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HECT ubiquitin protein ligase family protein KAK [Arabidopsis thaliana]
Protein Classification
HECTc domain-containing protein ( domain architecture ID 13416457 )
HECTc domain-containing protein
List of domain hits
Name
Accession
Description
Interval
E-value
HECTc
cd00078 HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
1380-1789
2.07e-123
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.
Pssm-ID: 238033 [Multi-domain]
Cd Length: 352
Bit Score: 391.93
E-value: 2.07e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1380 Q K VR V S R N RIL DS A AKVMEMY SS Q -- K A VLEVE YF GE V G TG - L G P T L EF Y TL L S HD L QKA S L G MW R SSSG D KV smqigrd 1456
Cdd:cd00078 1 L K IT V R R D RIL ED A LRQLSKV SS S dl K K VLEVE FV GE E G ID a G G V T R EF F TL V S KE L FNP S Y G LF R YTPD D SG ------- 73
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1457 eiedgkpsaanrdivlapl G L F P R P WPSTAD iseggqfh KVIEY FR L LGR VMA KAL QD GRLLD V P L S T AFYK LI LG QE L D 1536
Cdd:cd00078 74 ------------------- L L Y P N P SSFADE -------- DHLKL FR F LGR LLG KAL YE GRLLD L P F S R AFYK KL LG KP L S 126
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1537 L H D IVLF D A EL G K T L Q EL R vvvarkhylegvgg DN SSTIS DL C L R gcri EDLS L EFTLP G YP -- E YILRSG D EI V DIT N L 1614
Cdd:cd00078 127 L E D LEEL D P EL Y K S L K EL L -------------- DN DGDED DL E L T ---- FTIE L DSSFG G AV tv E LKPGGR D IP V TNE N K 188
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1615 EEY IS L V VD ATVKR G VTR Q I EAFR S GF NQ V FDITS L QI FTP S EL DY L L CG RRE l WEV E T L AEHIKFDH GY NAK SP A I --- 1691
Cdd:cd00078 189 EEY VD L Y VD YRLNK G IEE Q V EAFR D GF SE V IPEEL L SL FTP E EL EL L I CG SED - IDL E D L KKNTEYKG GY SSD SP T I qwf 267
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1692 INIMGEL T ADQQRA F C QFVTG AP RLP P GG L A V LNPK L TI V R KH S S tssaaangagaseta DD D LP SVM TC A N Y LKLPPYS 1771
Cdd:cd00078 268 WEVLESF T NEERKK F L QFVTG SS RLP V GG F A D LNPK F TI R R VG S P --------------- DD R LP TAH TC F N L LKLPPYS 332
410
....*....|....*...
gi 30692023 1772 T KEI MYK KLLYAINEG Q G 1789
Cdd:cd00078 333 S KEI LRE KLLYAINEG A G 350
SRP1 super family
cl34886 Karyopherin (importin) alpha [Intracellular trafficking and secretion];
138-538
1.55e-04
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
COG5064 :Pssm-ID: 227396 [Multi-domain]
Cd Length: 526
Bit Score: 46.42
E-value: 1.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 138 Q VE A LTQLCEM LS IG T EDSLSTFSVDSF VP VL V GLLNHESNPDIMLL AA R ALT HLCDVLPSSCAA VV HY GAV SCLVAR L L 217
Cdd:COG5064 88 Q LQ A VYKFRKL LS KE T SPPIQPVIDAGV VP RF V EFMDEIQRDMLQFE AA W ALT NIASGTTQQTKV VV DA GAV PLFIQL L S 167
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 218 TI E y M D LA EQ SLQ AL KK I SQEHP t A C ---- L RA GAL MAV L SY L DFFSTGVQ -- R V A LS T AA N M C K - K L P SDASDYVME A V 290
Cdd:COG5064 168 ST E - D D VR EQ AVW AL GN I AGDSE - G C rdyv L QC GAL EPL L GL L LSSAIHIS ml R N A TW T LS N L C R g K N P PPDWSNISQ A L 245
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 291 P L L TN L LQYH D SK VL EY A SICLTRIAEAFA pyp EK LDELCNH G LVTQAAS L I S tsnsgggqa SL S VSTY T GLI R LLSTCA 370
Cdd:COG5064 246 P I L AK L IYSR D PE VL VD A CWAISYLSDGPN --- EK IQAVLDV G IPGRLVE L L S --------- HE S AKIQ T PAL R SVGNIV 313
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 371 S GS PL gfrtllllgissi LKDILLGS G vs A NASVSPA LS R P ADQ I ----- YE I V N LA ------------ NE L L PPL peg V 433
Cdd:COG5064 314 T GS DD ------------- QTQVIINC G -- A LKAFRSL LS S P KEN I rkeac WT I S N IT agnteqiqavid AN L I PPL --- I 375
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 434 IS L PTSTNALV K GS C QKK S SPSTS G - KQE DI LK ------- I S P REK LL GDQPELLQQFG LD LL ----------------- 488
Cdd:COG5064 376 HL L SSAEYKIK K EA C WAI S NATSG G l NRP DI IR ylvsqgf I K P LCD LL DVVDNKIIEVA LD AI enilkvgeqdrlrygkn 455
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30692023 489 ---- P V L V QIY G --------- S SVN G TI RH K CL S V I G K lm Y F SSSEMIQS L IGD T NISS F LA G 538
Cdd:COG5064 456 iniy A V Y V EKA G gmdaihglq D SVN R TI YD K AY S I I E K -- F F GEEDAVDE L APE T AGNT F TF G 516
Name
Accession
Description
Interval
E-value
HECTc
cd00078 HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
1380-1789
2.07e-123
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.
Pssm-ID: 238033 [Multi-domain]
Cd Length: 352
Bit Score: 391.93
E-value: 2.07e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1380 Q K VR V S R N RIL DS A AKVMEMY SS Q -- K A VLEVE YF GE V G TG - L G P T L EF Y TL L S HD L QKA S L G MW R SSSG D KV smqigrd 1456
Cdd:cd00078 1 L K IT V R R D RIL ED A LRQLSKV SS S dl K K VLEVE FV GE E G ID a G G V T R EF F TL V S KE L FNP S Y G LF R YTPD D SG ------- 73
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1457 eiedgkpsaanrdivlapl G L F P R P WPSTAD iseggqfh KVIEY FR L LGR VMA KAL QD GRLLD V P L S T AFYK LI LG QE L D 1536
Cdd:cd00078 74 ------------------- L L Y P N P SSFADE -------- DHLKL FR F LGR LLG KAL YE GRLLD L P F S R AFYK KL LG KP L S 126
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1537 L H D IVLF D A EL G K T L Q EL R vvvarkhylegvgg DN SSTIS DL C L R gcri EDLS L EFTLP G YP -- E YILRSG D EI V DIT N L 1614
Cdd:cd00078 127 L E D LEEL D P EL Y K S L K EL L -------------- DN DGDED DL E L T ---- FTIE L DSSFG G AV tv E LKPGGR D IP V TNE N K 188
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1615 EEY IS L V VD ATVKR G VTR Q I EAFR S GF NQ V FDITS L QI FTP S EL DY L L CG RRE l WEV E T L AEHIKFDH GY NAK SP A I --- 1691
Cdd:cd00078 189 EEY VD L Y VD YRLNK G IEE Q V EAFR D GF SE V IPEEL L SL FTP E EL EL L I CG SED - IDL E D L KKNTEYKG GY SSD SP T I qwf 267
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1692 INIMGEL T ADQQRA F C QFVTG AP RLP P GG L A V LNPK L TI V R KH S S tssaaangagaseta DD D LP SVM TC A N Y LKLPPYS 1771
Cdd:cd00078 268 WEVLESF T NEERKK F L QFVTG SS RLP V GG F A D LNPK F TI R R VG S P --------------- DD R LP TAH TC F N L LKLPPYS 332
410
....*....|....*...
gi 30692023 1772 T KEI MYK KLLYAINEG Q G 1789
Cdd:cd00078 333 S KEI LRE KLLYAINEG A G 350
HECT
pfam00632 HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl ...
1427-1794
1.56e-97
HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl Terminus.
Pssm-ID: 459880
Cd Length: 304
Bit Score: 316.86
E-value: 1.56e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1427 TLLS HD L QKASL G MWRSSSG D KVSMQ igrdeiedgkpsaanrdivlaplglfpr PW PS TADIS eggq FHKVIE YF RL LG R 1506
Cdd:pfam00632 1 TLLS KE L FDPNY G LFEYETE D DRTYW ---------------------------- FN PS SSESP ---- DLELLD YF KF LG K 48
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1507 VMA KA LQD G R LLD V P LSTA FYK LI LG QE L D L H D IVLF D A EL G K T L QE L RVVVARKH ylegvggdnsstisdlclrgcri E 1586
Cdd:pfam00632 49 LLG KA IYN G I LLD L P FPPF FYK KL LG EP L T L E D LESI D P EL Y K S L KS L LNMDNDDD ----------------------- E 105
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1587 DL S L E FT L P -- G YPEY I -- LRS G DE I - V DIT N L EEYI S L V VD ATVKRGVTR Q I EAFR S GF NQ V FDITS L QI FTP S EL DY L 1661
Cdd:pfam00632 106 DL G L T FT I P vf G ESKT I el IPN G RN I p V TNE N K EEYI R L Y VD YRLNKSIEP Q L EAFR K GF YS V IPKEA L SL FTP E EL EL L 185
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1662 L CG RR E l WE VE T L AEHIKF D H GY NAK SP A I IN --- I MG E LTAD Q Q R A F CQ FVTG AP RLP P GG LAV L n PK L TIVRK HS sts 1738
Cdd:pfam00632 186 I CG SP E - ID VE D L KKNTEY D G GY TKN SP T I QW fwe I LE E FSPE Q R R L F LK FVTG SS RLP V GG FKS L - PK F TIVRK GG --- 260
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 30692023 1739 saaangagase TA DD D LP SVM TC A N Y LKLP P YS T KEI MYK KLL Y AI N EG Q G s F D LS 1794
Cdd:pfam00632 261 ----------- DD DD R LP TAH TC F N R LKLP D YS S KEI LKE KLL I AI E EG E G - F G LS 304
HECTc
smart00119 Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to ...
1403-1789
1.75e-92
Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to E2 enzymes.
Pssm-ID: 214523
Cd Length: 328
Bit Score: 303.39
E-value: 1.75e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1403 Q K A VLE V E YF GE V G - T G L G P T L EF YT LLS HD L QKASL G MW R S S SG D K vsmqigrdeiedgkpsaanrdivlapl G L F P R P 1481
Cdd:smart00119 3 K K R VLE I E FE GE E G l D G G G V T R EF FF LLS KE L FNPDY G LF R Y S PN D Y --------------------------- L L Y P N P 55
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1482 WPST A D iseggqf HKVIE YFR LL GRV MA KAL Q D G RLLD VPLSTA FYK LI LG QELD LHD IVLF D A EL G K T L QE L R vvvark 1561
Cdd:smart00119 56 RSGF A N ------- EEHLS YFR FI GRV LG KAL Y D N RLLD LFFARP FYK KL LG KPVT LHD LESL D P EL Y K S L KW L L ------ 122
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1562 hy L E gvgg DNS S TIS DL C lrgcri EDLS L EFTLPGYPEYI L RS G DEIVDI T -- N LE EY IS LV VDATVKR G VTR Q I EAFR S 1639
Cdd:smart00119 123 -- L N ---- NDT S EEL DL T ------ FSIV L TSEFGQVKVVE L KP G GSNIPV T ee N KK EY VH LV IEYRLNK G IEK Q L EAFR E 190
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1640 GF NQ V FDITS L QI F T P S EL DY L L CG RR E l WE V ET L AEHIKFDH GY N A K S PA I --- INIMGEL T ADQQ R AFC QFVTG AP RL 1716
Cdd:smart00119 191 GF SE V IPENL L KL F D P E EL EL L I CG SP E - ID V DD L KSNTEYKG GY S A N S QT I kwf WEVVESF T NEER R KLL QFVTG SS RL 269
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30692023 1717 P P GG L A V L N PK L TI VRKH S S tssaaangagaseta D DD LP SVM TC A N Y LKLPPYS T KEI MYK KLL Y AINEG Q G 1789
Cdd:smart00119 270 P V GG F A A L S PK F TI RKAG S D --------------- D ER LP TAH TC F N R LKLPPYS S KEI LRE KLL L AINEG K G 327
HUL4
COG5021 Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
1293-1791
1.39e-72
Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 227354 [Multi-domain]
Cd Length: 872
Bit Score: 262.01
E-value: 1.39e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1293 FVNSKLTPK L A R QIQDALALC S GSLPSWCYQLT rac P F L FPFQ TR RQYF Y STA F GLS R - ALNRLQQQQGADGSGSTNERE 1371
Cdd:COG5021 413 TYEDLRREQ L G R ESDESFYVA S NVQQQRASREG --- P L L SGWK TR LNNL Y RFY F VEH R k KTLTKNDSRLGSFISLNKLDI 489
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1372 M RI GRLQ R Q K VRV S RNRILDSAAKVMEMYSSQKA V L E V --- E YFG E V G TG L GP TLE FYTLLSHDLQKAS L GMWR sssgdk 1448
Cdd:COG5021 490 R RI KEDK R R K LFY S LKQKAKIFDPYLHIKVRRDR V F E D syr E IMD E S G DD L KK TLE IEFVGEEGIDAGG L TREW ------ 563
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1449 vs MQIGRD E IEDGKPSA anrd IVLAPLG L FPR P WPSTAD I SE ggqfh KVIE YF RL LGRV MA KA LQ D G R L LDV PL S T AFYK 1528
Cdd:COG5021 564 -- LFLLSK E MFNPDYGL ---- FEYITED L YTL P INPLSS I NP ----- EHLS YF KF LGRV IG KA IY D S R I LDV QF S K AFYK 632
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1529 LI LG QELD L H D IVLF D A EL GKT L QE L R vvvarkhylegvgg D N SSTISD L C L R g CRI ED L S LEFTLP gy P E Y I LRSGDEI 1608
Cdd:COG5021 633 KL LG KPVS L V D LESL D P EL YRS L VW L L -------------- N N DIDETI L D L T - FTV ED D S FGESRT -- V E L I PNGRNIS 695
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1609 V DIT N LE EY ISL VVD ATVKRG V TR Q IE AF R SGF NQVFDITS LQIF TP SEL DY L LC G RR E LWEVETLAEHIK f D HGY NAK S 1688
Cdd:COG5021 696 V TNE N KK EY VKK VVD YKLNKR V EK Q FS AF K SGF SEIIPPDL LQIF DE SEL EL L IG G IP E DIDIDDWKSNTA - Y HGY TED S 774
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1689 P A I I --- N I MG E LTADQQRAFC QFVTG AP R L P PG G LAV L NPKLTIVRKHS stssaaanga GASE T A DD D LPS VM TC A N Y L 1765
Cdd:COG5021 775 P I I V wfw E I IS E FDFEERAKLL QFVTG TS R I P IN G FKD L QGSDGVRKFTI ---------- EKGG T D DD R LPS AH TC F N R L 844
490 500
....*....|....*....|....*.
gi 30692023 1766 KLP P YS T KE IMYK KLL Y AINEG Q G SF 1791
Cdd:COG5021 845 KLP E YS S KE KLRS KLL T AINEG A G FG 870
SRP1
COG5064 Karyopherin (importin) alpha [Intracellular trafficking and secretion];
138-538
1.55e-04
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
Pssm-ID: 227396 [Multi-domain]
Cd Length: 526
Bit Score: 46.42
E-value: 1.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 138 Q VE A LTQLCEM LS IG T EDSLSTFSVDSF VP VL V GLLNHESNPDIMLL AA R ALT HLCDVLPSSCAA VV HY GAV SCLVAR L L 217
Cdd:COG5064 88 Q LQ A VYKFRKL LS KE T SPPIQPVIDAGV VP RF V EFMDEIQRDMLQFE AA W ALT NIASGTTQQTKV VV DA GAV PLFIQL L S 167
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 218 TI E y M D LA EQ SLQ AL KK I SQEHP t A C ---- L RA GAL MAV L SY L DFFSTGVQ -- R V A LS T AA N M C K - K L P SDASDYVME A V 290
Cdd:COG5064 168 ST E - D D VR EQ AVW AL GN I AGDSE - G C rdyv L QC GAL EPL L GL L LSSAIHIS ml R N A TW T LS N L C R g K N P PPDWSNISQ A L 245
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 291 P L L TN L LQYH D SK VL EY A SICLTRIAEAFA pyp EK LDELCNH G LVTQAAS L I S tsnsgggqa SL S VSTY T GLI R LLSTCA 370
Cdd:COG5064 246 P I L AK L IYSR D PE VL VD A CWAISYLSDGPN --- EK IQAVLDV G IPGRLVE L L S --------- HE S AKIQ T PAL R SVGNIV 313
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 371 S GS PL gfrtllllgissi LKDILLGS G vs A NASVSPA LS R P ADQ I ----- YE I V N LA ------------ NE L L PPL peg V 433
Cdd:COG5064 314 T GS DD ------------- QTQVIINC G -- A LKAFRSL LS S P KEN I rkeac WT I S N IT agnteqiqavid AN L I PPL --- I 375
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 434 IS L PTSTNALV K GS C QKK S SPSTS G - KQE DI LK ------- I S P REK LL GDQPELLQQFG LD LL ----------------- 488
Cdd:COG5064 376 HL L SSAEYKIK K EA C WAI S NATSG G l NRP DI IR ylvsqgf I K P LCD LL DVVDNKIIEVA LD AI enilkvgeqdrlrygkn 455
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30692023 489 ---- P V L V QIY G --------- S SVN G TI RH K CL S V I G K lm Y F SSSEMIQS L IGD T NISS F LA G 538
Cdd:COG5064 456 iniy A V Y V EKA G gmdaihglq D SVN R TI YD K AY S I I E K -- F F GEEDAVDE L APE T AGNT F TF G 516
HEAT_EZ
pfam13513 HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
263-315
1.71e-03
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.
Pssm-ID: 463906 [Multi-domain]
Cd Length: 55
Bit Score: 38.12
E-value: 1.71e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 30692023 263 V QRV A LSTAANMCKKL P SDASDY V M E AV P L L TN LL QYHDSK V L E Y A SIC L T R I 315
Cdd:pfam13513 3 V REA A ALALGSLAEGG P DLLAPA V P E LL P A L LP LL NDDSDL V R E A A AWA L G R L 55
Name
Accession
Description
Interval
E-value
HECTc
cd00078 HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
1380-1789
2.07e-123
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.
Pssm-ID: 238033 [Multi-domain]
Cd Length: 352
Bit Score: 391.93
E-value: 2.07e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1380 Q K VR V S R N RIL DS A AKVMEMY SS Q -- K A VLEVE YF GE V G TG - L G P T L EF Y TL L S HD L QKA S L G MW R SSSG D KV smqigrd 1456
Cdd:cd00078 1 L K IT V R R D RIL ED A LRQLSKV SS S dl K K VLEVE FV GE E G ID a G G V T R EF F TL V S KE L FNP S Y G LF R YTPD D SG ------- 73
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1457 eiedgkpsaanrdivlapl G L F P R P WPSTAD iseggqfh KVIEY FR L LGR VMA KAL QD GRLLD V P L S T AFYK LI LG QE L D 1536
Cdd:cd00078 74 ------------------- L L Y P N P SSFADE -------- DHLKL FR F LGR LLG KAL YE GRLLD L P F S R AFYK KL LG KP L S 126
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1537 L H D IVLF D A EL G K T L Q EL R vvvarkhylegvgg DN SSTIS DL C L R gcri EDLS L EFTLP G YP -- E YILRSG D EI V DIT N L 1614
Cdd:cd00078 127 L E D LEEL D P EL Y K S L K EL L -------------- DN DGDED DL E L T ---- FTIE L DSSFG G AV tv E LKPGGR D IP V TNE N K 188
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1615 EEY IS L V VD ATVKR G VTR Q I EAFR S GF NQ V FDITS L QI FTP S EL DY L L CG RRE l WEV E T L AEHIKFDH GY NAK SP A I --- 1691
Cdd:cd00078 189 EEY VD L Y VD YRLNK G IEE Q V EAFR D GF SE V IPEEL L SL FTP E EL EL L I CG SED - IDL E D L KKNTEYKG GY SSD SP T I qwf 267
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1692 INIMGEL T ADQQRA F C QFVTG AP RLP P GG L A V LNPK L TI V R KH S S tssaaangagaseta DD D LP SVM TC A N Y LKLPPYS 1771
Cdd:cd00078 268 WEVLESF T NEERKK F L QFVTG SS RLP V GG F A D LNPK F TI R R VG S P --------------- DD R LP TAH TC F N L LKLPPYS 332
410
....*....|....*...
gi 30692023 1772 T KEI MYK KLLYAINEG Q G 1789
Cdd:cd00078 333 S KEI LRE KLLYAINEG A G 350
HECT
pfam00632 HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl ...
1427-1794
1.56e-97
HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl Terminus.
Pssm-ID: 459880
Cd Length: 304
Bit Score: 316.86
E-value: 1.56e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1427 TLLS HD L QKASL G MWRSSSG D KVSMQ igrdeiedgkpsaanrdivlaplglfpr PW PS TADIS eggq FHKVIE YF RL LG R 1506
Cdd:pfam00632 1 TLLS KE L FDPNY G LFEYETE D DRTYW ---------------------------- FN PS SSESP ---- DLELLD YF KF LG K 48
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1507 VMA KA LQD G R LLD V P LSTA FYK LI LG QE L D L H D IVLF D A EL G K T L QE L RVVVARKH ylegvggdnsstisdlclrgcri E 1586
Cdd:pfam00632 49 LLG KA IYN G I LLD L P FPPF FYK KL LG EP L T L E D LESI D P EL Y K S L KS L LNMDNDDD ----------------------- E 105
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1587 DL S L E FT L P -- G YPEY I -- LRS G DE I - V DIT N L EEYI S L V VD ATVKRGVTR Q I EAFR S GF NQ V FDITS L QI FTP S EL DY L 1661
Cdd:pfam00632 106 DL G L T FT I P vf G ESKT I el IPN G RN I p V TNE N K EEYI R L Y VD YRLNKSIEP Q L EAFR K GF YS V IPKEA L SL FTP E EL EL L 185
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1662 L CG RR E l WE VE T L AEHIKF D H GY NAK SP A I IN --- I MG E LTAD Q Q R A F CQ FVTG AP RLP P GG LAV L n PK L TIVRK HS sts 1738
Cdd:pfam00632 186 I CG SP E - ID VE D L KKNTEY D G GY TKN SP T I QW fwe I LE E FSPE Q R R L F LK FVTG SS RLP V GG FKS L - PK F TIVRK GG --- 260
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 30692023 1739 saaangagase TA DD D LP SVM TC A N Y LKLP P YS T KEI MYK KLL Y AI N EG Q G s F D LS 1794
Cdd:pfam00632 261 ----------- DD DD R LP TAH TC F N R LKLP D YS S KEI LKE KLL I AI E EG E G - F G LS 304
HECTc
smart00119 Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to ...
1403-1789
1.75e-92
Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to E2 enzymes.
Pssm-ID: 214523
Cd Length: 328
Bit Score: 303.39
E-value: 1.75e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1403 Q K A VLE V E YF GE V G - T G L G P T L EF YT LLS HD L QKASL G MW R S S SG D K vsmqigrdeiedgkpsaanrdivlapl G L F P R P 1481
Cdd:smart00119 3 K K R VLE I E FE GE E G l D G G G V T R EF FF LLS KE L FNPDY G LF R Y S PN D Y --------------------------- L L Y P N P 55
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1482 WPST A D iseggqf HKVIE YFR LL GRV MA KAL Q D G RLLD VPLSTA FYK LI LG QELD LHD IVLF D A EL G K T L QE L R vvvark 1561
Cdd:smart00119 56 RSGF A N ------- EEHLS YFR FI GRV LG KAL Y D N RLLD LFFARP FYK KL LG KPVT LHD LESL D P EL Y K S L KW L L ------ 122
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1562 hy L E gvgg DNS S TIS DL C lrgcri EDLS L EFTLPGYPEYI L RS G DEIVDI T -- N LE EY IS LV VDATVKR G VTR Q I EAFR S 1639
Cdd:smart00119 123 -- L N ---- NDT S EEL DL T ------ FSIV L TSEFGQVKVVE L KP G GSNIPV T ee N KK EY VH LV IEYRLNK G IEK Q L EAFR E 190
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1640 GF NQ V FDITS L QI F T P S EL DY L L CG RR E l WE V ET L AEHIKFDH GY N A K S PA I --- INIMGEL T ADQQ R AFC QFVTG AP RL 1716
Cdd:smart00119 191 GF SE V IPENL L KL F D P E EL EL L I CG SP E - ID V DD L KSNTEYKG GY S A N S QT I kwf WEVVESF T NEER R KLL QFVTG SS RL 269
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30692023 1717 P P GG L A V L N PK L TI VRKH S S tssaaangagaseta D DD LP SVM TC A N Y LKLPPYS T KEI MYK KLL Y AINEG Q G 1789
Cdd:smart00119 270 P V GG F A A L S PK F TI RKAG S D --------------- D ER LP TAH TC F N R LKLPPYS S KEI LRE KLL L AINEG K G 327
HUL4
COG5021 Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
1293-1791
1.39e-72
Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 227354 [Multi-domain]
Cd Length: 872
Bit Score: 262.01
E-value: 1.39e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1293 FVNSKLTPK L A R QIQDALALC S GSLPSWCYQLT rac P F L FPFQ TR RQYF Y STA F GLS R - ALNRLQQQQGADGSGSTNERE 1371
Cdd:COG5021 413 TYEDLRREQ L G R ESDESFYVA S NVQQQRASREG --- P L L SGWK TR LNNL Y RFY F VEH R k KTLTKNDSRLGSFISLNKLDI 489
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1372 M RI GRLQ R Q K VRV S RNRILDSAAKVMEMYSSQKA V L E V --- E YFG E V G TG L GP TLE FYTLLSHDLQKAS L GMWR sssgdk 1448
Cdd:COG5021 490 R RI KEDK R R K LFY S LKQKAKIFDPYLHIKVRRDR V F E D syr E IMD E S G DD L KK TLE IEFVGEEGIDAGG L TREW ------ 563
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1449 vs MQIGRD E IEDGKPSA anrd IVLAPLG L FPR P WPSTAD I SE ggqfh KVIE YF RL LGRV MA KA LQ D G R L LDV PL S T AFYK 1528
Cdd:COG5021 564 -- LFLLSK E MFNPDYGL ---- FEYITED L YTL P INPLSS I NP ----- EHLS YF KF LGRV IG KA IY D S R I LDV QF S K AFYK 632
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1529 LI LG QELD L H D IVLF D A EL GKT L QE L R vvvarkhylegvgg D N SSTISD L C L R g CRI ED L S LEFTLP gy P E Y I LRSGDEI 1608
Cdd:COG5021 633 KL LG KPVS L V D LESL D P EL YRS L VW L L -------------- N N DIDETI L D L T - FTV ED D S FGESRT -- V E L I PNGRNIS 695
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1609 V DIT N LE EY ISL VVD ATVKRG V TR Q IE AF R SGF NQVFDITS LQIF TP SEL DY L LC G RR E LWEVETLAEHIK f D HGY NAK S 1688
Cdd:COG5021 696 V TNE N KK EY VKK VVD YKLNKR V EK Q FS AF K SGF SEIIPPDL LQIF DE SEL EL L IG G IP E DIDIDDWKSNTA - Y HGY TED S 774
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 1689 P A I I --- N I MG E LTADQQRAFC QFVTG AP R L P PG G LAV L NPKLTIVRKHS stssaaanga GASE T A DD D LPS VM TC A N Y L 1765
Cdd:COG5021 775 P I I V wfw E I IS E FDFEERAKLL QFVTG TS R I P IN G FKD L QGSDGVRKFTI ---------- EKGG T D DD R LPS AH TC F N R L 844
490 500
....*....|....*....|....*.
gi 30692023 1766 KLP P YS T KE IMYK KLL Y AINEG Q G SF 1791
Cdd:COG5021 845 KLP E YS S KE KLRS KLL T AINEG A G FG 870
SRP1
COG5064 Karyopherin (importin) alpha [Intracellular trafficking and secretion];
138-538
1.55e-04
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
Pssm-ID: 227396 [Multi-domain]
Cd Length: 526
Bit Score: 46.42
E-value: 1.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 138 Q VE A LTQLCEM LS IG T EDSLSTFSVDSF VP VL V GLLNHESNPDIMLL AA R ALT HLCDVLPSSCAA VV HY GAV SCLVAR L L 217
Cdd:COG5064 88 Q LQ A VYKFRKL LS KE T SPPIQPVIDAGV VP RF V EFMDEIQRDMLQFE AA W ALT NIASGTTQQTKV VV DA GAV PLFIQL L S 167
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 218 TI E y M D LA EQ SLQ AL KK I SQEHP t A C ---- L RA GAL MAV L SY L DFFSTGVQ -- R V A LS T AA N M C K - K L P SDASDYVME A V 290
Cdd:COG5064 168 ST E - D D VR EQ AVW AL GN I AGDSE - G C rdyv L QC GAL EPL L GL L LSSAIHIS ml R N A TW T LS N L C R g K N P PPDWSNISQ A L 245
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 291 P L L TN L LQYH D SK VL EY A SICLTRIAEAFA pyp EK LDELCNH G LVTQAAS L I S tsnsgggqa SL S VSTY T GLI R LLSTCA 370
Cdd:COG5064 246 P I L AK L IYSR D PE VL VD A CWAISYLSDGPN --- EK IQAVLDV G IPGRLVE L L S --------- HE S AKIQ T PAL R SVGNIV 313
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 371 S GS PL gfrtllllgissi LKDILLGS G vs A NASVSPA LS R P ADQ I ----- YE I V N LA ------------ NE L L PPL peg V 433
Cdd:COG5064 314 T GS DD ------------- QTQVIINC G -- A LKAFRSL LS S P KEN I rkeac WT I S N IT agnteqiqavid AN L I PPL --- I 375
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692023 434 IS L PTSTNALV K GS C QKK S SPSTS G - KQE DI LK ------- I S P REK LL GDQPELLQQFG LD LL ----------------- 488
Cdd:COG5064 376 HL L SSAEYKIK K EA C WAI S NATSG G l NRP DI IR ylvsqgf I K P LCD LL DVVDNKIIEVA LD AI enilkvgeqdrlrygkn 455
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30692023 489 ---- P V L V QIY G --------- S SVN G TI RH K CL S V I G K lm Y F SSSEMIQS L IGD T NISS F LA G 538
Cdd:COG5064 456 iniy A V Y V EKA G gmdaihglq D SVN R TI YD K AY S I I E K -- F F GEEDAVDE L APE T AGNT F TF G 516
HEAT_EZ
pfam13513 HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
263-315
1.71e-03
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.
Pssm-ID: 463906 [Multi-domain]
Cd Length: 55
Bit Score: 38.12
E-value: 1.71e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 30692023 263 V QRV A LSTAANMCKKL P SDASDY V M E AV P L L TN LL QYHDSK V L E Y A SIC L T R I 315
Cdd:pfam13513 3 V REA A ALALGSLAEGG P DLLAPA V P E LL P A L LP LL NDDSDL V R E A A AWA L G R L 55
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
