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Conserved domains on  [gi|240256075|ref|NP_194376|]
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S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Methyltransf_7 super family cl04109
SAM dependent carboxyl methyltransferase; This family of plant methyltransferases contains ...
 46-110 1.41e-12

SAM dependent carboxyl methyltransferase; This family of plant methyltransferases contains enzymes that act on a variety of substrates including salicylic acid, jasmonic acid and 7-Methylxanthine. Caffeine is synthesized through sequential three-step methylation of xanthine derivatives at positions 7-N, 3-N, and 1-N. The protein 7-methylxanthine methyltransferase (designated as CaMXMT) catalyzes the second step to produce theobromine.


The actual alignment was detected with superfamily member pfam03492:

Pssm-ID: 470949  Cd Length: 326  Bit Score: 62.19  E-value: 1.41e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240256075   46 FPMSYLHVAVSSRVLHILSKVPEKVV-ENG--WNKRKAWIEG-SDRQVLMGYAEQADKDLVDFLAepCR 110
Cdd:pfam03492 103 FPSNSLHFVHSSYSLHWLSQVPEGLEdKNSpaLNKGNIYISGtSPPEVVKAYLRQFQKDFSLFLK--AR 169
 
Name Accession Description Interval E-value
Methyltransf_7 pfam03492
SAM dependent carboxyl methyltransferase; This family of plant methyltransferases contains ...
 46-110 1.41e-12

SAM dependent carboxyl methyltransferase; This family of plant methyltransferases contains enzymes that act on a variety of substrates including salicylic acid, jasmonic acid and 7-Methylxanthine. Caffeine is synthesized through sequential three-step methylation of xanthine derivatives at positions 7-N, 3-N, and 1-N. The protein 7-methylxanthine methyltransferase (designated as CaMXMT) catalyzes the second step to produce theobromine.


Pssm-ID: 460946  Cd Length: 326  Bit Score: 62.19  E-value: 1.41e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240256075   46 FPMSYLHVAVSSRVLHILSKVPEKVV-ENG--WNKRKAWIEG-SDRQVLMGYAEQADKDLVDFLAepCR 110
Cdd:pfam03492 103 FPSNSLHFVHSSYSLHWLSQVPEGLEdKNSpaLNKGNIYISGtSPPEVVKAYLRQFQKDFSLFLK--AR 169
PLN02668 PLN02668
indole-3-acetate carboxyl methyltransferase
 32-105 3.27e-06

indole-3-acetate carboxyl methyltransferase


Pssm-ID: 178273  Cd Length: 386  Bit Score: 44.09  E-value: 3.27e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 240256075  32 YRHAPLPRNIFGPMFPMSYLHVAVSSRVLHILSKVPEKVVEN---GWNKRKAWIEGSDRQVLMGYAEQADKDLVDFL 105
Cdd:PLN02668 144 YFAAGVPGSFYRRLFPARSIDVFHSAFSLHWLSQVPESVTDKrsaAYNKGRVFIHGASESTANAYKRQFQADLAGFL 220
 
Name Accession Description Interval E-value
Methyltransf_7 pfam03492
SAM dependent carboxyl methyltransferase; This family of plant methyltransferases contains ...
 46-110 1.41e-12

SAM dependent carboxyl methyltransferase; This family of plant methyltransferases contains enzymes that act on a variety of substrates including salicylic acid, jasmonic acid and 7-Methylxanthine. Caffeine is synthesized through sequential three-step methylation of xanthine derivatives at positions 7-N, 3-N, and 1-N. The protein 7-methylxanthine methyltransferase (designated as CaMXMT) catalyzes the second step to produce theobromine.


Pssm-ID: 460946  Cd Length: 326  Bit Score: 62.19  E-value: 1.41e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240256075   46 FPMSYLHVAVSSRVLHILSKVPEKVV-ENG--WNKRKAWIEG-SDRQVLMGYAEQADKDLVDFLAepCR 110
Cdd:pfam03492 103 FPSNSLHFVHSSYSLHWLSQVPEGLEdKNSpaLNKGNIYISGtSPPEVVKAYLRQFQKDFSLFLK--AR 169
PLN02668 PLN02668
indole-3-acetate carboxyl methyltransferase
 32-105 3.27e-06

indole-3-acetate carboxyl methyltransferase


Pssm-ID: 178273  Cd Length: 386  Bit Score: 44.09  E-value: 3.27e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 240256075  32 YRHAPLPRNIFGPMFPMSYLHVAVSSRVLHILSKVPEKVVEN---GWNKRKAWIEGSDRQVLMGYAEQADKDLVDFL 105
Cdd:PLN02668 144 YFAAGVPGSFYRRLFPARSIDVFHSAFSLHWLSQVPESVTDKrsaAYNKGRVFIHGASESTANAYKRQFQADLAGFL 220
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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