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Conserved domains on  [gi|15237011|ref|NP_195272|]
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plant intracellular ras group-related LRR 4 [Arabidopsis thaliana]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
200-490 1.08e-40

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 152.01  E-value: 1.08e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 200 NDGEKLSLIKLASLIEVSAKKATQEINLQNKLTEQLEWLPDSLGKLSSLTSLDLSENHIVVLPNTIGGLSSLTKLDLHSN 279
Cdd:COG4886   4 LLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLS 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 280 RIGQLPESIGELLNLVYLNLGSNQlsslpsAFSRLVRLEELDLSCNNLPILPESIGSLVSLKKLDVETNDIEEIPYSIGG 359
Cdd:COG4886  84 LLLLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGN 157

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 360 CSSLIELRADYNKLKALPEAIGKITTLEILSVRYNNIRQLPTTMSSLASLKELDVSFNELESVPESLCFATTLVKLNIGN 439
Cdd:COG4886 158 LTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSN 237

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|.
gi 15237011 440 NfaDMVSLPrSIGNLEMLEELDISNNQIRVLPDSFKmLTKLRVFRAQENPL 490
Cdd:COG4886 238 N--QLTDLP-ELGNLTNLEELDLSNNQLTDLPPLAN-LTNLKTLDLSNNQL 284
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
200-490 1.08e-40

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 152.01  E-value: 1.08e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 200 NDGEKLSLIKLASLIEVSAKKATQEINLQNKLTEQLEWLPDSLGKLSSLTSLDLSENHIVVLPNTIGGLSSLTKLDLHSN 279
Cdd:COG4886   4 LLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLS 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 280 RIGQLPESIGELLNLVYLNLGSNQlsslpsAFSRLVRLEELDLSCNNLPILPESIGSLVSLKKLDVETNDIEEIPYSIGG 359
Cdd:COG4886  84 LLLLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGN 157

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 360 CSSLIELRADYNKLKALPEAIGKITTLEILSVRYNNIRQLPTTMSSLASLKELDVSFNELESVPESLCFATTLVKLNIGN 439
Cdd:COG4886 158 LTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSN 237

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|.
gi 15237011 440 NfaDMVSLPrSIGNLEMLEELDISNNQIRVLPDSFKmLTKLRVFRAQENPL 490
Cdd:COG4886 238 N--QLTDLP-ELGNLTNLEELDLSNNQLTDLPPLAN-LTNLKTLDLSNNQL 284
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
272-513 2.51e-18

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 88.60  E-value: 2.51e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  272 TKLDLHSNRIGQLPESIGEllNLVYLNLGSNQLSSLPSAFSrlVRLEELDLSCNNLPILPESIGSlvSLKKLDVETNDIE 351
Cdd:PRK15370 181 TELRLKILGLTTIPACIPE--QITTLILDNNELKSLPENLQ--GNIKTLYANSNQLTSIPATLPD--TIQEMELSINRIT 254

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  352 EIPYSIGgcSSLIELRADYNKLKALPEAIGKitTLEILSVRYNNIRQLPTTMSSlaSLKELDVSFNELESVPESLcfATT 431
Cdd:PRK15370 255 ELPERLP--SALQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTLPAHLPS--GITHLNVQSNSLTALPETL--PPG 326

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  432 LVKLNIGNNfaDMVSLPRSIGnlEMLEELDISNNQIRVLPDSF-KMLTKLRVFRaqeNPLHIPPRDIAekgpqAVVQYM- 509
Cdd:PRK15370 327 LKTLEAGEN--ALTSLPASLP--PELQVLDVSKNQITVLPETLpPTITTLDVSR---NALTNLPENLP-----AALQIMq 394


                 ....*..
gi 15237011  510 ---NDLV 513
Cdd:PRK15370 395 asrNNLV 401
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 268-490 2.93e-10

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 60.18  E-value: 2.93e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 268 LSSLTKLDLHSNRIgqlpESIGELL---NLVYLNLGSNQLSSLPSaFSRLVRLEELDLSCNNLPILpESIGSLVSLKKLD 344
Cdd:cd21340   1 LKRITHLYLNDKNI----TKIDNLSlckNLKVLYLYDNKITKIEN-LEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLY 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 345 VETNDIEEIPySIGGCSSLIELRADYNKLkALPEAIgkitTLEilsvrynnirqlPTTMSSLA-SLKELDVSfnelesvp 423
Cdd:cd21340  75 LGGNRISVVE-GLENLTNLEELHIENQRL-PPGEKL----TFD------------PRSLAALSnSLRVLNIS-------- 128

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 424 eslcfattlvklniGNNFADMvslpRSIGNLEMLEELDISNNQIR---VLPDSFKMLTKLRVFRAQENPL 490
Cdd:cd21340 129 --------------GNNIDSL----EPLAPLRNLEQLDASNNQISdleELLDLLSSWPSLRELDLTGNPV 180
LRR_8 pfam13855
Leucine rich repeat;
269-327 1.26e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 54.07  E-value: 1.26e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15237011   269 SSLTKLDLHSNRIGQL-PESIGELLNLVYLNLGSNQLSSL-PSAFSRLVRLEELDLSCNNL 327
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
200-490 1.08e-40

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 152.01  E-value: 1.08e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 200 NDGEKLSLIKLASLIEVSAKKATQEINLQNKLTEQLEWLPDSLGKLSSLTSLDLSENHIVVLPNTIGGLSSLTKLDLHSN 279
Cdd:COG4886   4 LLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLS 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 280 RIGQLPESIGELLNLVYLNLGSNQlsslpsAFSRLVRLEELDLSCNNLPILPESIGSLVSLKKLDVETNDIEEIPYSIGG 359
Cdd:COG4886  84 LLLLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGN 157

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 360 CSSLIELRADYNKLKALPEAIGKITTLEILSVRYNNIRQLPTTMSSLASLKELDVSFNELESVPESLCFATTLVKLNIGN 439
Cdd:COG4886 158 LTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSN 237

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|.
gi 15237011 440 NfaDMVSLPrSIGNLEMLEELDISNNQIRVLPDSFKmLTKLRVFRAQENPL 490
Cdd:COG4886 238 N--QLTDLP-ELGNLTNLEELDLSNNQLTDLPPLAN-LTNLKTLDLSNNQL 284
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
166-517 1.13e-40

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 152.01  E-value: 1.13e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 166 DSFVTKSKPSSLYSDGFAAPPRRPQILDSTLTTGNDGEKLSLIKLASLIEVSAKKATQEINLQNKLTEQLEWLPDSLGKL 245
Cdd:COG4886  33 LLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNL 112

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 246 SSLTSLDLSENHIVVLPNTIGGLSSLTKLDLHSNRIGQLPESIGELLNLVYLNLGSNQLSSLPSAFSRLVRLEELDLSCN 325
Cdd:COG4886 113 TNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNN 192

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 326 NLPILPESIGSLVSLKKLDVETNDIEEIPYSIGGCSSLIELRADYNKLKALPEaIGKITTLEILSVRYNNIRQLPTTmSS 405
Cdd:COG4886 193 QITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPE-LGNLTNLEELDLSNNQLTDLPPL-AN 270

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 406 LASLKELDVSFNELESVpeslcfatTLVKLNIGNNFADMVSLPRSIGNLEMLEELDISNNQIRVLPDSFKMLTKLRVFRA 485
Cdd:COG4886 271 LTNLKTLDLSNNQLTDL--------KLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLAL 342

                       330       340       350
                ....*....|....*....|....*....|..
gi 15237011 486 QENPLHIPPRDIAEKGPQAVVQYMNDLVETRN 517
Cdd:COG4886 343 SLSLLALLTLLLLLNLLSLLLTLLLTLGLLGL 374
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
268-498 1.30e-21

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 97.31  E-value: 1.30e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 268 LSSLTKLDLHSNRIGQLPESIGELLNLVYLNLGSNQLSSLPSAFSRLVRLEELDLSCNNLPILPESIGSLVSLKKLDVET 347
Cdd:COG4886   3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 348 NDIEEIPYSIGGCSSLIELRADYNklkalpEAIGKITTLEILSVRYNNIRQLPTTMSSLASLKELDVSFNELESVPESLC 427
Cdd:COG4886  83 SLLLLGLTDLGDLTNLTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLG 156

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15237011 428 FATTLVKLNIGNNfaDMVSLPRSIGNLEMLEELDISNNQIRVLPDSFKMLTKLRVFRAQENPLHIPPRDIA 498
Cdd:COG4886 157 NLTNLKSLDLSNN--QLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLA 225
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
272-513 2.51e-18

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 88.60  E-value: 2.51e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  272 TKLDLHSNRIGQLPESIGEllNLVYLNLGSNQLSSLPSAFSrlVRLEELDLSCNNLPILPESIGSlvSLKKLDVETNDIE 351
Cdd:PRK15370 181 TELRLKILGLTTIPACIPE--QITTLILDNNELKSLPENLQ--GNIKTLYANSNQLTSIPATLPD--TIQEMELSINRIT 254

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  352 EIPYSIGgcSSLIELRADYNKLKALPEAIGKitTLEILSVRYNNIRQLPTTMSSlaSLKELDVSFNELESVPESLcfATT 431
Cdd:PRK15370 255 ELPERLP--SALQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTLPAHLPS--GITHLNVQSNSLTALPETL--PPG 326

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  432 LVKLNIGNNfaDMVSLPRSIGnlEMLEELDISNNQIRVLPDSF-KMLTKLRVFRaqeNPLHIPPRDIAekgpqAVVQYM- 509
Cdd:PRK15370 327 LKTLEAGEN--ALTSLPASLP--PELQVLDVSKNQITVLPETLpPTITTLDVSR---NALTNLPENLP-----AALQIMq 394


                 ....*..
gi 15237011  510 ---NDLV 513
Cdd:PRK15370 395 asrNNLV 401
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 261-467 4.57e-18

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 87.98  E-value: 4.57e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  261 LPNTIGGLSSLTKLDL-HSNRIGQLPESIGELLNLVYLNLGSNQLS-SLPSAFSRLVRLEELDLSCNNLP-ILPESIGSL 337
Cdd:PLN00113 228 IPYEIGGLTSLNHLDLvYNNLTGPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSgEIPELVIQL 307

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  338 VSLKKLDVETNDIE-EIPYSIGGCSSLIELRADYNKLKA-LPEAIGKITTLEILSVRYNNIR-QLPTTMSSLASLKELDV 414
Cdd:PLN00113 308 QNLEILHLFSNNFTgKIPVALTSLPRLQVLQLWSNKFSGeIPKNLGKHNNLTVLDLSTNNLTgEIPEGLCSSGNLFKLIL 387

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 15237011  415 SFNELES-VPESL--CFATTLVKLNiGNNFADmvSLPRSIGNLEMLEELDISNNQI 467
Cdd:PLN00113 388 FSNSLEGeIPKSLgaCRSLRRVRLQ-DNSFSG--ELPSEFTKLPLVYFLDISNNNL 440
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 229-493 1.14e-16

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 83.74  E-value: 1.14e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  229 NKLTEQLewlPDSLGKLSSLTSLDLSENHIV-VLPNTIGGLSSLTKLDLHSNRI-GQLPESIGELLNLVYLNLGSNQLS- 305
Cdd:PLN00113 246 NNLTGPI---PSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLsGEIPELVIQLQNLEILHLFSNNFTg 322

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  306 SLPSAFSRLVRLE------------------------ELDLSCNNLP-ILPESIGSLVSLKKLDVETNDIE-EIPYSIGG 359
Cdd:PLN00113 323 KIPVALTSLPRLQvlqlwsnkfsgeipknlgkhnnltVLDLSTNNLTgEIPEGLCSSGNLFKLILFSNSLEgEIPKSLGA 402

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  360 CSSLIELRADYNKLKA-LPEAIGKITTLEILSVRYNNIR-QLPTTMSSLASLKELDVSFNE-LESVPESLCfATTLVKLN 436
Cdd:PLN00113 403 CRSLRRVRLQDNSFSGeLPSEFTKLPLVYFLDISNNNLQgRINSRKWDMPSLQMLSLARNKfFGGLPDSFG-SKRLENLD 481

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15237011  437 IGNN-FADMVslPRSIGNLEMLEELDISNNQIR-VLPDSFKMLTKLRVFRAQENPL--HIP 493
Cdd:PLN00113 482 LSRNqFSGAV--PRKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQLsgQIP 540
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 261-480 8.15e-16

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 81.05  E-value: 8.15e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  261 LPNTIGGLSSLTKLDLHSN-RIGQLPESIGELLNLVYLNLGSNQLS-------------------------SLPSAFSRL 314
Cdd:PLN00113 156 IPNDIGSFSSLKVLDLGGNvLVGKIPNSLTNLTSLEFLTLASNQLVgqiprelgqmkslkwiylgynnlsgEIPYEIGGL 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  315 VRLEELDLSCNNL--PIlPESIGSLVSLKKLDVETNDIE-EIPYSIGGCSSLIELRADYNKLKA-LPEAIGKITTLEILS 390
Cdd:PLN00113 236 TSLNHLDLVYNNLtgPI-PSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSGeIPELVIQLQNLEILH 314

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  391 VRYNNIR-QLPTTMSSLASLK------------------------ELDVSFNELES-VPESLCFATTLVKLNIGNNFADM 444
Cdd:PLN00113 315 LFSNNFTgKIPVALTSLPRLQvlqlwsnkfsgeipknlgkhnnltVLDLSTNNLTGeIPEGLCSSGNLFKLILFSNSLEG 394

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 15237011  445 vSLPRSIGNLEMLEELDISNNQIR-VLPDSFkmlTKL 480
Cdd:PLN00113 395 -EIPKSLGACRSLRRVRLQDNSFSgELPSEF---TKL 427
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
228-426 1.74e-14

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 76.66  E-value: 1.74e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  228 QNKLTEQLEWLPDSLgklsslTSLDLSENHIVVLPNTIGglSSLTKLDLHSNRIGQLPESIGEllNLVYLNLGSNQLSSL 307
Cdd:PRK15370 229 SNQLTSIPATLPDTI------QEMELSINRITELPERLP--SALQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTL 298

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  308 PSAFSRlvRLEELDLSCNNLPILPESIGslVSLKKLDVETNDIEEIPYSIGgcSSLIELRADYNKLKALPEAIGKitTLE 387
Cdd:PRK15370 299 PAHLPS--GITHLNVQSNSLTALPETLP--PGLKTLEAGENALTSLPASLP--PELQVLDVSKNQITVLPETLPP--TIT 370

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 15237011  388 ILSVRYNNIRQLPTTMSslASLKELDVSFNELESVPESL 426
Cdd:PRK15370 371 TLDVSRNALTNLPENLP--AALQIMQASRNNLVRLPESL 407
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
223-408 9.07e-14

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 74.35  E-value: 9.07e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  223 QEINLQ-NKLTEQLEWLPDSLgklsslTSLDLSENHIVVLPNTIGglSSLTKLDLHSNRIGQLPESIGEllNLVYLNLGS 301
Cdd:PRK15370 244 QEMELSiNRITELPERLPSAL------QSLDLFHNKISCLPENLP--EELRYLSVYDNSIRTLPAHLPS--GITHLNVQS 313

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  302 NQLSSLPSAFSrlVRLEELDLSCNNLPILPESIGSlvSLKKLDVETNDIEEIPYSIGgcSSLIELRADYNKLKALPEAIG 381
Cdd:PRK15370 314 NSLTALPETLP--PGLKTLEAGENALTSLPASLPP--ELQVLDVSKNQITVLPETLP--PTITTLDVSRNALTNLPENLP 387

                        170       180
                 ....*....|....*....|....*..
gi 15237011  382 kiTTLEILSVRYNNIRQLPTTMSSLAS 408
Cdd:PRK15370 388 --AALQIMQASRNNLVRLPESLPHFRG 412
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 269-465 6.74e-13

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 71.80  E-value: 6.74e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  269 SSLTKLDLHSNRI-GQLPESIGELLNLVYLNLGSNQLS--------------------------SLPSAFsrLVRLEELD 321
Cdd:PLN00113  69 SRVVSIDLSGKNIsGKISSAIFRLPYIQTINLSNNQLSgpipddifttssslrylnlsnnnftgSIPRGS--IPNLETLD 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  322 LSCNNLP-ILPESIGSLVSLKKLDVETNDIE-EIPYSIGGCSSLIELRADYNKLKA-LPEAIGKITTLEILSVRYNNIR- 397
Cdd:PLN00113 147 LSNNMLSgEIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVGqIPRELGQMKSLKWIYLGYNNLSg 226

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  398 QLPTTMSSLASLKELDVSFNELE-SVPESLCFATTLVKLNI-GNNFADmvSLPRSIGNLEMLEELDISNN 465
Cdd:PLN00113 227 EIPYEIGGLTSLNHLDLVYNNLTgPIPSSLGNLKNLQYLFLyQNKLSG--PIPPSIFSLQKLISLDLSDN 294
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 238-440 1.27e-10

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 64.48  E-value: 1.27e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  238 LPDSLGKLSSLTSLDLSENHIV-VLPNTIGGLSSLTKLDLHSNRI-GQLPESIGELLNLVYLNLGSNQLS-SLPSAFsRL 314
Cdd:PLN00113 396 IPKSLGACRSLRRVRLQDNSFSgELPSEFTKLPLVYFLDISNNNLqGRINSRKWDMPSLQMLSLARNKFFgGLPDSF-GS 474

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  315 VRLEELDLSCNNLP-ILPESIGSLVSLKKLDVETNDIE-EIPYSIGGCSSLIELRADYNKLKAlpeaigkittleilsvr 392
Cdd:PLN00113 475 KRLENLDLSRNQFSgAVPRKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQLSG----------------- 537

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 15237011  393 ynnirQLPTTMSSLASLKELDVSFNELE-SVPESLCFATTLVKLNIGNN 440
Cdd:PLN00113 538 -----QIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHN 581
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 268-490 2.93e-10

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 60.18  E-value: 2.93e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 268 LSSLTKLDLHSNRIgqlpESIGELL---NLVYLNLGSNQLSSLPSaFSRLVRLEELDLSCNNLPILpESIGSLVSLKKLD 344
Cdd:cd21340   1 LKRITHLYLNDKNI----TKIDNLSlckNLKVLYLYDNKITKIEN-LEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLY 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 345 VETNDIEEIPySIGGCSSLIELRADYNKLkALPEAIgkitTLEilsvrynnirqlPTTMSSLA-SLKELDVSfnelesvp 423
Cdd:cd21340  75 LGGNRISVVE-GLENLTNLEELHIENQRL-PPGEKL----TFD------------PRSLAALSnSLRVLNIS-------- 128

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 424 eslcfattlvklniGNNFADMvslpRSIGNLEMLEELDISNNQIR---VLPDSFKMLTKLRVFRAQENPL 490
Cdd:cd21340 129 --------------GNNIDSL----EPLAPLRNLEQLDASNNQISdleELLDLLSSWPSLRELDLTGNPV 180
LRR_8 pfam13855
Leucine rich repeat;
269-327 1.26e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 54.07  E-value: 1.26e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15237011   269 SSLTKLDLHSNRIGQL-PESIGELLNLVYLNLGSNQLSSL-PSAFSRLVRLEELDLSCNNL 327
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 254-435 7.09e-09

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 56.33  E-value: 7.09e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 254 SENHIVVLPNtIGGLSSLTKLDLHSNRIGQLpESIGELLNLVYLNLGSNQLSSLPSaFSRLVRLEELDLSCNNLPILpES 333
Cdd:cd21340  10 NDKNITKIDN-LSLCKNLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQIEKIEN-LENLVNLKKLYLGGNRISVV-EG 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 334 IGSLVSLKKLDVETNDIEEipysigGCSSLIELRAdynkLKALPEaigkitTLEILSVRYNNIRQLpTTMSSLASLKELD 413
Cdd:cd21340  86 LENLTNLEELHIENQRLPP------GEKLTFDPRS----LAALSN------SLRVLNISGNNIDSL-EPLAPLRNLEQLD 148

                       170       180
                ....*....|....*....|..
gi 15237011 414 VSFNELESVPESLCFATTLVKL 435
Cdd:cd21340 149 ASNNQISDLEELLDLLSSWPSL 170
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
271-490 8.17e-09

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 58.25  E-value: 8.17e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  271 LTKLDLHSNRIGQLPESIGELLNLvylNLGSNQLSSLPSAFSRLVRLEELDLSCNNLPILPEsigslvSLKKLDVETNDI 350
Cdd:PRK15387 244 LRTLEVSGNQLTSLPVLPPGLLEL---SIFSNPLTHLPALPSGLCKLWIFGNQLTSLPVLPP------GLQELSVSDNQL 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  351 EEIPysiGGCSSLIELRADYNKLKALPEAigkITTLEILSVRYNNIRQLPTTMSSL-----------------ASLKELD 413
Cdd:PRK15387 315 ASLP---ALPSELCKLWAYNNQLTSLPTL---PSGLQELSVSDNQLASLPTLPSELyklwaynnrltslpalpSGLKELI 388

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15237011  414 VSFNELESVPeslCFATTLVKLNI-GNNFADMVSLPRSignlemLEELDISNNQIRVLPDSFKMLTKLRVFRAQENPL 490
Cdd:PRK15387 389 VSGNRLTSLP---VLPSELKELMVsGNRLTSLPMLPSG------LLSLSVYRNQLTRLPESLIHLSSETTVNLEGNPL 457
LRR_8 pfam13855
Leucine rich repeat;
293-350 1.05e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 51.76  E-value: 1.05e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011   293 NLVYLNLGSNQLSSL-PSAFSRLVRLEELDLSCNNLPIL-PESIGSLVSLKKLDVETNDI 350
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 270-464 7.17e-08

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 55.65  E-value: 7.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011   270 SLTKLDLHSNRIGQLPESIGELLNLVYLNL-GSNQLSSLPSaFSRLVRLEELDLS-CNNLPILPESIGSLVSLKKLDVET 347
Cdd:PLN03210  612 NLVKLQMQGSKLEKLWDGVHSLTGLRNIDLrGSKNLKEIPD-LSMATNLETLKLSdCSSLVELPSSIQYLNKLEDLDMSR 690

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011   348 ND-IEEIPYSI----------GGCSslielradynKLKALPEAIGKITTLEILSVrynNIRQLPTTMS-------SLASL 409
Cdd:PLN03210  691 CEnLEILPTGInlkslyrlnlSGCS----------RLKSFPDISTNISWLDLDET---AIEEFPSNLRlenldelILCEM 757

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 15237011   410 KELDVSFNELESVPESLCFATTLVKLNIGNNfADMVSLPRSIGNLEMLEELDISN 464
Cdd:PLN03210  758 KSEKLWERVQPLTPLMTMLSPSLTRLFLSDI-PSLVELPSSIQNLHKLEHLEIEN 811
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
297-499 2.09e-07

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 54.01  E-value: 2.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  297 LNLGSNQLSSLPSAF-SRLVRLEELDLSCNNLPILPESigslvsLKKLDVETNDIEEIPYSIGGcssLIELRADYNKLKA 375
Cdd:PRK15387 206 LNVGESGLTTLPDCLpAHITTLVIPDNNLTSLPALPPE------LRTLEVSGNQLTSLPVLPPG---LLELSIFSNPLTH 276

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  376 LPEAIGKITTLEILSVRYNNIRQLPttmsslASLKELDVSFNELESVPeslCFATTLVKLNIGNNfaDMVSLPRSIGNLE 455
Cdd:PRK15387 277 LPALPSGLCKLWIFGNQLTSLPVLP------PGLQELSVSDNQLASLP---ALPSELCKLWAYNN--QLTSLPTLPSGLQ 345

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 15237011  456 mleELDISNNQIRVLPDSFKMLTKLRVFRAQENPLHIPPRDIAE 499
Cdd:PRK15387 346 ---ELSVSDNQLASLPTLPSELYKLWAYNNRLTSLPALPSGLKE 386
PLN03150 PLN03150
hypothetical protein; Provisional
 282-359 2.12e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 53.67  E-value: 2.12e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  282 GQLPESIGELLNLVYLNLGSNQL-SSLPSAFSRLVRLEELDLSCNNLP-ILPESIGSLVSLKKLDVETNDIE-EIPYSIG 358
Cdd:PLN03150 432 GFIPNDISKLRHLQSINLSGNSIrGNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLSgRVPAALG 511


                 .
gi 15237011  359 G 359
Cdd:PLN03150 512 G 512
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 256-348 7.77e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 50.17  E-value: 7.77e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 256 NHIVVLPNtIGGLSSLTKLDLHSNRIGQL----------------------------PESIGELLN-LVYLNLGSNQLSS 306
Cdd:cd21340  56 NQIEKIEN-LENLVNLKKLYLGGNRISVVeglenltnleelhienqrlppgekltfdPRSLAALSNsLRVLNISGNNIDS 134

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 15237011 307 LpSAFSRLVRLEELDLSCNNL----PILpESIGSLVSLKKLDVETN 348
Cdd:cd21340 135 L-EPLAPLRNLEQLDASNNQIsdleELL-DLLSSWPSLRELDLTGN 178
PLN03150 PLN03150
hypothetical protein; Provisional
 238-316 2.83e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 50.20  E-value: 2.83e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  238 LPDSLGKLSSLTSLDLSENHIV-VLPNTIGGLSSLTKLDLHSNRI-GQLPESIGELLNLVYLNLGSNQLSS-LPSAF-SR 313
Cdd:PLN03150 434 IPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFnGSIPESLGQLTSLRILNLNGNSLSGrVPAALgGR 513


                 ...
gi 15237011  314 LVR 316
Cdd:PLN03150 514 LLH 516
PLN03150 PLN03150
hypothetical protein; Provisional
 376-441 6.05e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 49.04  E-value: 6.05e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15237011  376 LPEAIGKITTLEILSVRYNNIR-QLPTTMSSLASLKELDVSFNELE-SVPESLCFATTLVKLNIGNNF 441
Cdd:PLN03150 434 IPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNS 501
PLN03150 PLN03150
hypothetical protein; Provisional
 330-394 1.10e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 48.27  E-value: 1.10e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15237011  330 LPESIGSLVSLKKLDVETNDIE-EIPYSIGGCSSLIELRADYNKLK-ALPEAIGKITTLEILSVRYN 394
Cdd:PLN03150 434 IPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGN 500
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
269-419 1.11e-05

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 48.23  E-value: 1.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011  269 SSLTKLDLHSNRIGQLPESIGELLNLvylNLGSNQLSSLPSAFSRLVRLEELDLSCNNLPILPEsigslvSLKKLDVETN 348
Cdd:PRK15387 322 SELCKLWAYNNQLTSLPTLPSGLQEL---SVSDNQLASLPTLPSELYKLWAYNNRLTSLPALPS------GLKELIVSGN 392

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15237011  349 DIEEIPYSIggcSSLIELRADYNKLKALPEAIGKITTleiLSVRYNNIRQLPTTMSSLASLKELDVSFNEL 419
Cdd:PRK15387 393 RLTSLPVLP---SELKELMVSGNRLTSLPMLPSGLLS---LSVYRNQLTRLPESLIHLSSETTVNLEGNPL 457
LRR_8 pfam13855
Leucine rich repeat;
256-304 2.66e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.04  E-value: 2.66e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 15237011   256 NHIVVL-PNTIGGLSSLTKLDLHSNRIGQL-PESIGELLNLVYLNLGSNQL 304
Cdd:pfam13855  11 NRLTSLdDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 131-440 2.97e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 43.24  E-value: 2.97e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 131 PLPPATTTAARSDSQSSLNFSERAPVRPKDMVSRDDSFVTKSKPSSLysdgFAAPPRRPQI---LDSTLTT--GNDGE-- 203
Cdd:COG5238  88 QLLVVDWEGAEEVSPVALAETATAVATPPPDLRRIMAKTLEDSLILY----LALPRRINLIqvlKDPLGGNavHLLGLaa 163

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 204 KLSLIKLASLIEVSAKKATQEINLQNKLTEQ--LEWLPDSLGKLSSLTSLDLSENHI-----VVLPNTIGGLSSLTKLDL 276
Cdd:COG5238 164 RLGLLAAISMAKALQNNSVETVYLGCNQIGDegIEELAEALTQNTTVTTLWLKRNPIgdegaEILAEALKGNKSLTTLDL 243

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 277 HSNRIG-QLPESIGELL----NLVYLNLGSNQLS-----SLPSAFSRLVRLEELDLSCNNlpilpesigslvslkkldve 346
Cdd:COG5238 244 SNNQIGdEGVIALAEALknntTVETLYLSGNQIGaegaiALAKALQGNTTLTSLDLSVNR-------------------- 303

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 347 tndieeipysIGGCSSLielradynklkALPEAIGKITTLEILSVRYNNIRQ-----LPTTMSSLASLKELDVSFNEL-- 419
Cdd:COG5238 304 ----------IGDEGAI-----------ALAEGLQGNKTLHTLNLAYNGIGAqgaiaLAKALQENTTLHSLDLSDNQIgd 362

                       330       340
                ....*....|....*....|....
gi 15237011 420 ---ESVPESLCFATTLVKLNIGNN 440
Cdd:COG5238 363 egaIALAKYLEGNTTLRELNLGKN 386
LRR_8 pfam13855
Leucine rich repeat;
384-467 6.58e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.89  E-value: 6.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011   384 TTLEILSVRYNNIRQL-PTTMSSLASLKELDVSFNELESVPeslcfattlvklnignnfadmvslPRSIGNLEMLEELDI 462
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLS------------------------PGAFSGLPSLRYLDL 56


                  ....*
gi 15237011   463 SNNQI 467
Cdd:pfam13855  57 SGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 269-419 8.46e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 41.57  E-value: 8.46e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 269 SSLTKLDLHSNRIGQLP-----ESIGEL-LNLVYLNLGSNQLSS-----LPSAFSRLVRLEELDLSCNNL-----PILPE 332
Cdd:cd00116 108 SSLQELKLNNNGLGDRGlrllaKGLKDLpPALEKLVLGRNRLEGasceaLAKALRANRDLKELNLANNGIgdagiRALAE 187

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237011 333 SIGSLVSLKKLDVETNDIEEIpysigGCSSLIELRADYNKLKAL----------------PEAIGKITTLEILSVRYNNI 396
Cdd:cd00116 188 GLKANCNLEVLDLNNNGLTDE-----GASALAETLASLKSLEVLnlgdnnltdagaaalaSALLSPNISLLTLSLSCNDI 262

                       170       180
                ....*....|....*....|....*...
gi 15237011 397 -----RQLPTTMSSLASLKELDVSFNEL 419
Cdd:cd00116 263 tddgaKDLAEVLAEKESLLELDLRGNKF 290
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 293-327 1.46e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 36.45  E-value: 1.46e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 15237011   293 NLVYLNLGSNQLSSLPsAFSRLVRLEELDLSCNNL 327
Cdd:pfam12799   2 NLEVLDLSNNQITDIP-PLAKLPNLETLDLSGNNK 35
LRR_8 pfam13855
Leucine rich repeat;
430-490 1.89e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 36.73  E-value: 1.89e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15237011   430 TTLVKLNIGNNFADMVSlPRSIGNLEMLEELDISNNQIRVL-PDSFKMLTKLRVFRAQENPL 490
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLD-DGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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