPAMLRALKMIADE--AEQH 661
|
410 420 430
....*....|....*....|....*....|.
gi 79475768 828 SLKVGICGEHGGDPssVGFFAEAGLDYVSCS 858
Cdd:PRK11061 662 GLPVSLCGEMAGDP--MGALLLIGLGYRHLS 690
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
1-340 |
2.61e-11 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 67.61 E-value: 2.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 1 MMQRVFTFGkgrsEGNKGMKSLLGGKGANLAEMASIGLSVPPGLTISTEACQQYQIAGKKLpeglwEEILEGLSFIERDI 80
Cdd:PRK06241 1 MSSYVLDFQ----EIDKTQLPLVGGKGANLGELSRAGIPVPEGFCVTTEAYKKFLEQNEEF-----DALLDQLSALKLED 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 81 GASLADPSKPLLLSVRSgaaISMPgmmdtvlnlglnDQVVVGLA---AKSGERFAY---------DSfrrfldmfgdvvm 148
Cdd:PRK06241 72 REQIGEISAKIREVIEA---IEIP------------EDIVEAIAaalSKFGEDHAYavrssataeDL------------- 123
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 149 giPHAKFeeklermkerkgvkndtdlsAAdlkelveQYKSvYLEAKGqefpsdpKKQLELAIEAVFDSWDSPRANKYRSI 228
Cdd:PRK06241 124 --PTASF--------------------AG-------QQDT-YLNVIG-------KDAILQHIRKCWASLFTERAVIYRIQ 166
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 229 NQItGLKGT--AVNIQCMVFgnmGDTSgtGVLFTRNPSTGEKKLYgefLVNAQ---GEDVVAGI--------RTPEDLD- 294
Cdd:PRK06241 167 NGF-DHRKVymSVVVQKMVF---PEAS--GIMFTADPVTGNRKVL---SIDASfglGEALVSGLvsadtykvREGKIIDk 237
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 79475768 295 ----------------TMKRFMPEAYA-----------ELVENCNILERHYKDMMDIEFTVQEERLWMLQCRA 340
Cdd:PRK06241 238 tiatkklaiyalkeggTETKEIEPEQQksqtltdeqilELARLGRKIEAHFGCPQDIEWCLADGTFYILQSRP 310
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
392-510 |
1.04e-09 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 60.68 E-value: 1.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 392 KVVAKGLPASPGAAVGQVVF--TAEEAEAWHSQGKtvILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCC 469
Cdd:COG3848 210 DVLAKGQGIGRGSVTGKAVVarSAEEALEKFEEGD--ILVVPSTDAEFVPAIEKAAGIITEEGGLTSHAAIVGLELGIPV 287
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 79475768 470 IAGCSeirvdenhkvlliGDLT-INEGEWISMNGSTGEVILG 510
Cdd:COG3848 288 IVGAE-------------GATEiLKDGQVVTVDAERGVVYRG 316
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
397-509 |
5.01e-08 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 56.82 E-value: 5.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 397 GLPASPGAAVGQ--VVFTAEEAEAwhSQGKtvILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGcs 474
Cdd:PRK06241 770 GLPVSSGVVEGRarVILNPEDADL--EKGD--ILVTAFTDPGWTPLFVSIKGLVTEVGGLMTHGAVIAREYGIPAVVG-- 843
|
90 100 110
....*....|....*....|....*....|....*..
gi 79475768 475 eirvdenhkvllIGDLT--INEGEWISMNGSTGEVIL 509
Cdd:PRK06241 844 ------------VENATklIKDGQRIRVDGTEGYVEI 868
|
|
| PRK08296 |
PRK08296 |
hypothetical protein; Provisional |
396-507 |
9.29e-06 |
|
hypothetical protein; Provisional
Pssm-ID: 181362 Cd Length: 603 Bit Score: 49.27 E-value: 9.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 396 KGLPASPGAAVG--QVVFTAEEAEAWHsQGKtvILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGC 473
Cdd:PRK08296 501 KGFAASPGVVEGpaRVIRSADELSEVQ-EGE--ILVCPVTSPSWAPIFAKIKATVTDIGGVMSHAAIVCREYGLPAVVGT 577
|
90 100 110
....*....|....*....|....*....|....
gi 79475768 474 SeirvdenhkvllIGDLTINEGEWISMNGSTGEV 507
Cdd:PRK08296 578 G------------NATKRIKTGQRLRVDGTKGVV 599
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
392-510 |
1.61e-05 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 48.38 E-value: 1.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79475768 392 KVVAKGLPASPGAAVGQVVF--TAEEAEAWHSQGktvILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCC 469
Cdd:PRK06354 480 AVVAKGQGIGRKSVSGKARVakTAAEVAKVNEGD---ILVTPSTDADMIPAIEKAAAIITEEGGLTSHAAVVGLRLGIPV 556
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 79475768 470 IAGCSEIrvdenhkvlligDLTINEGEWISMNGSTGEVILG 510
Cdd:PRK06354 557 IVGVKNA------------TSLIKDGQIITVDAARGVVYSG 585
|
|
| |
